Materials Mixed Within Container Patents (Class 604/416)
  • Patent number: 11826550
    Abstract: A syringe-based device includes a housing and an actuator mechanism including a first member and a second member. The first member includes a syringe body and a plunger, the plunger being movably disposed within the syringe body. The second member includes a second member plunger seal and a valve operably and selectively coupled to the second member plunger seal such that the valve is positioned proximal of the second member plunger seal. The device also includes a first fluid reservoir and a second fluid reservoir. The device transitions from a first configuration to a second configuration in which the first type of fluid is expelled from the first fluid reservoir, to a third configuration in which the second type of fluid is expelled from the second fluid reservoir through the valve.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: November 28, 2023
    Assignee: True Concepts Medical Technologies, LLC
    Inventor: Michael Hopkins
  • Patent number: 11793721
    Abstract: In some embodiments, a reconstitution or medicinal fluid delivery device includes a transfer engine including two fluidly connected spikes, each configured to pierce a container. A check valve may be disposed between the two spikes to allow unidirectional flow from one container to the other. Physical access to a fluid outlet may be obstructed by a housing until the reconstitution or medicinal fluid delivery device is actuated, whereupon physical access to the fluid outlet is permitted. The reconstitution or medicinal fluid delivery device may be placed on a flat surface and actuated with force applied in a single direction toward the flat surface.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: October 24, 2023
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Joseph M. Giamo, Thomas Boyajian, Amey Mathakari, Anh Nguyen, Dhairya Kiritkumar Mehta
  • Patent number: 11759572
    Abstract: A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments and a fitment. The first compartment contains at least a first constituent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: September 19, 2023
    Assignee: Aktivax, Inc.
    Inventor: Amir Genosar
  • Patent number: 11753289
    Abstract: The present disclosure provides systems and methods for refilling fluid containers. A fluid container may include a bottle and a valve assembly. The valve assembly may include two valves and be configured to engage with the bottle and a filling head or dispensing head. A system is configured to provide pressurized fluid to the refillable container, monitor filling, determine when to stop filling, and determine how much fluid was provided. The valve assembly may include a float mechanism coupled to one of the valves of the valve assembly to ensure fluid flow is stopped when the fluid container is full. The fluid, which can include carbon dioxide, is stored in a storage tank. A flow system provides the fluid to a filling head, which engages with the fluid container. The flow system includes a transfer pump, valves, and sensors configured to provide the fluid to the filling head.
    Type: Grant
    Filed: February 17, 2023
    Date of Patent: September 12, 2023
    Inventors: Francis X. Tansey, Jr., Gwenivere R. Tansey
  • Patent number: 11752069
    Abstract: A cellular medicine transfer system includes: an adapter for a cellular medicine container including a first flow channel and a second flow channel through each of which a liquid and cells can flow; a cellular medicine container to which the adapter is attached, and in which a cellular medicine to be transferred is stored; an administration medium storage container that communicates with the first flow channel, and in which an administration medium is stored; a collection container for collecting a cellular medicine, that communicates with the second flow channel of the adapter; and a powering device that imparts motive power for transferring the administration medium from the administration medium storage container through the first flow channel to the cellular medicine container, and for transferring the cellular medicine and the administration medium from the cellular medicine container through the second flow channel to the collection container.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: September 12, 2023
    Inventors: Masakazu Inamori, Dai Otagiri
  • Patent number: 11744710
    Abstract: The present disclosure includes devices, apparatuses, kits, and methods for replacing a nucleus pulposus of an intervertebral disc with an implantable nuclear prosthesis filled with a curable silicone material in situ. Configurations of the present spinal implant devices include a flexible body defining an outer fillable enclosure that defines an outer chamber, an inner fillable enclosure that defines an inner chamber, and a proximal plug configured to be coupled to the inner fillable enclosure.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: September 5, 2023
    Inventors: W. Loren Francis, Mark A. Novotny, Cory R. A. Hallam, Jake Ganem
  • Patent number: 11684548
    Abstract: A device is provided for pooling a fluid from a container unit having at least one container, and includes an inlet port having at least one inlet channel configured for receiving the fluid or ambient air, and an outlet port having at least one outlet channel configured for delivering the fluid to an attachment. Both inlet and outlet ports are disposed on the device. A cavity is provided for accommodating insertion of the container unit for pooling the fluid from the at least one container. At least one spike is disposed in the cavity and configured for puncturing a stopper of the at least one container when the container unit transitions from an upper position to a lower position.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: June 27, 2023
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Mark David Schweiss, Daniel Edward Roush, Stefan Holzner, Seth Dale Jones, Tejas Dhyani, Michelle Shah, Madeleine Clare Gibson, Jessica Chung, Anthony Martin Looper
  • Patent number: 11673140
    Abstract: A device for separating and concentrating target particles or molecules from a fibrinogen containing sample of liquid comprises a container (1) for collecting the sample and a closure (2). The container (1) comprises a first end and a second end and at least one interior wall defining a reservoir portion (5) for receiving the sample. The reservoir portion (5) comprises at least one anchor element (4) to locally catch a polymerized fibrin pellet formed upon the addition of the sample into the container. The separation and concentration process is operated by trapping the target particles or molecules into the so-formed polymerized fibrin pellet that are captured on the anchor element (4).
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: June 13, 2023
    Inventors: Amar Rida, Sélène Ferrari
  • Patent number: 11655091
    Abstract: The present disclosure provides a flexible container (10). In an embodiment, the flexible container includes: a front panel (22), a rear panel (24), a first gusseted side panel (18), and a second gusseted side panel (20). The gusseted side panels adjoin the front panel and the rear panel along peripheral seals (41) to form (i) a top portion, (ii) a body portion, and (iii) a bottom portion. The top portion comprises a neck (27) and a fitment (30) in the neck. The top portion comprises a top handle (12) extending above the fitment, the top handle having a reciprocal attachment member (5). The bottom portion comprises a bottom handle (14) and a tether (6) extending from the bottom handle. A distal end of the tether has an attachment member (7), the attachment member adapted to secure to the reciprocal attachment member.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: May 23, 2023
    Assignee: Dow Global Technologies LLC
    Inventors: Liangkai Ma, Marc S. Black, Chad V. Schuette, Brian W. Walther, Fabrice Digonnet
  • Patent number: 11643266
    Abstract: The invention relates to a concentrated product storage cartridge for a diluting and dispensing container, comprising an external body, with an open lower end having a closing edge on the lower end thereof; and on the opposite end, there are flaps extending above the cylindrical tube of the external body, comprising a quick-coupling means; an opening for accessing the inner region thereof, where is placed an internal plunger, forming a filling region; and, on the upper end thereof, having quick-coupling means to be attached to the cover of cartridge. Said cover comprises upper ring flaps, arranged in order to interlock with the quick-coupling means of the internal plunger, forming a single assembly with an opening that can engage with the flaps of the external body, which are mounted in a way to provide displacement mobility in both directions downwards and upwards in relation to the internal plunger head.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: May 9, 2023
    Inventor: André Gustavo Sandri Silva
  • Patent number: 11622913
    Abstract: A compounder system having a vial puck configured for attachment to a vial containing a drug is provided. The vial puck includes features for facilitating uniform control of vials of various sizes in an automatic compounder system. The vial puck features may include a vial recess for receiving a vial of a particular size and securing the vial within the vial recess. The features may also include a cylindrical central portion, perpendicular extensions that extend from a top of the cylindrical central portion, a gear extending from the cylindrical central portion, and a sealing member disposed in the cylindrical central portion. The vial puck may include a cylindrical protrusion configured to press against a septum of the vial to form a seal between the vial puck and the vial. The sealing member may be configured to receive a needle of the compounder system therethrough to allow access to the vial.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: April 11, 2023
    Assignee: CAREFUSION 303, INC.
    Inventors: Christopher J. Zollinger, Neil Quitoviera, Dereck S. Ferdaws
  • Patent number: 11589843
    Abstract: An apparatus includes a transfer adapter, a puncture member, a disinfection member, and a fluid reservoir. The transfer adapter has a proximal end portion and a distal end portion, and defines an inner volume configured to receive the puncture member. The transfer adapter is coupled to the disinfection member. The distal end portion of the transfer adapter includes a port fluidically coupled to the puncture member and configured to be placed in fluid communication with a bodily-fluid of a patient. The proximal end portion is configured to receive a portion of the fluid reservoir to allow the fluid reservoir to be moved within the inner volume between a first position, in which a surface of the fluid reservoir is placed in contact with the disinfection member, and a second position, in which the puncture member punctures the surface to place the puncture member in fluid communication with the fluid reservoir.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: February 28, 2023
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Richard G. Patton, Shan E. Gaw
  • Patent number: 11534591
    Abstract: A system for facilitating instrument delivery through a peripheral intravenous catheter may include a catheter adapter having a proximal end, a distal end, and a lumen extending there through. The catheter adapter may include a side port. The system may include an extension tube extending from the side port. The system may include a blood control valve disposed in the lumen of the catheter adapter. The system may include a peripheral intravenous catheter extending distally from the catheter adapter.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: December 27, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Olivia Hu, Yiping Ma, Curtis H. Blanchard, Jonathan Karl Burkholz
  • Patent number: 11492191
    Abstract: The Improved Salad Dressing Preparation and Storage Container is a food preparation device that allows for conveniently measuring, mixing, and dispensing of homemade vinaigrette salad dressing. The device uses two adjacent, adjoined compartments that are volumetrically proportioned to allow for the recommended ratio of oil and vinegar (acid) to be consistently achieved by filling them with oil and vinegar to the same apparent level. The Improved Salad Dressing Preparation and Storage Container may also be configured for commercial sale pre-filled with the oil and vinegar contents, those kept separated by sealing the adjoined compartments using an adapted seal. The pre-filled container may be designed and marketed for secondary use by consumers for use in making their own vinaigrette salad dressing recipes.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: November 8, 2022
    Inventor: Bonnie Stepleton
  • Patent number: 11198547
    Abstract: A closure device for use with a container having a container neck comprises a cap member having a first fluid chamber and a housing having a second fluid chamber. The housing is arranged to move relative to the cap member between a first armed position and a second firing position. The housing includes a first plug member adapted to close a bottom aperture in the first fluid chamber in the first armed position. The cap member includes a second plug member adapted to close a bottom aperture in the second fluid chamber in the first armed position. In the second firing position the first plug member is removed from the aperture in the first fluid chamber and the second plug member is removed from the aperture in the second fluid chamber.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: December 14, 2021
    Assignee: Gizmo Packaging Limited
    Inventors: Jordan Maguire, Bernard Derek Frutin
  • Patent number: 11167903
    Abstract: In combination a spouted pouch to be filled with a flowable product by a filling machine, a plug, and a cap. The interference fit plug is releasably mounted over the top end of the neck of the spout body and hermetically seals the product passage of the spout body. The plug is adapted to be removed by the filling machine and to be replaced by pressing the plug onto the neck after filling of the pouch. The plug removal, filling, and replacing of the plug are preferably performed in an aseptic environment. The cap is after the filling of the pouch and the replacing of the plug onto the neck. The capping is preferably performed by a capping machine in a non-aseptic environment.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: November 9, 2021
    Assignee: SCHOLLE IPN IP BV
    Inventors: Christopher John Murray, Jeroen Pieter Fiere, Chad Mueller, David Bellmore
  • Patent number: 11090226
    Abstract: The present invention relates to a sealing device to seal a container, the sealing device including: a tip that defines an internal passage leading to an opening and is designed to allow connection to a collection member such as an enteral syringe, a non-return valve that is associated with the tip and is designed to open during collection of the contents of the container using the collection member, at least one air-return port, and an antibacterial filter associated with said at least one port.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: August 17, 2021
    Inventors: Jean-Marc Dubaele, Thierry Guillemaut
  • Patent number: 10898651
    Abstract: A mixing syringe including a valve mechanism is configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for mixing of the one or more substances, and a resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: January 26, 2021
    Assignee: UNL HOLDINGS LLC
    Inventors: Lance W. Wetzel, Gautam N. Shetty, Lou Castagna
  • Patent number: 10716548
    Abstract: The invention relates to syringes for storing and mixing components.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: July 21, 2020
    Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.
    Inventors: Yair Pilpel, Sivan Doron, Yuri Zherdev, Lior Erez, Ashley DeAnglis
  • Patent number: 10585021
    Abstract: Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: March 10, 2020
    Assignee: Instrumentation Laboratory Company
    Inventors: Gert Blankenstein, Hansong Zeng
  • Patent number: 10537692
    Abstract: A unit dose container for the containment of an intranasal formulation for use with the POD device.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: January 21, 2020
    Assignee: Impel Neuropharma, Inc.
    Inventors: John D. Hoekman, Alan Brunelle, Craig Kohring, Christopher Fuller
  • Patent number: 10442583
    Abstract: A process for the production of a device for dispensing eye drops. The process includes the steps of providing a first container and a second container configured to be engaged in a fluid-tight manner, providing a spacer, introducing a water-based solution inside the first container, introducing a solution or dispersion comprising a drug inside the second container, arranging the spacer between the first and second containers, engaging in a fluid-tight manner the second container and the first container, and freeze-drying the solution or dispersion comprising the drug.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: October 15, 2019
    Inventor: Marco Maria Gentile
  • Patent number: 10433825
    Abstract: Provided herein are systems for preparing and delivering fibrin sealant to a surface and methods of use thereof. In one embodiment, the system comprises: a. a quantity of a liquid mixture disposed within a container, the mixture comprising: I. fibrin or II. fibrinogen and Factor II; and b. a resin bed disposed within a vessel, the vessel capable of being in fluid communication with the container, wherein when in fluid communication, passage of the mixture through the vessel results in modification of the concentration of small molecules inhibitor(s) and/or inducer(s) within the mixture, favoring fibrin clot formation.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: October 8, 2019
    Assignees: Ethicon, Inc., Omrix Biopharmaceuticals Ltd.
    Inventors: Ashley DeAnglis, Yair Pilpel, Yuri Zherdev, Sivan Doron, Lior Erez
  • Patent number: 10350364
    Abstract: A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a valve between a first and second chamber that are slidably movable relative to each other and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: July 16, 2019
    Assignee: Windgap Medical, Inc.
    Inventors: Adam R. Standley, Christopher J. Stepanian, Brent R. Buchine, Michel Bruehwiler, Cole Constantineau, Jeffrey Thomas Chagnon, Robert Brik
  • Patent number: 10155183
    Abstract: Embodiments of the present invention relate to a filtration device and method for filtering liquids. In conventional devices, a liquid is placed in a vial, and a plunger, having a filter membrane located at one end, is depressed into the vial, causing the liquid to pass through the filter membrane into the interior of the plunger, where it is stored until required for further processing. However, such plungers are typically made of a plastics material. It is undesirable to store the filtered liquid in contact with plastics for extended periods of time, as contaminants may leach from the plastics material into the sample. In embodiments of the present invention, a filtrate receptacle made from a different material to the plunger, such as a glass material, is located in the interior of the plunger and the filtered liquid collected in the filtrate receptacle after passing through the filter membrane.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: December 18, 2018
    Inventors: Stevan Paul Tortorella, Navin Deepal Pathirana, Geraint Seymour
  • Patent number: 10099012
    Abstract: Disclosed are a closure system for an applicator attachment on a container for pharmaceutical preparations and to a use of the closure system, a syringe for medical purposes, including a container for pharmaceutical preparations and a closure system, and a method of assembling a syringe. The aforementioned operate such that splash prevention and a venting function are integrated in the closure system.
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: October 16, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Friedrich Haefele, Markus Hemminger, Tobias Sachsse, Klaus Boje
  • Patent number: 9642774
    Abstract: Liquid container with a predetermined break point (4), which is covered by an elastomer septum (3). The container forms a hollow body (10) made of a single material that is compatible with critical liquids such as medicines. The elastomer septum (3) and the predetermined break point (4) can be pierced by a hollow needle (51) in order to withdraw liquid from the container.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: May 9, 2017
    Assignee: Stryker European Holdings I, LLC
    Inventor: Christoph Helmut Sattig
  • Patent number: 9216175
    Abstract: The invention provides sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof. The invention further provides sublingual formulations containing buprenorphine and naloxone, pharmaceutically acceptable salts thereof or derivatives thereof. The invention further provides a method of treating pain or opioid dependence by administering sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof to a patient in need thereof.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: December 22, 2015
    Assignee: Insys Pharma, Inc.
    Inventors: Kiran P. Amancha, Chandeshwari S. Chilampalli, Venkat R. Goskonda
  • Patent number: 9039672
    Abstract: A coupling component is disclosed for transmitting medical substances, comprising two channels for conveyance of medical substances in two substantially opposite directions and a means for releasable connection to a second coupling component having a further channel for creating a coupling. The connecting means is a thread. A method for conveying medical substances to and from a container is also disclosed.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: May 26, 2015
    Assignee: Carmel Pharma AB
    Inventor: Claes Wallen
  • Patent number: 9039673
    Abstract: A withdrawal spike unit (200) comprises a withdrawal spike component (30?) and an integrally formed adapter component (60?) that is adapted to couple with a vial (10) in a safe and secure manner. The integral formation of the component parts (30?, 60?) makes fully automated manufacture and assembly of assemblies comprising such a withdrawal spike unit (200) coupled to a vial (10) possible. As such, human errors associated with the assembly at the point of use are mitigated.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: May 26, 2015
    Assignee: Novartis AG
    Inventors: Dietmar Weitzel, Astrid Hoffmann
  • Publication number: 20150141913
    Abstract: An apparatus comprises a plunger able to fit in a cartridge or syringe. The plunger includes an outer portion and a deflection portion. The outer portion is able to engage the body of the cartridge or syringe. The outer portion is operable to apply a first radial force to the cartridge or syringe. The deflection portion is positioned within the outer portion and is movable between a locked position and an unlocked position. The deflection portion in the unlocked position causes the outer portion to apply a second radial force to the cartridge or syringe.
    Type: Application
    Filed: June 26, 2013
    Publication date: May 21, 2015
    Inventors: Rush L. Bartlett, II, Peter M. Greco, JR., Barry J. Davignon
  • Patent number: 9022653
    Abstract: The present invention refers to a flexible multiple chamber bag comprising: a) three adjacent chambers, a first chamber partially separating a second upper chamber from a third lower chamber by first and second welded seams, b) said second chamber and said third chamber being partially connected by a third welded seam, c) said first welded seam being non-peelable and said second and third welded seams being peelable said second and third welded seams having the shape of an inverse letter “V” each second and third welded seam starting at the basic point of said “V” and terminating essentially in a right angle at the circumference weld of said bag, said bag comprising a hanger flap extending from the top end of said bag and a medical port welded to the lower end of said circumferential weld.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: May 5, 2015
    Assignee: B. Braun Melsungen AG
    Inventors: Michel Pittet, Caroline Ansermet, Bastien Ecabert, Cedric Berchier
  • Patent number: 9011408
    Abstract: Delivering a blood processing solution to blood in a blood bag includes coupling a first tube to a vented spike at one end and to a Y-shaped tube connector at a second end. An in-line microbiotic barrier filter is coupled to the first tube between its ends. A second tube is coupled to a transfer bag at one end and to the Y-shaped tube connector at its other end. A third tube is coupled to the output of the Y-shaped tube connector and sealed at its distal end. The blood bag includes a fourth tube that is sealed at a distal end. The third tube is welded to the fourth tube using a sterile tubing welder, wherein a functionally-closed, sterile flow path through which the blood processing solution can flow into the blood bag is maintained.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: April 21, 2015
    Assignee: Biomet Biologics, LLC
    Inventor: Alan Gray
  • Patent number: 9005181
    Abstract: A connector for providing sterile access to a flexible container is provided that comprises a tubular member having a first portion and a second portion, each of the first portion and the second portion having an open end. The first portion and second portion are joined to each other by a frangible segment, with each of the first portion and the second portion having a gripable surface associated therewith that is configured to facilitate the application of torsional force to the tubular member at the frangible segment. Upon the application of a sufficient amount of torsional force, the frangible segment will break, permitting the first and second portions to be separated from each other.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: April 14, 2015
    Assignee: Fenwal, Inc.
    Inventors: Daniel Lynn, Richard L. West, Bryan Blickhan, Phoung Tran, Shawn Davis
  • Patent number: 8992490
    Abstract: The invention relates to a drip chamber for an infusion device and an infusion device having such a drip chamber, by means of which medical solutions can be fed to a patient, such as infusion solutions for chemotherapy. The drip chamber (1) according to the invention is provided for connecting to a fastener (8) of an infusion container (2), comprising a withdrawal part (25) for withdrawing fluid, having an opening (28) closed by a penetrable membrane (27) and an injection part (26) for injecting a fluid, having an opening (30) closed by a penetrable membrane (29). The connecting part (7) and/or piercing spike (11) of the drip chamber (1) according to the invention is designed such that a snap-fit or latching connection to the injection part (13) and/or the withdrawing part (25) of the fastener (8) of the infusion container (2) can be produced when the connecting part (7) of the drip chamber (1) is connected to the fastener (8) of the infusion container (2).
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: March 31, 2015
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Torsten Brandenburger, Ismael Rahimy
  • Patent number: 8973622
    Abstract: Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to a at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: March 10, 2015
    Assignee: ICU Medical, Inc.
    Inventors: George A. Lopez, Thomas F. Fangrow, Peter Leissling, Matthias Janssen
  • Patent number: 8939326
    Abstract: The present invention proposes a dispensing container (1) A for probiotics (2) in a viscous or liquid carrier (3), the probiotics (2) having a higher specific weight than the viscous or liquid carrier (3), wherein the container (1) comprises a reservoir (4) for holding the carrier (3) and a dispensing head (5) being in fluid connection with the reservoir (4), the dispensing head (5) comprising at least one outlet (6), wherein the concentration of the probiotics (2) decreases from the outlet (6) of the dispensing head (5) towards a bottom portion (1a) of the reservoir (1).
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: January 27, 2015
    Assignee: Nestec S.A.
    Inventor: Karl-Josef Huber-Haag
  • Patent number: 8926583
    Abstract: The present invention concerns a male connection part for connection with a female piercing member protection device having a longitudinal cylinder-like body having a longitudinal axis C, a first side and a second side, an outer and an inner surface, a barrier member arranged at the center of the first side of the male connection member, intersecting the longitudinal axis C, and a fluid communication channel extending from the barrier member of the male connection part to the second side of the male connection part, wherein the male connection part further comprises at least one turning grip protrusion to provide for an increased turning friction between the female piercing member protection device after assembly.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: January 6, 2015
    Assignee: Carmel Pharma AB
    Inventors: Anna Ellstrom, Tobias Rosenquist
  • Publication number: 20140378937
    Abstract: A dispensing assembly includes a syringe body having a barrel and a dispensing tip. The dispensing assembly further includes a mixing and plunging assembly configured for coupling with the syringe body and comprising a mixer and a plunger. The mixer is configured for mixing material in the barrel and has a rod and a mixing element removably connected with the rod. The plunger is configured to dispense material from the barrel through the dispensing tip. Also, the rod is configured to be detached from the mixing element and used to push material out of the dispensing tip.
    Type: Application
    Filed: June 23, 2014
    Publication date: December 25, 2014
    Inventors: Benjamin B. Anderson, Kevin C. Geppert, Jon E. Hoogenakker, Huadong Lou, Zachary Rzeszutek, Mark Stevenson
  • Patent number: 8910832
    Abstract: Device for the preservation of substances to be kept separate until their application includes a container (2), which is provided with an at least partially deformable body (6), and a delivery mouth (4), on which there is provided a delivery element for delivering the mixture. A watertight chamber (5) is arranged between the delivery mouth and the body of the container and is provided with a connection mouth (12) for the connection to the body (6), which is closed by cap means (20). A component of the substance to be delivered is contained in the watertight chamber (5), whereas another component is contained in the body (6). The communication between the two components is established by removing said cap, by interference between the walls of the cap and the walls of the body.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: December 16, 2014
    Assignee: Inge S.p.A.
    Inventor: Alessio Nobbio
  • Patent number: 8911420
    Abstract: A device (1) for the containment of platelet concentrates includes at least a bag (2) defining at least a containment chamber (3) having at least a mouth (4) for the entry of a platelet concentrate and at least a connection element for connection to an infusion line associated with the bag in correspondence to the mouth; the connection element includes a first and a second portion (5a, 5b) integrally associated together and includes at least a constantly open duct (6), passing through the first and the second portion and communicating with the chamber, where the first portion is associable with the infusion line and the second portion is associated with the bag in correspondence to the mouth, the first portion being separable from the second portion in such a way to interrupt the duct and define an opening (8) accessible from outside and including closing element (9) of the opening.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: December 16, 2014
    Assignee: Biomed Device S.R.L.
    Inventor: Marco Bertoni
  • Patent number: 8911421
    Abstract: A system for mixing the contents of a first container and a second container. The system includes the first container that has container body with an opening fluidly connected to a cavity defined by the container body, a first substance contained in the cavity, and a stopper sealing the opening. The second container includes a port assembly including a port housing connected to the second container and a retainer constructed to connect to the first container. The retainer is configured to rotate and move axially relative to the port housing, wherein relative rotation between the port housing and the retainer causes the retainer to move axially relative to the port housing. The port assembly further includes an axially fixed actuator constructed to force the stopper into the first container when the retainer is rotated relative to the port housing.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: December 16, 2014
    Assignee: Hospira, Inc.
    Inventors: John A. Domkowski, David L. Foshee, Theodore J. Mosler, Edward Browka
  • Patent number: 8905994
    Abstract: Valve assemblies for use with a liquid container and a drug vial for enabling an initial transfer of liquid contents from the liquid container to the drug vial for liquid drug formation purposes and subsequent transfer of liquid drug contents from the drug vial to the liquid container for administration purposes. Liquid drug transfer sets can include a valve assembly pre-attached to a liquid container. Alternatively, liquid drug transfer sets can include a valve assembly packaged in sterile blister packaging ready for attachment to a liquid container prior to use.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: December 9, 2014
    Assignee: MEDIMOP Medical Projects, Ltd.
    Inventors: Nimrod Lev, Niv Ben Shalom
  • Patent number: 8894627
    Abstract: A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: November 25, 2014
    Assignee: J & J Solutions, Inc.
    Inventors: Jared Garfield, John Slump, Gregory Lyon
  • Patent number: 8882736
    Abstract: A container for re-suspending sedimented medicament comprises a reservoir for containing a suspension of particles in a liquid, a dispensing portion, and a sealing portion. The sealing portion is arranged to be in fluid communication with the reservoir via an orifice. The orifice is positioned between the dispensing portion and the sealing portion, and allows a turbulent flow of the liquid from the reservoir into the sealing portion to enable re-suspension of particles that have sedimented out of the liquid in the sealing portion.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: November 11, 2014
    Assignee: Norton Healthcare Limited
    Inventor: Martin Oliver
  • Patent number: 8883762
    Abstract: The present invention provides a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. Glucose-like degradation and hydrolysis is avoided during sterilization and storage, while maintenance of a neutral mixture pH is achieved by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further discloses a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: November 11, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Thomas Zimmeck
  • Patent number: 8882739
    Abstract: A port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a port housing for connection to a second container, and a retainer for connection to a first container, wherein the retainer rotates relative to the port housing and is constructed to move axially within the port housing. An actuator is axially fixed within the port housing and forces a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing. The assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: November 11, 2014
    Assignee: Hospira, Inc.
    Inventors: John A. Domkowski, John Sundquist, Benjamin Leo Rush, David L. Foshee, Theodore J. Mosler, Edward Browka
  • Patent number: 8882737
    Abstract: A self standing bag having two side wall sheets and a bottom sheet. To flatten the bag, the bottom sheet is sandwiched between the two side wall sheets and symmetrically folded along a line parallel to its bottom edge, separating the bag into a four-layer part and a two-layer part. In the two-layer part, the bag includes first sloped sealing lines extending between a first two points on the top edges of the side wall sheets and spaced from the vertical side wall edges by a first distance, to a second two points spaced from the vertical edges of the side wall sheets by a second distance less than the first distance. The four-layer part includes second sloped sealing lines extending between the second two points and a third two points on the bottom edges of the side wall sheets.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: November 11, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Thomas Graf, Paul Gastauer, Philippe Laffay, Francois Dumont D'Ayot, Pascal Lengrand, Bertrand Thibault
  • Patent number: 8876790
    Abstract: A connector according to the invention includes a first connection region for connecting a first container, a piercing element and a break-open element, wherein the piercing element has a first end section and a second end section and a channel, running from the first end section to the second end section, for transporting a medicinal active substance, wherein the first end section is formed for piercing a membrane of the first container connected in the first connection region, and, at the second end section, the break-open element is attached such that it can be broken open and/or broken off, wherein, in the attached state, the break-open element seals the channel of the piercing element in liquid tight fashion.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: November 4, 2014
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Ismael Rahimy, Torsten Brandenburger
  • Patent number: 8864737
    Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: October 21, 2014
    Assignee: Nipro Corporation
    Inventors: Mitsuru Hasegawa, Atsushi Ishikawa, Suguru Oyagi, Takeshi Ohguro