Qualitative Or Quantitative Analysis Of Breath Component Patents (Class 600/532)
  • Patent number: 10752111
    Abstract: Levels of substance use, location, and vital signs are remotely monitored for a subject. In one embodiment, the system includes a testing device and a communication device. The testing device obtains a breathalyzer sample from a test subject and determines a substance level. The communication device reports the substance level to a remote monitoring station. In addition, location and camera functions of the communication device can report additional information for verification and system integrity. In other embodiments, the system can be incorporated into an ankle bracelet for monitoring movement of an individual or into a vehicle system to prevent operation while impaired.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: August 25, 2020
    Assignee: Robert F. Nienhouse 1997 Declaration of Trust
    Inventor: Robert Frank Nienhouse
  • Patent number: 10750738
    Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: August 25, 2020
    Assignee: TRANSMEDICS, INC.
    Inventors: Robert Fishman, Robert Havener, Ihab Abdel Fattah, Anas Abdelazim, Scott Newell, Thomas H. Bishop, Tamer Khayal, Stanley Kyi, Ron Taylor, Doug Harriott, Matthew De Remer, Paul Murray, John Sullivan, Mark Anderson, Richard Bringham, Michael Van Driel, Waleed Hassanein
  • Patent number: 10743798
    Abstract: The invention is directed to a method of generating and measuring transiently evoked otoacoustic emissions (TEOAE) acoustic signals generated in the cochlea using a scheme of stimulating both inner ears simultaneously, left ear alone, and right ears alone with at least two different first and second averaging buffers per ear in a switching scheme with automated detection of contralateral suppression of TEOAE via statistical analysis of the differences of suppressed and unsuppressed responses.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: August 18, 2020
    Assignee: PATH medical GmbH
    Inventors: Andre Lodwig, Johann Oswald, Thomas Janssen
  • Patent number: 10732099
    Abstract: A gas analysis device includes a laser light source configured to output a laser beam, an irradiation unit configured to irradiate a measurement region including measurement target gas with the laser beams in plural directions, plural photoreceivers each configured to receive a laser beam having passed through the measurement region and output an electric signal according to intensity of the received laser beam, and an analyzer configured to analyze the physical state of the measurement target gas based on the electric signal output from each photoreceiver. The analyzer sets a function (e.g. two-dimensional polynomial f(X,Y)) representing the physical state (e.g. concentration, temperature) of the target gas at least in the measurement region, and measures the physical state of the target gas by determining a coefficient of each of terms included in the function based on a measured value obtained from the electric signal output from the photoreceiver.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: August 4, 2020
    Assignee: Tokushima University
    Inventor: Yoshihiro Deguchi
  • Patent number: 10702192
    Abstract: A dynamic analysis system includes: an analytic value calculation unit configured to calculate an analytic value in a plurality of time phases on the basis of a dynamic image in the plurality of time phases obtained by performing dynamic photography on the chest of a subject; a ventilation state calculation unit configured to calculate, using a non-linear function, an index value representing a ventilation state of a lung field from the analytic value in the plurality of time phases; a display unit; and a control unit configured to display the index value calculated on the plurality of time phases, on the display unit.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: July 7, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Masayuki Nakazawa, Keiko Itaya
  • Patent number: 10667722
    Abstract: The fat burning analyzer includes a sampling part, an analysis unit and a processing unit. The sampling part collects a breath sample from the user, information on the conditions of the breath sample collection, and provides a sampling signal correlated to the collection condition of the breath sample. The analysis unit provides a detection signal corresponding to an acetone concentration in the collected breath sample and, as such, provides information on the breath acetone of the user (during exercise or resting). The processing unit receives the sampling signal and/or detection signal, and evaluates the sampling signal and/or the detection signal. The evaluation provides information correlated to the fat burning intensity of the user. These information can be provided as an output signal by the processing unit. Accordingly, the processing unit is equipped to provide an output signal correlated to the fat burning intensity of the user.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: June 2, 2020
    Assignee: ETH ZÜRICH
    Inventors: Andreas T. Güntner, Sotiris E. Pratsinis
  • Patent number: 10641783
    Abstract: Methods and devices for sampling, processing and identifying acute use of a substance or substances of abuse are provided. Systems and kits for sampling, processing and identifying acute use of a substance of abuse is also provided.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 5, 2020
    Assignee: Hound Labs, Inc.
    Inventors: Michael Scott Lynn, Seong-Kun Oh
  • Patent number: 10631757
    Abstract: A method of diagnosis. The method can include the steps of sampling the breathing of a patient and from the sampling, obtaining a waveform corresponding to a pattern of the breathing of the patient in which the waveform is a repetitive waveform that is indicative of a carbon dioxide concentration in air expired by the patient. The method can also include the steps of processing the waveform to obtain a set of data that reflects the carbon dioxide concentration in the expired air and based on the processing of the waveform, detecting a potential adverse respiratory event in the patient.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: April 28, 2020
    Assignees: THE QUANTUM GROUP, INC.
    Inventor: Chester Heath
  • Patent number: 10575814
    Abstract: A method for assessment and/or monitoring a person's cardiovascular state comprises: using a sound and vibration transducer to acquire a vascular sound signal in order to detect a vascular sound from a cervical, thoracic, abdominal, pelvic, or lower limb region of the person; filtering the vascular sound signal to isolate the vascular sound, said filtering using a filter which attenuates frequencies below a lower cut-off frequency in a range of 100-300 Hz; and analyzing the filtered sound signal in order to determine whether an indication of a dicrotic notch in the vascular sound exceeds a set threshold.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: March 3, 2020
    Inventors: Diana KjÆr Thing Riknagel, Johannes Jan Struijk, Henrik Zimmermann
  • Patent number: 10576329
    Abstract: The present invention provides group performance monitoring systems and methods. In one exemplary embodiment, a group monitoring device includes a display configured to display, during an athletic activity, a plurality of individual performance metrics relating to a plurality of individuals engaged in the athletic activity, each individual performance metric relating to one of the plurality of individuals; and an input to manipulate the display.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: March 3, 2020
    Assignee: adidas AG
    Inventors: Meg Susan Burich, Qaizar Hassonjee, Roger Armitage, Markus Strecker, Hagen Diesterbeck
  • Patent number: 10568541
    Abstract: Methods and systems are disclosed for the detecting of whether a subject has a lung disorder such as asthma, tuberculosis or lung cancer. Monitoring the subject's health and prognosis is also disclosed.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: February 25, 2020
    Assignee: TricornTech Taiwan
    Inventors: Li-Peng Wang, Chi-Lin Young, Chien-Lin Huang, Tsung-Kuan A. Chou
  • Patent number: 10524659
    Abstract: An electronic apparatus is provided. The electronic apparatus includes a communicator configured to receive a plurality of biometric (bio) signals of a user from an external device; and a processor configured to determine a body condition of the user according to whether each of the received plurality of bio signals is in a normal range, wherein the processor, is further configured to control the communicator to transmit information about the determined body condition to an external device corresponding to the determined body condition among a plurality of external devices, and wherein the determination of a body condition varies as a function of the user having either a symptom or a disease.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: January 7, 2020
    Assignee: Samsung Electronics Co., Ltd
    Inventors: Seong-wook Jo, Su-ho Lee, Jin-seob Kim, Jae-hyun Park, Yong-chan Lee
  • Patent number: 10517530
    Abstract: Methods, systems, and devices are described for providing risk evaluation and mitigation strategies for use with modified risk products or other tobacco products, and in particular, associated with nicotine and tobacco products.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: December 31, 2019
    Assignee: Juul Labs, Inc.
    Inventor: Gal A. Cohen
  • Patent number: 10495573
    Abstract: An apparatus for measuring the optical absorption of airborne matter or other light absorbing species in a sample airflow. The apparatus comprises a flow path through a fibrous filter to collect light absorbing species in the sampled air. The filtered airflow may subsequently pass through a second filter, used for reference measurements. At least one light source impinges in the filter generating one or two optical signals to determine the light absorption of particulate matter or other species in the sampled airflow. The apparatus includes at least one auxiliary sensor in the sample flow path to monitor an environmental factor, such as temperature. During a training period, a mathematical model of the apparatus' environmental sensitivity is derived. Using the mathematical model and measurements from the auxiliary sensor, optical signals are compensated in real time to increase the precision and accuracy of light absorption measurements recorded under fluctuating environmental conditions.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: December 3, 2019
    Inventors: Julien J. Caubel, Troy E. Cados, Thomas W. Kirchstetter
  • Patent number: 10478094
    Abstract: A ketone measurement and analysis system provides various features for enabling health program participants to interpret their ketone measurements, such as breath acetone measurements. One such feature breaks down ketone measurements into causal components. For example, the system may generate and display an estimate of how much of a participant's ketone measurement is attributable to stored fat metabolism versus consumption of a “confounding substance” such as dietary fat and/or exogenous ketones. The system may also estimate the contributions of specific confounding substances, and/or the contributions of other factors or events (such as exercise, interrupted sleep, a missed medication, etc.) that affect ketone levels. Another feature involves the generation and display of target ketone levels that are personalized for the participants. The system may generate the measurement breakdowns and target ketone levels by applying data mining algorithms to aggregated data of many program participants.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: November 19, 2019
    Assignee: Invoy Holdings, LLC
    Inventor: Lubna M. Ahmad
  • Patent number: 10478115
    Abstract: Light weight personal handheld home monitoring and managing device, which includes a Sound Sensor network/array of Sound Sensor networks combined with an Artificial Neural Network (ANN) and a build in system and methods, making this device an intelligent and portable apparatus to address specific health issues. The combined apparatus is used for managing and/or guidance and/or diagnosing and/or controlling and managing purposes. This present version of the apparatus will address pulmonary disorders and diseases or similar ailments.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: November 19, 2019
    Assignee: SpiroFriend Technology ApS
    Inventor: Dan Avrahamson
  • Patent number: 10458992
    Abstract: A gas analysis device includes a canister with a cavity that is configured to receive a gas sample. A sensor is in fluid communication with the cavity and analyzes a portion of the gas sample that is received from the canister. The device also includes a blower assembly in fluid communication with the sensor. The blower assembly is configured to selectively draw a portion of the gas sample from the canister past the sensor so that the sensor is exposed to the portion of the gas sample.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: October 29, 2019
    Assignee: GM Nameplate, Inc.
    Inventors: Danius Silkaitis, Steven A. Rodriguez, David A. Herrin, Stephen M. Bailey
  • Patent number: 10390739
    Abstract: A method of analyzing breathing data representing a shape of the trunk of a subject 104 as a function of time to monitor and/or analyze the subject's breathing pattern. The data is measured and processed into a data array relating to a 2-dimensional grid having grid points, a position in space of the shape at each grid point and points of time. The method includes the steps of mapping the data array onto a 2-dimensional array, decomposing the 2-dimensional array and forming a signature of the subject 104 from the decomposed 2-dimensional array representing a motion pattern.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: August 27, 2019
    Inventors: Joan Lasenby, Willem Hessel De Boer
  • Patent number: 10393716
    Abstract: Control logic, device and method including same configured to receive a measured carbon dioxide (CO2) related parameter of a patient, to obtain a patient specific baseline for said CO2 related parameter, the patient specific baseline determined based on a characteristic of the patient; to compute a deviation of the measured CO2 related parameter from the patient specific baseline; and to trigger an alarm when the deviation crosses a predetermined threshold value.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: August 27, 2019
    Assignee: ORIDION MEDICAL 1987 LTD.
    Inventors: Seamus Maguire, Moshe Mandelbaum
  • Patent number: 10342456
    Abstract: An apparatus and method is provided for analyzing a breathing gas flowing along a breathing tubing for subject breathing. The breathing gas comprises breathing cycles having different phases. Liquid particles can be delivered intermittently depending on the phase, or continuously into the breathing gas. The apparatus comprises a gas sample supplier for adjusting gas sample supply from the breathing gas, and a gas analyzer for receiving the gas sample adjusted by the gas sample supplier and for measuring the gas sample property. The apparatus further comprises a processing unit for receiving a signal indicative of one of the phases of the breathing cycle and the delivery timing of the liquid particles. The processing unit is able to control the sample supplier based on the signal to limit access of liquid particles with the gas sample towards the gas analyzer.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: July 9, 2019
    Assignee: General Electric Company
    Inventor: Heikki Antti Mikael Haveri
  • Patent number: 10285642
    Abstract: A wearable breath analysis device is disclosed that may be worn, for example, around the neck or wrist of a user. The wearable device may be a stand-along device (in which case it may include a display that provides a user interface), or may operate in conjunction with a smartphone or other command device. The wearable device may include auditory and/or vibratory notice and communications features or capabilities, for example, such as a reminder or notice to conduct a breath analyte measurement, instructions to the user in the course of conducting the measurement, and notice of the breath analyte measurement results. The auditory or vibratory notice may be provided at the wearable, and/or at the command device where a command device is used. Related methods also are provided.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: May 14, 2019
    Assignee: Invoy Holdings, LLC
    Inventors: Lubna Ahmad, Salman Ahmad, Zachary Smith
  • Patent number: 10258276
    Abstract: Methods of coaching a user of a breathalyzer to make use of correct blowing technique when blowing into the breathalyzer are provided. Methods of setting up a breathalyzer such that it adjusts a breathalyzer's parameters to account for jurisdictional variations in blood and/or breath alcohol limits and other standards are also provided.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: April 16, 2019
    Assignee: Now Group UK Ltd
    Inventor: Hunter David Abbott
  • Patent number: 10251581
    Abstract: Devices and methods for measuring and quantifying airflow through the adult human nose by detecting and measuring the amount of moisture condensate in contact with a pair of flat surfaces or substrates positioned beneath the patient's nose for a predetermined length of time, usually about three (3) seconds. The device comprises a microprocessor, a memory, an output device and a moisture sensing unit. The moisture sensing unit, comprising twin left and right detectors, produces output signals representative of the amounts of moisture condensate in contact with the left and right detectors, respectively. The microprocessor determines the volume density, current density, or relative humidity density from a series of measurements of the condensation as it propagates and decays during exhalation. The microprocessor stores the results in the memory and transmits the data, as well as calculated nasal condition information, to the output device, preferably a digital display.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: April 9, 2019
    Inventor: Randolph B. Capone
  • Patent number: 10244198
    Abstract: A system for testing an individual for illicit or other substances is described. The system operates in tandem with a mobile device (smartphone) application, which employs a camera of the mobile device to capture and record the self-administered specimen collection process for verification and rule compliance. The system guides the user through the process via on-screen prompts on the mobile device, and includes tracking of the collected specimen from the moment of collection until it is sealed in a tamper-proof container to be mailed for external testing at a lab. A breathalyzer may also be used with the system to test for the presence of alcohol in the user's body, the use of which is also monitored and recorded via the on-board camera of the mobile device for verification.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: March 26, 2019
    Inventor: James Kirk Cizerle
  • Patent number: 10188295
    Abstract: Methods and systems for an integrated sensor network are described. In one embodiment, sensor data may be accessed from a plurality of motion sensors and a bed sensor deployed in a living unit for a first time period. An activity pattern for the first time period may be identified based on at least a portion of sensor data associated with the first time period. The activity pattern may represent a physical and cognitive health condition of a person residing in the living unit. Additional sensor data may be accessed from the motion sensors and the bed sensor deployed for a second time period. A determination of whether a deviation of the activity pattern of the first time period has occurred for the second time period may be performed. An alert may be generated based on a determination that the derivation has occurred. In some embodiments, user feedback is captured on the significance of the alerts, and the alert method is customized based on this feedback. Additional methods and systems are disclosed.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: January 29, 2019
    Assignee: The Curators of the University of Missouri
    Inventors: Marjorie Skubic, Marilyn J. Rantz, Mihail Popescu, Shuang Wang, Isaac J. Sledge, Rainer Dane A. Guevara, Elena Florea, James M. Keller
  • Patent number: 10178963
    Abstract: A gas collection apparatus for use by a user includes a housing with an inlet and an outlet to permit a breath sample to flow therethrough. The housing includes a first compartment and a second compartment, a chemo-resistive analysis assembly having a substrate coupled to a sensor array and disposed within the first compartment, the substrate being operably connected to a voltage control unit coupled to the housing to heat the sensor array to a desired temperature, a resistance control unit coupled to the housing to measure resistance in the sensor array, an optical analysis assembly having a light-emitting diode array and a photodiode array coupled to the second compartment, and a processor coupled to the housing and operably connected to the chemo-resistive analysis and optical analysis assemblies.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: January 15, 2019
    Assignee: DYNOSENSE, CORP.
    Inventors: Saeed Azimi, Elaheh Farjami
  • Patent number: 10175247
    Abstract: The invention provides a physical change evaluation device, method, and program capable of easily evaluating physical change from the past to the present, and from the present into the future. A physical change evaluation device 10 acquires a ketone concentration measurement measuring ketone excreted from a user, acquires physical data relating to the body of the user, evaluates physical change in the user based on the acquired ketone concentration measurement and the physical data, and outputs an evaluation result.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: January 8, 2019
    Assignee: Tanita Corporation
    Inventors: Miyuki Kodama, Ayumi Sano, Yasuhiro Kasahara, Naotaka Minagawa, Moe Watabe
  • Patent number: 10168315
    Abstract: A sensor technology comprising a single nano-material (gold nanoparticles and/or carbon nanotube) based sensor or a plurality of sensors in conjunction with a pattern recognition algorithm for non-invasive and accurate diagnosis of tuberculosis caused by M. tuberculosis bacteria in a subject. The sensor technology is suitable for population screening of tuberculosis, particularly in resource-poor and developing countries.
    Type: Grant
    Filed: October 27, 2013
    Date of Patent: January 1, 2019
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Hossam Haick, Morad Nakhleh
  • Patent number: 10159459
    Abstract: A sound localization system includes a multi-mic sound collector and a computing device. The multi-mic sound collector includes a carrier and a plurality of sound receivers removably attached to the sound receivers. The computing device includes a data communicator, a synchronizer, and a processor. The data communicator receives preprocessed audio data from the multi-mic sound collector. The synchronizer synchronizes the preprocessed audio data. The processor analyzes the synchronized audio data to identify and localize a target audio feature. A sound localization method of the sound localization system is also provided. The present invention facilitates monitoring of the functioning or physiological signs of a monitored subject and allows early detection and diagnosis of abnormalities or diseases.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: December 25, 2018
    Assignee: iMEDI PLUS Inc.
    Inventors: Kun-Hsi Tsai, Sheng-Hsiang Kung, Shih-Cheng Lan, Yun-Fan Chang
  • Patent number: 10149953
    Abstract: This invention relates to a breath indicator that is receivable by a part of a breathing assistance apparatus that supplies gas to a patient. The indicator comprises an elongate body having a gas sampling end and an attachment end. The attachment end is adapted to attach to a part of a breathing assistance apparatus and for locating the gas sampling end. The gas sampling end is to be located in a region where gas from the patient is to be exhaled. The gas sampling end being in communication with a sensor comprising a detector material changeable between a first visual indicator state relating to an inhalation phase of the patient, and a second visual indicator state relating to an exhalation phase of the patient. The detector material is capable of changing between the visual indicator states at a sufficient rate to substantially correspond with the inhalation and exhalation phases of the patient.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: December 11, 2018
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Jonathan Mark Church, Simon Boulton, David Robert Kemps
  • Patent number: 10143418
    Abstract: The system of the present invention is intended to provide a simple, out-of-clinic sleep disorders testing tool. It can be used for pretest screening and diagnosis, and post therapy follow-up of patients. The hardware component comprises a disposable sensor pack containing a PVDF airflow sensor and a PVDF pulse wave sensor, each of which is permanently connected to a signal conditioning and communications module configured to communicate with a patient's smartphone via a Bluetooth circuit. An APP stored in the smartphone allows a patient to initiate a diagnostic recording, collect and store digitized data onto the phone and, subsequently, upload data to a secure server for analysis on a host computer following completion of the test.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: December 4, 2018
    Assignee: Dymedix Corporation
    Inventors: James P. Moore, Todd M. Eiken
  • Patent number: 10143425
    Abstract: In one embodiment of the invention, an interactive vital signs scanning method is disclosed including concurrently scanning for a plurality of vital signs with a portable vital signs scanner; detecting movement of the portable vital signs scanner during the scanning for the plurality of vital signs; and determining a measure of quality of the scanning for the plurality of vital signs with the portable vital signs scanner. In another embodiment, a method of improving the quality of vital signs data is disclosed including concurrently sensing data from a plurality of vital signs sensors over a period of time with a portable vital signs scanner; determining a plurality of vital sign values for a respective plurality of vital signs in response to the sensed data from the plurality of vital signs sensors over the period of time; and fusing at least two vital sign values of the plurality of vital sign values for the respective plurality of vital signs.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: December 4, 2018
    Assignee: Scanadu Incorporated
    Inventors: Wenyi Zhao, Brandon Dennis Woolsey, Walter De Brouwer, Eron Anthony Villarreal, Whitney Morgan McGowan, Martin Zizi
  • Patent number: 10139392
    Abstract: A method and an apparatus for breath analysis, the method comprising determining an isotopic composition profile, or a concentration profile of a species, of a first breath cycle; determining a threshold; determining a sampling time; and measuring the isotopic composition, or concentration of the species, during a second breath cycle at the sampling time triggered by reaching the threshold.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: November 27, 2018
    Inventors: Teemu Kääriäinen, Albert Manninen
  • Patent number: 10136839
    Abstract: An airway adaptor includes: an airway case; and an expired gas guiding portion which is connected to the airway case to introduce a respiratory gas to the airway case. The airway case includes: a first respiratory gas flow path in which the respiratory gas flows in a first direction; and a second respiratory gas flow path in which the respiratory gas flows in a second direction opposite to the first direction.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: November 27, 2018
    Inventor: Shinji Yamamori
  • Patent number: 10111606
    Abstract: An integrated condenser is described. This integrated condenser includes an outer surface region on a sampler surface that facilitates condensing at least a component in a received gas-phase sample into liquid-phase droplets on the sampler surface, and aggregating and moving the condensed droplets radially toward an inner surface region on the sampler surface that receives the condensed droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: October 30, 2018
    Assignee: The Regents of the University of California
    Inventors: Cristina Davis, Hamzeh Bardaweel, Konstantin Zamuruyev, Jean-Pierre Delplanque, Nicholas J. Kenyon
  • Patent number: 10111588
    Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: October 30, 2018
    Assignee: Senseonics, Incorporated
    Inventors: Szymon Tankiewicz, Jeremy Emken, Andrew DeHennis, Todd Whitehurst
  • Patent number: 10092221
    Abstract: A method of analyzing breathing data representing a shape of the trunk of a subject 104 as a function of time to monitor and/or analyze the subject's breathing pattern. The data is measured and processed into a data array relating to a 2-dimensional grid having grid points, a position in space of the shape at each grid point and points of time. The method includes the steps of mapping the data array onto a 2-dimensional array, decomposing the 2-dimensional array and forming a signature of the subject 104 from the decomposed 2-dimensional array representing a motion pattern.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: October 9, 2018
    Inventors: Joan Lasenby, Willem Hessel De Boer
  • Patent number: 10034621
    Abstract: Apparatuses are described to accurately determine a gas concentration of a sample of a patient's breath. The apparatuses may include a sample compartment, a breath speed analyzer, a gas analyzer, and a processor. The sample compartment includes an inlet that receives the breath. The breath speed analyzer determines the speed of a portion of the breath. The gas analyzer determines a gas concentration. The processor includes an algorithm that determines a degree of non-homogeneity of the sample based on the speed, and a corrected gas concentration based on the degree of non-homogeneity. In some variations, the gas correction is determined independently of patient cooperation. Apparatuses may be tuned based on the intended population's expected breathing pattern ranges such that the sample compartment is filled with a homogenous end-tidal gas sample regardless of an individual's breathing pattern. These apparatuses are useful, for example, for end-tidal CO analysis. Methods are also described.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: July 31, 2018
    Assignee: Capnia, Inc.
    Inventors: Anthony D. Wondka, Anish Bhatnagar
  • Patent number: 10031126
    Abstract: A system for monitoring an exhaled breath of a subject is described. A breath collector can be configured to receive exhaled breath from a subject. One or more sensors can be configured to output a concentration of a first gas compound in the received exhaled breath, and to output a concentration of a second gas compound in the received exhaled breath. The second gas compound is used to normalize the concentration of the first gas based on different physiological states of the subject. A processor operably coupled to the one or more sensors is configured to calculate a ratio of the first gas compound to the second gas compound based on the determined concentrations, and to determine a normalized concentration of the first gas compound. This ratio may be monitored to evaluate an inflammatory state of the subject.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: July 24, 2018
    Inventors: Donald R. Blake, Alan G. Barbour
  • Patent number: 9986935
    Abstract: A compact, on-airway, respiratory gas analyzer for performing pulmonary function tests incorporates an IR spectroscopy light guide having a curved, rather than linear, sample chamber that lies transverse to a direction of respiratory gas flow. Cooperating with the sample chamber is an impact plate that functions to steer respiratory and test gases impinging on the impact plate into the curved sample chamber. A source of IR energy is at one end of the sample chamber and an electro-optical sensor responsive to IR energy is disposed at an opposite end of the chamber. The respiratory gas analyzer also includes gas flow paths and valving for carrying out lung capacity and lung diffusion tests.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: June 5, 2018
    Assignee: MGC Diagnostics Corporation
    Inventors: David A. Blanton, Charles P. Howard, Joshua L. Stevenson
  • Patent number: 9943248
    Abstract: According to one of aspects, an electronic device used for a phone call includes: a sound input unit to which a sound is input during a phone call; and a sensor that is provided near the sound input unit and detects a substance contained in a gas.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: April 17, 2018
    Inventor: Hideki Hidaka
  • Patent number: 9936897
    Abstract: An improved apparatus and method for capturing and analyzing the end-tidal portion of an exhalation. The CO2 level of air drawn into the system (10) is monitored to distinguish inhalation and exhalation of breath. Upon detection of a decrease in the CO2 level in the air drawn into the system (10), indicating a transition between exhalation and inhalation a pair of flow selector valves (26, 28) are operated to capture the end-tidal volume of air drawn into the system (10) immediately prior to the detection of the decrease in the CO2 level. Incoming air is diverted around the captured volume of air, and the CO2 levels are continually monitored to ensure that the captured volume of air corresponds to the end-tidal portion of an exhalation. Once the captured volume of air is positively identified as the end-tidal portion of an exhalation, the captured volume is routed through a gas analyzer (44) for analysis of one or more predetermined gas levels.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: April 10, 2018
    Assignee: Capnia, Inc.
    Inventors: Lee R. Carlson, Edward A. McClatchie, Joe Martinosky, Ralph Walden, Elvir Causevic
  • Patent number: 9919123
    Abstract: The flow rate of a gaseous sample of exhaled breath through an analytical device is controlled by a pump, and in certain embodiments two pumps. Placement of the analyte sensor in a secondary stream branching off of the primary stream through the device offers further control over the manner, duration, and quantity of the breath that is placed in contact with the sensor.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: March 20, 2018
    Assignee: Circassia AB
    Inventors: Kevin Nason, Jonathan Fay, Bryan P. Flaherty, Bhairavi R. Parikh
  • Patent number: 9901482
    Abstract: A method for manufacturing a protrusion splint comprising an upper support area configured to provide a defined abutment of a maxilla area, and a lower support area configured to provide a defined abutment of a mandible area. The method includes fixing the maxilla area and the mandible area in a first position so that the mandible area is shifted forward relative to the mandible area. A three-dimensional image data set of an air passage in a region of a trachea is created in the first position. The air passage is checked whether an opening value of the air passage corresponds to a target value. A second position of the maxilla area and of the mandible area to each other is defined depending on the checking. The protrusion splint is manufactured so that the mandible area is held relative to the maxilla area in the second position.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: February 27, 2018
    Assignee: HICAT GMBH
    Inventor: Daniel Gruenberg
  • Patent number: 9901384
    Abstract: A medical device may include a stimulation member configured to apply a stimulus to a nerve that is configured to control a contraction of an airway distal to the nerve, and a measurement member configured to measure an effect of the stimulus on the airway. The medical device also may include an energy delivery element configured to deliver energy to tissue defining the airway to reduce an effect of the stimulus on the airway. The energy delivery element may be disposed at or distally of the stimulation member.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: February 27, 2018
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Bryan Allen Clark, Aiden Flanagan, Michael Eppihimer, William Conrad Stoffregen, Juan Gabriel Hincapie Ordonez
  • Patent number: 9888870
    Abstract: The disclosure is directed to intrapleural air leak detection and monitoring. According to various embodiments of the disclosure, an air leak may be detected utilizing at least one sensor to determine whether fluid extracted from a pleural cavity of a patient includes carbon dioxide and/or a second substance. The second substance may be a foreign substance inhaled by the patient to confirm presence of the air leak. The air leak may be further monitored over a period of time by collecting temporally successive measurements associated with detected concentrations of carbon dioxide. Therefore, tissue damage and recovery may be assessed according to objectively collected criteria.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: February 13, 2018
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Dimitrios Miserlis, Kim Cluff, Abby M. Kelly, Suzanne J. Higgins, Max H. Twedt
  • Patent number: 9885693
    Abstract: A measuring system and device (12), a reaction carrier (14) and a measuring method for measuring a concentration of gaseous and/or aerosol components of a gas mixture are provided. The reaction carrier includes flow channels (42) and a coding that is detectable by a position sensor (36) to position the reaction carrier flow channels. At least one flow channel defines a reaction chamber (46) in which optically detectable reaction material (48) is provided. A position sensor detects a relative position of the reaction carrier. A conveying device (28) moves the reaction carrier relative to gas connections (22, 24) of a gas-inlet channel (16) and a gas-outlet channel (16, 18) between a measuring position with gas connections via a first flow channel for flushing the gas inlet channel and gas connections via a second flow channel defining a reaction chamber, for measuring the component of the gas mixture.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: February 6, 2018
    Assignee: Dräger Safety AG & Co. KGaA
    Inventors: Hans-Ullrich Hansmann, Philipp Rostalski
  • Patent number: 9861298
    Abstract: A gas sampling line having a channel for conducting respiratory gases from a patient respiratory interface to a gas monitor, the gas sampling line comprising, i.a., a gas sampling tube comprised of a polyether block amide material, the polyether segments of which comprise polyethyleneoxide. Use of a tube comprised of a polyether block amide material, the polyether segments of which comprise polyethyleneoxide, for sampling of respiratory gases; and a method for sampling of respiratory gases, the method comprising conducting respiratory gases through such a tube. A gas analysis system for analyzing respiratory gases, comprising a gas sampling line as defined above and a gas monitor connectable to the gas sampling line.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: January 9, 2018
    Assignee: Masimo Corporation
    Inventors: Anders Eckerbom, Robert Zyzanski
  • Patent number: 9795324
    Abstract: A computer-implemented method, and related system, for monitoring the wellbeing of an individual by providing eyewear that includes at least one sensor for monitoring the motion of the user. In various embodiments, the system receives data generated by the at least one sensor, uses the data to determine the user's movements using the received data, and compares the user's movements to previously established movement patterns of the user. If the system detects one or more inconsistencies between the user's current movements as compared to the previously established movement patterns of the user, the system may notify the user or a third party of the detected one or more inconsistencies. The system may similarly monitor a user's compliance with a medical regime and notify the user or a third party of the user's compliance with the regime.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: October 24, 2017
    Assignee: Vision Service Plan
    Inventors: Jay William Sales, Richard Chester Klosinski, Jr., Matthew Allen Workman, Meghan Kathleen Murphy, Matthew David Steen
  • Patent number: 9791366
    Abstract: A gas detector (10) includes a cell internal space (130) into which a target gas is supplied, the target gas exhibiting an absorption peak in an absorption spectrum; a light source (410) configured to generate light having at least a wavelength belonging to the absorption peak; and a photodetector (420) configured to detect the light that has emitted from the light source (410) and has propagated through the cell internal space (130). The gas detector (10) further includes a conductive thin film (220) in which a plurality of optical apertures (222) are regularly arranged such that a transmission peak in a transmission spectrum is superimposed over the absorption peak in the absorption spectrum along a wavelength axis. The conductive thin film (220) is provided on an optical path extending from the light source (410) to the photodetector (420), and is provided so as to be contactable with the target gas within the cell internal space (130).
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: October 17, 2017
    Inventors: Yoshiaki Nishijima, Yuta Adachi