Testing Means Inserted In Body Patents (Class 600/486)
  • Patent number: 10499817
    Abstract: Medical devices and methods for making and using medical devices are disclosed. An example method may include a method for calculating fractional flow reserve including providing a pressure sensing guidewire, advancing the pressure sensing guidewire through a blood vessel to a first position distal of an intravascular occlusion, determining a distal pressure within the body lumen with the pressure sensing guidewire, proximally shifting the pressure sensing guidewire to a second position proximal of the occlusion, determining a proximal pressure within the body lumen with the pressure sensing guidewire, measuring an aortic pressure, and calculating a pressure drift. The pressure drift may be the difference between the aortic pressure and the proximal pressure. The method may also include calculating a drift-compensated fractional flow reserve. The drift-compensated fraction flow reserve may correspond to (the distal pressure+the pressure drift) divided by the aortic pressure.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: December 10, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Daniel J. Gregorich
  • Patent number: 10492697
    Abstract: Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire with electrical conductors embedded within a core wire. In some instances, the electrical conductors are coupled to conductive bands adjacent a proximal portion of the guide wire and a sensing element adjacent a distal portion of the guide wire. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: December 3, 2019
    Assignee: VOLCANO CORPORATION
    Inventor: David H Burkett
  • Patent number: 10478249
    Abstract: Apparatus and methods are described, including a method for use with tissue of a renal nerve (770) passing longitudinally within a wall of a renal artery (8) of a subject. Using one or more stimulating electrodes (850a, 850b) disposed within the renal artery, the tissue is stimulated by passing a stimulating current through the wall of the renal artery. Using a sensor (26), a rate of change of blood pressure of the subject is sensed, following the start of the stimulation of the tissue. In response to the rate of change, it is decided whether to ablate the tissue, and in response to deciding to ablate the tissue, the tissue is ablated. Other applications are also described.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: November 19, 2019
    Assignee: PYTHAGORAS MEDICAL LTD.
    Inventors: Yossi Gross, Gideon Meiry, Yehuda Zadok
  • Patent number: 10456048
    Abstract: A sensor device includes an implantable sensor unit, a transponder unit, and a wired connection flexibly and electrically connecting the implantable sensor unit and the transponder unit. The implantable sensor unit is adapted to be implanted into a body. The implantable sensor unit includes a comparator and a sensor adapted to sense a characteristic of the body in vivo. The sensor is adapted to supply an analog signal to a first input of the comparator. The transponder unit is adapted to supply a control signal to the implantable sensor unit and to receive an output signal of the comparator. The implantable sensor unit is adapted to supply an analog approximation signal to a second input of the comparator in response to the control signal. The wired connection is adapted to transmit the control signal and the output signal of the comparator.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: October 29, 2019
    Assignee: Infineon Technologies AG
    Inventors: Peter Bogner, Dirk Hammerschmidt
  • Patent number: 10441221
    Abstract: A medical device, such as a prosthesis, may include a graft material and a pocket disposed along at least one of luminal and abluminal surfaces of the graft material. The pocket may include a pocket opening leading into an enclosed cavity. The enclosed cavity may be sized to receive at least a portion of a microsystem, and the pocket may be accessible in vivo for removal of the microsystem from the pocket.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: October 15, 2019
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventor: Ralf Spindler
  • Patent number: 10433946
    Abstract: A catheter device for transvascular delivery of a medical device to a cardiac valve region of a patient comprises an elongate sheath with a first lumen, a distal end for positioning at a heart valve, a second lumen that extends parallel to or in the sheath, and an expandable embolic protection filter. The filter is arranged to extend from an orifice of the second lumen and, in the expanded, covers ostia of the side branch vessels in the aortic arch.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: October 8, 2019
    Assignee: SWAT Medical AB
    Inventor: Erik Krahbichler
  • Patent number: 10413201
    Abstract: The invention relates to a pressure sensor catheter and method for measuring pressure on a distal side of a flow constriction, such as a stenosis, in a body lumen or measuring a pressure difference over the flow constriction. The catheter includes a pressure transfer tube for passing through the constriction, the tube being connected to and extending from a pressure sensor for transferring the pressure at the distal side of the constriction via the tube to the sensor, and a catheter body for introduction of the catheter into the body lumen, wherein the catheter body comprises the sensor at a sensor position, such that the sensor in use is positioned in the body lumen, and wherein a distal end region of the catheter including the distal end region of the pressure transfer tube has a smaller maximum outer diameter than the outer diameter of the catheter at the sensor position.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: September 17, 2019
    Assignee: Wellinq Medical B.V.
    Inventor: Bas Ludoph
  • Patent number: 10405757
    Abstract: A gatekeeper electronic signal can be generated by a patient sensor and/or in an intermediate device, such as an electrical cable, that is separate from a patient's physiological information electronic signal. The gatekeeper signal can be generated to indicate to a computer monitor that the sensor and/or cable is of the type that is compatible with, and/or usable with, such computer monitor, and/or that the sensor and/or cable is properly attached to the computer monitor. The gatekeeper signal can be created by an ambient temperature sensor on, or in electrical communication with, the patient monitor, and/or the gatekeeper signal can be created by a gatekeeper electronic signal generator to simulate an ambient temperature value. The gatekeeper signal can be separate from an electronic signal or plurality of signals that include patient physiological information, and the gatekeeper signal may not include any patient physiological information.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: September 10, 2019
    Assignee: ICU Medical, Inc.
    Inventors: Timothy John Hughes, Lina Derderian
  • Patent number: 10398409
    Abstract: A transducer cover for use in an ultrasonic medical instrument having a transducer is disclosed. The transducer cover includes a vibration absorbing layer of a generally cylindrical form made of a synthetic resin having a vibration absorbing property, and a chemical blocking layer of a generally cylindrical form made of a synthetic resin which is impermeable to water and chemicals. The vibration absorbing layer and the chemical blocking layer are coaxially laminated, and capable of sealing arrangement over and around the transducer. Also disclosed is an ultrasonic medical instrument having an ultrasonic transducer and the transducer cover, and a method for forming the transducer cover over and around an ultrasonic transducer of an ultrasonic medical instrument.
    Type: Grant
    Filed: November 27, 2010
    Date of Patent: September 3, 2019
    Assignee: Nakanishi Inc.
    Inventors: Masaki Nakagawa, Shinichi Tanaka
  • Patent number: 10385996
    Abstract: Tapering couplers and coupling methods for connecting fluid flow components are provided. In one embodiment, the tapering coupler includes a housing with a first opening and a second opening in fluid communication through the housing. The first opening is sized for a first fluid flow component to couple to the housing, and the second opening for a second fluid flow component. The first and second fluid flow components include first and second fluid-carrying channels of different diameter, with the first fluid-carrying channel having a first channel diameter that is larger than the second channel diameter of the second fluid-carrying channel. A tapering element is associated with the housing and extends into the first fluid-carrying channel. The tapering element includes a tapering fluid-carrying channel which tapers in a direction back towards the housing, for instance, from about the first channel diameter to about the second channel diameter.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: August 20, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Amilcar R. Arvelo, Michael J. Ellsworth, Jr., Eric J. McKeever
  • Patent number: 10376219
    Abstract: A monitoring device for the circulation of a patient includes sensors for recording data, an input unit for inputting patient specific data and a connected a data recording and analysis device configured to determine the right atrial pressure (RAP), the mean arterial pressure (MAP) and the cardiac output (CO) and to determine the mean systemic filling pressure (Pms) and to determine the cardiac efficiency (Eh) therefrom. A device records a pressure value (Pps,char) characterizing the pressure assistance during positive-pressure ventilation. The data recording and analysis device is configured to determine a pressure-corrected mean systemic filling pressure (Pmsp) and a pressure-corrected cardiac efficiency (Ehp) by the difference from the right atrial pressure (RAP) and the pressure value (Pps,char) characteristic of the pressure assistance being used instead of the right atrial pressure (RAP).
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: August 13, 2019
    Assignee: DR√ĄGERWERK AG & CO. KGAA
    Inventors: Michael Imhoff, Ernst-Wilhelm Schubert, Doreen Werner
  • Patent number: 10363350
    Abstract: Apparatus and methods are described including identifying a subject as suffering from cardiac dysfunction, congestive heart failure, reduced renal blood flow, increased renal vascular resistance, arterial hypertension, and/or kidney dysfunction, and, in response thereto, reducing blood pressure within a renal vein of the subject, by activating at least one impeller to pump blood from the renal vein into a vena cava of the subject, by the impeller rotating.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: July 30, 2019
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 10350389
    Abstract: Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire with distal tip element having a radiopaque marker pattern. For example, in some implementations a sensing guide wire includes a flexible elongate member; a sensing element coupled to the flexible elongate member; a flexible tip element coupled to and extending distally from the sensing element, the flexible tip element having a first radiopaque section, a second radiopaque section, and a non-radiopaque section positioned between the first and second radiopaque sections. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: July 16, 2019
    Assignee: VOLCANO CORPORATION
    Inventors: David Burkett, Ramiro Reyes
  • Patent number: 10327695
    Abstract: The present invention generally relates to methods, systems, and apparatuses for determining the degree of improvement after a therapeutic procedure. The method can involve determining a baseline measurement prior to conducting a therapeutic procedure, conducting the therapeutic procedure, and determining a post-therapy measurement after conducting the therapeutic procedure. The method further involves comparing the post-therapy measurement to the baseline measurement, thereby determining the degree of improvement after conducting the therapeutic procedure.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: June 25, 2019
    Assignee: VOLCANO CORPORATION
    Inventor: David Anderson
  • Patent number: 10321958
    Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: June 18, 2019
    Assignee: HeartFlow, Inc.
    Inventor: Charles A. Taylor
  • Patent number: 10322260
    Abstract: In the treatment method, a surgeon introduces a catheter assembly into a blood vessel in an arm, and delivers a distal portion of the catheter assembly to a predetermined position of a lower limb through the blood vessel in the body. Moreover, in the treatment method, the surgeon pulls an inner catheter out of an outer catheter, causes a treatment device to advance to the treatment target through the inside of the outer catheter, and treats the treatment target by the treatment device.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: June 18, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Mariko Ueda, Tetsuya Fukuoka
  • Patent number: 10307055
    Abstract: An image processing apparatus includes: an acquisition unit configured to acquire a tomogram of an eye portion of a patient to be examined; an information acquisition unit configured to acquire information of a predetermined portion and position information of a predetermined tissue structure from the tomogram; and a calculation unit configured to calculate an evaluation value based on a relationship between the information of the predetermined portion and a position of the predetermined tissue structure.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: June 4, 2019
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hiroshi Imamura
  • Patent number: 10307070
    Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for performing intravascular data analysis and measurement of various types of data such as pressure and flow data. The disclosure relates to probes and methods suitable for determining an event in a cardiac cycle such as flow threshold such as a peak flow, a fraction thereof, other intravascular parameters or a point in time during which peak flow or a change in one of the parameters occurs. An exemplary probe includes one or more of a pressure sensor, a resistor, a flow sensor and can be used to generate diagnostic data based upon measured intravascular and other parameters. In part, the disclosure relates to methods and systems suitable for determining a coronary flow reserve value in response to one or more of intravascular pressure and flow data or data otherwise correlated therewith.
    Type: Grant
    Filed: April 4, 2015
    Date of Patent: June 4, 2019
    Assignee: St. Jude Medical Coordination Center BVBA
    Inventors: Eugen Veszelei, Fredrik Lundgren
  • Patent number: 10292653
    Abstract: A mobile healthcare device and method of operating the same are provided. The method includes setting a mode of the mobile healthcare device to a measurement mode, displaying a screen for guiding a user to maintain a predetermined position during the measurement mode, and, in response to a predetermined amount of time passing from a time at which the screen begins to be displayed, obtaining state information of the user based on bio information of the user, the bio information being received from a sensor.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: May 21, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kunsun Eom, Kak Namkoong, Yeolho Lee, Myounghoon Jung, Seongho Cho
  • Patent number: 10274408
    Abstract: Embodiments of the invention include a biosensor, such as an implantable biosensor, that includes a sensor material sensitive to at least one analyte in a pressure measurement chamber coupled to a pressure sensor. In embodiments of the invention, a pressure prevailing in the pressure measurement chamber may be determined by the pressure sensor. The sensor material is coupled in the pressure measurement chamber to a compensation material, which includes a relationship between a temperature and a volume of the pressure. The relationship is opposite to a temperature-dependent change in pressure or volume of the sensor material and at least partially compensates for a cross-sensitivity-induced change in volume of the sensor material.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: April 30, 2019
    Assignee: Biotronik SE & Co. KG
    Inventors: Henning Ebert, Andreas Bunge
  • Patent number: 10271742
    Abstract: Automatic method, as well as the related system and the tools allowing the same to be executed, for measuring and processing blood pressure starting from a detected pressure signal, the method operating in the time domain for discriminating whether the detected signal is an adequate measurement or not and, where it is not, time domain analysis automatically selects a low-pass filter to, possibly iteratively, apply to the detected pressure signal for having correct values and wave form of the blood pressure.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: April 30, 2019
    Inventor: Salvatore Romano
  • Patent number: 10219707
    Abstract: The invention relates to medicine, in particular, to vascular and endovascular surgery. The objective of the invention is to measure pressure and to administer drugs to an aneurysm in a blood vessel after implantation of a stent-graft. The device for measurement of pressure and for administration of drugs is made of a shape memory material, in the form of a hollow tube with side apertures.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: March 5, 2019
    Inventor: Zaza Alexandrovich Kavteladze
  • Patent number: 10201284
    Abstract: Bending stresses experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending stresses, the sensor is mounted with one end coupled to the distal end of the shaft while the other end of the sensor is not coupled to the catheter so that a portion of the sensor is spaced apart from the distal end of the shaft.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: February 12, 2019
    Assignee: MEDTRONIC VASCULAR INC.
    Inventors: Gerry McCaffrey, Fiachra Sweeney, Christopher Murphy
  • Patent number: 10195425
    Abstract: This application describes a miniature implantable neurostimulator system for sciatic nerves and their branches. The implanted miniature neurostimulator is implanted in the leg and stimulates these nerves for the treatment of urinary or bowel incontinence. The miniature implantable neurostimulator has a low duty cycle permitting a small size with medically-acceptable longevity. The system includes a wireless programmer and patient-activated key fob.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: February 5, 2019
    Assignee: Nine Continents Medical, Inc.
    Inventors: Alan Ostroff, Peter Jacobson
  • Patent number: 10184851
    Abstract: Apparatus and methods for a MEMS-fabricated variable capacitor. In one embodiment the capacitor is a comb drive comprising a plurality of plates interdigitated with a corresponding blades. As the plates move relative to the blades, the capacitance of the sensor changes. The capacitor is sufficiently sensitive to measure respiratory pressure in an animal.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: January 22, 2019
    Assignees: Indiana University Research and Technology Corporation, Purdue Research Foundation
    Inventors: A. George Akingba, Jason V. Clark
  • Patent number: 10173069
    Abstract: A fixation device configured to anchor an implantable medical device within a patient includes a temporary biodegradable fixation mechanism configured to secure the device after implantation until the temporary fixation mechanism biodegrades and a chronic fixation mechanism configured to promote tissue growth that secures the device to tissue of the patient before the temporary fixation mechanism biodegrades.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: January 8, 2019
    Assignee: Medtronic, Inc.
    Inventors: Robert T. Taepke, II, Ya Guo, Joseph D. Berglund
  • Patent number: 10172539
    Abstract: Quantitatively determining an amount of reperfusion in an artery after angioplasty and quantitatively assessing an effectiveness of thrombolysis by non-invasively sensing from outside the subject mechanical vibrations from a mechanical contraction of at least one ventricle to simultaneously measure (a) IVCT (time duration of an isovolumetric contraction portion of a systole phase) and (b) a peak endocardial acceleration (PEA) during the IVCT. PEA is measured before and after opening the artery (or before and after thrombolysis) and in some embodiments one calculates a myocardial contractility index (MCI) of the subject, for example MCI=PEA/IVCT. A determination unit compares the first and second PEA (or the first and second MCI), and then determines an amount of reperfusion based on the comparison. The amount of reperfusion is proportionate to a viable myocardium and, in the case of thrombolysis, the amount of reperfusion quantitatively assesses the effectiveness of thrombolysis.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: January 8, 2019
    Assignee: CORSENS MEDICAL LTD.
    Inventor: Alon Marmor
  • Patent number: 10149723
    Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: December 11, 2018
    Assignee: HeartFlow, Inc.
    Inventor: Charles A. Taylor
  • Patent number: 10136906
    Abstract: A device, method, and system of deploying an embolic protection device at a location distal to a treatment site in a vessel of a patient. A delivery catheter is encircled by a sealing member which is expandable from a delivery configuration to a deployed configuration. The device creates a seal to prevent the flow of blood during the treatment of vascular disease. A distal protection element is delivered by the delivery catheter and deployed to filter or remove embolic debris.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: November 27, 2018
    Assignee: Covidien LP
    Inventor: Richard S. Kusleika
  • Patent number: 10118016
    Abstract: A method of detecting and treating a microvascular obstruction is provided. In one embodiment, a catheter is provided for both detecting the microvascular obstruction and treating or removing the obstruction.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: November 6, 2018
    Assignee: Osprey Medical, Inc.
    Inventors: Robert S. Schwartz, Robert A. Van Tassel
  • Patent number: 10105067
    Abstract: The devices and methods generally relate to vibratable sensors for measuring ambient fluid pressure, in particular implantable sensors. The devices and methods are particularly well-suited to implantation within the body of a living animal or human to monitor physiological conditions, such as portal and/or hepatic venous blood pressure, and allow frequent, remote interrogation of venous pressure using the resonance frequency of an implanted sensor. The sensor devices are relatively small compared to conventional devices for measuring fluid pressure and can be implanted in the porto-hepatic venous system, whereas conventional devices are too large. The small size of the device is accomplished by using a thick sensor membrane, compared to conventional devices, and by limiting the size of additional elements of the device relative to the size of the sensor membrane. The thicker sensor member also obviates the need for multiple sensor arrays and maintains the accuracy and robustness of the sensor device.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: October 23, 2018
    Assignee: Microtech Medical Technologies Ltd.
    Inventors: Yoram Richter, Eric S. Tammam, Shahar Even-Dar Mandel
  • Patent number: 10105480
    Abstract: The invention relates to a control unit (30) for determining the pressure in a blood vessel (A, V, F), in particular in an arteriovenous fistula (F), which is in fluid connection with at least one section (28, 41) of a blood line system (39), in particular an extracorporeal blood circulation (II), at least one pressure-generating device (3, 8, 19, 24, 26) being assigned to the blood line system (39), this pressure-generating device being suitable for acting on the section (28, 41), and the control unit (30) being configured to perform the following steps: a) being sure that none of the at least one pressure-generating device (3, 8, 19, 24, 26) acts on the section (28, 41), b) interrupting the fluid connection of the section (28, 41) with the blood vessel (A, V, F) by triggering an interrupt means (11, 29), c) setting the pressure in the section (28, 41) at a predetermined ideal value, in particular at the ambient pressure, with the help of a pressure sensor (13, 14) in the section (28, 41), d) restoring the
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: October 23, 2018
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventor: Pascal Kopperschmidt
  • Patent number: 10099009
    Abstract: A catheter having a secondary port that enables flushing a fluid from a portion of the catheter. The secondary port is disposed along the length of the catheter tube so as to be near an entry point of the catheter into a patient's body. A clamp is disposed adjacent to the secondary port on a side proximate to the patient's body. The secondary port and clamp enable flushing of a fluid from a portion of the catheter that is external to the patient's body and disposal of a clot- or obstruction-dissolving agent into the external portion of the catheter. Upon removal of the clot or obstruction, the secondary port and clamp enable removal of the dissolving agent and replenishing the fluid in the external portion of the catheter to resume provision of the fluid to the patient.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: October 16, 2018
    Inventor: Judith L. Anderson
  • Patent number: 10085425
    Abstract: An electronic apparatus is provided which, even when the electronic apparatus configuring a node is implanted in the body of an object animal, makes the object animal hard to feel stress and can acquire effective data about the natural behavior and state of the object animal. As shown in FIG. 12, a module unit and a battery are arranged separated from each other. That is, an electronic apparatus according to the present embodiment 1 adopts a case including a first capacity part and a second capacity part both arranged separated from each other to thereby accommodate the module unit in an internal space of the first capacity part and accommodate the battery in an internal space of the second capacity part.
    Type: Grant
    Filed: June 27, 2015
    Date of Patent: October 2, 2018
    Assignee: RENESAS ELECTRONICS CORPORATION
    Inventors: Takuo Funaya, Tomohiro Nishiyama, Hiroki Shibuya, Manabu Okamoto
  • Patent number: 10039874
    Abstract: Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of: cardiac dysfunction, congestive heart failure, reduced renal blood flow, increased renal vascular resistance, arterial hypertension, and kidney dysfunction. In response thereto, blood pressure within a renal vein (32) of the subject is reduced, by placing a blood pump (150) inside the subject's renal vein and activating the impeller to pump blood from the renal vein into the subject's vena cava (26). Other applications are also described.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 7, 2018
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 10016563
    Abstract: A syringe barrel includes an barrel main body having a female luer at a distal end of the barrel main body, the female luer being configured such that a male luer is insertable into and connectable to the female luer; and a cap that is detachably attached to the female luer to close an opening of the female luer. The female luer has a female luer-side connector, and the cap is detachably attached to the female luer via the female luer-side connector. The cap includes an insertion part inserted into the female luer, a sealing part that seals the opening of the female luer, and a cap-side connector that is detachably engaged with the female luer-side connector.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: July 10, 2018
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Aiko Horiuchi, Tomoyuki Hojo, Hitoshi Okihara
  • Patent number: 10010673
    Abstract: A system for modulating delivery of a fluid medium to a selected site within a patient's body includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a medium reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The syringe includes a chamber for receiving the fluid medium therein. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe, and simultaneously increase medium fluid flow resistance with increasing pressure level of the fluid medium within the flow diverter assembly.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: July 3, 2018
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Patent number: 9993168
    Abstract: There is provided an implantable pressure monitor having a fluid sack in contact with a body part of a patient where the fluid sack is retained to the body part by a pressure monitor housing that may have various attachment means. The fluid sack is filled with a liquid such as silicone oil. The pressure monitor housing has an opening that provides access to a fistula with a fluid valve that terminates through the fluid sack. A fiber optic pressure sensor is in contact with the liquid in the fluid sack by way of the fistula and fluid valve. In some embodiments of the present invention, an electronics module is incorporated with the implantable pressure monitor to provide telemetry, power, and the like.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: June 12, 2018
    Assignee: University of Rochester
    Inventors: Jason Haitao Huang, Samantha Dayawansa
  • Patent number: 9993279
    Abstract: A cryoablation method, system, and device that allows for real-time and accurate assessment and monitoring of PV occlusion and lesion formation without the need for expensive imaging systems and without patient exposure to radiation. The system includes a cryoballoon catheter with a cryoballoon, a distal electrode, a proximal electrode, and a temperature sensor. Impedance measurements recorded by the electrodes may be used to predict ice formation, quality of pulmonary vein occlusion, and lesion formation.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: June 12, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Boaz Avitall, Catherine R. Condie
  • Patent number: 9987095
    Abstract: A force transmitting assembly of an adapter assembly includes a rotatable drive shaft, a strain sensor, and a drive member. The drive shaft includes a proximal portion, a distal portion, and a flange. The distal portion includes a threaded portion. The strain sensor is coupled to the drive shaft and disposed adjacent the flange such that longitudinal movement of the drive shaft imparts a force on the strain sensor via the flange. The distal drive member has a proximal end rotatably coupled to the threaded portion of the drive shaft and a distal end configured to be operatively coupled to a driven member of a surgical loading unit. Rotation of the drive shaft longitudinally moves the drive member relative to the drive shaft to actuate the surgical loading unit.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: June 5, 2018
    Assignee: Covidien LP
    Inventors: David Chowaniec, Russell Pribanic, Stanislaw Marczyk, Earl Zergiebel, Philip Irka, Anand Subramanian, Paul Richard
  • Patent number: 9974443
    Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. The methods can include obtaining pressure measurements from first and second instruments positioned within a vessel of a patient while the second instrument is moved longitudinally through the vessel from a first position to a second position and the first instrument remains stationary within the vessel; and outputting a visual representation of the pressure measurements obtained by the first and second instruments on a display, the output visual representation including a graphical display of a pressure ratio of the obtained pressure measurements and at least a portion of a pressure waveform of the obtained pressure measurements identifying a diagnostic period utilized in calculating the pressure ratio.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: May 22, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Fergus Merritt, Vaishali Mittal
  • Patent number: 9974508
    Abstract: Non-invasive systems and methods for determining fractional flow reserve. At least one method of determining fractional flow reserve within a luminal organ of the present disclosure comprising the steps of positioning a monitoring device external to a luminal organ and near a stenosis, the monitoring device capable of determining at least one characteristic of the stenosis, operating the monitoring device to determine the at least one characteristic of the stenosis, and determining fractional flow reserve at or near the stenosis based upon the at least one characteristic determined by the monitoring device.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: May 22, 2018
    Inventors: Ghassan S. Kassab, Yunlong Huo
  • Patent number: 9973867
    Abstract: Cochlear implant headpieces with improved moisture resistance.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: May 15, 2018
    Assignee: Advanced Bionics AG
    Inventor: Manish Vaishya
  • Patent number: 9931044
    Abstract: Methods and apparatus for measuring pressure in a patient are provided which may include any number of features. One feature is a pressure measurement system comprising a pressure source, a compliant bladder, a catheter in communication with the pressure source, pressure sensors, and a controller configured to determine a pressure within the compliant bladder. The pressure measurement system can inflate the compliant bladder with gas or air to determine a pressure within a patient. In one embodiment, the pressure measurement system measures pressure within a peritoneal cavity.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: April 3, 2018
    Assignee: Potrero Medical, Inc.
    Inventors: Daniel R. Burnett, Byron Reynolds, Brian M. Neil, Gregory W. Hall, Paul B. Guerra
  • Patent number: 9927316
    Abstract: A micro-electro-mechanical system (MEMS) chip for measuring a pressure in a pressure space includes a MEMS substrate having a measuring region, a contact-making region connected to the measuring region via lines and having contacts, and a bushing region disposed between the measuring region and the contact-making region. The MEMS substrate defines a cavity formed as a blind hole that defines an opening through one side of the MEMS substrate, the bottom of the blind hole forming a membrane. A measuring bridge includes piezoresistive elements disposed on that side of the membrane which faces away from the cavity's opening. A carrier substrate is disposed over the cavity's opening and bonded to the MEMS substrate in a two-dimensional manner to form a rod, with the result that the carrier substrate forms a bottom wall of the cavity spaced apart from the membrane.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: March 27, 2018
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNT E.V.
    Inventors: Stephane Kuehne, Claudio Cavalloni, Andreas Goehlich
  • Patent number: 9901262
    Abstract: A transducer holder assembly for attachment to a patient includes a support member with a contact surface and an oppositely disposed connection surface. The support member includes at least one electrode disposed on the contact surface. A first mating member is coupled to the connection surface. A housing is configured to receive and hold at least a portion of a transducer. The housing includes a second mating member configured to releasably mate with the first mating member via a snap-fit mechanism.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: February 27, 2018
    Assignee: PROMEDICA HEALTH SYSTEM, INC.
    Inventor: Lee Hammerling
  • Patent number: 9901260
    Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: February 27, 2018
    Assignee: ACIST Medical Systems, Inc.
    Inventors: Dale R. Manstrom, Amy R. Raatikka, Robert F. Wilson, Edward R. Miller, Jung Kwon Pak
  • Patent number: 9826910
    Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, a guidewire system for treating a patient includes an internal sensor mount having a body and a first cutout extending through a wall of the body; a core wire secured to the internal sensor mount; a sensor assembly for detecting a physiological characteristic of a patient secured to the internal sensor mount; an external housing disposed about the internal sensor mount and including an opening in communication with the cutout of the internal sensor mount; a proximal flexible member secured to at least one of the internal sensor mount and the external housing; a first distal flexible member secured to at least one of the internal sensor mount and the external housing; and at least one conductor electrically coupled to the sensor assembly and extending proximally beyond the internal sensor mount through the proximal flexible member.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: November 28, 2017
    Assignee: VOLCANO CORPORATION
    Inventor: David H. Burkett
  • Patent number: 9820660
    Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. In some embodiments, the devices, systems, and methods of the present disclosure are configured to optimize proximal and distal pressure measurements utilized to assess the vessel.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: November 21, 2017
    Assignee: VOLCANO CORPORATION
    Inventors: S. Eric Ryan, Fergus Merritt
  • Patent number: 9816885
    Abstract: An optical force sensing element for microsurgical instruments and methods measures force F in three orthogonal directions and includes a monolithic cylinder structure, a cylindrical surface and a top surface that absorbs and transmits the force F. Three punch-like notches, all being parallel to the y-direction, are spaced apart along the z-axis and form two blades between the first and second notch and between the second and the third notch. Three channels parallel to the z-axis extend from the bottom surface to the top surface and cross the first notch while bypassing the other two notches. Three optical fibers, each fixed in one of the three channels, all entering the structure from the bottom surface, cross the first notch and end at or near the top surface while being interrupted in the first notch and forming two surfaces of each fiber that define a Fabry-Perot interferometric cavity.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: November 14, 2017
    Assignee: SENSOPTIC, SA
    Inventors: Axel Bertholds, Pere Llosas, Simon Henein