Body Piercing Condit (e.g., Needle, Etc.) Patents (Class 604/272)
  • Patent number: 11065429
    Abstract: Provided is a method of producing a microneedle array unit which is capable of suppressing damage to a microneedle array.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: July 20, 2021
    Assignee: FUJIFILM Corporation
    Inventors: Yuka Kobayashi, Yasuhiro Sekizawa
  • Patent number: 11059194
    Abstract: A functional polymeric cutting edge structure and methods for manufacturing cutting edge structures using polymeric materials are provided. A razor blade for use in a razor cartridge or a blade box for assembly in a razor cartridge frame may be formed using the present invention.
    Type: Grant
    Filed: June 21, 2016
    Date of Patent: July 13, 2021
    Assignee: The Gillette Company LLC
    Inventors: Matthias Gester, Roman Kiyan, Ulf Hinze, Kestutis Kurselis
  • Patent number: 11020107
    Abstract: A suture capturing device configured to attain multiple preset orientations, comprising: a handle; a hollow shaft coupled to said handle; a rigid needle element configured with a hook for catching a suture and where the needle element is operatively coupled to the hollow shaft opposite the handle and configured to be slidable in a first direction to assume an open orientation where the hook is exposed relative to the hollow shaft and in a second direction to assume a closed orientation where the hook is not exposed relative to the hollow shaft.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: June 1, 2021
    Assignee: T.A.G. Medical Devices—Agriculture Cooperative Ltd.
    Inventors: Aryeh Mirochinik, Shai Nachmias, Roy Zilberman
  • Patent number: 10987503
    Abstract: A skin treatment can include applying a microneedle device to a region of the skin so that microneedles of the device penetrate the stratum corneum. The arrangement of microneedles can have first microneedles with a first length and second microneedles with a second length, different from the first length. The first and second microneedles can be formed from a mixture of a polymeric material and an active agent beneficial to skin. After the device is applied to the skin, the first and second microneedles can be released below the skin surface, followed by dissolution of the first and second microneedles.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: April 27, 2021
    Assignee: ALLERGAN, INC.
    Inventors: Justin J. Schwab, Michael Augarten, Zachary Dominguez, Ethan Franklin, Edwin J. Kayda, Jason Metzner
  • Patent number: 10952895
    Abstract: A phacoemulsification needle (100, 100A, 100B, 1000, 100D, 200, 200A) is provided for emulsifying body tissue. The needle (100, 100A, 100B, 1000, 100D, 200, 200A) is adapted to be attached to a phacoemulsification handpiece that imparts a vibration to the needle (100, 100A, 100B, 100C, 100D, 200, 200A). The needle (100, 100A, 100B, 1000, 100D, 200, 200A) has a body (104, 220, 220A) with a distal end (99), a proximal end (106), and an aspiration passage (124) extending between the proximal and distal ends (99, 106). The aspiration passage (124) defines a longitudinally-extending central body axis (110, 110A, 110B, 1100, 110D). The aspiration passage (124) is enlarged at the distal end (99) to define a tip (102, 102A, 102B, 1020, 102D, 210, 210A).
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: March 23, 2021
    Inventors: Takayuki Akahoshi, Ravi Nallakrishnan
  • Patent number: 10953152
    Abstract: A piercing part for a medical infusion system includes a piercing mandrel through which at least one channel extends and which has a mandrel tip whose first jacket surface part is tapered, relative to a central longitudinal axis, towards a front end. An opposite second jacket surface part has an inclined cutting face interrupted towards the front end. The piercing part can be used for medical transfusion and infusion appliances.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: March 23, 2021
    Assignee: B. BRAUN MELSUNGEN AG
    Inventors: Christof Schlitt, Manfred Lutz
  • Patent number: 10933173
    Abstract: A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: March 2, 2021
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Konstantinos Tsioris, Fiorenzo G. Omenetto, Eleanor M. Pritchard
  • Patent number: 10925618
    Abstract: A rongeur including a base, which includes a handle portion, a body portion and a shaft portion. The shaft portion is made of a metal material and includes a male mold-on interlock portion configured to non-removably interlock with an over-molded plastic material. The body portion is made of plastic material and includes an over-mold interlock portion that is over-molded onto and non-removably fixed onto the mold-on interlock portion of the shaft portion. A slide shaft of the rongeur includes a distal portion and a proximal portion. The distal portion is made of a metal material and includes a male mold-on interlock portion configured to non-removably interlock with an over-molded plastic material. The proximal portion is made of a plastic material and includes an over-mold interlock portion that is over-molded onto and non-removably fixed onto the mold-on interlock portion of the distal portion.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: February 23, 2021
    Assignee: STERIBITE, LLC
    Inventors: John A. Redmond, Mark T. Whiteaker
  • Patent number: 10912542
    Abstract: Disclosed embodiments include catheter assemblies, systems for sampling a targeted region of tissue, and methods of sampling a targeted region of tissue. In an illustrative, non-limiting embodiment, a catheter assembly includes: a catheter defining a lumen therein, a wall of the catheter defining an opening therein at a distal end of the catheter; and a curved flexible needle disposable in the lumen and being extendable from the opening at the distal end of the catheter at an angle that diverges from an axis of the lumen.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: February 9, 2021
    Assignee: Spiration, Inc.
    Inventors: Madeline C. Graham, Matthew E. Nickeson
  • Patent number: 10835285
    Abstract: Devices, systems, and methods for delivering a substance within a mammalian luminal organ or area adjacent thereto. In at least one exemplary embodiment of a system of the present disclosure, the system comprises an inner delivery device, comprising an inner portion configured to receive a substance therein, a pock tip at or near a distal end of the inner delivery device, the pock tip configured to deliver the substance from the inner portion, through a pock tip aperture defined within the pock tip, and into a mammalian tissue and/or luminal organ, and an embolus positioned within the inner portion, the embolus configured so that the substance remains distal to the embolus when the substance is positioned within the inner portion.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: November 17, 2020
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Jose A. Navia, Sr.
  • Patent number: 10773019
    Abstract: An infusion system comprises an infusion set (30) with one or more advanced features including tube set strain relief (10), infusion pumps having heat exchange abilities and two-direction pumping abilities (100), Piezo pump devices (200), reservoirs (220, 240) made from expanded tubing, and oil impregnated pump plungers (302). An exemplary strain relief (10) includes an adhesive layer (12) such as pressure sensitive adhesive (PSA) secured to a base (14). The base (14) rotatably receives a pin (18) of a tube holder (16). The pin (18) is captured within an opening (22) of the base (14) to allow 360 degree rotation of the tube holder (16).
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: September 15, 2020
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Gary M. Searle, Charles G. Hwang
  • Patent number: 10709884
    Abstract: Disclosed are devices for delivering a rheumatoid arthritis drug across a dermal barrier. The devices include microneedles for penetrating the stratum corneum and also include structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. The pattern of structures on the surface of the microneedles may include nano-sized structures.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: July 14, 2020
    Assignee: SORRENTO THERAPEUTICS, INC.
    Inventor: Russell Frederick Ross
  • Patent number: 10709846
    Abstract: User-friendly attachment mechanisms for pen needles provide improved handling and ease of use, including locking installation and removal features and sensory feedback when a needle-bearing hub is seated on a pen. Embodiments include a needle-bearing hub includes a circumferentially oriented flexible tab that engages a radially inward rib on an outer cover to assist in attaching a pen device to the pen needle.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: July 14, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Sudarsan Srinivasan, Michael DiBiasi, Sean Sullivan, Keith Knapp, Joshua Herr, Amit Limaye, David Huang, David Schiff, Todd Sack
  • Patent number: 10702637
    Abstract: The present invention relates to a guiding needle for a suction tube, which is for increasing accuracy and preventing medical accidents by enabling an operator to accurately recognize the bent direction of the needle and to stably hold the needle by means of a handle portion formed inside the rear end of the needle connected to a tube or by means of a separate fixing handle coupled to the inside of the rear end of the needle. In other words, the present invention relates to a needle having the rear end thereof coupled to one end of a tube connected to a drainage container for discharging body blood of a patient, wherein the needle has a coupling part formed inside the rear end thereof and comprises a fixing handle detachably coupled to the coupling part.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: July 7, 2020
    Assignees: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY, CHONBUK NATIONAL UNIVERSITY HOSPITAL, SUNGWON MEDICAL CO., LTD.
    Inventors: Jong Kwan Park, Jun Sung Park
  • Patent number: 10632290
    Abstract: A catheter assembly comprises a collar assembly comprising a coupling portion proximate the second end and a first compression member configured to removably engage the coupling portion. The catheter assembly further comprises a wing assembly that includes a housing configured to at least partially receive a cannula. The wing assembly also comprises two or more wings extending radially from the housing and a second compression member configured to removably engage a coupling portion. A tube is configured to fluidly couple the collar assembly to the wing assembly, and wherein a portion of the tube is retained by the first and second compression members.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: April 28, 2020
    Assignee: Tessy Plastics Corporation
    Inventors: David R. Young, Francis George Tatu, Willie Werner, Vincent Pilletteri, Stafford Frearson, Mark Lattimore
  • Patent number: 10624843
    Abstract: A microprojection array comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a therapeutic agent that is poorly soluble in water or an aqueous solvent.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: April 21, 2020
    Assignee: Corium, Inc.
    Inventors: Zhongli Ding, Guohua Chen, Parminder Singh
  • Patent number: 10603477
    Abstract: A skin treatment device is provided including bioerodible polymeric microneedles which are designed to more effectively deliver beneficial agents to the skin. The device includes a flexible substrate and an arrangement, for example, an array, of microneedles projecting from the substrate.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: March 31, 2020
    Assignee: Allergan, Inc.
    Inventors: Justin J. Schwab, Michael Augarten, Zachary Dominguez, Ethan Franklin, Edwin J. Kayda, Jason Metzner
  • Patent number: 10595833
    Abstract: The present invention relates to a surgical device. The surgical device may include: a needle device; an aspiration device, which is attached to or detached from the needle device, for tissue sampling; an injection device, which is attached to or detached from the needle device, for drug injection; and an electrode device, which is attached to or detached from the needle device, for thermal treatment. Therefore, any one of the aspiration device, the injection device, and the electrode device is attached to or detached from the needle device, thereby being capable of performing tissue sampling, drug injection, and thermal treatment. Thus, the time and costs required for tissue sampling, drug injection, and thermal treatment are reduced and foreign substances can be prevented from flowing into a surgical site in advance.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: March 24, 2020
    Assignee: STARMED CO., LTD.
    Inventors: Kyung Hoon Shin, Dong Un Kim, Hyuk Lim
  • Patent number: 10576257
    Abstract: An article comprising at least one microneedle is provided. The article can comprises a first side and a second side opposite the first side. The first side comprises a central cavity portion and a platform portion, with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle comprises a body comprising an outer surface; a base segment having a base and a first shape; a tip segment having a tip and a second shape, wherein the second shape is distinct from the first shape; a transition plane that delineates the base segment and the tip segment; and a central axis. Methods of using the article are also provided.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: March 3, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Dennis G. Berry, Paul A. Martinson, Chin-Yee Ng, Ryan Patrick Simmers
  • Patent number: 10576188
    Abstract: A coating agent that has excellent durability and a medical instrument (for example, a needle) that has been coated with the coating agent, are provided. The coating agent includes a condensate (1) of a compound represented by the following general formula (1-1) with a compound represented by the following general formula (1-2), a polydiorganosiloxane (2), and an amino-group-containing polyorganosiloxane (3). The content ratio of the polydiorganosiloxane (2) is 30 to 75 mass %, based on the total mass of the condensate (1), the polydiorganosiloxane (2), and the amino-group-containing polyorganosiloxane (3).
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: March 3, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Teruyuki Yatabe
  • Patent number: 10532200
    Abstract: A device that may be placed on a biological barrier can be used to perforate the biological barrier for a variety of purposes such as cosmetic, scar treatment or for the delivery of active agents. A flexible substrate has a first side and a second opposing side and a plurality of micro-penetrator arrangements each comprising a head and a first and second projection, for penetrating a biological barrier, extending from the head. The first and second projection at least partially extend through the flexible substrate towards the first side. The head comprises an elongate arm for spacing apart the first and second projections. A force is applied to the second side causing flexing of the flexible substrate and pushing the projections into communication with a biological barrier.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: January 14, 2020
    Assignee: Xobaderm Limited
    Inventor: Andrew James Kirby
  • Patent number: 10500771
    Abstract: A method of manufacturing a needle shaped body includes forming on a surface of a substrate a needle shaped portion having a bottomed hole that extends from a tip to the substrate, contacting the tip of the needle shaped portion with a surface of a liquid in an atmosphere at a first pressure lower than atmospheric pressure, increasing the first pressure to a second pressure while the tip is in contact with the surface of the liquid such that the liquid is filled into the bottomed hole, and freeze-drying the liquid filled in the bottomed hole.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: December 10, 2019
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Ryoichi Asai, Tomoya Sumida
  • Patent number: 10470781
    Abstract: Medical devices such as osteotomes are provided. The medical device may include inner and outer members that form a working end portion. Distal end portions of the inner and outer members can cooperate to allow deflection of the working end portion. Medical devices including indicators are also provided. The indicator may communicate a direction of deflection of the working end portion to a practitioner. Additionally, medical devices including torque release mechanisms are provided. The torque release mechanism may uncouple a first portion of the medical device from a second portion of the medical device when an amount of torque applied to the medical device exceeds a predetermined value. The torque release mechanism may limit damage to components of the medical device during use of the medical device.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: November 12, 2019
    Assignee: DFine, Inc.
    Inventors: Craig Purdy, Dan Balbierz, Nate Shirley, Jose Galdos
  • Patent number: 10463797
    Abstract: An incremental syringe is provided and includes a syringe barrel, a finger grip disposed at the proximal end of the syringe barrel, a tab disposed inside the syringe barrel, and a plunger body having detents, wherein the detents are configured to interact with the tab to provide audible and tactile feedback to a user when the plunger body is pushed through the syringe barrel in a distal direction.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: November 5, 2019
    Assignee: URO-1, INC.
    Inventors: Phillip Jack Snoke, Philip Morrison Allred, III, John Joseph Smith
  • Patent number: 10456504
    Abstract: An acicular body includes a support plate having a brightness of 5.0 or less, and a needle disposed on the support plate. The needle includes a tip formed to pierce a skin and a light transmission area which is located in an area including the tip and has a total light transmittance of 20% or more.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: October 29, 2019
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Hiroyuki Kato, Takako Yamamoto
  • Patent number: 10441691
    Abstract: A device for removing fluid from a body, the device comprising an array of microneedles and a housing; the array of microneedles being disposed within the housing and the housing defining a chamber. The microneedles are moveable between a disengaged position and an engaged position where, in use in the engaged position, the microneedles penetrate the surface of a body. The chamber is adapted to surround the surface of the body through which the microneedles penetrate when in the engaged position. The chamber is configured for connection to a vacuum device such that negative pressure can be applied to the chamber.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: October 15, 2019
    Assignee: Renephra Limited
    Inventors: Simon Todd, Ian Middleton
  • Patent number: 10434265
    Abstract: A medical hollow needle assembly includes an outer cylindrical body including a through-hole; a hollow needle having an outer peripheral surface, wherein a proximal portion of the hollow needle is disposed in the through-hole of the outer cylindrical body, and wherein the outer peripheral surface of the hollow needle has an outer reduced-diameter surface that has a smaller outer diameter than that of a more proximal portion of the outer peripheral surface of the hollow needle; and an inner cylindrical body including an insertion hole in which the hollow needle is disposed, wherein the inner cylindrical body is disposed between the hollow needle and an inner peripheral surface of the through-hole of the outer cylindrical body, and wherein the inner cylindrical body joins the outer cylindrical body and the hollow needle.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: October 8, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Tetsuya Ooyauchi, Kenta Gotou, Yukio Imai, Hidenori Fujiwara, Madoka Horie, Hideo Kawamoto, Ayumi Kumagai
  • Patent number: 10434034
    Abstract: A vial access device includes a housing having first and second connectors, with the first connector configured to be secured to a first container and the second connector configured to be secured to a second container. The device also includes a spike member extending from the housing and having a proximal end and a distal end. The spike member defines a vent lumen and a fluid lumen spaced from the vent lumen, with each of the vent lumen and the fluid lumen having a distal opening. The distal openings of the vent lumen and the fluid lumen are each defined by a top edge and a bottom edge spaced axially from the top edge. The bottom edge of the fluid lumen is positioned above the distal opening of the vent lumen in a direction extending along a longitudinal axis of the spike member.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: October 8, 2019
    Assignee: Becton Dickinson and Company Ltd.
    Inventor: Alexander Cederschiöld
  • Patent number: 10398885
    Abstract: An article (100) comprising at least one microneedle (160) is provided. The article comprises a first side (112) and a second side (114) opposite the first side. The first side comprises a central cavity portion (120) and a platform portion (130), with at least one microneedle extending therefrom, wherein the platform portion is not coplanar with the central cavity portion. The platform portion substantially surrounds the central cavity portion. The at least one microneedle comprises a body comprising an outer surface (163); a base segment (166) having a base (162) and a first shape; a tip segment (168) having a tip and a second shape, wherein the second shape is distinct from the first shape; a transition plane (167) that delineates the base segment and the tip segment; and a central axis (180). Methods of using the article are also provided.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: September 3, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: Michael J. Frits, Craig S. Moeckly, Daniel H. Berg, Jerome E. Gysbers, Ryan Patrick Simmers
  • Patent number: 10368911
    Abstract: Novel and unique medical devices and associated methods are disclosed, for facilitating efficient and repeatable puncture of a tissue site while allowing vascular access from various access sites of a patient's body. Disclosed medical devices include dilators and wires usable alone or in combination and configured to facilitate tissue access and puncture at various anatomical locations from desired access sites. The medical devices each include one or more sections having sufficient flexibility for accessing the tissue site from the access site while retaining sufficient stiffness to perform one or more additional functions.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: August 6, 2019
    Assignee: Baylis Medical Company Inc.
    Inventors: Gareth Davies, John Paul Urbanski, Ferryl Alley, Bogdan Beca
  • Patent number: 10363379
    Abstract: A safety device for a medicament container includes a first sheath having a first ledge and a second ledge, a second sheath telescopically arranged with the first sheath and releasably coupled to the first ledge, and a finger flange having at least one resilient clip adapted to engage the second ledge first sheath.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: July 30, 2019
    Assignee: Sanofi
    Inventors: David Darras, Fabien Canepa, Bruno Serre, Jacky Mazzolini
  • Patent number: 10363394
    Abstract: Systems and methods are disclosed herein that generally involve CED devices with various features for reducing or preventing backflow. In some embodiments, CED devices include a tissue-receiving space disposed proximal to a distal fluid outlet. Tissue can be compressed into or pinched/pinned by the tissue-receiving space as the device is inserted into a target region of a patient, thereby forming a seal that reduces or prevents proximal backflow of fluid ejected from the outlet beyond the tissue-receiving space. In some embodiments, CED devices include a bullet-shaped nose proximal to a distal fluid outlet. The bullet-shaped nose forms a good seal with surrounding tissue and helps reduce or prevent backflow of infused fluid.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: July 30, 2019
    Assignee: Alcyone Lifesciences, Inc.
    Inventors: Deep Arjun Singh, P J Anand, Blake Sama
  • Patent number: 10363406
    Abstract: A method for producing an acicular body having a support base and an acicular protrusion on one surface of the support base includes supplying an acicular body-forming liquid, in which an acicular body-forming material is dissolved or dispersed in a solvent, to an intaglio plate having a recess corresponding to a protrusion, under a first pressure environment of not more than 0.05 MPa, changing the first pressure environment of the acicular body-forming liquid supplied to the intaglio plate to a second pressure environment of higher than 0.05 MPa, drying the acicular body-forming liquid supplied to the intaglio plate such that an acicular body is formed, and peeling the acicular body from the intaglio plate.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: July 30, 2019
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventor: Hiroyuki Kato
  • Patent number: 10342964
    Abstract: The invention is a microneedle preparation administration apparatus comprising: a guide tube; a pedestal in which at least a part thereof including a front end surface is housed within the guide tube and slides in length direction; and driving means for driving the pedestal toward a front end part of the guide tube, and microneedle preparations being to be attached to the front end surface of the pedestal.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: July 9, 2019
    Assignee: Labo Juversa Co., Ltd.
    Inventors: Kanji Takada, Ichiro Ono
  • Patent number: 10327821
    Abstract: The present application is directed to devices and methods for treating vertebral fractures with one or more bone pins. In one embodiment of a method, a fractured vertebral body may be accessed through a pedicle portion and an opening may be created therethrough. One or more bone pins may be inserted through the opening. In one embodiment, at least one of the inserted bone pins is inserted to extend across a fracture zone with a proximal portion of the pin engaging a first bone segment and a distal portion engaging a second bone segment. The pin or pins may be manipulated to immobilize the first and second portions of the fractured vertebra.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: June 25, 2019
    Assignee: Globus Medical, Inc.
    Inventors: David C. Paul, Sean Suh
  • Patent number: 10292724
    Abstract: A perforation instrument and method of using same, including a shaft capable of being inserted into a joint of a patient, having a longitudinal axis, and carrying at least one piercing member, each piercing member having a tip suitable to pierce sub-chondral bone. The instrument is capable of being altered between an exposed condition wherein the tip of the at least one piercing member is exposed and a safety condition wherein the tip of the at least one piercing member is not capable of piercing tissue.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: May 21, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: John R. Cournoyer, Dina Belloli, Jonathan Correia, Scott Woodruff, Bethany F. Grant, Joseph Hernandez
  • Patent number: 10292861
    Abstract: A device configured for use in an ocular surgical procedure is provided. The device, such as a sleeve or a needle, includes a proximal portion, a distal portion including at least one fluid opening formed at a predetermined orientation, and at least one visual marking provided at the proximal portion at a predetermined marking orientation relative to said predetermined orientation. The visual marking or markings provide a visual indication of orientation of the fluid opening when the device is employed in the ocular surgical procedure.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: May 21, 2019
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventor: James Gerg
  • Patent number: 10201345
    Abstract: Systems and methods are provided for suturing tissue. An elongated deployment shaft carries a needle deployment assembly with needles carrying suture material. A needle catcher is disposed over the shaft and configured to engage and retain at least a portion of each of the needles carrying the suture material when the needles are passed through the tissue to be sutured to a proximal position.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: February 12, 2019
    Assignee: Terumo Medical Corporation
    Inventors: Yu-Shih Weng, Shih-Jui Han, Shih-Ming Wang, Chung-Chu Chen, Hsiao-Wei Tang, Chun-Chia Juan
  • Patent number: 10143448
    Abstract: The invention relates to a biopsy device comprising a needle extending longitudinally from a proximal end to a distal end and including a channel extending there through. At least one section (6) of the needle (3) is provided with a curved shape, so that tissues that normally would be out or reach of conventional needles can be targeted.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: December 4, 2018
    Inventor: Philippe Brunner
  • Patent number: 10092299
    Abstract: A disposable kerrison rongeur. A base includes a handle portion, a body portion and a shaft portion. The shaft portion is made of a metal material and includes a male mold-on interlock portion configured to non-removably interlock with an over-molded plastic material. The body portion is made of plastic material and includes an over-mold interlock portion that is over-molded onto and non-removably fixed onto the mold-on interlock portion of the shaft portion. A slide shaft includes a distal portion and a proximal portion. The distal portion is made of a metal material and includes a male mold-on interlock portion configured to non-removably interlock with an over-molded plastic material. The proximal portion is made of a plastic material and includes an over-mold interlock portion that is over-molded onto and non-removably fixed onto the mold-on interlock portion of the distal portion.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: October 9, 2018
    Assignee: STERIBITE, LLC
    Inventors: John A. Redmond, Mark T. Whiteaker
  • Patent number: 10071231
    Abstract: A medical instrument is that the first holding portion or the second holding portion is capable of moving so that a distance between a distal end of the first holding portion and a distal end of the second holding portion changes from a first dimension which is larger than a diameter of the wire to a second dimension which is smaller than the diameter of the wire and the space is formed by the first holding portion and the second holding portion such that the wire is capable of rotating about a line connecting a first contact point where the first protrusion portion contacts with the wire with a second contact point where the second protrusion portion contacts with the wire.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: September 11, 2018
    Assignee: OLYMPUS CORPORATION
    Inventors: Takuo Yokota, Rei Matsunaga
  • Patent number: 10052458
    Abstract: A needle steering system and apparatus provides active, semi-autonomous control of needle insertion paths while still enabling a clinician ultimate control over needle insertion. The present teaching describes a method and system for controlling needle path as the needle is inserted by precisely controlling the rotation of the needle as it continuously rotates during insertion. This enables underactuated 2 degree-of-freedom (DOF) control of the direction and the curvature of the needle from a single rotary actuator. Control of the rotary motion is therefore decoupled from the needle insertion. The rotary motion controls steering effort and direction, while the insertion controls needle depth or insertion speed. In one implementation, the proposed method does not require constant velocity insertion, interleaved insertion and rotation, or known insertion position or speed. The insertion may be provided by a robot or other automated method, may be a manual insertion, or may be a teleoperated insertion.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: August 21, 2018
    Assignee: WORCESTER POLYTECHNIC INSTITUTE
    Inventors: Gregory S. Fischer, Hao Su
  • Patent number: 10022366
    Abstract: Microneedles and their use as a physical skin permeation enhancement technique facilitate drug delivery across the skin in therapeutically relevant concentrations. Micropores created in the skin by MNs reseal because of normal healing processes of the skin, thus limiting the duration of the drug delivery window. Pore lifetime enhancement strategies can increase effectiveness of MNs as a drug delivery mechanism by prolonging the delivery window. Fluvastatin (FLU) was used to enhance pore lifetime by inhibiting the synthesis of cholesterol, a major component of the stratum corneum lipids. The skin recovered within a 30-45-min time period following the removal of occlusion, and there was no significant irritation observed due to the treatment compared to the control sites. Thus, it can be concluded that localized skin treatment with FLU can be used to extend micropore lifetime and deliver drugs for up to 7 days across MN-treated skin.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: July 17, 2018
    Assignees: University of Maryland, Baltimore, University of Kentucky Research Foundation
    Inventors: Audra L. Stinchcomb, Priyanka Ghosh
  • Patent number: 10004548
    Abstract: Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: June 26, 2018
    Assignee: Silver Bullet Therapeutics, Inc.
    Inventors: Houdin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
  • Patent number: 9895497
    Abstract: The present invention relates to a method of producing syringes. Said method comprises fixing a needle to a syringe body by use of an adhesive followed by subjecting the syringes thus obtained to heat treatment. The invention further relates to a method of reducing leachables and/or extractables in prefilled syringes, said method comprising heat treating pre-fabricated syringes at a temperature of at least 40° C. before filling.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: February 20, 2018
    Assignee: Hexal AG
    Inventor: Peter Skufca
  • Patent number: 9855402
    Abstract: A surgical apparatus for delivering fluid to treat renal hypertension including an elongated member having a distal tip and a plurality of openings formed in a sidewall proximal of the distal tip. A plurality of fluid delivery members are movably positioned in the elongated member, each of the fluid delivery members having a lumen and at least one opening communicating with the lumen for delivering fluid extravascularly. An actuator is operatively associated with the fluid delivery members, the actuator actuable to a first position to move the fluid delivery members from a retracted position within the elongated member to a deployed position extending radially with respect to the elongated member. A balloon is expandable radially from the elongated member to seal the renal artery during application of fluid through the fluid delivery members.
    Type: Grant
    Filed: December 20, 2014
    Date of Patent: January 2, 2018
    Assignee: Rex Medical, L.P.
    Inventor: James F. McGuckin, Jr.
  • Patent number: 9833248
    Abstract: Methods and devices for harvesting cancellous bone are disclosed. The bone-harvesting device may include a cannula and a bone receptacle in communication with the cannula, wherein the cannula including a cutting surface positioned at or adjacent the distal end, the cutting surface being oriented at an angle, the angle being greater than 90 degrees relative to the longitudinal axis of the cannula, and the harvested bone is adapted to move from a position adjacent to the cutting surface through the cannula into the bone receptacle. The cutting surface of the cannula may be positioned at or adjacent the distal end, and positioned at least in part radially outward of the outer face of the cannula. The cannula may include a cutting surface positioned at or adjacent the distal end and an occluding geometry that partially occludes the distal end of the cannula adjacent the cutting surface. In addition, a suction port may be provided in communication with the bone receptacle.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: December 5, 2017
    Assignee: The John Hopkins University
    Inventors: Maxim Budyansky, Neil Shah, Akhil Jay Khanna, Khaled M. Kebaish, Lee H. Riley, III
  • Patent number: 9795429
    Abstract: A cannula device for removing, including by aspirating, bodily material is disclosed. The device may include a cannula and a hub. The cannula includes an open proximal end and a deflectable distal segment, and one or a plurality of distal orifices fluidly connected to the lumen. When distally extended from an outer guide cannula, the deflectable segment assumes a curved shape, which includes temperature-dependent curvature subject to elevated temperature along a memory metal length of the cannula.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: October 24, 2017
    Assignee: STRYKER CORPORATION
    Inventors: Evan D. Linderman, John A. Krueger
  • Patent number: 9782574
    Abstract: An applicator (100) for applying a microneedle device to a skin surface. The applicator can include a microneedle device (106), a housing (102), and a connecting member (110). The connecting member can be configured to allow the microneedle device to move between: (i) a first position in which at least a portion of the microneedle device extends beyond the housing; and (ii) a second position in which the microneedle device is recessed within the housing when a threshold application force is applied to the microneedle device in a direction substantially perpendicular with respect to the microneedle device.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: October 10, 2017
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventor: Ryan P. Simmers
  • Patent number: 9757063
    Abstract: A device for receiving a body fluid for analysis, comprising a container and at least one sample-receiving unit which can be impinged upon by the body fluid at a receiving point and which can be extracted from a guide chamber of the container by means of a drive unit. According to the invention, a coupling device is provided in order to couple the sample receiving unit to the drive unit to ensure back and forth movement between the guide chamber and the receiving point.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: September 12, 2017
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Klaus-Dieter Sacherer, Ronald Mönch, Michael Schabbach, Jörg Scherer