Testing Means Inserted In Body Patents (Class 600/486)
  • Patent number: 11490871
    Abstract: According to one embodiment, there is provided an X-ray diagnostic apparatus which comprises an X-ray generation unit configured to irradiate an object with X-rays; an X-ray detection unit configured to detect X-rays applied by the X-ray generation unit and transmitted through the object; an image generation unit configured to generate an X-ray image based on X-rays detected by the X-ray detection unit; a recording unit configured to record pressure data acquired by using a pressure sensor provided on a guide wire; a measurement position setting unit configured to set a measurement position for a pressure by the pressure sensor using the X-ray image; and a display unit configured to display the X-ray image almost in real time and superimpose and display the measurement position set by the measurement position setting unit.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: November 8, 2022
    Assignee: Canon Medical Systems Corporation
    Inventor: Satoru Ohishi
  • Patent number: 11357968
    Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: June 14, 2022
    Assignees: ABIOMED, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE BRIGHAM AND WOMEN'S HOSPITAL INC.
    Inventors: Ahmad El Katerji, Qing Tan, Christian Moyer, Alexander Ship, Sonya Sanat Bhavsar, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller
  • Patent number: 11331104
    Abstract: An example system for detecting leakage around an occlusive implant disposed in the left atrial appendage includes an elongate shaft having a port disposed at a distal end region thereof and a first sensor disposed adjacent the elongate shaft. The elongate shaft is configured to be positioned adjacent the occlusive implant such that the first sensor is positioned on a first side of the occlusive implant and the port is positioned on a second side of the occlusive implant. Further, the first sensor is configured to measure a first parameter and the first parameter is utilized to determine a fluid leak between the occlusive implant and a tissue wall defining the left atrial appendage.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: May 17, 2022
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Joshua Mark Inouye, Alex Pflugfelder, Brian T. Berg, David John Onushko, James M. Anderson, Markus Petteri Lohi
  • Patent number: 11331023
    Abstract: An apparatus includes a catheter, an introducer having a first member and a second member, a locking mechanism coupled to a distal end of the first member and configured to couple the introducer to a peripheral intravenous line, and an actuator coupled to the catheter. The actuator is configured to move from a first configuration, in which the catheter is disposed within the introducer, toward a second configuration to move the second member to a distal position relative to the first member. A portion of a guide of the second member being distal to the first member when the second member is in the distal position. The actuator is configured to move relative to the second member to be placed in the second configuration when the second member is in its distal position such that the catheter is disposed within and extending past an end of the peripheral intravenous line.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: May 17, 2022
    Assignee: Velano Vascular, Inc.
    Inventors: Pitamber Devgon, Richard Thomas Briganti, Kenneth Todd Cassidy, Marc-Alan Levine, Mark Martel
  • Patent number: 11330989
    Abstract: A catheter, such as a fractional flow reserve catheter, includes an elongate shaft having a proximal end optionally coupled to a handle or luer fitting and a distal end having a distal opening. A pressure sensing wire extends to the distal portion of the elongate shaft to be coupled to a pressure sensor mounted on the distal end for measuring a pressure of a fluid within lumen of vessel. The pressure sensor wire is disposed within a pocket formed adjacent to the pressure sensor thereby minimizing the profile of the catheter. Bending or flexing stress or strain experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending or flexing stress and strain, the sensor is mounted so that the sensor is spaced apart from the elongate shaft of the catheter.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: May 17, 2022
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Gerry McCaffrey, Christopher Murphy, Fiachra Sweeney, John Kelly
  • Patent number: 11304665
    Abstract: Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: April 19, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Puneet Sharma, Saikiran Rapaka, Xudong Zheng, Ali Kamen, Lucian Mihai Itu, Bogdan Georgescu, Dorin Comaniciu, Thomas Redel, Jan Boese, Viorel Mihalef
  • Patent number: 11284805
    Abstract: A blood pressure estimating apparatus includes: a detecting unit that detects a first parameter representing a period length being a length of a period of a heartbeat of a living body; a processing unit that determines, using the detected first parameter, a change of a volume of at least one vessel among a plurality of vessels that resiliently deform in a mathematical model with respect to time, the mathematical model expressing blood flowing in a circulatory system of the living body with fluid flowing through a flow path formed by annularly coupling the plurality of vessels, and estimates blood pressure of the blood using the determined change and the mathematical model.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: March 29, 2022
    Assignee: TOHOKU UNIVERSITY
    Inventor: Toshiyuki Hayase
  • Patent number: 11272847
    Abstract: A system comprising a multi-sensor catheter for monitoring of a cardiac hemodynamic condition, e.g. heart failure, is disclosed. The multi-sensor catheter comprises multi-lumen catheter tubing comprising first and second optical pressure sensors, and their respective optical fibers and connectors. For right heart and pulmonary artery catheterization, a flow-directed multi-sensor catheter comprises a guidewire lumen, an inflatable balloon tip, and sensor locations are configured for placement of a sensor in each of the right atrium and pulmonary artery, for measurement of central venous pressure in the right atrium and a pulmonary artery pressure. An optical fiber for oximetry may be included. The outside diameter is small enough for insertion through a vein of the arm. For monitoring of a left atrial shunt, sensors of a multi-sensor catheter are configured for measuring pressures upstream and downstream of the shunt, e.g. in the left and right atria, or left atrium and coronary sinus.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: March 15, 2022
    Assignee: HemoCath Ltd.
    Inventors: Christopher Glover, Eric Caron, Sylvain Abel
  • Patent number: 11246661
    Abstract: The present disclosure relates generally to the assessment and treatment of vessels, including for percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). For example, some embodiments of the present disclosure are suited for identifying the available intervention technique(s) suitable to achieve a desired outcome selected or input by a user. For example, in some implementations a method comprises receiving pressure measurements obtained by one or more intravascular pressure-sensing instruments positioned within a vessel of a patient; receiving an input from a user regarding a desired pressure value for the vessel of the patient; identifying an available treatment option based on the received pressure measurements and the desired pressure value; and outputting, to a display device, a screen display including a visual representation of the available treatment option. Related devices and systems are also described.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: February 15, 2022
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventor: Justin Davies
  • Patent number: 11234702
    Abstract: Interatrial shunts having incorporated physiologic sensors are provided for monitoring and treating cardiovascular syndromes, including heart failure and pulmonary hypertension, in which the one or more sensors are affixed to the shunt to measure a physiologic parameter within the interatrial shunt. The one or more sensors may be directly affixed to or within a lumenal surface of the shunt or may be disposed on a support structure in a spaced relation to the shunt lumen, the one or more sensors disposed at locations subject to little or no pannus formation or cardiac wall motion artifact.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: February 1, 2022
    Assignee: V-Wave Ltd.
    Inventors: Neal Eigler, Erez Rozenfeld, Nir Nae, Nathan Bukhdruker, Lior Rosen, James S. Whiting, John Wardle, Werner Hafelfinger
  • Patent number: 11179042
    Abstract: A system and method for characterising a narrowing in a fluid filled tube, the system comprising: a probe having a first measurement sensor to take an instantaneous measurement at different locations along the tube; a mechanism to draw the probe through the tube; a position measure to provide location data relating to the location at which a respective instantaneous measurement is taken by the first measurement sensor; a processor to calculate, from the instantaneous measurements, a characteristic of the tube at different locations along the tube.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: November 23, 2021
    Assignee: MEDSOLVE LIMITED
    Inventors: Helen Catherine Stuart Davies, Justin Davies
  • Patent number: 11154207
    Abstract: An implantable medical device, such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation assembly that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation assembly is formed having at least one flexible asymmetric connector where each fixation member includes a plurality of loops, wherein a first loop of the plurality of loops has a maximum pitch that is different from a maximum pitch of a second loop of the plurality of loops. The attachment of the housing and the fixation assembly includes providing a tubular member that is welded to the housing and crimped over a section of the fixation assembly.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: October 26, 2021
    Assignee: Medtronic, Inc.
    Inventors: Michael P. Campbell, George Patras, Michael A. Schugt, Amir R. Zamiri, Richard J. O'Brien, Ruth N. Klepfer
  • Patent number: 11147461
    Abstract: A blood pressure analyzing apparatus includes: a blood pressure variation determiner determining whether first blood pressure information varies a threshold or more from second blood pressure information or not, the first blood pressure information corresponding to an arbitrary beat, the second blood pressure information corresponding to a previous beat to the arbitrary beat; a blood pressure variation cause determiner determining whether a blood pressure variation is caused by the move of the wrist or by another reason than the move of the wrist, based on, wrist move information detected in a detection period of a pulse wave serving as a calculation source of the first blood pressure information, when it is determined that the first blood pressure information varies the threshold or more from the second blood pressure information; and a recording controller recording a determination result and the first blood pressure information in association with each other.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: October 19, 2021
    Assignee: OMRON HEALTHCARE Co., Ltd.
    Inventors: Kentaro Mori, Shingo Yamashita
  • Patent number: 11141566
    Abstract: A steering tool includes an internal tube disposed inside an external tube. The internal and external tubes are arranged for longitudinal axial movement relative to one another. A distal portion of the internal tube is fixedly joined to a distal portion of the external tube. At least one of the tubes may include, over at least some of its length, two continuous, longitudinal zones of solid material separated from each other by a longitudinal gap. At least one of the tubes may include a flexible distal portion distal to the joining zone, the flexible distal portion being more flexible than other portions of that tube.
    Type: Grant
    Filed: November 6, 2016
    Date of Patent: October 12, 2021
    Assignee: Bendit Technologies Ltd.
    Inventor: Oz Cabiri
  • Patent number: 11122975
    Abstract: A miniature, low power electronic pressure sensor with a first, oil-filled chamber to protect its microelectromechanical systems (MEMS) pressure sensitive membrane and a second chamber filled with saline or body fluids connected by tube into an organ in the body, such as an eyeball, that needs pressure sensing, is described. The tube carries pressure from a sensitive area within the organ to the electronic pressure sensor. The pressure sensor may communicate wirelessly with external readers and pass data to a server or other computer. Running alongside the tube is another tube for draining and pressure relief. The tubes, or cannulas, can share an opening into the organ in order to minimize the number of holes needed. The tubes may be molded into a single oval cross section, combined coaxially, or share a lumen for a portion that enters the wall of an organ so as to promote healing.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: September 21, 2021
    Assignees: California Institute of Technology, University of Southern California
    Inventors: Damien C. Rodger, Yu-Chong Tai, Mark S. Humayun, Aubrey M. Shapero, Abhinav Agarwal, Azita Emami
  • Patent number: 11122980
    Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. In some instances, a method of evaluating a vessel of a patient includes moving a second instrument longitudinally through a vessel of the patient from a first position to a second position while maintaining a first instrument in a fixed longitudinal position with respect to the vessel; obtaining pressure measurements from the first and second instruments while the second instrument is moved longitudinally through the vessel; visually depicting the vessel on a display based on the obtained pressure measurements; and modifying the visual depiction of the vessel to simulate one or more treatment options. Systems for performing such methods are also provided.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: September 21, 2021
    Assignee: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
    Inventor: Justin Davies
  • Patent number: 11103714
    Abstract: Various embodiments of a sealed package and a method of forming the package are disclosed. The package can include a housing extending along a housing axis between a first end and a second end, and an electronic device disposed within the housing that includes a device contact. The package can also include an external contact hermetically sealed to the housing at the first end of the housing, and a conductive member electrically connected to the external contact and the device contact such that the conductive member electrically connects the electronic device to the external contact. The conductive member is compressed between the external contact and the device contact.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: August 31, 2021
    Assignee: Medtronic, Inc.
    Inventors: Michael W. Barror, John K. Day, David A. Ruben, James D. Bradley
  • Patent number: 11058354
    Abstract: Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be included with the access needle to provide image data and/or cardiac waveform information of the subject.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: July 13, 2021
    Assignee: University of Virginia Patent Foundation
    Inventors: Srijoy Mahapatra, George T. Gillies, Jason M. Tucker-Schwartz
  • Patent number: 11052238
    Abstract: Apparatus and methods are described for use with a tributary vessel of a subject that supplies a vein of the subject. Blood within the tributary vessel is mechanically isolated into a compartment that is separated from blood within the vein. Blood flow from the tributary vessel to the vein is controlled by pumping blood from the compartment to the vein. Other applications are also described.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: July 6, 2021
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 11045105
    Abstract: The present disclosure relates to a method for determination of cardiac output or EPBF of a mechanically ventilated subject. The method comprises the steps of introducing a change in the effective ventilation of the subject, measuring expiratory flow and CO2 during a sequence of analyzed breaths during which the effective ventilation of the subject varies, and determining the cardiac output or EPBF of the subject using the flow and CO2 measurements. The method further comprises the steps of measuring also a relative variation in cardiac output or EPBF during the sequence of analyzed breaths, and using the relative variation in the determination of cardiac output or EPBF.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: June 29, 2021
    Assignee: MAQUET CRITICAL CARE AB
    Inventor: Magnus Hallbäck
  • Patent number: 11040140
    Abstract: The invention provides methods for diagnosing and treating deep vein thrombosis and other conditions associated with occluded or constricted vessels. According to certain aspects, methods of the invention involve inserting a sensing device into a vessel having a thrombus therein, assessing, with the sensing device, one or more functional parameters within the vessel, determining an interventional therapy for treating the thrombus based on the assessing step; and performing the interventional therapy.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: June 22, 2021
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: John Unser, Joseph Edward Brown, Marja P. Margolis, Mary Lynn Gaddis
  • Patent number: 11013428
    Abstract: Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be used to provide cardiac waveform information of the subject. A current location of the needle may be distinguished from another location based on an algorithm including the pressure frequency information and the cardiac waveform information.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: May 25, 2021
    Assignee: University of Virginia Patent Foundation
    Inventors: Srijoy Mahapatra, George T. Gillies, Jason M. Tucker-Schwartz
  • Patent number: 11000195
    Abstract: An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the patient. A sensor module configured to measure a blood vessel blood pressure waveform is included, the sensor module having a proximal portion and a distal portion, the distal portion being insertable within the lumen and the proximal portion extending outward from the first open end.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: May 11, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I. Joseph, Apurva Jain, Jonathan Goettler, Nance Dicciani, Denise Devine
  • Patent number: 10980431
    Abstract: A monitoring device is included in a medical system to implement a method for prediction of a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment such as dialysis. To this aim, a pulse shape parameter (pPS) with respect to a pulse generator of the subject is registered by means of a pressure sensor arranged in an extracorporeal blood flow circuit coupled to a cardiovascular system of the subject (P). The pressure sensor is configured to detect pressure variations in blood vessels of the subject (P). It is investigated, during measurement period, whether or not one or more of the pulse shape parameters fulfil a decision criterion. An output signal (a) is generated if the decision criterion is found to be fulfilled, to indicate a predicted rapid symptomatic blood pressure decrease in the subject (P).
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: April 20, 2021
    Assignee: GAMBRO LUNDIA AB
    Inventors: Bo Olde, Kristian Solem
  • Patent number: 10966646
    Abstract: An apparatus and method for collecting a predetermined amount of blood or other fluid using an automated sampling system is provided.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: April 6, 2021
    Assignee: Phlebotics, Inc.
    Inventors: Candice B. Kissinger, Peter Kissinger
  • Patent number: 10953215
    Abstract: The present disclosure provides a medical connector for enteral applications. The medical connector includes a body portion having a distal patient access fitting and a proximal fluid delivery device fitting as well as an administration port. The administration port for administrating or extracting fluids or medicine includes a cylindrical cavity, an administration port seal having a normally-closed slit, a plunger, a plunger sleeve, and a compression member. Engaging a non-luer female tip with the administration port actuates the compression member such that the plunger pierces the normally-closed slit, causing it to open allowing fluid communication with the body portion.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: March 23, 2021
    Assignee: DALE MEDICAL PRODUCTS, INC.
    Inventors: David Preston Adams, Alan Kenneth Stratton, Joseph A. Zilaro, Sharon Steeves, Raymond Gruneberg
  • Patent number: 10945650
    Abstract: Inside a connector body (112, 114; 300) of a medical connector providing a fluid flow conduit, a one-way valve (118) is fitted directly into one end of a stop valve (116) in a manner providing a fluid tight seal between these valves. The stop valve (116) prevents fluid flowing out of the end (111; 311) of the connector body (112, 114; 300) unless a complementary end of a separate device (not shown), typically a Luer lock connector, engages the end of the connector body and opens the stop valve (116). To facilitate manufacture and assembly, the one-way valve (118) and the stop valve (116) can be formed as parts of a single piece of elastomeric material, the parts being hingedly connected so that the one-way valve part (118) can be folded over to be fitted directly into the end of the stop valve part (116). A further possibility, also applicable when only a stop valve (116) is provided, is that the connector body (300) may be formed in one piece with a folding, snap fit closure (312).
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: March 16, 2021
    Assignee: Medical Device Creations Limited
    Inventor: Peter Jeffrey
  • Patent number: 10912463
    Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: February 9, 2021
    Assignees: PHILIPS IMAGE GUIDED THERAPY CORPORATION, MEDSOLVE LIMITED, IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
    Inventors: Justin Davies, Joseph Burnett, Neil Hattangadi, David Anderson, Helen Catherine Stuart Davies
  • Patent number: 10905886
    Abstract: An implantable medical device (IMD) may be configured for deployment at a patient's atrioventricular septum in order to sense and/or pace a patient's heart. The atrioventricular septum of the patient's heart may have an atrial facing side defining part of the right atrium of the patient's heart and a ventricle facing side defining part of the left ventricle of the patient's heart. The IMD may include a first component configured to be positioned at least in part in the right atrium of the patient's heart proximate the atrioventricular septum, and a second component configured to be positioned at least in part in the left ventricle.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: February 2, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventor: Lili Liu
  • Patent number: 10905381
    Abstract: A blood pressure correction information generating device includes: a wrist position change time period detecting section which detects a change time period when a position of a wrist of a person is changed at a degree equal to or greater than a threshold based on information according to a motion of the wrist of the person to whom a blood pressure measurement device is attached, the blood pressure measurement device including a pulse wave detecting section which detects a pulse wave, and a blood pressure information calculating section which calculates blood pressure information; and a blood pressure correction information generating section which generates blood pressure correction information for correcting the blood pressure information which is calculated after the change time period, based on first blood pressure information which is calculated before the change time period, and second blood pressure information which is calculated after the change time period.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: February 2, 2021
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventors: Shingo Yamashita, Kentaro Mori, Yuki Ota
  • Patent number: 10896530
    Abstract: A medical information processing apparatus according to an embodiment includes processing circuitry. The processing circuitry acquires a first index value obtained based on fluid analysis that is performed based on an image including a blood vessel of a subject, the first index value being related to blood flow at each of positions in the blood vessel. The processing circuitry acquires external information including a second index value related to blood flow at each of the positions in the blood vessel. The processing circuitry changes one of an arrangement direction of index values in a first graph and an arrangement direction of index values in a second graph in accordance with the other one of the arrangement directions. The processing circuitry displays the first graph and the second graph on a display unit such that the arrangement directions of the index values match each other.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: January 19, 2021
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventor: Takuya Sakaguchi
  • Patent number: 10894144
    Abstract: A delivery system for an intracorporeal device includes a sheath defining one or more lumens shaped to receive a delivery catheter or shaft and a guidewire. The system may include a delivery shaft having a distal coupling feature adapted to releasably couple with a proximal coupling feature of the intracorporeal device. The delivery system may further include a hub through which the delivery shaft and guidewire are passed. The delivery shaft may be coupled to a feature, such as a knob, that enables manipulation of the delivery shaft to decouple the distal fixation feature from the proximal fixation feature of the intracorporeal device in order to deploy the intracorporeal device within a patient.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: January 19, 2021
    Assignee: PACESETTER, INC.
    Inventors: Tracee Eidenschink, Jin Woo Park, Jason A. White
  • Patent number: 10881306
    Abstract: A method is disclosed for continuously monitoring a blood pressure measurement using a sensor connected by a hydraulic link to an arterial catheter, the method includes determining the dynamic parameters of the link, analyzing the frequency content of the incident signal, detecting one of the following situations: (a) ability of the link to transmit the incident signal with a distortion below a threshold, (b) ability of the link to transmit the incident signal with a distortion above the threshold and possibility of correcting the measured signal, (c) inability of the link to transmit the incident signal with a distortion below the threshold and impossibility of correcting the measured signal, periodic application of a mechanical action to the tubing providing the hydraulic link.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: January 5, 2021
    Assignees: Universite Joseph Fourier—Grenoble 1, Automatisme et Informatique Industrielle
    Inventors: Francis Grimbert, Yves Lavault
  • Patent number: 10878963
    Abstract: Embodiments include a system for displays cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The computer system may determine at least one value of the blood flow characteristic within the patient's heart based on the model. The computer system may also display a report comprising a representation of at least one artery corresponding to at least a portion the model, and display one or more indicators of the value of the blood flow characteristic on a corresponding portion of the at least one artery.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: December 29, 2020
    Assignee: HeartFlow, Inc.
    Inventors: Charles A. Taylor, Gregory R. Hart
  • Patent number: 10849512
    Abstract: An intravascular system includes at least one pressure-sensing instrument sized and shaped for introduction into a vessel of a patient; a processing unit in communication with the pressure-sensing instrument, the processing unit configured to: obtain proximal pressure measurements for at least one cardiac cycle of the patient while the pressure-sensing instrument is positioned proximal of a stenosis of the vessel; obtain distal pressure measurements while the pressure-sensing instrument is positioned distal of the stenosis; select a diagnostic window within a cardiac cycle by identifying a change in sign of a slope associated with the proximal and/or distal pressure measurements, wherein the diagnostic window encompasses only a portion of the cardiac cycle of the patient; calculate a pressure ratio between the distal and proximal obtained during the diagnostic window; and output the calculated pressure ratio to a display device in communication with the processing unit.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: December 1, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Jinhyoung Park, Fergus Merritt
  • Patent number: 10849511
    Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. The methods can include introducing instruments into the vessel of a patient and obtaining proximal and distal pressure measurements of a stenosis of the vessel, calculating a pressure ratio based on the obtained proximal and distal pressure measurements, applying a correlation factor to the calculated pressure ratio to produce a predicted diagnostic pressure ratio, and displaying the predicted diagnostic pressure ratio to a user.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: December 1, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Andrew Tochterman, Fergus Merritt
  • Patent number: 10835670
    Abstract: Systems and methods for modulating delivery of a fluid medium to a selected site within a patient's body are described. A system includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a diversion reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe. The flow diverter assembly simultaneously increases fluid medium flow resistance with increasing pressure level of the fluid medium passing into the flow diverter assembly.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: November 17, 2020
    Assignee: Osprey Medical, Inc.
    Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
  • Patent number: 10820921
    Abstract: Dual-access site catheter systems with a blade or scoring functionality entering through a first access site and a balloon functionality for manipulating or driving the blade or scoring functionality through a different site. The blade or scoring functionality also sometimes provides needle or fluid delivery functionality to an atherosclerotic lesion.
    Type: Grant
    Filed: December 30, 2017
    Date of Patent: November 3, 2020
    Assignee: C.R. BARD, INC.
    Inventors: Michael Randall, Chad Van Liere, Andrzej J Chanduszko
  • Patent number: 10772565
    Abstract: The delivery system may include, for example, an outer catheter having a distal tip and an inner support member, such as an inner catheter, disposed within the outer catheter. The inner support member includes an anchor member adjacent a distal tip of the inner support member and a support portion axially inward of the anchor member. The support portion is configured for supporting an implantable device thereon. A diameter of the anchor member corresponds to a diameter of a portion of a vessel in which the anchor member is to be disposed. The anchor member is configured to be lodged in the portion of the vessel to locate an intended position of the anchor member and to prevent movement of the inner support member relative to the vessel during release of the implantable device.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: September 15, 2020
    Assignee: Ohio State Innovation Foundation
    Inventor: Rami Kahwash
  • Patent number: 10743774
    Abstract: One method for assessing a vessel can include obtaining a set of first location pressure measurements at a first location in the vessel over a first time period and a set of second location pressure measurements at a second location in the vessel over the first time period. This method can further include identifying a first leading characteristic associated with one or more pressure measurements in the set of first location pressure measurements, a second leading characteristic associated with one or more pressure measurements in the set of second location pressure measurements, a first trailing characteristic associated with one or more pressure measurements in the set of first location pressure measurements, and a second trailing characteristic associated with one or more pressure measurements in the set of second location pressure measurements. And, this method can include calculating a pressure ratio using pressure measurements between the identified characteristics.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: August 18, 2020
    Assignee: ACIST MEDICAL SYSTEMS, INC.
    Inventors: Jung W. Suh, Todd Suchecki, Thomas M. Snyder, Robert F. Wilson
  • Patent number: 10722629
    Abstract: A device for providing resuscitation or suspended state through redistribution of cardiac output to increase supply to the brain and heart for a patient. The device comprises an electrically controllable redistribution component in the form of a catheter, attachable to the patient and configured to interact with the patient to provide redistribution of the cardiac output to increase supply to the brain and heart, the redistribution component following a predefined reaction pattern based on an electrical signal, and computer configured to: receive a patient data which identifies physiological and/or anatomical characteristics of the patient; and provide the electrical signal for the redistribution component based on the patient data or a standard response. The device also comprises means for detection of blood vessels and motorized means for introduction of the catheter into an artery.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: July 28, 2020
    Assignee: Neurescue Aps
    Inventor: Habib Frost
  • Patent number: 10687794
    Abstract: A kit for implantation of an implantable medical device (IMD) comprises an elongated outer shaft, a tether, and an elongated inner shaft. The IMD comprises a fixation element comprising a looped portion. The outer shaft is sized to traverse a vasculature of the patient and defines a longitudinal lumen and a port in fluid communication with the lumen and located proximal a distal end of the outer shaft. A first portion of the tether is configured to pass through the lumen. A second portion of the tether is configured to exit the lumen through the port and pass through the looped portion of the fixation element of the IMD outside of the outer shaft. A third portion of the tether defines a looped portion of the tether. A portion of the inner shaft is configured to pass through the lumen and to pass through the looped portion of the tether.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: June 23, 2020
    Assignee: Medtronic, Inc.
    Inventors: Tomas K. Kelly, Paula McDonnell, James M. Keaveney, Jeffrey Madden
  • Patent number: 10646127
    Abstract: A blood flow analysis device includes a blood vessel region extraction unit that extracts a blood vessel region from a three-dimensional medical image of a subject including a blood vessel, and a blood flow simulation unit that obtains a line resistance by multiplying a resistance value corresponding to a branch blood vessel branching out of the blood vessel region by a surface area of each of preset sections into which the blood vessel region is divided in an extension direction, generates a vascular network model by applying the line resistance to each node of a surface of the blood vessel region, and performs simulation of a blood flow by using the vascular network model.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: May 12, 2020
    Assignee: FUJIFILM Corporation
    Inventors: Sho Onozawa, Takeshi Unemura, Hirotaka Ito
  • Patent number: 10646122
    Abstract: A distal shaft for measuring pressure distally of a stenosis includes a housing, a pressure sensor, a cover, a tip, and an aperture. The pressure sensor is mounted in the housing. The cover is coupled to the housing and covers the pressure sensor. The tip is coupled to a distal end of the housing. The aperture is disposed through the tip and/or cover. The aperture is configured to allow blood flow to the pressure sensor. The cover further includes a coupling mechanism or coupling that couples the cover to the housing. The coupling mechanism may be a snap-fit mechanism, a friction-fit mechanism, and/or an adhesive.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: May 12, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventors: Gerry McCaffrey, Sean Ward
  • Patent number: 10624697
    Abstract: A microwave ablation catheter assembly is provided. A coaxial cable configured to connect to a microwave energy source at its proximal end and at its distal end to a distal radiating section. The coaxial cable includes inner and outer conductors and a dielectric positioned therebetween. An extended working channel is configured to receive the coaxial cable for positioning the coaxial cable adjacent target tissue. At least a portion of an inner surface of the extended working channel is electrically conductive. The electrically conductive inner surface of the extended working channel may function as a balun to maintain a balanced signal between the inner and outer conductors of the coaxial cable when the distal radiating section of the coaxial cable is energized.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: April 21, 2020
    Assignee: COVIDIEN LP
    Inventor: William J. Dickhans
  • Patent number: 10610085
    Abstract: An interventional instrument, system and method include an elongated flexible member (100) having one or more segmented sections (101) disposed longitudinally. An optical fiber (104) is disposed internally in the flexible member. A plurality of optical sensors (102) are coupled to the optical fiber and distributed along a length of the flexible member such that the optical sensors are positioned to monitor parameters simultaneously at different positions or at different data sources along the flexible member to provide distributed sensing.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: April 7, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Raymond Chan, Maya Ella Barley, Adrien Emmanuel Desjardins, Guy Shechter, Gert 'T Hooft
  • Patent number: 10610181
    Abstract: Robust calcification tracking is provided in fluoroscopic imagery. A patient with an inserted catheter is scanned over time. A processor detects the catheter in the patient from the scanned image data. The processor tracks the movement of the catheter. The processor also detects a structure represented in the data. The structure is detected as a function of movement with a catheter. The processor tracks the movement of the structure using sampling based on a previous location of the structure in the patient. The processor may output an image of the structure.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: April 7, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Terrence Chen, Sarfaraz Hussein, Matthias John, Vivek Kumar Singh
  • Patent number: 10595765
    Abstract: A pressure measuring system, including a tube system having at least one first device for measuring pressure in a fluid. The at least one first device includes a coupling element, at least one pressure transducer and at least one measuring chamber, which can be filled with a fluid. Between the first device and the feed of the fluid, the tube system has a second device for regulating a fluid flow, the second device having a tube section through which fluid can flow and at least one tube clamp, which can be set in the regulation positions open, closed and perfused.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: March 24, 2020
    Assignee: MEDICAL MEASURMENT SYSTEMS B.V.
    Inventors: Michael Gondy Jensen, Jens Witte, David Van Gorkom, Kristine Larsen
  • Patent number: 10571354
    Abstract: A test chamber is used within a system for testing microelectromechanical systems (MEMS) pressure sensors. The system includes a processor, two air tanks pressurized to different air pressures, a high speed switch mechanism, and the test chamber. The test chamber houses a MEMS pressure sensor to be tested, a control pressure sensor, and a temperature sensor. The MEMS pressure sensor and the control pressure sensor are located in a cavity within the test chamber. The cavity is of minimal size and has a domed inner surface. A response time of the MEMS pressure sensor within the cavity can be characterized by utilizing the system and subjecting the MEMS pressure sensor to a pressure stimulus pulse produced by switching between the two air tanks.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: February 25, 2020
    Assignee: NXP USA, Inc.
    Inventors: Philippe Garre, Silvia Garre, William DeWitt McWhorter, Larry Dale Metzler
  • Patent number: 10561786
    Abstract: A valve is disclosed that has a body with an inlet, an outlet, and a needleless access port coupled to the body. The access port has an interior space and is configured to be actuated by a needleless connector. The inlet is selectively coupled to the outlet through the interior space such that fluid entering the inlet entirely flows through the interior space to the outlet.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: February 18, 2020
    Assignee: CareFusion 303, Inc.
    Inventors: George Mansour, Christopher Zollinger