Materials Mixed Within Container Patents (Class 604/416)
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Patent number: 8182449Abstract: The invention relates to a kit for parenteral administration of drugs, particularly a kit for the infusion of those medicaments dissolved in solvents that extract toxic components from PVC, which is also suitable for the infusion of highly active medicaments, said kit ensuring a safe administration both for the patient and for healthcare staff.Type: GrantFiled: September 29, 2006Date of Patent: May 22, 2012Assignee: INFA, S.A.Inventors: Flavio Villani, Paolo Magri′
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Patent number: 8173066Abstract: The invention relates to a method for inactivating pathogens such as bacteria and viruses and/or leucocytes in thrombocyte concentrations by irradiation in flexible containers with ultra-violet light using agitation. The blood product is packaged in a flexible bag to permit the intermixing of the fluid by agitation (tilting, rotation, translation). This is also promoted by the filling of the bag to a maximum 30% of the filling capacity.Type: GrantFiled: December 21, 2006Date of Patent: May 8, 2012Assignees: Forschungsgemeinschaft der DRK Blutspendedienste e.V., Maco Pharma S.A.Inventors: Harald Mohr, Wolfram H. Walker
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Patent number: 8172823Abstract: A port assembly includes a valve housing with an inlet opening, a valve disposed in the valve housing to control access through the inlet opening, and a base joined to the valve housing and having a bore therethrough. The bore has a closed end defined by a frangible barrier, and a pushrod is disposed in the bore between the valve and the frangible barrier, axial movement of the pushrod causing rupture of the frangible barrier. The port assembly may be used in a fluid container that includes a receptacle for retaining a fluid, and at least one conduit in communication with the receptacle. The at least one conduit is defined, at least in part, by a port assembly.Type: GrantFiled: July 3, 2008Date of Patent: May 8, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Georges Rondeau, Gianni Di Stefani, Eric J. Henaut, Steven C. Jepson, Mark C. Perry, James B. Winje, Richard F. Chamernik
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Patent number: 8172824Abstract: An apparatus for combining under sterile conditions a liquid component held in a first container and a solid or liquid component held in a second container is provided. In one embodiment, two hollow bodies for receiving the two containers are provided, the two hollow bodies being arranged one within the other and being slidable relative to one another in a guided manner in the longitudinal direction. A cannula holder forms a pot-shaped structural unit with the first hollow body. Alternatively, the cannula holder is provided with at least one cannula. The cannula holder and the first hollow body may be separate components, in which the cannula holder is pot-shaped.Type: GrantFiled: August 30, 2002Date of Patent: May 8, 2012Assignee: CSL Behring GmbHInventors: Thomas Pfeifer, Dietmar Palm, Michael Becker, Michael Seipp, Rainer Wabnegg
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Patent number: 8163361Abstract: A pliable plastic film according to the present invention comprises a heat sealable sealing layer, wherein the sealing layer is made of a mixture of a propylene-?-olefin random copolymer having a crystalline melting point Tm of 135 to 145° C. and a polypropylene (PP) homopolymer having a crystalline melting point Tm of higher than 160° C.Type: GrantFiled: March 23, 2010Date of Patent: April 24, 2012Assignee: Otsuka Pharmaceutical Factory, Inc.Inventors: Isamu Tateishi, Hitoshi Mori
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Patent number: 8162917Abstract: A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage.Type: GrantFiled: March 18, 2009Date of Patent: April 24, 2012Assignee: Onpharma, Inc.Inventors: Matthew J. Stepovich, Michael I. Falkel
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Patent number: 8156971Abstract: An apparatus for the handling of hazardous fluids includes a collection vessel, a collection vessel connector, a dose control connector, a unit dose container, a delivery control connector, and a delivery site access device. The collection vessel contains the fluid prior to dispensing, the unit dose container contains a predetermined amount of the fluid for dispensing, the delivery site access device provides access to an intended delivery site, and the connector attaches pieces of the apparatus to one another. The method of the invention allows needle-free connections to be made for the apparatus, using a predetermined arrangement of the pieces of the apparatus, and in one embodiment, employs deformable elastomeric valves capable of creating a decreased pressure at a valve surface, so that upon closure of said valves, a fluid on the surface on the valves is withdrawn within the connector.Type: GrantFiled: March 17, 2010Date of Patent: April 17, 2012Assignee: Cardinal Health 414, LLC.Inventor: Jerry Costanzo
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Patent number: 8128612Abstract: The present invention relates to unitary bottle for injection, more particularly, to a unitary medicine bottle having an integral structure where a medicine container is easily connected with a plastic container including a solution at a completely sterilized state so that powdered, freeze-dried or liquid medicine is mixed with the solution with one touch for a short time. The unitary medicine bottle for injection according to the present invention comprises: a plastic container equipped with a coupling member connected with a medicine container at one end and a releasing member for releasing a liquid medicine to be at the other end; a protection cap integrally formed with the coupling member to accept the medicine container; and a flue needle which moves forward in a direction of the medicine container and perforates a stopper of the medicine container and is inserted in the coupling member connecting the plastic container with the medicine container.Type: GrantFiled: June 28, 2006Date of Patent: March 6, 2012Assignee: BNCP CorporationInventor: Gi-Bum Oh
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Publication number: 20120053555Abstract: A reconstitution assembly includes a housing including a lower sleeve and an upper sleeve, including a first container and a second container disposed vertically opposite the first container. A transfer set assembly is disposed within the housing between the first container and the second container. The transfer set assembly includes an upper spike housing and a lower spike housing, with a flow path defined through the upper spike housing and the lower spike housing. The transfer set assembly is configured to access contents of the first container and then upon the activation of a triggering mechanism, create a fluid pathway between the first container and the second container. The triggering mechanism includes trigger fingers which ensure the transfer set assembly sequentially accesses the contents of the first container before accessing the contents of the second container. The disposition of the first container activates the triggering mechanism.Type: ApplicationFiled: August 25, 2011Publication date: March 1, 2012Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.Inventors: Scott Ariagno, Frederick Charles Houghton, II, Daniel E. Roush
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Patent number: 8109917Abstract: Disclosed is a dispenser having a first chamber containing a first fluid and a second chamber containing a second material. Each chamber has screw threads that are selectively joinable so that the first and second chambers are twistable relative to one another. The first chamber includes an open top end that is, before use, covered with a breakable membrane. A breaker ring is located within the second chamber and is configured to break the breakable membrane when the dispenser is transitioned between an extended position and a compact position. In the compact position with the breakable membrane broken, the first fluid and second material form a mixture that can be dispensed via an opening in an openable tip.Type: GrantFiled: January 18, 2010Date of Patent: February 7, 2012Inventors: Rourke M. Yeakley, Charles Leslie Floyd, Jr.
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Patent number: 8109902Abstract: Improvements are provided for a syringe-to-syringe mixing system to improve the mixing characteristics of the system. In one embodiment, a mixing apparatus includes opposite fittings for mounting to a pair of syringes. The mixing apparatus defines a fluid passageway therethrough and includes a flow modifying element disposed within the passageway. The flow modifying element is configured to increase the flow velocity, disrupt the fluid flow or introduce turbulence into the fluid flow between the two syringes. In another embodiment, a nozzle element is disposed within the tip of the syringe, the element configured to increase the fluid flow therethrough. The nozzle element can be a nozzle insert removably mounted within the tip, or an integrally formed nozzle within the tip.Type: GrantFiled: October 20, 2009Date of Patent: February 7, 2012Assignee: Spine Wave, Inc.Inventors: Lance Middleton, Scott Reed, Jared Walkenhorst
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Patent number: 8088118Abstract: A system and method for transferring a fluid from a first container to a second container, the system comprising a first container (112) having a fluid (126) therein, the first container being sealed by a septum (124) and a piston (122), the second container being sealed at its mouth by a pierceable septum (132) and having a plunger (130) at the opposite end, a moveable needle shuttle (116) having first (144) and second (146) piercing ends, the arrangement being such that upon advancement of the first container with respect to the second container, a second one of the piercing ends (144) is adapted to pierce plunger (130) of the second container and a first piercing end (146) being designed to pierce the septum (124) of the first container.Type: GrantFiled: June 13, 2008Date of Patent: January 3, 2012Assignee: Duoject Medical Systems Inc.Inventors: David L. Reynolds, Daniel MacDonald, Julie Trepanier, Steven Raymond, Caroline Lavoie
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Patent number: 8088117Abstract: Methods, systems, and apparatus for a fill port for a flexible container such as a flexible self supporting dewatering or marine structure. The container includes a flexible material having at least one opening and a fill port having an inner port body and an outer port body. At least one face of the inner and/or outer port body has a plurality of cellular surfaces with cavities that do not extend through the inner and/or outer port body on which they are positioned. The cavities receive a portion of the flexible material when the inner port body, the flexible material, and the outer port body are secured together and in use, thus minimizing stresses on the flexible material surrounding the fill port by equally distributing the forces acting on this material during the filling stage and thus reducing the risk of tears or failure to the flexible container.Type: GrantFiled: October 25, 2005Date of Patent: January 3, 2012Assignee: Nicolon CorporationInventors: Thomas Charles Stephens, Edward Warren Trainer
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Publication number: 20110311602Abstract: Microbial growth inhibiting solutions and methods of employing the microbial growth inhibiting solutions in flushing and coating medical devices are disclosed. In alternative embodiments, the microbial growth inhibiting solutions include combinations of a chelating agent with a C4-C9 carboxylate antimicrobial agent, for example, such as n-octanoic acid. Methods of using these microbial growth inhibiting solutions for coating a medical device and for inhibiting catheter infection are also disclosed.Type: ApplicationFiled: August 31, 2011Publication date: December 22, 2011Applicant: Organic Medical Ventures, L.L.C.Inventors: Stanley L. Mills, Jacqueline L. Mills, Robert D. Maurer, Gary L. Rayburn, Marvin A. Cuchens
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Patent number: 8075545Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.Type: GrantFiled: August 1, 2008Date of Patent: December 13, 2011Assignee: Hospira, Inc.Inventors: Yei F. Moy, Stanley F. Pytel, John S. Ziegler, Jesse C. Darley, Douglas S. Rodenkirch
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Publication number: 20110301564Abstract: A liquid component collecting device capable of more easily collecting a liquid component. A liquid component collecting device(100) is provided with: a flexible cylindrical liquid component storage container (21) having an opening at one end thereof; a cylindrical first housing container (22) for housing the liquid component storage container (21) and having an opening at one end thereof; and a first cap (23) connected to the opening in the liquid component storage container (21) and fitted to the opening in the first housing container (22). A pressure regulating space (26) independent of the internal space of the liquid component storage container (21) is formed between the outer side of the liquid component storage container (21) and the inner side of the first housing container (22).Type: ApplicationFiled: January 22, 2010Publication date: December 8, 2011Inventors: Masayoshi Omori, Seishin Tanaka, Yasunori Okamoto
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Patent number: 8070740Abstract: Methods and systems for providing an improved apparatus and packaging system to more expeditiously hydrate or reconstitute medical grafts and to effectively and uniformly seed the medical grafts with biological components and cultured cells. The systems generally comprise a container comprising entry port, at least one substrate cavity, and top, side and bottom walls defining an inner surface. The entry port is configured to receive the biological solution. The cavity is in communication with the entry port and includes the porous substrate maintained under negative pressure. The container volume is substantially the same as a volume of the porous substrate. The side and bottom walls are configured to promote a laminar flow of the biological solution received through the entry port.Type: GrantFiled: May 30, 2008Date of Patent: December 6, 2011Assignee: Alphatec Spine, Inc.Inventors: Amit Govil, Christian Gamboa
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Patent number: 8063265Abstract: A hydrogel having a floatability where from 40% to 90% of a solution and/or suspension to be thickened are thickened starting from the surface of the liquid and the rest of the solution and/or suspension to be thickened is thickened starting from the bottom of the container, a process for preparing the hydrogel and also its use for absorbing blood and/or body fluids, especially in hygiene articles, or for thickening aqueous solutions and/or suspensions, especially for thickening medical wastes.Type: GrantFiled: October 28, 2004Date of Patent: November 22, 2011Assignee: BASF AktiengesellschaftInventors: Martin Beck, Volker Frenz, Anna Kowalski, Elisabeth Selzer, Ernst Jürgen Bauer, Harald Keller, Bernhard Steinmetz
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Publication number: 20110282317Abstract: A container for accommodating different injection medicines comprises a first vessel, a second vessel and a partition disk. First vessel is an integral hollow cylinder sandwiched between a pair of intercommunicatable top surface and bottom surface. Second vessel of integral hollow cylinder includes a first holding compartment therein encompassed by an open top surface, a closed bottom surface and a sidewall. Partition disk is padded under the bottom of the first vessel. Partition disk and lower section of first vessel are inserted into upper section of second vessel. Thereby, different injections can be temporarily held in separated compartments respectively without intermixing. When injection administration is required, blending procedure is well hermetically finished in the vial without any syringe needle. Thereby, not only entire blending procedure meets aseptic requirement, but also accidence for the healthcare personnel being pierced by such syringe needle is completely eliminated.Type: ApplicationFiled: July 28, 2011Publication date: November 17, 2011Inventor: Kuo-Cheng Wu
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Publication number: 20110282316Abstract: A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage. By delivering a buffer with a precisely controlled pH, accurate buffering of the anesthetic can be achieved.Type: ApplicationFiled: November 11, 2010Publication date: November 17, 2011Applicant: Onpharma Inc.Inventors: Matthew J. Stepovich, Michael I. Falkel, Harry Nguyen
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Publication number: 20110276021Abstract: A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.Type: ApplicationFiled: July 18, 2011Publication date: November 10, 2011Inventors: Vincent J. Sullivan, Ge Jiang, Matthew S. Ferriter, Kenneth G. Powell, P. Spencer Kinsey, Carl R. Sahi, John M. Polidoro
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Patent number: 8052667Abstract: The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis.Type: GrantFiled: September 7, 2005Date of Patent: November 8, 2011Assignee: Velico Medical, Inc.Inventors: Keith Rosiello, Henrik Clausen
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Publication number: 20110270220Abstract: A device for administering a therapeutic substance includes a sealed package and an administration assembly. The sealed package includes a collapsible compartment containing the substance. The administration assembly includes a dispenser that is in fluid communication with the substance. At least one compression member is movable by linear actuation to progressively collapse the collapsible compartment and urge the therapeutic substance through the dispenser.Type: ApplicationFiled: March 3, 2011Publication date: November 3, 2011Applicant: AKTIVPAK, INC.Inventor: Amir Genosar
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Publication number: 20110270223Abstract: A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.Type: ApplicationFiled: July 18, 2011Publication date: November 3, 2011Inventors: Vincent J. Sullivan, Ge Jiang, Matthew S. Ferriter, Kenneth G. Powell, P. Spencer Kinsey, Carl R. Sahi, John M. Polidoro
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Patent number: 8029747Abstract: Pressure equalizing device comprising a fluid container for attachment to a receptacle such as a vial to permit pressure equalization between the fluid container and the receptacle. The pressure equalizing device comprises a flow channel that is arranged to provide fluid communication into or out of the fluid container when the pressure equalizing device is attached to the receptacle. The pressure equalizing device also comprises a fluid inlet that contains a one-way valve that permits fluid to flow into the fluid container via said fluid inlet and that prevents fluid from flowing out of the fluid container via said fluid inlet and filter-receiving means that are arranged to permit fluid flowing into or out of the fluid container to be filtered when the filter-receiving means comprises a filter.Type: GrantFiled: June 13, 2007Date of Patent: October 4, 2011Assignee: Carmel Pharma ABInventor: Elisabet Helmerson
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Patent number: 8025915Abstract: A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.Type: GrantFiled: January 4, 2007Date of Patent: September 27, 2011Assignee: Schott AGInventors: Daniel Haines, Luis Burzio, Matthias Bicker, Robert Hormes, Horst Koller, Jasmina Buki, Hartmut Bauch, Manfred Lohmeyer
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Publication number: 20110230856Abstract: A fluid management system for transferring fluid, the system including a connector component comprising a first end and an opposite second end, a first syringe with a distal end that is removably attachable to the first end of the connector component, and a second syringe with a distal end that is removably attachable to the second end of the connector component.Type: ApplicationFiled: August 21, 2009Publication date: September 22, 2011Inventors: Matthew R. Kyle, Kyle W. Swartout
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Publication number: 20110196334Abstract: A container for re-suspending sedimented medicament comprises a reservoir for containing a suspension of particles in a liquid, a dispensing portion, and a sealing portion. The sealing portion is arranged to be in fluid communication with the reservoir via an orifice. The orifice is positioned between the dispensing portion and the sealing portion, and allows a turbulent flow of the liquid from the reservoir into the sealing portion to enable re-suspension of particles that have sedimented out of the liquid in the sealing portion.Type: ApplicationFiled: June 27, 2006Publication date: August 11, 2011Applicant: NORTON HEALTHCARE LIMITEDInventor: Martin Oliver
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Patent number: 7985212Abstract: The invention provides container systems, kits and methods for peritoneal dialysis (PD) solutions. Such a system, for example, includes a first compartment that contains a PD osmotic agent and a second compartment that contains a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. The invention provides, in other aspects, such systems, kits and methods that provide protective structure which inhibits breaking of a seal prior between the second compartment and an outlet of the system, prior to breaking of a seal between the first and second compartments.Type: GrantFiled: July 27, 2007Date of Patent: July 26, 2011Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Lynn E. Jensen, Spencer Clark
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Publication number: 20110178494Abstract: Disclosed is a dispenser having a first chamber containing a first fluid and a second chamber containing a second material. Each chamber has screw threads that are selectively joinable so that the first and second chambers are twistable relative to one another. The first chamber includes an open top end that is, before use, covered with a breakable membrane. A breaker ring is located within the second chamber and is configured to break the breakable membrane when the dispenser is transitioned between an extended position and a compact position. In the compact position with the breakable membrane broken, the first fluid and second material form a mixture that can be dispensed via an opening in an openable tip.Type: ApplicationFiled: January 18, 2010Publication date: July 21, 2011Inventors: Rourke M. Yeakley, Charles L. Floyd, JR.
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Patent number: 7980243Abstract: A cartridge for propellant-free administration of a liquid pharmaceutical composition by inhalation includes: an elongate displacing device including an upper end and a lower end, the lower end for at least partial insertion into a container; a cartridge chamber disposed at the lower end of the displacing device and operable store a pharmaceutical formulation, the cartridge chamber including at least one pierceably sealed opening; and a cannula guide extending from the upper end of the displacing device to the cartridge chamber, wherein insertion of a cannula through the guide pierces the sealed opening and releases the pharmaceutical formulation into a liquid solvent in the container to form the liquid pharmaceutical composition.Type: GrantFiled: June 7, 2007Date of Patent: July 19, 2011Assignee: Boehringer Ingelheim Pharma GmbH & Co., KGInventor: Dieter Hochrainer
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Patent number: 7972321Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial includes a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial includes a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.Type: GrantFiled: March 19, 2008Date of Patent: July 5, 2011Assignee: ICU Medical, IncInventor: Thomas F. Fangrow
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Publication number: 20110160693Abstract: A medication-containing container includes a container body having at its front end side a mouth section through which liquid can enter and exit the container body and made of a flexible material, and also with a medication contained in the container body and dissolved by the liquid flowing into the container body. In the medication-containing container, the container body has two flat sections facing each other with a gap therebetween in an initial state in which the container body is not filled with liquid, a frame section on the outer peripheries of the flat sections, and an easily deformable section interconnecting at least either of the pair of flat section and the frame section. When the container body is filled with liquid, the easily deformable section deforms to separate the flat sections from each other, increasing the gap between the flat sections to increase the volume of the container body.Type: ApplicationFiled: July 2, 2009Publication date: June 30, 2011Applicant: Terumo Kabushiki KaishaInventor: Masaomi Imai
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Publication number: 20110144613Abstract: A flexible container receives a liquid material, which is freeze-dried in situ within the flexible container. A gas permeable material that is separate from the flexible container provides gas transport for sublimation during drying and lyophilization. The gas permeable portion of the system can be isolated and removed from the flexible container post-lyophilzation The freeze-dried material is stored in the flexible container until administration is necessary. The flexible container receives a reconstituting liquid for mixing with the freeze-dried material, and conveys the reconstituted freeze-dried material from the flexible container for administration to an individual.Type: ApplicationFiled: August 11, 2009Publication date: June 16, 2011Applicant: HEMCON MEDICAL TECHNOLOGIES, INC.Inventors: Clinton B. Pepper, Simon J. McCarthy, Lisa A. Buckley, Eric K. Meyer
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Publication number: 20110137280Abstract: The present invention relates to a connector for a replaceable container to be used in a medical machine, which is comprised by at least a body, the inner side of which is traversed by inlet and outlet tubes extending from within such container towards an outer side of the connector, wherein said tubes separately extend leading to two laterally spaced-apart apertures that are removably attachable to a mounting means and supplementary connection of said machine.Type: ApplicationFiled: August 4, 2009Publication date: June 9, 2011Inventors: Juan Miguel Angel Ramella, Leonardo Franco Farace
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Patent number: 7951109Abstract: A storage and dispensing cap for a liquid receptacle having a cap body storage chamber for use with a receptacle such as a bottle, pouch or intravenous bag that is used to store a liquid for use with a syringe that is inserted into the receptacle for drawing the liquid contents into the syringe. A liquid, powder or capsule in the cap body chamber is mixed into the liquid receptacle for use with the syringe. A sleeve penetrator is mounted inside said cap body chamber and is sized in length to permit rupture of the bottom floor of said cap body chamber when manually depressed for dispensing whatever material is placed inside said cap body chamber and sleeve penetrator into said syringe bottle. An open passage from the cap body to the inside of the receptacle is provided once the storage chamber is ruptured by manually depressing the penetrator to allow the syringe needle end to be inserted into the liquid receptacle.Type: GrantFiled: September 22, 2006Date of Patent: May 31, 2011Assignee: Andeboh Holdings, FLPInventor: Michael R. Anderson
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Patent number: 7938816Abstract: The invention relates to a medical bag which is intended for the infusion of a medicament by means of gravity. The inventive bag comprises: at least two compartments, namely a first compartment (1) containing a medicament in the form of a solution and a second compartment (2) containing a rinsing solution; and means for separating/communicating the compartments, which prevent the rinsing solution from automatically entering the medicament compartment except at the end of the infusion period. The rinsing solution ends the infusion, by rinsing the medicament bag and the infusion line, such as to prevent any risk of contamination or leakage of residual medicament from the bag or line.Type: GrantFiled: April 8, 2010Date of Patent: May 10, 2011Assignee: Laboratoire AguettantInventor: Pierre Frezza
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Patent number: 7935101Abstract: The present invention relates to a multi-chamber medical bag, which is capable of obtaining a positive mixture of medicines, prior to the discharge thereof. A weak seal 24 is provided for dividing the space inside the medical bag 10 into the left-handed and right-handed partitions 26-1 and 26-2. The weak seal 24 has a first portion 24-1 extending between the partitions 26-1 and 26-2 and a bifurcated adjacent to and faced with an outlet port 12. Additional strong seals 30-1 and 30-2 are arranged on both sides of the second portion 24-2 and extend at right angle to the first portion 241 toward the strong seal 14 at the outer periphery of the medical bag. When the partition 26-1 or 26-2 is pressed, the resultant inflated deformation of the medical bag is mainly directed to the first portion 24-1 due to the existence of the additional strong seals 30-1 and 30-2, which allows the last portion to be separated, resulting in a mixing of the medicines in the partitions 26-1 and 26-2.Type: GrantFiled: May 6, 2009Date of Patent: May 3, 2011Assignee: Ajinomoto Co., Inc.Inventor: Yasuhiro Muramatsu
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Publication number: 20110097372Abstract: The subject invention provides novel and highly effective methods and devices for convenient and effective wound irrigation.Type: ApplicationFiled: October 24, 2010Publication date: April 28, 2011Inventor: Paul J. Rucinski
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Publication number: 20110092953Abstract: A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These pieces are sized so that, when wet, they are capable of flowing through a cannula and/or reduced-diameter syringe tip. The pieces are placed into a syringe and wetted, say with a morphogenic solution, and optionally mixed with a bulking material, which is similarly sized to fit through the cannula. The thoroughly mixed and wetted product forms a viscous aggregate which may then be injected into the patient at the target site.Type: ApplicationFiled: December 23, 2010Publication date: April 21, 2011Applicant: WARSAW ORTHOPEDIC, INC.Inventors: Neil Beals, Jeffrey L. Scifert, Scott D. Boden
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Publication number: 20110082427Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.Type: ApplicationFiled: October 6, 2010Publication date: April 7, 2011Applicant: Regents of the University of MinnesotaInventors: Jafar Golzarian, Lihui Weng
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Patent number: 7913720Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.Type: GrantFiled: October 31, 2006Date of Patent: March 29, 2011Assignee: FHT, Inc.Inventors: Dennis Tribble, Joel A. Osborne, Abdul Wahid Khan, Morris W. Wallace, Vaibhav Deshpande
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Publication number: 20110066130Abstract: The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.Type: ApplicationFiled: November 23, 2010Publication date: March 17, 2011Applicant: Travanti Pharma Inc.Inventors: Carter R. Anderson, Russell L. Morris
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Patent number: 7905873Abstract: A port assembly includes a valve housing with an inlet opening, a valve disposed in the valve housing to control access through the inlet opening, and a base having an outlet opening that is initially occluded by a membrane. A pivot is disposed within the base and has a cutting surface disposed within the base, the cutting surface rupturing the membrane at least in part as the pivot is pivoted about an axis between first and second positions. The port assembly may be used in a fluid container that includes a receptacle for retaining a fluid, and at least one conduit in communication with the receptacle. The at least one conduit is defined, at least in part, by the port assembly.Type: GrantFiled: July 3, 2008Date of Patent: March 15, 2011Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Georges Rondeau, Gianni Di Stefani, Eric J. Henaut
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Patent number: 7900659Abstract: A pressure-equalizing vial access device and method providing closed and sealed reconstitution of vial contents. A rigid container with a fixed internal volume is connected with a vent lumen extending into the vial. As pressure in the vial increases, the pressure is equalized with atmospheric pressure by varying the volume of a compartment within the rigid container. The compartment is formed with a volume control device that automatically varies the volume of the compartment in the rigid container to accommodate and equalize the pressure in the vial by increasing or decreasing the volume of the compartment. In one case the volume control device comprises a sliding disk and in another, a bladder that compresses with an increase in volume in the container and expands with a decrease.Type: GrantFiled: December 19, 2006Date of Patent: March 8, 2011Assignee: CareFusion 303, Inc.Inventors: Kenneth W. Whitley, John C. Phillips
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Patent number: 7900658Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.Type: GrantFiled: October 20, 2006Date of Patent: March 8, 2011Assignee: FHT, Inc.Inventors: Joel A. Osborne, Dennis Tribble, Abdul Wahid Khan, Morris W. Wallace, Roy A. Hughes, Jayson Lee Bender, Matt Valentine, Dexter Bautista, Jim Shafer
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Publication number: 20110054437Abstract: The invention provides a device (10) for conserving and extemporaneously preparing at least one active principle prior to administration, the device comprising: a body (12) that is constituted by at least one compartment for containing at least one volume of pharmaceutical solvent (22) that is less than 5 mL; a head (14) constituted by at least one compartment for containing at least one active principle (24), in particular a very small dose, and, in its top portion, by at least one dose-taking chamber (32) provided with a filter (40), the head (14) being capable of taking up a first position P1 for conservation, in which said head (14) is in its distal position relative to the body (12), and a second position P2 for preparation, in which said head (14) is in its proximal position relative to the body (12); at least one wall (16) separating the body (12) and the head (14); and rupture means (18) for rupturing said wall (16) so that the active principle (24) enters into contact with the solvent (22) and dissolType: ApplicationFiled: April 17, 2009Publication date: March 3, 2011Inventors: Philippe Perovitch, Tatiana Galperine
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Patent number: 7896860Abstract: A container for addition (co-infusion) of medicine to an infusion bag and aims to keep a positive sealed condition while preventing a number of parts from being increased and while maintaining a positive releasing of the sealed condition when an infusion process is carried out. A breakable lug 20 is integrally formed at a end of a port body 10 to which a soft container 80 for storing therein with a co-infusion liquid under a sealed manner, which lug 20 is able to be broken in order to obtain a release function. A rubber plug 98 of an infusion bag 90 is pierced by a needle body 11, while the port body 10 is press fitted into a straight bore of the needle body 11, so that the lug 20 is contacted with an opposed bottom wall of the needle body 11, resulting in at least partial breakage of the lug 20, thereby forming an opening 89 at the portion where the breakage is taken place, so that the medicine in the soft container 80 is transported (co-infused) into the infusion bag 90.Type: GrantFiled: September 17, 2007Date of Patent: March 1, 2011Assignee: Ajinomoto Co., Inc.Inventors: Kaoru Shimizu, Yasuhiro Muramatsu
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Publication number: 20110040249Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.Type: ApplicationFiled: August 12, 2010Publication date: February 17, 2011Inventors: JACQUELINE BENSON, JILL CARTON, MARK CUNNINGHAM, YEVGENIYA I. ORLOVSKY, ROBERT RAUCHENBERGER, RAYMOND SWEET
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Patent number: 7883499Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial includes a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial includes a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.Type: GrantFiled: March 7, 2008Date of Patent: February 8, 2011Assignee: ICU Medical, Inc.Inventor: Thomas F. Fangrow