Materials Mixed Within Container Patents (Class 604/416)
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Patent number: 7875016Abstract: A flexible multi-chamber container for preparation of medical mixed solutions includes at least three chambers separated from each other by leaktight seams. The chambers are designated to be filled with different solutions and are separated from each other by leaktight seams. At least a part of the first leaktight seam is provided with a separation zone to be opened for fluid transfer from the first chamber into the second chamber. At least a part of the second leaktight seam is provided with a separation zone to be opened for fluid transfer from the second chamber into the third chamber. The leaktight seams are arranged and the separation zones are formed such that, in use of the container for preparation of the medical mixed solution, the first separation and second separation zones are opened in a sequential order. The first zone is opened before the second separation zone is opened. Thus, the components are mixed one after another in a predetermined sequential order.Type: GrantFiled: June 16, 2005Date of Patent: January 25, 2011Assignee: Fresenius Kabi Deutschland GmbHInventors: Olof Pahlberg, Johan Engholm, Manus O'Donnell, Torsten Brandenburger, Gerald Wegner
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Patent number: 7875015Abstract: A pharmaceutical container with an improved peelable seal is provided, wherein the container may be made of a flexible polymeric film and comprises at least one peelable seal comprising at least two substantially straight sections which are connected by a rupture zone (5), The rupture zone of the peelable seal may be curved over its whole length between the straight sections. The container may be used for storing pharmaceutical substances, solutions for dialysis, solutions for infusion and/or agents for nutrition.Type: GrantFiled: June 16, 2005Date of Patent: January 25, 2011Assignee: Fresenius Kabi Deutschland GmbHInventors: Olof Pahlberg, Johan Engholm, Manus O'Donnell
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Publication number: 20110004170Abstract: An apparatus for preparing a pharmaceutical for transient application includes a tray having a sealed compartment, a vial of an ophthalmic formulation of mitomycin-C, a diluent carrier containing sterilized water, and a syringe that are all contained together in a single package. The component parts of the apparatus are used together to reconstitute the contents of the vial with the water in the diluent carrier, and then draw the reconstituted drug into the sealed compartment of the tray by a suction force produced by the syringe. In the tray compartment, the reconstituted drug is absorbed in an absorbent pad. The tray is opened to remove the pad and the absorbed drug from the tray compartment for use of the pad in transient application of the drug.Type: ApplicationFiled: September 15, 2010Publication date: January 6, 2011Applicant: MOBIUS THERAPEUTICS, LLCInventor: Edward J. Timm
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Publication number: 20100331773Abstract: A drug storage and delivery device (1) comprising a reservoir (102) containing a liquid, a vial (101) containing a dry drug, such as a lyophilized drug, means (110) for forcing the liquid from the reservoir to the vial, via an established fluid connection, and valve means (106-108) to ensure a tight fluid connection between reservoir and vial can be established before the fluid paths are opened.Type: ApplicationFiled: November 21, 2008Publication date: December 30, 2010Applicant: NOVO NORDISK HEALTHCARE A/GInventors: Morten Revsgaard Frederiksen, Per Valentin Nielsen
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Publication number: 20100318063Abstract: A syringe system for dispensing or injecting one or more fluids is provided. The syringe system includes a hollow body that retains cartridge(s) and/or syringe(s) each containing a fluid, such as an injectable fluid e.g., a catalyst in one cartridge and a polymer in the other. Upon use for dispensing two fluids, the syringe system mixes the two fluids immediately prior to or concurrently with the dispensing or injecting of the fluids. The syringe system can also be configured to independently dispense a single fluid or immediately dispense multiple fluids sequentially.Type: ApplicationFiled: June 10, 2010Publication date: December 16, 2010Applicant: CLEO COSMETIC AND PHARMACEUTICALS CO., LLCInventor: David B. SOLL
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Patent number: 7837666Abstract: The invention provides container systems, kits and methods for peritoneal dialysis (PD) solutions. Such a system, for example, includes a first compartment that contains a PD osmotic agent and a second compartment that contains a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. The invention provides, in other aspects, such systems, kits and methods that provide protective structure which inhibits breaking of a seal prior between the second compartment and an outlet of the system, prior to breaking of a seal between the first and second compartments.Type: GrantFiled: January 26, 2006Date of Patent: November 23, 2010Assignee: Fresenius Medical Care North AmericaInventors: Lynn E. Jensen, Olli Tuominen, Jay M. Lan
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Publication number: 20100292667Abstract: A dermatologic peel comprising alpha hydroxyl acid and metal hydroxide nanocomplexes as neutralizing agents to continually reduce the activity of the system when the acid and neutralizer components are mixed. For example, a 30% glycolic acid gel mixed with a fluidized magaldrate neutralizer can be applied to the skin and will self-neutralize to a skin-compatible pH within a few minutes, effectively exfoliating the skin without a separate neutralization step. The peel is advantageously applied from a two-component system that mixes the components.Type: ApplicationFiled: May 25, 2010Publication date: November 18, 2010Inventors: R. MacDonald Smith, Otto William Wendel, Archie McBride
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Publication number: 20100286603Abstract: A kit and method for preparing a Degarelix solution for administration to a patient. The kit includes a first chamber containing lyophilised Degarelix, a second chamber containing water, a syringe for transferring the water from the first chamber to the second chamber, at least one of a hypodermic needle, a safety needle device, or a needleless device for delivery of the Degarelix to the patient, and a mixing apparatus. The mixing apparatus is configured to receive the first chamber to mix the Degarelix and water to produce a Degarelix solution suitable for deliver to a patient. The method includes transferring a volume of water from a first chamber into a second chamber containing lyophilised Degarelix, connecting the second chamber to a mixing apparatus and mixing the water and lyophilised Degarelix for a period of time.Type: ApplicationFiled: May 5, 2010Publication date: November 11, 2010Inventor: Carin WINDERSTRÖM
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Patent number: 7828788Abstract: A connector for connecting a container with a fluid preparation device for preparing a fluid, in particular a container with a concentrate for the preparation of dialysis fluid, as well as the combination of the connector, the corresponding container and the fluid preparation device. In order to simplify the handling during both the manufacturing process of such containers and the connection of such containers to the fluid preparation devices, the connector connects a first and second fluid line of the container with a third and fourth fluid line of the fluid preparation device with two laterally spaced-apart mounting elements which each incorporate one of two orifices terminating the first and second fluid lines.Type: GrantFiled: May 16, 2007Date of Patent: November 9, 2010Assignee: Fresenius Medical Care Deutschland GmbHInventors: Winfried Brehm, Thierry Dupin, Ilona Eggert, Thomas Faulhaber, Thomas Graf, Philippe Laffay
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Publication number: 20100268193Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.Type: ApplicationFiled: June 4, 2010Publication date: October 21, 2010Inventors: James M. Verespej, Philip Dowds
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Publication number: 20100256591Abstract: A mixing device having a body, a pusher, an abutter and a mixer is provided. The body is tubular and has a fore end, a rear end and multiple chambers. Each chamber has a fore opening, a rear opening and a cap sealing the fore opening. The cap protrudes forwardly and has an outer surface and a top. The pusher has multiple rods respectively inserted in the chambers from the rear openings. The abutter has multiple tubes for respectively breaking the caps through to communicate with the chambers and each having a blunt end. The mixer is tubular and has an outlet, a connector and a mixing shaft mounted therein. The connector is connected to the fore end of the body and communicates with the tubes of the abutter. The cap may be easily injection-molded and agents may be filled directly into the chambers to ensure reliable operation.Type: ApplicationFiled: March 15, 2010Publication date: October 7, 2010Inventors: Phillip Phung-I HO, Chung-Chieh LEE
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Publication number: 20100249699Abstract: A container supplies a medicinal formulation that includes a hydrophilic polymer and an active agent capable of bonding to the polymer. The container includes a first compartment for storing the polymer and a second compartment fluidly isolated from the first compartment for storing the active agent. A frangible barrier is shared between the compartments. A fluidic outlet is disposed on the container to dispense the medicinal formulation. Dispensing of the medicinal formulation includes rupturing the frangible barrier, mixing the polymer and active agent together to form the medicinal formulation, and administering the medicinal formulation provided from the fluidic outlet to a patient. The polymer can be PEG, while the active agent can be magnesium.Type: ApplicationFiled: March 26, 2009Publication date: September 30, 2010Applicant: Warsaw Orthopedic, Inc.Inventors: Josee ROY, Toya D. Kimble, Jeffery C. Marx
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Patent number: 7803148Abstract: Drug solutions (or other combinations of vehicle with entrained drug) are prepared by removing drug from one or more masses of a solid form of the drug. The solid form of the drug may be sparingly soluble or insoluble in water. Examples of devices for holding solid drug and facilitating delivery of such drug to targeted regions are also described.Type: GrantFiled: June 7, 2007Date of Patent: September 28, 2010Assignee: NeuroSystec CorporationInventors: Thomas J. Lobl, Anna Imola Nagy, Jacob E. Pananen, John V. Schloss
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Patent number: 7789854Abstract: A medical treatment kit and methods of use thereof is provided. The kit includes a container, two or more chambers within the container, an antiseptic agent disposed in one of the chambers, a cleansing agent disposed in a separate chamber and an applicator. The agents are not contacted until immediate use of the kit is required. The medical treatment kit is used to administer an antiseptic shampoo or other medical composition to a patient with an open wound or injury. The kit is designed to be simple to use in an emergency situation. The kit is also designed to deliver medical compositions that are at the peak of potency.Type: GrantFiled: May 12, 2005Date of Patent: September 7, 2010Inventor: Anthony R. Talamonti
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Patent number: 7780621Abstract: A blood chamber for an extracorporeal blood circuit comprises a blood inlet port (2), a blood containment chamber (3), a first conduit (8) which connects the blood inlet port (2) with the blood containment chamber (3) and which has an end tract (8a) that terminates in the blood containment chamber (3) with a horizontal inlet component. The first conduit (8) comprises a pre-terminal tract (8b) which precedes the end tract (8a) and which has at least a second horizontal component which is directed in an opposite direction to the horizontal inlet component. The blood chamber is used in an arterial line of a dialysis set for guaranteeing a regular and gentle blood flow.Type: GrantFiled: July 6, 2005Date of Patent: August 24, 2010Assignee: Gambro Lundia ABInventors: Robert Neri, Andrea Paltrinieri
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Patent number: 7780644Abstract: A medicine discharge stopper for a medical bag of a type where a multiple of medicines are mixed, aiming to positively exclude a possibility of generation of erroneous operation that administration is done without opening the mixing seal. The medical bag is formed from a soft film and has an inner space, which is divided into compartments 20 and 22. An outlet port 12 is provided so that it is opened to the first compartment 20. The stopper includes split halves, which, when tied, form an inner space 34 of the outlet port 12. The combination is done under a resilient force by cantilever fashioned extending parts 38. When the weak seal portion is opened, an impact-like hydraulic force is generated and the bag is widened, which causes the flaps 30 and 32 to be opened against the resilient force, resulting in a release of the stopper. The flaps 30 and 32 are made separable from the body parts, which allows the stopper to be also utilized for a holder of needle during the execution of infusion process.Type: GrantFiled: October 10, 2006Date of Patent: August 24, 2010Assignee: Ajinomoto Co., Inc.Inventors: Chiharu Miyajima, Yasuhiro Muramatsu
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Patent number: 7776414Abstract: The present invention has an object to provide an infusion container with multiple chambers, where the peel strength of the boundary portion between one and another of multiple medicament chambers is stabilized irrespective of the construction material and structure of the film. The present invention provides an infusion container 10 with multiple chambers, which is formed from a thermoplastic resin film and has a plurality of medicament chambers 11 and 12 for housing medicaments, wherein the medicaments chambers 11 and 12 are liquid-tightly sealed by a peelable weak seal part 15, the weak seal part 15 is formed to have a plurality of melt-bonding parts different in the melt-bonding strength, the strong melt-bonding part having a largest melt-bonding strength among these melt-bonding parts is dispersed and distributed in the weak seal part 15, and the total occupied area of the strong melt-bonding part is less than 25% of the area of the weak seal part 15.Type: GrantFiled: March 27, 2003Date of Patent: August 17, 2010Assignee: Hosokawa Yoko Co., Ltd.Inventors: Toshiharu Iwasaki, Masataka Kotani, Kiyokazu Ishiwatari, Katsuyuki Yoshikawa
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Patent number: 7758556Abstract: A collection device for collecting bone material during a spinal fusion surgical procedure so that the bone material can later be used as a graft material for the fusion procedure. The device includes a container that collects the bone and other material that is removed from the patient during the surgical procedure through a suction hose. The device includes a plunger having a filter plate sealed to the inside of the container. The plunger is pushed down into the collected material in the container so that blood and other liquids are forced through the plate to be separated from the bone material. A cover at the bottom of the container can be removed to remove the collected bone material.Type: GrantFiled: August 8, 2006Date of Patent: July 20, 2010Inventors: Miguelangelo J. Perez-Cruet, John R. Pepper, John A. Miller
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Patent number: 7753085Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.Type: GrantFiled: November 1, 2006Date of Patent: July 13, 2010Assignee: ForHealth Technologies, Inc.Inventors: Dennis Tribble, Joel A. Osborne, Abdul Wahid Khan, Edward J. Lefebre
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Publication number: 20100168712Abstract: A reconstitution device for storing a first component of a pharmaceutical preparation includes a receptacle, a cap having a first end secured to the receptacle, a second end, and an inner bore having a central aperture. The device further includes a stopper located between the receptacle and the cap, the stopper including a portion capable of being perforated. The device also includes a plunger secured to the second end of the cap, a locking mechanism located in the cap, and an actuating mechanism. The actuating mechanism may prevent the device from inadvertent activation.Type: ApplicationFiled: May 24, 2007Publication date: July 1, 2010Applicant: BAYER HEALTHCARE LLCInventors: Jonathan David Tuckwell, Robert Dyer, Robert Owen Kivlin, John Peter Palmer-Felgate, Matthew Burgess Avery, Kevin George Skinner, Chris Kadamus, Lee Wood, Peter Schwan, Ben Arlett
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Patent number: 7745106Abstract: Methods and devices for preparing a solid-fibrin web are provided. One method may include drawing blood from a patient, separating plasma from the blood, contacting the plasma with a calcium-coagulation activator and concurrently coagulating and axially centrifuging the plasma to form the solid-fibrin web. The solid-fibrin web may be suitable for regenerating body tissue in a living organism. Devices used in the methods may also be provided.Type: GrantFiled: June 26, 2003Date of Patent: June 29, 2010Assignee: Cascade Medical Enterprises, LLCInventors: Roberto C. Beretta, Nicholas A. Grippi
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Patent number: 7722594Abstract: The invention relates to a medical bag which is intended for the infusion of a medicament by means of gravity. The inventive bag comprises: at least two compartments, namely a first compartment (1) containing a medicament in the form of a solution and a second compartment (2) containing a rinsing solution; and means for separating/communicating the compartments, which prevent the rinsing solution from automatically entering the medicament compartment except at the end of the infusion period. The rinsing solution ends the infusion, by rinsing the medicament bag and the infusion line, such as to prevent any risk of contamination or leakage of residual medicament from the bag or line.Type: GrantFiled: June 2, 2005Date of Patent: May 25, 2010Assignee: Laboratoire AguettantInventor: Pierre Frezza
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Patent number: 7703486Abstract: An apparatus for the handling of hazardous fluids includes a collection vessel, a collection vessel connector, a dose control connector, a unit dose container, a delivery control connector, and a delivery site access device. The collection vessel contains the fluid prior to dispensing, the unit dose container contains a predetermined amount of the fluid for dispensing, the delivery site access device provides access to an intended delivery site, and the connector attaches pieces of the apparatus to one another. The method of the invention allows needle-free connections to be made for the apparatus, using a predetermined arrangement of the pieces of the apparatus, and in one embodiment, employs deformable elastomeric valves capable of creating a decreased pressure at a valve surface, so that upon closure of said valves, a fluid on the surface on the valves is withdrawn within the connector.Type: GrantFiled: June 6, 2006Date of Patent: April 27, 2010Assignee: Cardinal Health 414, Inc.Inventor: Jerry Costanzo
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Publication number: 20100087779Abstract: A mixing portion is provided between a medical fluid container connecting portion 5 to which an opening of a medical fluid container 100 for a sclerosing agent is to be connected and a gas container connecting portion 6 to which an opening of a gas container 200 for a gas is to be connected. The mixing portion has a communication passageway R for communication between the openings of the containers 100 and 200 connected to the connecting portions 5 and 6. The mixing portion is deformable such that relative positions of the connecting portions 5 and 6 can be changed.Type: ApplicationFiled: August 8, 2007Publication date: April 8, 2010Applicant: JMS CO., LTD.Inventors: Yasuhiro Shimizu, Shuro Hayashi
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Publication number: 20100069817Abstract: A container (10) comprising a plurality of compartments (A, B, C) separated by compartment dividers (6), and an inlet connector (3) for receiving a liquid via a connection tube (2). The compartment dividers rupture when a sufficient pressure is applied by a liquid or gas introduced into the container (10) through the inlet connector (3). Some of the compartments comprise powder, which dissolves at the introduction of liquid into the container. A system, process and use in the field of dialysis are also disclosed.Type: ApplicationFiled: June 15, 2007Publication date: March 18, 2010Inventors: Thore Falkvall, Per-Olov Carlsson
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Patent number: 7678097Abstract: A container is provided comprising a body defined, at least in part, by a film, the body including at least one side seal, at least two chambers separated, at least in part, by a peelable seal, and the film including a sealant layer having a bimodal thermal behavior such that the side seal is a permanent seal and the peelable seal can, at least in part, be separated.Type: GrantFiled: November 12, 1999Date of Patent: March 16, 2010Assignee: Baxter International Inc.Inventors: Francesco Peluso, Tranaeus Anders, Dirk Faict, Patrick R. Balteau, Paul-Andre Gollier, Jean-Luc Dewez, Eric J. Henaut, Vincent Houwaert, Philippe Lambert
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Publication number: 20100049161Abstract: An ampoule made of plasties material, for liquid or suspension pharmaceuticals, has a reservoir linked to a removable head by a channel in a neck portion. The channel has a trap, thus located between its reservoir and the head, in the form of an elongated restriction and/or a bend to trap liquid or suspension which may settle during storage, and prevent either reaching the head.Type: ApplicationFiled: November 22, 2007Publication date: February 25, 2010Inventors: Ian Gardner Cameron McAffer, Peter Ernest Tasko
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Patent number: 7662139Abstract: An apparatus for use in a fluid processing system having a pump. The apparatus includes a pump cassette for use with the pump. The pump cassette includes at least one pump chamber and a first port in selective fluid communication with the at least one pump chamber. A spiking assembly includes at least one hollow spike having a piercing end for piercing a first container. The at least one hollow spike includes a first spike in fluid communication with the first port of the pump cassette.Type: GrantFiled: October 30, 2003Date of Patent: February 16, 2010Assignee: Deka Products Limited PartnershipInventors: Jason A. Demers, David W. McGill, Brian Tracey, James D. Dale, Larry B. Gray
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Publication number: 20100036359Abstract: The present disclosure provides a medical device package including a container for receiving a medical device having an area configured for storing at least one agent and a port for permitting the passage of a contact material between the outside the container and the area configured for storing the agent.Type: ApplicationFiled: August 20, 2009Publication date: February 11, 2010Inventors: Joshua B. Stopek, Matthew D. Cohen, Joseph Hotter, William Denman
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Publication number: 20100030182Abstract: The invention refers to a new system for packaging pharmaceutical compositions comprising active principles that may be administered intravenously, in particular it concerns a system for packaging in bottles which makes it possible to ensure the complete transfer of the content of the bottle into the liquid for intravenous infusion and at the same time prevent any accidental contact with the active principle by the health-care personnel preparing said intravenous infusion, and a complete kit for intravenous administration.Type: ApplicationFiled: September 28, 2007Publication date: February 4, 2010Inventors: Paolo Magri', Flavio Villani
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Publication number: 20100016826Abstract: A bushing for the preparation of a suspension or solution formed by mixing a first product with a second product, to allow a first bottle initially containing the first product to communicate with a second bottle initially containing the second product is provided.Type: ApplicationFiled: November 23, 2006Publication date: January 21, 2010Applicant: SANOFI-AVENTISInventors: Yves Billiet-Prades, Felipe Sanchez-Cifuentes, Ricardo Perez Lopez
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Publication number: 20100004620Abstract: The present disclosure provides a medical device package including a container for receiving a medical device and a self-puncturabie port.Type: ApplicationFiled: October 5, 2007Publication date: January 7, 2010Inventor: Joshua B. Stopek
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Device for connection between a receptacle and a container and ready-to-use assembly comprising same
Patent number: 7628779Abstract: The invention concerns a connection device comprising a base (10) adapted to be mounted on a receptacle (2) and forming a sliding sleeve (15) for a piston (16) which moves or forms a hollow needle (16), an annular skirt (20) for locking the base plate (10) in snap-on configuration on the neck (4), and a cap (30) designed to isolate the plate (10) and/or the piston (16) from ambient atmosphere. The cap (30) is provided with at least one protuberance (33) designed to be engaged in the internal volume (V) of said skirt (20), said protuberance (33) extending radially relatively to a central axis (X-X?) of the cap (30) over a distance (R33) greater than the minimum distance (R25) between said central axis (X-X?) and an edge (23) of the opening (O?) providing access to the internal volume (V) of said skirt. The protuberance remains integral with the rest (31a) of the cap when the latter is removed from the device.Type: GrantFiled: February 19, 2003Date of Patent: December 8, 2009Assignee: BiodomeInventor: Antoine Aneas -
Patent number: 7617929Abstract: A structure for mixing different materials in a pouch container includes a spout main body provided with a spout hole through which mixture of first and second materials is exhausted. A cap is removably coupled on an outer portion of the spout hole. The first material is stored therein. A seal member is coupled to a lower end of the tube portion.Type: GrantFiled: November 9, 2004Date of Patent: November 17, 2009Inventors: Jeong-Min Lee, Seong-Jae Lee
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Publication number: 20090264829Abstract: A sheath (1) is disclosed which is suitable for covering the needle of a syringe (2). The sheath (1) includes a filter (3) which projects partially from the end of the sheath to aid the drawing of liquid into the syringe. It is intended that the needle and/or syringe are sold fitted with the sheath (1) so that there is no need to expose the needle until the user is ready for injection. The invention includes a blister pack (12 FIG. 4) which includes a ready assembled syringe, a mixing pan and paraphernalia for the preparation of the solution to he injected.Type: ApplicationFiled: December 14, 2005Publication date: October 22, 2009Inventors: Nigel Harris, Nicholas John Stratton Davis
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Publication number: 20090264854Abstract: The invention provides container systems, kits and methods for peritoneal dialysis (PD) solutions. Such a system, for example, includes a first compartment that contains a PD osmotic agent and a second compartment that contains a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. The invention provides, in other aspects, such systems, kits and methods that provide protective structure which inhibits breaking of a seal prior between the second compartment and an outlet of the system, prior to breaking of a seal between the first and second compartments.Type: ApplicationFiled: April 14, 2009Publication date: October 22, 2009Applicant: Fresenius Medical Care Holdings, Inc.Inventors: Lynn E. Jensen, Spencer Clark, Olli Tuominen, Jay M. Lan
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Publication number: 20090264830Abstract: The invention relates to a kit for parenteral administration of drugs, particularly a kit for the infusion of those medicaments dissolved in solvents that extract toxic components from PVC, which is also suitable for the infusion of highly active medicaments, said kit ensuring a safe administration both for the patient and for healthcare staff.Type: ApplicationFiled: September 29, 2006Publication date: October 22, 2009Applicant: INFA S.A.Inventors: Flavio Villani, Paolo Magri
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Patent number: 7594578Abstract: A container for storing a liquid component of bone cement. The container includes a flexible film sealed about its periphery to define a cavity. The cavity has a first layer, a second layer, and a vinyl barrier layer between the first layer and the second layer. The cavity is operable to store the liquid component of bone cement.Type: GrantFiled: January 26, 2005Date of Patent: September 29, 2009Assignee: Biomet Manufacturing Corp.Inventors: Daniel B. Smith, Robert M. Ronk, John M. McDaniel, Jeffrey L. Colbert
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Publication number: 20090234317Abstract: A pouch for mixing and dispensing a composition including a pouch body and a port body. The pouch body includes opposing, first and second major flexible walls sealed to one another along respective peripheries thereof to define an internal chamber and a pouch perimeter. The pouch body has a C-like shape. The port body projects from the first wall and is fluidly open to the internal chamber. With this configuration, various components, such as a powder component and a liquid component, can be mixed by a user's hand(s) in pressing the walls in a kneading fashion, with the resultant composition being dispensed through the port body. In some embodiments, the pouch is provided to a user with a powder component pre-loaded in the internal chamber.Type: ApplicationFiled: March 13, 2008Publication date: September 17, 2009Inventor: Lissa M. Navarro
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Publication number: 20090221984Abstract: An apparatus for providing therapeutically effective mixtures of buffered lidocaine (with and without epinephrine) while simultaneously increasing the shelf life, having a two-chambered medicine vial, in which one chamber isolates up to 20 ml of a lidocaine solution (1% with or without epinephrine) and the other chamber isolates up to 2 ml of sodium bicarbonate (8.4%), with a fracturable wall therebetween such that the wall is fractured by bending or twisting, for mixing the lidocaine and sodium bicarbonate to create a buffered lidocaine for administration in therapeutically effective amounts, and further comprising stopper means, like a rubber stopper, for the insertion of a syringe for extraction of the mixture for administration. Also shown is a method for isolating the components for shelf life and providing mixing for an effective composition.Type: ApplicationFiled: March 3, 2008Publication date: September 3, 2009Inventors: Akram Girgis, Steve Thuss
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Publication number: 20090221987Abstract: The present invention is generally directed to a system and method for cleansing mucus and in particular, removing mucus from the nasal cavity, mouth, and throat. The sinus and throat cleansing kit includes packets of dry saline, packets of dry salt, a spoon for mixing the dry saline and dry salt with water to produce a saline solution and salt solution, a pot for pouring the saline solution into a nostril of the user cleansing a nasal cavity of mucus, a container lid for pouring the salt solution into the mouth of the user cleansing a mouth and throat of mucus, and a container for collecting saline solution, salt solution, and mucus. The sinus and throat cleansing kit provides a clean and portable way to remove mucus, bacteria, and other viruses of the throat.Type: ApplicationFiled: February 29, 2008Publication date: September 3, 2009Inventor: Syeda J.Z. Mansur
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Publication number: 20090216184Abstract: A drug storage and delivery device (1) comprising a reservoir (2) containing a liquid, a vial (3) containing a dry drug, such as a lyophilized drug, means (6) for forcing the liquid from the reservoir (2) to the vial (3), via an established fluid connection, and locking means adapted to prevent the means (6) for establishing a fluid connection from re-establishing a previously disconnected fluid connection between the reservoir and the vial. Thereby the dry drug is reconstituted, and the forcing means (6) may subsequently be used for forcing reconstituted drug out of the device (1). The reservoir (2), the vial (3), the fluid connection and the forcing means (6) may form an at least substantially integral unit. This is an advantage because the number of steps needed to be performed by the user is reduced, the risk of contamination is reduced, the risk of incorrect reconstitution and dosage is reduced, and the device is easy to operate, e.g. using just one hand.Type: ApplicationFiled: February 26, 2007Publication date: August 27, 2009Applicant: Novo Nordisk A/SInventors: Bo Radmer, Gunner Sie, Morten Revsgaard, Poul Larsen, Per Valentin Nielsen
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Publication number: 20090209935Abstract: It is an object of the resent invention to provide a multi-chamber container that has a weak seal portion having an increased joining strength and being easy to be opened when in administration of medicine, and that is provided at low cost. The multi-chamber container includes a medicine accommodation chamber 1, a diluting solution chamber 3 jointed to one side of the medicine accommodation chamber 1 via a partitioning weak seal portion 2, an unoccupied chamber 5 having a port 6 and joined to an opposite side of the medicine accommodation chamber 1 via a discharging weak seal portion 4, a film member 7 attached to the medicine accommodation chamber 1 for increasing a joining strength of each of the discharging weak seal portion 2 and the discharging weak seal portion 4, the discharging weak seal portion 4 having an easy-to-open portion 8 that enables the discharging weak seal portion 4 to easily opened therethrough.Type: ApplicationFiled: March 1, 2007Publication date: August 20, 2009Inventors: Fujio Inoue, Isamu Tateishi, Tatsuro Tsuruoka, Akihito Togawa
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Publication number: 20090204098Abstract: A flexible multicompartment container provided for storage and mixing together of a at least a first and a second single solution. Each single solution is stored in a separate compartment (1, 2) of the container. The compartments are separated by means of seals (5, 6) rupturable by manipulation of the container to thereby mix the contents together in a mixing compartment for delivery. The first compartment (1) is filled to a first filling degree, FD1, and the second compartment is filled to a second filling degree, FD2. The first filling degree is larger than the second filling degree. The filling degree in the mixing compartment, FDMC, is larger than the filling degree in the second compartment.Type: ApplicationFiled: October 16, 2006Publication date: August 13, 2009Inventors: Anders Wieslander, Peder Flank, Petra Ahl
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Publication number: 20090182301Abstract: The invention relates to a double chamber container for holding and combining two separate components, at least one of which is liquid, comprising a cylindrical body (15) with a closure (20, 60) at each of the two ends (5, 70) of the body (15), an upper closure (60) at the liquid component end and a lower closure (20) at the solid component end, and a separating stopper (40) in the cylindrical body (15) as a seal between the two chambers (30, 50), the separating stopper (40) having a height H and the upper closure (60) at the liquid component end being movable by the application of pressure, and comprising on its underside a hollow needle (45) with a length L having at least one opening (42) which is provided at the end opposite the tip, where H <L.Type: ApplicationFiled: March 18, 2009Publication date: July 16, 2009Inventors: Stefan Bassarab, Alexander Bauer, Nicole Denkinger, Patrick Garidel, Markus Hemminger, Hans-Joachim Kern, Andreas Langer, Ingo Presser
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Patent number: 7559921Abstract: A vacuum device for removing a lodged mass or bolus from the throat of a choking victim. The device includes a pump for creating a vacuum chamber communicating with a mouthpiece having a frangible membrane. A resilient striker fractures the membrane to generate a substantially instantaneous vacuum to the mouthpiece to dislodge the mass. In one embodiment, the membrane is substituted by a manually displaceable sealing member, which is resealed after use of the device by movement of a vacuum-generating plunger.Type: GrantFiled: October 24, 2005Date of Patent: July 14, 2009Inventors: James T. DeLuca, Paul V. DeLuca
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Publication number: 20090177179Abstract: The invention relates to a disposable packaging system (2) for storing and dispensing multi-component materials (6), wherein the disposable packaging system (2) has a rigid housing (5) which is separated by films (8) into at least two regions for storing and mixing multi-component materials (6), and wherein the films (8) are arranged as separating membranes (9) in the housing (5) and have weak points (10) which tear open on contact with a sharp object (11) so that the materials (12, 13) separated by the separating membranes (9) mix together in the housing (5).Type: ApplicationFiled: March 30, 2007Publication date: July 9, 2009Applicant: S&C Polymer, Silicon-und Composite Spezialiten GmbInventor: Juergen Engelbrecht
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Patent number: 7544191Abstract: A formed, filled, and sealed container, access port and method for establishing fluid flow from the container to an administrative set is provided. The container is collapsible and has an inlet and an outlet. A hollow port is sealed to the container and a perforator inside the port pierces and becomes embedded in the container. Solution in the container is withdrawn into the port. A line attached to the port and an administrative set further establishes flow between the container and the administration set. The port may be operated with a single-hand to establish fluid flow from the container to the administrative set. After the perforator is embedded in the container, a lock on the port prevents the perforator from removal from the container. Activation of the lock produces an audible and/or visible notification.Type: GrantFiled: October 22, 2002Date of Patent: June 9, 2009Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Francesco Peluso, Patrick Balteau, Eric Hénaut, Barbara Mandard, Jean-Pierre Hartman, Vincent Houwaert, Giorgio Cantoni, Silvano Sforacchi
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Patent number: 7527619Abstract: A flexible non-PVC, non-DEHP container or bag for medical fluids has a container body formed of a multiple layer polyolefin film. The container has one or more ports equipped with a polyolefin fill tube and port closure assembly. The container has a low moisture vapor transmission rate.Type: GrantFiled: June 28, 2006Date of Patent: May 5, 2009Assignee: Hospira, Inc.Inventors: John Domkowski, Richard E. Burg, Glenn A. Caspary, Marc M. Daniels, Mark I. Ostler, Joseph Pasini, Stanley F. Pytel, John Sergot, Sheldon M. Wecker
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Patent number: 7510548Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.Type: GrantFiled: May 2, 2006Date of Patent: March 31, 2009Assignee: ICU Medical, Inc.Inventor: Thomas F. Fangrow