Adhesively Attachable To Body Patents (Class 604/307)
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Publication number: 20110238021Abstract: A transdermal delivery device is provided for delivering at least one active therapeutic compound to rapidly induce a therapeutic effect, the device comprising: a pad for receiving a depot of the at least one therapeutic compound, the pad having a portion of material of high compression resistance; and the device also comprising a backing layer of greater cross-section than the pad. A method for rapidly reducing a therapeutic effect and a transdermal delivery but for delivering at least one therapeutic compound to rapidly induce a therapeutic effect are also provided.Type: ApplicationFiled: September 21, 2009Publication date: September 29, 2011Inventor: Suzana Hillhouse
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Patent number: 8022266Abstract: A therapeutic device for promoting the healing of a wound in a mammal is disclosed. An exemplary device comprises a permeable structure having a plurality of depressions formed in a surface thereof. In use, the surface having the depressions is disposed adjacent a surface of the wound. A method of treating a wound comprises the steps of providing a permeable structure comprising a plurality of randomly disposed fibers and having i) a plurality of wound surface contact elements disposed between end portions of the structure, and ii) a plurality of voids defined by the contact elements; and applying the permeable structure to at least one surface of the wound.Type: GrantFiled: May 20, 2009Date of Patent: September 20, 2011Assignee: Boehringer Technologies, L.P.Inventors: John R. Boehringer, John Karpowicz, Amitabha Mitra, Christopher L. Radl
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Publication number: 20110218505Abstract: An antiemetic patch is provided. The antiemetic patch includes a backing layer, a release liner, and a matrix layer disposed between the backing layer and the release liner. The matrix layer includes an antiemetic composition, and the antiemetic composition includes an antiemetic agent ranged, a permeation enhancer and an adhesive.Type: ApplicationFiled: November 26, 2009Publication date: September 8, 2011Applicants: GENOVATE BIOTECHNOLOGY CO., LTD., STANDARD CHEM & PHARM CO., LTD., JIANBO INTERNATIONAL DEVELOPMENT LTD.Inventors: Jui-Mei Lu, Lih-Hua Lian, Li-Fen Yao
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Publication number: 20110218506Abstract: A transungual patch/device useful for the treatment of onychomycosis includes: (i) a backing medium; and (ii) an adhesive matrix layer deposited thereon which contains (a) a thus effective amount of amorolfine active agent or derivative thereof essentially uniformly distributed therethrough, dissolved or dispersed in the adhesive, and (b) at least one absorption promoter for enhancing the absorption of the amorolfine or derivative into the nail onto which the patch/device is applied, the at least one absorption promoter comprising either exaltolide alone, or at least two such absorption promoters selected from among urea, N-acetylcysteine and lactic acid.Type: ApplicationFiled: January 7, 2011Publication date: September 8, 2011Applicant: Galderma Research & DevelopmentInventors: Leslie ZANUTTO, Laurent Fredon, Claire Mallard
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Patent number: 8007491Abstract: The tissue therapy device includes a sealant layer and a suction apparatus. The sealant layer creates a sealed enclosure between it and the surface of a patient by forming an airtight seal around an area of tissue. The suction apparatus is in fluid communication with the sealant layer and together, create a closed, reduced pressure therapy system. The suction apparatus self-creates reduced pressure by decreasing the density of air molecules underneath the sealant layer by expanding the volume of the air molecules.Type: GrantFiled: September 19, 2008Date of Patent: August 30, 2011Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Moshe Pinto, Dean Hu, Kenton Fong
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Publication number: 20110190716Abstract: There is disclosed a transdermal drug delivery device for the pre-treatment and treatment of poisoning by highly toxic organophosphates, in the form of a matrix system comprising a backing layer, a drug containing adhesive layer and a release liner, in which the drug containing adhesive layer comprises a neutral polyacrylate without functionality having a uniform dispersion of a parasympathomimetic and a parasympatholytic therein.Type: ApplicationFiled: June 2, 2009Publication date: August 4, 2011Inventors: Timothy J. Easterbrook, Edward Gosden, Elizabeth Meyer
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Patent number: 7988680Abstract: A wound dressing member is provided for use in a vacuum bandage connected to a vacuum source. The wound dressing member is also provided for use with a wound having a wound surface. The wound dressing member includes a wound facing surface adapted to be in contact with and generally conform to the wound surface and a plurality of discrete holes formed in the wound facing surface. The member further includes a port configured to communicate with the vacuum source and with each hole formed in the wound facing surface. The wound dressing member further includes a stand-off having interconnected portions coupled to the wound facing surface and configured to provide a space between the wound facing surface and the wound surface.Type: GrantFiled: February 4, 2005Date of Patent: August 2, 2011Assignee: KCI Medical ResourcesInventors: Jeffrey S. Lockwood, Robert Petrosenko, James R. Risk, Jr.
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Publication number: 20110184356Abstract: This invention relates to an apparatus that regulates thermodynamic energy-flow within a human body for producing beneficial effects such as, for example, improvement in strength, improvement in stamina, pain relief, etc. According to one embodiment, the invention provides a wearable apparatus that may include biomolecular components for building-up of a thermomagnetic energy within the human body. According to another embodiment, the invention provides a wearable apparatus that may include biomolecular components for dilution of a thermomagnetic energy within the human body. According to yet another embodiment, the invention provides a wearable apparatus that may include biomolecular components having orthomolecular and/or non-orthomolecular organic materials which are capable of thermomagnetic levororotary action and/or thermomagnetic dextrorotatory action.Type: ApplicationFiled: October 29, 2010Publication date: July 28, 2011Applicant: LIFEWAVE PRODUCTS, LLCInventor: David Schmidt
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Patent number: 7985195Abstract: A dressing having a flexible sleeve shaped to accommodate a substantially cylindrical body or plant portion, the sleeve having a lining which is substantially non-adherent to the body or plant part being bandaged and having a peripheral securement means which attaches two peripheral portions to each other without those portions being circumferentially adhered to the sleeve portion.Type: GrantFiled: August 25, 2009Date of Patent: July 26, 2011Inventor: Barbara Brooke Jennings-Spring
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Patent number: 7985209Abstract: A wound or surgical dressing is disclosed. The wound or surgical dressing is configured to cover or surround a wound, a surgical incision, or any type of skin irritation. In accordance with the present disclosure, the wound or surgical dressing is treated with a bacteriostatic composition that is capable of binding and trapping negatively charged matter, such as bacteria, pathogens, and the like. The bacteriostatic composition comprises a cationic polymer, a cationic oligomer, or particles coated with a cationic material. The bacteriostatic composition is bonded to the wound or surgical dressing in a manner such that the bacteriostatic composition is not substantially transferred to a patient being treated.Type: GrantFiled: December 15, 2005Date of Patent: July 26, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Julie M. Villanueva, Curtis Neil Sayre, Lei Huang, Kevin Peter McGrath, Ning Wei
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Patent number: 7967810Abstract: Methods and systems are provided for a sub-atmospheric wound-care (SAWS) system for treating an open wound. The SAWS system includes a regulated vacuum source for developing a negative pressure, a flow rate meter configured to measure a flow rate of liquid removed from the wound, a primary pressure regulating sensor located proximate the wound for directly measuring the negative pressure at the wound, a backup pressure regulating sensor located vacuum tube, a porous dressing suitable to be sealed airtight which is positioned within a wound interface chamber, a collection canister configured to collect said liquid removed from the wound, and an adapter configured to use wall suction a primary regulated vacuum source.Type: GrantFiled: October 19, 2007Date of Patent: June 28, 2011Inventors: Brett A. Freedman, Robert L. Pauly
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Patent number: 7960602Abstract: The present invention provides a multilayer bandage, having a webbing for contacting a wound and a first membrane that has at least one water-insoluble polymer and is water-impervious. The present invention further provides methods for making the multilayer bandage, methods of using the multilayer bandage for accelerated wound healing, and kits having compositions of the present invention.Type: GrantFiled: December 30, 2005Date of Patent: June 14, 2011Assignee: Bayer Innovation GmbHInventors: Axel Thierauf, Iwer Baecker, Andreas Haisch
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Publication number: 20110137269Abstract: The invention concerns an occlusive or semi-occlusive dressing and a treatment kit for onychomycosis containing dressings according to the invention and a container of urea paste.Type: ApplicationFiled: July 31, 2009Publication date: June 9, 2011Applicant: PIERRE FABRE DERMO-COSMETIQUEInventors: Héla Coubetergues, Jean-Jacques Voisard
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Publication number: 20110125113Abstract: Provided is a device for providing a vacuum to a tissue, including a first tissue cover for covering the tissue and having first peripheral portion with a tissue facing contact surface adapted to be sealingly affixed to a first tissue portion surrounding the tissue, the device being adapted for enabling a vacuum to be selectively applied to the tissue in operation of the device; a substantially contiguous layer of flowable sealing material configured for covering a second tissue portion abuttingly adjacent at least a part of the first peripheral portion, where the sealing material is configured for filling gaps between the contact surface and the first tissue portion that may form leaks, by flowing towards the contact surface under suction provided when the vacuum is applied to the damaged tissue in operation of the device, and where the sealing material is uncoupled with respect to the contact surface at least prior to affixing the contact surface to the first tissue portion; and a second tissue cover coveriType: ApplicationFiled: June 23, 2009Publication date: May 26, 2011Inventor: Carmeli Adahan
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Patent number: 7938790Abstract: For application of active substances to a wound surface a porous padding (12) is provided upon the wound (10), which is sealingly covered over with a foil (14). A fluid active substance is introduced into the padding (12) via a supply line (22) and is then suctioned out of the padding (12) via a removal line (26). Closure mechanisms (32, 34) control the introduction of the active substance and the suctioning off of the active substance in the manner, that the active substance after being introduced remains for a predetermined dwell time in the padding (12), before it is suctioned off. After the suctioning off the vacuum in the padding (12) is maintained for a certain time period, before renewed introduction of the active substance. The opening of the closure mechanisms (32, 34) are temporally controlled to occur slowly.Type: GrantFiled: June 15, 2010Date of Patent: May 10, 2011Inventor: Wilhelm Fleischmann
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Publication number: 20110106022Abstract: A medical grade adhesive comprises a mixture of at least one cross-linkable pressure sensitive adhesive component and at least one non-cross-linkable pressure-sensitive adhesive component, wherein the amount of each of said components is such that the resultant adhesive can adhere to human skin for a period of up to about 7-10 days but can be removed without causing trauma to the skin.Type: ApplicationFiled: January 11, 2011Publication date: May 5, 2011Applicant: Mylan Technologies Inc.Inventors: Kristin Jackson, Kenneth James Miller, II
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Patent number: 7935085Abstract: A delivery device includes a durable housing portion and a separable disposable portion that selectively engage and disengage from each other. The disposable housing portion secures to the patient and may be disposed of after it has been in use for a prescribed period. Components that normally come into contact with a patient or with infusion media are supported by the disposable housing portion for disposal after the prescribed use, while the durable housing portion supports other components such as electronics for controlling delivery of infusion media from the reservoir and a drive device and drive linkage.Type: GrantFiled: January 28, 2010Date of Patent: May 3, 2011Assignee: Medtronic Minimed, Inc.Inventors: Sheldon B. Moberg, Ian B. Hanson, Paul S. Cheney, II
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Patent number: 7921999Abstract: A peelable pouch comprises a substantially flat enclosure formed by first and second opposing flexible plies. A seal extends along at least a portion of a perimeter of the opposing plies. A flat, flexible transdermal patch is disposed in the enclosure and includes a bioactive agent dissolved in a layer of adhesive. A release liner is removably attached over the layer of adhesive, with the patch and the release liner together being sufficiently resilient so as to generate a spring force when displaced out of the flat configuration. The first and the second plies each being separable along the seal and displaceable out of the flat configuration. The spring force generated by the patch and the release liner being sufficient to overcome an adhesive force created by the adhesive between the patch and one of the plies.Type: GrantFiled: December 21, 2006Date of Patent: April 12, 2011Assignee: Watson Laboratories, Inc.Inventor: Michael W. Kimball
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Publication number: 20110071482Abstract: Methods and devices for signaling to a subject or subject's care giver the occurrence of at least one event selected from: a) expiration or impending expiration of a predetermined time period and/or b) a change in a physiological or device-associated variable, associated with a medical device that is positioned on, in or connected to the subject's body.Type: ApplicationFiled: September 22, 2010Publication date: March 24, 2011Inventor: James R. Selevan
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Patent number: 7905852Abstract: A dressing having a flexible sleeve shaped to accommodate a substantially cylindrical body portion, the sleeve having a lining which is substantially non-adherent to the body part being bandaged and having a peripheral securement means which attaches two peripheral portions to each other without those portions being circumferentially adhered to the sleeve portion.Type: GrantFiled: August 29, 2008Date of Patent: March 15, 2011Inventor: Barbara Jennings-Spring
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Patent number: 7897683Abstract: The present invention provides a medical adhesive and a medical adhesive tape or sheet superior in the fixing performance, particularly perspiration-resistant fixing, which shows low skin irritation and suitable adhesive strength. The present invention provides a medical adhesive containing a water-dispersed copolymer obtained by copolymerizing 100 parts by weight of a monomer mixture containing (meth)acrylic acid alkyl ester and 0.Type: GrantFiled: May 21, 2007Date of Patent: March 1, 2011Assignee: Nitto Denko CorporationInventors: Atsushi Hamada, Tomonari Naito, Namiko Murayama, Miki Funahashi, Jun Ishikura
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Patent number: 7888546Abstract: An adhesive device used as a wound dressing, ingredient delivery device or IV hold-down in which inadvertent edge release of these devices along the periphery of the polymeric film layer is minimized when the handling layer, which is adhered to the polymeric film layer, is removed after application of the polymeric film layer to the patient.Type: GrantFiled: July 2, 2004Date of Patent: February 15, 2011Assignee: Corium International, Inc.Inventors: Michael G. Marcoux, David R. Johnson, Steven R. Klemm
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Patent number: 7883494Abstract: An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and over a biodegradable scaffold in contact with the wound bed (which encourages healing tissue growth from the wound bed). The apparatus has means (which includes the device(s)) for providing simultaneous aspiration and irrigation of the wound. A dressing assembly including the dressing and the scaffold, and the dressing and a method of treatment using the apparatus.Type: GrantFiled: October 28, 2005Date of Patent: February 8, 2011Assignee: Smith & Nephew PLCInventor: Robin Paul Martin
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Patent number: 7863496Abstract: A self-closing antiseptic plaster (1) for puncturing blood vessels, muscle tissue, tissue, skin, organs (biopsy) or bone marrow is puncturable by cannulas, needles or the like. It has a backing layer (2), a sealing layer (5) made of a material having an elastic restoring force and a skin adhesive layer (3) applied to the underside U of the backing layer (2), the sealing layer being applied to the backing layer (2) by means of an adhesive layer (4). The backing layer (2) is usually thin. The backing layer (2), the sealing layer (5), the adhesive layer (4) and the skin adhesive layer (3) are transparent or approximately transparent in the entire area or at least in a superimposed partial area. The backing layer (2) and the sealing layer (5) are made of thin and soft materials so that any puncture site is visible and/or palpable through the self-closing antiseptic plaster (1). The advantages include the fact that the antiseptic state at the puncture site is preserved before, during and after the puncturing.Type: GrantFiled: October 18, 2005Date of Patent: January 4, 2011Assignee: Vostra-Med AGInventors: Ernst-Diethelm Harren, Marc Ulrich Lehmann
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Publication number: 20100318042Abstract: Provided is an adhesive patch including a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a woven fabric knitted in stockinette stitch on both sides having two or more rows of crimped polyethylene terephthalate multifilament yarns, the adhesive layer contains 25 to 50% by mass of a liquid organic ingredient and 25 to 50% by mass of a thermoplastic elastomer based on the total mass of the layer and contains 10% by mass or more of methyl salicylate as the liquid organic ingredient based on the total mass of the layer, and the storage elastic modulus (G?) of the adhesive layer is 30000 to 75000 Pa at 10 rad/s and 37° C.Type: ApplicationFiled: January 22, 2009Publication date: December 16, 2010Applicant: HISAMITSU PHARMACEUTICAL CO., INC.Inventors: Tomomi Okada, Shigeo Ohta, Nobuo Tsutsumi
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Publication number: 20100305522Abstract: A fluid delivery device for transdermal delivery of a fluid to a patient. The device comprises an envelope that may be applied to a patient's skin. The envelope comprises at least one diffusion layer coupled to at least one impermeable layer such that at least a chamber is defined therebetween. Other embodiments include internal diffusion layers, and thus possess additional chambers, as well. In one arrangement, an adhesive boundary layer permits the device to be removably secured to a patient and inhibits radial migration of fluid beyond the periphery of the device. In another arrangement, preferably, an anti-microbial layer is provided to inhibit the growth of microorganisms.Type: ApplicationFiled: August 10, 2010Publication date: December 2, 2010Applicant: I-FLOW CORPORATIONInventors: ROGER MASSENGALE, KEVIN M. FORREST, BILL PORTER, DONALD M. EARHART, ALAN DINE
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Publication number: 20100298788Abstract: An adhesive patch, such as poultice-type patch, is provided, which is suitable for mass production and allows the user to apply it without touching the drug-containing matrix. A production method of such a adhesive patch is also provided. Specifically, the method for producing adhesive patch, wherein (a) the adhesive patch comprises two liners; (b) the first liner is folded at the middle thereof so that it is divided by the fold into two sections that together form a V-shaped liner, one of the two sections adhering to the drug-containing matrix surface; and (c) the second liner adheres to the remaining part of the drug-containing matrix surface with one end of the second liner covering the fold of the V-shaped first liner, the method including: allowing a tubular liner to adhere to at least half of the surface of the drug-containing matrix spread over the backing; and cutting the tubular liner in half to form the V-shaped first liner folded at the middle thereof.Type: ApplicationFiled: April 25, 2006Publication date: November 25, 2010Applicant: TEIKOKU SEIYAKU CO., LTD.Inventor: Masanori Uematsu
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Publication number: 20100292660Abstract: A method of enclosing an active ingredient layer between a release liner and a backing layer of a dermal patch by ultrasonically welding a seal between the backing layer and the release liner. A pressure sensitive layer is further provided between the backing layer and release liner.Type: ApplicationFiled: July 10, 2008Publication date: November 18, 2010Inventor: Agis Kydonieus
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Patent number: 7833208Abstract: An article for use in contact with a tissue layer of a person and capable of holding its position with respect to the contacted tissue layer while reducing the opportunity for damage to the tissue layer comprises a support structure and a contact layer associated with the support structure. The contact layer has an engagement surface adapted to contact the user's tissue layer. The contact layer is constructed so that the engagement surface has a first state adapted to inhibit movement of the article with respect to the tissue layer of the user, and a second state adapted to enhance movement of the article with respect to the tissue layer of the user. The engagement surface is adapted to transform from the first state to the second state upon application of a force greater than a threshold force.Type: GrantFiled: December 29, 2004Date of Patent: November 16, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: David W. Koenig, Wael R. Joseph
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Publication number: 20100286630Abstract: The invention relates to a method for treating overactive bladders and a device for storing and administering non-occluded oxybutynin topical compositions.Type: ApplicationFiled: May 5, 2009Publication date: November 11, 2010Applicant: WATSON LABORATORIES, INC.Inventors: Scott Gochnour, Venkatesh Subramanyan, Michael W. Kimball
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Patent number: 7828782Abstract: An object of the present invention is to provide a tissue cell culture system whereby a call tissue can be efficiently and quickly proliferated in vivo and the onset bacterial infection in an injured part can be avoided in the course of a treatment. More specifically, a closed cell culture system (1) characterized in that a defection (2) of a tissue on the body surface or inside the body is tightly sealed to form a closed environment free from the invasion of bacteria, etc. and then a solution appropriate for cell culture is circulated in the tissue defection thus sealed to thereby regenerate the defective tissue; and a method of administering a drug which comprises dissolving a remedy in the perfusion with the use of the above system and thus promoting the treatment of the defection.Type: GrantFiled: April 17, 2007Date of Patent: November 9, 2010Assignee: New X-National Technology K.K.Inventor: Shigeki Suzuki
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Publication number: 20100280467Abstract: An adhesive patch is provided that allows the user to apply it in a safe and hygienic manner without touching the drug-containing matrix during the sequence of actions from the removal of the liner to the application of the patch. Specifically, the adhesive patch has a multilayer structure that includes a backing, an adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that adheres to the drug-containing matrix surface.Type: ApplicationFiled: April 25, 2006Publication date: November 4, 2010Applicant: Teikoku Seiyaku Co., Ltd.Inventor: Masanori Uematsu
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Patent number: 7825289Abstract: An apparatus for promoting the healing of a wound includes a pressure-sensitive adhesive disposed around a periphery of the wound, and a membrane layer in positioned over the wound with a lower surface in contact with the pressure-sensitive adhesive to form a substantially fluid-tight seal to define reservoir over the wound in which a negative pressure may be maintained. In fluid communication with the reservoir is a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A resilient member is placed over an upper surface of the membrane layer, and a compression member is configured to apply a compressive force to the resilient member. The resilient member distributes the compressive force to the membrane layer to reinforce the fluid tight-seal.Type: GrantFiled: May 16, 2008Date of Patent: November 2, 2010Assignee: Tyco Healthcare Group LPInventor: Mark A. Vess
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Patent number: 7794450Abstract: An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.Type: GrantFiled: October 28, 2004Date of Patent: September 14, 2010Assignee: Smith & Nephew PLCInventors: Patrick Lewis Blott, Bryan Greener, Edward Yerbury Hartwell, Julian Lee-Webb, Derek Nicolini, Clare Green, Robin Paul Martin
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Patent number: 7790946Abstract: A wound dressing apparatus for use in subatmospheric pressure therapy includes an outer member dimensioned for positioning relative to a wound bed and defining an internal reservoir, a port associated with the outer member and in communication with the internal reservoir for applying subatmospheric pressure to the internal reservoir to facilitate treatment of the wound bed and removal of fluid therefrom, an inner member at least partially positionable within the wound bed and confined within the outer member, and an adhesive agent in contact with a peripheral section of the outer member to facilitate attachment of the peripheral section to the periwound tissue. The adhesive agent is preferably substantially devoid of contact with the inner member. In one embodiment, a layer of adhesive material is disposed on the peripheral section of the outer member.Type: GrantFiled: July 6, 2007Date of Patent: September 7, 2010Assignee: Tyco Healthcare Group LPInventor: Sharon Mulligan
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Patent number: 7789869Abstract: A method for detecting and conveying an alarm signal, when an absorbent article is unfastened or, completely removed from the body of the wearer. The method is intended to be used in parallel with a method for detecting wetness in the absorbent article and further relates to an integrated detection-and-alarm method for detecting unfastening and/or wetness in an absorbent article. A system for detecting and conveying an alarm signal when an absorbent article is unfastened or removed from the body of the wearer and/or when the article is wet. The system includes (a) and absorbent article having at least one absorbent layer, the object to be displaced, such as a fastening system, one or more sensoring devices, one or more transmitting devices, and (b) a remote receiver. Furthermore, the system relates to the use of the system in the care of children and adults suffering from incontinence and/or psychological illnesses.Type: GrantFiled: December 21, 2007Date of Patent: September 7, 2010Assignee: SCA Hygiene Products ABInventors: Carolyn Berland, Barbro Moberg-Alehammar
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Publication number: 20100222753Abstract: The invention concerns a patch (1) for application to the skin, comprising: a hydrophilic powder (2) acquiring an adhesive property in the presence of water; a backing (4) having an application side on which the hydrophilic powder (2) is deposited.Type: ApplicationFiled: September 30, 2008Publication date: September 2, 2010Inventors: Bertrand Dupont, Nathalie Donne
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Patent number: 7779625Abstract: A wound therapy device is disclosed. The wound therapy device may include a housing for covering at least a portion of a wound and for sealing to a body surface of a patient. The housing may also include a liquid collector for retaining liquid therein and a vacuum connection for coupling to a vacuum source. The vacuum connection may be in gaseous communication with the liquid collector. The vacuum connection may be separated from the liquid collector by a liquid barrier.Type: GrantFiled: December 13, 2006Date of Patent: August 24, 2010Assignee: Kalypto Medical, Inc.Inventors: Ashok V. Joshi, John Howard Gordon, Sai Bhavaraju, Troy C. Dayton, Jeremy Heiser
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Patent number: 7763455Abstract: The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.Type: GrantFiled: May 13, 2004Date of Patent: July 27, 2010Assignee: Transform Pharmaceuticals, Inc.Inventors: Michael Cima, Wendy Pryce-Lewis, Javier Gonzalez-Zugasti, J. Richard Gyory, Anthony Lemmo, Julie Monagle
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Patent number: 7763000Abstract: A wound treatment apparatus is disclosed to provide vacuum therapy to a wound associated with a patient. The wound treatment apparatus comprises a control unit comprising an alarm and a display displaying an alarm log providing information associated with each activation of the alarm. The display also displays information to instruct a user how to operate the wound treatment apparatus. A method of calibrating the control unit is disclosed.Type: GrantFiled: July 6, 2004Date of Patent: July 27, 2010Inventors: James R. Risk, Jr., Robert Petrosenko
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Patent number: 7759538Abstract: For application of active substances to a wound surface a porous padding (12) is provided upon the wound (10), which is sealingly covered over with a foil (14). A fluid active substance is introduced into the padding (12) via a supply line (22) and is then suctioned out of the padding (12) via a removal line (26). Closure mechanisms (32, 34) control the introduction of the active substance and the suctioning off of the active substance in the manner, that the active substance after being introduced remains for a predetermined dwell time in the padding (12), before it is suctioned off. After the suctioning off the vacuum in the padding (12) is maintained for a certain time period, before renewed introduction of the active substance. The opening of the closure mechanisms (32, 34) are temporally controlled to occur slowly.Type: GrantFiled: July 17, 2006Date of Patent: July 20, 2010Inventor: Wilhelm Fleischmann
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Patent number: 7753894Abstract: An apparatus for cleansing wounds with means for stressing the wound bed and optionally tissue surrounding the wound, in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The means for stressing the wound bed and optionally tissue surrounding the wound promotes wound healing. The dressing and a method of treatment using the apparatus.Type: GrantFiled: December 17, 2007Date of Patent: July 13, 2010Assignee: Smith & Nephew PLCInventors: Patrick Lewis Blott, Edward Yerbury Hartwell, Derek Nicolini, Clare Green, Robin Martin, Bryan Greener, Julian Lee-Webb
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Publication number: 20100174224Abstract: Apparatus is provided for facilitating delivery of a substance through skin of a subject. The apparatus includes a handle and a cartridge, removably coupled to the handle. The cartridge includes one or more electrodes and a patch comprising the substance, the electrodes adapted to be applied to a region of the skin, and the patch adapted to be applied to at least a portion of the region of the skin by removal of the electrodes therefrom.Type: ApplicationFiled: March 10, 2010Publication date: July 8, 2010Applicant: TRANSPHARMA MEDICAL LTD.Inventor: Ze'ev Sohn
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Patent number: 7749204Abstract: The present invention is directed to a method of using a multilayered fabric comprising a first absorbable nonwoven fabric and a second absorbable woven or knitted fabric in tissue repair and regeneration.Type: GrantFiled: October 17, 2005Date of Patent: July 6, 2010Assignee: Ethicon, Inc.Inventors: Sridevi Dhanaraj, Dhanuraj S. Shetty, Hiep Do, Sanyog Manohar Pendharkar
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Patent number: 7745682Abstract: A wound dressing defining skin facing areas having different degrees of skin adherence. The dressing comprises a backing layer defining a center portion and a border portion surrounding the center portion. A carrier layer is secured to the border portion of the backing layer within the border portion and includes a first skin adherent facing layer. An absorbent core is connected to a surface of the backing layer within the center portion and a second skin adherent facing layer is disposed along a surface of the absorbent core. The first facing layer has greater skin adhesive properties than the second facing layer.Type: GrantFiled: July 3, 2008Date of Patent: June 29, 2010Assignee: Ossur hfInventors: Gudmundur Fertram Sigurjonsson, Thordur M. Elefsen, Palmar I. Gudnason
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Publication number: 20100158991Abstract: A patch package structure which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, a peripheral area of the first sheet material having been sealed to a peripheral area of the second sheet material to constitute the package, and a patch disposed in the package; in which the patch includes a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner which protects the pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer, the release liner having a weakening line for assisting a removal of the release liner; and in which the second sheet material has specific first protrudent part, second protrudent part, third protrudent part and elevated part in a central area thereof except the peripheral area thereof.Type: ApplicationFiled: December 22, 2009Publication date: June 24, 2010Applicant: NITTO DENKO CORPORATIONInventors: Katsuhiro OKADA, Yoshihiro IWAO, Kensuke MATSUOKA
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Publication number: 20100152683Abstract: A topical dermal delivery device, such as a patch, for topical delivery of nitric oxide (NO) to treatment sites of mammals is disclosed.Type: ApplicationFiled: March 27, 2008Publication date: June 17, 2010Inventors: Lars Lindgren, Linda Mårlind, Rikard Thorsen
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Patent number: 7732656Abstract: A tissue treatment device has a flexible treatment portion that includes one or more parts and holes arranged in an openwork. A treatment area is defined in the openwork. The treatment portion is deployed such that the treatment area is positioned over tissue to be treated. The openwork minimizes contact between the tissue treatment device and the tissue being treated. A flexible cover is secured against the flexible treatment portion to close the holes and form a treatment volume in the openwork. The minimal contact between the tissue treatment device and the tissue being treated promotes a desired clinical objective.Type: GrantFiled: May 10, 2002Date of Patent: June 8, 2010Assignee: Arizant Healthcare Inc.Inventors: Donald Stapf, Keith J. Leland
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Patent number: 7723560Abstract: A wound vacuum therapy dressing kit is provided for use with a wound drainage system having a vacuum source. The kit may include a wound dressing member, a sealing film, and a wound measurement device. The wound dressing member may include a wound contacting surface configured to be in contact with and generally conform to a wound surface of a patient. The member may be adapted to be coupled to the vacuum source for communicating suction from the vacuum source to the wound surface. The sealing film of the kit may be provided for placement over the member and may be configured to adhere to a patient's healthy skin surrounding the wound. The wound measurement device may include a transparent top portion and a transparent bottom portion configured for placement adjacent the wound surface. The top portion may include a drawing surface and a grid associated with the drawing surface.Type: GrantFiled: December 20, 2002Date of Patent: May 25, 2010Inventors: Jeffrey S. Lockwood, Robert Petrosenko
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Publication number: 20100106107Abstract: A membrane envelope bandage for treating an animal foot or hoof wherein the bandage is generally arcuate in shape and has a membrane envelope affixed to an upper surface of the bandage. The membrane envelope contains a medicine or treatment for applying to the bottom of an animal's hoof or foot. When the bandage is affixed to the bottom of an animal's foot or hoof, the medicine is released from the membrane envelope while the bandage protects the animal's foot or hoof and keeps the medicine from being contaminated.Type: ApplicationFiled: October 22, 2009Publication date: April 29, 2010Inventors: Caroline M. Nash, Tania Woerner