Means For Metering Material Flow To Or From Body Patents (Class 604/186)
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Patent number: 8002753Abstract: An apparatus includes a medicament container and an actuator assembly coupled to a proximal end portion of the medicament container. A distal end portion of the medicament container is configured to be coupled to a needle. A piston is movably disposed within the medicament container such that the medicament container is divided into a first internal portion and a second internal portion, the first internal portion containing a medicament. The actuator assembly has a pressurized fluid container, a regulator and a bias member. The pressurized fluid container is configured to move relative to the medicament container between a first position and a second position. The regulator is configured to fluidically couple the pressurized fluid container and the second internal portion of the medicament container when the pressurized fluid container is in the second position. The bias member is configured to bias the pressurized fluid container in the first position.Type: GrantFiled: December 22, 2008Date of Patent: August 23, 2011Assignee: Nordson CorporationInventors: John F. Krumme, Leslie A. Field
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Publication number: 20110178468Abstract: A medicinal fluid injector having branch lines to inject a ringer solution together with a treatment solution is provided. If the vein of the patient is clogged, the treatment solution is not injected into the patient, but flows back into the ringer solution, which is injected into the patient through a free fall scheme. If the vein is open, the medicinal fluid is excessively injected at a time, causing fatal accident to the patient. To solve this problem, a check valve is installed in an injection tube to prevent the medicinal fluid or the blood from flowing back into the ringer solution even if pressure difference occurs in the medicinal fluid injector. If the medicinal fluid stagnates, an alarm is generated to notify medical staffs of the emergency, so that medicinal fluid injector is safely used.Type: ApplicationFiled: November 9, 2010Publication date: July 21, 2011Applicant: ACE MEDICAL CO., LTD.Inventor: Jong-Woo LEE
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Patent number: 7951113Abstract: A device for administering a fluid product including a housing, a conveying device for the product, a coupling element provided for the drive of the conveying device and which can be rotated about a rotational axis, a first blocking element connected in a rotationally secure manner to the coupling element, a second blocking element detachably engageable with the first blocking element thereby preventing a rotational movement thereof in the drive direction and enabling said rotational movement to take place in the counter dosing direction, a torsion spring connected to the coupling element such that it is stressed by the rotational movement when the blocking elements are engaged in a blocked position and drives the coupling element in a rotary manner after the blocking position is released, and a release element coupled to at least one of the blocking elements such that a release movement of the release element displaces at least one of the blocking elements from the blocked position, the release element alsoType: GrantFiled: June 27, 2007Date of Patent: May 31, 2011Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer, Edgar Hommann
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Patent number: 7914499Abstract: A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.Type: GrantFiled: March 28, 2007Date of Patent: March 29, 2011Assignee: Valeritas, Inc.Inventors: Robert Gonnelli, Steven F. Levesque, Ronald V. Nardi
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Patent number: 7744580Abstract: A device and a procedure for the extemporaneous preparation of an individual quantity of sterile treatment fluid that may be compressible, in particular a treatment gas, the device comprising a rigid cartridge (3) with an outlet valve, an administration syringe (4) and a filtration-type connection/sterilization device (5, 6). The cartridge (3) simply contains an individual quantity of treatment fluid under pressure, and the cylinder of the syringe (4) is adapted to contain this individual quantity.Type: GrantFiled: February 5, 2004Date of Patent: June 29, 2010Assignee: ArcadophtaInventor: Gerard Reboul
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Patent number: 7678085Abstract: An injection device for injecting selectable amounts of a substance includes an activating mechanism including an axially moveable operating button which can rotated in a resting position only, a tubular drive element non-rotatably connected to the operating button, an axially fixed and non-rotatable guiding element, and an axially moveable driven member held non-rotatably in the device. A rotational grid is operationally between rotatable and non-rotatable components of the injection device such that the operating button can be moved two rotational directions when in the resting position whereby a selected amount of the substance to be injected can be selectively varied. For example, a dosage inadvertently selected too large by rotating the operating button too far in one direction can, in accordance with the present invention, be reduced by rotating the operating button in the opposite direction.Type: GrantFiled: February 11, 2005Date of Patent: March 16, 2010Assignee: TecPharma Licensing AGInventor: Roney Graf
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Patent number: 7678080Abstract: An intravenous catheter introducing device includes a needle hub slidably inserted into a barrel and holding a needle cannula, a biasing member disposed to bias the needle hub to a rear position so as to retract the needle cannula in the barrel, and an easy release unit including an engaging wall segment which is attached to an outer surface of the barrel, two flexible squeezed wall segments which extend from the engaging wall segment and which is squeezable so as to move two latch members to steer clear of a retained end of the needle hub through an access hole in the barrel, thereby permitting the biasing member to bias the needle hub towards the rear position.Type: GrantFiled: October 15, 2007Date of Patent: March 16, 2010Inventors: Ming-Jeng Shue, Deborah Huang, Phillip Shue
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Patent number: 7511480Abstract: A device for administering a fluid product includes a measuring assembly for measuring a position between spaced apart elements of the apparatus that can be moved relative to each other. The measuring assembly includes at least one magneto-resistive sensor that is fixed to a first element, such as a casing, and is arranged opposite at least a second element, such as a sleeve, which can be moved relative to the first element. A magnetic device co-operates with the at least one sensor and is formed by a permanent magnet on the first element and a magnetized second element including a magnetic surface profile or including of a number of alternately arranged, different magnetic pole areas.Type: GrantFiled: January 6, 2006Date of Patent: March 31, 2009Assignee: TecPharma Licensing AGInventor: Beat Steffen
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Patent number: 7470259Abstract: A syringe is provided for limiting the dosage of medication delivered to a patient to a pre-determined amount. The syringe assembly includes an injector assembly and vial of medication. The injector assembly has an adjustable dosage control which rides in a track on the injector assembly for limiting vial movement. Once an appropriate dosage is selected using the dosage control, the vial is engaged with the injector assembly. As the vial is pressured into the injector assembly medication is forced through the needle. Once the vial reaches the dosage control, vial movement is obstructed and dosage effectively limited.Type: GrantFiled: March 24, 2006Date of Patent: December 30, 2008Inventor: John D. Hoyle, Jr.
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Patent number: 7320437Abstract: A liquid dispenser (100) primarily for use in dispensing liquid drench to animals. The dispenser (100) is electronic in operation and has the ability to control the speed of its pump (5) according to environmental conditions including the viscosity of the liquid being dispensed.Type: GrantFiled: February 26, 2002Date of Patent: January 22, 2008Assignee: Instrument Supplies LimitedInventors: Garth Anderson, Shaun Plant, Cornelis Klein
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Patent number: 7168597Abstract: A metering valve that includes a valve body defining a metering chamber having an inlet valve adapted to be reversibly actuable from an open position to a closed position located at the inlet, and an outlet valve adapted to be reversibly actuable from a dispensing to a non-dispensing position located at the outlet, where the outlet valve includes an outlet valve seat adapted to be in biasable contact with an outlet valve poppet is described. Aerosol containers and inhalation devices that include such metering valves are also described, as are methods of using such inhalation devices.Type: GrantFiled: February 23, 2000Date of Patent: January 30, 2007Assignee: Smithkline Beecham CorporationInventors: Anthony Patrick Jones, Gregor John McLennan Anderson, Paul Kenneth Rand
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Patent number: 7056307Abstract: The invention concerns a syringe for administering medication to an animal. The syringe includes a handle that may be manually actuated to dispense medication to the animal. The syringe also includes a valve that controls the flow of medication both into and out of the syringe. A sensor device on the syringe monitors when the medication has been administered in order to inform any attached pump that the syringe may be refilled. An LED informs the user when the syringe has been filled with medication and is ready for the administration of medication to the animal.Type: GrantFiled: June 2, 2003Date of Patent: June 6, 2006Inventors: James E. Smith, Bobby J. Myers, D. Steve Williams
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Patent number: 6972006Abstract: A syringe device incorporating ridges that cause resistive changes to the movement of the syringe gasket or plunger, thereby providing user feedback as to the position and speed of plunger movement. Such user feedback may be useful in stressful situations, under poor lighting conditions or in other unfavorable circumstances. Additionally, in certain embodiments these ridges may aid in accurate dispension or allow the syringe to derive additional functionality, such as performing as a vacuum source. Ridges can be protrusions such as tabs, bubbles or continuous rings for single or repeated use or these ridges may be formed as indentations. Ridges may be formed in patterns, in various sizes and shapes or these ridges may be mixed and matched as required or desired. Ridges may also be formed from a soluble material and the resistive change may itself provide indication that the material has been substantially dissolved and dispensed.Type: GrantFiled: September 18, 2002Date of Patent: December 6, 2005Assignee: G6 Science Corp.Inventor: Gary William Ferguson
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Patent number: 6973374Abstract: A control device and a drug delivery system containing such a control device are disclosed for delivery to a patient of a drug or a placebo (or ineffective dose of the drug) according to a partial reinforcement schedule, whereby the placebo (or ineffective dose of the drug) is delivered in whole or in part during one or more delivery events. Methods of modulating the drug/placebo delivery to a patient are also provided, whereby the delivery event is initiated either according to a patient-initiated signaling event (i.e., a self-medication mode) or an automated signaling event (i.e., automated mode).Type: GrantFiled: December 19, 2001Date of Patent: December 6, 2005Assignee: University of RochesterInventor: Robert Ader
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Patent number: 6802824Abstract: A catheter handpiece apparatus and method for delivering a desired dose with minimal potential for contamination of the injected substance and rapid, accurate delivery of the desired dose. In one embodiment, a carriage assembly affixed to an inner lumen is slidably located within a handpiece housing equipped with an outer lumen. The carriage assembly receives a dose carpule. An actuator knob cocks the carriage assembly and a spring-powered actuator mechanism. After the catheter is maneuvered to a desired injection site and a desired dose is set, depressing a first trigger causes the inner lumen tip to extend beyond the outer lumen into the injection site. Depressing a second trigger causes the actuator mechanism to push the desired dose from the dose carpule through the inner lumen into the injection site. A second embodiment provides a catheter handpiece with a carriage assembly cocking lever and an operator-powered dose delivery mechanism.Type: GrantFiled: June 17, 2002Date of Patent: October 12, 2004Assignee: SciMed Life Systems, Inc.Inventors: Timothy J. Mickley, Bruce Arthur Christie, Douglas F. Walker, Jeremy L. Connell
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Patent number: 6796964Abstract: An electrically powered, plunger-free, valve-free adjustable veterinary delivery system for the administration of veterinary pharmaceuticals or vaccines to a variety of poultry or livestock. The delivery system includes a rechargeable battery positioned to power an electric motor which is used to actuate a peristaltic pump that propels pre-determined quantity of fluid medicament through the system for delivery. The system teaches adjustable dosage control of the fluid medicament by means of an electronic control unit which uses photo-optic sensor to calibrate dosage.Type: GrantFiled: August 8, 2001Date of Patent: September 28, 2004Assignee: Eidson Associates, INCInventors: Wilbur L. Eidson, Jon Mathisrud
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Patent number: 6782886Abstract: An apparatus to make a certain volume of liquid available for atomization comprises a container adapted to hold a liquid, and a piston pump. The piston pump comprises a piston member and a valve body, with the piston member being slidable within the valve body. Further, the valve body functions with the piston member to define a metering chamber. In this way, the metering chamber is adapted to be filled with liquid from the container when the piston member is moved to a filling position, and the piston pump is adapted to dispense a known volume of the liquid from the metering chamber when the piston member is moved to a dispensing position.Type: GrantFiled: March 20, 2001Date of Patent: August 31, 2004Assignee: Aerogen, Inc.Inventors: Sharad Narayan, Yehuda Ivri, Cheng H. Wu, Miro S. Cater
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Patent number: 6770056Abstract: A device for dispensing a measured dose of liquid from an attached container which container has an elongate casing defining a dispensing cylinder, one end of the casing being adapted for mounting on the container. A plurality of dose indications are provided on the external surface of the casing so that a dose may be pre-selected by moving a dose setting collar along the casing. The collar has a stop engageable with a selected one of a multiplicity of recesses on the casing to secure the collar at the required position. A plunger having a piston co-operating with a cylinder defined by the casing is movable to lift the piston from said one end of the casing until the piston abuts the dose setting collar so charging the dispenser. Depression of the plunger to move the piston back to said one end dispenses the selected dose from an outlet port.Type: GrantFiled: August 22, 2002Date of Patent: August 3, 2004Assignee: Novartis AGInventors: Phil T. Price, Stephanie Bley, Bernard Sams
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Patent number: 6726661Abstract: Described is an electronic injection device wherein an electronic circuit is designed to work in two alternative modes: an air shot mode and a dose injection mode. When working in the air shot mode a small predetermined air shot dose is pressed out from the ampule when the injection button is actuated. When working in the injection mode, a dose set by operation of the dose setting means is injected by operation of the injection button. The electronic injection device is normally working in the air shot mode but shifts to work in the dose injection mode when it receives a signal indicating that the dose setting means has been operated. The circuit returns to its air shot mode when receiving a signal indicating that the set dose has been injected. This signal can originate either from a switch indicating that the protection cap is mounted or from a switch indicating that the injection button has been pressed.Type: GrantFiled: December 10, 2002Date of Patent: April 27, 2004Assignee: Novo Nordisk A/SInventors: Jens Munk, Denmark Denmark Aasmul, Henrik Ljunggreen, Lars Hofmann Christensen
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Patent number: 6641566Abstract: A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing, and a dose setting mechanism for controlling the movement of the shaft with respect to a fluid-containing cartridge removably positioned within or mounted to the housing. The flexible shaft, according to exemplary embodiments, includes a plunger and a flexible cable connected to the dose setting mechanism. The plunger and dose setting mechanism are connected together by the flexible shaft. The dose setting mechanism, in one aspect of the invention, includes a screw, a locking mechanism, and a nut assembly connected to the flexible shaft. The dose setting mechanism is used to set the dosage and prime the catheter. The plunger retracts into a recess to permit a new cartridge to be installed quickly.Type: GrantFiled: June 24, 2002Date of Patent: November 4, 2003Assignee: Sterling Medivations, Inc.Inventors: Joel Douglas, John Ramirez, Robert Hugo
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Patent number: 6605066Abstract: A device for the formation and delivery of a mixture, notably a surgical adhesive, consisting of a receptacle adapted for easy handling by the surgeon, and including the means of receiving two syringe barrels containing the constituents of the mixture, the means of simultaneously expelling the contents, the means of maintaining the contents of syringe containing the first constituent, at a predetermined temperature setting which is higher than body temperature, and a mixer simultaneously receiving the contents of the two syringes, and the mixer also being used for cooling.Type: GrantFiled: August 29, 2000Date of Patent: August 12, 2003Assignee: Imedex BiomateriauxInventors: Philippe Gravagna, Jean-Louis Tayot
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Patent number: 6582404Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.Type: GrantFiled: September 6, 2000Date of Patent: June 24, 2003Assignee: NNA/SInventors: Peter Christian Klitgaard, Steffen Hansen, Bo Radmer, Claus Schmidt Møller
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Patent number: 6579263Abstract: A contrast fluid delivery method and system includes a multiple-reuse filling section for attachment by conduit to a contrast fluid supply container, and a delivery section that is removably attached to the filling section for delivering contrast fluid held in the filling section to a patient. The filling section includes a main body having a fluid chamber, a contrast fluid filling inlet with a gravity-operated valve, an opening for connecting an operable power syringe, and a contrast fluid outlet fed through a spring-loaded one-way check valve. The delivery section includes a first delivery conduit connected between the contrast fluid outlet of the main body and the fluid inlet of an inline aspirator syringe, and a second delivery conduit connected at one end to a fluid outlet of the aspirator syringe and at the other to a catheter for delivering the contrast fluid to a patient.Type: GrantFiled: January 11, 2002Date of Patent: June 17, 2003Inventor: Milton Chernack
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Patent number: 6565538Abstract: An orientationally adjustable marking syringe provides automatic loading of medicine from a medicine source to the syringe. Actuation of the handles of the syringe simultaneously discharges or injects the contents of the syringe and a marking substance such as ink contained in an ink dispenser integrally attached to the marking syringe by a pivoting ink carriage. The pivoting ink carriage can be pivoted about the syringe to better accommodate the ergonomic desires of the user and the objectives of the injection.Type: GrantFiled: June 2, 2001Date of Patent: May 20, 2003Assignee: Prima Tech USAInventors: Kimberly Quinn, Thomas Hogan
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Publication number: 20030083626Abstract: Described is an electronic injection device wherein an electronic circuit is designed to work in two alternative modes: an air shot mode and a dose injection mode. When working in the air shot mode a small predetermined air shot dose is pressed out from the ampule when the injection button is actuated. When working in the injection mode, a dose set by operation of the dose setting means is injected by operation of the injection button. The electronic injection device is normally working in the air shot mode but shifts to work in the dose injection mode when it receives a signal indicating that the dose setting means has been operated. The circuit returns to its air shot mode when receiving a signal indicating that the set dose has been injected. This signal can originate either from a switch indicating that the protection cap is mounted or from a switch indicating that the injection button has been pressed.Type: ApplicationFiled: December 10, 2002Publication date: May 1, 2003Inventors: Jens Munk, Soren Aasmul, Henrik Ljunggreen, Lars Hofmann Christensen
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Patent number: 6530906Abstract: A safety syringe comprises a barrel having a grip lug with two fitting holes and two retaining holes communicating with each other; an elastic lashing member capable of retracting elastically and inwards, and having two locating pillars which are provided with an arresting head being retained in the retaining holes of the barrel, two slide confining portions being disposed at each side; a plunger having two slide pieces; a needle holder being caught and pulled by the plunger, and fitting a needle set. In use, the slide pieces of the plunger are confined by the slide confining portion of the elastic lashing member such that the plunger can not be turned. The plunger arrives at the bottom in the wake of injection such that the plunger is not confined by the elastic lashing member, and that the plunger can be thus turned to actuate the needle holder and drawn into the interior of the barrel by the plunger.Type: GrantFiled: June 25, 2001Date of Patent: March 11, 2003Assignee: Taiject Medical Device Co., Ltd.Inventor: Chien-Kung Hu
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Patent number: 6514230Abstract: Described is an electronic injection device wherein an electronic circuit is designed to work in two alternative modes: an air shot mode and a dose injection mode. When working in the air shot mode a small predetermined air shot dose is pressed out from the ampule when the injection button is actuated. When working in the injection mode, a dose set by operation of the dose setting means is injected by operation of the injection button. The electronic injection device is normally working in the air shot mode but shifts to work in the dose injection mode when it receives a signal indicating that the dose setting means has been operated. The circuit returns to its air shot mode when receiving a signal indicating that the set dose has been injected. This signal can originate either from a switch indicating that the protection cap is mounted or from a switch indicating that the injection button has been pressed.Type: GrantFiled: September 28, 2000Date of Patent: February 4, 2003Assignee: Novo Nordisk A/SInventors: Jens Munk, Denmark Denmark Aasmul, Henrik Ljunggreen, Lars Hofmann Christensen
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Publication number: 20030005926Abstract: There is provided a medicament dispenser comprising a body, a medicament container and reset means for resetting a mechanical mechanism after actuation thereof, wherein the reset means comprises a reset coupling. The coupling is reversibly deformable in response to the application of non-mechanical energy thereto. The non-mechanical energy may comprise heat energy, electrical current energy, electrical field energy or magnetic field energy.Type: ApplicationFiled: June 10, 2002Publication date: January 9, 2003Inventors: Anthony Patrick Jones, Paul Kenneth Rand, Duncan Robertson
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Patent number: 6482186Abstract: A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing, and a dose setting mechanism for controlling the movement of the shaft with respect to a fluid-containing cartridge removably positioned within or mounted to the housing. The flexible shaft, according to exemplary embodiments, includes a plunger and a flexible cable connected to the dose setting mechanism. The plunger and dose setting mechanism are connected together by the flexible shaft. The dose setting mechanism, in one aspect of the invention, includes a screw, a locking mechanism, and a nut assembly connected to the flexible shaft. The dose setting mechanism is used to set the dosage and prime the catheter. The plunger retracts into a recess to permit a new cartridge to be installed quickly.Type: GrantFiled: September 29, 2000Date of Patent: November 19, 2002Assignee: Sterling Medivations, Inc.Inventors: Joel Douglas, John Ramirez, Robert Hugo
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Publication number: 20020156458Abstract: An intraurethral device for use in a female urinary tract is provided. The intraurethral device comprises a urethral element that contains a chemical compound capable of treating or detecting the presence or absence of a disorder or disease. In one embodiment, the intraurethral device also contains outer and inner insertion elements that are in operative communication with the urethral element to facilitate the insertion of the urethral element into the urethra without substantially contaminating the chemical compound prior to insertion.Type: ApplicationFiled: March 12, 2002Publication date: October 24, 2002Applicant: Clemson UniversityInventors: Robert A. Latour, Brent G. Carman
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Patent number: 6416498Abstract: This device comprises: a syringe body equipped with an access which may be connected in succession to a filling member, such as a needle, and to an infusion line fitted with a non-return valve to allow liquid to pass from the syringe into the line; a housing mounted so that it can slide in leaktight fashion inside the body so as to vary the volume of a chamber which it delimits with the body of the syringe; an element which, forming a piston, mounted on the housing and in contact with the chamber, is able, according to its position, to create a raised pressure or reduced pressure in the chamber; means for moving the piston-forming element back and forth.Type: GrantFiled: January 5, 2000Date of Patent: July 9, 2002Assignee: Laboratoire AguettantInventor: Pierre Frezza
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Patent number: 6413241Abstract: The present invention provides a syringe comprising a syringe barrel having a plurality of non-volumetric measuring indicia thereon. The present invention also provides a container comprising: at least one chamber; a plurality of non-volumetric measuring indicia on the at least one chamber; and an opening control device in the at least one chamber for allowing liquid contained in the at least one chamber to be withdrawn from the at least one chamber.Type: GrantFiled: March 31, 2000Date of Patent: July 2, 2002Assignee: Science & Technology Corporation @UNMInventor: Samuel Slishman
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Patent number: 6406460Abstract: A syringe has a sensor for sensing physical contact between a syringe needle and the syringe. As the sensor detects that a syringe needle has just been installed into the syringe, a counter is set to “zero”, indicating the number of injections given with the installed needle. The counter automatically and cumulatively counts each injection given to the animal during a period of continuous physical contact between the syringe and the syringe needle. When the number of cumulatively counted injections equals a predetermined maximum number of injections, a syringe needle change warning mechanism delivers a needle change warning to the operator of the syringe.Type: GrantFiled: July 21, 2000Date of Patent: June 18, 2002Assignee: Agecom, Inc.Inventor: Thomas Hogan
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Publication number: 20020022802Abstract: A wrap spring clutch syringe ram pushes one or more syringes precisely, rapidly, reproducibly, and reliably, with virtually instantaneous starting and stopping, and with constant motion at a defined velocity during the intervening push. The wrap spring clutch syringe ram includes an electric motor, a computer, a flywheel, a wrap spring clutch, a precision lead screw, a slide platform, and syringe reservoirs, a mixing chamber, and a reaction incubation tube. The electric motor drives a flywheel and the wrap spring clutch couples the precision lead screw to the flywheel when a computer enables a solenoid of the wrap spring clutch. The precision lead screw drives a precision slide which causes syringes to supply a portion of solution into the mixing chamber and the incubation tube. The wrap spring clutch syringe ram is designed to enable the quantitative study of solution phase chemical and biochemical reactions, particularly those reactions that occur on the subsecond time scale.Type: ApplicationFiled: June 13, 2001Publication date: February 21, 2002Inventor: Frank B. Simpson
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Patent number: 6348043Abstract: A multi-dose infusion pump employs a piston sliding within the internal chamber of a pump housing to dispense liquid from a port. The peripheral surface of the piston has a sequence of steps in a radial pattern spaced at intervals along the longitudinal axis of the chamber. A cap is rotatably mounted to the pump housing and includes a stop that limits forward movement of the piston by engaging a selected one of the steps on the piston at each rotational position of the cap. This causes a series of predetermined quantities of liquid to be dispensed as the cap is rotated to align the stop with each step in sequence. A spring between the cap and piston urges the piston forward in the chamber to dispense liquid from the port.Type: GrantFiled: June 21, 2000Date of Patent: February 19, 2002Assignee: McKinley Medical, LLLPInventors: Jeffrey A. Hagen, David W. Skinkle
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Publication number: 20010031948Abstract: A delivery device applies a biocompatible and biodegradable barrier material to a tissue region, e.g., to seal a vascular puncture site. The material comprises two liquid components, which are pre-packaged in individual dispensers. Upon mixing, the liquid components cross-link to create a barrier matrix. A holder attaches to the delivery device. The holder mutually supports the first and second dispensers while the protein solution and polymer solution are conveyed from the dispensers into a fluid delivery channel. The protein and polymer solutions mix as a result of flow through the channel.Type: ApplicationFiled: February 28, 2001Publication date: October 18, 2001Applicant: NeoMend, Inc.Inventors: Gregory M. Cruise, Olexander Hnojewyj
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Patent number: 6277099Abstract: A medication delivery pen includes a housing having an actuator disposed in the proximal end of the housing for setting and administering a dosage of medication, a medication-containing cartridge assembly having a cartridge with a pierceably sealed distal end, an open proximal end removably attachable to the distal end of the housing, and a piston in sliding, fluid tight engagement within the cartridge. A drive mechanism is coupled between the actuator and the cartridge to exert an axial force on the piston to inject the set dosage of medication. The actuator triggers the drive mechanism to administer the injection of medication held in the cartridge and a processor is coupled to the actuator to determine a value equal to the dosage set by the actuator.Type: GrantFiled: August 6, 1999Date of Patent: August 21, 2001Assignee: Becton, Dickinson and CompanyInventors: Robert J. Strowe, John E. Burbank, III, Jay D. Packman, Robert C. Uschold, Antonio A. Bendek
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Patent number: 6224572Abstract: A fluid delivery device for delivering fluid from a fluid reservoir to a patient. The device includes an inlet channel in communication with a fluid reservoir and a dosing chamber, and an outlet channel disposed in communication with the dosing chamber. A reciprocating dosing actuator is moveable in a reciprocating motion between first and second positions for alternately (i) transporting a dose of fluid conveyed by the inlet channel into the intermediate dosing chamber, and (ii) ejecting the dose from the dosing chamber through the outlet channel to the patient, respectively.Type: GrantFiled: May 4, 1995Date of Patent: May 1, 2001Assignee: Sarcos L.C.Inventors: Stephen C. Jacobsen, Clark C. Davis
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Patent number: 6213982Abstract: A medicament-dispensing system includes a cartridge for housing and actuating an accordion-like vial-dispenser for dispensing a calibrated amount of medicament by means of a single actuation motion which sequentially loads the vial-dispenser and dispenses the loaded medicament. The vial-dispenser has a front bellows portion, a rear bellows portion, an internal piston mechanism, a medicament storage chamber and a dosage cavity. The cartridge has a trigger mechanism which acts in concert with a notched lever and a wedge-shaped arm internally located in the cartridge to sequentially load the dosage cavity with medicament and discharge it. Depression of the trigger mechanism simultaneously extends, by means of the notched lever, the front bellows portion and compresses the rear bellows portion to load the dosage cavity with medicament.Type: GrantFiled: January 6, 2000Date of Patent: April 10, 2001Inventor: Daniel Py
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Patent number: 6159183Abstract: A medical fluid injector includes: an air detection system for detecting air in the neck of the syringe; a hand-operated control lever for controlling movement of the injector ram; magnetic conductors for delivering magnetic fields from a power head face plate to an internal circuit board to permit detection of different face plates; a tilt sensor detecting the tilt angle of the power head to control the speed of motion brought about by the hand-operated control lever and to control an invertible display; and a monitor microcontroller for monitoring the behavior of the central processing unit to detect and react to error conditions.Type: GrantFiled: November 10, 1999Date of Patent: December 12, 2000Assignee: Liebel Flarsheim CompanyInventors: Charles S. Neer, John N. Minnich
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Patent number: 6120481Abstract: This invention relates to a medical device having a plastic cylinder that is uniquely decorated. More particularly, this invention relates to an improved scale on a plastic syringe containing protruding volume measuring scale marks and indicia. These protrusions provide tactile sensation of the scale and slip-resistant holding of the syringe barrel. Both the plastic syringe barrel and scale can be formed separately, and then attached to each other. Methods of apply the scale in this manner include overmolding, and heat welding. The plastic syringe and improved scale can also be formed simultaneously using co-injection molding methods. Advantages of forming a scale on the plastic syringe using any of the techniques described above includes eliminating secondary operations such as printing, and permanently and accurately positioning the scale. Different thermoplastic and elastomeric materials and colors can also be used to form the scale. Another advantage is that the scale can be formed to 360.degree.Type: GrantFiled: December 21, 1998Date of Patent: September 19, 2000Assignee: Becton, Dickinson and CompanyInventors: Richard L. Rennert, Charles Goldstein
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Patent number: 6090070Abstract: A sale unit for the parenteral application of liquid pharmaceutical products by the user is described, whereby the unit comprises at least one cannula, a device to emit a given liquid amount of the pharmaceutical product in single doses, as well as at least one vessel filled with the pharmaceutical product, the vessel being arranged within the device and emptied in single doses by means of the device, and whereby each single dose corresponds to the given liquid amount of the pharmaceutical product.Type: GrantFiled: February 10, 1997Date of Patent: July 18, 2000Assignee: Rhone-Poulenc Rorer GmbHInventors: Jorg-Christian Hager, Kurt Gebhart, Helmut Lowenich, Ulrich Pastewka
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Patent number: 6033384Abstract: A medicament-dispensing system includes a cartridge for housing and actuating an accordion-like vial-dispenser for dispensing a calibrated amount of medicament by means of a single actuation motion which sequentially loads the vial-dispenser and dispenses the loaded medicament. The vial-dispenser has a front bellows portion, a rear bellows portion, an internal piston mechanism, a medicament storage chamber and a dosage cavity. The cartridge has a trigger mechanism which acts in concert with a notched lever and a wedge-shaped arm internally located in the cartridge to sequentially load the dosage cavity with medicament and discharge it. Depression of the trigger mechanism simultaneously extends, by means of the notched lever, the front bellows portion and compresses the rear bellows portion to load the dosage cavity with medicament.Type: GrantFiled: December 18, 1997Date of Patent: March 7, 2000Inventor: Daniel Py
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Patent number: 5688251Abstract: A medication delivery pen is provided having a medication cartridge holder assembly, a pen body assembly and a cap. The reusable pen body assembly includes an improved loading and priming mechanism that allows the user to easily load a new cartridge and prime the pen without having to manually manipulate the pen's lead screw and related driving components.Type: GrantFiled: September 19, 1995Date of Patent: November 18, 1997Assignee: Becton Dickinson and CompanyInventor: Lawrence H. Chanoch
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Patent number: 5584815Abstract: A multi-cartridge dispenser for delivering two liquid medications through a single needle. The dispenser includes independent dual channel metering mechanism, dual channel drive mechanisms, and dual channel lock and pullback mechanisms. The wing must be in its "up" position for metering to take place. The wing reciprocatingly moves a driver between a pre-injection position and a post-injection position to reciprocatingly advance the leadscrews upon an injection stroke. The dosage indicator automatically rotates to its initial zero position upon the injection stroke. The lock and pullback mechanism automatically prevents rotation of the leadscrew upon metering and injection. It also locks out the cartridge retainers so that the retainers can be removed from the housing only while the wing is in its "down" position. The pullback sleeve unloads a pullback key during a cartridge change in order to enable the leadscrew to be spun freely back to its home position.Type: GrantFiled: April 19, 1995Date of Patent: December 17, 1996Assignee: Eli Lilly and CompanyInventors: Gerhard E. F. Pawelka, Christopher J. Stringer, Matthew Marsh, David L. Karshmer, Christopher O. Lada, Stephen J. Schoenberg
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Patent number: 5545144Abstract: A liquid preparation of a pharmaceutically active agent having a defined composation is repeatedly dosed from a multi-dose container having a defined volume. The amount dosed is selected as 1/N of the volume of the multi-dose container, N being an integer having a value of 2 or higher.A device for dosing a liquid preparation comprises a holder (1) for a multi-dose container (2), which has a movable rear wall (5) acting as a piston for expelling the liquid preparation (6) from the container, and a piston rod (7), which is provided with releasable blocking means (11, 14, 19, 22), such that the movement of the piston rod is limited to a preset length (35) corresponding to an expelled volume of 1/N of the volume of said multi-dose container, N being an integer having a value of 2 or higher.A preferred embodiment of the device is as an injection device for repeated parenteral injections from an injection cartridge.Type: GrantFiled: September 26, 1994Date of Patent: August 13, 1996Assignee: Pharmacia ABInventors: Linda Fryklund, Birger Hjertman, Marie-Louise Gustavsson, Jacob Kaluski, Gustav Levander, Olle Ljungquist, Anders Strom, Jonas Virding
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Patent number: 5439452Abstract: A closed-system, combination infusion and flush set which enables safe administration of both medicaments and flush solutions to a patient with great accuracy using conventional large volume parenteral bags. The administration set comprises a specially designed rotatable valve member for controlling fluid flow through the set and includes a stop post which positively blocks rotation of the valve member to a position that permits the flow of flush solution toward the patient.Type: GrantFiled: January 31, 1994Date of Patent: August 8, 1995Assignee: Children's Medical Ventures, Inc.Inventor: Read S. McCarty
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Patent number: 5383865Abstract: A medication dispensing device comprising a cartridge for containing an injectable product therein and an injector attached to the cartridge. The injector includes a drive mechanism comprising a dosage sleeve having a dosage knob at the proximal end thereof and a threaded rod coupled to the sleeve and axially advanceable into the cartridge upon clockwise rotation of the knob for dialing up a desired dosage to be injected. A ratchet mechanism is disposed in the injector housing and includes a rotatable piece secured to the dosage sleeve for rotation therewith and a locking seat in engagement with the rotatable piece. The ratchet mechanism permits rotational movement of the sleeve in the clockwise direction only. A disengaging mechanism is secured to the housing of the LCD assembly and includes a pin that extends into and engages the rotatable piece of the ratchet mechanism such that axial movement of the pin causes corresponding axial movement of the stationary piece.Type: GrantFiled: March 15, 1993Date of Patent: January 24, 1995Assignee: Eli Lilly and CompanyInventor: Peter Michel
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Patent number: 5376081Abstract: A syringe comprising a completely opaque barrel (2) and a plunger (3) having at least two measuring scales (6, 6'; 7, 7') , wherein one scale includes ascending numeral values and the other includes descending numeral values having a common index made of a rectilinear end (8) of the base of the cylinder.Type: GrantFiled: December 11, 1991Date of Patent: December 27, 1994Inventor: Salvatore Sapienza
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Patent number: RE41956Abstract: A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member.Type: GrantFiled: May 4, 2005Date of Patent: November 23, 2010Assignee: Novo Nordisk A/SInventors: Peter Christian Klitgaard, Steffen Hansen, Bo Radmer, Claus Schmidt Moller