Arterial And Venous Needles Patents (Class 604/6.06)
  • Patent number: 9039646
    Abstract: A patient wearable, continuously operating extracorporeal pump apparatus which accesses the patient's arterial venous pressure differential by applying external pressure to a subcutaneous graft that has been cannualized to modulate blood flow through an extracorporeal circuit and to drive the pump for delivering a medicament, such as an anticoagulant, to the site of an intravenous cannula to prevent clogging thereof and also to move a dialysate through a circuit, including a dialyzer and a dialysate rejuvenating cartridge, whereby kidney failure can be treated without recourse to prior art hemodialysis machines found in most treatment facilities. With slight modification, the present invention can be used to remove excess fluids from CHF patients, to remove toxins from the blood in those suffering from liver failure and to facilitate administration of insulin to diabetics and/or glucose to those having hypoglycemia.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: May 26, 2015
    Inventor: Arnold J. Lande
  • Patent number: 8974394
    Abstract: A device and method for determining intravascular pressure and irregular needle placement in a hemodialysis procedure include analyzing means for automatically deriving venous access pressure (VAP) at a location of venous needle insertion into the patient and determining a ratio of VAP to mean arterial pressure, where the analyzing means determines multiple VAP values over multiple time periods and determines multiple ratios, one for each VAP value. Detecting means compare each ratio to a predetermined standard ratio derived from a moving average of prior VAP ratios, where the detecting means detects irregular needle placement when elevation of the ratio above the standard ratio is indicated.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: March 10, 2015
    Assignee: Henry Ford Health System
    Inventors: Stanley Frinak, Gerard Zasuwa, Jerry Yee, Anatole Besarab, John B. Kennedy, Douglas S. Curry, Helen Kimball Hirschman
  • Patent number: 8945036
    Abstract: The present invention includes a comprehensive replacement fluid system and method for the delivery of regional citrate anticoagulation (RCA) to extracorporeal blood circuits, wherein the system may include an online clearance monitor (OCM) and a circuit effluent online sensor system (OSS) for the continuous determination of patient plasma content of ultrafilterable solutes.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: February 3, 2015
    Assignee: Henry Ford Health System
    Inventors: Balazs Szamosfalvi, Stanley Frinak, Jerry Yee
  • Patent number: 8920355
    Abstract: An access disconnection method includes supporting a transmitter including a wireless communication apparatus, a receiver, a portion of an arterial line, a portion of a venous line and electronic circuitry by a member separate from a blood treatment machine. The method further includes operably communicating the electronic circuitry with the transmitter and the receiver, enabling transmission of a wave from the transmitter in one of the arterial and venous lines, enabling receipt of the wave by the receiver in the other of the arterial and venous lines, and enabling a disconnection output to be sent to the blood treatment machine via the electronic circuitry. The disconnection output is indicative of a change in the wave received by the receiver from the transmitter sufficient to expect that an access site disconnection of one of the arterial and venous lines has occurred.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: December 30, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Rodolfo Roger, Robert Childers, Thomas D. Kelly
  • Patent number: 8920356
    Abstract: A coupler includes a conductive polymer material that is so constructed and arranged to join tubing, wherein the conductive polymer material includes a conductive polymer component selected from the group consisting of polyaniline, polypyrrole, polythiophenes, polyethylenedioxythiophene, poly(p-phenylene vinylene) and mixtures thereof.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: December 30, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Sherwin Shang, Ramesh Wariar, Angel Lasso, George Lamberson, Dan F. Marcquenski, Jr., Jan Jensen, David Kuhn, Raf Castellanos
  • Patent number: 8915876
    Abstract: The present invention relates to a method for removing blood from an extracorporeal blood circuit and/or a functional device, each connectable or connected with a blood treatment apparatus for the purpose of blood treatment of a patient. The blood treatment apparatus of the method comprises or is connected with at least one extracorporeal blood circuit with a line having interior portions, the extracorporeal blood circuit comprising at least one arterial line section and at least one venous line section, wherein a first section of the arterial line section is configured to be connected with a second section of the venous line section, and further comprises at least one blood pump for conveying blood within the line interior portions. The method includes the step of operating the blood pump in a second conveying direction which is opposite to a first customary conveying direction. It further relates to corresponding apparatuses.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: December 23, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Soeren Gronau, Juergen Haecker, Ralf Mueller, Manfred Weis, Stefan Kreber, Martin Thys
  • Publication number: 20140330193
    Abstract: An access disconnection system includes: an arterial line; a venous line; a transmitter configured to transmit a sound wave in one of the arterial and venous lines when connected to a patient; a receiver configured to receive the sound wave from the other of the arterial and venous lines when connected to the patient; and electronic circuitry coupled to at least one of the transmitter and receiver, the circuitry configured to send a disconnection output indicative of a change in the sound waves received by the receiver from the transmitter sufficient to expect that an access disconnection of one of the arterial line and venous lines has occurred.
    Type: Application
    Filed: July 16, 2014
    Publication date: November 6, 2014
    Inventors: Rodolfo Roger, Robert Childers, Thomas D. Kelly
  • Patent number: 8852135
    Abstract: A method is provided for monitoring the introduction of substitution fluids for an extra-corporeal blood processing device with an extra-corporeal blood circuit, comprising an arterial blood line, running from an arterial patient connection to a first chamber of a dialyzer or filter divided into said first chamber and a second chamber by a membrane and a venous blood line, running from the first chamber of the dialyzer or filter to a venous patient connection. A device is provided for monitoring the introduction of substitution fluids for an extra-corporeal blood processing unit with an extra-corporeal blood circuit and an extra-corporeal blood processing device with a device for monitoring the introduction of substitution fluids. The method and the device for monitoring the introduction of substitution fluids are based on monitoring the fluid level in the bubble trap, arranged in the venous blood line of the extra-corporeal blood circuit.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: October 7, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Josef Beden, Itka Bado, Georg Verch
  • Patent number: 8834399
    Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the viability or one or more organs in a clinically dead organ donor or harvested donor organ for subsequent transplantation to an organ receiver patient.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: September 16, 2014
    Assignee: ZOLL LifeBridge GmbH
    Inventors: Gerhard Muller-Spanka, Hans-Reinhard Zerkowski
  • Patent number: 8834401
    Abstract: A process and apparatus are provided for managing and adjusting glucose levels in the blood of a patient during dialysis. The apparatus is a dialysis apparatus to treat patients with renal disease which includes a glucose scavenger to remove excess glucose from the blood before returning the blood to the patient and/or a device to increase blood glucose levels in the blood when the glucose level is below a threshold level. The glucose scavenger can include a glucose binding protein, boronic acid derivative, boronic ester derivative or mixture thereof bonded to the surface of a support such as a fiber bundle in a cartridge or the inner surface of tubing used in the apparatus.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: September 16, 2014
    Assignee: Becton, Dickinson and Company
    Inventors: James R. Petisce, Andrew Metters
  • Patent number: 8801646
    Abstract: An extracorporeal blood system includes: an extracorporeal blood machine; an arterial line extending from the extracorporeal blood machine; a venous line extending from the extracorporeal blood machine; and an access disconnection circuit for detecting a disconnection of at least one of the arterial or venous lines from a patient, the access disconnection circuit including (i) a signal generation source having first and second signal generation source electrical lines each in electrical communication with blood traveling through one of the arterial or venous lines, (ii) a conductive pathway electrically communicating blood traveling through the arterial line with blood traveling through the venous line, and (iii) a signal processing unit positioned and arranged to process a signal generated by the source to detect the disconnection of the at least one of the arterial and venous lines.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: August 12, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: James Han, Thomas P. Hartranft, Thomas D. Kelly, Angel Lasso
  • Patent number: 8784353
    Abstract: A device for reversing the blood flow for an extracorporeal blood treatment device, which has an extracorporeal blood circuit, includes an arterial blood line leading from a patient to a blood treatment unit and a venous blood line leading from the blood treatment unit to the patient. Furthermore, an extracorporeal blood treatment device includes a device for reversing the blood flow, and a method includes determining the reversal of the blood flow during an extracorporeal blood treatment. The device for reversing the blood flow for an extracorporeal blood treatment device includes two valve bodies which are rotated relative to one another for reversing the blood flow. The device for reversing the blood flow includes a communication device for receiving an electromagnetic high-frequency field from a read unit of the extracorporeal blood treatment device and for generating at least one identifier characterizing the position of the valve bodies which can be read by the read device.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: July 22, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Andreas Maierhofer, Malte Gross
  • Patent number: 8771215
    Abstract: A machine (1) for extracorporeal blood treatment comprises a device (2) for ultrafiltration of a liquid through a semi-permeable membrane (3) of a blood treatment device (4), a first sensor (11) for ultrafiltration rate through the membrane, a second group of sensors (13) for measuring a trans-membrane pressure, an infusion line (16) with an infusion pump (17) and a programmed controller (14) for calculating a maximum infusion rate as a function of the transmembrane pressure. The machine is suitable for kidney failure treatments, such as hemofiltration and hemodiafiltration. In a relatively short time the machine enables a large quantity of corporeal blood to be removed from the patient.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: July 8, 2014
    Assignee: Cambro Lundia AB
    Inventors: Claudio Tonelli, Bernd Wittner, Werner Beck, Helmut Hildwein, Reinhold Deppisch, Jonas Svensson, Bjorn Ericson
  • Patent number: 8721579
    Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to sustain patient life during a medical procedure such as cardiopulonary bypass graft surgery, keyhole cardiopulonary bypass graft surgery, percutaneous angioplasty, percutaneous stent placement, and percutaneous etherectomy.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: May 13, 2014
    Assignee: ZOLL LifeBridge GmbH
    Inventors: Gerhard Müller-Spanka, Hans-Reinhard Zerkowski
  • Patent number: 8684959
    Abstract: An extracorporeal blood treatment apparatus comprises a sensor (10) for emitting a signal indicating a change of hematic volume of an individual (7) subjected to a treatment and a weight loss system for actuating the individual's weight loss. A control unit (20) receives an effective weight value of the individual and a desired weight loss value and from these values determines a desired value of a change in hematic volume at end of treatment. The weight loss system is controlled on a basis of the hematic volume change signal and the desired value of the hematic volume change. The apparatus enables automatic control of a dialysis operation while preventing some complications arising from hypotension.
    Type: Grant
    Filed: July 3, 2009
    Date of Patent: April 1, 2014
    Assignee: Gambro Lundia AB
    Inventors: Francesco Paolini, Francesco Fontanazzi, Fabio Grandi
  • Patent number: 8591451
    Abstract: Methods, devices, and kits for creating bloodstream access in patients are provided. A patient's vessel is accessed surgically and blood flow is stopped. A short incision is made through the wall of one side of the vessel where the blood flow was stopped. A puncturing instrument is pushed through the incision across the lumen and through the vessel wall at a site opposite the incision. After the puncturing instrument is removed, a vessel wall traversing device which can be shaped like a blunt-ended nail with a hollow shank and a head of a larger diameter than the shank is inserted in the puncture hole blunt end first such that the shank traverses the puncture hole with the blunt end being positioned exterior to the outer surface of the vessel and the head of the device abutting inner surface of the vessel at the puncture hole.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: November 26, 2013
    Inventor: Marwan Tabbara
  • Patent number: 8562908
    Abstract: Systems and methods for providing for the automatic instrument-based rapid reprocessing of an intact extracorporeal circuit for use in hemodialysis. The system includes a manifold with connectors for engaging a dialyzer as well as venous and arterial blood lines. The manifold is adapted to be moved from a dialysis machine to a reuse instrument without removing the dialyzer and associated blood lines. The system allows for reprocessing of the extracorporeal circuit wherein prior to the next treatment, there is no residual chemical disinfectant requiring testing, the extracorporeal circuit is pre-primed, the levels in the bubble traps are set, and all of the required quality assurance tests are performed and recorded.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: October 22, 2013
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: Rodney S Kenley
  • Patent number: 8540657
    Abstract: Methods of and apparatuses for equine plasma collection are provided. Modified plasmapheresis instruments and modified disposable plasmapheresis tubing are introduced. By using the modified procedures and instruments, a high-speed, high volume, continuous-flow process of automated equine plasmapheresis is developed. The modified closed systems remove whole blood from the donor horses, separate plasma from the cellular components of blood, and simultaneously returning concentrated cells back to the donor horses.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: September 24, 2013
    Assignee: Auburn University
    Inventors: Kenny V. Brock, Sara Ziska
  • Patent number: 8454547
    Abstract: Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: June 4, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Patent number: 8430831
    Abstract: Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Extracorporeal devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: April 30, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Patent number: 8419672
    Abstract: A cannulation system for perfusing a patient's circulatory system, includes an inflow cannula having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump, an outflow cannula having a first end adapted to be connected to the blood pump and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: April 16, 2013
    Assignee: Droneon Pty Limited
    Inventor: Rodney James Lane
  • Patent number: 8343085
    Abstract: The present invention relates to a blood purification apparatus for extracorporeally circulating the blood of a patient so as to purify the blood for medical treatment incorporating a dialyzer and a method for priming the blood purification apparatus, wherein the present invention provides a blood purification apparatus and its priming method which can simply and easily automate the priming operation and also can surely and smoothly perform the bubble purging of the dialyzer.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: January 1, 2013
    Assignee: Nikkiso Co., Ltd.
    Inventors: Masahiro Toyoda, Satoshi Takeuchi
  • Patent number: 8328749
    Abstract: A blood purification apparatus includes a blood circuit having arterial and venous blood circuits, a blood pump, a blood purifying device, an indicator applying device that applies a predetermined indicator to the blood flowing extracorporeally through the blood circuit, a detecting device that detects the indicator applied by the indicator applying device, an arithmetic device that calculates, based on the indicator detected by the detecting device, a recirculation rate, and a calculating device that calculates an ideal extracorporeally circulating blood flow that results in the recirculation rate being no more than a predetermined value when the recirculation rate calculated by the arithmetic device is greater than the predetermined value. The recirculation rate is a proportion of a recirculated blood flow, which is reintroduced to the patient from the venous blood circuit and directed again to the arterial blood circuit, relative to an extracorporeally circulating blood flow.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: December 11, 2012
    Assignee: Nikkiso Co., Ltd.
    Inventors: Tomoya Murakami, Masahiro Toyoda, Yoshihiro Mori
  • Patent number: 8328750
    Abstract: A panel assembly for being manually mounted on a blood therapy apparatus is characterized by three panels, a center panel configured for manually securing a hemofilter cartridge and opposite side panels, hingedly connected to the center panel. The side panels have generally flat, planar interior surfaces defined by a rim extending around its perimeter. Tubing is secured along and adjacent to the interior panel surfaces, which are also provided with tubing supports having slanted tubing channels for supporting arched pump rotor engaging tubing sections and prevent tubing droop.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: December 11, 2012
    Assignee: B. Braun Avitum AG
    Inventors: Harold Peters, Adam Heintzelman, Jacob Kearns, Tommy Cooper
  • Patent number: 8211049
    Abstract: A blood processing system is disclosed which is adapted for single or double access draw and return. The blood processing system includes a blood processor for separating blood (or blood components) into one or more components or other components. In one embodiment the blood processor includes an inlet for receiving blood from blood source and an outlet for returning at least one blood component to the source. The processing system includes a first flow path in communication with the inlet, a second flow path in communication with the outlet, a third flow path in communication with a second flow path at two spaced apart locations, a reservoir communicates with the third flow path between the two spaced apart locations, and a flow communication site associated with the second flow path downstream of the spaced apart locations which communication site is adapted to permit communication with the first flow path.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: July 3, 2012
    Assignee: Fenwal, Inc.
    Inventor: Kyungyoon Min
  • Patent number: 8197431
    Abstract: An acoustic access disconnect detection system is useful for detecting when an access needle has become dislodged or when blood is leaking. The acoustic disconnect detection system includes an acoustic transmitter and one or more acoustic sensors placed upstream of an access site of a patient, the sensors suitable for generating and detecting an acoustic signal that is intended to pass unobstructed through the access site. The acoustic transmitter may be placed on a therapy machine for generating an acoustic signal. The acoustic sensor is mounted downstream of the transmitter, such as on the therapy machine where blood is pumped to or returned from the patient, on the patient, or on the therapy machine where blood is entering the therapy machine. The therapy machine, such as a dialysis machine, may be programmed not to start or continue operation unless the acoustic signal is within certain parameters.
    Type: Grant
    Filed: September 21, 2007
    Date of Patent: June 12, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: Corrie Bennison
  • Patent number: 8109893
    Abstract: A patient wearable, continuously operating extracorporeal pump apparatus which accesses the patient's arterial venous pressure differential by applying external pressure to a subcutaneous graft that has been cannualized to modulate blood flow through an extracorporeal circuit and to drive the pump for delivering a medicament, such as an anticoagulant, to the site of an intravenous cannula to prevent clogging thereof and also to move a dialysate through a circuit, including a dialyzer and a dialysate rejuvenating cartridge, whereby kidney failure can be treated without recourse to prior art hemodialysis machines found in most treatment facilities. With slight modification, the present invention can be used to remove excess fluids from CHF patients, to remove toxins from the blood in those suffering from liver failure and to facilitate administration of insulin to diabetics and/or glucose to those having hypoglycemia.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: February 7, 2012
    Inventor: Arnold J. Lande
  • Patent number: 8021319
    Abstract: A blood set comprises an arterial line having a patient end provided with a multiport connector (14) having first port (15) connected to a blood transport tube (13), a second port (16) bearing a male luer connector for connecting to a vascular access device (17), and a third port (18) connected to a service tube (20) terminating with female luer connector (23) for connection with a priming liquid supply line. The blood set operates rapidly and with a small risk of contamination for the patient.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: September 20, 2011
    Assignee: Gambro Lundia AB
    Inventors: Annalisa Delnevo, Roberto Neri
  • Patent number: 7867214
    Abstract: In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: January 11, 2011
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Robert W. Childers, David S. Brown, Ramesh Wariar, Sujatha Karoor, Shahid Din, Leo Martis, Cody Buchmann, Paul Soltys
  • Patent number: 7850634
    Abstract: An improved method for separating whole blood into components and collecting a desired blood component. The method allows a desired blood component to be subjected to centrifugal forces within a separator for prolonged periods of time, yielding a cleaner cut and higher yield of the desired blood component. Whole blood is drawn from a source and pumped into a separator, the undesired blood components are removed from the separator at rates so as to build up the desired blood component in the separator. The desired blood component is only removed after a predetermined amount of the desired blood component has built up in the separator. It is preferred that the desired blood component be buffy coat and that the method be used to perform photopheresis treatments. In another aspect, the invention is a method of performing a full photopheresis treatment to treat diseases in a reduced time, preferably less than about 70 minutes, and more preferably less than about 45 minutes.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 14, 2010
    Assignee: Therakos, Inc.
    Inventor: Dennis Briggs
  • Patent number: 7824356
    Abstract: A system is disclosed for removing gas bubbles from blood during circulatory assist procedures. Such bubbles are generated, along with particulate matter, in an extracorporeal circulatory bypass system by the pump, oxygenator and other components. Filters are used in the line to remove particulates and bubbles from the blood before they are pumped back to the patient but current filters are inefficient at removing small bubbles and debris that can cause neurological defects and renal and other organ failures in the patient. An active filter apparatus and method is disclosed that forces the bubbles to the center of the system where they are removed from the blood before the blood exits the filter. The filter comprises an axially elongate cylindrical shell with a blood inlet, a blood outlet and a gas outlet.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: November 2, 2010
    Assignee: Indian Wells Medical, Inc.
    Inventors: David W. Wieting, Jay A. Lenker
  • Patent number: 7794419
    Abstract: The apparatus for blood flow control in an extracorporeal circuit comprises: a user interface for setting a desired blood flow value (qbREAL) and a datum relating to the vascular access, a memory for recording a plurality of mathematical relations having mathematical expressions relating to the vascular access organ to be used, and a control unit. The control unit identifies the vascular access, selects, from among the plurality of mathematical relations present in the memory, a relation which corresponds to the vascular access identified, and calculates, as a mathematical function of the set value for the desired flow (qbREAL), a value at which to set the angular velocity of the pump associated to the extracorporeal circuit and/or a theoretical value of the arterial pressure upstream of the pump.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: September 14, 2010
    Assignee: Gambro Lundia AB
    Inventors: Francesco Paolini, Carlo Alberto Lodi, Francesco Fontanazzi
  • Patent number: 7766853
    Abstract: A cannulation system (10) for perfusing a patient's circulatory system, includes an inflow cannula (14) having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump (19), an outflow cannula (23) having a first end adapted to be connected to the blood pump (19) and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump (19) is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: August 3, 2010
    Assignee: Droneon Pty Limited
    Inventor: Rodney James Lane
  • Patent number: 7758532
    Abstract: A blood purification device that does not require measurement of a patient's blood concentration performed ahead of time and that allows treatment time to be reduced, thus reducing the burden on the patient, and allows monitoring of problems in the internal elements. The present invention includes: blood purification device main units including a blood pump disposed in an arterial blood circuit, a blood purification device purifying blood, and an ultrafiltration pump for draining water from blood; first measuring means and second measuring means measuring hematocrit values and disposed at the arterial blood circuit and the venous blood circuit respectively; calculating means calculating a ratio for measured hematocrit values and a ratio for a theoretical hematocrit values determined from a predetermined equation and evaluating means evaluating whether the values determined by calculating means are roughly similar.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: July 20, 2010
    Assignee: Nikkiso Co., Ltd.
    Inventors: Yoshihiro Mori, Takayuki Ohishi
  • Patent number: 7708710
    Abstract: Methods are disclosed for collecting and separating whole blood into one or more components. A disposable blood separation fluid circuit is provided which is adapted to cooperate with a reusable separation controller. The fluid circuit includes a fluid flow path for communication with a blood source and at least one container in fluid communication with the fluid flow path. The fluid flow path is connected to a blood source and quantities of whole blood are collected in the container and one other location within the fluid circuit. The source is then disconnected from the disposable fluid circuit. The quantities of whole blood are centrifugally processed, with processing of at least a portion of one of the quantities beginning after the source is disconnected from the fluid circuit.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: May 4, 2010
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, Richard I. Brown
  • Patent number: 7704213
    Abstract: A measurement method for determining the blood flow rate QF in blood carrying lines is provided. It may be used in particular to determine the blood flow in a patient's vessel, which is connected to the extracorporeal circulation of a blood treatment machine by an arterial line and a venous line. According to the method, the net rate dX/dt of a variable X is determined, with X being derived from a physicochemical variable Y of the blood with the help of values YA and YV which are adequately constant over time and which respectively characterize the physicochemical property in the arterial line and the venous line during the measurement interval. The net rate dX/dt is then used to determine the blood flow rate QF. The targeted use of indicators is not necessary.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: April 27, 2010
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Matthias Kraemer
  • Patent number: 7686777
    Abstract: An in-vitro blood plasma lipids filtering method includes the following steps: separating out the blood plasma from the blood collection; flushing a filtering device with saline solution; controlling the pressure of the separated blood plasma; passing the blood plasma to the filtering device for filtering out lipids; controlling the temperature of the filtered blood plasma; and feeding the blood plasma back to the blood. The method is clearly effective and accurate, quick response indication, securer and safer, more tolerant, and the treatment time is short.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: March 30, 2010
    Assignee: Shanghai Jiangxia Blood Technology Co., Ltd.
    Inventors: Heping Huang, Siukwan Chang
  • Patent number: 7682327
    Abstract: The present invention provides a heart-lung machine which can be carried by one person and can be used independently from an external power supply, consisting of at least three modules (1, 2, 3), wherein a first module (1) contains the blood circulating elements which are necessary for the function of a heart-lung machine, a second module (2) contains a pump drive (9) and an electronic measuring equipment and a control logic (11) and a third module (3) contains the programming unit (14), whereas the second unit is separably connected to the first and the third module.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: March 23, 2010
    Assignee: Lifebridge Medizintechnik AG
    Inventor: Karsten Kirchhof
  • Patent number: 7674236
    Abstract: A device and method for detecting complications during an extracorporeal blood treatment are provided. During the dialysis treatment, the dialysance or clearance may be continuously determined at successive points in time based on a measured change in a physical or chemical characteristic quantity of the dialysis liquid, for example, the ion concentration of the dialysis liquid. In the event a significant change in the dialysance or clearance is established, the determination of the recirculation may be effected based on a measured change in a physical or chemical characteristic quantity of the blood. When both a significant change in the determined dialysance as well as in the recirculation occurs, a complication may be assumed with regard to a bad vessel access. Alternatively, a complication may be assumed with regard to the dialyzer.
    Type: Grant
    Filed: October 15, 2005
    Date of Patent: March 9, 2010
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Pia Daniel, Carsten Müller
  • Patent number: 7615028
    Abstract: An extracorporeal blood treatment system including: a blood circuit having a first blood passage coupled at a first end to a first end of a blood treatment device and a second blood passage coupled at a first end to a second end of the treatment device, wherein the first and second blood passages each have a second end adapted to be coupled to a vascular system of a human patient; a first blood pump connectable to the first blood passage and a second blood pump connectable to the second blood passage, wherein said first and second blood pumps are adapted to move blood through the first and second blood passages in a first direction and in a reverse direction, and a pump controller operatively connected to the first and second blood pumps, said controller operates the blood pumps to cyclically move blood through the first and second blood passages in the first direction and the reverse direction.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: November 10, 2009
    Assignee: CHF Solutions Inc.
    Inventor: John J. O'Mahony
  • Patent number: 7530962
    Abstract: The present invention describes a system, apparatus, and method for detection of disconnection of a device from a patient, such as dislodgment of a device during medical treatments or therapies, using a patient's electrical voltages.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: May 12, 2009
    Inventors: Edward Allan Ross, Rosalind J. Sadleir
  • Patent number: 7351218
    Abstract: A device for treating blood by extracorporeal circulation comprising a filter having a first chamber and a second chamber separated by a semi-permeable membrane. The device has an arterial line connected to the first chamber of the filter, a venous line issuing from the first chamber of the filter, a channel used for pre-infusion of a substance for regional anticoagulation and linked to the arterial line, a purge channel issuing from the second chamber of the filter, and an air separator on the venous line. The device also includes a line for post-infusion of a solution at least partially re-establishing the ionic equilibrium of the blood downstream of the air separator, the post-infusion line being configured immediately upstream of an air detector.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: April 1, 2008
    Assignee: Gambro Lundia AB
    Inventor: Bernard Bene
  • Patent number: 7172569
    Abstract: A method and a device for determining the blood flow QF in a vascular access (F) during an extracorporeal blood treatment is described, where the blood enters the blood treatment unit (3) of the blood treatment machine through an arterial branch (19) of an extracorporeal circulation loop (2) which is in fluid connection with the vascular access at an arterial connection. The blood is returned through a venous branch (21) of the extracorporeal circulation, which is in fluid connection with the vascular access at a venous connection (13). The blood flow in the vascular access is determined by measuring the pressure part, pven, in the arterial and/or venous branch of the extracorporeal circulation when the vascular access is open and interrupted, while the extracorporeal blood flow QB is varied. Then the fistula flow QF is determined from the measured values for the arterial and/or venous pressure while the vascular access is open and interrupted.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: February 6, 2007
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Wolfgang Kleinekofort
  • Patent number: 7138088
    Abstract: Apparatuses, devices, systems and methods for detecting access disconnection are provided. The present invention includes electrical contacts in fluid and electrical communication with a fluid passing between a patient and a medical system during therapy. In this regard, the present invention can use a direct-contact measurement to detect access disconnection, such as dislodgment of an access device from the patient through which fluid can flow during therapy including, for example, medication delivery, dialysis therapy and the like.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: November 21, 2006
    Assignee: Baxter International Inc.
    Inventors: Ramesh Wariar, James Han, George Lamberson, Thomas P. Hartranft, Thore Falkvall
  • Patent number: 7037428
    Abstract: A system for automatically processing blood components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control circuitry, and a unique disposable set that includes a cassette supporting a centrifuge with an improved design, pump interfaces with an improved design, component and solution bags, and tubing. Various processes are implemented using a specific disposable set for each process which allows automatic identification of the process to be performed the console.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: May 2, 2006
    Assignee: Mission Medical, Inc.
    Inventors: Thomas C. Robinson, Thomas P. Robinson, Richard D'Elia, Paul Eibe, Thomas Sahines
  • Patent number: 6913588
    Abstract: A circuit for extracorporeal treatment of a body fluid, the circuit including in serial fluidic communication an inlet for receiving the body fluid from a patient, a first pump, a first treatment device for processing the body fluid, a second pump, an outlet for returning processed body fluid to the patient; and a shunt. The shunt is upstream from the first pump and downstream from the second pump.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: July 5, 2005
    Assignees: Nephros Therapeutics, Inc., The Regents of the University of Michigan
    Inventors: William Frederick Weitzel, H. David Humes, Emil Presley Paganini, Deborah Ann Buffington, Angela J. Funke
  • Patent number: 6890315
    Abstract: A method and apparatus for ultrafiltration of blood operating by removing blood from a peripheral blood vessel at a rate of less than two percent of total cardiac output of a patient, extracting fluid at a rate of 0.1 liter to 1.0 liters per hour while retaining cells and proteins in the blood, and returning the concentrated blood to a secondary blood vessel is disclosed. Blood is removed and returned using small gage needles. As a pump circulates blood from the patient, a filter removes ultrafiltrate from the blood using duty cycle or pump control, and a transparent container collects the removed fluid.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: May 10, 2005
    Assignee: CHF Solutions, Inc.
    Inventors: Howard R. Levin, Mark Gelfand, John O'Mahony, Hans-Dietrich Polaschegg
  • Patent number: 6827698
    Abstract: A method and a device for determining the blood flow QF in a vascular access (F) during an extracorporeal blood treatment is described, where the blood enters the blood treatment unit (3) of the blood treatment machine through an arterial branch (19) of an extracorporeal circulation loop (2) which is in fluid connection with the vascular access at an arterial connection. The blood is returned through a venous branch (21) of the extracorporeal circulation, which is in fluid connection with the vascular access at a venous connection (13). The blood flow in the vascular access is determined by measuring the pressure Part, Pven, in the arterial and/or venous branch of the extracorporeal circulation when the vascular access is open and interrupted, while the extracorporeal blood flow QB is varied. Then the fistula flow QF is determined from the measured values for the arterial and/or venous pressure while the vascular access is open and interrupted.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: December 7, 2004
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Wolfgang Kleinekofort
  • Patent number: 6796955
    Abstract: A method and apparatus are disclosed for controlling blood flow through an extracorporeal blood circuit having a controller comprising the steps of: withdrawing the blood from a withdrawal blood vessel in a patient into the extracorporeal circuit, treating the blood in the circuit and infusing the treated blood into the patient; detecting an occlusion which at least partially blocks the withdrawal or infusion of the blood; reducing the blood flow rate and the rate of filtration in response to the occlusion, and further prompting the patient to move his arm in an effort to alleviate the occlusion.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: September 28, 2004
    Assignee: CHF Solutions, Inc.
    Inventors: John J. O'Mahony, Andrew Halpert, Edward G. Rychlick, Mark Gelfand
  • Patent number: 6663585
    Abstract: A method and device for monitoring vascular access is described. A field coil is placed at a location on an extracorporeal circulation loop connected to the vascular system of a patient, and an induction coil is placed at another different location. A voltage is supplied to the field coil, inducing an electric current in the blood. The current induces a voltage in the induction coil. Monitoring the voltage in the induction coil reveals if vascular access is defective.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: December 16, 2003
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Helmuth Ender