Material Introduced Or Removed Through Conduit, Holder, Or Implantable Reservoir Inserted In Body Patents (Class 604/93.01)
  • Patent number: 11826535
    Abstract: Various exemplary devices and methods are provided for performing surgical procedures. In general, one or more adjuncts can be used in conjunction with surgical instruments. The adjunct(s) can have medicant(s) thereon and/or therein. The medicant(s) can vary depending on the desired effect of the medicant(s) on surrounding tissue. As a non-limiting example, medicant(s) can be provided to influence hemostasis, inflammation, macrophages, and/or fibroblasts. When used in conjunction with a surgical stapler, the adjunct(s) can be disposed between and/or on jaws of the stapler, incorporated into a staple cartridge disposed in the jaws, or otherwise placed in proximity to the staples. When staples are deployed, the adjunct(s) can remain at the treatment site with the staples.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: November 28, 2023
    Assignee: Cilag GmBH International
    Inventors: Jason L. Harris, Frederick E. Shelton, IV, Michael J. Vendely, Tamara S. Widenhouse
  • Patent number: 11819666
    Abstract: A modular drive train is selectively securable within a wearable injector. The drive train includes a chassis and a telescoping driving assembly mounted within the chassis. The driving assembly includes a first shaft rotatable relative to the chassis, and a second shaft connected with the first shaft and axially movable relative thereto. Rotation of the first shaft axially drives the second shaft. The chassis includes one of a bearing and an elastically expandable collar projecting axially forward into the chassis from a rear end thereof, and the first shaft includes the other of the bearing and the elastically expandable collar projecting axially rearwardly from a rear end thereof. The collar is configured to elastically snap over an interference element of the bearing, whereby engagement of the collar with the bearing axially secures the first shaft to the chassis and permits rotation of the first shaft about the bearing.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: November 21, 2023
    Assignee: West Pharma. Services IL, Ltd.
    Inventors: Yossi Bar-El, Gil Yigal, Reuven Y. Filman
  • Patent number: 11819326
    Abstract: A medical implant including a drug sensor and a global positioning system (GPS) module connected to a wireless network. The GPS module sends a location of the patient and optionally information of when patient uses an illegal drug when the sensor detects the drug within the patient's bloodstream.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: November 21, 2023
    Inventor: Jill Renee Donohoo
  • Patent number: 11744560
    Abstract: A sampling capsule is provided. The sampling capsule includes an enclosure, a sampling assembly, a sample drawing assembly and a control module. The sampling assembly includes a sample chamber arranged in the enclosure, an outer sampling port on the enclosure, a sampling tube connecting the outer sampling port and the sample chamber, and a sampling switch for opening or closing the connecting tube. The sample drawing assembly includes a sample drawing port on the enclosure and connected to the sample chamber, and a silicone plug fitted in the sample discharging port. The control module includes a microprocessor communicating with the sampling switch.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: September 5, 2023
    Inventors: Tianyi Yangdai, Yuhui Bao, Hangyu Peng, Fanhua Ming
  • Patent number: 11751448
    Abstract: A display device includes a substrate including a main display area, main display elements being in the main display area; a component area, auxiliary display elements and a transmission area being in the component area; and a peripheral area outside the main display area; an initialization voltage line in the main display area and extending in a first direction; a bottom metal layer in the component area between the substrate and the auxiliary display elements; and a bias line in the main display area and extending in the first direction, the bias line being connected to the bottom metal layer and being at a same layer as the initialization voltage line, wherein the bias line and the initialization voltage line are alternately arranged along a second direction crossing the first direction, in a first region of the main display area around the component area.
    Type: Grant
    Filed: March 30, 2021
    Date of Patent: September 5, 2023
    Assignee: Samsung Display Co., Ltd.
    Inventors: Youngsoo Yoon, Hyunji Kang, Dongeup Lee, Yunkyeong In, Hyunji Cha
  • Patent number: 11738106
    Abstract: A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: August 29, 2023
    Inventors: Markus Hemminger, Ulla Grauschopf, Frank Bamberg, Mayumi Bowen, Robert Müller, Flora Felsovalyi, Denny Christensen
  • Patent number: 11738120
    Abstract: Improved methods for synthesizing taurolidine, improved compositions or formulations comprising taurolidine and methods for reducing an amount of impurities in taurolidine are provided herein, among other things. The taurolidine may be substantially free of impurities. The taurolidine may be a polymorph, for example, Polymorph A or Polymorph B. The composition or formulation may comprise Low-Molecular-Weight (LMW) Heparin.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: August 29, 2023
    Assignee: CorMedix Inc.
    Inventor: Reyes M. Berrios
  • Patent number: 11730879
    Abstract: A computing device comprises a memory and a data interface for connecting to a corresponding interface in a storage assembly. The memory comprises instructions which, on connection with the storage assembly, cause a processor of the storage assembly to: detect, using a device sensor of the storage assembly, one or more medicament delivery devices stored in the storage assembly; and display, on a display screen provided on the storage assembly, information relating to a medicament stored in the storage assembly.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: August 22, 2023
    Assignee: Sanofi
    Inventor: Michael Helmer
  • Patent number: 11726092
    Abstract: The invention relates, in part, to methods of scoring a sample containing tumor tissue from a cancer patient. The score is representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: August 15, 2023
    Assignee: Novartis AG
    Inventors: Naveen Dakappagari, Thai Tran, Brian Little, Ju Young Kim, Jennifer Bordeaux
  • Patent number: 11717641
    Abstract: A catheter with a distal end that rotates through the conversion of linear motion to rotational motion, thus the distal end may be rotated without longitudinally advancing or retracting the distal end. The catheter includes a tube with a single helix or a dual chirality helix cut into the tube, a distal end segment, means for linear displacement of the helix, and means for coupling the junction point of the helix to the distal segment.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: August 8, 2023
    Assignee: MicroNovus, LLC
    Inventor: Brian Giles
  • Patent number: 11690523
    Abstract: The present invention provides a carotid blood pressure detection device, comprising: a first sensing unit, a second sensing unit, and a controller connected or coupled to the first sensing unit and the second sensing unit. The first sensing unit is disposed on a subject's neck and adjacent to a first position of the subject's carotid arteries. The second sensing unit is disposed on the subject's neck and adjacent to a second position of the subject's carotid arteries. The controller derives a mean arterial pressure of a section of the subject's carotid arteries that lies between the first position and the second position of the subject's carotid arteries from pulse wave data measured and obtained by the first sensing unit and pulse wave data measured and obtained by the second sensing unit.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: July 4, 2023
    Assignees: BIV MEDICAL, LTD.
    Inventor: Shiming Lin
  • Patent number: 11672921
    Abstract: A flexible collar including a rigid body having a cylindrical outer surface and a cylindrical inner surface concentrically aligned with respect to a common longitudinal axis, a top surface, and a bottom surface, the inner surface defining a bore from the top surface to the bottom surface, and each of the top and bottom surfaces having an endless pathway confined to a respective plane and circumscribing a respective edge of the inner surface. The flexible collar further includes at least one accordion region having a plurality of pivots, at least two of the pivots being radially spaced apart from the longitudinal axis at different distances, and the accordion region being configured to radially deform.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: June 13, 2023
    Assignee: West Pharmaceutical Services, Inc.
    Inventors: Terry McElroy, Colin Dowling, Patrick Dowling, Martin McGarry
  • Patent number: 11664107
    Abstract: Systems, devices and methods are disclosed for a prescription-regulated software application and an associated medical device. In some aspects, a smart medicine-injection device (e.g., smart insulin pen) is configured to be in communication with a patient's companion device (e.g., smartphone) having a software application (prescription app) that serves the patient as a complimentary medical device to the smart medicine-injection device, in which only certain features and functionalities of the prescription app are fully operable based on device pairing with the smart medicine-injection device to unlock medical device capabilities only available to the patient through prescription.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: May 30, 2023
    Inventors: Sean Saint, Jasper Benke
  • Patent number: 11654711
    Abstract: A writing tool includes a refill having an ink reservoir tube formed to be a straight cylinder whose wall thickness is less than 0.56 mm; and a writing tip or a relay member holding the writing tip attached to a first end of the ink reservoir tube, wherein the refill is detachably attached to a barrel, wherein in the refill, amounting strength between the writing tip or the relay member holding the writing tip and the ink reservoir tube is set higher than a mounting strength between the barrel and a connecting portion of the ink reservoir tube. There is provided a writing tool that can prevent the occurrence of a problem such as leakage of ink at a time of replacement of refills and perform replacement of refills smoothly.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: May 23, 2023
    Inventors: Takayuki Ikai, Seiichi Maruyama, Kiyoshi Iwamoto
  • Patent number: 11627982
    Abstract: A method and device handle having a slide assembly for controlling rotational speed of a catheter assembly under various rotational loads. The method includes setting a first current limit in a processor, activating the catheter assembly to rotate, calculating a current value in rotational period of a first current limit, updating a second current limit from the first current limit, and wherein the second current limit is lower than the first current limit.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: April 18, 2023
    Inventors: Yuki Masubuchi, Steve Woodard, Mansour Saleki
  • Patent number: 11623022
    Abstract: Composite nerve guides for nerve regeneration are provided, wherein the composite guide comprise a nerve graft and a nerve conduit continuing an active agent that promote axon regeneration. The devices can provide structural supports to guide nerve regeneration and locally deliver an active agent (e.g., glial cell-line derived neurotrophic factor (GDNF) and/or glial growth factor 2 (GGF2) to injured nervous system tissue upon implantation in a subject. Methods of treatment using such devices are also provided.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: April 11, 2023
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Kacey Gribbin Marra, Jacqueline Wittmer
  • Patent number: 11621072
    Abstract: A system, method, and computer program product for identifying device connections in a connection area includes receiving a plurality of physical parameters of a plurality of devices from a plurality of transmission sources in a connection area, wherein the plurality of physical parameters indicates physical states of the plurality of devices. At least one physical connection state is determined between the plurality of devices based on the plurality of physical parameters of the plurality of devices.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: April 4, 2023
    Assignee: Becton, Dickinson and Company
    Inventor: Erik Kurt Witt
  • Patent number: 11617800
    Abstract: A nanoparticle (NP)-peptide conjugate provides efficient steric hindrance/blockage of cellular membrane potassium (K+) channels to mediate depolarization of cellular membrane potential.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: April 4, 2023
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: James B. Delehanty, Megan Muroski, Eunkeu Oh, Jeffrey R. Deschamps
  • Patent number: 11612699
    Abstract: In one aspect, the disclosure relates to an injection device configured for expelling of a dose of a medicament. The injection device comprises a housing configured to accommodate a medicament reservoir, and a drive mechanism comprising an electric propulsion configured to mechanically interact with the medicament reservoir and configured to withdraw or to expel an amount of the medicament from the medicament reservoir. The injection device has at least a first interface directly or indirectly connected to the electric propulsion and configured to connect to a second interface of an auxiliary electronic device. The electric propulsion is controllable by the auxiliary electronic device when the first interface and the second interface are interconnected.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: March 28, 2023
    Assignee: Sanofi
    Inventor: Michael Helmer
  • Patent number: 11612686
    Abstract: Disclosed is a medical device component for delivering medication fluid to a patient. The medical device component includes a fluid infusion device to regulate delivery of medication fluid, a body-mountable base unit, and a top cover assembly that is removably couplable to the base unit and to the fluid infusion device. The base unit includes a cannula to deliver medication fluid under the control of the fluid infusion device, and a physiological analyte sensor to measure a physiological characteristic. The base unit also includes an electronics assembly electrically connected to sensor leads to obtain measurements in the analog domain, to convert measurements into digital sensor data, and to communicate conditioned digital sensor data to the fluid infusion device. The top cover assembly is configured to provide both fluid and electrical connections for the base unit, by way of an infusion tube having sensor conductors integrated therein or otherwise associated therewith.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: March 28, 2023
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Chia-Hung Chiu, Peter Schultz, Gayane R. Voskanyan, Hsifu Wang, Rebecca K. Gottlieb, Kenneth D. Warnock, Ricardo Juarez Martinez
  • Patent number: 11596496
    Abstract: A surgical device including a handle assembly, an elongated portion, at least one window, an end effector, and a shroud is disclosed. The at least one window extends through an outer wall of the elongated portion and is configured to allow fluid to travel therethrough from an interior portion of the elongated portion to ambient air. The end effector is configured to selectively engage a distal portion of the elongated portion. The shroud is affixed to the end effector and extends proximally therefrom. The shroud is configured to cover the at least one window when the end effector is engaged with the elongated portion.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: March 7, 2023
    Assignee: Covidien LP
    Inventors: David E. Valentine, Joseph Eisinger, Patrick Mozdzierz, Justin Williams
  • Patent number: 11589892
    Abstract: A surgical apparatus comprises a body, a user input feature, a shaft assembly, an end effector, and a blade cooling system. The end effector comprises a clamp arm and an ultrasonic blade that may be coupled with an ultrasonic transducer. The clamp arm is configured to pivot toward and away from the ultrasonic blade. The cooling system is operable to deliver liquid coolant to the ultrasonic blade to thereby cool the ultrasonic blade. The user input feature is operable to both actuate the clamp arm and actuate the cooling system.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: February 28, 2023
    Assignee: Cilag GmbH International
    Inventors: Michael J. Stokes, Scott R. Bingham, Ryan M. Asher, Charles J. Scheib, Rudolph H. Nobis, Frederick L. Estera, Benjamin D. Dickerson, Carl J. Draginoff, Jr., Jeffrey D. Messerly, David J. Cagle, Jacob S. Gee, William B. Weisenburgh, II, Omar E. Rios Perez, Chester O. Baxter, III, Karalyn R. Tellio, Benjamin M. Boyd, Rafael J. Ruiz Ortiz, Joël Fontannaz, Lukas S. Glutz, Amir Feriani, Emmanuel Gremion
  • Patent number: 11571164
    Abstract: Provided herein are systems and methods for monitoring one or more health or physiological parameters in a subject. The systems and methods may comprise a patch coupled to an injector. Data may be transmitted to a mobile device or remote server, where the data may be processed. Processed data may be used to inform a subject on a health or physiological condition.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: February 7, 2023
    Inventors: Michael D. Hooven, Matthew J. Huddleston, David Stefanchik, Rowan Converse, Kory Gunnerson, James Marous, Phillip Schultz, Benjamin Webb
  • Patent number: 11559626
    Abstract: An implantable glymphatic pump configured to flush metabolites from a brain parenchyma of a patient. The implantable glymphatic pump including at least one spinal catheter having a distal end configured to be positioned within an intrathecal space of a spine of a patient, at least one cranial catheter having a distal end configured to be positioned within a brain parenchyma of the patient, and an implantable pump configured to draw cerebrospinal fluid from the intrathecal space of the spine in the patient via the at least one spinal catheter, and reintroduce said cerebrospinal fluid to the brain parenchyma of the patient via the one or more cranial catheters to encourage a flow of the cerebrospinal fluid through the brain parenchyma.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: January 24, 2023
    Assignee: Medtronic, Inc.
    Inventor: Jeffrey P. Bodner
  • Patent number: 11504513
    Abstract: Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member; and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: November 22, 2022
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Danielle L. Clay, Lloyd Snyder, Jeffrey A. Soucia, Michael Merves, Antonio Belton, Sean Corrigan, Keith Grider, Michael Honsing Lau, Derek Leatzow
  • Patent number: 11497847
    Abstract: An on-body drug delivery device having a housing carried by a substrate. The substrate includes one or more cut-outs and/or one or more perforations to allow the substrate to better conform to the patient's body.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: November 15, 2022
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Sharon D. West, Vladlena Belozerova
  • Patent number: 11497841
    Abstract: A first method of forming a blood access hole includes: cutting a blood vessel; and connecting the cut blood vessel to a skin. A second method of forming a blood access hole includes: forming an opening in a skin; and connecting a blood vessel, at least a part of which is incised, to the opening. A third method of forming a blood access hole includes: connecting a blood vessel, at least a part of which is incised, to a skin, to open a part of an inner wall of the blood vessel to the atmosphere. A blood access hole 1 in which a blood vessel 10 inside a human body is directly connected to the skin 20 of the human body.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: November 15, 2022
    Inventor: Masanori Wakabayashi
  • Patent number: 11478236
    Abstract: The present disclosure relates to devices and methods for delivery of a ferrofluid to a targeted treatment site, such as delivery of a ferroadhesive to a pathological fistula to occlude the fistula. A device includes a catheter having a lumen and a distal opening. A hollow solenoid is coupled to a distal section of the catheter, and a hollow core of the solenoid allows passage of a ferrofluid through the catheter and through the hollow core so that it may exit past the distal end of the hollow solenoid. The solenoid may be selectively actuated to maintain or control the position of the delivered ferrofluid.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: October 25, 2022
    Assignee: University of Kansas
    Inventors: Stephen Clifford Waller, Alyssa Kirk Rollando, Richard Kevin Gilroy, Philip Lee Johnson, James Marion Stiles, Sara Ellen Wilson
  • Patent number: 11478273
    Abstract: The present invention provide a puncture instrument capable of administering (supplying) a drug solution. The puncture instrument includes a puncture tip section (2); a first tubular body (3) connected to the puncture tip section (2) at the distal end; and an outer tubular body (5) at least partially covering the first tubular body (3). The first tubular body (3) is formed to be rotatable around an axis along the longitudinal direction. The first tubular body (3) has an outer diameter smaller than an inner diameter of the outer tubular body (5). A drug solution supply path (5a) is provided on the outside of the first tubular body (3).
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: October 25, 2022
    Assignee: TRANSELL CO., LTD.
    Inventors: Shuji Nakamura, Ken Masamune, Kohei Miki, Katsuyuki Sado, Hirokazu Takagawa, Fumiya Iwashima, Akihiro Nabeshima
  • Patent number: 11464960
    Abstract: A low-profile access port for subcutaneous implantation within a patient. The access port can include a set of receiving cups which can be placed in fluid communication with a catheter. The set of receiving cups can provide a greater skin surface with which to access the port to avoid repeated penetrations at a single locus, such as during consecutive dialysis treatments. The access port can alternatively include needle penetrable arms or elongate chambers that also have a slim, low profile. The access port can include a needle guide to direct subsequent needle access to different insertion points to permit healing at the previous insertion points. The access port can be formed of a modular construction with a first conduit, a second conduit, and an outer shell. The outer shell can include a proximal portion and a distal portion. The access port can include a stem assembly and a locking member.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: October 11, 2022
    Assignee: C. R. Bard, Inc.
    Inventors: Brenda L. Fedor, Jason R. Stats, Michael A. Randall, Chad C. Van Liere, Jeremy B. Cox
  • Patent number: 11464898
    Abstract: A flushing apparatus according to embodiments of the present disclosure includes: a main body configured to connect a connection pipe for guiding a hazardous medicinal liquid harmful to a human body when exposed to an ambient air and a patient connection module for injecting the hazardous medicinal liquid into a patient, the main body configured to form a first flow path for guiding the hazardous medicinal liquid from the connection pipe to the patient connection module, the main body including a flushing portion forming a second flow path connected to a predetermined connection point located between both ends of the first flow path; and a flow rate reduction part disposed at upstream side of the connection point in the first flow path and configured to reduce a flow rate of the hazardous medicinal liquid flowing through the first flow path. The present disclosure shows various embodiments of the flushing apparatus.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: October 11, 2022
    Inventor: Yong Hyun Kim
  • Patent number: 11457924
    Abstract: An endovascular device, including an elongated flexible sheath defining a lumen with an inner opening sized for enabling selective advancement of an endovascular instrument therethrough, the sheath having at least a first region and a second region; an electrode within the first region of the sheath; and a constrictor associated with the first region of the sheath, the constrictor being configured, while at least the first region and the second region of the sheath are positioned within a body and in response to an input received from outside the body, to reversibly narrow the lumen of the sheath in an area adjacent the electrode to thereby bring the electrode into contact with an adjacent portion of the endovascular instrument.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: October 4, 2022
    Assignee: RAPID MEDICAL LTD.
    Inventors: Eyal Kaufman, Matan Gedulter, Ronen Eckhouse
  • Patent number: 11439767
    Abstract: A drug delivery system having an end-of-dose detection arrangement for injecting a medicament. The system including a container configured to receive a medicament, a drive assembly which, upon actuation, is configured to expel the medicament from the container, a needle for injecting the medicament to a patient, a needle actuator assembly comprising a movable portion biased by a biasing member and configured to move the needle between a pre-use position, a use positon for delivery of the medicament to the patient, and a post-use position after delivery of the medicament is completed, and a tube in fluid communication with the container and the needle, the tube comprising an expandable portion having an expanded state and a non-expanded state, wherein the expandable portion is configured to be in the expanded state upon actuation of the drive assembly and a non-expanded state when the needle is in the post-use positon.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: September 13, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: David E. Booth, Michael Vincent Quinn
  • Patent number: 11419978
    Abstract: Subcutaneous access hub embodiments are discussed herein that include housing embodiments having a plurality of cannula ports and a fluid passageway network that allows fluid communication between a fluid source and the plurality of cannula access ports. Such a configuration may allow a user such as a patient or clinician to releasably secure the housing to an outside surface of the patient's skin. Multiple locations on the patient's skin may then be accessed for deployment of one or more delivery cannulas via a plurality of cannula ports for delivery of fluid and from the fluid source to multiple subcutaneous locations below the patient's skin and timely movement of cannula access in the patient's skin without the need for relocating the housing.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: August 23, 2022
    Assignee: QUASURAS, INC.
    Inventors: Paul M. DiPerna, Marc Goldman
  • Patent number: 11406759
    Abstract: A method for connecting a force sensor to a circuit board is disclosed. A circuit board having first and second conductive leads located on the same surface of the circuit board is provided. Also provided is a force sensor with a first flexible contact tab having a first contact pad and a second flexible contact tab having a second contact pad. The first contact pad is arranged to face the first conductive lead. A first conductive rubber element establishes an electrical connection between the first contact pad and the first conductive lead, and the second contact pad and the second conductive lead are arranged to face in the same direction. A second conductive rubber element establishes an electrical connection between the second contact pad and the second conductive lead. Also disclosed are an associated device for determining fluid pressure in an insulin pump and an insulin pump.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: August 9, 2022
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Hans List
  • Patent number: 11376374
    Abstract: Provided are a medicine injecting tip, which injects a medicine into a hole in a skin formed by a needle while invading the needle to a preset depth of a deep portion of the skin, a hand piece equipped with the medicine injecting tip, and a skin treatment device using the medicine injecting tip. The medicine injecting tip includes a cylinder, a plunger that reciprocates downward and upward, and has a first space and a second space formed inside the cylinder, and a needle disposed in the plunger and disposed in the second space of the cylinder. The needle is inserted into a skin and a negative pressure state is formed in the second space when the plunger moves downward, and the needle is discharged from the skin and a positive pressure state is formed in the second space, when the plunger moves upward.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: July 5, 2022
    Inventor: Kyoung Ho An
  • Patent number: 11364062
    Abstract: Medical devices for injecting materials into patients are disclosed. The devices can include a body having a handle and a lever. The devices can also include a delivery tube comprising a passageway along a longitudinal axis and a nozzle with an opening, the delivery tube configured to couple with a distal end of the body. A driving rod can be inserted into the body and extend into the passageway, such that the lever can move the driving rod distally when the lever is actuated toward the handle. Methods of using the material delivery device are also disclosed.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: June 21, 2022
    Assignee: Spinal Elements, Inc.
    Inventors: Markanthony Flores, Daniel Zatta
  • Patent number: 11266823
    Abstract: Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: March 8, 2022
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Matthew William Yavorsky, Edgardo C. Halili, Eric M. Lorenzen
  • Patent number: 11229741
    Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir; and a drive mechanism for driving fluid from the reservoir, the drive mechanism comprising a plunger received in the reservoir; a leadscrew extending from the plunger; a nut threadably engaged with the leadscrew; a drive wheel; and a clutch mechanism coupled to the drive wheel, wherein the clutch mechanism is configured to allow the nut to pass through when disengaged and is configured to grip the nut when engaged such that the drive wheel rotates the nut to advance the drive rod and the plunger into the reservoir.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: January 25, 2022
    Inventors: Steven Diianni, Ian McLaughlin, Jason Brian O'Connor, Robert Campbell, Kevin Schmid
  • Patent number: 11203139
    Abstract: An adhesive patch is secured to an infusion set, patch pump or other on-body medical device by an overmolding process during manufacture of the medical device, or during manufacture of a portion of the medical device, without the need for a separate adhesive. This provides a more secure connection between the patch and the medical device, and reduces the required number of adhesive layers from two (skin attachment side and device attachment side) to one (skin attachment side only), thereby simplifying the design and manufacture of the patch.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: December 21, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Jeffrey Reed, John Knight, Scott Townsend
  • Patent number: 11191947
    Abstract: A fluid treatment system for a percutaneous cable and methods of assembly and use are described herein. In one aspect, the fluid treatment system includes a delivery tube comprising a distal end and a proximal end. The distal end is configured to surround at least a portion of the percutaneous cable. The percutaneous cable extends from within a patient to outside the patient through tissue at an exit site. The proximal end is connectable to a fluid source. Fluid from the fluid source is configured to be delivered to the exit site through the delivery tube. The fluid treatment system includes an anchor coupleable to the percutaneous cable to secure the percutaneous cable to the tissue at the exit site.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: December 7, 2021
    Assignee: TC1 LLC
    Inventors: Christian Schade, Justin Callaway, Cori Pierce
  • Patent number: 11141164
    Abstract: A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: October 12, 2021
    Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University System
    Inventors: Jason M. Ortega, William J. Benett, Ward Small, Thomas S. Wilson, Duncan J. Maitland, Jonathan Hartman
  • Patent number: 11116948
    Abstract: Rapid exchange balloon catheter, and applications thereof. The balloon catheter includes a shaft and a guidewire channel. Shaft includes infusion and inflation walls. Infusion wall encloses an infusion lumen and comprises fluid inlet and fluid outlet located distally to fluid inlet. The inflation lumen extending axially therealong opened at a distal end thereof into an inner volume of a dilatation balloon. Guidewire channel is sized to closely fit over a pre-scribed guidewire for allowing unhindered passing therethrough with the guidewire. Guidewire channel includes a channel distal end protruding distally from the balloon with a distal guidewire opening, and a channel proximal end with a proximal guidewire opening at the shaft between fluid inlet and fluid outlet. Applications include methods for angioplasty and revascularization in which a single balloon catheter is used for dilatation and/or occlusion, and for delivering fluid proximally to the balloon.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: September 14, 2021
    Inventors: Michael Gabriel Tal, Ilan Carmel, Ronny Winshtein
  • Patent number: 11109800
    Abstract: Provided herein are systems and methods for monitoring one or more health or physiological parameters in a subject. The systems and methods may comprise a patch coupled to an injector. Data may be transmitted to a mobile device or remote server, where the data may be processed. Processed data may be used to inform a subject on a health or physiological condition.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: September 7, 2021
    Inventors: Michael D. Hooven, Matthew J. Huddleston, David Stefanchik, Rowan Converse, Kory Gunnerson, James Marous, Phillip Schultz, Benjamin Webb
  • Patent number: 11083558
    Abstract: Disclosed is a catcher (100), comprising an catching ring (11) and at least one connecting rod (15), wherein both ends of the connecting rod (15) are connected to the catching ring (11), and the connecting line between the two ends of the connecting rod (15) is located within the catching ring (11). Compared with catching loops in the prior art, the catching ring (11) of the catcher (100) is a ring structure supported by the connecting rod (15), thereby having a relatively high stability and not easily being deformed under erosion by a blood flow, so as to facilitate accurate positioning by a doctor during clinical operations and improve the success rate of withdrawal.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: August 10, 2021
    Assignee: Lifetech Scientific (Shenzhen) Co. Ltd.
    Inventors: Zhuo Chen, Hong-bing Luo
  • Patent number: 11040138
    Abstract: Drug delivery system, injection device, transfer apparatus, vial holder and method of administering and transferring are disclosed. The system may include transfer apparatus and an injection device. The transfer apparatus may have receiving stations for a drug source, such as a vial or vial holder, and for an injection device, and fluid flow pathways for transferring drugs from the source into the injection device. The injection device may include an expandable elastic bladder and an injection cannula that is movable between a plurality of positions.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: June 22, 2021
    Assignee: Enable Injections, Inc.
    Inventors: Michael D. Hooven, Matthew J. Huddleston, Joetta Renee Palmer, David Stefanchik
  • Patent number: 11020573
    Abstract: A modular dilation device (100) is provided for inserting multiple dilators into a target patient tissue site. The modular dilation device includes a first dilator (104) and a second dilator (530). The first dilator has a first dilator distal end (108) and a first dilator inner lumen (114). The first dilator has a first dilator side wall opening (118). The first dilator distal end has a first dilator open tip (116). The first dilator has a first dilator open slit (120). The first dilator open slit extends between the first dilator side wall opening and the first dilator open tip. The second dilator has a second dilator distal end and a second dilator inner lumen. The second dilator distal end has a second dilator open tip. When the second dilator is joined to the first dilator, the second dilator open tip is adjacent to the first dilator side wall opening.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: June 1, 2021
    Inventor: Karunakaravel Karuppasamy
  • Patent number: 11013855
    Abstract: Embodiments may include a method of delivering a drug. The method may include removing or releasing a structure from a patch-pump assembly. The patch-pump assembly may include a sealed prefilled drug-reservoir, a fluid passageway, a cannula-containing assembly, and a penetrator. The method may also include penetrating the sealed prefilled drug-reservoir containing the drug to establish fluid communication between the sealed prefilled drug-reservoir and a fluid passageway by removing or releasing the structure. The method may further include flowing the drug from the prefilled drug-reservoir to the fluid passageway. In addition, the method may include flowing the drug from the fluid passageway to a cannula-containing assembly. Furthermore, the method may include delivering the drug subcutaneously to a subject using the cannula-containing assembly.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: May 25, 2021
    Assignee: STEADYMED LTD.
    Inventor: Nir Rotem
  • Patent number: 10987467
    Abstract: A cannula insertion device is disclosed. The device includes a needle carriage, a rail device on which the needle carriage is slidable, a yoke having a channel, a linkage connected to the needle carriage and extending into the channel, a torsion spring with one end connected to the linkage, and locking device for locking the torsion spring in tension and maintaining the needle carriage and the linkage in a locked position prior to activation. Upon release of the locking device, the tension of the torsion spring is released, which causes the linkage to move in the channel and slide the needle carriage along the rail device. A catheter carriage may also be provided for actuation by the linkage.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: April 27, 2021
    Inventors: Russell Cole, Alyssa Jackson
  • Patent number: 10943163
    Abstract: Technologies are described for delivering an active agent using an ingestible pill device, securing medication package content, and monitoring the medication package content. Examples of the technology include using an ingestible pill device to deliver an active agent, where release of the active agent can be based on patient authentication, analyzing sensor data to determine a condition for releasing the active agent, analyzing image data to identify a release point, etc. Examples of the technology also include using a monitoring device to secure a medication package using a cover and locking device, monitoring the medication package to detect access to the medication package, and tracking access to the medication package to determine medication adherence.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: March 9, 2021
    Assignee: Intel Corporation
    Inventors: Ariel Moshkovitz, Oren Arad, Tomer Rider, Tamara Gaidar, Oleg Pogorelik