Abstract: A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydrocolloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer.

Abstract: In one embodiment, a medical device for containing or applying a pressure or a combination thereof to an area of skin or wound of a user is provided. The medical device includes a bandage body, a pad component disposed thereon, body, an adhesive component, and an opening adjacent to the first end of the bandage body, wherein the opening is configured to receive at least a portion of the bandage body such that when the second end of the bandage body is received within the opening, the adhesive portion of bandage body can be attached to a portion of the bandage body such that the adhesive does not contact the user.

Abstract: A wound closure system having first, second and third adhesive pads with a pair of strap members fixedly secured to the first and third adhesive pads. The pair of strap members are slidably received within the second adhesive pad. When the third adhesive pad is displaced, the first and second adhesive pads are displaced toward each other to close the wound.

Abstract: A unique multi-functional emergency bandage is introduced, wherein bleeding is stopped by: (1) optimizing mechanical properties and preventing ischemia and/or necrosis while applying enough pressure to help stop bleeding, and (2) incorporating inorganic anti-bleeding nano-structures (embedded within a gauze and/or microbial cellulose) with almost infinite life-time. Additionally, pathogen passage through the bandage is prohibited (via an intermediate filter layer). Together with the overall anti-microbial character of the bandage, the unique multi-functional bandage offers all these vital features within a single design. The unique bandage can be applied by using a single hand and bandaging direction can be changed using a unique binding apparatus.

Abstract: The present invention relates to an adherent interface dressing intended for application directly to a wound.

Abstract: Devices and methods relate to inducing or promoting hemostasis. The hemostasis device may include a support layer having a first surface and an opposing second surface. The device may include a layer, the layer disposed on the first surface. The layer may include a target surface configured to contact a target site. The layer may include a monolayer of about 100% graphene or may include laser-reduced graphene oxide. The device may include a sensor configured to measure a level of hemostasis of the target site. The methods relate to a method of manufacturing a hemostatic device including a monolayer of graphene or a layer of laser-reduced graphene oxide.

Abstract: The present invention is drawn to adhesive peel-forming formulations for dermal delivery of a drug. The formulation can include a drug, a solvent vehicle, and a peel-forming agent. The solvent vehicle can include a volatile solvent system having one or more volatile solvent, and a non-volatile solvent system having one or more non-volatile solvent, wherein the non-volatile solvent system has a solubility for the drug that is within a window of operable solubility for the drug such that the drug can be delivered at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified peelable layer after at least a portion of the volatile solvent system is evaporated.

Abstract: A wound dressing and method of forming the same. In one embodiment, the wound dressing includes a two-sided adhesive band conformable to a surface of a person. The wound dressing also includes a removable bandage configured to attach to an upper surface of and seat over the two-sided adhesive band, thereby forming a substantially closed structure for application over a wound on the surface of the person.

Abstract: There is provided a dressing for treating a wound. The dressing for healing a wound can be useful in maintaining a moisture environment at a wound site using a biocompatible polymer scaffold, and effectively promoting healing of a wound by various growth factors secreted by skin cells or stem cells attached to the biocompatible polymer scaffold as well.

Abstract: The Technology described herein applies to medical dressings designed to heal wounds in the area of advanced wound care, inclusive of Negative Pressure Wound Therapy (NPWT), and describes novel wound healing absorbent scaffolds and dressing based on natural and naturally-derived material and fibers, preferentially poly (lactic) acid fibers and alginate materials.

Abstract: The invention relates to a transdermal therapeutic system made of the following layers: a carrier layer (T), an active ingredient layer (R), a membrane layer (M) and optionally an adhesive layer (K), wherein the carrier layer (T) is impenetrable to the active substance and to water, the active substance layer (R) comprises as an active substance component the salt of an alkali reactive active substance, such as a CNS-active amine in combination with at least one alkali reactive further component, and a polymer component (P1), wherein the active substance is released from the active substance layer (R) only by the moisture entering from the exterior through the membrane layer (M), and the membrane layer (M) is made of a polymer component (P2), allowing a uniform delivery of basic active substances to the skin.

Abstract: A vacuum bandage is provided for use with a wound having a wound surface. The bandage is connectable to a vacuum source and includes a wound dressing member having a wound contacting surface, a top surface, and a port configured for communication with the vacuum source. The wound dressing member further includes holes in the wound contacting surface configured for communication with the wound surface of the wound and a passageway between the port and each hole. The vacuum bandage further includes a pack adjacent to the top surface of the member. The pack may include an aperture positioned about the port.

Abstract: A dressing for application to a wound or burn is provided. The dressing includes a substrate and an amount of therapeutic healing compound applied to the substrate. The therapeutic healing compound includes a sugarcane plant extract, a gelling agent including at least one of xanthan gum and hydroxyethyl cellulose, and collagen.

Abstract: Wound dressings, methods for their production and components for use therein. A knitted structure comprising a blend of gelling fibres and non-gelling fibres wherein the yarn comprises at least 50% w/w gelling fibres, a three-dimensional textile material comprising gelling fibres, and a yarn comprising a blend of gelling and non-gelling fibres which may be used in their production, the knitted structure and three-dimensional textile material beings suitable for use as wound dressings or as components of composite wound dressings. The wound dressings may be adapted for use in negative pressure wound therapy (NPWT). It has been found that the incorporation of gel-forming fibres provides a material which has a high absorbency, enabling good transfer of exudates away from a wound, which retains structural integrity, and which is non-adherent and easily removed from the wound.

Abstract: A device for the protection of skin lesions of various kinds, in particular lesions following biopsy interventions, including: a first sheet having a central opening; a spacing element on the first sheet, made of a non-rigid material soaked with substances having bacteriostatic, bactericidal, germicidal or fungicidal activity, and having a central opening of smaller size than the central opening in the first sheet, and the center of which is essentially coincident with the center of the opening in the first sheet, so that part of the spacing element comes into contact with the skin in an area surrounding the lesion; and a second sheet, made with a material having micro-porosity preferably lower than 0.5 m, placed over the spacing element so as to close the top of the central opening in said spacing element and to form, when the device is in contact with the skin, a closed chamber.

Abstract: A dressing support system and method of use for bandaging patient wounds in an efficient, cost effective, and repeatable manner by practitioners, non-professionals, and home caregivers according to unique specification dictated by wound care specialist without the need for extensive training or wasted materials of trial and error techniques.

Abstract: Medical devices, wound dressings, and methods of dressing wounds are described. Devices and methods using silicone and pharmaceutically active agents are described. Devices including covers and bases are described.

Abstract: Wound dressing articles comprising a nonwoven web comprising a plurality of fibers having grafted pendant hydrophilic groups, methods that use high energy irradiation for making a plurality of fibers having grafted pendant hydrophilic groups, useful for making wound dressing articles.

Abstract: A protective device configured in accordance with a particular embodiment includes a cover including a first region that extends over a vulnerable site on a patient and a second region that extends over an area on the patient peripheral to the vulnerable site. The first region of the cover is at least generally impermeable to liquid water. The device further includes an adhesive film and a liquid-absorbing element. The adhesive film is configured to form an adhesive bond between the second region of the cover and the patient. The bond has an inner edge portion positioned toward the vulnerable site and an outer edge portion positioned away from the vulnerable site. The liquid-absorbing element is configured to absorb liquid contamination at the outer edge portion of the bond and/or liquid contamination approaching the outer edge portion of the bond when the cover is operably positioned on the patient.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: Cranial caps designed to serve as an infection barrier and that can easily be placed on and removed from a patient's head are provided herein. Preferred cranial caps include an aperture that can be opened and closed that allows medical personal to easily inspect and/or treat the wound while the patient is wearing the cranial cap.

Abstract: In one aspect, a wound treatment system includes an inner layer comprising a foam material impregnated with a zinc oxide containing composition with or without calamine and/or ichthammol and in the presence or absence of antimicrobial agent (inorganic and/or organic). An optional outer layer comprises a short/long stretch compression bandage. In another aspect, a method of manufacturing the foam article impregnated with the zinc oxide containing composition is disclosed. In yet another aspect, a method of applying the wound treatment system to a patient's leg is disclosed. In still another aspect, a kit is provided including a foam layer impregnated with a zinc oxide containing composition; optionally, an elastic bandage component (e.g., long or short stretch elastic bandage); and, optionally, an outer stocking or sleeve, wherein the bandage system components are packaged together.

Abstract: A wound dressing comprising an open-cell foam substrate infused with an ion-containing composition in a water-dispersible carrier is provided. The composition includes citric acid or a salt thereof; salts of potassium, rubidium, and zinc ions; and a carrier comprising two or more polyol components, at least one polyol component being solid at 23 degrees C. A method of treating a wound with said wound dressing is also provided.

Abstract: An antimicrobial medical dressing provides a combination of antimicrobial agents in various concentrations that protect against microorganisms, absorb exudates, and promote healing. The antimicrobial agents may include compositions of ethanol, hydrogen peroxide, and/or ethylenediaminetetraacetic acid.

Abstract: A dental dressing to promote healing and relieve pain and swelling associated with exposed dental alveoli. The dressing includes a three-dimensional dressing matrix to absorb leaked fluid associated with one or more exposed alveoli, and a therapeutic member to provide substantially localized cold therapy to one or more exposed alveoli, the therapeutic member embedded substantially within the dressing matrix and shaped to substantially engage one or more exposed alveoli while fitting substantially between contiguous teeth. At least part of the dressing matrix substantially conforms to one or more exposed alveoli, thereby engaging the therapeutic member with one or more exposed alveoli.

Abstract: A medical device for example a wound dressing having antibacterial and optionally, antifungal properties, are provided together with methods for making the device. An exemplary dressing includes a layer of silver-containing fabric, (optionally) a layer of absorbent material, and (optionally) a layer of flexible air-permeable and/or water-impermeable material. The dressing can be used for prophylactic and therapeutic care and treatment of skin infections and surface wounds (including surgical incisions), as a packing material, and as a swab for surface cleaning.

Abstract: Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween.

Abstract: A device for preventing development of infections includes a surgical drape in which a window, through which an incision may be made, is formed. The window defines borders having an inner face; a first layer of a material, covering the inner face of the borders, the first layer being configured to absorb incision secretions; and a second layer, covering the inner face of the borders, the second layer being impregnated with an antiseptic haemostatic ingredient, the second layer partially covering the first layer, the first layer being wider than the second layer. The second layer is arranged to come into contact with incision margins and cover a top part and a bottom part of an incision during installation of a spacer.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: Wound dressings and wound inserts comprising substantially dry reactive agents, methods of forming wound inserts comprising dry reactive agents, and wound-treatment methods.

Abstract: In one aspect, a wound treatment system includes an inner layer comprising a foam material impregnated with a zinc oxide containing composition with or without calamine and/or ichthammol and in the presence or absence of antimicrobial agent (inorganic and/or organic). An optional outer layer comprises a short/long stretch compression bandage. In another aspect, a method of manufacturing the foam article impregnated with the zinc oxide containing composition is disclosed. In yet another aspect, a method of applying the wound treatment system to a patient's leg is disclosed. In still another aspect, a kit is provided including a foam layer impregnated with a zinc oxide containing composition; optionally, an elastic bandage component (e.g., long or short stretch elastic bandage); and, optionally, an outer stocking or sleeve, wherein the bandage system components are packaged together.

Abstract: A composition and wound dressing for treating a skin wound is disclosed. The composition and dressing comprise a pharmaceutically acceptable carrier; an effective amount of an active ingredient of inorganic solids comprising a potassium salt, a zinc salt, a calcium salt, and a rubidium salt; and an antimicrobial biguanide compound comprising an amount effective to reduce the number of viable microorganisms at a wound site. Methods of use include contacting a wound site with the composition and/or dressing.

Abstract: A method of alleviating pain associated with tissue damage includes applying salmon thrombin at a tissue damage site, as a single substance in liquid form, or as a powder, a foam, and/or a gel that includes salmon thrombin. A pain relief substance includes a salmon thrombin preparation.

Abstract: Devices and methods are disclosed for achieving hemostasis in traumatized patients. Such haemostatic packing devices and methods are especially useful in the emergency, trauma surgery or military setting. The patient may have received trauma to abdominal viscera, the thoracic cavity or the periphery. The devices utilize fluid impermeable outer surfaces and distributed pressure to achieve tamponade and hemostasis, primarily by exertion of pressure. The devices come in a variety of configurations including sheet, rolled sheet, folded sheet and polygonal solids including extruded shapes. The devices are capable of serving as carriers for thrombogenic or anti-pathogenic agents. The devices are flexible, bendable, and conformable in their wet or dry state so that they exert distributed pressure on the wound. The hemostatic packing devices may be placed and removed by open surgery or laparoscopic access without generating excessive re-bleeding, and may further comprise antimicrobial or thrombogenic regions.

Abstract: A heat and anesthetic pack comprising an instant heat pack, where the instant heat pack includes a front side and a back side; an occlusive dressing attached to a central portion of the front side of the instant heat pack; a central blister pack attached to a center portion of the occlusive dressing, where the central blister pack includes a numbing cream; and a peel-away covering positioned above the occlusive dressing and the central blister pack, where the peel-away covering remains in place until a user is ready to use. During use the user places the heat and anesthetic pack on the user's skin with the central blister pack and the occlusive dressing exposed to the skin. The numbing cream numbs the skin while the heat pack promotes drainage.

Abstract: A wound closure system having first, second and third adhesive pads with a pair of strap members fixedly secured to the first and third adhesive pads. The pair of strap members are slidably received within the second adhesive pad. When the third adhesive pad is displaced, the first and second adhesive pads are displaced toward each other to close the wound.

Abstract: The present invention relates to wound treatment material comprising at least two perforated biomatrix layers interconnected by connecting means, as well as to methods for preparing such wound treatment materials and their use, in particular in the treatment of exuding wounds, and in the vacuum-assisted wound treatment therapy.

Abstract: The present invention pertains to nonwoven webs, and multi-component fibers comprising polydiorganosiloxane polyamide as well as method of making microfibers and multi-component fibers comprising a polydiorganosiloxane polyamide copolymer.

Abstract: A biocompatible wound dressing comprised of a pad for insertion substantially into a wound site and wound drape for sealing enclosure of the foam pad at the wound site. The pad, comprised of a foam or other like material having relatively few open cells in contact with the areas upon which cell growth is to be encouraged so as to avoid unwanted adhesions, but having sufficiently numerous open cells so that drainage and negative pressure therapy may continue unimpaired, is placed in fluid communication with a vacuum source for promotion of fluid drainage, as known in the art. The pad is further comprised of an ultra-low density fused-fibrous ceramic, or a bioabsorbable branched polymer, or cell growth enhancing matrix or scaffolding.

Abstract: The medical protective cover includes a semi-ovoid shell configured to cover a wound or intravenous site. The shell is attached to a patient's limb or extremity by a pair of adhesive tabs extending from longitudinal ends of the shell and a plurality of adjustable straps extending laterally from the shell. A plurality of ventilation holes longitudinally extend along lateral edges of the shell to allow passage of air for keeping the covered area dry. Each longitudinal end of the shell includes a pair of tubing ports to facilitate mounting and passage of IV infusion tubing to an IV catheter or cannula. The top of the shell also includes a selectively opened slot that permits passage of a needle for the administration or withdrawal of fluids through an access port of the catheter.

Abstract: A wound dressing having anti-microbial activity comprises a first fiber capable of bonding with silver (1) cations. The wound dressing comprises a blend of the first fiber to which silver (1) cations are bonded and a second fiber which is substantially free from silver. The wound dressing comprises from 0.01 to 5.0 percent by weight of silver (1) cations, based on the weight of fiber.

Abstract: A wound dressing applicator (10) for applying hydrocolloid dressings, compositions for tissue regeneration and the like to a patient's skin. Known wound dressing applicators do not effectively protect against contamination of the wound dressing and/or can be fiddly and difficult to operate and be rendered unusable by unwanted premature separation of the various layers of material adhered to one another. The present applicator comprises a rigid body (20) having a rigid body enclosure (30) for receiving a wound dressing, and an ejector (40) for ejecting the wound dressing from the rigid body enclosure and onto a patient's wound. This enables effective and aseptic handling of a wound dressing and application of the wound dressing onto a patient's wound.

Abstract: A hyperbaric dressing has a fluid impermeable sheet and a fluid permeable layer with a sheet of porous material positioned between these two layers with passageways to permit fluid to flow out of the dressing.

Abstract: A therapeutic device for promoting the healing of a wound in a mammal is disclosed. An exemplary device comprises a permeable structure having a plurality of depressions formed in a surface thereof. In use, the surface having the depressions is disposed adjacent a surface of the wound. A method of manufacturing a therapeutic device for promoting the healing of a wound in a mammal comprising the steps of providing a permeable substrate, and forming a plurality of depressions into a surface of the permeable substrate to provide the therapeutic device. A method of treating a wound comprises: providing a permeable structure comprising a plurality of randomly disposed fibers and having i) a plurality of wound surface contact elements disposed between end portions of the structure, and ii) a plurality of voids defined by the contact elements; and applying the permeable structure to at least one surface of the wound.

Abstract: A dressing for covering a wound. The dressing including: a first component having a first shape with a first dimension; a second component releasably attached to a first surface of the first component to maintain the first component in a second shape different from the first shape, the second shape having a second dimension longer than the first dimension; and an adhesive disposed on a surface of the first component different from the first surface for attaching the first component to the wound such that the second component can be released from the first component to allow the first component to take the first shape to apply a pressure to portions of the skin surrounding the wound to close the wound. Wherein the first and second dimensions are a length in more than one direction.

Abstract: An electrode system include a flowable and cohesive surface contact element comprising a hydrophilic polymer swollen with an electrolyte fluid, the contact element having a Q? ratio of at least 5 as defined by the equation Q ? = W W W G wherein WG is the dry weight of the hydrophilic polymer and WW is weight of water in the sample after absorption of the electrolyte fluid comprising water and an electrolyte salt. The surface contact element can consist essentially of the hydrophilic polymer swollen by the electrolyte fluid. Another electrode system includes a contact element including a crosslinked hydrophilic polymer matrix. The contact element has a Q? ratio of at least 5 as defined by the equation Q ? = W W W G . The contact elements can also have a Q? ratio of at least 6, at least 7, at least 10 or even at least 11.

Abstract: A wound dressing includes one or more layers containing an antimicrobial agent and optionally at least one of: a chelating agent, a second antimicrobial agent, a zinc-containing agent, a cell-signaling agent, and an additional active ingredient or agent.

Abstract: A hydrogel formulation is provided for use with a film. The hydrogel formulation includes a medical-grade hydrogel and an antimicrobial substance. This hydrogel formulation may be coated onto one or more surfaces of a medical-grade transparent film suitable for a wound dressing. The antimicrobial material may be a silane quaternary ammonium salt. The silane quaternary ammonium salt may comprise 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. The 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride may constitute about 72% by weight of the silane quaternary ammonium salt. The medical-grade hydrogel may comprise a colloidal gel in which the particles are dispersed in water. Further, the hydrogel formulation may include about 0.01% to about 60% by weight of the antimicrobial substance. The transparent film may further include a release liner applied over the coated side(s) of the transparent film. The transparent film may comprise polyurethane.

Abstract: A medicated patch is provided which is covered with a liner that enables one to remove the liner unconsciously and readily without losing the initial stickiness of the medicated patch. The external medicated patch includes a backing, an aqueous adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that is larger in size than the surface of the drug-containing matrix to which the liner is attached. The liner larger in size than the surface of the drug-containing matrix to which the liner is attached includes an unattached area that extends from the surface of the drug-containing matrix, or an unattached slack portion that projects upward from the surface of the drug-containing matrix at a position on the surface of the drug-containing matrix.

Abstract: An improved wound care system is set forth. The system includes a wound care device having a first end and a second end. A fastener, adapted to extend to a desired length to selectively attach the device at an anchor, wherein the anchor is provided on a second end of the device is also provided. The fastener is sufficiently sized and formed of a suitable material to prevent the device from moving when secured to the anchor. In an embodiment, medicine is provided in a desired treatment area of the device. The medicine can be inserted via a medicinal delivery device by inserting the medicinal delivery device up to a stop on the medicinal delivery device into the wound care device.