With Separate Applicator For Material Or Separate Holder For Material Placed On Applicator Or In Wound Patents (Class 604/47)
  • Patent number: 10449346
    Abstract: An improved tattooing needle assembly and support assembly for the needle assembly are provided. The needle assembly includes a needle component extending through a main case into an aperture assembly. The needle component is configured to reciprocate between a stowed configuration, in which a tip of the needle component is positioned within the aperture assembly, and a deployed configuration, in which the tip extends beyond the aperture assembly. A tattooing machine causes the needle component to move to the deployed configuration while opposed magnets bias the needle component back towards the stowed configuration. Using a needle protection sleeve, the needle assembly can be removed from and/or installed onto a tattooing machine without requiring a user to come into direct contact with the needle assembly. By securing the needle protection sleeve to a support assembly, the removal and/or installation of the needle assembly becomes a one-hand operation.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: October 22, 2019
    Assignee: Painful Pleasures, Inc.
    Inventor: Zhao Juan
  • Patent number: 10252043
    Abstract: A device can be used for delivering a dose of a vaccine, a medicine, a medication, a drug, or a prescription. For example, this document describes a wearable vaccination device that plays an audible sound or a musical tune for distracting or entertaining a patient while an intradermal vaccine is delivered via the patient's skin. A control portion of the wearable vaccination device includes a processing unit, a rhythm producer that produces audible sounds to distract or entertain the patient, and an injection module that provides an intradermal injection using one or more microneedles.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: April 9, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kylash R. Chettiar, Vinutha Rajesh
  • Patent number: 9968767
    Abstract: The combination microarray patch for drug delivery and electrochemotherapy device is a medical device for delivering two separate pharmaceutical preparations to a patient, as well as providing electrostimulation for electroactive pharmaceuticals. A first pharmaceutical preparation is manually delivered into the patient through a first set of drug delivery needles. Similarly, a second pharmaceutical preparation is manually delivered into a patient through a second set of drug delivery needles. A desired electrical potential may then be selectively applied across first and second sets of electrotherapy needles for electroporation to facilitate delivery of the pharmaceutical preparations. The second pharmaceutical preparation may be a conjugate of the first for targeted drug delivery.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: May 15, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Sartaj Tabassum Hasan, Hamad A. Al-Lohedan
  • Patent number: 9616211
    Abstract: The invention relates to a device for inserting pigment into the skin comprising a roller head unit comprising 2 or more distal arms; a rotatable structure comprising needles extending therefrom, attached to said roller head unit between said distal arms; a tubular member attached to the proximal end of said roller head unit; an elastic element placed within the distal portion of the inner lumen of said tubular member; a pin placed within said tubular member proximal to said elastic element.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: April 11, 2017
    Assignee: NEW PERMANENT MAKEUP LTD.
    Inventor: Moshe Alul
  • Patent number: 9393395
    Abstract: A tattoo machine for oscillating a tattoo needle includes a main housing and a motor secured to the main housing. A needle bar member is movably secured to the main housing for linear oscillation relative thereto. A drive mechanism is operatively connected to an output shaft of the motor and to the needle bar member for translating rotary movement of the output shaft into linear oscillation of the needle bar member.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: July 19, 2016
    Inventors: Michael Chen, Wen Wei, Billy Chen
  • Patent number: 9227023
    Abstract: This device is a compressible chamber designed to inject a liquid medication through a plurality of needles. It is a self-contained, rapidly deployed device that replaces a classic syringe. It consists of a shallow chamber that is closed on one end and sealed on the other with a sliding elastomeric seal. A rigid ring slides up into the chamber that has multiple small double-ended needles mounted through the periphery of the ring perpendicularly so as to be able to perforate the seal of the chamber with the proximal end and simultaneously penetrate the subcutaneous tissues with the distal end thus allowing medication to flow from the chamber into the tissues when pressure is applied to the top of the chamber. The needles are also imbedded in, or juxtapose to a ring of compressible dye-containing material that serves to conceal the needles and provide demarcation of the area injected.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: January 5, 2016
    Inventor: Joseph Wayne Kraft
  • Publication number: 20140128802
    Abstract: The present invention relates to a device and method for a chemical applicator used applying chemicals to living organism's internal tissue, including the internal tissue of plants and animals, for organisms which reside on or in mediums such as land, air or water. The device of the present invention is predicated, in part, on the piercing elements being engageable with the chemical reservoir in order to effect the coating of the piercing elements with the chemical. Once coated, these piercing elements are then used to pierce the living organism's tissue such as plant tissue to deliver the chemical.
    Type: Application
    Filed: January 13, 2014
    Publication date: May 8, 2014
    Applicant: ARIANA HOLDINGS PTY LTD
    Inventor: Rad Omid
  • Patent number: 8696637
    Abstract: A transdermal patch that can easily deliver a controlled volume of a fluidic drug compound to skin is provided. More particularly, the patch contains a microneedle assembly that is configured to be placed in fluid communication with a drug delivery assembly. The microneedle assembly contains a support and a plurality of microneedles that extend outwardly from the support. The microneedles are formed with one or more channels of a certain dimension such that passive capillary flow drives a flow of the drug compound. The drug delivery assembly contains a reservoir for the drug compound that is in fluid communication with a rate control membrane that helps control a flow rate of the drug compound by modulating a pressure of the drug compound, downstream from the reservoir. A release member is also positioned adjacent to the microneedle and drug delivery assemblies. Prior to use, the release member acts as a barrier to the flow of the drug compound and thus inhibits premature leakage.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: April 15, 2014
    Assignee: Kimberly-Clark Worldwide
    Inventor: Russell F. Ross
  • Patent number: 8664280
    Abstract: A kit for forming a bioerodible composition is provided with a first aliquot portion of a reaction mixture having an aldehydic polymer solution, and a second aliquot portion of a reaction mixture having solids which include a cross-linking hydrazide. When mixed, the first and second aliquot portions of the reaction mixture react at a pH of 4 to 6 to form a solidified bioerodible composition within about 1 to about 10 minutes, to form a hydrazide cross-linked aldehydic polymer matrix. The bioerodable composition may be usefully employed to seal and/or treat wounds (e.g., a surgical incision).
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: March 4, 2014
    Assignee: Royer Biomedical, Inc.
    Inventor: Garfield P. Royer
  • Patent number: 8583260
    Abstract: The present invention is an electrophysiology, RF ablation, or similar catheter (i.e., catheter or sheath) that includes an actuator that significantly increases the length of travel (i.e., steering travel) of the actuation wires, as compared to the length of travel provided by prior art actuators. The catheter includes a hollow flexible tubular body, a pair of actuation wires disposed in a side-by-side relationship in the body, a handle attached to a proximal end of the body, an actuator pivotally mounted to the handle, an arcuate internal gear rack disposed on the actuator, one or more pulleys pivotally mounted on the handle and coaxially coupled to a pinion gear engaged with the gear rack, and a guide block mounted within the handle. The one or more pulleys include a first channel in which the first actuation wire resides and a second channel in which the second actuation wire resides. The actuation wires pass through holes in the guide block, which aligns the wires into their respective channels.
    Type: Grant
    Filed: December 28, 2004
    Date of Patent: November 12, 2013
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventor: John C. Knudson
  • Patent number: 8506530
    Abstract: An array for placement on the skin of a human or animal patient for the purpose of the transdermal application of pharmaceuticals, toxins or active agents, having microneedles that are situated on a carrier substrate, the microneedles having a preset breaking point in the area of the transition to the carrier substrate.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: August 13, 2013
    Assignee: Robert Bosch GmbH
    Inventors: Franz Laermer, Michael Stumber, Dick Scholten, Christian Maeurer
  • Patent number: 8480614
    Abstract: A contrast medium injection management apparatus includes a measuring unit which repeatedly measures the injection amount of contrast medium injected from at least one contrast medium injection device into a subject to be examined, a cumulative injection amount calculating unit which repeatedly calculates a cumulative injection amount at the start of examination or after an arbitrary point of time from the injection amount, and a display unit which displays the cumulative injection amount.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: July 9, 2013
    Assignees: Kabushiki Kaisha Toshiba, Toshiba Medical Systems Corporation
    Inventors: Satoru Ohishi, Takuya Sakaguchi
  • Patent number: 8273051
    Abstract: A pneumostoma management system includes a pneumostoma management device for maintaining the patency of a pneumostoma and a drug delivery device for pneumostoma care. The drug delivery device may be used to introduce therapeutic agents into the pneumostoma for direct treatment of the pneumostoma, treatment of the lung by way of collateral ventilation, and/or treatment of non-lung tissues by diffusion into the bloodstream. The drug delivery device includes a therapeutic agent dispenser for supplying a therapeutic agent and a propellant at positive pressure, an outlet and a connector for correctly positioning the outlet relative to a pneumostoma management device. The drug delivery device includes a self-centering and self-sealing connector for engaging the pneumostoma management device.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: September 25, 2012
    Assignee: Portaero, Inc.
    Inventors: Don Tanaka, Joshua P. Wiesman, David C. Plough
  • Patent number: 8029458
    Abstract: The invention relates to a device which is used to inject an implant (6) into tissues (50). The inventive device is characterized in that it comprises: a main hollow body (2; 2?) having a hollow needle (4; 4?) fixed thereto, into which the implant (6) is introduced; a secondary body (26; 26?) which is disposed coaxially inside the main body (2; 2?) and which surrounds the needle (4; 4?); and a plunger rod (36; 36?) which can slide coaxially inside the hollow needle (4; 4?).
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: October 4, 2011
    Assignee: Sociétéde Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.) SAS
    Inventors: Roland Cherif-Cheikh, Christophe Aubert, Thierry Rimlinger, Fabrice Bonacci, Serge Barneaud
  • Patent number: 8021320
    Abstract: A pneumostoma management system includes a pneumostoma management device for maintaining the patency of a pneumostoma and a drug delivery device for pneumostoma care. The drug delivery device may be used to introduce therapeutic agents into the pneumostoma for direct treatment of the pneumostoma, treatment of the lung by way of collateral ventilation, and/or treatment of non-lung tissues by diffusion into the bloodstream. The drug delivery device includes a therapeutic agent dispenser for supplying a therapeutic agent and a propellant at positive pressure, an outlet and a connector for correctly positioning the outlet relative to a pneumostoma management device. The drug delivery device includes a self-centering and self-sealing connector for engaging the pneumostoma management device.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: September 20, 2011
    Assignee: Portaero, Inc.
    Inventors: Don Tanaka, Joshua P. Wiesman, David C. Plough
  • Patent number: 7798976
    Abstract: An epicutaneous test plaster, which is intended for removable adhesion to a skin portion of a person subjected to testing, has a flexible carrier (10) with a medical adhesive layer (12) and a number of test chambers (31). The test chambers contain a filter element (17) for absorption of allergen and are oriented with their opening directed away from the flexible carrier (10). A removable cover layer (27, 32) extends over all the test chambers and the carrier (10) and is removably secured to them by means of the adhesive layer (12) of the carrier. According to the invention, the test chambers (31) are formed as separate chambers, which are each separately fixed to the carrier and which are made up of a number of different sub-layers (13, 17, 19, 20, 24, 26).
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: September 21, 2010
    Assignee: Chemotechnique MB Diagnostics AB
    Inventor: Bo Johan Niklas Niklasson
  • Publication number: 20090299274
    Abstract: An abrasion device and method for delivery of substances into the skin using a microabrader for delivering a substance into the skin are disclosed. An abrasion device with a cover is also disclosed. Such devices and methods can be effectively used to deliver bioactive substances into skin.
    Type: Application
    Filed: August 7, 2009
    Publication date: December 3, 2009
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventors: Phillipe Laurent, John A. Mikszta, Jason B. Alarcon
  • Publication number: 20090143724
    Abstract: Skin patches (20) having a microprojection array (10), a reservoir (18) containing an antigenic agent and an immune response augmenting adjuvant, and methods of using same to vaccinate animals (e.g., humans) is disclosed. In a preferred embodiment, the microprojection arrays (10) are composed of a photoetched and micro-punched titanium foil (14). The microprojections (12) are coated with a liquid formulation containing a vaccine antigen and an adjuvant such as glucosaminyl muramyl dipeptide, dried, and applied to skin of the animal to be vaccinated using an impact applicator. The microprojections (12) create superficial pathways through the stratum corneum to facilitate permeation of antigenic agent and adjuvant. Antigen dose and depth of penetration can be controlled. This technology has broad applicability for a wide variety of therapeutic vaccines to improve efficacy, and convenience of use.
    Type: Application
    Filed: February 6, 2009
    Publication date: June 4, 2009
    Applicant: Alza Corporation
    Inventors: Michel J.N. Cormier, James A. Matriano, Peter E. Daddona, Juanita A. Johnson, Wendy A. Young
  • Patent number: 7479124
    Abstract: A device for treatment of venous congestion provides for subcutaneous introduction of anticoagulant through an incision positioned within a collection shell for withdrawal of an effused material. A widened delivery tip provides dispersal of the anticoagulant and may be agitated to disrupt clot formation.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: January 20, 2009
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Gregory K. Hartig, Nadine P. Connor, Michael L. Conforti
  • Publication number: 20080214952
    Abstract: A replaceable cartridge for use in a minimally invasive allergy testing system includes a microneedle array; encapsulated allergens, and packaging to hold the array in alignment with the allergens. A method of manufacturing a replaceable cartridge is disclosed. A formable layer is placed on a mold having cavities and vacuum lines coupled to the cavities. Heat is applied to the formable layer and a negative pressure is applied to the vacuum lines to wrap the cavities with the formable layer. The wrapped cavities are filled with allergens. The filled cavities are covered with a plastic cover to form an encapsulated allergen assembly. A removable seal is applied over the plastic cover. A microneedle array having a substrate and at least one microneedle is formed. An energy storage device is coupled to the substrate to form a microneedle array assembly. The encapsulated allergen assembly is coupled with the microneedle array assembly.
    Type: Application
    Filed: July 11, 2006
    Publication date: September 4, 2008
    Inventors: Jose Mir, Dennis Roland Zander
  • Patent number: 7393114
    Abstract: An assembly according to the present invention includes a tattoo machine, a grip attached to the tattoo machine, and a light assembly inside the grip utilizing light emitting diodes (LEDs). The assembly further includes a power supply, a power cord for connecting the tattoo machine to the power supply, and two alligator clips conductively connected to the power cord or tattoo machine which transmit power to the light assembly via wires extending from the light assembly to the alligator clips.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: July 1, 2008
    Inventor: Joseph E. Devlin
  • Patent number: 7083592
    Abstract: An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. The dermal-access member extends at least 1 mm from the protrusion. A mechanism drives the device against the skin at a calculated speed of about 6 m/s to about 18 m/s.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: August 1, 2006
    Assignee: Becton Dickinson and Company
    Inventors: Alexander G. Lastovich, James K. Fentress, Julia Griggs, Ronald J. Pettis, Diane Sutter, Frank E. Martin, M. Ishaq Haider
  • Patent number: 7074210
    Abstract: Disclosed is a medical device used to prevent the cross-contamination of patients or injectors in which various components placed on the injector minimize or eliminate back splash contamination of the injector.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: July 11, 2006
    Assignee: Felton International, Inc.
    Inventors: Nathaniel J. Leon, Victor T. Rogatchev, Michael Mathews
  • Patent number: 6835184
    Abstract: A device includes a plurality of microneedles for abrading the stratum corneum of the skin to form a plurality of grooves in the tissue having a controlled depth and width. The microneedles have a length of about 5-250 microns and generally about 5-200 microns. The device is rubbed over the skin to prepare an abraded site after which a transdermal delivery or sampling device is applied to the abraded delivery site. The abrasion increases the permeability of the skin and the rate of delivery and extraction of a substance without pain or irritation to the patient.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: December 28, 2004
    Assignee: Becton, Dickinson and Company
    Inventors: Burton H. Sage, Carl Randolph Bock
  • Publication number: 20040236271
    Abstract: An agent delivery or sampling device (2) comprising a member (6) having a plurality of blades (4) for piercing the skin and a connecting medium (65) covering at least a part of the skin contacting side (48) of the member (6) for increasing transdermal flux of an agent.
    Type: Application
    Filed: June 29, 2004
    Publication date: November 25, 2004
    Inventors: Felix Theeuwes, Michel J.N. Cormier, Armand P. Neukermans
  • Patent number: 6808506
    Abstract: An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. The dermal-access member extends at least 1 mm from the protrusion. A mechanism drives the device against the skin at a calculated speed of about 6 m/s to about 18 m/s.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: October 26, 2004
    Assignee: Becton, Dickinson and Company
    Inventors: Alexander G. Lastovich, James K. Fentress, Julia Griggs, Ronald J. Pettis, Diane Sutter, Frank E. Martin, M. Ishaq Haider
  • Publication number: 20040186587
    Abstract: The present invention provides devices and methods for treating biological tissue. The treatment comprise implanting a scaffold implant device into in combination with a therapeutic material such as cells, tissue or cell components. The scaffold device serves to hold the therapeutic material at the treatment site, protecting it from being squeezed out by surrounding tissue. Additionally the scaffold device is believed to trigger an injury response that leads to angiogenesis in the tissue, which provides blood flow and nutrients to the associated therapeutic material to sustain it for a therapeutically effective amount of time. The devices may also be implanted at a tissue site already treated with a therapeutic material to initiate angiogenesis at the treatment site to sustain the material. The devices and methods also may be used to treat tumors with a necrosis factor.
    Type: Application
    Filed: January 28, 2004
    Publication date: September 23, 2004
    Applicant: C.R. Bard, Inc.
    Inventor: John E. Ahern
  • Publication number: 20040064087
    Abstract: An abrader device for delivering a substance into skin via an abrasion process includes a housing adapted to be pressed against the skin at a desired delivery site, an applicator head disposed in an upper opening of the housing and movable across a lower opening of the housing to abrade the delivery site in at least one furrow, and an abrader surface attached to the applicator head whereby the housing remains firm and stationary at the delivery site and structure of the housing and the applicator head controls parameters of the abrasion process. In particular, the amount of force or pressure applied to the abrader surface, the speed at which the abrader surface moves across the skin and the number of lateral passes of the abrader surface across the skin are controlled so that the abrader device provides a furrow with a length of substantially the same depth thereby providing reproducible results, even though different technicians are applying the abrader device against a patient's skin.
    Type: Application
    Filed: August 27, 2003
    Publication date: April 1, 2004
    Inventors: Alexander G. Lastovich, Frank E. Martin, M. Ishaq Haider, Richard P. Clarke, Jason B. Alarcon, John A. Mitszka, John P. Dekker, Weston Harding
  • Publication number: 20030220610
    Abstract: An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. The dermal-access member extends at least 1 mm from the protrusion. A mechanism drives the device against the skin at a calculated speed of about 6 m/s to about 18 m/s.
    Type: Application
    Filed: February 4, 2003
    Publication date: November 27, 2003
    Applicant: Becton Dickinson and Company
    Inventors: Alexander G. Lastovich, James K. Fentress, Julia Griggs, Ronald J. Pettis, Diane Sutter, Frank E. Martin, M. Ishaq Haider
  • Publication number: 20030199812
    Abstract: A transdermal delivery device includes a plurality of microneedles for injecting a substance such as a pharmaceutical agent into or below the stratum corneum of the skin. The device has housing formed from a top and bottom wall to define a chamber for containing a pharmaceutical agent. An inlet port is provided in the top wall of the housing for supplying the pharmaceutical agent to the chamber and directing the agent to the microneedles. The housing can have a Luer lock type fitting for coupling with a syringe having a Luer lock collar to inject the pharmaceutical agent into the housing. The housing can be divided into a plurality of chambers by an internal wall for supplying different agents simultaneously or sequentially to a patient. The microneedles have a length of about 5-250 microns and generally about 50-100 microns.
    Type: Application
    Filed: May 20, 2003
    Publication date: October 23, 2003
    Applicant: Becton, Dickinson and Company
    Inventor: Zeil B. Rosenberg
  • Publication number: 20030032919
    Abstract: A device for treatment of venous congestion provides for subcutaneous introduction of anticoagulant through an incision positioned within a collection shell for withdrawal of an effused material. A widened delivery tip provides dispersal of the anticoagulant and may be agitated to disrupt clot formation.
    Type: Application
    Filed: October 16, 2002
    Publication date: February 13, 2003
    Inventors: Gregory K. Hartig, Nadine P. Connor, Michael L. Conforti
  • Patent number: 6432100
    Abstract: An apparatus and method for generation of a protective sleeve against infections for a percutaneous lead through human or animal skin. The percutaneous lead (1) includes an extrusion port (7). When the lead extends through a body (3) of a patient, a pump (9) in operative connection with the lead is operative to move biocompatible liquid polymer material from a reservoir (10) through the extrusion port. As the polymer material comes in contact with body tissues of the patient it forms a protective sleeve against infections (5). The protective sleeve must be periodically clipped as it continuously or intermittently grows in an upward direction (6) outside of the body. The continual formation of the protective sleeve prevents the formation of a biofilm on the percutaneous lead that can cause the body tissue to separate from the percutaneous lead.
    Type: Grant
    Filed: November 10, 1999
    Date of Patent: August 13, 2002
    Inventor: Ing Klaus Affeld
  • Patent number: 6419661
    Abstract: Device for withdrawing Blood for Diagnostic Purposes. A lancet holder (8) for holding a lancet (7) and a lancet drive (12) having a loadable elastic drive spring (15) are provided within an elongated housing (2). The relaxing motion of the drive spring (15) is converted into a puncturing motion, after release of a locking device, to move the lancet (7), held by the lancet holder (8), at high speed in the puncturing direction until its tip exists out of an exit opening (5) of the housing (2). An improved handling and simultaneous minimization of pain is achieved by providing a two-sided rotary/translatory transmission (25) in the housing (2), wherein a) the input side (24) of the rotary/translatory transmission (25) transforms the motion of a loading button (17), protruding out of the rear end (16) of the housing.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: July 16, 2002
    Assignee: Roche Diagnostics GmbH
    Inventors: Hans Jürgen Kuhr, Richard Forster
  • Patent number: 6322808
    Abstract: A device (3) comprising a sheet member (6) having a plurality of microprotrusions (4) for penetrating the skin and a rigid support (15) contacting and extending across the sheet member (6) for transmitting an applied force evenly across the length and width of the sheet member (6) to reproducibly and reliably penetrate the skin with the microprotrusions (4).
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: November 27, 2001
    Assignee: ALZA Corporation
    Inventors: Joseph Creagan Trautman, Patrick S.-L. Wong, Peter E. Daddona, Hyunok Lynn Kim, Michael G. Zuck
  • Publication number: 20010031943
    Abstract: An apparatus for the treatment of tissue comprises a wound dressing (10) which has a porous layer (11) for contacting a wound site and a lumen tube (20) which includes at least first and second conduits (22,23). A proximal end (21) of the lumen tube is installed into the porous layer of the wound dressing and at least one distal end (40) of the tube provides a first coupling means (35) for coupling the first conduit to a source of vacuum supply and a second coupling means (43) which couples the second conduit to a source of treatment fluid which is beneficial to wound healing. The first and second conduits provide fluid communication between the porous layer (11) and the first and second coupling means.
    Type: Application
    Filed: February 28, 2001
    Publication date: October 18, 2001
    Inventor: Robert Graham Urie
  • Publication number: 20010009828
    Abstract: Essentially inelastic backing material for medical purposes, characterized in that the backing material has an addition of high-strength fibers, multi-strand yarns, mixed multistrands or filaments having an ultimate tensile stress strength of at least 60 cN/tex, preferably from 80 to 500 cN/tex, the high-strength fibers, multi-strand yarns, mixed multistrands or filaments having a water absorption of less than 10%, preferably less than 5% and, with particular preference, less than 3% and the high-strength fibers, multi-strand yarns, mixed multistrands or threads giving the backing material an ultimate stress strength of at least 50 N/cm, preferably from 60 to 450 N/cm and, with particular preference, from 65 to 250 N/cm, and in that the backing material is coated at least partially on at least one side with a hotmelt adhesive composition.
    Type: Application
    Filed: July 10, 1998
    Publication date: July 26, 2001
    Inventors: PETER HIMMELSBACH, STEFAN BODENSCHATZ
  • Patent number: 6258041
    Abstract: An allergen testing pick for receipt in the open top end of a vial of allergen and including a neck for close fit with the top end of such vial. The pick includes a stem depending downwardly from such neck and is formed with a plurality of sharp tines. A device may be provided for receiving the vials and may be in the form of a plurality of individual modules releasably coupled together.
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: July 10, 2001
    Inventor: Isadore Pitesky
  • Patent number: 6206270
    Abstract: A method of assembling needles for eyebrow makeup comprises the steps of inserting short needles into holes, wrapping a thermoplastic tube onto distal ends of short needles, inserting a long needle through thermoplastic tube and one hole such that sharp points of the needles contact top surface of planar heat-proof plate, moving needles and fastener plate assembly into oven to heat for integrally forming a needle assembly, taking needle assembly and fastener plate assembly from oven, removing needle assembly from the fastener plate assembly, inserting needle assembly into a hole through a tapered portion of fastener body for compressing the sharp ends of needles, and soldering needles together form a complete needle assembly.
    Type: Grant
    Filed: December 30, 1999
    Date of Patent: March 27, 2001
    Inventor: Te Shih Huang
  • Patent number: 6178348
    Abstract: A needle for use with an apparatus for injecting fluid into a pierced body orifice has a hollow body having an axis and an internal bore along the axis, a blunt, closed first end, an open second end with an interface to a closure for attachment to a reservoir, and one or more side openings at substantially a right angle to the axis communicating from the internal bore to outside the hollow body. The needle may be curved or straight. A fluid injection system based on the needle uses such as squeeze bottles or syringes to express material through the needle.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: January 23, 2001
    Inventors: Jeffrey Paul Denny, Mark A. Boys
  • Patent number: 6047209
    Abstract: A needle for use with an apparatus for injecting fluid into a pierced body orifice has a hollow body having an axis and an internal bore along the axis, a blunt, closed first end, an open second end with an interface to a closure for attachment to a reservoir, and one or more side openings at substantially a right angle to the axis communicating from the internal bore to outside the hollow body. The needle may be curved or straight. A fluid injection system based on the needle uses such as squeeze bottles or syringes to express material through the needle.
    Type: Grant
    Filed: April 2, 1999
    Date of Patent: April 4, 2000
    Inventors: Jeffrey Paul Denny, Mark A. Boys
  • Patent number: 5964729
    Abstract: A perforating device for dermal administration of medicine is disclosed. The device includes skin perforating members provided with a plurality of needles and received in a casing. The skin perforating members have alternately arranged needle discs and spacer discs which easily and evenly perforates the skin to a depth, suitable for dermal administration of medicine, by simply rolling the assembly on the skin. The device also includes a biasing mechanism for elastically vertically moving the assembly during skin perforating and thereby preventing the skin perforating members from excessively perforating the skin. The device informs the user of the excessive pressure of the assembly and thereby preventing possible skin damage.
    Type: Grant
    Filed: September 29, 1997
    Date of Patent: October 12, 1999
    Assignee: Samsung Electro-Mechanics Co., Ltd.
    Inventors: Sang Bae Choi, Kwang Kyun Jang
  • Patent number: 5713890
    Abstract: An apparatus and method are disclosed for marking the proper location of incisions to be made during a surgical procedure and for coloring the skin. The apparatus includes a pinwheel with a plurality of marking points extending therefrom for penetrating the outermost layer of the epidermis. A reservoir supplies a marking agent so that as the penetrating member penetrates the epidermis, marking agent is left within the epidermis, thereby leaving a dotted line which may be followed when making incisions during surgery. The method includes penetrating the outermost layer of the epidermis and leaving marking agent between the outermost layer of the epidermis and an innermost layer of the epidermis.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: February 3, 1998
    Assignee: University of Utah
    Inventor: Paul E. Chasan
  • Patent number: 5538134
    Abstract: A disposable allergen container apparatus for individual application to a patient of a plurality of allergens including a tray, a formed thermoplastic cover and an applicator. The tray includes a horizontal top web formed with a plurality of open top, vertically recessed wells arranged in predetermined spaced relationship and configured with respective bottom sinks configured to receive and store a supply of respective allergens therein. The cover includes a plate for overlying the web and is formed with a plurality of nesting rings arranged in the predetermined spaced relationship for centering over the respective sinks and spaced a predetermined distance therefrom.
    Type: Grant
    Filed: July 25, 1995
    Date of Patent: July 23, 1996
    Inventor: Isadore Pitesky
  • Patent number: 5496304
    Abstract: An apparatus and method are disclosed for marking the proper location of incisions to be made during a surgical procedure. The apparatus includes a member for penetrating inward of the outermost layer of the epidermis. A reservoir supplies a marking agent so that as the penetrating member penetrates the epidermis, marking agent is left inward of the outermost surface of the epidermis, thereby leaving a line which may be followed when making incisions during surgery. The method includes penetrating the outermost layer of the epidermis and leaving marking agent inward of the outermost layer of the epidermis. In a preferred embodiment of the method, a temporary marking agent, such as methylene blue, is used so that the line quickly disappears after surgery.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: March 5, 1996
    Assignee: University of Utah Research Foundation
    Inventor: Paul E. Chasan
  • Patent number: 5335670
    Abstract: An allergy testing method and apparatus for testing a patient for a plurality of allergies at substantially the same time, comprises a carrier for receiving a plurality of allergen applying devices, each allergen applying device including a source of an allergen and a movable pricking needle which is movable from an inactive position out of contact with the skin of a patient to an active position for pricking the skin of a patient and applying its associated allergen to the pricked skin when moved from the inactive position to the active position. The carrier holds and supports the plurality of allergen applying devices with a given spacing between each of the pricking needles, and an actuator is coupled to the carrier for moving the pricking needles from their inactive positions to their active positions to prick or pierce the skin of a patient and to thereby apply a respective allergen to the skin of the patient via the pricking needles.
    Type: Grant
    Filed: August 17, 1992
    Date of Patent: August 9, 1994
    Inventor: Henry Fishman
  • Patent number: 5320600
    Abstract: A device to effect simultaneous, en masse compressive-ejection of the content of plural, enveloped-ejectant containment-pods mounted therewithin the device.
    Type: Grant
    Filed: June 14, 1993
    Date of Patent: June 14, 1994
    Inventor: Wm. S. Lambert
  • Patent number: 5279552
    Abstract: An intradermal injection device is described which is placed against the skin of a patient and uses a reciprocating needle to inject ink, dye or similar fluid under the patient's skin, usually in a predetermined visible pattern. Unlike prior art devices of this type, however, the present device is readily disassembleable for rapid and thorough cleaning, since it is formed of a plurality of components which fit together through easily separable and cleanable couplings such as overlapping sealed (O-ring interference) fits or by threads. It also has a unique structure which avoids potential contamination of the drive components by having the drive mechanism offset at a substantial angle from the axis of the reciprocating needle and needle drive shaft and also by preferentially including internal fluid passage barriers such as fluid knock-out spaces. The device is preferably formed of metal such as aluminum or stainless steel, and may be electrically or fluid driven.
    Type: Grant
    Filed: January 11, 1993
    Date of Patent: January 18, 1994
    Inventor: Anton Magnet
  • Patent number: 5273528
    Abstract: A scarifier and dispensing device for inoculating livestock and other animals which includes an applicator at one end thereof and a scarifying tip extending from the opposite end thereof and which has an internal chamber for retention and dispensing of medicinal fluid which chamber is in communication with the applicator so that medicinal fluid may be dispensed as the applicator end is moved in contact with a prepared area of tissue.
    Type: Grant
    Filed: July 10, 1992
    Date of Patent: December 28, 1993
    Inventors: Mikell L. Skeen, Sam L. Shackelford
  • Patent number: 5242388
    Abstract: Apparatus for operating needle to inoculate the web of a bird's wing. An arm rocks a needle holder back and forth between a serum container and web positioner, along a path which causes the needle holder to move substantially vertically into and out of the container and web positioner. Gears cause the needle holder to pivot on the arm in response to pivotal movement of the arm, so that the needle points downwardly throughout its movement.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: September 7, 1993
    Assignee: Morf, Inc.
    Inventor: William M. Marshall, Sr.
  • Patent number: 5179959
    Abstract: An allergy testing system, for testing a patient for a plurality of allergies at substantially the same time, comprises a housing containing a plurality of packages or capsules containing an allergen and a needle, the needles being spaced apart from each other. The needles preferably carry the respective allergens on their tips. The housing is placed against the skin of a patient and an actuator is operated to engage the packages to move the needles to pierce or prick the skin of the patient, thereby applying the respective allergens to the pierced or pricked skin of the patient.
    Type: Grant
    Filed: October 29, 1991
    Date of Patent: January 19, 1993
    Assignee: Henry Fishman
    Inventors: Henry Fishman, Robert Olshaker, Gary Johnson