Plural Compartments Or Bags Patents (Class 604/410)
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Patent number: 7727219Abstract: The present invention provides a method for expanding a pre-assembled closed, sterile container system used for the collection, transportation, storage and cryopreservation of biological fluids, such as, blood, bone marrow or umbilical cord blood. The closed sterile bag system comprises a plurality of parts including inlet and or outlet elements and regions for mixing and storing body fluids and cryopreservation liquids, wherein connecting lines provide sterile connection of each component, and wherein the parts are hermetically sealable and separable to maintain sterility system. The methods herein further provide a means for introducing fluids into and/or extracting fluids from a pre-assembled, closed, sterile container system, while maintaining a closed, sterile system without the need to operate under ultra-clean room conditions.Type: GrantFiled: May 26, 2004Date of Patent: June 1, 2010Assignee: Vita 34 AGInventor: Eberhard F. Lampeter
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Patent number: 7722594Abstract: The invention relates to a medical bag which is intended for the infusion of a medicament by means of gravity. The inventive bag comprises: at least two compartments, namely a first compartment (1) containing a medicament in the form of a solution and a second compartment (2) containing a rinsing solution; and means for separating/communicating the compartments, which prevent the rinsing solution from automatically entering the medicament compartment except at the end of the infusion period. The rinsing solution ends the infusion, by rinsing the medicament bag and the infusion line, such as to prevent any risk of contamination or leakage of residual medicament from the bag or line.Type: GrantFiled: June 2, 2005Date of Patent: May 25, 2010Assignee: Laboratoire AguettantInventor: Pierre Frezza
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Patent number: 7708889Abstract: A method used in connection with processing of blood components, wherein blood products are then filtered via a filter rotating along with a centrifuge rotor and the sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products.Type: GrantFiled: January 26, 2009Date of Patent: May 4, 2010Assignee: CaridianBCT, Inc.Inventors: Niclas Högberg, Emanuel Hällgren, Peter Pihlstedt, Brian M. Holmes, Lars Persson, Lars Strandberg, Geert Van Waeg, Frank Corbin, III
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Publication number: 20100100070Abstract: A multi-chamber container of two liquid mixing type, aiming for obtaining an increased reliability for preventing an administration from being practiced under a non separated condition of a weak seal. The medical bag 10 has an outer peripheral strong seal 14 and a weak seal 18 for separating the space inside the medical bag into two partitions 20 and 22. At the tip end of an outlet port 12, a flap 28 as a valve member is provided, which usually closes the outlet port 12 to the space inside the medical bag. The flap 28 is connected to the opposite surface of the medical bag, so that the flap 28 is displaced in cooperation with an expansion deformation of the medical bag as obtained when the weak seal 18 is opened, resulting in opening of the outlet port 12. The flap is formed with a small hole 44 for limiting a liquid flow amount to a small value.Type: ApplicationFiled: October 27, 2009Publication date: April 22, 2010Applicant: AJINOMOTO CO. INC.Inventors: Kaoru SHIMIZU, Yasuhiro Muramatsu
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Patent number: 7686788Abstract: A catheter having a drug delivery unit at the distal end thereof. The drug delivery unit includes an actuator capable of assuming an activated and an inactivated configuration. The drug delivery unit also includes a receptacle capable of accepting a therapeutic agent. The actuator and receptacle are in communication with each other such that the actuator transmits force to the receptacle and the receptacle accepts force from the actuator in an activated configuration of the actuator. Also provided is a method of delivering a therapeutic agent to a target site using the catheter of the present invention.Type: GrantFiled: March 3, 2005Date of Patent: March 30, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Toby Freyman, Maria Palasis, Wendy Naimark, Timothy J. Mickley
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Patent number: 7678097Abstract: A container is provided comprising a body defined, at least in part, by a film, the body including at least one side seal, at least two chambers separated, at least in part, by a peelable seal, and the film including a sealant layer having a bimodal thermal behavior such that the side seal is a permanent seal and the peelable seal can, at least in part, be separated.Type: GrantFiled: November 12, 1999Date of Patent: March 16, 2010Assignee: Baxter International Inc.Inventors: Francesco Peluso, Tranaeus Anders, Dirk Faict, Patrick R. Balteau, Paul-Andre Gollier, Jean-Luc Dewez, Eric J. Henaut, Vincent Houwaert, Philippe Lambert
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Publication number: 20100049158Abstract: A multiple chamber medical fluid bag includes: (i) a flexible enclosure; (ii) a first fluid chamber formed in the enclosure; (iii) a second fluid chamber formed in the enclosure; (iv) the first fluid chamber and the second fluid chamber separated by a frangible seal; and (v) an access port connected to the enclosure, the port imbedded into the enclosure so as to completely surround the access port, the enclosure further configured such that the frangible seal is broken to uncover the access port.Type: ApplicationFiled: August 25, 2009Publication date: February 25, 2010Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.Inventor: Rodolfo Roger
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Patent number: 7648452Abstract: A device for loading a set of bags into the rotor of a centrifuge including a loading container having an annular rim extending outwardly such that the annular rim rests on the turn table of the rotor.Type: GrantFiled: July 3, 2008Date of Patent: January 19, 2010Assignee: CardianBCT, Inc.Inventors: Brian M. Holmes, Johan-Petter Hagström, Per-Olov Lundberg, Geert Van Waeg, Peter Nordgren
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Publication number: 20100010466Abstract: A medical bag having a seal separating its inner space into a plurality of partitions for separate sealed storage of medical liquids and aiming for preventing erroneous operation that an infusion is practiced under a non-opened condition without worsening sterilizing performance during the production of the bag. A weak seal 18 is formed by welding the top and bottom film layers of medical bag 10 along the entire width of the medical bag, so that partitions 20 and 22 are formed at the upper and lower part of the weak seal 18. An outlet port 12 is mounted to the medical bag at a strong seal 14A. The outlet port 12 is extended in the lower chamber 22 to a location adjacent the weak seal 18, so that top end 12A is opened to the lower chamber 22 at a location above the liquid level L.Type: ApplicationFiled: July 30, 2009Publication date: January 14, 2010Applicant: Ajinomoto Co., Inc.Inventor: Yasuhiro MURAMATSU
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Patent number: 7645377Abstract: A system for transferring blood product between a blood storage bag and a processing bag. The system includes an airtight containment chamber for supporting therein one or more blood storage bags. A door is provided for access to the chamber and there is included an airtight fixture that allows tubing from the blood storage bag to exit the chamber. A fluid pump is coupled to the containment chamber for establishing either pressure or vacuum within the containment chamber. A controller controls the air pump to, in turn, control the transfer of a blood product.Type: GrantFiled: January 6, 2006Date of Patent: January 12, 2010Assignee: ZymeQuest, Inc.Inventor: Keith Rosiello
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Publication number: 20090299324Abstract: An environment friendly and inexpensive gas barrier film that allows a medicine to be clearly visible from outside and prevents erroneous administration is provided. A multichamber bag having a diluting solution chamber 3 jointed to one end side of a medicine-accommodation chamber 1 via a weak sealing part 2 and an unoccupied chamber 5 having an opening part 4 jointed to the other end side of the medicine-accommodation chamber 1 via a weak sealing part 2, wherein the medicine-accommodation chamber 1, the diluting solution chamber 3 and the unoccupied chamber 5 are made of a transparent film material and the outside of the medicine-accommodation chamber 1 is covered with a transparent gas barrier film 6, is provided.Type: ApplicationFiled: September 28, 2006Publication date: December 3, 2009Inventors: Fujio Inoue, Isamu Tateishi, Akihito Togawa, Tatsuro Tsuruoka, Masanobu Yoshinaga
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Patent number: 7618406Abstract: A multiple chamber medical fluid bag including: (i) a flexible enclosure; (ii) a first fluid chamber formed in the enclosure; (iii) a second fluid chamber formed in the enclosure; (iv) the first fluid chamber and the second fluid chamber separated by a frangible seal; and (v) an access port connected to the enclosure, the enclosure folded so as to cover the access port and so that the frangible seal is broken to uncover the access port.Type: GrantFiled: January 22, 2007Date of Patent: November 17, 2009Assignees: Baxter International, Inc., Baxter Healthcare S.A.Inventor: Rodolfo Roger
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Patent number: 7618405Abstract: A flexible container incorporating flexible front and rear sheets and one or more container ports disposed in between the sheets are discussed. The one or more container ports each has a pliable attachment flange and an integrally molded nozzle. The pliable attachment flange has a first configuration whereby the attachment flange collapses to enable heat sealing the attachment flange to the sheets and thereafter substantially recovers its shape to provide a fluid pathway with the port. Various terminal ports, terminal caps, and rubber septums may be useable with the one or more container ports.Type: GrantFiled: February 4, 2008Date of Patent: November 17, 2009Assignee: B. Braun Medical Inc.Inventor: Harvey Theodore Young
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Patent number: 7618407Abstract: The invention includes a bag system for collecting a biological fluid, in particular blood. The system includes a device for collecting the fluid which is in fluid communication with at least one fluid collection bag, and a device for sampling the fluid to be collected which includes at least one sampling receptacle. The sampling device includes a device for transferring the fluid from the bag system into the sampling receptacle or receptacles, in which the transfer device is provided with a device for associating the receptacle or receptacles. The transfer device may be arranged to allow the support of the receptacle or receptacles in a standby position, the guidance of the receptacle or receptacles to a transfer position and, after transfer, the dissociation of the receptacle or receptacles from the bag system.Type: GrantFiled: December 10, 2007Date of Patent: November 17, 2009Assignee: MacoPharmaInventors: Sylvie Demay, Francis Goudaliez, Thierry Verpoort
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Patent number: 7618584Abstract: The invention relates to a bag system for the cryopreservation of body fluids, that is blood, bone marrow or umbilical cord blood, the parts of the bag system being sterilized, and separable from one another, wherein liquids which permit and/or assist cryopreservation are located in the bag system and/or may be introduced into the bag system in a sterile form. The bag system, at least, comprising: a device for the direct removal of body fluid (1) from the living body, a region or number of regions for mixing the liquids with the body fluid and/or for storing the mixture of liquids and body fluid, a number of shut-off elements (2) and connecting lines (3) and an inlet element (4) and/or an outlet element (5).Type: GrantFiled: October 16, 2002Date of Patent: November 17, 2009Assignee: Vita 34 AGInventors: Eberhard Lampeter, Dietmar Egger
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Publication number: 20090270859Abstract: A method of performing transurethral surgery on the human or animal body. A tissue is cut using a first active cutting electrode and a second neutral electrode, both electrodes being immersed in an electrically conductive aqueous fluid and connected to a power source for applying a voltage and a current between the electrodes. According to the invention, the electrical conductivity of the fluid is at least 25 mS/cm at room temperature. With the invention, complications of surgery can be significantly reduced.Type: ApplicationFiled: March 19, 2009Publication date: October 29, 2009Inventor: Ari Hirvi
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Patent number: 7601268Abstract: The invention is directed to a system for continuously filtering a blood product including whole blood or any of its component(s), erythrocytes, leukocytes, platelets and plasma either alone or in combination. The system includes a connector for receiving the blood product, a filter coupled to the connector for filtering the received blood product, a collection bag coupled to the filter for collecting the filtered blood product, and a reservoir bag connected to the connector for temporarily storing received blood product, and providing received blood product through the connector to the filter to maintain continuity in filtration. The reservoir bag and the collection bag are suspended, the connector near or below the bottom of the collection bag, and the bottom of the reservoir bag is above the bottom of the collection bag. Also provided is a method of filtering a blood product using the continuous blood filtration system.Type: GrantFiled: May 27, 2003Date of Patent: October 13, 2009Assignee: Haemonetics CorporationInventor: Michael Ragusa
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Patent number: 7597691Abstract: A liquid storage bag having a partition wall allowed to be peeled easily and not peeled by an accidental drop, etc. The liquid storage bag is one wherein the upper part thereof is closed with a freely and closable zipper, the bottom thereof is provided with a liquid outlet, and an easily peelable partition wall (a weak seal part) is provided close to the zipper. The internal space of the liquid storage bag is divided liquid-tightly into upper and lower parts through this weak seal part, liquid is stored in the lower part of the internal space (liquid storage chamber), and the weak seal part is formed in outside-convex form at a center and increased in width at both end parts thereof.Type: GrantFiled: April 23, 2001Date of Patent: October 6, 2009Assignees: Ajinomoto Co., Inc., Nipro CorporationInventors: Yumi Kawaguchi, Toru Ikeda, Yoshihiro Kobayashi, Shozo Taguchi, Yoshikatsu Tomita
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Patent number: 7594908Abstract: Disclosed is a foil pocket (10) comprising at least one carrier foil (11) and at least one lidding foil (12). A foil-type or sheet-type product (1) is enclosed in a gas-tight and moisture-proof manner between the carrier foil (11) and the lidding foil (12), i.e. the joined parts, and is surrounded by a joining zone (30). At least one joining zone section (33, 34, 43, 44) which is not disposed perpendicular to the tear-off peeling direction (9) and is located laterally next to the product (1) widens and/or narrows in the joining zone (30) transversal to the tear-off peeling direction (9). At least the first quarter of the joining zone section (13, 43) that is not disposed perpendicular to the tear-off peeling direction (9) is provided with no widened area (35-41) and/or no narrow area (55-58). The invention make it possible to create a primary packaging which dispenses with the use of auxiliary means such as gloves, tweezers, or similar for applying systems containing active substances.Type: GrantFiled: January 29, 2004Date of Patent: September 29, 2009Assignee: LTS Lohmann Therapie-Systeme AGInventor: Christian von Falkenhausen
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Publication number: 20090192459Abstract: The present disclosure provides for an airless intravenous (IV) bag which contains a specialized device, referred to herein as the airless intravasculature infusion device (AIVID). The AIVID allows one to view the amount of fluid in the IV bag but substantially decreases or completely prohibits the risk of an inadvertent air infusion into a patient.Type: ApplicationFiled: January 9, 2009Publication date: July 30, 2009Inventor: Jeremy Scott CURRY
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Patent number: 7560274Abstract: A culture chamber for use in a method of culturing microbiological material, which comprises a wall or at least a portion of a wall consisting of a gas-permeable membrane, a textured interior growth surface arranged for contact with the microbiological material being cultured and at least a portion of the external surface gas-permeable membrane being textured to enhance gas permeability. Preferably, the gas-permeable membrane is textured over the majority of both of its surfaces. This culture chamber provides enhanced gaseous exchange between the interior and exterior of the culture chamber and increased surface area within the culture chamber for cell attachment.Type: GrantFiled: May 30, 2000Date of Patent: July 14, 2009Assignee: Cellon S.A.Inventors: Jess Paul Fuller, Tony Clayson, Robert MaClean Bird, Timothy Burgess Clifford, Anthony James Knights
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Patent number: 7546918Abstract: The present invention provides a peelable seal for a multi-chambered container including a first edge and a second edge. At least one of the first edge or second edge includes a stress bearing portion and a non-stress bearing portion.Type: GrantFiled: December 19, 2006Date of Patent: June 16, 2009Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Paul Andre Gollier, Patrick Balteau, Vincent Houwaert, Francesco Peluso
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Publication number: 20090131903Abstract: An object of the present device is to provide a cover capable of preventing the administration of unmixed medicaments to a patient. The cover for being mounted on a multi-compartment infusion bag of the present device is a cover for being mounted on a multi-compartment infusion bag including a plurality of compartments partitioned by at least one easily peelable partitioning seal portion which is opened in response to an increase in the internal pressure of at least one of the plurality of compartments induced by pressing said at least one of the plurality of compartments. The cover has a pair of pinch members that pinch at least one of the plurality compartments. The pair of pinch members has engaging elements that engage each other to maintain a pinching state of the pair of pinch members until the pinching state is released in response to an increase in the internal pressure of said at least one of the compartments so that the suspension portion can be used.Type: ApplicationFiled: September 5, 2006Publication date: May 21, 2009Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Hidekatsu Shoji, Kazunari Yoshikawa, Isamu Tateishi
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Patent number: 7530974Abstract: A port closure system for use with a fluid container having fluid ports includes administrative and additive port closure assemblies. The administrative assembly receives a piercing pin and includes an administrative housing which seals closed one fluid port. A sleeve extends from an interior surface past a base surface in the administrative housing. The sleeve has an upper portion and a lower portion, of differing diameters. A cap assembly mates with the administrative housing, sealing the interior surface of the administrative housing. A removable cap provides access to the interior surface. The additive assembly receives a needle and includes a reseal housing which seals closed another fluid port. Another cap assembly mates with the reseal housing, sealing an interior face of the reseal housing. Another removable cap provides access to the interior face. A reseal element is mechanically retained between the reseal housing and cap assembly.Type: GrantFiled: December 21, 2005Date of Patent: May 12, 2009Assignee: Hospira, Inc.Inventors: John Domkowski, Richard E. Burg, Glenn A. Caspary, Joseph Pasini, Stanley F. Pytel, John Sergot
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Publication number: 20090118694Abstract: A fluid supplement bag package has a protective bag having a sealant layer that will not be fused to a fluid supplement bag. The fluid supplement bag can be easily taken out of the protective bag. The fluid supplement bag package includes a fluid supplement bag 2 formed by sealing a fluid supplement in a pouch, and a protective bag 3 sealing up the fluid supplement bag 2 therein. The pouch is formed from a polypropylene film, and the protective bag 3 has an outer layer 4 of a polyester resin, and a sealant layer 7 of a polypropylene resin containing an ultrahigh-molecular-weight polypropylene.Type: ApplicationFiled: March 8, 2007Publication date: May 7, 2009Inventors: Takeshi Inuzuka, Takayuki Kotani
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Patent number: 7503901Abstract: The invention concerns a bag system for collecting a biological fluid the system intended for use in a collection machine including a peristaltic pump, the system including, in closed circuit, a fluid collection device, a solution bag containing an anticoagulant and/or preservation solution, and a collection bag intended to receive the fluid collected with the anticoagulant and/or preservation solution added. The collection bag is in fluid communication with the collection device by way of a first tube provided with a connector and with the solution bag by way of a second tube connected to the connector. A device for associating the first and second tubes is provided to allow, between the connector and the association device, the formation of a loop with the second tube, the conformation of the loop being arranged to enable it to be disposed around at least part of a head of a peristaltic pump.Type: GrantFiled: December 31, 2003Date of Patent: March 17, 2009Assignee: MacoPharmaInventors: Maurice Behague, Francis Goudaliez, Thierry Verpoort
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Patent number: 7497944Abstract: A system and method are used in connection with processing of blood components. The processing of blood components may involve centrifugal separation and/or filtering of the blood components. In some examples, at least some blood components are centrifugally separated in a chamber and then filtered via a filter rotating along with a centrifuge rotor, wherein the filter is located closer than the chamber to an axis of rotation of the rotor. The filter may include a porous filtration medium configured to filter leukocytes, platelets, and/or red blood cells. Some examples include a pressure sensor sensing pressure of pumped blood components. The sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products. Other uses of the sensed pressure are also possible.Type: GrantFiled: March 27, 2007Date of Patent: March 3, 2009Assignee: CaridianBCT, Inc.Inventors: Niclas Högberg, Emanuel Hällgren, Peter Pihlstedt, Brian M. Holmes, Lars Persson, Lars Strandberg, Geert Van Waeg, Frank Corbin, III
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Patent number: 7473238Abstract: A disposable fluid circuit kit for extracorporeal blood treatment systems that supply replacement fluid to a patient is described. The circuit has a blood portion that carries blood and subjects it to some treatment, such as dialysis or hemofiltration. A portion carries filtrate or dialysate. A replacement fluid portion that carries fluid used to compensate for fluid loss is connectable to a supply of replacement fluid. a sterilizing filter in the replacement fluid portion sterilizes the replacement fluid before introduction into the patient acting as a guard against touch contamination of the connected replacement fluid container. Preferably, the filter has a pore size effective to eliminate pyrogens.Type: GrantFiled: August 27, 2003Date of Patent: January 6, 2009Assignee: NxStage Medical, Inc.Inventors: James Brugger, Jeffrey H. Burbank, Dennis Treu
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Publication number: 20080299538Abstract: This invention is directed toward a method of pathogen inactivating whole blood. The steps include collecting whole blood from a donor into a bag; illuminating the whole blood with light at a sufficient energy so that an alloxazine photosensitizer present in the whole blood may be photolyzed to inactivate any pathogens which may be present in the whole blood; and storing the pathogen inactivated whole blood. The invention also includes a method of separating the pathogen inactivated whole blood into components.Type: ApplicationFiled: July 30, 2008Publication date: December 4, 2008Applicant: CARIDIANBCT BIOTECHNOLOGIES, LLCInventors: Raymond P. GOODRICH, Dennis J. HLAVINKA, Heather L. REDDY
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Publication number: 20080300570Abstract: A reconstitution assembly includes: a flexible bag containing a diluent; a drug vial containing a drug; a reconstitution device further comprising: a first sleeve connected to the first container; a second sleeve connected to the second container, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position; a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position.Type: ApplicationFiled: August 12, 2008Publication date: December 4, 2008Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.Inventors: Thomas A. Fowles, Robert J. Weinburg
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Patent number: 7445756Abstract: Apparatus, systems and methods are disclosed for treating a biological fluid with light. A disposable fluid processing set including integrally connected containers and tubing and a holder or organizer for receiving at least some of the containers and tubing are disclosed.Type: GrantFiled: October 11, 2002Date of Patent: November 4, 2008Assignees: Fenwal, Inc., Cerus CorporationInventors: Joseph S. Moore, Daniel Lecour, Yvon Briere, James Laird
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Publication number: 20080255535Abstract: In order to provide a medical liquid container which allows for no forgetful failure to open the partition wall and can realize simple and easy sterilization of the liquid medicament bag and thereby decrease the production cost, the present invention provides a medical liquid container having a plurality of communicatably partitioned medical liquid-housing chambers and a discharge reserve chamber having formed therein a discharge port for a liquid medicament, the medical liquid container comprising liquidtightly partitioning portion for liquidtightly separating said liquid medicament-housing chambers from each other, and non-liquidtightly partitioning portion for non-liquidtightly separating between at least one of said liquid medicament-housing chambers and said discharge reserve chamber.Type: ApplicationFiled: May 31, 2005Publication date: October 16, 2008Inventor: Katsuyuki Yoshikawa
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Publication number: 20080234652Abstract: A freeze-dried material is stored in a first chamber of a container along with a reconstituting liquid for the freeze-dried material, which is stored in a second chamber of the container. A sealing wall within the container forms a barrier between the first chamber and the second chamber preventing contact between the freeze-dried material and the reconstituting liquid. At least one valve assembly in the sealing wall selectively opens a region of the sealing wall to establish fluid flow communication between the first and second chambers, allowing the freeze dried material to be reconstituted. The reconstituted freeze-dried material can be administered from the same container to a recipient.Type: ApplicationFiled: March 19, 2007Publication date: September 25, 2008Inventors: Simon J. McCarthy, John W. Morgan, William D. Block
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Patent number: 7425207Abstract: A vial for dispensing a liquid into a syringe is described which comprises a body section for holding the liquid, the body section having a top and a bottom; a port having a removable seal, where the port is adapted for a syringe connection and where the port is interconnected with the body section at a point near the top of the body section by a passageway which for at least a portion of its length extends above the level of the liquid in the body section when the vial is inverted, thereby preventing leakage of the liquid from the body section when the seal of the port is removed. A method of making the vial is also described.Type: GrantFiled: June 13, 2005Date of Patent: September 16, 2008Assignee: Holopack International Corp.Inventors: Shawn W. Miller, David Rocheleau, Mohammad R. Sadeghi, Walter Zahn, Bernd Hansen
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Patent number: 7413665Abstract: A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.Type: GrantFiled: December 15, 2006Date of Patent: August 19, 2008Assignee: Gambro BCT, Inc.Inventors: Brian M. Holmes, Johan-Petter Hagström, Per-Olov Lundberg, Geert Van Waeg, Peter Nordgren
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Publication number: 20080177243Abstract: A multiple chamber medical fluid bag including: (i) a flexible enclosure; (ii) a first fluid chamber formed in the enclosure; (iii) a second fluid chamber formed in the enclosure; (iv) the first fluid chamber and the second fluid chamber separated by a frangible seal; and (v) an access port connected to the enclosure, the enclosure folded so as to cover the access port and so that the frangible seal is broken to uncover the access port.Type: ApplicationFiled: January 22, 2007Publication date: July 24, 2008Applicant: Baxter International Inc.Inventor: Rodolfo Roger
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Patent number: 7396451Abstract: A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.Type: GrantFiled: December 15, 2006Date of Patent: July 8, 2008Assignee: Gambo BCI, Inc.Inventors: Brian M. Holmes, Johan-Petter Hagström, Per-Olov Lundberg, Geert Van Waeg, Peter Nordgren
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Patent number: 7384416Abstract: A biological fluid collection system including a collecting device, a collecting container, a first channel connecting the two, a sampling bag, a second channel connecting the sampling bag and the first tube and at least one substantially irreversible closure device in an open position on at least the first or second channel. The biological fluid may be blood. A method of collecting biological fluid such as blood using the system so that fluid in the sampling bag is substantially irreversibly prevented from entering the collecting container.Type: GrantFiled: August 12, 2002Date of Patent: June 10, 2008Assignee: MacopharmaInventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7374870Abstract: Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.Type: GrantFiled: February 11, 2005Date of Patent: May 20, 2008Assignee: Fenwal, Inc.Inventors: Robert E. Herman, John Chapman, Chong-Son Sun, Jean M Mathias, Daniel F. Bischof
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Patent number: 7354426Abstract: A flexible container incorporating flexible front and rear sheets and one or more container ports disposed in between the sheets are discussed. The one or more container ports each has a pliable attachment flange and an integrally molded nozzle. The pliable attachment flange has a first configuration whereby the attachment flange collapses to enable heat sealing the attachment flange to the sheets and thereafter substantially recovers its shape to provide a fluid pathway with the port. Various terminal ports. terminal caps. and rubber septums may be useable with the one or more container ports.Type: GrantFiled: September 12, 2003Date of Patent: April 8, 2008Assignee: B. Braun Medical Inc.Inventor: Harvey Theodore Young
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Patent number: 7351344Abstract: The invention relates to a sterile system and a method for filtering biological or medical liquids, especially blood or blood constituents. According to the filtering system and method, the sterile air already in the system is collected before the beginning of the filtration process, and after the filtration process, in order to completely empty the system used. Said filtering system comprises a collapsible container having a first and second air inlet/outlet line. The first air inlet/outlet line communicates with the first chamber of the filter by means of a flow connection, and the second air inlet/outlet line with the second chamber of the filter. Only the air inlet/outlet line communicating with the first filter chamber is sealed by a hydrophobic membrane or a return valve in the filtering system, such that the system has an especially simple structure.Type: GrantFiled: January 9, 2003Date of Patent: April 1, 2008Assignee: Fresenius Hemocare Italia S.R.L.Inventors: Paolo Verri, Giorgio Mari
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Patent number: 7347913Abstract: Apparatus (20) and methods for segmenting a blood-filled tube (42) into multiple, blood-containing, sealed segment are disclosed. The apparatus (20) includes a tubing locating surface (22) for mounting the tubing and sealing means (24) cooperatively associated with the tubing locating surface (22).Type: GrantFiled: April 9, 2002Date of Patent: March 25, 2008Assignee: Fenwal, Inc.Inventor: Joseph Dallapiazza
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Patent number: 7345029Abstract: The present invention relates to a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. The avoidance of a glucose-like degradation as well as hydrolysis during sterilization and storage while maintaining a neutral mixture pH is achieved according to the invention by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further relates to a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.Type: GrantFiled: April 18, 2003Date of Patent: March 18, 2008Assignee: Fresenius Medical Care Deutschland GmbHInventor: Thomas Zimmeck
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Patent number: 7329240Abstract: A protective package for a medicament dispenser has an inner protective layer and an outer chemical barrier layer. The protective package also includes at least one reinforcing layer secured to the outer chemical barrier layer. At least one light inhibiting layer is further provided to limit the transmission of light through the package.Type: GrantFiled: December 19, 2003Date of Patent: February 12, 2008Assignee: Meridian Medical Technologies, Inc.Inventors: C Michael Mesa, Daniel Jendrycki, Cynthia J. Good
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Patent number: 7326194Abstract: A fluid ducting assembly for enabling flow communication between a syringe and either one of a vessel and a dispenser for dispensing a fluid contained, a priori in the syringe or in the vessel. The fluid ducting assembly includes a base having a first member, a second member, and a third member for connection to and providing flow communication with the syringe, the vessel and the dispenser, respectively. The fluid ducting assembly further includes a flow controller within the base enabling any one of a flow path between the first member and the second member and a flow path between the first member and the third member. The flow controller has either a first operative position in which the flow path between the first member and the second member is enabled or a second operative position in which the flow path between the first member and the third member is enabled.Type: GrantFiled: January 31, 2002Date of Patent: February 5, 2008Assignee: Medimop Medical Projects Ltd.Inventors: Freddy Zinger, Igor Denenburg
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Patent number: 7318819Abstract: An automatic locking valve for safely administering a dose of medication is disclosed. The automatic locking valve comprises a valve housing defined with a space and formed with input and output ports for intaking and discharging the medication, a spool-shaped on/off member having a diameter smallest at the center thereof and being tapered to linearly increase toward upper and lower portions of the on/off member so that the on/off member moves up and down depending on a closed state of the door, and a membrane attached to the space of the valve housing such that the membrane expands toward a lower portion of the space due to an elasticity of the membrane when the tube is blocked. The medication can be safely and accurately administered under a condition of installation with the door closed above the tube.Type: GrantFiled: August 5, 2004Date of Patent: January 15, 2008Assignee: Woo Young Medical Co., LtdInventors: Young Gyu Lee, Ki Woon Kim
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Patent number: 7306583Abstract: A bag system for the collection and sampling of a biological fluid such as blood is described. The system may include a fluid collection bag and a first tube connected on one end to a collection means and on the other end to the collecting bag. It may also include a flexible sampling bag defining an internal volume having a bottom side and an introduction side which is opposite to the bottom and has an inlet orifice. The system also has a second tube, a first end part of which is connected to the first tube and a second end part of which is inserted in the inlet orifice of the sampling bag, so as to extend inside the sampling bag over a distance of between 25% and 60% of the distance between the bottom and the introduction side of the internal volume of the sampling bag.Type: GrantFiled: June 17, 2004Date of Patent: December 11, 2007Assignee: MacoPharmaInventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7306095Abstract: A polymeric film, multiple-compartment, pouch having an internal frangible seal for confining a fluid and related beverage container with a re-closable fitment for storing and delivering two different flavored liquids or the like. The frangible seal of the clear plastic pouch will burst when sustained squeezed thus allowing the flavors to swirl and mix within the pouch.Type: GrantFiled: January 27, 2006Date of Patent: December 11, 2007Assignees: E. I. du Pont de Nemours and Company, Ocean Spray Cranberries, Inc., Kornick LindsayInventors: Raymond Anthony Bourque, Daniel Young-Doo Chung, Richard M. Estabrook, Diane McCauley Hahm, James L. Henderson, Joseph Kornick, I-Hwa Lee, Jose Tirso Olivares-Cordoba, Donna Lynn Visioli, James P. Kane, Jr.
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Patent number: 7294122Abstract: A transfer needle comprises: a liquid-specific member; and a medicament-specific member to be separably connected or joined to the liquid-specific member in a liquid-tight state. The liquid-specific member comprises: a liquid-specific hollow needle projecting toward the opposite side from the medicament-specific member. The medicament-specific member comprises: a medicament-specific hollow needle projecting toward the opposite side from the liquid-specific member and communicating with the liquid-specific hollow needle. A female luer is provided on at least one of the liquid-specific member and the medicament-specific member at a position opposing to the other. The female luer communicates with the one hollow needle and is separably connected with an injection needle connecting portion of a syringe in a liquid-tight state.Type: GrantFiled: July 16, 2004Date of Patent: November 13, 2007Assignee: NIPRO CorporationInventors: Tomohiko Kubo, Shuji Hasegawa, Yoshiyuki Sunaga, Takao Kinoshita
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Patent number: 7288082Abstract: A method and apparatus are provided by which a fluid may be drawn and packaged within a series of interconnected sterile units. Once filled with the fluid, the connectors joining the sterile units may be sealed and severed to produce a number of separate sterile units. The volume of the separate sterile units may correspond to a single dose of the fluid. The technique allows a fluid to be partitioned into sterile units without exposure to the air or other potential contaminants.Type: GrantFiled: October 17, 2002Date of Patent: October 30, 2007Assignee: SeeFit IncorporatedInventor: Richard W. Yee