Injectors/holders For Seeds Or Implants (e.g., Capsules) Patents (Class 600/7)
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Publication number: 20080300446Abstract: An assembler which limits the amount of torque that may be applied to a brachytherapy cartridge magazine when its cap is threaded onto same. The assembler is constructed so that the brachytherapy cartridge will rotate within the assembler before a destructive torque is applied while the cap and cartridge magazine are screwed together.Type: ApplicationFiled: December 15, 2006Publication date: December 4, 2008Inventors: Kevin Helle, Jay Reed
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Publication number: 20080269539Abstract: A brachytherapy device for treating tissue within a cavity of a body. The device may include a first set of tubes configured to be inserted into the cavity through an opening at the surface of the body. Each of the tubes may have an external end and an interior channel beginning at the external end that is configured to receive radioactive material. The external ends of the tubes may be bundled together. The tubes may be of a length that causes the external ends to be near the opening in the surface of the body while the tubes are in the cavity. A seal may be configured to prevent fluid that originates from the cavity from entering into the external ends of the tubes while they are near the opening in the surface of the body. The seal may include a gasket that is pressed against the external ends of the tubes. The gasket may have openings that align with channels within the external ends of the tubes.Type: ApplicationFiled: April 27, 2007Publication date: October 30, 2008Inventors: L. Michael Cutrer, Leigh Spotten, Joseph Wong, Fredrick Winch
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Publication number: 20080269540Abstract: Provided herein are adaptors that enable a seed cartridge that is configured to be used with a first type of needle having a locking hub to instead be used with a second type of needle having a cylindrical hub. Such a seed cartridge has a hub at its distal end that is configured to attach to the locking hub of the first type of needle. The adaptor includes a proximal portion configured to removably attach (and in specific embodiments lock) to the hub at the distal end of the seed cartridge. The adaptor also includes a distal portion configured to removably attach to the cylindrical hub of the second type of needle. A central portion of the adaptor connects the proximal and distal portions of the adaptor. A bore extends through the adaptor and allows seeds and optional spacers to be transferred from the seed cartridge into a hollow cannula of the second type of needle. Also provided herein are methods for using such adaptors.Type: ApplicationFiled: April 25, 2008Publication date: October 30, 2008Applicant: WORLDWIDE MEDICAL TECHNOLOGIES LLCInventor: Gary A. Lamoureux
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Patent number: 7429240Abstract: The present invention provides devices for depositing objects into tissue of an animal. The devices include a cannula having a proximal-end and an opposite distal end insertable into tissue and defining an exit aperture. The cannula has a sidewall between the distal and proximal ends and defines a passageway in communication with the exit aperture. A distal retaining tab extends from an inner surface of the cannula and is positioned across at least a portion of the passageway adjacent the exit aperture. The distal tab has a first closed position blocking the passageway and a second open position wherein the tab is urged towards the sidewall to allow an object to pass. The tab is resilient to return to the first position after the object passes the tab. In some embodiments, the invention also includes a proximal retaining tab adjacent the proximal end of the cannula and positionable to block a portion of the passageway.Type: GrantFiled: August 22, 2006Date of Patent: September 30, 2008Assignee: Promex Technologies, LLCInventor: Michael E Miller
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Patent number: 7425195Abstract: Radiation shielding devices are provided herein. In particular, the devices provided herein can be adapted to shield radiation emitted by one or more radioactive brachytherapy seeds contained within, for example, a vial or a cartridge.Type: GrantFiled: August 13, 2004Date of Patent: September 16, 2008Assignee: Core Oncology, Inc.Inventors: Lawrence Y. Wissman, Jerry R. Barber
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Publication number: 20080221384Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.Type: ApplicationFiled: June 1, 2007Publication date: September 11, 2008Applicant: Cianna Medical, Inc.Inventors: Eduardo Chi Sing, George D. Hermann, Doug S. Sutton, Tommy G. Nguyen, Mark A. Ritchart, Steven L. Gex
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Publication number: 20080207982Abstract: A selectively loadable/sealable bioresorbable carrier assembly for retaining and positioning elements used in brachytherapy procedures comprises a bioresorbable tube having a closed distal end and a proximal open end. The bioresorbable tube is loaded with a selectable arrangement of elements, including at least one radioactive seed, through the proximal open end. After the bioresorbable tube is selectably loaded, the bioresorbable tube is heat sealed at a sealing position adjacent a proximalmost element. Once sealed, the bioresorbable tube maintains the arrangement of elements throughout the treatment duration.Type: ApplicationFiled: February 21, 2008Publication date: August 28, 2008Applicant: CORE ONCOLOGY, INC.Inventors: Daniel M. Elliott, George M. Hoedeman, John J. Berkey
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Publication number: 20080188705Abstract: Devices and methods are provided for controlled application of a treatment to tissue adjacent a body cavity, such as after removal of tissue, e.g. cancer. A device embodying features of the invention includes one or more radiation shielding components to control emitted radiation from a radiation source to minimize radiation damage to healthy portions of the body cavity. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location therein to seal the passageway leading to the body cavity. Methods for treating a body cavity include methods for delivering a radiation source to a body cavity while minimizing damaging irradiation of healthy tissue.Type: ApplicationFiled: January 31, 2008Publication date: August 7, 2008Inventors: Paul Lubock, Michael L. Jones
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Publication number: 20080183028Abstract: The present invention relates to an arthroscopy apparatus, comprising at least three elements selected from: a conventional arthroscopic lens (12), to which there is coupled a power supply device or capsule, in the inside of which is the power source (1), and a miniature camera (8), characterized by not comprising connecting cables.Type: ApplicationFiled: January 15, 2008Publication date: July 31, 2008Inventors: Pedro Guillen Garcia, Antonio Lopez Hidalgo, Marta Guillen Vicente, Jesus Lopez Hidalgo, Miguel Angel Lopez Hidalgo, Isabel Guillen Vicente
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Publication number: 20080177127Abstract: A brachytherapy treatment device includes at least one tubular insertion member, an expandable member, and means for deflecting the at least one tubular insertion member. The tubular insertion member has a longitudinal axis and proximal and distal ends. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. The distal end of the at least one deflected tubular insertion member within the first expandable member is offset from the longitudinal axis when deflected. The at least one deflected tubular insertion member is configured to receive a radiation source to position a radiation source offset with regard to the longitudinal axis to form an asymmetric radiation dosing profile. Additional brachytherapy treatment devices and methods for forming an asymmetric radiation dosing profile are disclosed.Type: ApplicationFiled: December 18, 2007Publication date: July 24, 2008Inventors: Donna Allan, Greg Amante, Risa Anav, Maria Benson, Michael Crocker, Gregory K. Edmundson, Friedrick Ho, Robert Kotmel, Glenn Magnuson, Gregory T. Martin, Walter Ocampo, Mukund Patel, F. Mark Payne, Russel Sampson, Jessica Schenck, James Stubbs, Moshe Zilversmit
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Publication number: 20080161635Abstract: A cartridge may include a housing configured to contain a plurality of like items and a track inside the housing. The track extends in a first direction, and a plunger may be slidable along the track in the first direction and configured to urge the items toward a first end of the housing. The cartridge may include a gate attached to the housing. The gate may be movable between a first position preventing the items from being removed from the housing and a second position allowing one of the items to he removed from the housing. The gate may be configured to remove the one item from being urged by the plunger.Type: ApplicationFiled: June 29, 2007Publication date: July 3, 2008Inventors: Breese J. Watson, Michael W. Drobnik, Jeffrey Neaves, Robert Brownell, Erick Rios
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Publication number: 20080154086Abstract: An interstitial brachytherapy apparatus and method for delivering and monitoring radioactive emissions delivered to tissue surrounding a resected tissue cavity. The brachytherapy device including a catheter body member having a proximal end, a distal end, and an outer spatial volume disposed proximate to the distal end of the body member. A radiation source is disposed in the outer spatial volume and a treatment feedback sensor is provided on the device. In use, the treatment feedback sensor can measure the radiation dose delivered from the radiation source.Type: ApplicationFiled: March 11, 2008Publication date: June 26, 2008Inventor: James B. Stubbs
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Publication number: 20080146863Abstract: An internal radiation therapy device including concentric inner and outer tubes with the inner tube being inflexible and an isotope tube extending into the inner tube and being filled with a radioisotope through an isotope tube or x-ray source and the outer flexible tube filled through a filler tube with a material having radiation characteristics similar to human tissue.Type: ApplicationFiled: February 22, 2008Publication date: June 19, 2008Inventor: Gary B. Stillwagon
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Publication number: 20080146862Abstract: A brachytherapy device may include a plurality of rods, each configured to move between a straightened position and a bowed position, the plurality of rods configured to collectively form a shaft while each rod is in the straightened position and to collectively form at least one cage while at least some of the rods are in the bowed position, at least some of the rods having lumens that are configured to receive and hold radioactive material. A brachytherapy device may further include a rotatable mechanism configured to cause at least some of the plurality of rods to move between the straightened position and the bowed position upon rotation of the rotatable mechanism.Type: ApplicationFiled: November 5, 2007Publication date: June 19, 2008Inventors: L. Michael CUTRER, Frederick WINTCH, Richard A. TERWILLIGER, John ZHANG, David BOSSI
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Patent number: 7381178Abstract: A radiotherapy system, and preferably a brachytherapy system, for delivering radiation to tissue surrounding an interstitial space is provided. While the system can be used for a variety of purposes, the system is preferably used to treat spinal metastases. In general, the system includes a catheter member having a proximal end, a distal end, and an inner lumen extending therethrough, and a structural support adapted to fit within an interstitial space in load bearing portion of a patient's body and having an internal space for removably receiving the distal end of the catheter member. At least one anchoring element can be disposed proximate to the distal end of the catheter. The anchoring element is preferably adapted to fit within the internal space in the structural support so as to anchor the distal end of the catheter therein.Type: GrantFiled: October 27, 2005Date of Patent: June 3, 2008Assignee: Cytyc CorporationInventors: Rance A. Winkler, Timothy J. Patrick, Carribeth B. Ramey
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Publication number: 20080125760Abstract: An anchoring mechanism and method for anchoring a device within a biological conduit include an expandable element configured for retaining the device at a desired angle relative to a central axis of the biological conduit. A steering mechanism is preferably provided for orienting the device prior to operation of the anchoring mechanism. The anchoring mechanism and method are employed in drug delivery devices, brachytherapy devices or for anchoring a catheter or sheath to provide a working channel for reliable guidance of a wide range of tools to a target location within the body.Type: ApplicationFiled: February 9, 2005Publication date: May 29, 2008Applicant: Super Dimension Ltd.Inventor: Pinhas Gilboa
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Publication number: 20080119687Abstract: A source guide apparatus for brachytherapy application, wherein the source guide apparatus is provided with a source capsule, a guidewire for moving the source capsule through a catheter, a mechanical connection between the guidewire and the source capsule, wherein the source guide apparatus is provided with a sleeve which is attached on the capsule, wherein the sleeve envelops at least a part of the mechanical connection.Type: ApplicationFiled: October 22, 2007Publication date: May 22, 2008Applicant: Isodose Control Intellectual Property B.V.Inventors: Eric van't Hooft, Libbe van Zwol
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Publication number: 20080108859Abstract: A brachytherapy device may include an expandable outer cage, an expandable inner cage positioned within the outer cage and configured to receive radioactive material at its perimeter, and a movable actuator configured to cause the outer and inner cages to expand simultaneously in response to movement of the actuator between certain positions while maintaining a substantially constant separation distance between the outer and inner cages.Type: ApplicationFiled: April 18, 2007Publication date: May 8, 2008Inventors: L. Michael Cutrer, Richard A. Terwilliger, Joe Wong, Fredrick Winch
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Publication number: 20080097139Abstract: A system for treating lung tissue includes a tube having a distal end, an anchoring device secured to the tube, the anchoring device configured to anchor at least a portion of the tube against an esophagus, a trachea, or a bronchus; and an ablation device carried within a lumen of the tube.Type: ApplicationFiled: July 14, 2006Publication date: April 24, 2008Applicant: Boston Scientific Scimed, Inc.Inventors: Claude Clerc, Paul M. Scopton, Isaac Ostrovsky, Harold M. Martins, Stephen J. Perry
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Patent number: 7361135Abstract: A delivery system for interstitial radiation therapy that uses a brachytherapy needle assembly for simultaneously dispensing an effective amount of medicine, such as anti-inflammatory agents, along with radioactive seeds. Medicine can be stored in and dispensed from a reservoir attached to a needle hub or to a stylet handle or it can be injected into the needle via a three-way fitting. Alternatively, medication can be added directly to the needle cannula. Additionally, the brachytherapy needle or the radioactive seeds and spacers can be coated with medication that would be absorbed by the body upon implantation.Type: GrantFiled: August 24, 2004Date of Patent: April 22, 2008Assignee: C R Bard, IncInventors: Christopher D. Drobnik, Michael W. Drobnik
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Patent number: 7338430Abstract: A vaginal brachytherapy applicator is versatile to different anatomies and more comfortable to the patient than prior applicators. An inflatable balloon on a shaft may be inelastic or elastic. In one embodiment the shaft is rotatable relative to the balloon for enabling a ring or band of dose delivery, for versatility in radiation placement. Alternatively, the source can be rotated and pulled back within a stationary shaft. An adjustment is provided for reducing the length of balloon that inflates, to accommodate different anatomies and positions. Although isotope radiation sources can be used in the applicator, an electronic source is preferred, and the system and method include procedures for using the applicator with an electronic source.Type: GrantFiled: December 30, 2005Date of Patent: March 4, 2008Assignee: Xoft, Inc.Inventors: Alex Lim, Paul A. Lovoi, Heike Hausen, Daren L. Stewart
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Patent number: 7335155Abstract: An apparatus for delivering a formulation into a body in integer amounts includes a cannula with an insertion end for insertion into the body. The cannula includes a channel such as a tube to store the formulation. A rod is inserted into an end of the cannula opposite the insertion end; the rod has one end to contact the formulation and another end. The actuator controllably moves the rod through the tube of the cannula to deliver the formulation through the insertion end of the cannula.Type: GrantFiled: September 14, 2004Date of Patent: February 26, 2008Assignee: Boston Scientific Scimed, Inc.Inventor: Michael S. H. Chu
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Publication number: 20080004481Abstract: An apparatus and method for the insertion of a medical tool, for example a needle, within the human body. The apparatus and method are particularly useful in prostate brachytherapy and in prostate biopsy. The apparatus comprises a telescoping guide universally coupled to a first and second positioning means that are used to automatically and/or manually position the guide at a desired needle insertion trajectory. Automatic positioning of the guide is accomplished with reference to three-dimensional transrectal ultrasound images that can also be used to show needle insertion in real-time. The apparatus may be manually positioned in the approximate insertion trajectory and then a computer interconnected with the apparatus may be used to achieve the final trajectory based upon the ultrasound images. The apparatus is particularly useful in cases where multiple needles are to be inserted into a small target area and in cases where pubic arch interference prevents direct access to the target area.Type: ApplicationFiled: June 28, 2006Publication date: January 3, 2008Inventors: Jeffrey Bax, Aaron Fenster, Jacques Montreuil, Lori Gardi, David Martin Smith
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Patent number: 7311655Abstract: The invention relates to a method for producing a radioactive brachytherapy source material comprising indium-114m in radioactive equilibrium with indium-114 as main radioactive isotopes. A new radioactive brachytherapy source material comprises indium-114m in radioactive equilibrium with indium-114 as main radioactive isotopes. A new encapsulated radioactive brachytherapy source comprises the new radioactive brachytherapy source material.Type: GrantFiled: March 17, 2003Date of Patent: December 25, 2007Assignee: Nucletron B.V.Inventor: Dennis Robert Schaart
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Patent number: 7306557Abstract: The invention relates to a device for image guided automated insertion of an elongated an elongated hollow needle to a desired location in an animal body for effecting radiation therapy of cancerous tissue in said body comprising needle positioning means for positioning said needle having a distal end and a proximal end relative to said desired location; needle drive means for driving said needle with its distal end towards said desired location; and real time imaging means for creating and presenting an image of said desired location and the position of the distal end of said needle during insertion of said needle. It is an object of the invention to provide a device for inserting a needle in an animal body, wherein a better access to the treatment site in the patient's body is obtained thus improving the possibilities in configuring a treatment plan for said patient and wherein the patient is suffering lesser trauma, bleeding and discomfort.Type: GrantFiled: December 5, 2003Date of Patent: December 11, 2007Assignee: Nucletron B.V.Inventors: Jan Jacob Wouter Lagendijk, Marinus Adriaan Moerland
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Publication number: 20070282155Abstract: A seed-holding device comprises of a transfer device having a main body and a pusher. The device also includes a holder for engaging the transfer device; the transfer device has a closed proximal end, an open distal end, an expansive spring, and a pusher connecting means. The expansive spring is located between the closed proximal end and the pusher connecting means. The seed-holding device, when loaded, has no parts that can be easily broken by extending beyond the proximal end of the transfer device.Type: ApplicationFiled: June 6, 2006Publication date: December 6, 2007Inventors: Rohit Mehta, Markus Muehlheim
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Publication number: 20070265488Abstract: In one embodiment an after-loader for providing an implant to a hollow needle, the after-loader comprising a body having a distal end including a bevel for receiving a hub of a seed lock needle, and a bore therethrough for receiving a hub of a MICK® needle; a proximal end having a funnel shaped opening; a shield adapted to be provided over the body; and wherein the distal end further includes a taper along a portion of a distance from the distal end to the proximal end for providing a friction fit to a shield. This abstract is not intended to be a complete description of the invention.Type: ApplicationFiled: November 3, 2006Publication date: November 15, 2007Applicant: Worldwide Medical Technologies LLCInventors: Gary A. Lamoureux, Warren W. Johnston
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Publication number: 20070265487Abstract: In one embodiment an applicator includes a needle receiver adapted to be removably mateable with a needle positioned at the surgical site, a housing adapted to receive a push rod, and a clip for receiving one or more implants, the clip having a plurality of ports adapted to bridge the needle receiver and the housing so that the needle receiver can receive the push rod, wherein the clip can be rotatably repositioned so that the plurality of ports can selectively bridge the needle receiver and the housing. This abstract is not intended to be a complete description of the invention.Type: ApplicationFiled: November 3, 2006Publication date: November 15, 2007Applicant: WORLDWIDE MEDICAL TECHNOLOGIES LLCInventors: Gary A. Lamoureux, Warren W. Johnston
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Publication number: 20070265486Abstract: A catheter needle, for irradiating tumors, formed by an elongated plastic tube with parts partly unfoldable outwards which can lock themselves in the tissue, and a closed end. The closed end has a reinforced sharp pointed shape with which tissue can be punctured. In the improved version, therefore, a point from a harder material is provided which is provided in or around the plastic so that the catheter needle has sufficient sharpness like a conventional metal needle. Thus, the catheter needle can puncture the skin and harder, deeper-lying tissues directly without pre-puncturing or other aids.Type: ApplicationFiled: July 13, 2006Publication date: November 15, 2007Applicant: Isodose Control Intellectual Property B.V.Inventor: Eric van 't Hooft
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Patent number: 7282020Abstract: Systems, apparatus, components and methods are disclosed that allow the clinician to circumvent the pubic arch in instances where it interferes with insertion of instrumentation into the prostate or periprostatic tissue. The systems, apparatus and components disclosed herein employ structures, such as needles and trocars, of shape memory alloys, such as nickel-titanium (Ni—Ti) for the purpose of avoiding the pubic arch when accessing the prostate from the perineum.Type: GrantFiled: April 22, 2002Date of Patent: October 16, 2007Assignee: Microspherix LLCInventor: Edward J. Kaplan
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Patent number: 7267643Abstract: The invention relates to a method and apparatus for temporarily inserting and positioning at least one energy emitting source in an animal body, wherein the apparatus comprises at least: a hollow open needle having a proximal needle end and a distal needle end to be inserted into the body, so as to provide a channel in the body; a guide tube having a proximal guide tube end and a distal guide tube end to be inserted into the hollow open needle; the hollow open needle being retractable from the body over the guide tube; a first fixing element for fixating the guide tube with said proximal guide tube end relative to the body; a catheter tube having a closed distal catheter tube end and an open proximal catheter tube end to be inserted with its distal catheter tube end until a predetermined depth into the guide tube and the body via said proximal guide tube end and fixating the catheter tube to the guide tube; at least one energy emitting source for insertion into the catheter tube via said proximal catheter tubType: GrantFiled: June 3, 2003Date of Patent: September 11, 2007Assignee: Nucletron B.V.Inventors: Albert Dirk Adrianus Koster, Frits Van Krieken, Hans Martin Schot
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Patent number: 7265199Abstract: The present invention relates to an anti-thrombogenic, physically well-tolerated polymer and its use for manufacturing sheaths and films as a component of therapeutic devices for preventing excessive cell proliferation. Furthermore, it relates to films made from the polymer as well as wrappings for medical devices such as stents. It also relates to medical devices that are enclosed by a film or wrapping according to the invention.Type: GrantFiled: April 10, 2001Date of Patent: September 4, 2007Assignee: Celonova BioSciences Germany GmbHInventors: Michael Grunze, Claudia Gries
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Patent number: 7247160Abstract: Apparatuses and methods for percutaneously implanting objects, such as radioactive seeds or markers, in patients. In one embodiment, a device for percutaneously implanting an object in a patient includes a handle, a cannula projecting outwardly from the handle, and an actuator movably disposed relative to the handle. In one aspect of this embodiment, the cannula can be configured to releasably hold the object and percutaneously penetrate the patient. In another aspect of this embodiment, the actuator can be operably connected to the cannula and operable to move the cannula relative to the handle and release the object within the patient. In a further aspect of this embodiment, the cannula can include a tip portion having a restriction configured to releasably hold the object for implantation in the patient.Type: GrantFiled: December 30, 2002Date of Patent: July 24, 2007Assignee: Calypso Medical Technologies, Inc.Inventors: Keith Seiler, Eric Hadford
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Publication number: 20070142694Abstract: The present disclosure provides a brachytherapy apparatus that delivers a low dose, partial breast irradiation treatment for post-lumpectomy patients via introduction of a catheter-like device through a cannula. The apparatus may be introduced post-surgically with local anesthesia under image guidance into the previous excision site and into a cavity by a surgeon. The brachytherapy apparatus includes a seed containment device configured to contain a plurality of low-dose radioactive seeds therein. The seed containment device may be one or more thin-walled tubes. The apparatus is further configured to expand so that at least a portion of the seed containment device is positioned against the remaining tissue and the plurality of radioactive seeds are disposed at the perimeter of the seed containment device. Also described are various clamps for the apparatus, and sleeves for adjusting the size of the device to fit a cavity when the apparatus is in use.Type: ApplicationFiled: December 16, 2005Publication date: June 21, 2007Inventors: L. Michael Cutrer, Richard A. Terwilliger, Fredrick Winch, John Zhang, Wayne Higgins, Terence Ellard, David Bossi
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Patent number: 7229417Abstract: Implantable devices and methods of use are disclosed for marking the location of a biopsy or surgery for the purpose of identification. The methods include providing a biodegradable radiodense implant and taking a tissue sample from a biopsy site within a breast of a patient. The biodegradable implant is then positioned at the biopsy site. The tissue sample is tested and the biopsy site is then relocated. In one embodiment, the entire implant is radiodense. In another embodiment, the entire implant is biodegradable. Methods of using a biodegradable implant having a radiodense material and a biodegradable implant that is visible using an imaging system are also included.Type: GrantFiled: October 15, 2004Date of Patent: June 12, 2007Assignee: Ethicon Endo-Surgery, Inc.Inventors: Seth A. Foerster, Fred H. Burbank, Mark A. Ritchart, Elias A. Zerbouni
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Patent number: 7229401Abstract: The invention relates to a device and method for inserting a needle in an animal body for effecting radiation therapy in the body, including a template for positioning the needles to be inserted, needle drive structure for drive a needle through said template towards a desired location in the body, and real-time imaging structure for creating and presenting an image of the desired location and the position of said needle during the insertion of said needle. Due to the fact that the bevelled tip of a hollow needle cause the needle to diverge away from the “line of insertion or movement” and away from the actual desired position in the animal body adversely affecting the dosimetry quality of the implanted seeds a more accurate insertion of the needle is required. According to the invention the device is provided with adjusting structure for adjusting a movement of said needle towards said desired location during insertion.Type: GrantFiled: November 22, 2002Date of Patent: June 12, 2007Assignee: Nucletron B. V.Inventor: Johann Kindlein
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Patent number: 7223226Abstract: Needles and methods of plugging a needle having a tip opening with an inside diameter and a needle tip length, wherein the methods generally comprise the steps of, providing a plug material having a predetermined viscosity; providing a delivery device for introducing the plug material into the needle tip opening, wherein the delivery device comprises a delivery tube having a delivery diameter that is equal to or less than the inner diameter of the needle tip opening; introducing at least a portion of the heated plug material into the needle tip opening via the delivery tube.Type: GrantFiled: November 4, 2005Date of Patent: May 29, 2007Assignee: Nuclear Consultants Group, Inc.Inventor: Anthony Biscotti
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Patent number: 7201715Abstract: A method and system for monitoring loading of radiation into an insertion device for use in a radiation therapy treatment to determine whether the treatment will be in agreement with a radiation therapy plan. In a preferred embodiment, optical sensors and radiation sensors are used to monitor loading of radioactive seeds and spacers into a needle as part of a prostate brachytherapy treatment.Type: GrantFiled: December 23, 2002Date of Patent: April 10, 2007Assignee: Computerized Medical Systems, Inc.Inventors: Everette C. Burdette, Bruce M. Komandina
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Patent number: 7199375Abstract: An apparatus in one example comprises a vial that comprises a vial bottom and a vial cap that connect to enclose one or more radioactive seeds; and a radiation shielding container that comprises a bottom portion and a top portion that connect to enclose the vial. The radiation shielding container and the vial comprise one or more vents for movement of a sterilant therethrough for sterilization of the one or more radioactive seeds within the vial. The bottom portion of the radiation shielding container comprises a structure that engages the vial bottom to prevent rotational movement of the vial bottom during removal of the vial cap.Type: GrantFiled: October 12, 2004Date of Patent: April 3, 2007Assignee: Bard Brachytherapy, Inc.Inventors: Christopher D. Drobnik, Michael W. Drobnik
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Patent number: 7171255Abstract: A method and apparatus for three-dimensional imaging and treatment of a patient's body. The method and apparatus utilize a system for developing a therapy plan for treatment of an organ of the patient, a device for generating ultrasound image data from a treatment region and a device for providing a translucent volume image of a portion of a patient's body and a separate translucent image of the patient organ and a three dimensional viewing device to superimpose a translucent article image to enable viewing of the article image simultaneously with the patient organ and a portion of the patient's body.Type: GrantFiled: July 2, 2001Date of Patent: January 30, 2007Assignee: Computerized Medical Systems, Inc.Inventors: Edward J. Holupka, Everette C. Burdette, Irving D. Kaplan
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Patent number: 7150709Abstract: A seeding needle lumen is adapted to receive a string of seeds and spacers. A dimple is formed in the seeding needle near its distal end and a protuberance formed by the dimple extends into the lumen. A hollow housing formed of a bio-absorbable, flexible and resilient material is positioned within the lumen in abutting relation to a trailing end of the protuberance. The hollow housing has an external diameter slightly less than a diameter of the lumen so that the hollow housing cannot slide past the protuberance and an internal diameter adapted to slidingly receive a seed or spacer positioned at a leading end of a string. The flexible and resilient material is momentarily deformable so that the hollow housing may squeeze past said protuberance when a stylet is maintained in a fixed position in abutting relation to a trailing end of the seeds and spacers when the seeding needle is withdrawn.Type: GrantFiled: December 24, 2004Date of Patent: December 19, 2006Inventors: Bruno Schmidt, Robert McKenzie
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Patent number: 7131942Abstract: Disclosed is a brachytherapy seed deployment system, for use in any of a variety of medical procedures such as radiation treatment of the prostate gland. The system includes a number of brachytherapy seed deployment needles, each preloaded with brachytherapy seeds in patterns and activities predetermined for a unique patient. The seeds are contained in transparent tubular sleeves, thereby allowing direct visualization of the brachytherapy seeds and spacers, so that the seed pattern may be inspected at the clinical site. A releasable retainer prevents accidental brachytherapy seed loss. The system additionally includes shipping containers, separately accessible calibration seeds and a display stand for use at the clinical site. Methods are also disclosed.Type: GrantFiled: March 11, 2003Date of Patent: November 7, 2006Assignee: C. R. Bard, Inc.Inventors: John Taylor, Michael J. Ko
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Patent number: 7104945Abstract: The present invention provides devices for depositing objects into tissue of an animal. The devices include a cannula having a proximal end and an opposite distal end insertable into tissue and defining an exit aperture. The cannula has a sidewall between the distal and proximal ends and defines a passageway in communication with the exit aperture. A distal retaining tab extends from an inner surface of the cannula and is positioned across at least a portion of the passageway adjacent the exit aperture. The distal tab has a first closed position blocking the passageway and a second open position wherein the tab is urged towards the sidewall to allow an object to pass. The tab is resilient to return to the first position after the object passes the tab. In some embodiments, the invention also includes a proximal retaining tab adjacent the proximal end of the cannula and positionable to block a portion of the passageway.Type: GrantFiled: November 9, 2004Date of Patent: September 12, 2006Assignee: Promex Technologies, LLCInventor: Michael E. Miller
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Patent number: 7101333Abstract: Methods and apparatus are provided for loading therapeutic materials into brachytherapy needles. The apparatus comprises a loading tube with a lumen and two transverse slots, and radioactive seed and spacer cartridges slidably received within the transverse slots. The apparatus may be used in conjunction with a standard brachytherapy plunger and needle coupled to, respectively, the proximal and distal ends of the loading tube. The plunger dislodges seeds and spacers from the cartridge chambers to load the needle with a predetermined packing arrangement.Type: GrantFiled: October 23, 2003Date of Patent: September 5, 2006Inventors: Thomas C. Green, Michael J. Horzewski, Jason Klofstad
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Patent number: 7097609Abstract: The invention relates to an after loader apparatus for treatment of tumours in an animal body comprising a housing with at least one exchangeable radiation source connected to a first end of a transport wire, which wire is connected with its other end to transport means for advancing said transport wire and said radiation source through a guide tube to and from a tumour in said body, where at least the radiation source and the transport wire are mounted in an exchangeable radiation shielded after loader cartridge, which cartridge can be placed in a suitable receptable opening present in said housing.Type: GrantFiled: March 7, 2003Date of Patent: August 29, 2006Assignee: Nucletron B.V.Inventors: Johann Kindlein, Frits van Krieken, Arie Luite Visscher
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Patent number: 7066873Abstract: A transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device comprises an integral pump for pressurizing and circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge is provided including a reservoir from which fluid is drawn by the pump and into which fluid is returned after being circulated through the fluid path. The pump may be a peristaltic pump and the fluid cartridge may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge may be of a radiation-blocking material, such as quartz.Type: GrantFiled: October 27, 2003Date of Patent: June 27, 2006Assignee: Best Vascular, Inc.Inventors: James D. Hughett, Robert Michael Webster, Douglas Layland Armstrong, Byron Lee Boylston, Gregg T. Juett, Richard A. Hillstead, Jack C. Griffis, III, Andrew L. Lerohl, Mark Dehdashtian, Marvin A. Guiles
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Patent number: 7066872Abstract: Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the vascular system of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's vascular system. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.Type: GrantFiled: April 11, 2003Date of Patent: June 27, 2006Assignee: Best Vascular, Inc.Inventors: Ron Waksman, Thomas D. Weldon, Richard A. Hillstead, Jonathan J. Rosen, Charles E. Larsen, Ian R. Crocker, Raphael F. Meloul
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Patent number: 7063681Abstract: An implant retention trocar includes a cannula for puncturing the skin of an animal and an obturator for delivering the implant beneath the skin of the animal. The implant retention trocar has a cannula distal tip design which causes a minimum of trama and tearing of tissue during implant insertion. A spring element received within the cannula prevents an implant which is to be inserted into an animal from falling out of the cannula during the implant insertion process. The spring element includes a longitudinal leg which is folded with a zig-zag shaped bend. When the spring element is inserted into the cannula the zig-zag shaped bend of the longitudinal leg retains the implant within the cannula.Type: GrantFiled: April 23, 1999Date of Patent: June 20, 2006Assignee: Alza CorporationInventor: John R. Peery
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Patent number: 7060020Abstract: A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated member made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the member. The delivery system and method further customize the member based on a prescription.Type: GrantFiled: December 28, 2001Date of Patent: June 13, 2006Assignee: IdeaMatrix, Inc.Inventors: Richard A. Terwilliger, Gary A. Lamoureux
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Patent number: 7041046Abstract: The present invention provides improved devices, methods, and kits for inhibiting restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides controlled immunomodulator delivery in combination with ionizing radiation to selected locations within a patient's vasculature to reduce and/or inhibit restenosis and hyperplasia rates with increased efficacy. In one embodiment, the combination radiation and immunomodulator delivery catheter for inhibiting hyperplasia comprises a catheter body having a proximal end and distal end, an ionizing radiation source coupleable to the catheter body for applying a radiation dose to a body lumen, and a porous material, matrix, membrane, barrier, coating, infusion lumen, stent, graft, or reservoir for releasing an immunomodulator to the body lumen.Type: GrantFiled: May 7, 2001Date of Patent: May 9, 2006Assignee: Xoft, Inc.Inventor: Michael R. Forman