Treating Material Introduced Into Or Removed From Body Orifice, Or Inserted Or Removed Subcutaneously Other Than By Diffusing Through Skin Patents (Class 604/48)
  • Patent number: 12090284
    Abstract: Tissue puncture devices, and systems and methods for accessing tissue (e.g., cardiovascular tissue) according to the present disclosure may include a tubular sheath extending along a longitudinal axis, the tubular sheath having a proximal end and a distal end, a needle disposed coaxially in the sheath, the needle having a proximal end and a distal end and being movable along the longitudinal axis of sheath, and a needle control mechanism disposed at the proximal end of the needle, the needle control mechanism being configured to lock the distal end of the needle in a first position retracted within the distal end of the sheath, and release the needle to an unlocked second position such that the distal end of the needle is extendable beyond the distal end of the sheath.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: September 17, 2024
    Assignee: BOSTO SCIENTIFIC SCIMED, INC.
    Inventors: Lance A. Freeseman, James P. Rohl, Joel T. Eggert, Eric M. Petersen, Craig M. Wilson, Douglas D. Pagoria, Todd College
  • Patent number: 11964128
    Abstract: A medical liquid injection device is provided. The medical liquid injection device includes a base body, a needle assembly mounted on the base body, a reservoir fluidly connected to the needle assembly and having a guide groove on an inner surface, and a driving unit configured to move a plunger disposed inside the reservoir.
    Type: Grant
    Filed: March 2, 2023
    Date of Patent: April 23, 2024
    Assignee: EOFLOW CO., LTD.
    Inventors: Kiung Kim, Wonkyung Bang, Daejong Park, Seungha Kim
  • Patent number: 11883621
    Abstract: According to some embodiments, a system for treating skin includes a handpiece assembly comprising a tip and a main body portion, the main body portion comprising an interior cavity and at least one canister configured to store at least one of a treatment material and a waste material. The treatment material and/or the waste material is in fluid communication with the tip.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: January 30, 2024
    Assignee: HydraFacial LLC
    Inventors: Roger Ignon, Ed F. Nicolas
  • Patent number: 11877753
    Abstract: Delivery systems for liquid embolics and methods of using them are disclosed. The devices generally include a catheter and one or more retention elements to limit migration of the liquid embolic to non-target sites.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: January 23, 2024
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Joseph Connolly, Gary Pederson, Mary-Claire Anderson, Patrick Haverkost, David Raab, Mark Smith
  • Patent number: 11819662
    Abstract: The invention relates to a pumping device including a pump (1) comprising—a pumping chamber (11) having a variable volume, —an inlet (2) communicating with the pumping chamber (11) and comprising a valve, —an outlet (5) communicating with the pumping chamber and comprising a valve, —an actuator adapted to change the volume of the pumping chamber, —a fluidic pathway comprising said inlet (2), said pumping chamber (11), said outlet (5) and a downstream line (7) situated downstream of the outlet valve, —a pressure sensor (4) for measuring the pressure between the valves of said pathway, —processing means for processing the received pressure data from the pressure sensor (4). The invention also covers a method for detecting a dysfunction in a pumping device as defined above.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: November 21, 2023
    Assignee: DEBIOTECH S.A.
    Inventors: Eric Chappel, Niklaus Schneeberger, Frédéric Neftel
  • Patent number: 11628124
    Abstract: A system for feeding and evacuation has a feeding tube in place into a subject's stomach cavity, having a Luer-Lock compatible female connector on an outboard end, a feed source, a unique Lopez valve having a conventional connector on one end and a male Luer-Lock connector on the other end in place of the conventional tapered connector, a suction tube coupled to a suction source, the suction tube having a connector compatible with the conventional connector of the conventional Lopez valve on an end away from the suction source. With the feeding tube connected to the feed source, nutrients are supplied to the subject through the feeding tube, and with the feed source disconnected, the body of the unique Lopez valve connected to the feed tube by the male Luer-Lock extension and to the suction tube, the subject's stomach cavity is exposed to suction controlled by the conventional Lopez valve.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: April 18, 2023
    Inventor: Silviya Das
  • Patent number: 11622884
    Abstract: The present invention provides a cannulation device for administering an active agent containing composition to the suprachoroidal space or supraciliary space. The invention provides methods of treatment of an ocular disease or condition accordingly. The invention also provides compositions for use in a method of treatment of an ocular disease or condition for delivery into the suprachoroidal space or supraciliary space.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: April 11, 2023
    Assignee: Oxular Limited
    Inventors: Robert Steven Bley, Stanley R. Conston, Ronald Yamamoto
  • Patent number: 11596325
    Abstract: Systems and methods for measurement of end tidal carbon dioxide, including a device having a body and a tubular gas line. The body is adapted to be attached to a patient airway and has a first gas line securing portion which has an aperture through it and is adapted to secure the gas line to the body. The tubular gas line is secured in the aperture. The tubular gas line has a proximal portion extending from a proximal end of the aperture and has a proximal end which is adapted to be connected to an end tidal CO2 monitor. The tubular gas line also has a distal portion extending from a distal end of the aperture and having a distal end which provides an inlet for end tidal CO2 exhaled by a patient.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: March 7, 2023
    Inventors: Jeffrey J. Rockwell, Mark L. Berrier
  • Patent number: 11571236
    Abstract: An apparatus includes a body assembly, an acoustic waveguide, an ultrasonic blade, a liquid dispensing feature, and a control module. The liquid dispensing feature is positioned distally relative to the body assembly. The liquid dispensing feature is positioned adjacent to the ultrasonic blade. The liquid dispensing feature is configured to deliver a flow of cooling liquid to the ultrasonic blade. The control module is operable to regulate fluid flow through the liquid dispensing feature.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: February 7, 2023
    Assignee: Cilag GmbH International
    Inventors: David C. Yates, Benjamin M. Boyd, Benjamin D. Dickerson, Brian D. Black, Craig N. Faller, Kristen G. Denzinger, Paul F. Riestenberg, David M. Locke, Jacob S. Gee, Joseph Dennis, Ashvani K. Madan
  • Patent number: 11419490
    Abstract: A surgical system including an endoscopic navigation catheter, at least one laparoscopic access port, a laparoscopic tool, and an endoscopic tool. The endoscopic navigation catheter is configured for navigation of a luminal network to an area of interest. The at least one laparoscopic access port is placed adjacent to the area of interest. The laparoscopic tool is configured for insertion through the at least one laparoscopic access port, and the endoscopic tool is configured for insertion through the endoscopic navigation catheter. The laparoscopic tool and endoscopic tool enable a combined laparoscopic and endoscopic approach to the area of interest.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: August 23, 2022
    Assignee: COVIDIEN LP
    Inventor: William S. Krimsky
  • Patent number: 11344681
    Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: May 31, 2022
    Assignee: AMGEN INC.
    Inventors: Lawrence S. Ring, Dhairya Mehta, Stephanie Toy, Ferry Tamtoro, Alexander Stuart Cairns, Scott R. Gibson
  • Patent number: 11116885
    Abstract: Disclosed herein are systems and methods for providing reduced or negative pressure, and more particularly cyclical reduced pressure, to treat a wound. The system can include a wound dressing, a fluid collection container, a suction source, filters, and conduits. In addition, the system can include a control device and sensors. The sensors may be configured to monitor certain physiological conditions of a patient such as temperature, pressure, blood flow, blood oxygen saturation, pulse, cardiac cycle, and the like. Application of cyclical reduced pressure between two or more values below atmospheric pressure may be synchronized with the physiological conditions monitored by the sensors. Certain embodiments of the system utilize an air reservoir and one or more valves and pressure sensors or gauges to allow for rapid cycling of the level of reduced pressure within the wound dressing between two or more reduced pressure values.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: September 14, 2021
    Assignees: Smith & Nephew, Inc., Smith & Nephew PLC
    Inventors: Richard Scott Weston, Edward Yerbury Hartwell
  • Patent number: 10828423
    Abstract: A dispensing device for dispensing medication from a medication container. The dispensing device includes a housing, a drive member engageable with the medication container, at least one first ramp surface fixed relative to the housing, a driver movable within the housing to move the drive member for forcing medication from the medication container, the driver including at least one second ramp surface, and a plunger including at least one push module movable relative to the housing from a ready position to a plunged position.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: November 10, 2020
    Assignee: Eli Lilly and Company
    Inventor: Jared Alden Judson
  • Patent number: 10618062
    Abstract: A fluid discharge apparatus includes a storage chamber, a moving body, a drive mechanism, and a coupling member. The storage chamber includes a discharge port to discharge the fluid. The moving body includes a leading end portion facing the discharge port inside the storage chamber. The drive mechanism is positioned on the opposite side of the moving body to the discharge port, and performs an operation to reciprocate the moving body. The coupling member couples the moving body to the drive mechanism such that the moving body is attachable and detachable. The coupling member includes a biasing section to apply an elastic force in a direction to move the moving body toward the drive mechanism, and, while pressing the moving body against the coupling member, to support the moving body in a state in which the moving body is capable of elastic displacement in a direction toward the discharge port.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: April 14, 2020
    Assignee: Seiko Epson Corporation
    Inventors: Shinichi Nakamura, Takahiro Katakura, Keigo Sugai, Hirofumi Sakai, Junichi Sano
  • Patent number: 10268236
    Abstract: An electronic device may have a metal housing. The metal housing may have an upper housing in which a component such as a display is mounted and a lower housing in which a component such as a keyboard is mounted. Hinges may be used to mount the upper housing to the lower housing for rotation about a rotational axis. A slot-shaped opening may separate the upper and lower housing. Flexible printed circuits with ground traces may bisect the slot-shaped opening to form three electrically isolated slots each of which is aligned with a respective cavity antenna. The antennas may have antenna grounds formed from portions of the metal housing and other conductive structures. Resonating elements for the antennas may be supported by an elongated ventilation port structure along the rear edge of the lower housing.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: April 23, 2019
    Assignee: Apple Inc.
    Inventors: Jerzy S. Guterman, Joel D. Barrera, Kevin M. Robinson, Daniel D. Hershey
  • Patent number: 10072157
    Abstract: Methods and apparatuses are disclosed relating to the delivery of primer compounds in liquid form to substrates from a hand-held device. Apparatuses are disclosed that, in a single barrel device, store primer components, mix primer components to achieve an activated primer, and deliver the activated primer to a substrate surface.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: September 11, 2018
    Assignee: THE BOEING COMPANY
    Inventors: Warren D. Philbeck, Rodney J. Washington
  • Patent number: 9955940
    Abstract: An echogenic nerve block catheter and an echogenic catheter tip member include an echogenic tip member having a plurality of ridges on a first portion of the tip member and a retainer member is on a second portion of the tip member, and the second portion of the tip member is received within the lumen of the nerve block catheter.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: May 1, 2018
    Assignee: Avent, Inc.
    Inventors: Alfred C. Coats, Louis Lupin, Paul E. Bigeleisen
  • Patent number: 9623227
    Abstract: A tubing set suitable for use in co-operation with a machine for carrying out a hemodialysis treatment of a patient's blood includes a blood out-tube for supplying the blood from the patient to a filter, a blood in-tube for supplying the blood from the filter back to the patient, and a substitution tube connected to the blood in-tube or the blood out-tube suitable for providing a substitution fluid in the patient's blood. The substitution tube includes an insert for the infusion of drugs, with the insert being configured to cooperate with a vial. A method of delivering drugs includes use of the tubing set, including the substitution tube, the insert, and the vial.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: April 18, 2017
    Assignee: PRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Reinhold Rieter, Massimo Fini
  • Patent number: 9579151
    Abstract: A microwave ablation probe for providing microwave energy to tissue is disclosed. The probe includes a feedline having an inner conductor, a secondary inner conductor, and insulating spacer, and an outer conductor. The inner conductor is slidably disposed within the secondary inner conductor. The feedline also includes a radiating portion having an extruded portion of the inner conductor centrally disposed therein, wherein longitudinal movement of the inner conductor relative to the feedline tunes the radiating portion.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: February 28, 2017
    Assignee: COVIDIEN LP
    Inventors: Christopher T. Rusin, Joseph D. Brannan
  • Patent number: 9555225
    Abstract: The invention relates to an intraruminal sustained release capsule which is capable of delivering a sustained release dose of a first medicament to an animal, as well as either or both of a dump dose of a second medicament or mineral, and an exit dose of a third medicament or mineral. The capsule can have a dissolvable overcap molded from plasticized starch enabling a dump dose of medicament to be held between the overcap and one end of the capsule. A piston within the body of the capsule can be modified to enable it to accommodate an exit dose of medicament within its hollow interior which is aligned with an aperture at the end of the capsule which enables release of the medicaments to the rumen. After insertion of the capsule in the animal the overcap (if present) dissolves and separates from the capsule to release the dump dose of medicament. The sustained release medicament is then dispensed via the apertured end, followed by the release of the exit dose of medicament (if present).
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: January 31, 2017
    Assignee: MERIAL INC.
    Inventor: Robert William Lachlan Holmes
  • Patent number: 9550026
    Abstract: It is possible to feed an injection objective substance to a depth of a skin structure of an objective living body without using any injection needle. A syringe having no injection needle comprises an ignition device which includes an ignition charge containing a fuel component and an oxidizing agent component, a combustion chamber into which a combustion product produced by a reaction of the fuel component and the oxidizing agent component during combustion of the ignition charge is allowed to flow and which accommodates a gas generating agent that is combustible by the combustion product to generate a predetermined gas, and an enclosing unit which encloses the injection objective substance, wherein the injection objective substance enclosed in the enclosing unit is pressurized by a pressure in the combustion chamber in this construction.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: January 24, 2017
    Assignee: DAICEL CORPORATION
    Inventor: Shingo Oda
  • Patent number: 9468460
    Abstract: The present invention regards a guiding tool for neurosurgery. The guiding tool comprises subunits and a holder. The subunits are arranged in the holder so that holes for guiding a probe are created in the interface between said subunits, which allows easy release of the probe. The invention further regards a system for guiding neurosurgery probes.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: October 18, 2016
    Assignee: Medtronic Bakken Research Center B.V.
    Inventors: Hubert Cecile Francois Martens, Michel Gerardus Pardoel
  • Patent number: 9364286
    Abstract: Devices, systems and methods are disclosed for the ablation of tissue. A steerable ablation catheter can include one or more ablation elements at its distal end and one or more ablation elements fixedly attached to its shaft. The distal end of the ablation catheter can be deflected to assume a number of different deflection geometries in at least one direction along the shaft. One feature of the ablation catheter is that its shaft can comprise materials of differing durometers or stiffnesses attached together at a joint. Methods associated with use of the ablation catheter are also covered.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: June 14, 2016
    Assignee: Medtronic Ablation Frontiers LLC
    Inventors: Randell L. Werneth, Ricardo D. Roman, Christopher G. Kunis, Alexander J. Asconeguy, Sadaf Soleymani, Jeffrey Trinidad, Martin Chambers, Hakan Oral, Fred Morady, Jerald L. Cox, Guillermo W. Moratorio, Samuel Fu, J. Christopher Flaherty
  • Patent number: 9345857
    Abstract: The invention relates to an injection catheter for delivering a therapeutic agent into a substrate, comprising one or more lumens and a curved delivery element, said lumen serving as a guide for said curved delivery element outside of the substrate; said curved delivery element comprising openings on its distal tip, said distal tip comprising a distal zone and a proximal zone, said injection catheter being characterized in that the specific surface in said distal zone of said distal tip of said curved delivery element is higher than the specific surface in said proximal zone of said distal tip of said curved delivery element. The invention also relates to a process for delivering a therapeutic agent into a substrate.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: May 24, 2016
    Assignee: Cardio3 Biosciences
    Inventors: Jean-Pierre Latere Dwan'isa, Christian Homsy, Jozef Bartunek, Roland Gordon-Beresford
  • Patent number: 9278164
    Abstract: A negative pressure wound therapy system creates a negative pressure environment in the opening of a wound-dressing unit and a positive pressure environment in the collecting bag. Then a positive pressure detecting procedure is proceeded in the positive pressure environment and a negative pressure detecting procedure is proceeded in the negative pressure environment. The detecting results are sent to determine whether a micro pump is stopped.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: March 8, 2016
    Assignee: APEX MEDICAL CORP.
    Inventors: Nan-Kuang Yao, Jhy-Wen Wu, Luo-Hwa Miau, Jen-Chien Chien, Li-Ling Li
  • Patent number: 9237901
    Abstract: A liquid injection device includes an injection unit which injects a liquid, a liquid supply instrument which supplies the liquid to the injection unit, and a control unit which controls operation of the injection unit and the liquid supply instrument, wherein the injection unit includes a distal end portion where a nozzle for injecting the liquid is formed, and a body portion in which the distal end portion is removably loaded, at the distal end portion, a distal end-side memory is provided in which first startup data is written, and the control unit is a control unit which reads and writes the first startup data from and to the distal end-side memory in the distal end portion loaded in the body portion and manages use time of the distal end portion based on the first startup data that is read out.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 19, 2016
    Assignee: Seiko Epson Corporation
    Inventors: Tsunemori Asahi, Hirokazu Sekino
  • Patent number: 9238187
    Abstract: A filter device includes a main body portion having a cylinder shape, and the main body portion is inserted along a center axis of the pipe. One end portion of the main body portion structuring a filter device is blocked. At least one portion of a flange portion is provided between both end portions of the cylinder, and the flange portion divides a space inside the pipe in a liquid-tight state by elastically deforming and by being attached firmly to an inner surface of the pipe. A first passing portion of the liquid is provided in a cylinder side portion between the one end portion of the cylinder and the flange portion, and a second passing portion of the liquid is provided on a side close to the other end portion of the cylinder than the flange portion.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: January 19, 2016
    Assignee: Nifco Inc.
    Inventor: Shoh Kawaguchi
  • Patent number: 9168056
    Abstract: Fluid is pressurized and supplied to a fluid chamber with a fluid pressurizing and supplying unit. The pressurized fluid within the fluid chamber is ejected through an injection nozzle by reduction of the volume of the fluid chamber caused by applying a driving voltage to a volume varying unit. In applying the driving voltage to the volume varying unit, the effect imposed on fluid injection by pressure fluctuations of the fluid pressurized and supplied to the fluid chamber is compensated by changing the voltage waveform of the driving voltage. When the pressure of the supply flow amount is decreased to a pressure lower than a predetermined pressure, the time intervals of the driving waveform are corrected. The maneuverability of a fluid injection device does not deteriorate even when the pressure of the fluid pressurized and supplied to the fluid chamber fluctuates.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: October 27, 2015
    Assignee: Seiko Epson Corporation
    Inventors: Kazuaki Uchida, Hideki Kojima, Atsuya Hirabayashi
  • Patent number: 9107628
    Abstract: An intubation instrument for intubating a patient's trachea including an imager module having a base unit with a finger loop and a longitudinal member attached to the distal end of the base unit, as well as a blade having a handle that is hollow and mates with the outer surface of the longitudinal member forming a male-female connection, the distal end of the blade projecting laterally therefrom, the distal end of the blade being insertable into a human during intubation.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: August 18, 2015
    Assignee: KARL STORZ GMBH & CO. KG
    Inventors: Dieter Huels, Eugenia Fuhr, Ulrich Merz, Martin Renner, Fabian Zimmerli
  • Patent number: 9050445
    Abstract: The present invention relates generally to a tattoo needle stabilization device. More specifically, this disclosure relates to a device that is inserted through the sanitary cutout and engages the shaft of a tattoo needle near the point, biasing the point of the needle against the inside of the tip aperture and stabilizing the needle.
    Type: Grant
    Filed: January 28, 2012
    Date of Patent: June 9, 2015
    Inventors: David Klebs, Jonathan Castle
  • Patent number: 9039712
    Abstract: The present invention provides a medical device having an catheter body defining proximal and distal portions, and a guidewire lumen at least partially disposed within and movable within the catheter body. The medical device may include an expandable element defining a proximal end and a distal end, wherein the proximal end is coupled to the distal portion of the catheter body and the distal end is coupled to the guidewire lumen. In addition, an actuator element may be coupled to the guidewire lumen for longitudinal movement thereof, and a tensioning element may further be coupled to the guidewire lumen to bias the guidewire lumen and/or the expandable element towards a particular geometric configuration.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: May 26, 2015
    Assignee: Medtronic CryoCath LP
    Inventors: Marwan Abboud, Dan Wittenberger
  • Patent number: 9012714
    Abstract: A wound treatment device comprises a wound surface contacting plug and a cover for covering the wound surface and the plug, wherein said plug consists of a flat textile isolating material comprising at least one first surface layer, one second surface layer and one intermediate space arranged between said surface layers. At least the first surface layer is provided with a biocompatible surface and a structure which enables a liquid to pass and prevents a wound tissue from growing in said structure. The intermediate space is provided with isolating threads elastically holding the first surface layer and the second surface layer at a certain distance from each other.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: April 21, 2015
    Inventor: Wilhelm Fleischmann
  • Patent number: 9011414
    Abstract: One embodiment of the present invention relates to a minimally invasive implant-based ventral hernia repair system including a first and second elongated member in which the second elongated member extends through the internal channel of the first elongated member. A set of arm members are moveably coupled to the distal end of the first elongated member. A set of tension members extends lengthwise along the arm members and is rigidly coupled between the distal most segment of each arm member and the second elongated member. The degree of tension in the tension members corresponds to the configuration of the arm members with respect to the first elongated member. The proximal translation of the second elongated with respect to the first elongated member causes tension on the tension members, which thereby articulates the arm members into a radial extended configuration in which the arm members extend radially and substantially perpendicular to the first elongated member.
    Type: Grant
    Filed: December 26, 2013
    Date of Patent: April 21, 2015
    Inventor: Adam Judd Hansen
  • Patent number: 8998882
    Abstract: The present disclosure relates to a packaged urinary catheter. The catheter includes a conduit having a proximal end and a distal end. The distal end includes at least one aperture for receiving urine from the bladder. The catheter is contained within a sleeve having a length, a width, and a size configured to receive the catheter. According to one embodiment, the catheter and the sleeve may be arranged in a helical coil. The outer surface of the catheter may have a lubricious and/or an antimicrobial coating.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: April 7, 2015
    Assignee: C. R. Bard, Inc.
    Inventors: Tracey E. Knapp, Vasu Nishtala
  • Patent number: 8998848
    Abstract: Apparatus and methods are provided to access bone marrow at various target areas. Such apparatus may include an intraosseous device operable to penetrate bone at a selected target area and a depth limiter operable to control depth of penetration of the intraosseous device into bone and associated bone marrow. A manual driver and a guide may be included to optimize optimum insertion of the intraosseous device at a selected insertion site on a sternum.
    Type: Grant
    Filed: January 8, 2007
    Date of Patent: April 7, 2015
    Assignee: Vidacare LLC
    Inventors: Larry J. Miller, Robert W. Titkemeyer, David S. Bolleter, Ruben Trevino, Matthew T. Harmon, Christopher Kilcoin
  • Patent number: 8979818
    Abstract: An object of the invention is to provide a method and apparatus for the delivery of polynucleotide vaccines into mammalian skin cells to increase T cell response and to reduce pain and discomfort due to long electric waveform application and due to muscle contractions. The method for the delivery of polynucleotide vaccines into mammalian skin cells includes the steps of: (a.) administering a polynucleotide vaccine into the skin at an administration site, (b.) applying a needle electrode to the skin in the vicinity to the administration site, and (c.) applying a sequence of at least three single, operator-controlled, independently programmed, narrow interval electrical waveforms, which have pulse intervals that are less than 100 milliseconds, to deliver the polynucleotide vaccine into the skin cells by electroporation.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: March 17, 2015
    Assignee: Cellectis
    Inventors: Derin C. Walters, Alan D. King, Anna-Karin Roos, Robert J. Walters
  • Patent number: 8951221
    Abstract: The invention relates to a method and device for the treatment of glaucoma, though insertion of an implant into the lumen of the Schlemm's canal to realize proper drainage of the aqueous humor, which implant is brought into its position in the Schlemm's canal by means of a catheter having a distal and a proximate portion and provided with a number of pores through which a gaseous or fluid medium which comes from a pressure source can emerge during insertion of the catheter carrying the implant into the Schlemm's canal, and while the catheter is being inserted into the Schlemm's canal the gaseous or fluid medium is released under pressure thereby expanding the Schlemm's canal and the implant and upon releasing the implant at its determined location, the catheter can be withdrawn from the Schlemm's canal.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: February 10, 2015
    Assignee: Grieshaber Ophthalmic Research Foundation
    Inventors: Robert Christopher Stegmann, Matthias Christian Grieshaber, Hans Rudolf Grieshaber
  • Patent number: 8945038
    Abstract: A surgical technique and device wherein an indwelling tube is placed in the eye of a patient having glaucoma. The tube diverts aqueous humor from the anterior chamber to the suprachoroidal space from which it is removed by blood flowing in the choroidal and uveal tissues. This decreases the intraocular pressure.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: February 3, 2015
    Assignee: Transcend Medical, Inc.
    Inventor: Michael Yablonski
  • Patent number: 8945600
    Abstract: Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include administering at least one pharmaceutical agent onto a SEM graft in the skull base of the subject. Also provided are methods of treating a neurological disorder or pain in a subject that include forming a SEM graft in the skull base of the subject and administering at least one pharmaceutical agent onto the SEM graft in the skull base of the subject. Also provided are methods of forming a SEM graft in the skull base of a subject, compositions for administration onto a SEM graft in the skull base or into an endonasal reservoir or endonasal reservoir device in a subject, and devices for administering such compositions onto a SEM graft in the skull base of a subject.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: February 3, 2015
    Assignee: Massachusetts Eye & Ear Infirmary
    Inventor: Benjamin S. Bleier
  • Patent number: 8942781
    Abstract: The percutaneous probe, made in MRI-compatible materials, comprises: a body percutaneously inserted into the tissue of a patient's body organ (8) having a region (10) to be analyzed, treated and monitored during a single medical procedure; at least one information collection sensing device (30,33,34); treatment application transducers (30) 360° disposed to emit focused or defocused therapeutic ultra-sound waves. The computerized system comprises a parametrizable command device (50) adapted to simulate then command a generation of the therapeutic ultra-sound waves, and to monitor the treatment by thermal MRI images.
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: January 27, 2015
    Assignees: Universite Pierre et Marie Curie (Paris 6), Assistance Publique Hopitaux de Paris
    Inventors: Alexandre Carpentier, Julian Itzcovitz
  • Patent number: 8915879
    Abstract: Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods. One method of dispensing medicament from a cartridge includes pushing a plunger so as to controllably dispense out of a medicament reservoir within the cartridge in accordance with a stored delivery profile an amount of medicament of 0.1% or less of the total filled volume of the reservoir and with a single-dose precision of better than plus or minus 20%. The single-dose precision is obtained after a time-to-precision period of less than eight hours, which begins at the onset of the first plunger pushing for the cartridge, during which the plunger is being pushed in accordance with the stored delivery profile.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: December 23, 2014
    Assignee: perQflo, LLC
    Inventors: Roger E. Smith, James Causey, Scott R. Gibson
  • Patent number: 8911422
    Abstract: An object of the present invention is to efficiently inject a drug (physiologically active substance). Therefore, a micro-needle device 1 comprises a base plate 2 and a micro-needle 3 installed on the base plate 2. A coating agent containing the physiologically active substance is coated at least at a part of the micro-needle 3, and a coating range thereof is 100 to 230 ?m including the top of the micro-needle 3. A load due to the energy of 0.2 to 0.7 J/cm2 is applied to the micro-needle device 1 which is in contact with the skin.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: December 16, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Tetsuji Kuwahara, Seiji Tokumoto, Kazuya Machida
  • Patent number: 8870852
    Abstract: A medical device for providing direct port-like endoscopic access to the urinary bladder of a patient and a method of utilizing and inserting the medical device. The medical device can include a hollow tube with a main channel and a separate channel, a cap with an inflation port and a hollow flexible stem fluidly connecting the inflation port and the separate channel. A method can include inserting a needle above the pubic symphysis of a mammal, threading a guide wire through the needle, removing the needle and inserting the medical device. The method can optionally include determining measuring the depth between the skin surface of the patient's suprapubic region and urinary bladder.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: October 28, 2014
    Assignee: Tycast Technologies, LLC
    Inventors: Frank J. Tycast, James F. Tycast
  • Patent number: 8852258
    Abstract: A catheter assembly includes a catheter, including an inner member and a sheath, extending from a handle. The handle includes a housing, a braking assembly, a carriage and a carriage driver. The braking assembly comprises a braking element within the housing interior and a braking element rotator. The carriage comprises at least one carriage braking surface engaging the braking element. The carriage driver, such as a spring, biases the carriage towards the proximal end of the handle. The inner member has a proximal end secured to the housing. The sheath has a proximal end secured to the carriage. Rotating the braking element causes the carriage to move proximally as the carriage braking surface slides along the braking element. This causes the sheath to move proximally relative to the inner member.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: October 7, 2014
    Assignee: NovoStent Corporation
    Inventors: Alexander Arthur Lubinski, Eric W. Leopold, Gerald Ray Martin
  • Patent number: 8852157
    Abstract: Disposable items made from bioplastic resins include a biodegradable resin; and a plasticizer; wherein the resin and plasticizer are intermixed to provide a generally homogenous bioplastic that is formed to provide the device. A disposable device includes a multidose syringe, a specimen tube, a scalpel, a lancet, a sharps container, or a suction canister. A method of disposing of an item includes providing an item made from a biodegradable resin and a plasticizer that are intermixed to provide a generally homogenous bioplastic; sterilizing the item utilizing radiation or ethylene oxide gas; shredding the item; and composting the item into a compost end product, thereby disposing of the item.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: October 7, 2014
    Assignee: Innovative Bottles, LLC
    Inventor: Shantu Patel
  • Patent number: 8834416
    Abstract: Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: September 16, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Ronald A. Sahatjian, Arthur Madenjian, William R. Little
  • Patent number: 8827969
    Abstract: A medical waste fluid collection and disposal system includes a medical waste fluid collection cart including first and second fluid collection canisters. A valve assembly selectively communicates with the canisters and a valve drive system controls the valve assembly. A liquid level sensor is positioned within each of the canisters. A cart processor communicates with the liquid level sensors and the valve drive system. A cart drain line communicates with the valve assembly and a receptacle, a cart flushing line communicates with the valve assembly and the receptacle and a cart data line and a cart power line communicate with the cart processor and the cart receptacle. A station includes a drain pump that communicates with a drainage system and a station drain line, a flushing pump that communicates with a source of washing liquid and a station flushing line and a station processor in communication with the drain and flushing pumps. A station data line communicates with the station processor.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: September 9, 2014
    Assignee: Dornoch Medical Systems, Inc.
    Inventors: Anthony Martini, Lawrence Guerra
  • Patent number: 8821472
    Abstract: The present invention provides an apparatus comprising a housing and a flexible reservoir adapted to contain a fluid and having a septum member formed from a needle-penetratable self-sealing material. The flexible reservoir is arranged within the housing in combination with mounting means arranged within or formed by the housing, wherein the mounting means engages the septum member to thereby mount the flexible reservoir relative to the housing. In this way a secure fixation between the reservoir and the housing is provided without having to interfere with the general flexibility of the reservoir, e.g. substantially the entire flexible reservoir apart from the outlet/mounting means may be arranged free to move relative to the housing, this allowing the reservoir to be emptied to a high degree.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: September 2, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Philip Albert Sparholt, Erik Winkel Ethelfeld, Steffan Hansen, Bjorn G. Larsen, Claus S. Moeller
  • Patent number: RE45571
    Abstract: A relatively inexpensive cannula is sized by including indica on a cannulated dilator that is used to measure the depth of a body cavity, and in one embodiment with the use of a cuttable fixture inserted into an initially enlarged dilator retractor made from a cuttable material the excess of the dilator retractor is snipped by a commercial cutter. A tool engaging the end of the cannulated dilator provides leverage on the cannulated dilator for rotation as it is forced into the body cavity, a pusher tool provides leverage on the dilator retractor for inserting the dilator retractor into the body cavity. A clamp that fits the top of the dilator retractor serves to support the dilator retractor through an arm to a rigid structure. In an alternate embodiment one of a series of sized dilator retractors are selected commensurate with the measurement attained by the scaled cannulated dilator.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: June 23, 2015
    Assignee: DePuy Synthes Products, Inc.
    Inventor: Robert E. Simonson
  • Patent number: RE46978
    Abstract: A relatively inexpensive cannula is sized by including indica on a cannulated dilator that is used to measure the depth of a body cavity, and in one embodiment with the use of a cuttable fixture inserted into an initially enlarged dilator retractor made from a cuttable material the excess of the dilator retractor is snipped by a commercial cutter. A tool engaging the end of the cannulated dilator provides leverage on the cannulated dilator for rotation as it is forced into the body cavity, a pusher tool provides leverage on the dilator retractor for inserting the dilator retractor into the body cavity. A clamp that fits the top of the dilator retractor serves to support the dilator retractor through an arm to a rigid structure. In an alternate embodiment one of a series of sized dilator retractors are selected commensurate with the measurement attained by the scaled cannulated dilator.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: August 7, 2018
    Assignee: DePuy Synthes Products, Inc.
    Inventor: Robert E. Simonson