Respiratory Patents (Class 600/529)
  • Patent number: 10674960
    Abstract: An intraoral multisensor device includes a mouthpiece, a plurality of sensors at least one of attached to or integrated with the mouthpiece, and a data communications unit configured to receive signals from the plurality of sensors. The mouthpiece has a form to permit stable arrangement at least partially within a person's mouth such that it can remain for hands-free sensing of a plurality of biological parameters. Also, an intraoral multisensor system includes an intraoral multisensor device and a data processing device adapted to communicate with the intraoral multisensor device.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: June 9, 2020
    Assignee: Aidar Health
    Inventor: Gene Yevgeny Fridman
  • Patent number: 10661038
    Abstract: Automated methods provide hypopnea detection for determining a hypopnea event and/or a severity of a hypopnea event. In some embodiments, a calculated short-term variance of a measured respiratory flow signal are compared to first and second proportions of a calculated long-term variance of the measured flow signal. A detection of the hypopnea may be indicated if the first measure falls below and does not exceed a range of the first and second proportions during a first time period. In some embodiments, a hypopnea severity measure is determined by automated measuring of an area bounded by first and second crossings of a short-term measure of ventilation and a proportion of a long-term measure. The detection methodologies may be implemented for data analysis by a specific purpose computer, a detection device that measures a respiratory airflow or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected hypopneas.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: May 26, 2020
    Assignee: RedMed Pty Ltd
    Inventor: Jeffrey Peter Armitstead
  • Patent number: 10660563
    Abstract: Methods and apparatus monitor health by detection of sleep stage. For example, a sleep stage monitor (100) may access sensor data signals related to bodily movement and/or respiration movements. At least a portion of the detected signals may be analyzed to calculate respiration variability. The respiration variability may include one or more of variability of respiration rate and variability of respiration amplitude. A processor may then determine a sleep stage based on one or more of respiration variability and bodily movement, such as with a combination of both. The determination of sleep stages may distinguish between deep sleep and other stages of sleep, or may differentiate between deep sleep, light sleep and REM sleep. The bodily movement and respiration movement signals may be derived from one or more sensors, such as non-invasive sensor (e.g., a non-contact radio-frequency motion sensor or a pressure sensitive mattress).
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: May 26, 2020
    Assignee: ResMed Sensor Technologies Limited
    Inventors: Gareth McDarby, Emer O'Hare, Paul Phillips, Conor Heneghan, Trevor Murray
  • Patent number: 10639477
    Abstract: An example of a system may include an electrode and a pulse generation system. The electrode may be configured to be implanted near a neural target that innervates airways. The pulse generation system may be configured to be operably connected to the electrode to deliver depletion block stimulation through the electrode to alleviate symptoms of pulmonary disease. The pulse generation system and the electrode may be configured to cooperate to capture axons in the neural target. The depletion block stimulation may include a series of pulses at a depletion pulse frequency.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: May 5, 2020
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Manfred Franke, Bryan Allen Clark, Aiden Flanagan, Juan Gabriel Hincapie Ordonez, David J. Ternes
  • Patent number: 10631738
    Abstract: A method and system for the analysis of a patient's oximetry data to detect sleep-disordered breathing is provided. The system employs an algorithm to reliably detect patient arousals and correlate those with accelerated heart rate and oxygen saturation levels in a manner that detects sleep-disordered breathing via the respiratory mask. Initially a timing channel is formed based on a plethsmography signal using an optical finger sensor. Based on the pleth waveform, a respiratory wave form is prepared that represents respiration rate. An arousal mask is applied to the signal based on attenuations in the pleth signal. Once arousals are identified the time required for changes to propagate from the lungs to the blood gas is subtracted from the onset time of the arousal. As a result if the timing agrees with dropping oxygen saturation or falling arterial pH then the arousal is indicated as a chemoreflex related arousal.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: April 28, 2020
    Assignee: The Periodic Breathing Foundation, LLC
    Inventor: Robert W. Daly
  • Patent number: 10631758
    Abstract: A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: April 28, 2020
    Assignee: Pulmonx Corporation
    Inventors: Srikanth Radhakrishnan, Surag Mantri, Ryan Olivera
  • Patent number: 10603540
    Abstract: A device includes: a controller that converts a pressure value detected by a pressure detector into visual or aural lingual pressure information changed depending on a magnitude of the pressure value; and an information output unit, such as a buzzer and a color display LED, that outputs the lingual pressure information in response to a signal from the controller. The information output unit outputs lingual pressure information different depending on a pressing force applied on an elastic balloon by a tongue, allowing users such as patients and elderly people to continue a training without being bored.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: March 31, 2020
    Assignees: JMS Co., Ltd., HIROSHIMA UNIVERSITY
    Inventors: Noboru Ikeda, Yoshihiro Yoshiike, Daiki Aruga, Koichiro Toyota, Kazuhiro Tsuga
  • Patent number: 10575758
    Abstract: A method of a device detects a respiratory effort-related arousal in a respiratory airflow signal of a patient. The method may include computing a measure of consistency of inspiratory flow limitation over a plurality of recent breaths from the signal. The method may further include computing a measure of step change in ventilation indicating a sudden big breath. The method may further include computing a measure indicating a degree of confidence of occurrence of a respiratory effort-related arousal from the measure of consistency of inspiratory flow limitation and the measure of the step change in ventilation.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: March 3, 2020
    Assignee: ResMed Pty Ltd
    Inventor: Dinesh Ramanan
  • Patent number: 10573415
    Abstract: A system and associated method receives, by a database coupled to a communication network, patient medical data from multiple data sources including data retrieved from implantable medical devices implanted in patients. A processor accesses the database to generate a dataset from the medical data having at least one data characteristic matching a corresponding data characteristic of a patient group of at least one patient. At least one subset of the dataset is identified that had a therapy intervention subsequent to a time point that the subset had the matching data characteristic(s). An outcome of the subset is determined and a predictive outcome for the patient group is produced based on the outcome of at least one subset.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: February 25, 2020
    Assignee: Medtronic, Inc.
    Inventors: Amisha S. Patel, Kenneth M. Riff, Luc R. Mongeon
  • Patent number: 10568583
    Abstract: A method for identifying cardiac bradiacardia behavior may include acquiring pulse volume wave data from a sensor associated with a patient, and calculating metrics associated with peaks detected therein. The metrics may include changes in peak amplitudes of pulse volume peaks and in the times of occurrence of pulse volume peaks. Alternative metrics may include changes in frequency domain parameters derived from the time domain pulse volume wave data. Peak amplitude values may be compared to an amplitude baseline, and differences in successive peak occurrence times may be compared to a time baseline. Cardiac bradycardia behavior may be identified by a combination of a decrease in the pulse volume peak amplitude and an increase in successive peak occurrence times. A system to implement the method may include a computing device in data communication with a photo-plethysmograph. Alternative sensors may include a blood pressure cuff and an ECG device.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: February 25, 2020
    Assignee: Intelomed, Inc.
    Inventors: Anne M. Brumfield, Jan K. Berkow
  • Patent number: 10543044
    Abstract: Provided are systems, devices, and methods for planning a medical procedure. An exemplary method includes receiving image data of a patient's chest, identifying the patient's lungs in the image data, determining locations of pleural surfaces of the patient's lungs in the image data, identifying a treatment target in the patient's lungs, generating a three-dimensional (3D) model of the patient's lungs based on the image data, the 3D model showing the pleural surfaces of the patient's lungs and the treatment target, determining whether the treatment target invades the pleural surfaces, displaying a view of the 3D model for viewing by a clinician, receiving input from the clinician regarding a plan for the medical procedure, and displaying the plan for the medical procedure.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: January 28, 2020
    Assignee: COVIDIEN LP
    Inventor: William S. Krimsky
  • Patent number: 10537557
    Abstract: A method of treating a hyperoxia induced disease or disorder associated with GSNO deficiency in a subject in need thereof includes administering to the subject a therapeutically effective amount of GSNO or a GSNO promoting agent.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: January 21, 2020
    Inventors: Thomas M. Raffay, Benjamin M. Gaston
  • Patent number: 10537289
    Abstract: Systems and methods are provided for determining respiration information from physiological signals such as PPG signals. A physiological signal is processed to generate at least one respiration information signal and an autocorrelation sequence is generated based on the at least one respiration information signal. In some embodiments, a respiration peak is identified based on the autocorrelation sequence and a composite peak is generated based on the identified peak and at least one previous respiration peak. Respiration information is calculated based on the composite peak. In some embodiments, a determination is made whether the autocorrelation sequence includes an undesired harmonic. When the autocorrelation sequence includes an undesired harmonic, the autocorrelation sequence may not be used in the calculation of respiration information.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: January 21, 2020
    Assignee: COVIDIEN LP
    Inventors: James Ochs, Scott McGonigle, Paul Addison
  • Patent number: 10531842
    Abstract: There is provided a method and apparatus for adjusting a monitoring system which is arranged to receive measured values of a physiological characteristic of a subject and to generate an alarm when the received measured values meet at least one predefined alarm generation criterion.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: January 14, 2020
    Inventors: Jarno Mikael Riistama, Gerhard Spekowius, Joseph Ernest Rock, Emile Josephus Carlos Kelkboom, Silviu Dovancescu
  • Patent number: 10524725
    Abstract: A device, system and method unobtrusively and reliably detect apnoea of a subject (2). An input unit (11) receives image data of subject. The image data includes a sequence of images over time. A cardiac activity extraction unit (12) extracts from the image data a cardiac activity signal representing the subject's cardiac activity from a skin area of the subject using remote photoplethysmography. A motion signal extraction unit (14) extracts from said image data a motion signal representing motion of a subject's body part caused by breathing of the subject. An analysis unit (16) determines a similarity between said cardiac activity signal and said motion signal. A decision unit (18) detects apnoea of the subject based on the determined similarity.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: January 7, 2020
    Inventor: Vincent Jeanne
  • Patent number: 10518090
    Abstract: An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic never through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: December 31, 2019
    Assignee: RESPICARDIA, INC.
    Inventors: Mark Gelfand, Howard R. Levin, Andrew Halpert
  • Patent number: 10512249
    Abstract: Method and system for generating at least one attention signal indicating a problem for an animal. The method includes attaching at least one sensor to the animal. The sensor generates information about the movement and/or direction of the sensor. The method analyzes the information to generate one attention signal if there is a problem with the animal. The analysis includes a step of calculating an actual inactive value and generating the signal if a condition is fulfilled. The actual inactive value indicates a length of time the animal was inactive over a recent first time period. When the actual inactive value is greater than a boundary value, attention signal is generated. The system is provided with at least one sensor and a computer for carrying out the analysis on the basis of information received form the at least one sensor.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: December 24, 2019
    Inventors: Rudie Jan Hendrik Lammers, Arnoldus Gerardus Franciscus Harbers
  • Patent number: 10512419
    Abstract: A medical system (100) is disclosed that provides a respiratory-based control of at least one medical procedure. In this regard, the medical system (100) includes one or more appropriate sensors (108) for providing respiratory data on a patient (104). This respiratory data is utilized by respiration assessment logic (116) to determine if the respiratory data has exceeded one or more respiration thresholds and which may be equated with a “sudden” respiratory event. Identification of such a sudden respiratory event by the logic (116) results in the suspension of the noted medical procedure. Patient respiration data may also be displayed, for instance in a color that depends upon its magnitude or level.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: December 24, 2019
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Michael W. Craven, Timothy R. Jarvis
  • Patent number: 10485455
    Abstract: An estimation device includes a first converting unit configured to convert a beat signal to a one-dimensional first candidate signal on the basis of a two-dimensional distribution of the beat signal, a second converting unit configured to convert the beat signal to a one-dimensional second candidate signal on the basis of a two-dimensional position change of the beat signal, and a signal deciding unit configured to decide a one-dimensional signal on the basis of the first candidate signal and the second candidate signal.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: November 26, 2019
    Assignee: Oki Electric Industry Co., Ltd.
    Inventors: Kurato Maeno, Kohei Yamamoto
  • Patent number: 10471226
    Abstract: The present invention relates to a patient interface (10) for delivering a flow of breathable gas to a patient (12), comprising: a sealing portion (22) for sealing an interface between the patient interface (10) and a patient's face when the patient (10) interface is worn by the patient (12); a detection unit (30) including a displacement sensor (32, 32?) for generating a displacement signal including information on a displacement of the sealing portion (22) with respect to the patient's face relative to an identified reference position of the sealing portion (22) with respect to the patient's face; one or more actuators (36, 36?, 36?) for positioning at least parts of the sealing portion (22) relative to the patient's face; and a control unit (34) that is configured to actuate the one or more actuators (36, 36?, 36?) based on the displacement signal in order to adjust a position of at least parts of the sealing portion (22) with respect to the patient's face during use.
    Type: Grant
    Filed: February 9, 2015
    Date of Patent: November 12, 2019
    Assignee: Koninklijke Philips N.V.
    Inventor: Matthew John Lawrenson
  • Patent number: 10456063
    Abstract: The disclosure is directed to intrapleural air leak detection and monitoring. According to various embodiments of the disclosure, an air leak may be detected utilizing at least one sensor to determine whether fluid extracted from a pleural cavity of a patient includes carbon dioxide and/or a second substance. The second substance may be a foreign substance inhaled by the patient to confirm presence of the air leak. The air leak may be further monitored over a period of time by collecting temporally successive measurements associated with detected concentrations of carbon dioxide. Therefore, tissue damage and recovery may be assessed according to objectively collected criteria.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: October 29, 2019
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Dimitrios Miserlis, Kim Cluff, Abby M. Kelly, Suzanne J. Higgins, Max H. Twedt
  • Patent number: 10441243
    Abstract: A body sound analysis device includes: acquisition means (210, 220) that acquires information relating to a frequency corresponding to a prescribed feature of a spectrum of a body sound; shifting means (230) that shifts, according to the information relating to the frequency, a plurality of reference spectrums that are references for classifying body sounds, and acquires a frequency shift reference spectrum; and output means (240, 250) that outputs a ratio of a plurality of reference spectrums included in the body sounds on the basis of the body sounds and the frequency shift reference spectrum. According to this body sound analysis device, a plurality of types of sounds included in the body sounds can be favorably analyzed.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: October 15, 2019
    Inventors: Ryushin Kametani, Koichi Ishitoya, Tomohiro Miura, Hideyuki Ohkubo, Tsuyoshi Hasebe
  • Patent number: 10426421
    Abstract: Methods and systems are provided for analyzing a respiratory motion waveform acquired during acquiring imaging data with a molecular imaging device. In one embodiment, a method comprises acquiring imaging data with a molecular imaging apparatus, analyzing a respiratory motion waveform acquired during the acquiring imaging data, and applying gating to the acquired imaging data based on the analyzed respiratory motion waveform. In this way, gating may be applied to the acquired imaging data in order to generate an image for medical diagnosis with increased image quality and accuracy.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: October 1, 2019
    Assignee: General Electric Company
    Inventors: Scott David Wollenweber, Nathan Tibbitts Roberts
  • Patent number: 10420501
    Abstract: A sleep monitoring system (10) for monitoring the sleep of a subject is disclosed. The system comprises a CO2 sensor (21) and a processor (31) communicatively coupled to the CO2 sensor, wherein the processor is adapted to monitor a CO2 concentration from sensor data produced by the CO2 sensor; and derive sleep pattern information from the monitored CO2 concentration, wherein the sleep pattern information comprises at least an indication that the subject is awake and an indication that the subject is asleep. A sleep monitoring method and computer program product are also disclosed.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: September 24, 2019
    Inventors: Jing Su, Rainer Hilbig, Jun Shi, Huibin Wei
  • Patent number: 10410369
    Abstract: A method for electrode placement includes acquiring an image of a body of a patient, such that the image captures a patch that has been placed on the body. Based on the acquired image and the patch appearing therein, one or more preferred locations are calculated on the body for placing one or more respective electrodes to be used in carrying out a procedure in an internal organ of the patient. The preferred locations are displayed to an operator.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: September 10, 2019
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Roy Urman, Ronen Krupnik, Liron Shmuel Mizrahi
  • Patent number: 10368807
    Abstract: Provided herein are methods and systems for validating and interpreting respiratory signals in order to provide comprehensive non-invasive methods to monitor patients at risk for respiratory depression and apnea. In the present invention, data from multiple respiratory monitoring technologies (or from multiple channels of one monitoring technology) is fused so that the patient's true respiratory state may be elucidated.
    Type: Grant
    Filed: October 11, 2014
    Date of Patent: August 6, 2019
    Inventors: Richard J. Melker, Sean Cohen, Huwei Tan
  • Patent number: 10368849
    Abstract: A biopsy device includes a biopsy sample extraction needle having a sample extraction end, a recovery end, and a transport channel linking the extraction and recovery ends. In a first configuration, a valve has a first position wherein the valve directly connects a pump to an ambient vent and the pump can reduce the pressure in at least the sample extraction end. In a second configuration, the valve has a second position wherein the valve directly connects the pump to a fluid reservoir and the pump can draw fluid from the fluid reservoir. In a third configuration, the valve has a third position wherein the valve directly connects the pump to the extraction end and the pump can supply fluid to the extraction end to flush fluid along the transport channel from the extraction end to the recovery end to transport a sample along the transport channel.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: August 6, 2019
    Assignee: C. R. Bard, Inc.
    Inventors: Timothy J. Coonahan, Stanley O. Thompson, Jon Taylor
  • Patent number: 10349883
    Abstract: Airway impedance of a subject using a respiratory treatment device can be measured, in accordance with one or more embodiments. A conduit is configured to communicate a flow of inhaled gas and a flow of exhaled gas to and from an airway of the subject using the respiratory treatment device. A first valve is disposed within the conduit and configured to affect the flow of exhaled gas. One or more sensors are disposed within the conduit and are configured to provide a signal conveying information associated with one or more characteristics of gas exhaled by the subject while the flow of exhaled gas is affected or unaffected by the first valve. An airway impedance monitoring module can be executed by a processor to determine an impedance metric of the airway of the subject based on the information conveyed by the signal provided by the one or more sensors.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: July 16, 2019
    Inventors: Alberto Fazzi, Teunis Johannes Vink, Dirk Erneset Von Hollen
  • Patent number: 10332379
    Abstract: A data collection system collects and stores physiological data from an ambulatory patient at a high resolution and/or a high data rate (“more detailed data”) and sends a low-resolution and/or downsampled version of the data (“less detailed data”) to a remote server via a wireless network. The server automatically analyzes the less detailed data to detect an anomaly, such as an arrhythmia. A two-tiered analysis scheme is used, where the first tier is more sensitive and less specific than the second tier. If the more sensitive analysis detects or suspects the anomaly, the server signals the data collector to send more detailed data that corresponds to a time period associated with the anomaly. The more specific second tier analyzes the more detailed data to verify the anomaly. The server may also store the received data and make it available to a user, such as via a graphical or tabular display.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: June 25, 2019
    Assignee: INFOBIONIC, INC.
    Inventor: Michael Fahey
  • Patent number: 10314515
    Abstract: There is provided a method for dynamically determining a breath related parameter, which includes averaging a breath related parameter over a first period of time, calculating a breath related value over a second period of time and adapting the duration of the first period of time according to the calculated breath related value.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: June 11, 2019
    Assignee: Oridion Medical (1987) Ltd.
    Inventors: Joshua Lewis Colman, David Lain, Boaz Giron
  • Patent number: 10307110
    Abstract: Systems, devices, and methods for determining a user's lung capacity may employ a sound-producing breathing device and a recording device such as a microphone included in a user electronic device (e.g., smart phone or tablet computer). A user may inhale or exhale through the sound-producing breathing device, thereby producing a sound that is received by the microphone and communicated to a processor. The processor may analyze the received sound recording to determine one or more sound intensity values over, for example, the duration of the received sound and/or points in time within the sound recording. The sound intensity values may then be used to determine the user's lung capacity.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: June 4, 2019
    Assignee: Human Resolution Technologies, LLC
    Inventors: Gregory O'Keeffe, Brian Dutton, Mark Seelig, Debra Sarvis, Raymond Cha
  • Patent number: 10282521
    Abstract: Medication management and reporting technology, in which output from at least one sensor configured to sense physical activity in a building in which medication of a patient is located is monitored and a determination is made to capture one or more images of the medication based on the monitoring. A camera is used to capture an image of the medication and the captured image is analyzed to detect a state of the medication. Information regarding a schedule by which the medication should be taken by the patient is accessed and an expected state of the medication is determined. The detected state is compared with the expected state and a determination is made that the patient has departed from the schedule based on the comparison revealing that the detected state does not match the expected state. A message indicating the departure from the schedule is sent based on the determination.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: May 7, 2019
    Assignee: Incorporated
    Inventors: Mark Andrew Hanson, Elizabeth Leslie Manson
  • Patent number: 10278639
    Abstract: Described herein are various embodiments of a method and system for sleep detection. For example, in one embodiment, a method is described for automatically characterizing digitized breath sounds recorded from a subject over time as indicative of the subject being one of asleep and awake. This method comprises identify individual breathing cycles in a given segment of the recorded breath sounds; calculating one or more preset breathing cycle characteristics from the identified breathing cycles; evaluating a relative regularity of the calculated characteristics for the given segment; and upon the relative regularity satisfying a preset high regularity condition, outputting a sleep status indicator that the subject was likely asleep during the segment, otherwise outputting a wake indicator that the subject was likely awake during the segment.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: May 7, 2019
    Assignee: University Health Network
    Inventors: Hisham Alshaer, T. Douglas Bradley
  • Patent number: 10245698
    Abstract: A CNC machine shaping tool is efficiently used by monitoring human audible sound during shaping. A sound information set is created for a tool shaping a workpiece. Shaping sounds are recorded and sliced into short term units. A human operator assigns tool condition labels to each slice. Short term units are combined into mid term units. Noise is reduced by profiling. Mid term sound related features of time and frequency domains are extracted. Dimensionality is reduced by robust principal component analysis. The principal component set is balanced, e.g. by SMOTE. A classifier and principal components are selected. An information set of patterns of values of selected principal components for the tool is created. In an industrial setting, shaping sounds are recorded, noise reduced and select principal component vector values are compared to the tool condition labeled patterns of values in the information set to identify tool condition before deterioration.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: April 2, 2019
    Inventor: Hyunsoo Jeong
  • Patent number: 10238338
    Abstract: The invention provides a physiological probe that comfortably attaches to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe, which comprises a separate cradle module and sensor module, secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. The cradle module, which contains elements subject to wear, is preferably provided as a disposable unit.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: March 26, 2019
    Inventors: Devin McCombie, Gunnar Trommer, Jim Moon, Marshal Dhillon, Scott Clear, Julian Groeli
  • Patent number: 10236081
    Abstract: An electronic device includes a display, communication circuitry, at least one sensor, and a processor electrically connected with the display and the at least one sensor. The processor is configured to, based on state information obtained by the at least one sensor satisfying a predefined condition when a health state of a user corresponds to a first state, control transmitting the state information to an external server through the communication circuitry, control receiving from the external server a symptom check result corresponding to the state information, set a health state of the user to a second state based on the symptom check result, and provide a user interface (UI) for user health management at least once until the health state of the user changes from the second state to the first state based on at least one of the state information and the symptom check result.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: March 19, 2019
    Inventors: Hyun Gi Ahn, Dong Hyun Roh, Kyung Sub Min
  • Patent number: 10231692
    Abstract: An abdominal statistics system including a low profile rapidly deployable sensor element having an acoustic sensor and vibration actuator that can be conveniently attached to the abdomen of a patient. The system acquires acoustic signals as gastrointestinal (GI) sounds, processes these signals, and provides actionable data to patients and their providers.
    Type: Grant
    Filed: July 3, 2017
    Date of Patent: March 19, 2019
    Inventors: Brennan Spiegel, William Kaiser, Vincent Zegarski, Digvijay Singh
  • Patent number: 10226199
    Abstract: An information processing apparatus includes an acquisition unit, a specification unit, a determination unit, a generation unit, and a display control unit. The acquisition unit acquires a three-dimensional image containing at least a tubular structure. The specification unit specifies a first point inside the tubular structure and specifies a lesion outside the tubular structure in the three-dimensional image. The determination unit determines whether a blood vessel is present in a region between the first point and the lesion based on signal values of voxels of the three-dimensional image in the region between the first point and the lesion. The generation unit generates a two-dimensional image of the tubular structure viewed from the first point based on the three-dimensional image. The display control unit displays information indicating a region of the lesion on the two-dimensional image to be distinguishable in determining whether a blood vessel is present in the region.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: March 12, 2019
    Assignee: Canon Kabushiki Kaisha
    Inventors: Noriaki Miyake, Tsuyoshi Sakamoto
  • Patent number: 10209232
    Abstract: A CO2 detection chamber includes a gas inlet and a gas outlet. A CO2 sensor is housed in the CO2 detection chamber, where the sensor includes a reversible and selective pH-sensitive nanocomposite sensor element for CO2 detection, and a hydrophobic surface. A flowmeter, a thermistor and a humidity sensor operate to read flow and compensate for humidity conditions. A light source is coupled to receive signals from the CO2 sensor and respond to color changes in the sensor by transducing the color change into a light intensity change. A photodiode receives signals from the light source and responds to light intensity changes by transducing the light intensity changes into electronic signals representing varying degrees of light intensity. Data representing CO2 measurements is transmitted for display to a mobile device.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: February 19, 2019
    Inventors: Erica Forzani, Nongjian Tao, Di Zhao, Francis Tsow
  • Patent number: 10201386
    Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect nerve tissue such that reinnervation is inhibited. The treatment systems are capable of delivering energy to nerve tissue in a target region such that at least a portion of the nerve tissue is replaced by scar tissue or otherwise altered to inhibit reinnervation in the target region.
    Type: Grant
    Filed: October 2, 2012
    Date of Patent: February 12, 2019
    Assignee: Nuvaira, Inc.
    Inventors: Martin L. Mayse, Mark Deem
  • Patent number: 10194835
    Abstract: There is provided a method, apparatus, computer program product and wearable device for monitoring volumetric change of a lung during a breathing cycle by using an electronic signal. The method comprises: receiving by a receiver an electronic signal transmitted from a transmitter, wherein at least part of a path of the signal contours at least part of a chest wall of the lung; determining by the receiver measurements of an attribute of the signal received at the beginning and the end of a time interval during the breathing cycle; calculating by a processor a change in length of the signal path during the time interval based on the measurements of the attribute of the signal received at the beginning and the end of the time interval; and calculating by the processor a volumetric change during the time interval based on the change in signal path length.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: February 5, 2019
    Inventors: Mordechay Beyar, Oren Globerman, Zvi Reznic
  • Patent number: 10183136
    Abstract: CPAP treatment apparatus is disclosed having a controllable positive airway pressure device. A sensor generates a signal representative of patient respiratory flow that is provided to a controller. The controller is operable to determine the occurrence of an apnea from a reduction in respiratory airflow below a threshold determined from long term ventilation. When an apnea or hypopnea has occurred the calculation of the threshold is suspended until the end of that event.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: January 22, 2019
    Assignee: ResMed Limited
    Inventors: Matthew Alder, Steven Paul Farrugia, Chinmayee Somaiya
  • Patent number: 10173067
    Abstract: An implantable pacing device for delivering ventricular pacing may be configured to intermittently and variably reduce the AV delay interval used in an atrial triggered pacing mode in a manner that simulates exercise. The device may be programmed to intermittently switch to and from a variably shortened AV delay mode according to defined entry and exit conditions.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: January 8, 2019
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Allan Charles Shuros, Donald L. Hopper, Shantha Arcot-Krishnamurthy
  • Patent number: 10172548
    Abstract: Provided herein are systems, methods and devices for performing one or more titrations for oral appliance therapy. For example, a method for evaluating an outcome of oral appliance therapy in a subject is discussed herein. The method can include positioning an adjustable mandibular displacement device in an oral cavity of a subject and implementing an automatic titration protocol. The protocol can include controlling a protrusion level of the adjustable mandibular displacement device during a test period, monitoring physiological information from the subject during the test period, and analyzing the physiological information to evaluate the outcome of oral appliance therapy.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: January 8, 2019
    Assignee: ZST Holdings, Inc.
    Inventors: John Remmers, Zbigniew Ludwik Topor, Joshua Grosse, Paul Cataford, Patrick Lecoz
  • Patent number: 10168316
    Abstract: A method and apparatus for measuring endogenous CO concentration in exhaled alveolar air, comprises: proposing a method for injecting samples in small amounts, multiple times, intermittently, and establishing a CO concentration relationship between sample gas and gas in a measuring chamber; establishing a “concentration difference/electrical level difference” difference value fitting method, to obtain a fitted standard curve for a difference value between the sample gas and base gas; establishing an apparatus for measuring a CO concentration difference and a CO2 concentration difference between sample gas and base gas; proposing a method for compensating a measurement value for endogenous CO in exhaled alveolar air. The problem that the amount of sample gas in a breath test is small, and cannot completely replace the gas originally inside the measuring chamber, is solved. The effect of electrical level zero drift and residual CO of unknown concentration in cleaning gas is eliminated.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: January 1, 2019
    Assignee: Shenzhen Seekya Bio-Sci & Tech Co., Ltd.
    Inventor: Yongjian Ma
  • Patent number: 10159810
    Abstract: The present invention relates to a method and a respiration device having a respiration unit for generating an airflow for the respiration and having a monitoring unit. The monitoring unit is used to detect a respiration parameter and to classify events in the respiration on the basis of monitoring of the respiration parameter. In this case, the monitoring unit is able and designed to carry out an event analysis to recognize an occurrence, which is characteristic for Cheyne-Stokes respiration, of chronologically successive events and for this purpose to ascertain the period length thereof and to compare them to one another and to register the presence of Cheyne-Stokes respiration when the compared period lengths each deviate by less than 40% from one another.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: December 25, 2018
    Assignee: Loewenstein Medical Technology S.A.
    Inventors: Benno Doemer, Dominic Klausmann
  • Patent number: 10149621
    Abstract: A system and method for assessing treatment effects on obstructive sleep apnea are provided. The apparatus includes a bio-signal measurement unit, a combined index calculation unit, and a treatment response assessment unit. The bio-signal measurement unit measures each of the electrocardiogram and respiratory rhythm of a patient. The combined index calculation unit calculates a combined cardiac and respiratory index by combining the heart rate variability and respiratory rhythm signals measured by the bio-signal measurement unit. The treatment response assessment unit assesses a response of the patient to the treatment of obstructive sleep apnea.
    Type: Grant
    Filed: August 3, 2014
    Date of Patent: December 11, 2018
    Inventors: In-Young Yoon, Kyooseob Ha, Jae Seung Chang
  • Patent number: 10136837
    Abstract: A device and a method for the analysis of the air exhaled by a subject in order to measure basal metabolism of the subject comprise a main line for a sampling flow of the air exhaled by a subject who breathes spontaneously or a subject undergoing assisted pulmonary ventilation. A mixing mini-chamber is provided for mixing a plurality of air sampling flows exhaled by the subject within a number of respiratory cycles. Sensors for sensing the oxygen concentration and the carbon dioxide concentration respectively measure the oxygen concentration and the carbon dioxide concentration within the air flow in the main line. The device further comprises an electronic control unit which processes signals from the sensors for obtaining a measurement of metabolism of the subject within a number of respiratory cycles.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: November 27, 2018
    Assignee: COSMED S.r.l.
    Inventors: Paolo Brugnoli, Alberto Di Pietro, Marco Ragusa, Domenico Celentano
  • Patent number: 10112022
    Abstract: A feature implemented in a CPAP breathing therapy machine to determine if the patient is suffering from a flow limitation condition and if so, altering the operation of the CPAP machine to attempt to alleviate the condition.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: October 30, 2018
    Assignee: DeVilbiss Healthcare LLC
    Inventors: Michael B Knepper, Jeffrey J Lauer
  • Patent number: 10086204
    Abstract: Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: October 2, 2018
    Inventors: Warren M. Grill, Jr., Alan D. Dorval, II