Having Means For Desensitizing Skin Patents (Class 604/112)
  • Patent number: 11547602
    Abstract: The present disclosure provides a device and a method for cooling living tissues for a medical purpose and other purposes. The cooling device comprises: a container configured to accommodate a cooling medium and thermally coupled with the cooling medium by directly contacting the cooling medium; a cooling generator configured to be thermally coupled with the container by a direct contact and thereby to provide cooling energy to the cooling medium; and a heat sink dissipating heat from the cooling generator, the heat sing being configured to be spaced apart from the cooling generator and to be thermally coupled with the cooling generator without a direct contact with the cooling generator.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: January 10, 2023
    Assignee: Recensmedical, Inc.
    Inventor: Gun-Ho Kim
  • Patent number: 11511114
    Abstract: A device and means to decrease the pain associated with cancer biopsies procedures The device uses anesthetic injections and electrical currents of both positive or negative polarity, or alternating current. The device can be incorporated into existing biopsiy devices. Application on breast cancer biopsies and other types of biopsies.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: November 29, 2022
    Inventors: Heather Marisa Richardson, Sergio Lara Pereira Monteiro
  • Patent number: 11399771
    Abstract: Various aspect of the present disclosure are directed toward apparatuses, systems, and methods that may include an introducer for facilitating placement of an implantable monitor. The introducer may include an indicator configured to indicate at least one of width, depth, and position for an arrangement of the implantable monitor relative to a patient.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: August 2, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Kathryn Sick, Keith R. Maile, Britta C. Veldman, Arthur J. Foster
  • Patent number: 10981003
    Abstract: An interferential current therapy kit for treatment of a patient following an orthopedic shoulder surgery includes, within a container for facilitating the distribution and transport of the kit, a first plurality of electrodes, a second plurality of electrodes and an interferential current therapy control unit. The interferential current therapy control unit is configured to supply interferential current electrical impulses, via the electrodes, so as to give rise to at least one first beat impulse acting on the suprascapular nerve of the patient and so as to give rise to the at least one second beat impulse acting on at least one of an axillary nerve and a supraclavicular nerve of the patient.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: April 20, 2021
    Assignee: Feinstein Patents, LLC
    Inventor: Peter A. Feinstein
  • Patent number: 10682512
    Abstract: An interferential current therapy kit for treatment of a patient following an orthopedic surgery, includes, within a container for facilitating the distribution and transport of the kit, one or multiple control units including a stimulation power supply and a plurality of electrodes configured to be in electrical communication with the stimulation power supply. The plurality of electrodes are configured to be disposed on an epidermis of the patient and arranged to supply transcutaneous electrical impulses to a therapeutic target area when supplied power by the stimulation power supply employing an interferential current therapy technique. The kit also includes an electrode placement aid adapted to assist the health care provider and team, and the patient with placement of the plurality of electrodes with respect to the site of the previous orthopedic surgery, thereby increasing a likelihood of efficacious and safe placement of the plurality of electrodes.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: June 16, 2020
    Assignee: Feinstein Patents, LLC
    Inventor: Peter A. Feinstein
  • Patent number: 10675417
    Abstract: A method and an apparatus for applying an anesthetic includes a receptacle having an upper end, a substantially hollow interior, a lower end having a tube or nozzle extending therefrom, and an attachment for attaching to the barrel of a syringe or vice versa. The receptacle receives a container or canister containing an endothermic gas or vapor(propellant) that rapidly absorbs heat when released to the atmosphere. A depressible actuating member or trigger propels the gas or vapor through an outlet nozzle that is oriented to project a stream of gas or vapor along a delivery axis that intersects a delivery axis of the needle, therefore, the gas or vapor can be successively delivered to an injection site with minimal repositioning of the housing.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: June 9, 2020
    Assignee: Leibovici, LLC
    Inventor: Jacob Leibovici
  • Patent number: 10166334
    Abstract: A medicine injector in which a barrel with a receiving cavity is adapted to slidably receive a syringe subassembly for axial movement therein. Upon removal of a safety and release of a syringe driver, the syringe driver moves forward and injects the syringe needle. Penetration controls are shown for controlling needle penetration depth. In one form the penetration control uses a sleeve and spring which are radially adjacent. A cushioning ring or other cushion may be used to reduce syringe breakage. A load distribution and guide ring may be used to distribute loading applied to the syringe and help guide the moving syringe.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: January 1, 2019
    Assignee: Washington Biotech Corporation
    Inventor: Ronald E. Wyrick
  • Publication number: 20150094661
    Abstract: A method and an apparatus for applying an anesthetic includes a receptacle having an upper end, a substantially hollow interior, a lower end having a tube or nozzle extending therefrom and an attachment for attaching to the barrel of a syringe or vice versa. The receptacle receives a container or canister containing an endothermic gas or vapor (propellant) that rapidly absorbs heat when released to the atmosphere. A depressible actuating member or trigger propels the gas or vapor through an outlet nozzle that is oriented to project a stream of gas or vapor along a delivery axis that intersects a delivery axis of the needle; therefore, the gas or vapor can be successively delivered to an injection site with minimal repositioning of the housing.
    Type: Application
    Filed: August 6, 2014
    Publication date: April 2, 2015
    Inventor: Jacob Leibovici
  • Publication number: 20150051545
    Abstract: Described is a medicament delivery device comprising a housing adapted to contain a syringe, a pain reduction device coupled to the housing, a coupling mechanism disposed in the housing and operably coupled to the pain reduction device, and a drive mechanism disposed in the housing and operably coupled to the coupling mechanism. Activation of the drive mechanism actuates the coupling mechanism to activate the pain reduction device.
    Type: Application
    Filed: March 20, 2013
    Publication date: February 19, 2015
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Charley Henderson, David Cross, Douglas Ivan Jennings, Ryan Anthony McGinley
  • Publication number: 20150045718
    Abstract: The present invention provides an infusion-patch comprising; a cannula; a base; at least one adhesive region in said base suitable for skin attachment; at least one skin-access area within said base; and at least one conduit in fluid connection with said at least one skin access area, wherein said at least one conduit in fluid connection with said at least one skin access area facilitates the transfer of an anesthetic substance within at least a first anesthetic-reservoir which may be removably attached and in fluid connection with said at least one contact area, promoting delivery of said anesthetic substance to said at least one skin-access areas, and wherein said anesthetic substance delivered to said skin-access areas may be at least partially replenished without removing said in fusion-patch.
    Type: Application
    Filed: March 11, 2013
    Publication date: February 12, 2015
    Applicant: SteadyMed Ltd.
    Inventors: Ian Shlomo, Jacob Rand, Jonathan Rigby
  • Publication number: 20150018801
    Abstract: Disclosed are applicators and methods injecting of a liquid anesthetic into a dental patient with no or minimal pain. In accordance with one embodiment the applicator is for intraligamentary injection and includes an elongated, thin member having an open distal free formed of a resilient and somewhat conformable material suitable for producing a substantially fluid-tight interface with the anatomic structures at the gingival sulcus to inject the anesthetic therein. In another embodiment the applicator includes a flexible skirt surrounding a sharpened cannula, with the cannula being movable with respect to the skirt. The skirt is arranged to receive the anesthetic to anesthetize the gum, whereupon the cannula can then pierce the gum to inject the anesthetic into the underlying anatomic structure.
    Type: Application
    Filed: July 10, 2013
    Publication date: January 15, 2015
    Inventor: Sargon LAZAROF
  • Publication number: 20150011971
    Abstract: The present invention presents an apparatus and methods to generate and deliver resonant vibrations to a hypodermic needle penetration site of a human body to reduce pain of needle prick by activating inhibitory neuronal mechanisms for pain perception. The apparatus comprises a longitudinal syringe carriage assembly which releasably holds and slidably moves a proximal portion of a syringe and a vibration assembly which generates and delivers vibrations to a vibration resonance enclosure located at a proximal end of the apparatus. The vibration assembly adjoins in parallel the syringe carriage assembly. A syringe with a needle moves forward in the syringe carriage assembly along a longitudinal axis and the needle penetrates a recipient's tissue which is in direct contact with and is vibrated by the proximal end of the apparatus.
    Type: Application
    Filed: July 6, 2013
    Publication date: January 8, 2015
    Inventor: Choon Kee Lee
  • Publication number: 20140378940
    Abstract: The present invention presents an apparatus and methods to generate and deliver circumferential mechanical vibrations to a hypodermic needle penetration site of a human body to reduce pain of needle prick by activating inhibitory neuronal mechanisms for pain perception. The apparatus comprises a detachably disposable proximal end that contacts with a tissue of a recipient and encircles a needle penetration site, a distal end that is configured as a conduit for electric power to the apparatus and a longitudinally tubular handle assembly that is connected to both proximal and distal ends and that houses a vibration assembly and a control and power assembly. The vibration assembly generates and delivers resonant vibrations to the recipient through the proximal end. A needle penetrates the recipient's tissue circumferentially surrounded by vibrations transmitted by the proximal end.
    Type: Application
    Filed: June 23, 2013
    Publication date: December 25, 2014
    Inventor: Choon Kee Lee
  • Publication number: 20140324021
    Abstract: An injection system including a wearable component (e.g., a patch) adapted to be worn by a user, and a medication delivery component (e.g., injection device) configured to cooperate with the wearable component to deliver medication to the user. The wearable component can provide a target area to the user for targeting the medication delivery component during use, and further serve to prepare the injection site to minimize the potential for injection site reactions. Both the wearable component and the medication delivery component can include electronics and/or other devices for detecting and/or communication information regarding usage of the injection system including dose amount, frequency, time, etc. The system can be configured to communicate such information to a third party, such as a health care professional.
    Type: Application
    Filed: November 7, 2012
    Publication date: October 30, 2014
    Applicant: Eli Lilly and Company
    Inventors: Michael Scott Ulrich, Andrew Vankirk Sweeney
  • Publication number: 20140276410
    Abstract: Systems, methods, and devices for providing subcutaneous hydration are disclosed. A system for providing subcutaneous hydration may include an infusion bag including a hydration fluid, a tubing removably connected to the infusion bag, a squeezable bulb at least partially encompassing the tubing for at least one of flushing and priming the tubing, and a deployment device including an integrated needle which is operative provide subcutaneous hydration through the needle. A deployment device for subcutaneous hydration includes a base may include a needle aperture, a spring-loaded barrel attached the base and including a needle, and a firing mechanism within the barrel for deploying the needle from the barrel and further operative to project the needle through the aperture only when a tent of skin has been raised within the aperture for injection. A method for providing subcutaneous hydration may include steps necessary to operate the systems and devices for subcutaneous hydration.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: University Hospitals Case Medical Center
    Inventors: Johnie Rose, Conor P. Delaney
  • Publication number: 20140221926
    Abstract: A device for invasive parenteral administration of pharmaceutical preparations and sampling of blood consists of: a cuff, a mounting frame for accommodating a sliding disc that consists of a movable front disc half and a movable rear disc half, said rear disc half being provided with a channel for accommodating a cassette cartridge for a cassette with needles; a vial of anaesthetic; and a scanning device. Upon compression of the disc halves, the scanning device locates a vein, a signal is given off, and the disc halves lock in the appropriate position. The needle is introduced into the blood stream by pressing on the lid of the cassette. The lid slides back and the tip of a syringe or of the cannula of a blood transfusion system or of the cannula of an evacuated blood sample container is introduced via a hermetic aperture situated beneath the lid.
    Type: Application
    Filed: July 24, 2012
    Publication date: August 7, 2014
    Inventor: Aleksandr Stanislavovich Psyanin
  • Publication number: 20140148790
    Abstract: Various embodiments disclosed herein relate to a device having a base and a stimulation module that can be attached to a patient's skin and actuated to mask the pain caused when sharp objects penetrate the skin. The stimulation module is designed to generate vibration energy, or alternatively, is designed to generate both vibration and electrical energy.
    Type: Application
    Filed: January 30, 2014
    Publication date: May 29, 2014
    Applicant: Innova Medical Design LLC
    Inventor: Rommel P. Vallero
  • Publication number: 20140142507
    Abstract: In an aspect, a medication delivering injector which includes a housing having opposing proximal and distal ends and an accessible internal cavity for inserting and removing a medicament container such as a syringe. The injector is designed to hold and manipulate a medication delivery device such as a large variety of standard and non-standard medical syringes with fixed or attached needles, assembled such that centrally located is a cylinder containing a liquid medicament and attached either permanently or removably to the distal end of the cylinder, is a hypodermic needle or cannula in fluidic communication with the cylinder. The needle can be from one-half inches to one-and-one-half inches in length in the illustrated embodiment and other sizes are possible by changes in scale of the injector. At the proximal end of the cylinder is an opening with an inserted seal or bung with an attached rod thus constituting a plunger.
    Type: Application
    Filed: May 3, 2013
    Publication date: May 22, 2014
    Inventor: Charles K. Armes
  • Patent number: 8715232
    Abstract: An apparatus for insertion of a subcutaneously insertable element within a body of a patient is described: The apparatus is used for delivery of a therapeutic fluid into a body of a patient and/or sensing of a bodily analyte The apparatus allows alleviating of pain associated with the penetrating of the skin of the patient during needle insertion.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: May 6, 2014
    Assignee: Roche Diagnostics Operations Inc.
    Inventors: Ofer Yodfat, Illai Gescheit
  • Publication number: 20140074025
    Abstract: The device allows the pain associated with the insertion of a needle of a syringe into the skin to be reduced. To do this, this device comprises a sleeve, which has a first rear portion to at least partially receive the syringe with the needle and a second front portion fitted with an end part, through which an opening passes for passage of the needle. A front face of the end part is intended to be applied with pressure against the skin of a person before insertion of the needle into the skin. This front face of the end part is arranged to receive an active substance for desensitizing the skin. The active substance can be applied to the skin at the instant the terminal part presses on the penetration site to desensitize the skin.
    Type: Application
    Filed: September 10, 2013
    Publication date: March 13, 2014
    Inventor: Karim-Frederic MARTI
  • Publication number: 20140074062
    Abstract: Drug pump devices with syringe or pen-injection configurations may utilize pre-filled drug vials or cartridges; the prefilled vials may be equipped with mechanisms for stirring their contents and/or changing a chemical environment therein to improve therapies. To facilitate combination therapies, multiple drug pump devices may be assembled into a larger system. Lancet insertion devices for use in conjunction with the drug pump devices may feature improved safety characteristics and/or mechanisms for minimizing pain and discomfort.
    Type: Application
    Filed: August 6, 2013
    Publication date: March 13, 2014
    Inventors: Sean Caffey, Alice Lai, Po-Ying Li
  • Publication number: 20140031747
    Abstract: A needle housing (115) having a distal end which is removably connectable to a source of injectable fluid (110) and a proximal end (80) for contacting a patient, as well as to an injection apparatus comprising the needle housing. The needle housing comprises (a) a hollow needle through which the injectable fluid is deliverable to the patient, the needle having a proximal end for insertion into body tissue of the patient, and (b) a chamber (75) having an open proximal end, the chamber surrounding at least part of the needle and extending proximally beyond the proximal end of the needle to the open proximal end. The open proximal end of the chamber is deformable and is moveable relative to the needle from a position in which the chamber extends proximally beyond the proximal end of the needle to a position in which the proximal end of the needle extends proximally through the open proximal end of the chamber.
    Type: Application
    Filed: May 24, 2012
    Publication date: January 30, 2014
    Inventor: Massoud Hosseini Ardehali
  • Publication number: 20130338586
    Abstract: A injection device may be disclosed. The device may include an outer casing, a needle, and a plurality of projections surrounding the needle. The needle may be adjustable between a first position and a second position. A vibration motor may be disposed within the device to impart vibration to the device. Decorative indicia may be provided on the exterior of the device. In use, the injection device may provide sensory stimuli to distract from the pain and the anticipation thereof.
    Type: Application
    Filed: June 7, 2013
    Publication date: December 19, 2013
    Inventors: Lisa Moreno Dickinson, Michael Anthony Quick
  • Patent number: 8545444
    Abstract: A system for administering pain-free injections includes an electric current source having at least two electrodes attached adjacent an injection site, the electric current source producing a variable numbness pattern and providing a frame of reference for identifying a plurality of sub-areas of the injection site; and a probe applied to the plurality of sub-areas of the injection site for pain-response testing, wherein one or more areas of numbness in the variable numbness pattern are identifiable according to the plurality of sub-areas of the injection site. A fence may be removably applied to the injection site and provide a frame of reference for identifying a plurality of sub-areas of the injection site, and may aid in identifying one or more areas of numbness in the variable numbness pattern. The fence may be removably applied to the injection site via a belt or manual pressure.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: October 1, 2013
    Inventor: Walter T. Perkins
  • Publication number: 20130253428
    Abstract: An apparatus is provided for performing an injection, the apparatus including a front end, a vibrator mechanism selectively vibrating the front end during an injection and a syringe holder holding a syringe during an injection through the front end while the front end is vibrated.
    Type: Application
    Filed: May 24, 2013
    Publication date: September 26, 2013
    Inventor: Steve FALLEK
  • Patent number: 8535275
    Abstract: A topical anesthetic dispenser is releasably attachable to a pre-filled disposable syringe. A clip receives a barrel of the syringe. The clip includes a receptacle portion receiving a pre-filled cannister of a topical numbing agent, wherein the cannister includes a generally cylindrical chamber portion receivable within the receptacle portion of the clip and a distal neck portion having an outlet allowing contents of the cannister to be dispensed. A dispenser attached to the distal neck portion of the cannister includes an elongated flexible tube surrounded by a rigid tube for at least a portion of a length of the elongated flexible tube. A pivotable lever carries a tube compressor including a pinching member extending through an opening in the rigid tube and spring biased to a position at which the pinching member pinches closed an elongated passageway through the flexible tube.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: September 17, 2013
    Inventor: Marc J. Salzman
  • Patent number: 8535276
    Abstract: A topical anesthetic dispenser is releasably attachable to a pre-filled disposable syringe. A pair of clips receive a barrel of the syringe. The clips are on a housing receiving a pre-filled cannister of a topical numbing agent and including a chamber. The cannister includes an aerosol dispensing valve actuated by a button which when pressed moves the cannister with respect to an actuator for the valve.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: September 17, 2013
    Inventor: Marc J. Salzman
  • Publication number: 20130231611
    Abstract: This disclosure relates generally to electrosurgical methods and devices. In some embodiments, an electrosurgical system/device is provided suitable for applying phase controlled RF energy to a treatment site. The electrosurgical device comprises a multi-electrode electrosurgical probe electrically coupled to a plurality of RF generators. Also provided are methods of use of such an electrosurgical device, as well as other electrosurgical devices. The methods and devices disclosed herein find utility, for example, in the field of medicine.
    Type: Application
    Filed: April 18, 2013
    Publication date: September 5, 2013
    Inventors: Daniel Lischinsky, Yoram Harth
  • Publication number: 20130226144
    Abstract: A method for starting an intravenous fluid line (IV) is disclosed where a combination of a syringe body with hypodermic needle, a dual ampoule with separate reservoirs for bicarbonate and an anaesthetic, a trocar and a cannula are configured so that the steps of injecting a wheal of a buffered anaesthetic, retracting the needle tip, lancing a vein with the trocar, and withdrawing the trocar tip so that the cannula remains in place in the vein may be accomplished in a single coordinated action by one skilled in the method, such as with one hand while the other hand performs manipulations on the vein and IV site.
    Type: Application
    Filed: April 6, 2013
    Publication date: August 29, 2013
    Applicant: Jeanne Diane Milligan
    Inventor: Jeanne Diane Milligan
  • Publication number: 20130184678
    Abstract: In one aspect, a dual action syringe includes an external body having a distal end defining an anesthetic gel receptive concavity surrounding a needle passage through the distal end. The external body also includes a proximal end defining a plunger receptive passage. An internal body is slidably disposed in the external body. The internal body receives a needle in a distal end of the internal body and an anesthetic carpule to provide fluid flow communication between the carpule and the needle in response to pressure on the plunger. A biasing member is disposed in the external body, between the external body and the internal body, biasing a distal end of the needle away from the distal end of the external body into the external body; whereby, pressure on the plunger first moves the needle through the needle passage and subsequently provides fluid flow communication between the carpule and the needle.
    Type: Application
    Filed: October 11, 2010
    Publication date: July 18, 2013
    Applicant: KING SAUD UNIVERSITY
    Inventors: Mohiddin Rida Dimashkieh, Mohammad Ibrahim Al Obaida
  • Patent number: 8372047
    Abstract: A system and method of topically applying an anesthetic, or other medication, to one or both lips of the mouth. An applicator device is provided that has a curved first wall, a curved second wall, and a horizontal shelf that joins the first wall to the second wall. The first wall, the second wall and the horizontal shelf combine to define either one or two curved lip compartments. A volume of the anesthetic, or other medication, is placed within the curved lip compartments. The applicator device is partially placed in a person's mouth so that the second wall is positioned between the back of the lips and in front of the teeth. While in this position, the lip of the user passes into the curved lip compartment and is contacted by the anesthetic.
    Type: Grant
    Filed: February 2, 2011
    Date of Patent: February 12, 2013
    Inventor: Otto J. Placik
  • Publication number: 20120302956
    Abstract: A means and a method is disclosed to diminish or eliminate the pain associated with a sharp object penetrating the skin, during such procedures as an injection, biopsy, or deriving a blood sample. To this end, repeated tapping, pressing, or rubbing or vibrating is performed over the skin at or near the site of penetration of the sharp object in conjunction with applying electricity on the skin. The invention discloses a method of using a skin-puncturing means, with enhanced features, to provide local anesthesia at the site of penetration of a sharp object.
    Type: Application
    Filed: July 17, 2012
    Publication date: November 29, 2012
    Inventor: Pourang Bral
  • Publication number: 20120253314
    Abstract: A palm-controlled device is disclosed for injection of a substance into an organism. The device includes a palm-receiving surface for receiving a palm of a hand, the palm receiving surface being shaped so that the palm is substantially parallel to a surface of an injection site of the organism while operating the device. The palm receiving surface can also be shaped so that the palm is substantially perpendicular to a surface of the injection site. The device also includes an injector having at least one pre-filled syringe, the palm-receiving surface being cooperative with the injector such that when pressure is applied to the palm-receiving surface, the injector is actuated so as to inject contents of the at least one pre-filled syringe. Actuation of the injector is by gradual pressure; not sudden motion. Single or multiple doses of same or different medications can be included in a single injector.
    Type: Application
    Filed: March 30, 2011
    Publication date: October 4, 2012
    Inventors: Ziv Harish, Saac Rubinstein, Russ Weinzimmer, Ehud Arbit
  • Publication number: 20120209246
    Abstract: A system for administering pain-free injections includes an electric current source having at least two electrodes attached adjacent an injection site, the electric current source producing a variable numbness pattern and providing a frame of reference for identifying a plurality of sub-areas of the injection site; and a probe applied to the plurality of sub-areas of the injection site for pain-response testing, wherein one or more areas of numbness in the variable numbness pattern are identifiable according to the plurality of sub-areas of the injection site. A fence may be removably applied to the injection site and provide a frame of reference for identifying a plurality of sub-areas of the injection site, and may aid in identifying one or more areas of numbness in the variable numbness pattern. The fence may be removably applied to the injection site via a belt or manual pressure.
    Type: Application
    Filed: February 16, 2011
    Publication date: August 16, 2012
    Inventor: Walter T. Perkins
  • Publication number: 20120179099
    Abstract: A device that is used to reduce the pain of a needle stick to a person, the device having a casing containing a vibratory device and a temperature reducing device, and a method for using the device to reduce the pain of a needle stick by applying both thermal and vibration analgesia to a subject during a needle stick.
    Type: Application
    Filed: March 21, 2012
    Publication date: July 12, 2012
    Applicant: MMJ Labs LLC
    Inventors: Amy L. Baxter, Louis A. Calderon
  • Patent number: 8216190
    Abstract: An improved method and apparatus is provided as a system to deliver a composition, preferably a medical or pharmaceutical composition or active, through the stratum corneum of skin, without introducing bleeding or damage to tissue, and absent pain or other trauma. The dimensions and shapes of the microelements are controlled so as to control the penetration depth into the skin. The microelements can be “hollow” such that passageways are created therethrough to allow the composition to flow from a chamber, through the microelements, and into the skin. Alternatively, the microelements can be “solid,” and the composition is applied directly to the skin just before or just after the microelements are applied to the skin surface to create the openings in the stratum corneum.
    Type: Grant
    Filed: February 9, 2006
    Date of Patent: July 10, 2012
    Assignee: Corium International, Inc.
    Inventors: Vladimir Gartstein, Faiz Feisal Sherman
  • Publication number: 20120130340
    Abstract: An automatic fluid injector (10, 66, or 76) having a coolant-absorbent pad (24) for pressing onto a tissue site for desensitization. When the injector (10, 66, 76) is pressed further toward the tissue site, the contained fluid is pressurized, and an enclosed needle (16) moves distally to penetrate a distal wall of injector (10, 66, 76). While needle (16) is being repositioned distally, the pressurized fluid is blocked from flowing into needle (16). The fluid blockage prevents the fluid from inadvertently warming the cold, desensitizing pad (24) and causing the patient to experience pain during needle (16) penetration. When needle (16) penetrates to a preset depth, and is sealed in the tissues, then the pressurized fluid is unblocked, and flows automatically through needle (16). In another embodiment, an instrument (46) having a coolant-absorbent felt (52) is able to unobstructably desensitize tissues prior to penetration with sharps.
    Type: Application
    Filed: November 19, 2010
    Publication date: May 24, 2012
    Inventor: Eric J. Knutson
  • Publication number: 20120070799
    Abstract: An apparatus and a method for reducing pain and the discomfort experienced by a patient as a consequence of a needle stick during the administration of an injection. The pain-reducing apparatus includes a handle and a disposable fork detachably connected thereto. The fork has a pair of outstretched fingers that are separated from one another by a gap at which the injection site is located. Vibrations applied to the fork from the handle are transmitted from the fingers of the fork to the patient's tissue or skin surrounding the injection site. The vibrations desensitize the patient's tissue/skin during the administration of the injection.
    Type: Application
    Filed: September 21, 2010
    Publication date: March 22, 2012
    Inventor: Mark Metcalf
  • Publication number: 20120065487
    Abstract: The various embodiments disclosed herein are devices that deliver electrical stimulation and/or vibration stimulation to the surface of skin in proximity to insulin injections and/or glucose testing in order to decrease or eliminate the pain of these procedures.
    Type: Application
    Filed: September 7, 2011
    Publication date: March 15, 2012
    Applicant: Innova Medical Design LLC
    Inventors: Timothy O'Malley, Rommel P. Vallero
  • Publication number: 20120010529
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood, from subjects, e.g., to the skin and/or from the skin. In one aspect, the present invention is generally directed to devices and methods for receiving blood from a subject, e.g., from the skin, using devices including a substance transfer component (which may contain, for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In certain embodiments, substances may be received from and/or delivered to the subject with relatively little pain. The pain may be assessed, to for example, using pain scales such as the Wong-Baker FACES Pain Scale. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject.
    Type: Application
    Filed: June 22, 2011
    Publication date: January 12, 2012
    Applicant: Seventh Sense Biosystems, Inc.
    Inventors: Donald E. Chickering, III, Howard Bernstein, Shawn Davis, Ramin Haghgooie, Douglas A. Levinson, Mark Michelman, Ping Gong
  • Publication number: 20110313391
    Abstract: An exemplary insulin infusion set that further provides one or more set elements including the hub, hub adhesive, fluid line tubeset, connectors, catheters and insertion needles which can be impregnated with, coated with, or otherwise configured to contain and administer an anesthetic at the insertion and set placement locations to minimize user discomfort and the risk of complications associated with the use of infusion sets. To do so, the system and method provides steps for mixing at a step (22) at least two of a solvent, an anesthetic, and a lubricant, applying the mixed compound as a coating to at least one surface of the infusion set, patch pump, or an element thereof at a step (24), and then substantially removing the solvent after coating at a step (26) to provide at least one of an anesthetic layer and a lubricant layer upon the infusion set, patch pump, or an element thereof.
    Type: Application
    Filed: January 26, 2010
    Publication date: December 22, 2011
    Inventors: Keith N. Knapp, II, Joshua Horvath
  • Publication number: 20110245769
    Abstract: Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture also includes a container coupled to the elongated body of the penetrating instrument. The container provides at least one chamber. Finally, the article of manufacture includes a nozzle connected to the container and configured to dispense pressurized content of the container responsive to activating a trigger communicating with the nozzle.
    Type: Application
    Filed: June 20, 2011
    Publication date: October 6, 2011
    Inventor: Michael Wycoki
  • Publication number: 20110196299
    Abstract: There is provided a structure of a needle for a syringe and, more particularly, to a needle connected to a medical syringe variously used for an intramuscular injection, an intravenous injection, an injection of Ringer's solution, or the others, which comprises a groove or protrusion in diverse shapes formed on the surface of the needle, whereby the needle is easily inserted to reduce pain and irritation when an injection is administered and the needle is prevented from being off an injection direction to inject medicine into a desired part, without any error when injections are administered into a muscle and a vein.
    Type: Application
    Filed: October 25, 2008
    Publication date: August 11, 2011
    Inventor: Youn-Sung Kim
  • Publication number: 20110112477
    Abstract: A preferred method to obtain painless or near painless needle 8 penetration is disclosed to be in the following manner: Applying electric current using a TENS device simultaneously with tapping the injection site for 30 to 60 seconds at a rate of about one strike per second, followed by a rapid needle 8 penetration into the skin 2.
    Type: Application
    Filed: November 12, 2009
    Publication date: May 12, 2011
    Inventor: Pourang Bral
  • Publication number: 20110098634
    Abstract: Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture further includes an attachment connector to couple the container to the housing of the penetrating instrument, where the attachment connector includes a circular connector body and a connector arm, the connector arm affixed to a spray housing of the dispensing device. The container provides at least one chamber.
    Type: Application
    Filed: December 30, 2010
    Publication date: April 28, 2011
    Inventor: Michael Wycoki
  • Publication number: 20110060310
    Abstract: The delivery of biopharmaceutical and other therapeutic agents parenterally to an animal via a minimally invasive, low pain administration is provided. The agents are delivered to the patient via, e.g., the epidermal, dermal, or subcutaneous layer of the skin in a concentrated fours of injectable paste of slurry.
    Type: Application
    Filed: November 16, 2010
    Publication date: March 10, 2011
    Inventors: Steven Prestrelski, Kevin Brodbeck
  • Patent number: 7883488
    Abstract: Described herein are transdermal delivery devices composed of at least one resealable injection port and at least one local anesthetic reservoir. The device effectively delivers anesthetic to the skin of the subject prior to puncturing the skin by syringes, needle sticks, or other instruments intended to be inserted into the skin. In addition, this device can be used to deliver various therapeutic agents for either locally or systemically.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: February 8, 2011
    Inventors: Totada R. Shantha, Jessica Shantha, Erica Shantha, Lauren Shantha
  • Patent number: 7883487
    Abstract: Described herein are transdermal delivery devices composed of at least one re-sealable injection port and at least one local anesthetic reservoir. The device effectively delivers anesthetic to the skin of the subject prior to puncturing the skin by syringes, needle sticks, or other instruments intended to be inserted into the skin. In addition, this device can be used to deliver various therapeutic agents for either locally or systemically.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: February 8, 2011
    Inventors: Totada R. Shantha, Jessica Shantha, Erica Shantha, Lauren Shantha
  • Patent number: 7842007
    Abstract: Apparatus (8) and methods are provided for facilitating medical procedures, such as providing injections to human or animal patients. The apparatus and methods mitigate against discomfort and/or pain often experienced by a patient receiving an injection for a therapeutic or a cosmetic purpose. The apparatus and methods are effective to isolate a surface area of a human or animal body, even an irregularly shaped surface area of a body, for enabling localized preparation of the skin, for example for localized cooling of the skin.
    Type: Grant
    Filed: April 29, 2005
    Date of Patent: November 30, 2010
    Inventors: Burrell E. Clawson, Richard A. Weiss
  • Publication number: 20100211010
    Abstract: Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture also includes a container coupled to the elongated body of the penetrating instrument. The container provides at least one chamber. Finally, the article of manufacture includes a nozzle connected to the container and configured to dispense pressurized content of the container responsive to activating a trigger communicating with the nozzle.
    Type: Application
    Filed: February 18, 2009
    Publication date: August 19, 2010
    Inventor: Michael Wycoki