Materials Mixed Within Container Patents (Class 604/416)
  • Patent number: 10716548
    Abstract: The invention relates to syringes for storing and mixing components.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: July 21, 2020
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Yair Pilpel, Sivan Doron, Yuri Zherdev, Lior Erez, Ashley DeAnglis
  • Patent number: 10585021
    Abstract: Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: March 10, 2020
    Assignee: Instrumentation Laboratory Company
    Inventors: Gert Blankenstein, Hansong Zeng
  • Patent number: 10537692
    Abstract: A unit dose container for the containment of an intranasal formulation for use with the POD device.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: January 21, 2020
    Assignee: Impel Neuropharma, Inc.
    Inventors: John D. Hoekman, Alan Brunelle, Craig Kohring, Christopher Fuller
  • Patent number: 10442583
    Abstract: A process for the production of a device for dispensing eye drops. The process includes the steps of providing a first container and a second container configured to be engaged in a fluid-tight manner, providing a spacer, introducing a water-based solution inside the first container, introducing a solution or dispersion comprising a drug inside the second container, arranging the spacer between the first and second containers, engaging in a fluid-tight manner the second container and the first container, and freeze-drying the solution or dispersion comprising the drug.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: October 15, 2019
    Assignee: DOMPE' FARMACEUTICI S.P.A.
    Inventor: Marco Maria Gentile
  • Patent number: 10433825
    Abstract: Provided herein are systems for preparing and delivering fibrin sealant to a surface and methods of use thereof. In one embodiment, the system comprises: a. a quantity of a liquid mixture disposed within a container, the mixture comprising: I. fibrin or II. fibrinogen and Factor II; and b. a resin bed disposed within a vessel, the vessel capable of being in fluid communication with the container, wherein when in fluid communication, passage of the mixture through the vessel results in modification of the concentration of small molecules inhibitor(s) and/or inducer(s) within the mixture, favoring fibrin clot formation.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: October 8, 2019
    Assignees: Ethicon, Inc., Omrix Biopharmaceuticals Ltd.
    Inventors: Ashley DeAnglis, Yair Pilpel, Yuri Zherdev, Sivan Doron, Lior Erez
  • Patent number: 10350364
    Abstract: A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a valve between a first and second chamber that are slidably movable relative to each other and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: July 16, 2019
    Assignee: Windgap Medical, Inc.
    Inventors: Adam R. Standley, Christopher J. Stepanian, Brent R. Buchine, Michel Bruehwiler, Cole Constantineau, Jeffrey Thomas Chagnon, Robert Brik
  • Patent number: 10155183
    Abstract: Embodiments of the present invention relate to a filtration device and method for filtering liquids. In conventional devices, a liquid is placed in a vial, and a plunger, having a filter membrane located at one end, is depressed into the vial, causing the liquid to pass through the filter membrane into the interior of the plunger, where it is stored until required for further processing. However, such plungers are typically made of a plastics material. It is undesirable to store the filtered liquid in contact with plastics for extended periods of time, as contaminants may leach from the plastics material into the sample. In embodiments of the present invention, a filtrate receptacle made from a different material to the plunger, such as a glass material, is located in the interior of the plunger and the filtered liquid collected in the filtrate receptacle after passing through the filter membrane.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: December 18, 2018
    Assignee: GE HEALTHCARE UK LIMITED
    Inventors: Stevan Paul Tortorella, Navin Deepal Pathirana, Geraint Seymour
  • Patent number: 10099012
    Abstract: Disclosed are a closure system for an applicator attachment on a container for pharmaceutical preparations and to a use of the closure system, a syringe for medical purposes, including a container for pharmaceutical preparations and a closure system, and a method of assembling a syringe. The aforementioned operate such that splash prevention and a venting function are integrated in the closure system.
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: October 16, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Friedrich Haefele, Markus Hemminger, Tobias Sachsse, Klaus Boje
  • Patent number: 9642774
    Abstract: Liquid container with a predetermined break point (4), which is covered by an elastomer septum (3). The container forms a hollow body (10) made of a single material that is compatible with critical liquids such as medicines. The elastomer septum (3) and the predetermined break point (4) can be pierced by a hollow needle (51) in order to withdraw liquid from the container.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: May 9, 2017
    Assignee: Stryker European Holdings I, LLC
    Inventor: Christoph Helmut Sattig
  • Patent number: 9216175
    Abstract: The invention provides sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof. The invention further provides sublingual formulations containing buprenorphine and naloxone, pharmaceutically acceptable salts thereof or derivatives thereof. The invention further provides a method of treating pain or opioid dependence by administering sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof to a patient in need thereof.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: December 22, 2015
    Assignee: Insys Pharma, Inc.
    Inventors: Kiran P. Amancha, Chandeshwari S. Chilampalli, Venkat R. Goskonda
  • Patent number: 9039673
    Abstract: A withdrawal spike unit (200) comprises a withdrawal spike component (30?) and an integrally formed adapter component (60?) that is adapted to couple with a vial (10) in a safe and secure manner. The integral formation of the component parts (30?, 60?) makes fully automated manufacture and assembly of assemblies comprising such a withdrawal spike unit (200) coupled to a vial (10) possible. As such, human errors associated with the assembly at the point of use are mitigated.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: May 26, 2015
    Assignee: Novartis AG
    Inventors: Dietmar Weitzel, Astrid Hoffmann
  • Patent number: 9039672
    Abstract: A coupling component is disclosed for transmitting medical substances, comprising two channels for conveyance of medical substances in two substantially opposite directions and a means for releasable connection to a second coupling component having a further channel for creating a coupling. The connecting means is a thread. A method for conveying medical substances to and from a container is also disclosed.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: May 26, 2015
    Assignee: Carmel Pharma AB
    Inventor: Claes Wallen
  • Publication number: 20150141913
    Abstract: An apparatus comprises a plunger able to fit in a cartridge or syringe. The plunger includes an outer portion and a deflection portion. The outer portion is able to engage the body of the cartridge or syringe. The outer portion is operable to apply a first radial force to the cartridge or syringe. The deflection portion is positioned within the outer portion and is movable between a locked position and an unlocked position. The deflection portion in the unlocked position causes the outer portion to apply a second radial force to the cartridge or syringe.
    Type: Application
    Filed: June 26, 2013
    Publication date: May 21, 2015
    Inventors: Rush L. Bartlett, II, Peter M. Greco, JR., Barry J. Davignon
  • Patent number: 9022653
    Abstract: The present invention refers to a flexible multiple chamber bag comprising: a) three adjacent chambers, a first chamber partially separating a second upper chamber from a third lower chamber by first and second welded seams, b) said second chamber and said third chamber being partially connected by a third welded seam, c) said first welded seam being non-peelable and said second and third welded seams being peelable said second and third welded seams having the shape of an inverse letter “V” each second and third welded seam starting at the basic point of said “V” and terminating essentially in a right angle at the circumference weld of said bag, said bag comprising a hanger flap extending from the top end of said bag and a medical port welded to the lower end of said circumferential weld.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: May 5, 2015
    Assignee: B. Braun Melsungen AG
    Inventors: Michel Pittet, Caroline Ansermet, Bastien Ecabert, Cedric Berchier
  • Patent number: 9011408
    Abstract: Delivering a blood processing solution to blood in a blood bag includes coupling a first tube to a vented spike at one end and to a Y-shaped tube connector at a second end. An in-line microbiotic barrier filter is coupled to the first tube between its ends. A second tube is coupled to a transfer bag at one end and to the Y-shaped tube connector at its other end. A third tube is coupled to the output of the Y-shaped tube connector and sealed at its distal end. The blood bag includes a fourth tube that is sealed at a distal end. The third tube is welded to the fourth tube using a sterile tubing welder, wherein a functionally-closed, sterile flow path through which the blood processing solution can flow into the blood bag is maintained.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: April 21, 2015
    Assignee: Biomet Biologics, LLC
    Inventor: Alan Gray
  • Patent number: 9005181
    Abstract: A connector for providing sterile access to a flexible container is provided that comprises a tubular member having a first portion and a second portion, each of the first portion and the second portion having an open end. The first portion and second portion are joined to each other by a frangible segment, with each of the first portion and the second portion having a gripable surface associated therewith that is configured to facilitate the application of torsional force to the tubular member at the frangible segment. Upon the application of a sufficient amount of torsional force, the frangible segment will break, permitting the first and second portions to be separated from each other.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: April 14, 2015
    Assignee: Fenwal, Inc.
    Inventors: Daniel Lynn, Richard L. West, Bryan Blickhan, Phoung Tran, Shawn Davis
  • Patent number: 8992490
    Abstract: The invention relates to a drip chamber for an infusion device and an infusion device having such a drip chamber, by means of which medical solutions can be fed to a patient, such as infusion solutions for chemotherapy. The drip chamber (1) according to the invention is provided for connecting to a fastener (8) of an infusion container (2), comprising a withdrawal part (25) for withdrawing fluid, having an opening (28) closed by a penetrable membrane (27) and an injection part (26) for injecting a fluid, having an opening (30) closed by a penetrable membrane (29). The connecting part (7) and/or piercing spike (11) of the drip chamber (1) according to the invention is designed such that a snap-fit or latching connection to the injection part (13) and/or the withdrawing part (25) of the fastener (8) of the infusion container (2) can be produced when the connecting part (7) of the drip chamber (1) is connected to the fastener (8) of the infusion container (2).
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: March 31, 2015
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Torsten Brandenburger, Ismael Rahimy
  • Patent number: 8973622
    Abstract: Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to a at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: March 10, 2015
    Assignee: ICU Medical, Inc.
    Inventors: George A. Lopez, Thomas F. Fangrow, Peter Leissling, Matthias Janssen
  • Patent number: 8939326
    Abstract: The present invention proposes a dispensing container (1) A for probiotics (2) in a viscous or liquid carrier (3), the probiotics (2) having a higher specific weight than the viscous or liquid carrier (3), wherein the container (1) comprises a reservoir (4) for holding the carrier (3) and a dispensing head (5) being in fluid connection with the reservoir (4), the dispensing head (5) comprising at least one outlet (6), wherein the concentration of the probiotics (2) decreases from the outlet (6) of the dispensing head (5) towards a bottom portion (1a) of the reservoir (1).
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: January 27, 2015
    Assignee: Nestec S.A.
    Inventor: Karl-Josef Huber-Haag
  • Patent number: 8926583
    Abstract: The present invention concerns a male connection part for connection with a female piercing member protection device having a longitudinal cylinder-like body having a longitudinal axis C, a first side and a second side, an outer and an inner surface, a barrier member arranged at the center of the first side of the male connection member, intersecting the longitudinal axis C, and a fluid communication channel extending from the barrier member of the male connection part to the second side of the male connection part, wherein the male connection part further comprises at least one turning grip protrusion to provide for an increased turning friction between the female piercing member protection device after assembly.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: January 6, 2015
    Assignee: Carmel Pharma AB
    Inventors: Anna Ellstrom, Tobias Rosenquist
  • Publication number: 20140378937
    Abstract: A dispensing assembly includes a syringe body having a barrel and a dispensing tip. The dispensing assembly further includes a mixing and plunging assembly configured for coupling with the syringe body and comprising a mixer and a plunger. The mixer is configured for mixing material in the barrel and has a rod and a mixing element removably connected with the rod. The plunger is configured to dispense material from the barrel through the dispensing tip. Also, the rod is configured to be detached from the mixing element and used to push material out of the dispensing tip.
    Type: Application
    Filed: June 23, 2014
    Publication date: December 25, 2014
    Inventors: Benjamin B. Anderson, Kevin C. Geppert, Jon E. Hoogenakker, Huadong Lou, Zachary Rzeszutek, Mark Stevenson
  • Patent number: 8911421
    Abstract: A system for mixing the contents of a first container and a second container. The system includes the first container that has container body with an opening fluidly connected to a cavity defined by the container body, a first substance contained in the cavity, and a stopper sealing the opening. The second container includes a port assembly including a port housing connected to the second container and a retainer constructed to connect to the first container. The retainer is configured to rotate and move axially relative to the port housing, wherein relative rotation between the port housing and the retainer causes the retainer to move axially relative to the port housing. The port assembly further includes an axially fixed actuator constructed to force the stopper into the first container when the retainer is rotated relative to the port housing.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: December 16, 2014
    Assignee: Hospira, Inc.
    Inventors: John A. Domkowski, David L. Foshee, Theodore J. Mosler, Edward Browka
  • Patent number: 8911420
    Abstract: A device (1) for the containment of platelet concentrates includes at least a bag (2) defining at least a containment chamber (3) having at least a mouth (4) for the entry of a platelet concentrate and at least a connection element for connection to an infusion line associated with the bag in correspondence to the mouth; the connection element includes a first and a second portion (5a, 5b) integrally associated together and includes at least a constantly open duct (6), passing through the first and the second portion and communicating with the chamber, where the first portion is associable with the infusion line and the second portion is associated with the bag in correspondence to the mouth, the first portion being separable from the second portion in such a way to interrupt the duct and define an opening (8) accessible from outside and including closing element (9) of the opening.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: December 16, 2014
    Assignee: Biomed Device S.R.L.
    Inventor: Marco Bertoni
  • Patent number: 8910832
    Abstract: Device for the preservation of substances to be kept separate until their application includes a container (2), which is provided with an at least partially deformable body (6), and a delivery mouth (4), on which there is provided a delivery element for delivering the mixture. A watertight chamber (5) is arranged between the delivery mouth and the body of the container and is provided with a connection mouth (12) for the connection to the body (6), which is closed by cap means (20). A component of the substance to be delivered is contained in the watertight chamber (5), whereas another component is contained in the body (6). The communication between the two components is established by removing said cap, by interference between the walls of the cap and the walls of the body.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: December 16, 2014
    Assignee: Inge S.p.A.
    Inventor: Alessio Nobbio
  • Patent number: 8905994
    Abstract: Valve assemblies for use with a liquid container and a drug vial for enabling an initial transfer of liquid contents from the liquid container to the drug vial for liquid drug formation purposes and subsequent transfer of liquid drug contents from the drug vial to the liquid container for administration purposes. Liquid drug transfer sets can include a valve assembly pre-attached to a liquid container. Alternatively, liquid drug transfer sets can include a valve assembly packaged in sterile blister packaging ready for attachment to a liquid container prior to use.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: December 9, 2014
    Assignee: MEDIMOP Medical Projects, Ltd.
    Inventors: Nimrod Lev, Niv Ben Shalom
  • Patent number: 8894627
    Abstract: A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: November 25, 2014
    Assignee: J & J Solutions, Inc.
    Inventors: Jared Garfield, John Slump, Gregory Lyon
  • Patent number: 8882739
    Abstract: A port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a port housing for connection to a second container, and a retainer for connection to a first container, wherein the retainer rotates relative to the port housing and is constructed to move axially within the port housing. An actuator is axially fixed within the port housing and forces a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing. The assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: November 11, 2014
    Assignee: Hospira, Inc.
    Inventors: John A. Domkowski, John Sundquist, Benjamin Leo Rush, David L. Foshee, Theodore J. Mosler, Edward Browka
  • Patent number: 8882736
    Abstract: A container for re-suspending sedimented medicament comprises a reservoir for containing a suspension of particles in a liquid, a dispensing portion, and a sealing portion. The sealing portion is arranged to be in fluid communication with the reservoir via an orifice. The orifice is positioned between the dispensing portion and the sealing portion, and allows a turbulent flow of the liquid from the reservoir into the sealing portion to enable re-suspension of particles that have sedimented out of the liquid in the sealing portion.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: November 11, 2014
    Assignee: Norton Healthcare Limited
    Inventor: Martin Oliver
  • Patent number: 8882737
    Abstract: A self standing bag having two side wall sheets and a bottom sheet. To flatten the bag, the bottom sheet is sandwiched between the two side wall sheets and symmetrically folded along a line parallel to its bottom edge, separating the bag into a four-layer part and a two-layer part. In the two-layer part, the bag includes first sloped sealing lines extending between a first two points on the top edges of the side wall sheets and spaced from the vertical side wall edges by a first distance, to a second two points spaced from the vertical edges of the side wall sheets by a second distance less than the first distance. The four-layer part includes second sloped sealing lines extending between the second two points and a third two points on the bottom edges of the side wall sheets.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: November 11, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Thomas Graf, Paul Gastauer, Philippe Laffay, Francois Dumont D'Ayot, Pascal Lengrand, Bertrand Thibault
  • Patent number: 8883762
    Abstract: The present invention provides a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. Glucose-like degradation and hydrolysis is avoided during sterilization and storage, while maintenance of a neutral mixture pH is achieved by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further discloses a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: November 11, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Thomas Zimmeck
  • Patent number: 8876790
    Abstract: A connector according to the invention includes a first connection region for connecting a first container, a piercing element and a break-open element, wherein the piercing element has a first end section and a second end section and a channel, running from the first end section to the second end section, for transporting a medicinal active substance, wherein the first end section is formed for piercing a membrane of the first container connected in the first connection region, and, at the second end section, the break-open element is attached such that it can be broken open and/or broken off, wherein, in the attached state, the break-open element seals the channel of the piercing element in liquid tight fashion.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: November 4, 2014
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Ismael Rahimy, Torsten Brandenburger
  • Patent number: 8864737
    Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: October 21, 2014
    Assignee: Nipro Corporation
    Inventors: Mitsuru Hasegawa, Atsushi Ishikawa, Suguru Oyagi, Takeshi Ohguro
  • Patent number: 8834444
    Abstract: A system for mixing contents of a first container with contents of a second container. The system includes a first container, a second container, a device for establishing fluid communication between the first container and the second container, and a hanger for hanging the system, wherein the hanger is operable only when fluid communication between the first container and the second container has been established. The system can be used in a method for preventing medication delivery errors.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: September 16, 2014
    Assignee: Hospira, Inc.
    Inventor: John A. Domkowski
  • Patent number: 8807177
    Abstract: An automated syringe filler is disclosed comprising a housing and motor with a rotatable syringe holder plate that can be raised and lowered onto exposed syringe needles. The housing also has components for one or more syringes to be attached with the needles pointing upward and the syringe plungers moveably positioned at the bottom. The syringe plunger tool controls the movement of the syringe plunger and can be horizontally and vertically positionable. The syringe plunger tool is motorized and can be controlled by a CPU or similar device containing programmable media.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: August 19, 2014
    Inventor: Saverio Roberto Strangis
  • Patent number: 8802362
    Abstract: Methods and devices for preparing a solid-fibrin web are provided. One method may include drawing blood from a patient, separating plasma from the blood, contacting the plasma with a calcium-coagulation activator and concurrently coagulating and axially centrifuging the plasma to form the solid-fibrin web. The solid-fibrin web may be suitable for regenerating body tissue in a living organism. Devices used in the methods may also be provided.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: August 12, 2014
    Assignee: Cascade Medical Enterprises, LLC
    Inventors: Nicholas A. Grippi, Roberto C. Beretta
  • Patent number: 8801688
    Abstract: The invention comprises a novel apparatus for delivering a nutritive substance comprising a container body having a base at one end thereof, an upper portion adapted for removable receipt of a closure, the upper portion defining an opening therein, and a chamber defined by the container body, the chamber being in fluid communication with the upper portion opening. A seal is bonded across the upper portion opening of the container and is adapted to provide an airtight seal across the opening. A closure is removably coupled to the container upper portion. A nutritive substance is coated onto an element selected from the group consisting of an inner surface of the container upper portion, the closure, an insert positioned above the seal, and combinations thereof. The seal prevents contact between the nutritive substance and the contents of the container until the seal is removed or pierced.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: August 12, 2014
    Assignee: Mead Johnson Nutrition Company
    Inventors: Robin P. Wiggins, Rick Grelewicz, Nagendra Rangavajla, Joshua C. Anthony, Patrick McCallister
  • Patent number: 8801689
    Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: August 12, 2014
    Assignee: Hospira, Inc.
    Inventors: Yei F. Moy, Stanley F. Pytel, John S. Ziegler, Jesse C. Darley, Douglas S. Rodenkirch
  • Patent number: 8790327
    Abstract: A first connector is provided and includes a first connector body having a cylindrical outer tube, a cylindrical inner tube, and a hub; a hollow needle supported by the hub; a first sealing member supported by the inner tube; a coil spring that biases the hub in a proximal direction and biases the first sealing member in the distal direction; and gripping and pressing members disposed on the outer tube. A plurality of pawls are formed on a flange of the hub. A plurality of ratchet teeth are formed on an inner circumferential portion of a proximal portion of the outer tube. Each of the ratchet teeth and each of the pawls of the hub form an engagement-disengagement mechanism.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: July 29, 2014
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Masafumi Takemoto
  • Patent number: 8763798
    Abstract: The present invention relates to a closure for filling and sealing receptacles containing medicinal fluids, a method for filling a receptacle with a medicinal fluid and sealing the receptacle. The closure used in the method comprises a mounting piece that may be attached to the receptacle and a connector piece that may be connected to a connector piece of a filling device. A closure body is arranged between the mounting piece and the connector piece, in which a closure piece for sealing the closure sits. The closure piece may be slid between a position sealing the closure and a position which opens the closure. The closure is sealed tight with a removable protective cap. The present method is characterized in that with the protective cap removed the receptacle is filled through the closure in a clean room, whereupon after filling, the closure is sealed by pressing the closure piece into the closure.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: July 1, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Michael Paul
  • Patent number: 8758322
    Abstract: A dispensing insert is configured to friction fit within a neck of a bottle and to selectively receive an oral syringe. The dispensing insert includes a hollow cylinder, a top plate capping one end of the hollow cylinder, a raised deck extending substantially parallel to and spaced from the top plate, and an annular side wall extending from the top plate upwardly toward the raised deck. The raised deck has a smaller outer diameter than the top plate and defines an opening therethrough configured to provide access to contents of the pharmacy bottle through the dispensing insert. The annular sidewall substantially encompasses an outer perimeter of the raised deck.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: June 24, 2014
    Assignee: Target Brands, Inc.
    Inventors: Ryan P. McCoy, Stacy Abel, Matthew P. Franks, Gordon Beecroft, John Vassallo, Michael Makhlouf
  • Patent number: 8753670
    Abstract: A fibrin wound dressing is made by mixing quantities of fibrinogen solution and thrombin solution with air. The resulting foam is very light weight, and with the proper attention to the amount of thrombin, is also sufficiently viscous to rest on a vertical surface without dripping. The wound dressing may also be formulated for its ability to continue migration of healing substances, such as PDGF, from the dressing to the wound site. Thrombin substitutes, such as other clotting proteins, may be used instead of thrombin. The resulting foam may also be lyophilized or ground and lyophilized for later reconstitution. A therapeutic drug or other additive may also be added to the wound dressing.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: June 17, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: Yves A. Delmotte
  • Publication number: 20140163475
    Abstract: A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
    Type: Application
    Filed: March 18, 2013
    Publication date: June 12, 2014
    Applicant: MEDRAD, INC.
    Inventors: Arthur E. Uber, III, Mark Trocki, Frederick W. Trombley, III, Kevin P. Cowan
  • Patent number: 8721616
    Abstract: The invention refers to a new system for packaging pharmaceutical compositions comprising active principles that may be administered intravenously, in particular it concerns a system for packaging in bottles which makes it possible to ensure the complete transfer of the content of the bottle into the liquid for intravenous infusion and at the same time prevent any accidental contact with the active principle by the health-care personnel preparing said intravenous infusion, and a complete kit for intravenous administration.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: May 13, 2014
    Assignee: Infa S.A.
    Inventors: Paolo Magri′, Flavio Villani
  • Patent number: 8721617
    Abstract: A liquid component collecting device capable of more easily collecting a liquid component. A liquid component collecting device (100) is provided with: a flexible cylindrical liquid component storage container (21) having an opening at one end thereof; a cylindrical first housing container (22) for housing the liquid component storage container (21) and having an opening at one end thereof; and a first cap (23) connected to the opening in the liquid component storage container (21) and fitted to the opening in the first housing container (22). A pressure regulating space (26) independent of the internal space of the liquid component storage container (21) is formed between the outer side of the liquid component storage container (21) and the inner side of the first housing container (22).
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: May 13, 2014
    Assignee: JMS Co., Ltd.
    Inventors: Masayoshi Omori, Seishin Tanaka, Yasunori Okamoto
  • Patent number: 8721615
    Abstract: An ampoule including a casing, a facing side and a seal, wherein the casing has an outer diameter and the seal extends radially beyond the outer diameter and seals the facing side.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: May 13, 2014
    Assignee: TecPharma Licensing AG
    Inventors: Ulrich Moser, Markus Tschirren, Annette Drunk, Jürg Hirschel, Celine Kaenel, Kevin Mori, Scott Harris, John Puddy, Victor Chang
  • Publication number: 20140114275
    Abstract: Methods, apparatuses, kits and systems are disclosed that allow a transfer of medication from a manufacturer's vial, ampoule or other container through a closed system transfer to an intravenous apparatus and into a patient, while reducing additional steps, procedures, components required for the same transfer procedure to reduce sources of human error and medical administered errors.
    Type: Application
    Filed: October 21, 2013
    Publication date: April 24, 2014
    Inventor: Michael A. Creaturo
  • Publication number: 20140114276
    Abstract: A system for mixing or reconstituting agents including engageable syringe barrels, one of which having a male engagement region and the other a female engagement region. Each of the male and female engagement regions is provided with a screen. The screens are closely spaced from one another when the first and second syringe barrels are engaged with one another. The screens may take the form of a mesh, a plurality of protuberances, or cantilevered wedges having tapering thicknesses.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicants: BAXTER HEALTHCARE SA, BAXTER INTERNATIONAL INC.
    Inventors: Mark Schweiss, ATIF M. YARDIMCI, SCOTT R. ARIAGNO
  • Patent number: 8690854
    Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: April 8, 2014
    Assignee: Hospira, Inc.
    Inventors: Yei F. Moy, Stanley F. Pytel, John S. Ziegler, Jesse C. Darley, Douglas S. Rodenkirch
  • Patent number: 8684994
    Abstract: A fluid transfer assembly including a vented female vial adapter and male vial adapter for use with a pair of vials including a vial with contents under negative pressure for liquid drug reconstitution and administration purposes. The vented female vial adapter includes a venting arrangement and the male vial adapter includes a sealing arrangement for selectively sealing the venting arrangement. The fluid transfer assembly is designed such that only filtered air is drawn into the vial under negative pressure subsequent to reconstitution of liquid drug contents to ensure sterile conditions.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: April 1, 2014
    Assignee: MEDIMOP Medical Projects Ltd.
    Inventors: Nimrod Lev, Niv Ben Shalom, Amir Lev
  • Patent number: 8684993
    Abstract: Device for connecting a tubular part having a first end provided with a tip, and a second end provided with a connecting device. The connecting device connects an inside of the tubular part with a syringe and with the inside of a bottle, which bottle includes a neck having a stopper penetrable by the tip of the tubular part. Device includes a supporting device for sealing and fitting the device into place on the neck of the bottle in a tight and substantially centered manner. A holding device holds the tubular part in a displaceable manner relative to the supporting device in a penetration direction of the tip of the tubular part. Holding device includes a tight, deformable membrane with two edges, one edge of which is connected tightly to the tubular part and another edge of which is connected tightly to the supporting device.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: April 1, 2014
    Inventor: Hans Haindl