Qualitative Or Quantitative Analysis Of Breath Component Patents (Class 600/532)
  • Patent number: 11448640
    Abstract: A gas analyzer for measuring a respiratory gas component includes an emitter that transmits infrared (IR) radiation through a measurement chamber containing respiration gas, and at least one IR detector configured to receive at least a portion of the IR radiation transmitted through the measurement chamber and to generate radiation measurement data based on the received IR radiation. A light source is configured to emit light onto a color indicator, wherein the color indicator is one of a predefined set of colors. A color detector is configured to detect light reflected by a color indicator so as to identify color information. The controllers configured to determine a respiratory gas component concentration within the measurement chamber based on the color information and the radiation measurement data.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: September 20, 2022
    Assignee: GE Precision Healthcare LLC
    Inventor: Mika Harri Juhani Hietala
  • Patent number: 11439321
    Abstract: A medical monitoring system for identifying an end-exhalation carbon dioxide value of enhanced clinical utility is described herein. The medical monitoring system can include a capnometer for generating an output corresponding to a time-series of exhaled carbon dioxide values from a patient during an exhalation and a processor programmed to analyze the exhalation. In some examples, the processor can also be programmed to identify a peak carbon dioxide value at an end of the exhalation, determine if the peak carbon dioxide value may have been higher if the exhalation had been prolonged, and provide an output responsive to said determination.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: September 13, 2022
    Inventor: Lawrence A. Lynn
  • Patent number: 11441833
    Abstract: A cold air supply device is applied to an entrance refrigerator. The cold air supply device includes a thermoelectric element forming a heat absorbing surface and a heat generating surface, a cold sink in contact with the heat absorbing surface, a heat absorption fan disposed above the cold sink, a heat sink in contact with the heat generating surface, a heat dissipation fan disposed below the heat sink, and an insulation material disposed between the cold sink and the heat sink to block heat transfer. The cold sink includes a sink body, and a plurality of heat exchange fins arranged on the upper surface of the sink body. Absorption pads are provided on both side edges of the sink body to absorb condensed water generated on the surface of the cold sink.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: September 13, 2022
    Assignee: LG ELECTRONICS INC.
    Inventors: Minkyu Oh, Insun Yeo, Kyukwan Choi, Yezo Yun, Yanghwan No
  • Patent number: 11427083
    Abstract: A method and a system of deploying an ignition interlock device (IID). The method comprises receiving a time series of breath alcohol content (BrAC) measurements that are unitarily sourced from a pre-identified user, each BrAC measurement of the time series including an alveolar breath component and an interferent breath component; estimating a dissipation rate of alcohol attributable to the pre-identified user in accordance with the time series of BrAC measurements; determining, responsive to estimating the dissipation rate of alcohol, at least a subset of the BrAC measurements as being based on the alveolar breath component but not the interferent breath component; and performing one of triggering and not triggering the IID into a lockout state based on the at least a subset of the BrAC measurements.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: August 30, 2022
    Assignee: Consumer Safety Technology, LLC
    Inventors: Amanda Renee Mallinger, Jennifer Ringgenberg, Usha Rani Chintala, Douglas Robert Bruce, Sujitha Chandra Mohan
  • Patent number: 11415440
    Abstract: A flow sensor sub-assembly for sensing flow of a fluidic medicament is disclosed. The flow sensor sub-assembly includes a first spring contact and a second spring contact. The spring contacts are secured to a base that has a circuit for conducting an electrical signal to and from the spring contacts to a microprocessor. The first spring contact is in electrical communication with a first piezo element and the second spring contact is in electrical communication with a second piezo element. The first spring contact has a first contact force against the first piezo element and the second spring contact has a second contact force against the second piezo element, and the first and second contact forces are equivalent. A circuit board for interfacing to a flow sensor having a plurality of piezo elements for transmitting a flow signal indicative of flow of fluidic medicament is also disclosed.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: August 16, 2022
    Assignee: CRISI Medical Systems, Inc.
    Inventors: Shawn Wayne DeKalb, Mark Raptis
  • Patent number: 11399919
    Abstract: The invention relates to a sensor (1) for fastening to a multi-bracket appliance for the upper jaw (2), to a multi-bracket appliance for the lower jaw (3), to an aligner for the upper jaw (2?) and/or to an aligner for the lower jaw (3?), in order to measure the time span during which a force is applied to a pressure, tension and/or shear-force sensor (11) of the sensor (1), whereby the wearing duration of orthodontic elastics (4) for multi-bracket appliances (2, 3) and/or aligners (2?, 3?) can be monitored, the sensor (1) being a sensor that is independent of the multi-bracket appliance (2, 3) and the brackets (23) and including a timer, a microcontroller having a data memory, and an elastic holder (16) and/or elastic guide (17). The invention further relates to a system (5) for monitoring the wearing duration of orthodontic elastics, including the sensor (1), a multi-bracket apparatus or an aligner for the upper jaw (2, 2?) and the lower jaw (3, 3?), an elastic (4) and an external reading device.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: August 2, 2022
    Assignee: OTMAR KRONENBERG AG
    Inventor: Otmar Kronenberg
  • Patent number: 11375950
    Abstract: Some embodiments are directed to a self-contained breathing mask for measuring and monitoring the breath of a human subject. The mask may be lightweight, self-contained, and physically untethered to any test or measurement equipment, providing the subject full mobility, and allowing him/her to perform almost any daily activity during use. The mask may include integrated sensors for measuring properties of the subject's breath, over any length of time, providing respiratory information like breath count, rate and volume, oxygen consumption, and carbon dioxide production, as well as various biometric information.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: July 5, 2022
    Assignee: Calibre Biometrics Inc.
    Inventor: Udi E. Meirav
  • Patent number: 11331004
    Abstract: Methods and systems are described to obtain and analyze one or more gas samples from the breath of a person, and organizing the samples in a sample registry for subsequent analysis. This technique solves the various problems that are associated with targeting an individual breath for analysis, and allows for additional versatility and options in the analysis process.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: May 17, 2022
    Assignee: CAPNIA, INC.
    Inventors: Elvir Causevic, Anthony D. Wondka, Anish Bhatnagar
  • Patent number: 11330984
    Abstract: A sensing system includes a sensor including a flexible substrate and a graphene oxide sensing element deposited on the flexible substrate. The graphene oxide sensing element has first and second sides. First and second electrical connectors coupled to the first and second sides of the graphene oxide sensing element, respectively. A power source is coupled to the first and second electrical connectors of the sensor and is adapted to apply a constant voltage to the sensor. The sensing system also includes a measurement element measuring a current in the graphene oxide sensing element due to the constant voltage and a calculation element calculating an electrical resistance of the graphene oxide sensing element based on the electrical current and the constant voltage and calculating a condition at a location of the sensor based on a relationship between the electrical resistance and the condition for the graphene oxide sensing element.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: May 17, 2022
    Assignees: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY, FLEXTRAPOWER, INC.
    Inventors: Linh Tung Le, Trung Thanh Dinh-Trong, Woo Young Lee, Eric Peter Boon, Nguyen An Nguyen
  • Patent number: 11320419
    Abstract: A method for sampling breath gas, includes collecting a first breath sample in a first bag. The first breath sample is an initial part of expired gas expired after inspiration. Additionally, the method includes collecting a second breath sample in a second bag. The second breath sample is a latter part of the expired gas. The method includes subtracting first mass spectral data obtained by mass spectroscopy of the first breath sample collected in the first bag from second mass spectral data obtained by mass spectroscopy of the second breath sample collected in the second bag.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: May 3, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Akihiro Horibe, Kuniaki Sueoka, Toru Aihara
  • Patent number: 11304684
    Abstract: A device for collecting exhalation gas and aiding measurement of a trace component in the exhalation gas and the usage method thereof are disclosed. The device comprises an alveolar air bag for storing alveolar air collected from the breath of a subject, a cavity channel air bag for storing cavity channel air from the subject, a three-way pipe, and a mouthpiece. The three-way pipe comprises a first branch pipe, second branch pipe, and third branch pipe communicating with each other. The first branch pipe and the second branch pipe respectively extend in opposing directions along the same axis. The third branch pipe extends along a radial direction of the first branch pipe and the second branch pipe. The mouthpiece communicates with the first branch pipe. An air hole of the cavity channel air bag communicates with the second branch pipe.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 19, 2022
    Assignee: Shenzhen Seekya Bio-Sci & Tech Co., Ltd.
    Inventors: Yongjian Ma, Yongqiang Ji, Guoliang Zhu
  • Patent number: 11293802
    Abstract: Techniques, devices and methods for discriminating a target from a background material without optimizing directly on the target are provided. The devices and methods can generate pass bands of single or multiple wavelengths of variable shape and intensity, and can also select and control the shape of the pass band profiles to improve the detection of targets of interest.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: April 5, 2022
    Assignee: ChemImage Corporation
    Inventors: Alyssa Zrimsek, Heather Gomer, Shawna Tazik
  • Patent number: 11280726
    Abstract: An assembly and a method for measuring a gas concentration by means of absorption spectroscopy, in particular for capnometric measurement of the proportion of CO2 in breathing air in which IR light from a thermal light source is guided through a measuring cell with a gas mixture to be analyzed, and the concentration of the gas to be measured that is contained in the gas mixture is determined by measuring an attenuation of the light introduced into the measuring cell caused by absorption by the gas to be measured. The thermal light source is designed as an encapsulated micro-incandescent lamp with a light-generating coil.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: March 22, 2022
    Assignee: SENSATRONIC GMBH
    Inventors: Martin Degner, Hartmut Ewald
  • Patent number: 11259716
    Abstract: A respiration monitoring system has deformation transducers on a flexible substrate arranged to adhere to a patient's torso. A processor receives signals in channels from the transducers and processes them to eliminate, reduce or compensate for noise arising from patient motion artefacts, to provide an output representative of respiration. The transducers have a size and a mutual location on the substrate so that a first transducer can overlie at least part of the 10th rib and a second transducer can overlie at least part of the 11th rib or the abdomen, and the processor processes data from the first transducer as being primarily representative of rib distending respiration and from the second transducer as being primarily representative of either diaphragm respiration or patient motion artefacts.
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: March 1, 2022
    Assignee: PMD DEVICE SOLUTIONS LIMITED
    Inventors: Myles Murray, Stephen Cusack, Christopher Kinsella
  • Patent number: 11226305
    Abstract: Use: detecting the presence of small concentrations of target gases.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: January 18, 2022
    Assignee: Printeltech LLC
    Inventors: Alexey Sergeevich Sizov, Daniil Sergeevich Anisimov, Askold Albertovich Trul, Victoriya Petrovna Chekusova, Aleksandr Anatolevich Permyakov, Mikhail Yurevich Yablokov, Aleksey Andreevich Vasilev, Elena Valerievna Agina, Sergey Anatolevich Ponomarenko
  • Patent number: 11221295
    Abstract: Apparatuses and methods are provided for quantifying an analyte in a gas or liquid phase. A light source with an emission spectrum overlapping an absorption of the analyte, and a pair of reflective mirrors located on an optical axis to form an optical cavity can be included. An off-axis photon detector can be configured as a fluorescence detector and located off the cavity axis and arranged to provide a first signal in response to fluorescence within the cavity. An axial photon detector can be located axially, and external, to the cavity and arranged to provide a second signal. The portion of the apparatus including the light source, the cavity, and the axial photon detector can be configured with a cavity-enhanced absorption spectrometer, and the portion of the apparatus including the off-axis photon detector can be configured with a cavity-enhanced laser-induced fluorescence (CELIF) spectrophotometer.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: January 11, 2022
    Assignee: UNIVERSITY OF DURHAM
    Inventors: David Carty, Eckart Wrede, Nils Hendrik Nahler
  • Patent number: 11191450
    Abstract: Apparatus for quantifying the amount of re-breathing due to bedding materials. The re-breathing analyzer applies heated air to the material under test through an exhaust port in a probe and receives return air from an intake port in the probe. The exhaust and intake ports are placed to engage the material under test when the probe is in contact with the material. In one embodiment, the probe has a surface that is exposed through a top surface of a housing for the analyzer whereby the material under test is placed on the top surface for testing. The analyzer includes a differential temperature measuring instrument that determines the temperature of the return air, where an increase of the temperature of the return air above the temperature of the ambient air indicates the presence and quantity of re-breathing due to the material under test.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: December 7, 2021
    Inventor: Michael David Leshner
  • Patent number: 11195433
    Abstract: The present disclosure provides a system that quantitatively tracks an individual's diet and exercise using smart devices (phones, watches, and other wearables). Unlike existing programs, which work in energy units (calories), the present system works in mass units (grams) and satisfies the fundamental physics law of conservation of mass. Food ingested is tracked as well as exercise in order to place the user on a quantitative, custom diet that safely and effectively results in weight loss. In addition to rigorously treating the problem of weight loss by addressing the physics that underlies diet and exercise, the system empirically learns about the user over time such that performance may be optimized.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: December 7, 2021
    Assignee: Mindful Projects, LLC
    Inventor: Justin Crepp
  • Patent number: 11179044
    Abstract: A method of identifying alveolar ventilation (VA) in a subject, the method comprising: (1) using a breathing circuit which, at exhalation, keeps exhaled gas separate from inhaled gas and at inhalation, when a first gas set (FGS) flow is less than the subject's minute ventilation (VE), results in a subject inhaling FGS first and then a second gas set (SGS), for the balance of inhalation; (2) setting the FGS flow at a rate greater that VE; (3) measuring an end tidal CO2 concentration at a steady state; (4) progressively lowering the FGS flow until a time equal to a recirculation time of CO2 in the subject; and (5) deriving VA as the rate of FGS flow at the intersection between an average PETCO2 in a steady state and a line fit to the PETCO2 values after the rise in PETCO2 values begins until the recirculation time.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: November 23, 2021
    Assignee: THORNHILL SCIENTIFIC INC.
    Inventors: Joseph Fisher, David Preiss, Takafumi Azami, Alex Vesely, Eitan Prisman, Ron Somogyi, Steve Iscoe
  • Patent number: 11166636
    Abstract: Embodiments herein include a breath sampling mask, systems, and related methods. In an embodiment, a breath sensing system is included. The breath sensing system can include a breath sampling mask. The breath sampling mask can include a mask housing configured to cover a portion of the face of a patient. The mask housing can define a breath receiving chamber. The breath sampling mask can include a chemical sensor element in fluid communication with the breath sampling mask, where the chemical sensor element can include a plurality of discrete binding detectors. The chemical sensor element can interface with a breath sample collected through the breath sampling mask. Other embodiments are also included herein.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: November 9, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Arthur Guy Erdman, Gregory J. Sherwood, Gregory Kermit Peterson, Justin Theodore Nelson, Michael Mathias Freking
  • Patent number: 11147472
    Abstract: Techniques for determining a volume of exhaled CO2 as a function of time using side-stream capnography, including obtaining flow dynamics measurements of a subject from a flow sensor; obtaining CO2 concentration measurements of the subject from a side-stream CO2 monitor; determining a duration of time (?Tsl) for a sample of gas to flow from a reference point to the side-stream CO2 monitor; synchronizing in time the CO2 concentration measurement with the flow dynamics measurement, based on the determined ?Tsl; and determining a volume of CO2 exhaled as a function of time, based on the flow dynamics measurement and the synchronized CO2 concentration measurement.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: October 19, 2021
    Assignee: COVIDIEN LP
    Inventors: Joshua Lewis Coleman, Michal Ronen
  • Patent number: 11145400
    Abstract: A system and method for generating a pulmonary dysfunction nourishment program, comprises a computing device configured to receive at least a respiratory volume collection relating to a user, generate at least a respiratory parameter of a plurality of respiratory parameter as a function of the respiratory volume collection, determine a pulmonary bundle element as a function of the at least respiratory parameter, identify at least an edible as a function of the pulmonary bundle element, wherein identifying comprises, obtaining a nourishment composition from an edible directory, determining a nourishment deficiency as a function of the pulmonary bundle element, and identifying the at least edible as a function of the nourishment composition, the nourishment deficiency, and an edible machine-learning model, and output a nourishment program as a function of the at least edible.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: October 12, 2021
    Assignee: KPN INNOVATIONS, LLC.
    Inventor: Kenneth Neumann
  • Patent number: 11129545
    Abstract: A breath collection device can detect changes associated with pathogenesis of a disease, such as COVID-19, including biomarkers of immune response for respiratory symptoms, central nervous system injury, and/or peripheral nervous system injury in user breath and/or odor. The breath collection device can detect concentrations of alcohol, acetone, and carbon monoxide in user breath samples. A breath sample can be received in an internal bladder of the device for sensor analysis. Concentrations of alcohol, acetone, and carbon monoxide can be determined by calibrated calculation. A detection method for alcohol, acetone, and carbon monoxide can provide a non-invasive, rapid, and selective detection of gases in a variety of applications in virus detection as well as agricultural and homeland security.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: September 28, 2021
    Assignee: University of South Florida
    Inventors: Tiffany Crystal Miller, Salvatore Domenic Morgera, Stephen Edward Saddow, Arash Takshi
  • Patent number: 11129950
    Abstract: A system and method for monitoring resuscitation and respiratory mechanics of a patient is provided. A pressure sensor detects air pressure within an air-flow path of a resuscitator and generates a first detection signal in response thereto. A flow-rate sensor detects the flow-rate within the air-flow path and generates a second detection signal In response thereto. A processor receives and processes the first and second detection signals using an algorithm to identify a ventilation rate, a lung pressure, and an air volume corresponding to the respiratory air. A report is generated of real-time feedback about respiration of the patient that includes the ventilation rate, lung pressure, and air volume.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: September 28, 2021
    Assignee: The General Hospital Corporation
    Inventors: Craig Mielcarz, Kevin Cedrone, Data Santorino, Kristian Olson
  • Patent number: 11119036
    Abstract: A sensor arrangement (50) encompasses a reaction subassembly (72) having a housing (52) and having a detector subassembly (54), there being provided in the housing (52) a layered component arrangement (60) that encompasses: a luminophore-containing reaction laminate (62) that is excitable, by irradiation with a first electromagnetic radiation of a first wavelength, to emit a second electromagnetic radiation of a second wavelength different from the first wavelength; and a temperature-detection laminate (64) emitting an infrared radiation; the housing (52) comprising an opening (78a, 78b) through which a fluid is introducible; the housing (52) comprising a reaction window (66a) and a temperature-sensing window (66b) arranged physically remotely therefrom; the one reaction window (66a) transmitting the first (E1) and the second electromagnetic radiation (E2); and the temperature-sensing window (66b) being penetrable by infrared radiation (I); the detector subassembly (54) encompassing: a radiation source (
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: September 14, 2021
    Assignee: HAMILTON BONADUZ AG
    Inventors: Marco Giardina, Bernd Offenbeck, Christoph Schranz, Thomas Laubscher, Dominik Novotni, Dirk Schönfuss
  • Patent number: 11103159
    Abstract: A method of detecting hypoxia. Detecting hypoxia includes detecting, in exhaled breath, at least one indicator for hypoxia. The at least one indicator is selected from the group consisting of pentanal, 2-pentanone, 2-hexanone, 2-heptanone, 2-cyclopenten-1-one, and 4-butyrolactone.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: August 31, 2021
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventors: Sean W. Harshman, Brian A. Geier, Claude C. Grigsby, Jeffrey B. Phillips, Darrin K. Ott
  • Patent number: 11077266
    Abstract: An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: —obtaining input of a series of logistically attainable PetX values for a series of respective breaths: —determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths: and—controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: August 3, 2021
    Assignee: THORNHILL SCIENTIFIC INC.
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito, Olivia Sobczyk, Anne Battisti-Charbonney, Daniel Michael Mandell
  • Patent number: 11058324
    Abstract: Apparatuses are described to accurately determine a gas concentration of a sample of a patient's breath. The apparatuses may include a sample compartment, a breath speed analyzer, a gas analyzer, and a processor. The sample compartment includes an inlet that receives the breath. The breath speed analyzer determines the speed of a portion of the breath. The gas analyzer determines a gas concentration. The processor includes an algorithm that determines a degree of non-homogeneity of the sample based on the speed, and a corrected gas concentration based on the degree of non-homogeneity. In some variations, the gas correction is determined independently of patient cooperation. Apparatuses may be tuned based on the intended population's expected breathing pattern ranges such that the sample compartment is filled with a homogenous end-tidal gas sample regardless of an individual's breathing pattern. These apparatuses are useful, for example, for end-tidal CO analysis. Methods are also described.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: July 13, 2021
    Assignee: CAPNIA, INC.
    Inventors: Anthony D. Wondka, Anish Bhatnagar
  • Patent number: 11054360
    Abstract: A device for measuring and tracking over time the quantity or concentration of a component in a fluid comprises: a sensor capable of measuring a quantity or concentration of the component in the fluid and providing a quantitative signal for tracking this quantity or concentration over time; a signal-processing module comprising a low-pass filter of the quantitative tracking signal; and an output interface for providing the filtered quantitative tracking signal. The signal-processing module comprises an estimator of a value of instantaneous trend of variation of the quantitative tracking signal in a predetermined sliding time window. Also provided is means for adjusting over time a high cutoff frequency of the low-pass filter according to the estimated value of instantaneous trend of variation.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: July 6, 2021
    Assignee: eLICHENS
    Inventor: Thanh Trung Le
  • Patent number: 11033202
    Abstract: Methods and systems to determine the lung clearance index (LCI) or other indices of ventilation inhomogeneity of lungs of a paediatric subject are provided. Inert tracer gas is washed-in and the wash-out is conducted by inhaling atmospheric air from the surroundings and exhaling to a confined space until the end-tidal tracer gas concentration has fallen below a predetermined fraction of the starting concentration. The LCI is calculated as the ratio between the cumulative expired volume (VCE) required to clear the inert tracer gas concentration from the lungs below a predetermined fraction of the starting concentration and the functional residual capacity (FRC) determined by dividing the net volume of inert tracer gas exhaled with the difference in end-tidal fractional concentration of the inert tracer gas at the start and end of the wash-out period; where VCE is determined by measuring the total volume in the collection bag after completed wash-out period.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: June 15, 2021
    Assignee: PULMOTRACE APS
    Inventor: Jørgen G. Nielsen
  • Patent number: 11009501
    Abstract: Device for measuring the concentration of gases in exhaled air and measurement procedure used, such device comprising a first air inlet (1), a second air inlet (3) with a nitric oxide filter (4), a pump (5), a nitric oxide sensor (6), a first valve (8) located downstream from the first air inlet (1) and upstream from the sensor (6), a second valve (9) located downstream from the second air inlet (3) and upstream from the sensor (6), a third valve (10) located downstream from the sensor (6) in a first fluid line that conducts air to a first air outlet (12), and a fourth valve (11) located downstream from the sensor (6) in a second fluid line that conducts air to a second air outlet (13), wherein the pump (5) is located in the second fluid line.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: May 18, 2021
    Assignee: EVERSENS, S.L.
    Inventors: Francisco Javier Arregui San Martin, Miguel Angel Arangoa Ortega, Leyre Ruete Ibarrola, Ignacio Raul Matias Maestro, Juan Maria Perez Azpeitia
  • Patent number: 11000623
    Abstract: A personal air treatment device is used to treat air with UV irradiation and with scents. The scents may be used as an attractant or masking for hunting. Multiple devices may be controlled by a smartphone application to strategically alter scent dispersion according to local wind patterns, user location, and relative device location. Similar air treatment devices may be integrated with a particulate mask or used to otherwise treat the air around a user.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: May 11, 2021
    Inventor: Tuan Quoc Dam
  • Patent number: 11004667
    Abstract: A portable ion mobility spectrometry apparatus (1) for detecting an aerosol and a method for using the apparatus. The apparatus comprises an ion mobility spectrometer (3); a portable power source (5) carried by the apparatus for providing power to the apparatus (1); an inlet (7) for collecting a flow of air to be tested by the spectrometer (3); a heater (4) configured to heat the air to be tested to vapourise an aerosol carried by the air and a controller (2) configured to control the spectrometer (3) to obtain samples from the heated air, wherein the controller is configured to increase a heat output from the heater (4) for a selected time period before obtaining samples from the heated air.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: May 11, 2021
    Assignee: SMITHS DETECTION-WATFORD LIMITED
    Inventors: David Sharp, Alastair Clark, William Munro, Paul Arnold, John Fitzgerald, David Cutmore, Rod Wilson
  • Patent number: 11000660
    Abstract: A face mask for delivering oxygen to, and sampling carbon dioxide exhaled from, a subject includes a partition wall that divides the mask into a subject respiratory space that primarily contains carbon dioxide exhaled by the subject, and an oxygen reservoir space that primarily contain oxygen. The partition wall includes one or two holes to which naris conduits are respectively connected. The naris conduit are positioned in proximity to the subject's nares to closely obtain carbon dioxide samples. The naris conduits enable oxygen to flow from the oxygen reservoir space to the subject respiratory space during inhalation, while quickly expelling traces of CO2, and they configured such that exhaled CO2 quickly fills them up, during exhalation, and while expelling oxygen traces back to the oxygen reservoir space. During exhalation.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: May 11, 2021
    Assignee: ORIDION MEDICAL 1987 LTD.
    Inventors: Konstantin Goulitski, Michael Kertser
  • Patent number: 10977793
    Abstract: A dynamic analysis apparatus includes a hardware processor. The hardware processor is configured to perform the following, calculate a prediction rate multiplied by a respiratory function value of the subject in predicting the respiratory function value when an exclusion target portion is excluded; obtain input of the exclusion target portion in an anatomical unit from the input unit, based on the anatomical unit, specify a partial region of the lung field in which a characteristic amount relating to a respiratory function in the plurality of frame images is calculated, calculate the characteristic amount related to the respiratory function in the partial region of the lung field specified from the plurality of frame images and the characteristic amount related to the respiratory function of an entire lung field, and calculate the prediction rate based on a characteristic amount ratio which is a ratio of the two calculated characteristic amounts.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: April 13, 2021
    Assignee: KONICA MINOLTA, INC.
    Inventors: Kenta Shimamura, Noritsugu Matsutani
  • Patent number: 10918329
    Abstract: Methods and apparatus are disclosed for determining the occurrence of a closed or open apnea. Respiratory air flow from a patient is measured to give an air flow signal. The determination of an apnea is performed by applying an oscillatory pressure waveform of known frequency to a patient's airway, calculating a complex quantity representing a patient admittance (12) and comparing its value with ranges (14, 16) indicative of open or closed apneas. The method distinguishes open from closed apneas even when the model used to calculate admittance is not based on details of the respiratory apparatus. In addition the patient admittance may be compared with admittance during normal breathing to avoid having to characterize the airway.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: February 16, 2021
    Inventors: David John Bassin, John David Oates, Ronald James Huby, Benriah Goeldi
  • Patent number: 10914715
    Abstract: The invention relates to an analysis device for determining a measurement variable based on the concentration of one or more contents of a sample, comprising: a digestion reactor with a gas inlet and a gas outlet; a measuring device which is connected to the gas outlet of the digestion reactor; a control and analysis device which is designed to receive and process measurement values that are registered by the measuring device and are based on the measurement variable; an oxygen generating device; and a gas line system which connects the oxygen generating device to the gas inlets of the digestion reactor in order to supply oxygen generated by the oxygen generating device to the digestion reactor, wherein the gas line system comprises a gas storage device which has at least one chamber with a variable volume for receiving an oxygen quantity to be stored.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: February 9, 2021
    Assignee: Analytik Jena AG
    Inventors: Christiane Ehrling, Heiko Henneberg, Robert Knöfel, Kristin Scheide
  • Patent number: 10881821
    Abstract: The present disclosure pertains to a mechanical ventilator system configured to control a pressurized flow of breathable gas for delivery to a subject based on alveolar ventilation of the subject. The mechanical ventilator system comprises a pressure generator configured to generate the pressurized flow of breathable gas for delivery to the subject, the pressure generator configured to control one or more ventilation parameters of the pressurized flow of breathable gas according to a prescribed mechanical ventilation therapy regime; one or more sensors configured to generate output signals conveying information related to the alveolar ventilation of the subject; and one or more hardware processors configured by machine-readable instructions to: determine the alveolar ventilation of the subject based on the output signals; and cause the pressure generator to adjust the one or more ventilation parameters of the pressurized flow of breathable gas based on the determined alveolar ventilation.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: January 5, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: William Anthony Truschel, Joshua Scott Snyder
  • Patent number: 10859473
    Abstract: Described herein are bioaerosol detection systems and methods of use.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: December 8, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Chang-Yu Wu, Xiao Jiang, Maohua Pan, John Lednicky, Alexandros Demetrios Theodore, Zhonghui Hugh Fan, Nima Afshar Mohajer
  • Patent number: 10850052
    Abstract: A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: December 1, 2020
    Assignee: THORNHILL SCIENTIFIC INC.
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito
  • Patent number: 10819837
    Abstract: Systems and methods for user exhalation and environmental air analysis are implemented in an integrated or dockable analysis architecture including an opening adjacent a device microphone to admit an exhalation of a user while the user is speaking. In an embodiment, the opening leads to a passageway having at least one gas sensor therein, located such that a user exhalation entering the opening will impinge on the at least one gas sensor. A processor is linked to the gas sensor, and is configured to receive sensor signals from the gas sensor and generate biological information for the user.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: October 27, 2020
    Assignee: Motorola Mobility LLC
    Inventors: Scott DeBates, Douglas Lautner, Daryl C. Cromer, George Standish, Nigil George Valikodath
  • Patent number: 10752111
    Abstract: Levels of substance use, location, and vital signs are remotely monitored for a subject. In one embodiment, the system includes a testing device and a communication device. The testing device obtains a breathalyzer sample from a test subject and determines a substance level. The communication device reports the substance level to a remote monitoring station. In addition, location and camera functions of the communication device can report additional information for verification and system integrity. In other embodiments, the system can be incorporated into an ankle bracelet for monitoring movement of an individual or into a vehicle system to prevent operation while impaired.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: August 25, 2020
    Assignee: Robert F. Nienhouse 1997 Declaration of Trust
    Inventor: Robert Frank Nienhouse
  • Patent number: 10750738
    Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: August 25, 2020
    Assignee: TRANSMEDICS, INC.
    Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Thomas H. Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
  • Patent number: 10743798
    Abstract: The invention is directed to a method of generating and measuring transiently evoked otoacoustic emissions (TEOAE) acoustic signals generated in the cochlea using a scheme of stimulating both inner ears simultaneously, left ear alone, and right ears alone with at least two different first and second averaging buffers per ear in a switching scheme with automated detection of contralateral suppression of TEOAE via statistical analysis of the differences of suppressed and unsuppressed responses.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: August 18, 2020
    Assignee: PATH medical GmbH
    Inventors: Andre Lodwig, Johann Oswald, Thomas Janssen
  • Patent number: 10732099
    Abstract: A gas analysis device includes a laser light source configured to output a laser beam, an irradiation unit configured to irradiate a measurement region including measurement target gas with the laser beams in plural directions, plural photoreceivers each configured to receive a laser beam having passed through the measurement region and output an electric signal according to intensity of the received laser beam, and an analyzer configured to analyze the physical state of the measurement target gas based on the electric signal output from each photoreceiver. The analyzer sets a function (e.g. two-dimensional polynomial f(X,Y)) representing the physical state (e.g. concentration, temperature) of the target gas at least in the measurement region, and measures the physical state of the target gas by determining a coefficient of each of terms included in the function based on a measured value obtained from the electric signal output from the photoreceiver.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: August 4, 2020
    Assignee: Tokushima University
    Inventor: Yoshihiro Deguchi
  • Patent number: 10702192
    Abstract: A dynamic analysis system includes: an analytic value calculation unit configured to calculate an analytic value in a plurality of time phases on the basis of a dynamic image in the plurality of time phases obtained by performing dynamic photography on the chest of a subject; a ventilation state calculation unit configured to calculate, using a non-linear function, an index value representing a ventilation state of a lung field from the analytic value in the plurality of time phases; a display unit; and a control unit configured to display the index value calculated on the plurality of time phases, on the display unit.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: July 7, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Masayuki Nakazawa, Keiko Itaya
  • Patent number: 10667722
    Abstract: The fat burning analyzer includes a sampling part, an analysis unit and a processing unit. The sampling part collects a breath sample from the user, information on the conditions of the breath sample collection, and provides a sampling signal correlated to the collection condition of the breath sample. The analysis unit provides a detection signal corresponding to an acetone concentration in the collected breath sample and, as such, provides information on the breath acetone of the user (during exercise or resting). The processing unit receives the sampling signal and/or detection signal, and evaluates the sampling signal and/or the detection signal. The evaluation provides information correlated to the fat burning intensity of the user. These information can be provided as an output signal by the processing unit. Accordingly, the processing unit is equipped to provide an output signal correlated to the fat burning intensity of the user.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: June 2, 2020
    Assignee: ETH ZÜRICH
    Inventors: Andreas T. Güntner, Sotiris E. Pratsinis
  • Patent number: 10641783
    Abstract: Methods and devices for sampling, processing and identifying acute use of a substance or substances of abuse are provided. Systems and kits for sampling, processing and identifying acute use of a substance of abuse is also provided.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 5, 2020
    Assignee: Hound Labs, Inc.
    Inventors: Michael Scott Lynn, Seong-Kun Oh
  • Patent number: 10631757
    Abstract: A method of diagnosis. The method can include the steps of sampling the breathing of a patient and from the sampling, obtaining a waveform corresponding to a pattern of the breathing of the patient in which the waveform is a repetitive waveform that is indicative of a carbon dioxide concentration in air expired by the patient. The method can also include the steps of processing the waveform to obtain a set of data that reflects the carbon dioxide concentration in the expired air and based on the processing of the waveform, detecting a potential adverse respiratory event in the patient.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: April 28, 2020
    Assignees: THE QUANTUM GROUP, INC.
    Inventor: Chester Heath
  • Patent number: 10575814
    Abstract: A method for assessment and/or monitoring a person's cardiovascular state comprises: using a sound and vibration transducer to acquire a vascular sound signal in order to detect a vascular sound from a cervical, thoracic, abdominal, pelvic, or lower limb region of the person; filtering the vascular sound signal to isolate the vascular sound, said filtering using a filter which attenuates frequencies below a lower cut-off frequency in a range of 100-300 Hz; and analyzing the filtered sound signal in order to determine whether an indication of a dicrotic notch in the vascular sound exceeds a set threshold.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: March 3, 2020
    Assignee: VIEWCARE TECHNOLOGIES 1 APS
    Inventors: Diana KjÆr Thing Riknagel, Johannes Jan Struijk, Henrik Zimmermann