Measuring Pressure In Heart Or Blood Vessel Patents (Class 600/485)
  • Patent number: 12232852
    Abstract: The present technology relates to vascular access devices, systems, and methods configured to monitor a patient's health. In some embodiments, the vascular access device may include a sensing element, and the system of the present technology may be configured to obtain physiological measurements of the patient via the sensing element, determine at least one physiological parameter based on the physiological measurement, compare the at least one physiological parameter to a predetermined threshold, and, based on the comparison, provide an indication of the patient's health.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: February 25, 2025
    Assignee: Verid Health Inc.
    Inventors: James D. Mitchell, Theodore C. Johnson, Andrew Thoreson
  • Patent number: 12233241
    Abstract: Methods and systems to validated physiologic waveform reliability and uses thereof are provided. A number of embodiments describe methods to validate waveform reliability, including blood pressure waveforms, electrocardiographic waveforms, and/or any other physiological measurement producing a continuous waveform. Certain embodiments output reliability measurements to closed loop systems that can control infusion rates of cardioactive drugs or other fluids in order to regulate blood pressure, cardiac rate, cardiac contractility, and/or vasomotor tone. Further embodiments allow for waveform evaluators to validate waveform reliability based on at least one waveform feature using data collected from clinical monitors using machine learning algorithms.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: February 25, 2025
    Assignee: The Regents of the University of California
    Inventors: Joseph B. Rinehart, Michael Ma
  • Patent number: 12237084
    Abstract: A method for mitigating the spread of infectious diseases among dialysis patients is provided. The method comprises: receiving, by a prediction system and from a medical facility, individual treatment data indicating dialysis treatment information associated with a patient undergoing dialysis treatment; receiving, by the prediction system and from a blood testing laboratory, individual lab data indicating blood analysis information associated with the patient; determining, by the prediction system, disease analysis results for the patient based on inputting the individual treatment data and the individual lab data into a disease prediction machine learning (ML) model, wherein the disease analysis results indicate a likelihood of the patient being infected with a contagious disease; and providing, by the prediction system and to the medical facility, instructions indicating one or more responsive actions based on the disease analysis results.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: February 25, 2025
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Caitlin Kelly Monaghan, Peter Kotanko, John Larkin, Jeffrey Hymes, Kathleen Belmonte, Len Usvyat, Ines A. Dahne-Steuber, Franklin W. Maddux
  • Patent number: 12226226
    Abstract: Methods and systems for seamless adjustment of treatment are disclosed. A determination is made as to whether to intervene with a patient's treatment. Implanted device memory data is acquired over a pre-specified time period. Risk status is determined from the device memory data. Another external device memory data is acquired over a pre-specified time period. A determination is made as to whether to adjust treatment of the patient in response to the risk status, the data acquired from the implanted device memory and the external device memory data.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: February 18, 2025
    Assignee: Medtronic, Inc.
    Inventors: Vinod Sharma, Eduardo N. Warman, Shantanu Sarkar, Tommy D. Bennett, Lindsay M. Streeter, Jennifer K. Bravinder
  • Patent number: 12222239
    Abstract: A calibration apparatus for calibrating a laser Doppler vibrometer includes: a frequency shifter stage that: receives, from the laser Doppler vibrometer, primary laser light; produces frequency shifted light; communicates the frequency shifted light to a reflector; receives frequency shifted light reflected by the reflector; produces secondary light; and communicates the secondary light to the laser Doppler vibrometer, such that the laser Doppler vibrometer receives the secondary light from the frequency shifter stage and produces a synthetic velocity shift from the secondary light; and the reflector that receives and reflects the frequency shifted light back to the frequency shifter stage.
    Type: Grant
    Filed: January 11, 2024
    Date of Patent: February 11, 2025
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Michael Gaitan, Jon Clement Geist, Benjamin James Reschovsky, Akobuije Douglas Eziani Chijioke
  • Patent number: 12186059
    Abstract: An adaptive bio-signal feature combining apparatus includes: a feature extractor configured to extract first feature values and second feature values from a bio-signal of an object; a stable interval determiner configured to determine at least one stable interval in the bio-signal; a statistical variable calculator configured to calculate a statistical variable value of a first feature and a statistical variable value of a second feature for each of the at least one stable interval based on the first and second feature values extracted from the at least one stable interval; and a feature combiner configured to calculate an integrated combining coefficient that is used to combine the first feature and the second feature, based on the statistical variable value of the first feature and the statistical variable value of the second feature.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: January 7, 2025
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Soon Park, Ui Kun Kwon, Dae Geun Jang, Young Soo Kim
  • Patent number: 12179009
    Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.
    Type: Grant
    Filed: May 2, 2022
    Date of Patent: December 31, 2024
    Assignees: Abiomed, Inc., Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Ahmad El Katerji, Qing Tan, Christian Moyer, Alexander Ship, Sonya Sanat Bhavsar, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller
  • Patent number: 12156885
    Abstract: The disclosure provides methods and compositions for treating heart conditions. In particular, the disclosure provides compositions comprising lithium, or a salt thereof, either alone or in combination with at least one additional anti-arrhythmia agent, and methods for treating heart conditions using such compositions.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: December 3, 2024
    Inventor: Catherine Lueninghoener
  • Patent number: 12097330
    Abstract: Disclosed is a massage apparatus including a processor configurable to receive a first dataset associated with a physiological parameter of an individual to derive a first emotional indication of the individual; wherein the first emotional indication and the first dataset are configured as inputs to derive a second emotional indication of the individual.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: September 24, 2024
    Assignee: OSIM INTERNATIONAL PTE. LTD.
    Inventors: Kia Tong Tan, Gilbert Realuyo, Rui Zou, Kiran Buch
  • Patent number: 12097013
    Abstract: A pulse diagnosis measurement device comprises a sensing device, for sensing a blood pressure wave of an organism, to generate a pulse signal; a pulse-holding device, for applying a pressure on a pulse of the organism, wherein the pulse-holding device has an elasticity coefficient, the elasticity coefficient is corresponding to a frequency of a harmonic of the blood pressure wave, and the harmonic is an integer harmonic or a fractional harmonic; and a processing device, for generating pulse diagnosis information of the harmonic according to the pulse signal.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: September 24, 2024
    Assignee: Contemporary Han Cloud Co., Ltd
    Inventor: Yu-Cheng Kuo
  • Patent number: 12089958
    Abstract: The present invention provides a PHHM for the measurement of a subject's BP and, optionally, one or more other vital signs, comprising a housing located on a PHHCD or a hand-held component of a computing system; a blood flow occlusion means located in the housing such that, when the housing is located on the PHHCD or the hand-held component, an open surface of the blood flow occlusion means is available to be pressed against a body part of the subject or to have a body part of the subject pressed against it; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied to or by the open surface; a means for detecting the flow of blood in the body part of the subject when pressure is applied to or by the open surface; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the PHHCD or the computing system, wherein the processor of t
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: September 17, 2024
    Assignee: LMD IP, LLC
    Inventors: Christopher Elliott, Mark-Eric Jones, Mikhail Nagoga, Shady Gawad, Mark Bennett
  • Patent number: 12053306
    Abstract: An apparatus for estimating blood pressure is provided. According to one embodiment, the apparatus for estimating blood pressure may include a sensor configured to measure a bio-signal from a subject, and a processor configured to acquire, form the bio-signal, a first feature value associated with cardiac output (CO) and a second feature value associated with total peripheral resistance (TPR), determine whether a current mechanism of blood pressure change of the subject is a post-exercise hypotension mechanism based on the first feature value and the second feature value, and estimate blood pressure according to determination of whether the current mechanism is the post-exercise hypotension mechanism.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: August 6, 2024
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Soon Park, Ui Kun Kwon, Youn Ho Kim, Seung Keun Yoon, Dae Geun Jang
  • Patent number: 12048515
    Abstract: A device which provides a measure of the compliance of a vessel wall based on a change in pressure, which causes the vessel to distend. The device comprises a coil and capacitor, forming a tank circuit. The coil is expandable and positioned along a portion of the vessel so that when the portion of the vessel expands or contracts, the coil will also expand or contract, changing the area in side the coil. This change in area alters the coil inductance, and therefore the resonant frequency of the tank circuit, which can be detected externally.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: July 30, 2024
    Assignee: Epic Neuro, Inc.
    Inventors: James William Phillips, Robert Abrams
  • Patent number: 11998752
    Abstract: A wearable cardioverter defibrillator (WCD) system comprises a plurality of patient parameter electrodes and a plurality of defibrillator electrodes to contact a patient's skin when the WCD is delivering therapy to the patient, a processor to receive one or more patient parameters from the one or more patient parameter electrodes, an energy storage device to store a charge to provide electrical therapy to the patient via the plurality of defibrillator electrodes, and a non-invasive blood pressure (NIBP) monitor to obtain a blood pressure measurement of the patient and to provide the blood pressure measurement to the processor. The processor is to determine whether to provide electrical therapy to the patient based on the one or more patient parameters during an episode, and to obtain the blood pressure measurement from the NIBP monitor during the episode.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: June 4, 2024
    Assignee: West Affum Holdings DAC
    Inventors: Kenneth F. Cowan, Steven E. Sjoquist, Zoie R. Engman, Erick M. Roane, Laura M. Gustavson, Douglas K. Medema, Garrett M. Kotlarchik, Pamela Breske, Jonathan P. Niegowski, Joseph L. Sullivan, Robert R. Buchanan
  • Patent number: 11998709
    Abstract: A sheath assembly includes a first sheath, a second sheath, and an attachment mechanism. The first sheath includes a first sheath inner surface defining a first sheath lumen extending along a first sheath central longitudinal axis between a first sheath first end portion and a first sheath second end portion. The second sheath includes a second sheath inner surface defining a second sheath lumen extending along a second sheath longitudinal axis between a second sheath first end portion and a second sheath second end portion. The attachment mechanism couples the second sheath to the first sheath. The attachment mechanism includes an attachment mechanism step-up dilation. At least a portion of the attachment mechanism is asymmetrical, at the attachment mechanism step-up dilation, about the first sheath central longitudinal axis.
    Type: Grant
    Filed: July 6, 2022
    Date of Patent: June 4, 2024
    Assignee: EVOLUTIONMEDVENTURES LLC
    Inventors: Sameer Gafoor, Ahmed Elmouelhi
  • Patent number: 11974839
    Abstract: A circulatory dynamic measuring apparatus includes: an electrocardiogram acquiring section which is configured to acquire an electrocardiogram of a subject; a pulse wave acquiring section which is configured to acquire a poise wave of an upper arm of the subject; and a calculator which is configured to calculate information that relates to a cardiac function of the subject, and that is based on a pulse wave transmit time obtained from the electrocardiogram and the pulse wave.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: May 7, 2024
    Assignee: NIHON KOHDEN CORPORATION
    Inventors: Teiji Ukawa, Haruka Sato
  • Patent number: 11944417
    Abstract: The disclosure provides a wearing detection method, a wearable device, and a computer readable storage medium. The method includes: in response to determining that the wearable device is in a static state, emitting a plurality of first photoplethysmography (PPG) signals, and detecting a plurality of second PPG signals corresponding to the first PPG signals; obtaining a zero-crossing rate corresponding to the second PPG signals; and in response to determining that the zero-crossing rate of the second PPG signals is higher than a reference threshold, determining that the wearable device is in an unworn state.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: April 2, 2024
    Assignee: BOMDIC INC.
    Inventor: Yao Shiao
  • Patent number: 11925442
    Abstract: A system for measuring blood pressure information of a subject, and includes: an electrocardiogram detection unit for detecting an electrocardiogram of the subject; a pulse wave detection unit for detecting pulse waves of the subject; a first computation unit for computing a ventricular systolic phase pulse transit time on the basis of the R wave of the electrocardiogram waveform based on the potential detected by the electrocardiogram detection unit and the P wave of the pulse waveform detected by the pulse wave detection unit, and computing a ventricular diastolic phase pulse transit time on the basis of the T wave of the electrocardiogram waveform and the D wave of the pulse waveform.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 12, 2024
    Assignee: Arblet Inc.
    Inventor: Kosuke Shimizu
  • Patent number: 11918325
    Abstract: A system and method is disclosed for measurement of pulse wave velocity of a vessel. An intravascular device comprises a first and a second marker provided at different locations along the length of the intravascular device of which positions are localizable by a tracking apparatus. The intravascular device provides plurality of measurements along the length of the vessel, while the intravascular device is moved from a first position to a second position, corresponding to a first and a second time. At the second time the position of the first marker in the vessel corresponds to the position of the second marker at the first time. The pulse wave velocity value of the vessel is ascertained based on measurements associated for the first time and the second time from the plurality of measurements and based on the distance between the locations of the two markers along the length of the intravascular device.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: March 5, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Manfred Mueller, Arjen Van Der Horst
  • Patent number: 11911189
    Abstract: A method and apparatus for processing a biosignal is disclosed. The apparatus may extract reference points from a waveform of a biosignal, determine a pulse direction of the biosignal based on the extracted reference points, and determine a feature point of the biosignal based on a feature point determining method corresponding to the determined pulse direction of the biosignal.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: February 27, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Changmok Choi, Seungkeun Yoon, Ui Kun Kwon, Sang-Joon Kim
  • Patent number: 11896400
    Abstract: Provided are an electronic device for selectively storing blood pressure information and updating calibration data on the basis of the stored blood pressure information, and a control method. The electronic device comprises, a memory operably connected with the processor, wherein the memory can include instructions, during the execution thereof, for allowing the processor to, display a user interface on a display, allow the user interface to provide guidelines for measuring the blood pressure, receive first data from the motion sensor, receive second data from a PPG sensor, receive third data from the PPG sensor, determine the validity of the third data at least partially on basis of the first data and the second data, and display an indication on the user interface at least partially basis of the determined validity.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: February 13, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Sunghwan Cho, Jinho Kim, Seunghwan Shin, Junseok Oh, Inho Yun, Hongji Lee, Taehan Jeon
  • Patent number: 11883141
    Abstract: A biological information measurement apparatus includes: a pressure sensor including a pressure detecting element; a pressing mechanism which presses the pressure sensor against an artery in a living body; a press controller which controls a pressing force of the pressing mechanism; a blood flow sensor; a blood flow information measurer which measures blood flow information based on output of the blood flow sensor; a pressing force decider which decides a first pressing force based on blood flow information measured during a pressing force control time period when the pressing force is changed in one direction, and information of a pressure pulse wave detected during the pressing force control time period; and a record controller which records a pressure pulse wave detected in a first state where the pressing force is controlled to the first pressing force, and blood flow information measured in the first state.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: January 30, 2024
    Assignees: OMRON HEALTHCARE Co., Ltd., OSAKA UNIVERSITY
    Inventors: Yuki Kato, Shingo Yamashita, Toshihiko Ogura, Shunsuke Yoshimoto, Masataka Imura, Osamu Oshiro
  • Patent number: 11883230
    Abstract: A transcranial scanning device and method of use is disclosed. The transcranial scanning device is for identifying a neurologic-injury-mechanism and comprises a sensing wand comprising a transducer that produces and receives sound waves. The sensing wand is passed over a head of a patent with cerebral malaria, and sound waves reflect off of blood cells in blood vessels in the head of the patient creating an output sound wave responsive to a blood flow of the patient. The output sound wave is received by the transducer. An output screen coupled to the sensing wand, displays in real time an output waveform corresponding to the output sound wave, wherein the output waveform is indicative of one or more symptoms of cerebral malaria, and wherein said symptoms identify one or more neurologic-injury-mechanism occurring within the patient.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: January 30, 2024
    Assignee: The Research Institute at Nationwide Children's Hospital
    Inventor: Nicole Fortier O'Brien
  • Patent number: 11864912
    Abstract: The invention is related to a device to sense the pulse on a wrist of a subject and to arrive at the health status of the said subject by capturing the pulse in real time; analyzing the pulse based on time-frequency properties of the pulse signal and Vata, Pitta and Kaphahumors of the subject. The device reliably detects and captures noise free pulse characteristics of a subject at the appropriate locations of the subject's wrist with minimal positional error in a user friendly way with minimal reliance on the expertise of the person measuring the pulses. The device facilitates the analysis of the pulses and provides a comprehensive diagnostic system based on the pulse characteristics, visual features, responses of a subject to structured queries to arrive at the tridosha levels in a subject.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: January 9, 2024
    Assignee: ATREYA INNOVATIONS PRIVATE LIMITED
    Inventor: Aniruddha Jyeshtharaj Joshi
  • Patent number: 11850066
    Abstract: A system and method for measuring and monitoring blood pressure is provided. The system includes a wearable device and a tonometry device coupled to the wearable device. The Tonometry device is configured to compress a superficial temporal artery (STA] of a user. A sensor pad is attached to the wearable device adjacent the tonometry device. A blood pressure sensor is integrated within the sensor pad for continuous, unobtrusive blood pressure monitoring.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: December 26, 2023
    Assignee: The General Hospital Corporation
    Inventors: Quan Zhang, Yuanting Zhang
  • Patent number: 11844591
    Abstract: One aspect of the subject matter described in this disclosure can be implemented in a device capable of use in estimating blood pressure. The device includes one or more arterial sensors configured to obtain arterial measurements at two or more elevations. The device additionally includes one or more processors configured to determine one or more calibration parameters for a first blood pressure model based on the arterial measurements and a hydrostatic pressure difference between at least two of the elevations. The processors also are configured to determine a first blood pressure based on the first blood pressure model, the calibration parameters and the arterial measurements. The processors also are configured to determine a second blood pressure based in part on a second blood pressure model, one or more calibration parameters and the arterial measurements. The processors are further configured to provide a final blood pressure based on the first and second blood pressures.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: December 19, 2023
    Assignee: QUALCOMM Incorporated
    Inventors: David Boettcher Baek, Lars Lading
  • Patent number: 11844618
    Abstract: A system and method for cardiovascular monitoring and reporting are disclosed. The system (CV monitoring system) includes a data analysis system and an in-ear biosensor system that preferably includes left and right earbuds. The earbuds include infrasound/vibration sensors that detect biosignals from the individual including signals associated with cardiovascular activity (CV signals). The analysis system calculates cardiovascular function measurements (CV function measurements) based upon the CV signals. The CV monitoring system uses machine learning to predict blood pressure (BP) measurements of the individual based upon the CV signals and the calculated CV function measurements. In an embodiment, the CV monitoring system includes an EKG detection system that detects EKG signals associated with heart function.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: December 19, 2023
    Inventors: Anna Barnacka, Charles R Bridges, Siddharth Patel
  • Patent number: 11830624
    Abstract: The system for cardiovascular parameter data quality determination can include a user device and a computing system, wherein the user device can include one or more sensors, the computing system, and/or any suitable components. The computing system can optionally include a data quality module, a cardiovascular parameter module, a storage module, and/or any suitable modules. The method for cardiovascular parameter data quality determination can include acquiring data and determining a quality of the data. The method can optionally include processing the data, and/or determining a cardiovascular parameter, training a data quality module, any suitable steps.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: November 28, 2023
    Assignee: Riva Health, Inc.
    Inventors: Tuhin Sinha, Mark Mozolewski
  • Patent number: 11825206
    Abstract: Examples of the disclosure relate to at least apparatus, methods, and computer programs, configured to control capture of two images of an area, across which a pulse propagates, using different shutter scanning directions. Either the images are converted into pulse-phase maps of the area and a pulse-phase difference map obtained which identifies differences between the pulse-phase maps of the area, or a colour difference map is obtained which identifies differences between the two images and the colour difference map is converted into a pulse-phase difference map. A shutter-time difference map is obtained which identifies differences between capture times of corresponding locations in the two images. Using the shutter-time difference map, the pulse-phase difference map is corrected to obtain a map of pulse-phase changes which have occurred over a duration of a shutter scan.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: November 21, 2023
    Assignee: Nokia Technologies Oy
    Inventors: Christopher Wright, Harry Cronin, Phil Catton, William Schnabel
  • Patent number: 11813086
    Abstract: A measurement system includes: a sensor wire comprising an insertable portion configured to be inserted in a blood vessel of a patient's body; a sensor disposed at the insertable portion at a distal end of the sensor wire, wherein the sensor is configured to provide an output indicative of a temperature in the blood vessel of the patient's body, when inserted inside the blood vessel of the patient's body; and a transceiver unit configured to transfer information related to the output of the sensor to an external communication module using a frequency hopping technique. The transceiver unit comprises a housing adapted to be connected to a proximal end of the sensor wire and configured to remain external to the patient's body.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: November 14, 2023
    Assignee: ST. JUDE MEDICAL COORDINATION CENTER BVBA
    Inventors: Magnus Samuelsson, Sauli Tulkki
  • Patent number: 11800985
    Abstract: The present invention provides an electrocardiographic monitoring device comprising a device body configured to be attached to a user's chest; a plurality of electrodes provided on the device body; and a controller provided on the device body and connected to the electrodes in order to obtain the user's electrocardiographic signal waveforms. The electrocardiographic monitoring device of the invention can be applied in a blood pressure monitoring system for monitoring a user's blood pressure.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: October 31, 2023
    Assignees: BIV MEDICAL, LTD.
    Inventors: Shiming Lin, Shih-Wei Chiang, Cheng-Yan Guo, Tai-Cun Lin, Wei-Chih Huang, Chun-Nan Chen, Ya-Ting Chang
  • Patent number: 11793465
    Abstract: A display device includes: a display panel including a first area having a first light transmissivity and a second area having a second light transmissivity higher than the first light transmissivity; a pressure sensor overlapping the first area; a light emitter overlapping the second area; a light receiver overlapping the second area and spaced from the light emitter; and a processor to control the light emitter and the pressure sensor, and to output a blood pressure signal on a basis of a pressure sensing signal from the pressure sensor and a light sensing signal from the light receiver.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: October 24, 2023
    Assignee: Samsung Display Co., LTD.
    Inventors: Won-Ki Hong, Hee Seomoon, Hyeon Jun Lee
  • Patent number: 11786179
    Abstract: A bio-signal measuring apparatus includes: a substrate; a pulse wave measurer provided at the substrate and configured to measure pulse waves of a subject; and a pressure measurer provided at the substrate and configured to measure a contact pressure between the subject and the pulse wave measurer.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: October 17, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Mok Choi, Byung Hoon Ko, Young Soo Kim, Jong Wook Lee, Youn Ho Kim
  • Patent number: 11779228
    Abstract: A bio-signal measurement apparatus may include a first substrate and a second substrate, an optical sensor mounted in the first substrate, a force sensor disposed on or below the first substrate, and a separation structure interposed between the first substrate and the second substrate so as to prevent transmission of a force between the first substrate and the second substrate. An upper surface of the first substrate and an upper surface of the second substrate may be provided at the same level.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: October 10, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Byung Hoon Ko, Yong Joo Kwon, Young Soo Kim, Sang Yun Park, Jong Wook Lee, Chang Mok Choi, Jae Min Kang, Youn Ho Kim
  • Patent number: 11779230
    Abstract: Current oscillometric devices for monitoring central blood pressure (BP) maintain the cuff pressure at a constant level to acquire a pulse volume plethysmography (PVP) waveform and calibrate it to brachial BP levels estimated with population average methods. A physiologic method was developed to further advance central BP measurement. A patient-specific method was applied to estimate brachial BP levels from a cuff pressure waveform obtained during conventional deflation via a nonlinear arterial compliance model. A physiologically-inspired method was then employed to extract the PVP waveform from the same waveform via ensemble averaging and calibrate it to the brachial BP levels. A method based on a wave reflection model was thereafter employed to define a variable transfer function, which was applied to the calibrated waveform to derive central BP.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: October 10, 2023
    Assignee: Board of Trustees of Michigan State University
    Inventors: Ramakrishna Mukkamala, Keerthana Natarajan, Jin-Oh Hahn
  • Patent number: 11751814
    Abstract: An apparatus for estimating biological information of a user may include a light source configured to emit light to an object of the user; an image sensor comprising a pixel array, and configured to acquire successive image frames by detecting light scattered or reflected from the object of the user; and a processor configured to: select a predetermined number of pixel-rows from among pixel-rows of the image sensor, detect signal intensities in the predetermined number of pixel-rows for each image frame of the successive image frames, correct the signal intensities, combine the signal intensities for each image frame of the successive image frames based on correcting the signal intensities, acquire a photoplethysmogram (PPG) signal based on combining the signal intensities, and estimate the biological information of the user based on the PPG signal.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: September 12, 2023
    Assignees: SAMSUNG ELECTRONICS CO., LTD., POSTECH Research and Business Development Foundation
    Inventors: Young Soo Kim, Sung-Min Park, Youn Ho Kim, Vega Pradana Rachim, Sang Yun Park, JinHyeok Baek
  • Patent number: 11744476
    Abstract: A blood pressure measurement device may include one or more piezoelectric sensors (e.g., differential piezoelectric sensors) for detecting blood flow through a limb of a user as part of determining blood pressure measurements. The piezoelectric sensor(s) may additionally or alternatively be used to determine one or more biological parameters of users (e.g., a ballistocardiogram, a heart rate, a heart rate variability, and a pulse wave velocity). The blood pressure measurement device may additionally or alternatively include a capacitive sensor for determining a pressure applied to the limb of the user by the blood pressure measurement device and/or operational states of the blood pressure measurement devices (off-arm, on-arm, inflating, deflating, tightness, and the like).
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: September 5, 2023
    Assignee: Apple Inc.
    Inventors: Wegene H. Tadele, Makiko K. Brzezinski, Riley E. Brandt, Siddharth Nangia
  • Patent number: 11737723
    Abstract: The embodiments herein provide a system for calibration-free cuff-less evaluation of blood pressure. The system includes an ultrasound-based arterial compliance probes and a controller unit connected to the said probe. The ultrasound transducers are configured to measure the change in arterial dimensions, pulse wave velocity, and other character traits of an arterial segment over continuous cardiac cycle, which is then used to evaluate blood pressure parameters without any calibration procedure using dedicated mathematical models.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: August 29, 2023
    Assignee: HEALTHCARE TECHNOLOGY INNOVATION CENTER
    Inventors: Nabeel Pilaparambil Mashood, Jayaraj Joseph, Mohanasankar Sivaprakasam, Vangapandu Raj Kiran
  • Patent number: 11712168
    Abstract: The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: August 1, 2023
    Assignee: Vita-Course Technoloaies (Hainan) Co., Ltd.
    Inventors: Ying Lu, Chuanmin Wei, Heng Peng, Jiwei Zhao, Ziming Deng, Zijian Huang
  • Patent number: 11701092
    Abstract: A fully automated ultrasound apparatus includes a sensor or probe which can be initially manually attached to a side of the neck of a patient, an ultrasound interface to control the sensor and periodically acquire raw ultrasound data, a signal and image processing system to autonomously convert the raw ultrasound data into a measurement that is useful to physicians, and a display to relay the current measurements and measurement history to provide data trends. The sensor can include one or more ultrasound transducers built into a housing. A disposable component can serve to secure the sensor to the neck of the patient and to provide a coupling medium between the sensor and the skin of the patient.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: July 18, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Grant Kruger, Torben K. Becker, Nikhil Theyyunni, Ross Kessler, Bradley Plummer, Matthew Tafoya, Chelsea Tafoya, Steven E. Harte
  • Patent number: 11666233
    Abstract: A system and method for monitoring the blood pressure of a patient that allows for a device sensor to be recalibrated according to atmospheric pressure without removing the device sensor from inside the patient. This permits quickly monitoring the blood pressure of a patient if a re-zero is needed. The invention has a blood pressure monitor (BPM) that obtains an atmospheric pressure observation. The atmospheric pressure observation is adjusted and stored to memory as a zero value. The zero value is retrieved to recalibrate the system and method if a device sensor has been disconnected from and reconnected to the same or a different BPM, the patient has been moved such that the surroundings have been altered to make it necessary to recalibrate according to atmospheric pressure, and/or the device sensor has been connected to a different patient care monitor.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: June 6, 2023
    Assignee: Endophys Holdings, LLC
    Inventor: Phillip D. Purdy
  • Patent number: 11627884
    Abstract: [Subject] Non-invasive method for estimating blood pressure without a cuff and a device for the blood pressure estimation [Resolution means] Systolic blood pressure (EBP) is estimated according to EBP=?1·P1+?2·P2+?0 (?1, ?2, and ?0 are coefficients) where parameter P1, which is related to pulse transit time (PTT), and parameter P2, which is related to stroke volume based on pulse waves, are variables.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: April 18, 2023
    Assignee: Health Sensing Co., Ltd.
    Inventors: Masatomo Kanegae, Kyuichi Niizeki
  • Patent number: 11622693
    Abstract: Various examples are provided for non-contact vital sign acquisition. Information can be provided regarding vibrations of a target using a radar signal such as, e.g., non-contact vital sign measurement. Examples include estimation of heart rate, change in heart rate, respiration rate, and/or change in respiration rate, for a human or other animal. Implementations can produce one or both rates of vibration and/or change in one or both rates of vibration for a target other than an animal or human experiencing two vibrations at the same time, such as a motor, a vehicle incorporating a motor, or another physical object. Some implementations can estimate the respiration movement in the radar baseband output signal. The estimated respiration signal can then be subtracted from radar signals in the time domain and, optionally, can be further enhanced using digital signal processing techniques, to produce an estimate of the heartbeat pulses.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: April 11, 2023
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Jenshan Lin, Changyu Wei
  • Patent number: 11622692
    Abstract: A signal processing apparatus includes a memory configured to store instructions; and a processor configured to execute the instructions to obtain a signal; obtain a frequency band spectrum by applying a Fast Fourier Transform (FFT) to the obtained signal; and remove noise from the obtained spectrum by applying a first filter and a second filter, which are different from each other, to the obtained frequency band spectrum.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: April 11, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Mok Choi, Dae Geun Jang
  • Patent number: 11617594
    Abstract: An endoscopic instrument for use with a trocar, said endoscopic instrument comprising an elongate shaft body having a proximal end and a distal end; an end effector assembly at said distal end operable by manipulation of actuator mechanism at said proximal end; a substrate core having a first surface and a second surface; at least one sensing element on said first surface, said at least one sensing element located adjacent to said distal end; an electronics module for receiving sensed signals from said at least one sensing element, said electronics module located adjacent to said proximal end; a first conductive layer residing on said first surface, said first conductive layer having first solder mask coated thereon; a second conductive layer residing on said second surface, second conductive layer having a second solder mask coated thereon, and wherein said second conductive layer coupled to said at least one sensing element relays said sensed signals from said at least one sensing element to said electronic
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: April 4, 2023
    Assignee: Forcen Inc.
    Inventors: Robert Brooks, Justin Wee, Justin Gerstle, Thomas Looi, James Drake
  • Patent number: 11617563
    Abstract: The present invention relates to a method and system for determining a central pulse wave velocity in a pregnant woman. The method comprises receiving an indication of a measurement of a length of a human aortic path outside the body to provide an aortic length, arranging a sound transducer at the position of the anatomical projection of the uterine artery, identifying the opening of the maternal aortic valve with measurement from the sound transducer as a first time, and the pulse wave arrival time at the uterine artery with measurements from the sound transducer as a second time, determining the central transit time based on the difference between the second time and the first time, and calculating the central pulse wave velocity based on the aortic length and the central transit time.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: April 4, 2023
    Assignee: VIEWCARE TECHNOLOGIES 1 APS
    Inventors: Diana Kjær Thing Riknagel, Johannes Jan Struijk
  • Patent number: 11612357
    Abstract: A blood pressure monitor cuff is formed by stacking an outer circumferential layer arranged on a side opposite to that of a measurement site and a fluid bladder arranged on the measurement site side. The outer circumferential layer and the fluid bladder are formed of an elastomer material. Two edge portions in a lengthwise direction of the outer circumferential layer protrude in a thickness direction toward the measurement site. The fluid bladder includes a base layer that opposes the outer circumferential layer and a top layer overlapping with the base layer, and the edge portions of the base layer and the top layer are welded together forming a bladder shape. Additional sheets are welded in the thickness direction to the welded edge portions of the top layer and the base layer. The fluid bladder is arranged between the two edge portions of the outer circumferential layer in the width direction.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: March 28, 2023
    Assignee: OMRON HEALTHCARE Co., Ltd.
    Inventors: Ryosuke Doi, Chisato Tawara, Takayuki Matsuoka, Yuichiro Arima, Yoshihide Tokko, Minoru Taniguchi, Yuma Adachi, Masayuki Fukutsuka
  • Patent number: 11596360
    Abstract: A system for collecting data for assessment of cardiovascular function includes a plurality of monitoring devices coupled to different respective body parts. Each monitoring device is configured to measure a respective signal at the respective body part in response to cardiovascular activity. The respective signal includes a cardiovascular component attributable to the cardiovascular activity and an artifact component not attributable to the cardiovascular activity. When the monitoring devices measure the respective signals simultaneously over a same time period, the cardiovascular components are correlated, and the artifact components are not correlated.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: March 7, 2023
    Assignee: Verily Life Sciences LLC
    Inventors: Andrew Homyk, Jason Donald Thompson
  • Patent number: 11589758
    Abstract: Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: February 28, 2023
    Assignee: Fitbit, Inc.
    Inventors: Alexandros A. Pantelopoulos, Thomas Samuel Elliot, Logan Niehaus
  • Patent number: 11574741
    Abstract: The systems and methods described herein determine metrics of cardiac or vascular performance, such as cardiac output, and can use the metrics to determine appropriate levels of mechanical circulatory support to be provided to the patient. The systems and methods described determine cardiac performance by determining aortic pressure measurements (or other physiologic measurements) within a single heartbeat or across multiple heartbeats and using such measurements in conjunction with flow estimations or flow measurements made during the single heartbeat or multiple heartbeats to determine the cardiac performance, including determining the cardiac output. By utilizing a mechanical circulatory support system placed within the vasculature, the need to place a separate measurement device within a patient is reduced or eliminated. The system and methods described herein may characterize cardiac performance without altering the operation of the heart pump (e.g., without increasing or decreasing pump speed).
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: February 7, 2023
    Assignees: Abiomed, Inc., Massachusetts Institute of Technology, The Brigham and Women's Hospital Inc.
    Inventors: Qing Tan, Ahmad El Katerji, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller, Sonya Sanat Bhavsar