Abstract: A dressing having a flexible sleeve shaped to accommodate a substantially cylindrical body or plant portion, the sleeve having a lining which is substantially non-adherent to the body or plant part being bandaged and having a peripheral securement means which attaches two peripheral portions to each other without those portions being circumferentially adhered to the sleeve portion.

Abstract: Described is a method of supplying an active ingredient to a location beneath the outer layer of skin or into soft tissue which includes the steps of providing a polymer-containing liquid comprising an active ingredient; subjecting the liquid issuing from an outlet to an electric field to cause the liquid to form at least one electrically charged jet that breaks up to provide charged fiber fragments or fibrils containing an active ingredient, the fiber fragments or fibrils being capable of sticking onto the outer layer of skin or soft tissue to supply the active ingredient beneath the outer layer of skin or soft tissue; and contacting skin with the fiber fragments or fibrils.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: An apparatus for cleansing wounds, in which wound exudate is removed from a wound bed and selectively cleansed and returned to the wound. The cleansing means removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The associated wound dressing and cleansing means are conformable to the wound, and may have irrigant fluid circulated from a reservoir by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing.

Abstract: The present invention provides a multilayer bandage, having a webbing for contacting a wound and a first membrane that has at least one water-insoluble polymer and is water-impervious. The present invention further provides methods for making the multilayer bandage, methods of using the multilayer bandage for accelerated wound healing, and kits having compositions of the present invention.

Abstract: A lightweight, flexible, aerating, compressive, thermal material. Perforations allow the treatment area to aerate. Thermal capacity of the invention allows for hot or cold treatment in a manner that compressively supports the object undergoing thermal treatment while maintaining maximum mobility. The material is made from an elastomer such as polyurethane with the addition of silicon and vegetable oil. Resin is used to color the product.

Abstract: Assemblies for the adhesive attachment to the skin or mucosa of a host are disclosed. The assembly or transdermal patch includes an outer backing layer, a first layer of adhesive on the inner surface of the outer backing layer, an inner backing layer, and an intermediate release liner between the first layer of adhesive and the inner backing layer. The intermediate release liner includes a releasable surface on both its inner and outer surfaces.

Abstract: The present invention relates to a support system particularly intended for treatment and prevention of diseases of venous origin, characterized in that it comprises a first support layer, which is composed of an elastic band attached across its entire surface to an absorbent layer, and a second support layer, which is a self-adhesive elastic band. This support system has a dynamic coefficient of elasticity of between 5 and 55 Newton/cm.

Abstract: An abdominal wound dressing and methods of use are described that enable the application of negative pressure to the wound site in a healing manner while also limiting the formation of adhesions that would prevent the removal of the dressing. The dressing comprises a layer of porous foam material enclosed by sheets of elastomeric material punctuated by a number of appropriately placed holes. Multiple layers of porous foam may also be used. A suction tube connector is provided on an upper surface of a layer of foam for connection to a negative pressure source. At least one layer of foam is enclosed in elastomeric material and is placed in direct contact with the tissue within the open wound. Fluids are drawn by negative pressure through the holes positioned in the elastomeric envelope and through the foam.

Abstract: A layered adhesive construct is provided having a backing layer, a first layer of a hydrocolloid adhesive, and a second layer of a hydrocolloid adhesive, where the first and second layers of hydrocolloid adhesives have different composition, and the second layer of hydrocolloid adhesive is interposed between the first layer of hydrocolloid adhesive and the backing layer. The first adhesive layer is a layer of moldable adhesive paste including hydrocolloids having a Strain Recovery below 45% and the second adhesive layer is a layer of hydrocolloid adhesive having a Strain Recovery above 55%.

Abstract: A nipple reconstruction device includes a core component having a substantially circular hollow opening therein for receiving a person's nipple; padding attached to a lower part of the core and substantially lining the lower part of the core and at least a portion of the hollow opening in the core, and an attaching component constructed and adapted to hold the device in place on the person's skin. The core may be a semi-rigid, pliable, high durometer material. The padding may be gauze, woven rayon cellulose, cotton, a cotton/polyester blend material; or a non-woven, one-sided medical tape. The attaching component may be an adhesive tape having a plurality of tabs for holding the device in place on the person's skin.

Abstract: A tear and fatigue resistant gels, gel composites, and gel articles including collapsible articles having two or more communicating internal volumes like cavities when depressed by external pressure or force is capable of collapsing unto itself in a controllable and directionally preselected manner by venting static air within said internal through openings in said gel article, said gel of said article having rigidity of from about 20 gram Bloom to about 1,800 gram Bloom suitable for cushioning, cushioning composites, cushioning gel liners, cushioning composite gel liners, and other uses of selected shape gels, gel composites, and articles.

Abstract: Device designed for regenerating the human dermis presented in the form of a multilayer complex combining an absorbable polymeric internal matrix able to induce the regeneration of the dermis by contact with muscle or subcutaneous tissue, an open-work textile mesh and a transparent external support wherein the open-work textile mesh is contained in the body of the transparent support.

Abstract: A filtered fluid pump spray dispenser and applicator assembly includes a container having a pump spray mechanism connected to a fluid feed tube immersed in a fluid to be dispensed. The open end of the fluid feed tube is covered by a porous and permeable filter, which filters particulate matter from the fluid during spray mode fluid dispensing. The pump mechanism and fluid feed tube may be removed, and fluid contained in the filter applied directly to a surface in direct application mode fluid dispensing.

Abstract: The present invention provides a method of treating a leg ulcer comprising contacting the leg ulcer with a collagen biofabric. The leg ulcer may be a venous, arterial, diabetic or decubitus (pressure) ulcer. The invention further provides kits comprising one or more pieces of collagen biofabric for the treatment of a leg ulcer.

Abstract: The subject invention pertains to a method, apparatus, and composition of matter for producing near-infrared (near-IR) radiation. The subject invention can incorporate a polymer and a metal-containing compound, wherein the metal-containing compound can incorporate a metal-ligand complex, wherein when the metal-ligand complex becomes excited, energy is transferred from the ligand to the metal, wherein, the energy transferred to the metal by sensitization is emitted as near-infrared radiation. In a specific embodiment, the subject invention relates to a composition of matter having a luminescent polymer and a metal containing compound where the metal containing compound incorporates a metal-ligand complex such that the absorption spectrum of the metal-ligand complex at least partially overlaps with the emission spectrum of the luminescent polymer.

Abstract: The present invention provides a device and kit and method of use thereof for wound treatment of a subject. The device may include an electrically operated patch or other means of delivery of electrical current and a connected moist surface. Optionally, the device may include a composition comprising an active substance useful in wound treatment. Preferably, the means of delivery of electrical current includes a power source and a plurality of electrodes disposed in a suitable conformation on a base substrate layer, which readily facilitates electrical contact with the body area of the subject. Preferably, the kit may include a means of delivery of electrical current and a moist surface provided as separate components. The present invention further provides a thin and flexible device for galvanic treatment to treat wounds with electrical stimulation. Preferably, the device is made using a printing technique.

Abstract: A method and system for producing an improved dressing product, useful for covering/protecting a moist wound is disclosed. The dressing product comprising fibers of a spinnable polymer forming a twisted ribbon. By virtue of this twisting, the fibers, in particular at the periphery of the ribbon, are connected to one another so as to afford better mechanical cohesion and a smoother outer appearance, without affecting the action of absorption, dilation and gel formation for extracting the biological fluid, nor the action of retention of proteins and other cellular and bacterial waste matter which would impede the phenomenon of cicatrization. The ribbon twisting equipment comprises a conical bowl (1) for driving fibers in rotation with a twisting die (3) in its narrowed downstream part (2), and a gear mechanism (4) for driving in rotation.

Abstract: A wound care bandage for treating a wound is provided. The bandage includes an SIS layer to be placed on the wound surface and a cover to placed over the wound. Illustratively, the bandage further includes a structure to provide a vacuum space. A method for promoting wound healing is further provided. The method includes applying the above-mentioned wound care bandage to the wound and creating a vacuum in the vacuum space to draw blood controllably from the wound into the SIS layer.

Abstract: A wound dressing including an absorbent core defining opposed proximal and distal surfaces, the distal surface of the absorbent core defining a central portion, a border portion and an intermediate portion interposed between the central and border portions. The backing layer defines at least one compliant element disassociated from the distal surface of the absorbent core and including at least one ridge extending outwardly relative to the distal surface of the absorbent core.

Abstract: A method of treating a wound using a customized dressing. In the method, at least one wound characteristic is evaluated. A treatment need as a function of the at least one wound characteristic is determined. A dressing having a dressing characteristic responsive to the treatment need is fabricated and applied to the wound. A dressing for use therewith and an apparatus and system for fabricating the dressing are provided.

Abstract: A body adhesive tape comprising a stretch base material and an adhesive layer with grooves.

Abstract: A wound insert or wound packing for preventing wound closure is provided. Such packing may be used alone or in regular bandages or in vacuum bandages or in irrigation bandages. Some illustrative wound inserts are configured for placement within an undermined portion or a tunneled portion of a wound.

Abstract: The present disclosure relates to nitric oxide sensors and systems. In some embodiments one or more devices are provided that include one or more nitric oxide sensors; one or more transmitters; and one or more controllers configured to transmit using the one or more transmitters one or more signals that are associated with controlling one or more nitric oxide generators.

Abstract: An adhesive device used as a wound dressing, ingredient delivery device or IV hold-down in which inadvertent edge release of these devices along the periphery of the polymeric film layer is minimized when the handling layer, which is adhered to the polymeric film layer, is removed after application of the polymeric film layer to the patient.

Abstract: The present invention relates to a self-adhesive dressing comprising a layer (1) of spunlace nonwoven material and attached thereto a layer (2) of adhesive. In accordance with the invention, the dressing is stretchable in a first direction (MD) corresponding to the machine direction of the nonwoven material and in a second direction (CD) perpendicular to the first direction, in conjunction with which the resistance to stretching is less than 10 N/25 mm in both the first (MD) and the second (CD) directions in the case of stretching of less than or equal to 5%.

Abstract: A dressing product comprises a dressing sheet (102), such as a thin film, one first surface of which is coated with an adhesive (106), such as a pressure sensitive hydrocolloid adhesive, which is applicable to an anatomical surface of a living being, such as a skin portion of a human. A carrier system, which provides a support for the dressing sheet, defines a gripping section for handling of the carrier system by human fingers. The carrier system may include one or more foil members (216;218;220;222) and supporting sheets (212) for facilitating application and for providing a non-touch application system, i.e. a system which may be handled by an operator without the operator touching the dressing sheet (102) or at least the adhesive surface (106) thereof. A protective sheet having an opening for application of a pharmaceutical product to the adhesive prior to application of the dressing sheet is disclosed.

Abstract: This invention relates to an elastic bandage for supporting a body extremity such as a leg. Such bandages are used to overcome problems with fluid retention and swelling in the legs, occurring as a consequence of varicose veins, vascular incompetence, pregnancy, etc. It is a task of this invention to supply an active support for a body extremity such as a leg, which can be used by a person underneath the clothes and will not reduce the mobility of the patient. This task is solved in that an elastic bandage comprises an elastic layer for surrounding a body extremity to exert compressive force on the extremity, the bandage being, at least partly, formed by elastomeric actuation elements, whereby electrical control of the compressive force is possible, and where the control is due to a signal from some sensing system.

Abstract: A protective foot pad includes a sheet of protective material having a main body portion in the shape of the ball of a human foot and a locating tab extending from the main body portion for location between the first and second toes of the foot, an adhesive on one surface of the sheet for adhering the sheet to the foot, and a removable release liner covering the adhesive until the pad is to be adhered to the foot. The pad is especially suited for protecting the bare foot of a dancer, who will use the pad by removing the release liner to expose the adhesive, placing the exposed adhesive on the bottom of his or her foot to cover at least a portion of the ball of the foot, with the tab extending between the first and second toes, and bending the locating tab over the skin between the first and second toes. The main body portion can include one or more lateral extensions that adhere to the side of the foot.

Abstract: The present disclosure relates to substrates associated with nitric oxide.

Abstract: The disclosed two-component device includes a first component comprising a first adhesive-backed anchoring member and one or more first connecting members, produced separately from the first adhesive-backed anchoring member. The first connecting member is attached to the first adhesive-backed anchoring member, extending from One edge thereof in a first direction. Also disclosed is a second component comprising a second adhesive-backed anchoring member and one or more second connecting members, produced separately from the second adhesive-backed anchoring member. The second component is attached to the second adhesive-backed anchoring member, extending from one edge thereof in a second direction generally opposite to the first direction. Adhesive for attaching the one or more first connecting members to the second anchoring member and adhesive for attaching the one or more second connecting members to the first anchoring member is provided. Methods of use are also disclosed.

Abstract: The invention relates to a self-adhering bandage that is secured in place without an adhesive/skin contact point. The bandage may include a substance storage area that houses a substance that is transferred to the dressing component when pressure is applied to the substance storage area.

Abstract: A method for applying pressure to skin with a dressing. The method including adhering at least a portion of the dressing to the skin and changing the shape of the dressing after application of the dressing to the skin wherein the changed shape applies pressure to the skin. The changing can include releasing a member from the dressing to allow the dressing to change the shape of the dressing; deforming at least a portion of the dressing to change the shape of the dressing or allowing the dressing to heat to above a transition temperature at which the dressing changes shape.

Abstract: A chest seal for treating an open pneumothorax that is low profile and thus unobtrusive so that the chest seal can be effectively maintained in position to seal a chest wound while allowing the pleural cavity to vent.

Abstract: An apparatus for cleansing wounds, in which wound exudate is removed from a wound bed and selectively cleansed and returned to the wound. The cleansing means removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The associated wound dressing and cleansing means are conformable to the wound, and may have irrigant fluid circulated from a reservoir by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing.

Abstract: A chitosan biomaterial is frozen in aqueous solution to form a frozen chitosan structure from which water is removed by a prescribed freeze-drying process to form a sponge-like chitosan structure having a thickness and a density. The sponge-like chitosan structure is compressed by application of heat and pressure to reduce the thickness and increase the density of the sponge-like chitosan structure to form a densified chitosan structure. The densified chitosan structure is further preconditioned by heating the densified chitosan structure according to prescribed conditions to form a wound dressing. The wound dressing possesses an adhesion strength and resistance to dissolution in high blood flow bleeding situations.

Abstract: A medical device is provided that encloses a wound and promotes wound drainage by suction. The device includes an enclosure to be placed over a wound, adhesively connected to the skin around the wound by a flange. Gauze type packing cylinders can be placed in the wound, and suction is provided either by a bulb type pump, or by a pair of regulators. When regulators are used, one alternates the suction that it provides, and the other is continuous, such that the level of suction is periodically varied. The suction facilitates the transfer of liquid from the wound to the packing cylinders and from the packing out of the enclosure. A leak detector is optionally provided.

Abstract: To provide a patch containing fentanyl for mucous membrane of the oral cavity (oral transmucosal fentanyl), which rapidly increases the serum concentration of the drug, is easy in handling and is superior in safety. The patch can be prepared by laminating on one side of a drug layer which contains fentanyl or its salt as an active ingredient, methyl vinyl ether-maleic anhydride copolymer as an adhesive, and at least one substance selected from the group consisting of hydroxypropylcellulose, hydroxypropylmethylcellulose and hydroxyethylcellulose as a thickener, a support layer hardly soluble or insoluble in water, and a backing in this order.

Abstract: A self-adherent window dressing includes a fabric layer bounded by an edge. The fabric layer has an adhesive side, an opposite non-adhesive side, and an opening therein to allow for viewing therethrough. The opening is defined by a peripheral edge. A transparent film layer closes the opening and has first and second opposing sides. The film layer first side is non-adhesive and is mounted on the fabric layer adhesive side to close the opening in the fabric layer. The film layer second side has a skin adhering adhesive portion and an adhesive-free portion. The adhesive-free portion is disposed partially in the opening and extending beyond the peripheral edge of the opening. The film layer adhesive-free portion is adapted not to stick to a patient's skin, a connector, a catheter, or other medical device disposed between the film layer adhesive-free portion and skin.

Abstract: This invention pertains to a polymeric composition and an antimicrobial composition, each comprising a superabsorbent polymer (SAP), such as used in diapers and sanitary napkins, and peroxide. The superabsorbent material can be made by the process of treating a preformed SAP, such as a crosslinked polyacrylate salt, with a treatment solution comprising hydrogen peroxide dissolved in water, followed by drying. The resulting superabsorbent material has strong antimicrobial activity. Optionally, the treatment solution may also contain a metal salt, including those of zinc, zirconium, and magnesium.

Abstract: A vacuum assisted wound closure device having a means for identifying infectious agents within a wound site. The vacuum assisted wound closure device includes a screen for placement within a wound site, a sealing means for covering the wound site, and a vacuum source in fluid communication with the screen. A canister may be disposed between the screen and vacuum source, such that fluids or other exudates that may be drawn from the wound during application of negative pressure by the vacuum source are collected in the canister for later disposal. A sensing device, which may be a gas chromatograph, sensor array, or other similar device capable of optically sensing the presence of a bacterial agent or other form of infection being drawn from the wound site, is disposed within the screen or interposed between the screen and the vacuum source.

Abstract: An anti-snoring device that attaches to a specific area of the neck. The attachment means can be an adhesive, a clip or an implant. The device exerts a predetermined pulling force on this area of the neck, causing this area of the neck to expand outward from its normal position. This expansion opens a blockage in the throat of a sleeping person, thereby eliminating snoring and helping some people with obstructive sleep apnea.

Abstract: A wound dressing apparatus for use in subatmospheric pressure therapy includes an outer member dimensioned for positioning relative to a wound bed and defining an internal reservoir, a port associated with the outer member and in communication with the internal reservoir for applying subatmospheric pressure to the internal reservoir to facilitate treatment of the wound bed and removal of fluid therefrom, an inner member at least partially positionable within the wound bed and confined within the outer member, and an adhesive agent in contact with a peripheral section of the outer member to facilitate attachment of the peripheral section to the periwound tissue. The adhesive agent is preferably substantially devoid of contact with the inner member. In one embodiment, a layer of adhesive material is disposed on the peripheral section of the outer member.

Abstract: A cushioned medical securement device for cushioning and securing a patient medical device includes a laterally and longitudinally extending pad. The pad has an adhesive coated first side surface for adhering to the patient medical device and an opposing adhesive coated second side surface for adhering to a patient's skin. A first release liner is removably mounted on the first side surface. The first release liner has a first liner peel release value. A second release liner is removably mounted on the second side surface. The second release liner has a second liner peel release value that is greater than the first liner peel release value.

Abstract: Dressings, systems, and methods to facilitate the application of reduced pressure to an extremity, such as heel, on a patient are provided. In one instance, a dressing for treating an extremity on a patient includes a drape envelope, a transport manifold, and a pouch. The drape envelope has an outer drape member, inner drape member, and an interior portion between the outer drape member and the inner drape member. The inner drape member has fenestrations on at least an application portion. The transport manifold is disposed within the interior portion of the drape envelope. The pouch is for receiving the extremity and includes the drape envelope and a pouch-forming attachment. The dressing allows reduced pressure to be initially supplied at a remote location from the wound and avoid leaks. Other systems, methods, and apparatuses are disclosed.

Abstract: A tissue treatment device suitable for use on an extremity, such as a hand or foot, includes a cover formed as a bag, sac, or pouch, and a support member disposable within the cover to support a portion of the cover off of, and out of contact with, tissue to be treated. The cover has an open end with attachment means disposed thereon for attachment to a limb whose extremity is received in the cover.

Abstract: A wound treatment device comprising a water-impermeable envelope having at least one aperture. The envelope contains a therapeutic substance. The at least one aperture in the envelope is blocked by a material that breaks down in the presence of one or more active components of wound fluid thereby permitting the therapeutic substance to contact the wound fluid. Preferably, the aperture is blocked by a material that is a substrate for an enzyme present in would fluid, such as a protease.

Abstract: Hydrocolloid-containing pressure-sensitive adhesive compositions for medical use are disclosed which contain networks of fibrillated polymeric fibers that have surface areas of at least 4 square meters per gram and which have superior properties of low cold flow and high cohesive strength.

Abstract: A biocompatible wound dressing comprised of a pad for insertion substantially into a wound site and a wound drape for sealing enclosure of the foam pad at the wound site. The pad, comprised of a foam or other like material having relatively few open cells in contact with the areas upon which cell growth is to be encouraged so as to avoid unwanted adhesions, but having sufficiently numerous open cells so that drainage and negative pressure therapy may continue unimpaired, is placed in fluid communication with a vacuum source for promotion of fluid drainage, as known in the art. The pad is further comprised of an ultra-low density fused-fibrous ceramic, or a bioabsorbable branched polymer, or cell growth enhancing matrix or scaffolding.

Abstract: A wound closure apparatus having a porous pad adapted to be fluidly connected to a vacuum pump. The pad is placed over or within a tissue site, and the vacuum pump may be activated to draw air and exudates from the tissue site. The pad contains multiple pore sizes to prevent granulation tissue from migrating into the pad as reduced pressure treatment is applied. The pad has an outer surface adjacent the wound with pore sizes of a diameter of approximately 100 microns or less to prevent tissue from growing into the pad and is treated for biocompatibility.