Filter Means Patents (Class 604/6.09)
  • Patent number: 10940252
    Abstract: A blood purification apparatus with an arterial puncture needle or a venous puncture needle is stuck in the patient can be easily notified at the activation of a blood pump in an unconnected step. A blood purification apparatus includes a blood circuit for circulating blood, a dialyzer capable of purifying the blood, a blood pump provided to an arterial blood circuit for delivering a liquid, and a control device that executes a connected step in which the blood pump is activated when an arterial puncture needle (a) and a venous puncture needle (b) are in the patient and an unconnected step in which the blood pump is activated with neither the arterial puncture needle (a) nor the venous puncture needle (b) being stuck in the patient. The control device establishes, in the unconnected step, a restricted state where the behavior of the blood pump at the activation of the blood pump is restricted.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: March 9, 2021
    Assignee: Nikkiso Company Limited
    Inventors: Masahiro Toyoda, Akira Sugioka
  • Patent number: 10881765
    Abstract: A blood component collection cassette, kit, or system, and a flow path internal pressure detection method capable of accurately measuring a circuit internal pressure. A flow path formed in a cassette body has a first line through which blood flows when a blood component separation device is in operation, and a second line through which blood does not flow when the blood component separation device is in operation. The first line has a first pressure-receiving portion pressed by a first load detector. The second line has a second pressure-receiving portion pressed by a second load detector.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: January 5, 2021
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Masatsugu Igarashi
  • Patent number: 10828635
    Abstract: An apparatus for isolating bubbles from a liquid comprises at least a main body; an inlet tube and an outlet tube disposed at a side of the main body which includes an accommodation chamber and a column disposed atop, the inlet tube is formed with an aperture within the accommodation chamber, and the outlet tube is disposed at a position below the inlet tube; and a coupling tube disposed within the accommodation chamber, and includes a first end connected to the inlet tube and a second end corresponding to and separating from the outlet tube by a gap. During use, a liquid dispersed with bubbles is introduced through the inlet tube. The bubbles pass through the aperture along with a small portion of the liquid and ascend toward a top of the accommodation chamber and are then collected by the column.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: November 10, 2020
    Assignee: Tantti Laboratory Inc.
    Inventors: Pang Lin, Hui Chen
  • Patent number: 10799628
    Abstract: A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: October 13, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Michael J. Wilt, Kevin L. Grant, James D. Dale, Jason A. Demers, Brian D. Tracey
  • Patent number: 10787376
    Abstract: Device for water disinfection by ultrafiltration. The device comprises a filtering assembly with at least one ultrafiltration membrane (6) inside a casing (10); a pump (5, 15), powered with electrical energy, configured for driving water to be filtered to said at least one ultrafiltration membrane (6); and an electric supply connection (2) for powering said pump (5) from a power supply. Said at least one ultrafiltration membrane is located in said casing (10) in a position in which it receives the feed flow of the water to be filtered by gravity or pressure; the electric power supply is provided by a battery included in a portable communication device (4); and the intensity of the current consumed by the pump (5, 15) is below 1.2 A, with a supply voltage of up to 24 V.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: September 29, 2020
    Inventor: Antonio Cuevas Cuadrado
  • Patent number: 10780212
    Abstract: A blood component collection system (10) includes a first internal pressure calculation unit (110) adapted to calculate a first internal pressure of a first pressed portion (60) using first calibration curve data (118), a second internal pressure calculation unit (112) adapted to calculate a second internal pressure of a second pressed portion (62) using second calibration curve data (120), and a correction unit (114) adapted to correct the first calibration curve data (118) in a manner so that the first internal pressure becomes equal to the second internal pressure in a state in which operation of a collection and returning pump (100) is stopped during at least one of a collection operation and a returning operation of a first cycle.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: September 22, 2020
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Masatsugu Igarashi
  • Patent number: 10758665
    Abstract: A biological component collection system and a circuit internal pressure acquisition method are provided, which are capable of accurately measuring the circuit internal pressure. A centrifugal separation device of a blood component collection system comprises an estimated data calculation unit that calculates estimated data B on the basis of initial data A, and a correction unit that corrects the estimated data B in a manner so that the internal pressure calculated by a first internal pressure calculation unit becomes equivalent to the internal pressure calculated by a second internal pressure calculation unit.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: September 1, 2020
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Masatsugu Igarashi, David Benz
  • Patent number: 10758664
    Abstract: A centrifugal separation device of a blood component collection system comprises a data acquisition unit that acquires initial data A, an estimated data calculation unit that calculates estimated data B on the basis of the initial data A, a reaction force calculation unit which calculates a reaction force of a first applied load measurement unit on the basis of the estimated data B, and an internal pressure calculation unit that calculates an internal pressure of the first applied load measurement unit, based on the reaction force and a load detected by a first load detecting unit.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: September 1, 2020
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Masatsugu Igarashi
  • Patent number: 10744251
    Abstract: A dialyzer composed of: first and second dialyzation chambers, and an intermediate chamber interposed between the first and second dialyzation chambers. Each of the chambers has a respective one of a blood inlet or outlet and a dialysate inlet or outlet arranged so that blood and dialysate flow in counter-current to one another in both chambers. The intermediate chamber is connected to form a dialysate-free blood flow passage between the blood chambers and is configured to maintain a substantially uniform blood flow.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: August 18, 2020
    Assignee: MIRIMEDICAL LLC
    Inventors: Gary Mishkin, Mark Scott Goodin
  • Patent number: 10737009
    Abstract: The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfills at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage device, a computer program product, and a computer program.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: August 11, 2020
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Paul Chamney, Ulrich Moissl, Peter Wabel, Volker Nier, Sebastian Wieskotten
  • Patent number: 10602212
    Abstract: Methods and systems for routing key commands received from a remote-control device are provided. The method and/or system may include receiving, at a device, a key command from the remote-control device, generating a first message that includes the key command, sending, from the device, the first message to a keystroke router, and determining, at the keystroke router, a system network controller associated with the device. Moreover, the keystroke router may send the key command to the system network controller.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: March 24, 2020
    Assignee: SONIFI SOLUTIONS, INC.
    Inventors: Derin Michael Zerr, Joel Walter Zdepski, Christopher Paul Wollmann, Shaun Eugene Marko, Daniel A. Dirks, Joshua H. Pulford
  • Patent number: 10589015
    Abstract: An artificial lung including a housing having a circular outer wall being enclosed by a first surface and a second surface to define an interior volume, a blood inlet port to permit inlet flow of blood to the housing, a blood outlet port to permit outlet flow of the blood from the housing, a gas inlet port to permit inlet flow of a gas to the housing, a gas outlet port to permit outlet flow of the gas from the housing, and a plurality of baffles concentrically disposed within the housing. The baffles are positioned to define a flow path between the blood inlet port and the blood outlet port. Each of the baffles includes a gate opening to permit flow of the blood along the flow path. A fiber bundle is disposed between the baffles within the flow create mixing and improve gas exchange efficiency.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: March 17, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Robert H. Bartlett, Joseph L. Bull, Uditha Piyumindri Fernando
  • Patent number: 10493196
    Abstract: A method of draining a device for extracorporeal blood treatment, wherein the device comprises a dialyzer which is divided by means of a membrane into a first chamber and a second chamber, an arterial line connected to a blood inlet of the first chamber, a venous line connected to a blood outlet of the first chamber, a dialysis fluid line for fresh dialysis fluid connected to a dialysis fluid inlet of the second chamber and a dialysis fluid line for used dialysis fluid connected to a dialysis fluid outlet of the second chamber, a blood pump disposed in the arterial line, a venous expansion chamber disposed in the venous line and an air detector unit downstream of the venous expansion chamber, and wherein the method comprises the following steps of: connecting a patient-side port of the arterial line to a patient-side port of the venous line; generating a negative pressure in the second chamber; operating the blood pump in a first direction and draining the arterial and venous lines in the first direction via
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: December 3, 2019
    Assignee: B. Braun Avitum AG
    Inventor: Heiko Riemenschneider
  • Patent number: 10471200
    Abstract: A blood purification apparatus capable of achieving a simplified configuration and switching between hemodialysis treatment (HD), hemofiltration treatment (HF), and hemodiafiltration treatment (HDF) as well as selecting from pre-dilution, post-dilution and pre and post-dilution easily and smoothly.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: November 12, 2019
    Assignee: Nikkiso Company Limited
    Inventor: Hiroaki Mochizuki
  • Patent number: 10342912
    Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: July 9, 2019
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T. K. Ling, Ying-Cheng Lo
  • Patent number: 10335534
    Abstract: Systems and methods are provided for determining an estimated risk of arrhythmia during or after dialysis based on changes in serum potassium concentration of a patient and an amount of fluid removed from the patient during dialysis. The systems and methods allow for a determination of a risk that arrhythmia will occur due to the changes in potassium and fluid volume of a patient during dialysis, and for optimizing a dialysis prescription in order to minimize the risk of arrhythmia.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: July 2, 2019
    Assignee: Medtronic, Inc.
    Inventors: Amy Roettger, VenKatesh R. Manda, John Burnes, Rebecca Poindexter, Martin T. Gerber
  • Patent number: 10258729
    Abstract: A method for pumping and oxygenating blood includes receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet. The flow of gas is passed through the hollow fibers from the gas inlet manifold to a gas outlet manifold. The flow of gas is output from the gas outlet manifold via a gas outlet. An impeller is rotated to generate a flow of blood that flows over the hollow fibers. Oxygen from the flow of gas is transferred to the flow of blood through the hollow fibers. Carbon dioxide is transferred from the flow of blood to the flow of gas through the hollow fibers.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: April 16, 2019
    Assignees: Thoratec LLC, University of Maryland, Baltimore
    Inventors: Barry N. Gellman, Andrew Koert, Zhongjun Wu, Juntao Zhang, Bartley P. Griffith
  • Patent number: 10195336
    Abstract: There are provided a blood purification apparatus and a priming method thereof which can reliably perform air bubble purging of a blood purification device while workability is maintained during priming. During the priming, an air purging step is performed by causing a blood pump to perform reverse rotation, and electromagnetic valves and are brought into an opened state so as to open the overflow line (L) and a priming solution supply line and so as to discharge a priming solution from an overflow line while supplying a dialysate functioning as the priming solution from the priming solution supply line.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: February 5, 2019
    Assignee: NIKKISO COMPANY LIMITED
    Inventors: Kentaro Kogoshi, Satoshi Takeuchi
  • Patent number: 10130744
    Abstract: An apparatus for extracorporeal blood treatment comprises a sensor (10) for emitting a signal indicating a variation in blood volume (?Bv?) of an individual (7) subjected to extracorporeal blood treatment and a sensor (14) for emitting a signal indicating a weight loss of the individual. A control unit (20) receives the signals, compares the ratio between the relative variation of blood volume (?Bv/BV) and the relative variation of weight loss (AWL/TW) of the individual with a desired value, and controls the weight loss of the individual on the basis of the comparison. The apparatus enables automatically controlling a dialysis, preventing some complications due to hypotension.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: November 20, 2018
    Assignee: Gambro Lundia AB
    Inventors: Francesco Fontanazzi, Francesco Paolini, Fabio Grandi
  • Patent number: 10111999
    Abstract: Devices and methods for enhancing the operations of fluid systems are provided. For example, this document provides variable-elevation drop tubes that are well suited for use with medical fluid reservoirs. While the variable-elevation drop tubes provided herein are described in the context of a medical fluid system, such as an extracorporeal blood flow circuit, it should be understood that the devices and methods provided herein are not limited to such contexts.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: October 30, 2018
    Assignee: Terumo Cardiovascular Systems Corporation
    Inventors: Gregory Peter Muennich, Michael Washko, Timothy John Canatella
  • Patent number: 9931456
    Abstract: An extracorporeal treatment assembly including a pump and a controller wherein an extracorporeal circuit is mounted to the assembly, the controller causes the assembly to: control the pump to pump liquid through the passage and the flow coupling; collect actual fluid pressure data; store circuit type data uniquely corresponding to a certain type of extracorporeal circuit; determine a dimension of the certain type of extracorporeal circuit; determine an expected fluid pressure for the certain type of extracorporeal circuit; based on a comparison of the actual fluid pressure data and the expected fluid pressure, determine whether the certain type of extracorporeal circuit corresponds to the actual extracorporeal circuit.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: April 3, 2018
    Assignee: Gambro Lundia AB
    Inventors: Paolo Rovatti, Fabio Roncadi, Bruno Genovese, Pier Giorgio Verdi
  • Patent number: 9907894
    Abstract: A hemodialysis apparatus 1 is provided with a dialyzer 2 for performing hemodialysis, a blood circuit 3 connected to the dialyzer, a dialysis solution circuit 4 connected to the dialyzer, a replacement fluid port 31 provided in the dialysis solution circuit and capable of being opened and closed by a lid member, and a replacement fluid passage 6 having its one end connected to the blood circuit and the other end connected to the replacement fluid port.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: March 6, 2018
    Assignee: SHIBUYA KOGYO CO., LTD.
    Inventor: Takashi Mishima
  • Patent number: 9874559
    Abstract: Embodiments of the invention relate generally to devices and methods for pumping and controlling the flow of a fluid. More particularly, embodiments of the invention relate to capacitive pumping and flow control devices and methods. In one embodiment, the invention provides a pump system having an inlet valve, an outlet valve, and a chamber between and in communication with each of the inlet valve and the outlet valve, the chamber having at least one elastic surface, wherein the chamber will dilate in response to a fluid exerting a pressure on the elastic surface, contain a quantity of the fluid when so dilated, and discharge the quantity of the fluid through the opened outlet valve.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: January 23, 2018
    Assignee: INANOVATE, INC.
    Inventors: James Curtis Nelson, David Ure
  • Patent number: 9867939
    Abstract: Described are devices, systems, and methods for processing adipose tissue for reintroduction into a body. In some embodiments, adipose tissue is mixed with an additive prior to reintroduction.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: January 16, 2018
    Assignee: Allergan, Inc.
    Inventors: Justin Schwab, Mike Augarten, Darin Messina, Jason Metzner, Ethan Franklin
  • Patent number: 9795730
    Abstract: A blood treatment method is described that is adapted to at least partially eliminate the carbon dioxide content of the type comprising a step of drawing a blood flow. Advantageously according to the invention, the method further comprises the steps of: acidifying the blood flow with transformation of the related blood bicarbonate content into gaseous carbon dioxide; and eliminating the gaseous carbon dioxide content by means of a pressure gradient.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: October 24, 2017
    Assignee: Universitá Degli Studi di Milano-Bicocco
    Inventors: Antonio Maria Pesenti, Nicolo Antonino Patroniti
  • Patent number: 9592332
    Abstract: The present invention relates to a method of removing blood from an extracorporeal blood circuit following termination of a blood treatment session, wherein blood is concurrently removed both from an arterial conduit portion and from a venous conduit portion of the extracorporeal blood circuit. It further relates to a method for recognizing and/or eliminating air inclusions in or from an extracorporeal blood circuit and a treatment apparatus as well as a tube system.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: March 14, 2017
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Goetz Guenther, Joachim Manke
  • Patent number: 9579440
    Abstract: Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: February 28, 2017
    Assignee: OUTSET MEDICAL, INC.
    Inventors: Michael Edward Hogard, Gopi Lingam, Dean Hu, Balaji M. Maniam, James Ritson, Andy H. Uchida, John David Stienmier, Paul David McGregor
  • Patent number: 9364597
    Abstract: The present invention relates to a method as well as a blood treatment unit for the implementation of this method for the best possible attainment of a predetermined substitution target during the ultrafiltration of blood. According to the invention, a method and a blood treatment unit for the implementation of the method is provided, wherein it is determined by detection of pressure measurement values in the blood treatment unit whether the calculated substitution target is achieved at the end of the dialysis session or not and in case of the result that the calculated substitution target cannot be achieved with the current dialysis parameters, an adjustment of the flow rate of blood, dialysate and/or substituate is performed in order to achieve the substitution target for a given treatment time in an optimal way or modify the treatment time for the given substitution target as little as possible.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: June 14, 2016
    Assignee: B. BRAUN AVITUM AG
    Inventors: Henrik Wolff, Stefan Moll
  • Patent number: 9310232
    Abstract: The invention relates to a method for calibrating sensors, in particular RFID sensors, within an enclosure such as, e.g., a sterilization chamber. It furthermore relates to a sensor calibrated by the method of the invention, a disposable device including such a sensor, as well as a treatment device.
    Type: Grant
    Filed: February 24, 2009
    Date of Patent: April 12, 2016
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Alexander Heide, Klaus Metzner
  • Patent number: 9283311
    Abstract: An oxygenator includes: a housing; a hollow fiber membrane bundle stored in the housing and having multiple integrated hollow fiber membranes with a gas exchange function; a gas inlet portion and a gas outlet portion provided on the upstream and downstream of gas passages in lumens of the hollow fiber membranes, respectively; a blood inlet portion and a blood outlet portion provided on the upstream and downstream of blood passages outside the hollow fiber membranes, respectively; a first filter member provided on the hollow fiber membrane bundle in contact with a blood outlet portion side surface so as to cover substantially the entire surface and has a function to catch bubbles in blood; and a second filter member that is separated from the first filter member, positioned between the first filter member and the blood outlet portion, and has a function to catch bubbles in blood.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: March 15, 2016
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kazuhiko Takeuchi
  • Patent number: 9278168
    Abstract: An integrated centrifugal blood pump-oxygenator (1) which has a housing (2) with a top (3) having a blood inlet (4), a blood outlet (5) and a gas inlet (6), and a bottom (7) having a rotational body (8) being rotatably arranged in a rotor-housing (9) of the bottom (7). The integrated centrifugal blood pump-oxygenator (1) further has an oxygenator membrane (10) provided in an interior (11) of the housing (2), wherein in the operation state oxygen (12) is transferred from the gas inlet (6) through the oxygenator membrane (10) to a gas outlet (13) and blood (14) is brought in direct contact with the oxygenator membrane (10) by pumping the blood (14) with the rotational body (8) from the blood inlet (4) to the blood outlet (5). The rotational body (8) is magnetically journalled in a contact-free manner with respect to the rotor-housing (9). There is an extracorporeal life support system (1000), and a method of de-bubbling and priming a extracorporeal life support system (1000).
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: March 8, 2016
    Assignee: THORATEC LLC
    Inventors: Barry N. Gellman, Andrew Koert, Zhongjun Wu, Juntao Zhang, Bartley P. Griffith
  • Patent number: 9220834
    Abstract: A pressure sensor for a medical injection system includes a cuff, a transducer embedded in the cuff, and a force transmitting member coupled to the transducer and exposed at an inner surface of the cuff, such that an outer surface of a tubing line of a fluid circuit of the system, when fitted within the cuff, contacts the force transmitting member. A limited length of the tubing line may have a greater compliance than a remainder of the line, in which case, the pressure sensor cuff fits around and encloses the limited length to provide support against plastic deformation, when pressures within the line are significantly greater than atmospheric. The pressure sensor may detect whether or not the cuff is properly fitted around the tubing line, and/or determine a characteristic of the tubing line.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: December 29, 2015
    Assignee: ACIST Medical Systems, Inc.
    Inventor: Clinton Scott Vilks
  • Patent number: 9186451
    Abstract: The present invention relates to a method for priming a line for adding a medical solution, the line branching off a return line of an extracorporeal blood circuit, in particular a calcium line, a control device for controlling or regulating the method according to the present invention and a blood or plasma treatment apparatus with at least the control device according to the present invention. It further relates to a digital storage medium, a computer program product as well as a computer program.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: November 17, 2015
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Josef Beden, Olaf Kessel-Deynet, Juergen Klewinghaus, Thomas Pusinelli, Pascal Werner
  • Patent number: 9138527
    Abstract: A retrograde flow system is configured for treating an artery. The system includes an arterial access device adapted to be introduced into an artery and receive blood flow from the artery. A shunt fluidly is connected to the arterial access device, wherein the shunt provides a pathway for blood to flow from the arterial access device to a return site. A flow control assembly is coupled to the shunt and is adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. A shut-off valve assembly automatically blocks fluid flow through the shunt in response to injection of the fluid into the arterial access device.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: September 22, 2015
    Assignee: Silk Road Medical, Inc.
    Inventors: Richard J. Renati, Michi E. Garrison, Alan K. Schaer, Gregory M. Hyde
  • Patent number: 9050421
    Abstract: The invention relates to a calculation and control system for the determination of the state of a vascular access of a patient intended to follow successive sessions of extracorporeal blood treatment by extraction and return of the blood via the vascular access, the system comprising: means for determining the value of at least one hemodynamic extracorporeal parameter of the patient for at least two sessions; means for determining the value of the purification effectiveness of the treatment for at least two sessions; programmed means for determining a risk score relating to the state of the vascular access of the patient as a function of at least two values of the hemodynamic extracorporeal parameter and of at least two determined values of the purification effectiveness.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: June 9, 2015
    Assignee: Gambro Lundia AB
    Inventor: Bernard Bene
  • Patent number: 9039648
    Abstract: A dialysis system includes a dialysis fluid cassette-based membrane blood pump; a dialyzer in fluid communication with the blood pump: first and second dialysis fluid cassette-based balance chambers each having (i) a fresh dialysis fluid compartment in fluid communication with the dialyzer and (ii) a spent dialysis fluid compartment; a dialysis fluid cassette-based fresh dialysis fluid membrane pump in fluid communication with the fresh dialysis fluid compartments of the first and second balance chambers; a dialysis fluid cassette-based spent dialysis fluid membrane pump in fluid communication with the dialyzer and the spent dialysis fluid compartments of the first and second balance chambers; and arterial and venous lines in fluid communication with the dialyzer for patient connection, the arterial and venous lines each including a contact used for electrically detecting a patient access disconnection.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: May 26, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Thomas Kelly, Robert W. Childers, Don Busby, Rodolfo Roger, Waleed Mutasem El Sayyid, Shahid Din
  • Patent number: 9039647
    Abstract: A system or method automates and optimizes citrate anticoagulant supplementation in a blood filtration circuit during CRRT. A processor-based control system interfaces with a blood filtration circuit to detect patient blood flow into the circuit, detect fluid loss through a hemofilter, and sense vital electrolyte concentrations in the blood flow, and in response, control the addition of citrate, substitution fluid, and electrolyte supplements to ensure stability of plasma concentrations in post-dilution flow returned to the patient. The controller executes the method embodied as process control algorithms for calculating an optimal citrate flow rate as a function of selected, detected, and calculated system parameters. Citrate may be added to the circuit separately, or as part of a substitution solution or a dialysate.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: May 26, 2015
    Assignee: NIKKISO CO., LTD.
    Inventor: Jean-Michel Lannoy
  • Publication number: 20150141897
    Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include seven-stage de-airing of blood to provide automated cardiopulmonary replacement to sustain patient life during a medical procedure comprising repairing or replacing the heart valve in a patient.
    Type: Application
    Filed: September 23, 2014
    Publication date: May 21, 2015
    Inventors: Gerhard Muller-Spanka, Hans-Reinhard Zerkowski
  • Patent number: 9033908
    Abstract: The present invention relates to a device for the removal of toxic substances from dialysate fluid, blood or blood plasma, said device comprising i) a sorption-filter (E) for removing toxins, toxic solutes, toxic small and middle-sized molecules and protein bound toxins from the dialysate fluid, blood or bloodplasma, said sorption filter comprising a nanostructured material, a porous polymer matrix or a combination of the two, ii) an inlet (4) for entry of dialysate fluid, blood or blood plasma into said device, iii) an outlet (5) for the removal of purified dialysate fluid, blood or blood plasma from said device, and iv) a conduit connecting said inlet with said outlet and holding said sorption filter such that said dialysate fluid, blood or blood plasma is forced through said sorption filter.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: May 19, 2015
    Assignee: Nederlandse Organisatie voor toegepast—natuurwetenschappelijk onderzoek TNO
    Inventors: Stephanus Franciscus Schilthuizen, Lawrence Fabian Batenburg, Frank Simonis, Franky Flory Vercauteren
  • Patent number: 9024746
    Abstract: An automatic locking system for a medical treatment device helps to ensure that an assistant is present during treatment of a patient. Among the features disclosed biometric authentication to verify that a trained assistant is present, a presence detector to ensure the assistant is continuously present during treatment, and warning and recovery processes that allow intermittent lapses in the continuous presence of the assistant.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: May 5, 2015
    Assignee: Nxstage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, James M. Brugger
  • Patent number: 9011769
    Abstract: A blood reservoir may be used in combination with other elements such as a heart lung machine (HLM), oxygenator, heat exchanger, arterial filter and the like to form an extracorporeal blood circuit that may be employed in a procedure such as a bypass procedure. The blood reservoir may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field).
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: April 21, 2015
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Claudio Silvestri, Gabriele Tommasi
  • Patent number: 9005440
    Abstract: Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodialysis and electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source, an ED/EDI unit. The carbon source, urease source, and/or the ED/EDI unit can be in the form of removable cartridges.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: April 14, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Rongsheng Lin, Yuanpang Samuel Ding, James M. White, Ye Chen, Ying-Cheng Lo, Joshua Miller, Justin Rohde
  • Patent number: 8998837
    Abstract: An apparatus (1) for extracorporeal blood treatment comprising a blood treatment device (2) having a semipermeable membrane (5) which separates a blood chamber (3) from a fluid chamber (4). A used fluid line (7) connects the fluid chamber to a used fluid discharge. A first pump (8) controls the ultrafiltration through the semipermeable membrane. A second pump (9) arranged in the used fluid line downstream of the first pump keeps pressure between the first and the second pump at a constant predetermined value. The invention provides a protection system against any possible pressure change in the used fluid discharge in a hemodialysis or hemo(dia)filtration apparatus.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: April 7, 2015
    Assignee: Gambro Lundia AB
    Inventors: Massimo Fava, Mauro Suffritti, Anna Puppini
  • Patent number: 8992463
    Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: March 31, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Michael E. Hogard, Donald D. Busby, Robert W. Childers, Yuanpang Samuel Ding, Katherine M. Holian, Mark E. Jablonski, Thomas D. Kelly, Ying-Cheng Lo, Shincy J. Maliekkal, Rodolfo G. Roger, Donald A. Smith, Atif M. Yardimci
  • Patent number: 8986238
    Abstract: Systems and methods for salvaging blood cells from an absorbent material are disclosed. In one exemplary aspect, such as system includes a rotatable basin having perforations to allow rinse solution from a stationary basin to reversibly flow therethrough to wash the blood cells from the absorbent material, thereby forming an effluent solution. The system further includes a hemoconcentrator in fluid communication with the stationary basin having first and second fluid outputs for discharging a diluent solution and a blood cell discharge solution from the effluent solution respectively. The blood cells can be salvaged from the blood cell discharge solution. The second fluid output is in fluid communication with the stationary basin for recycling the diluent solution as the rinse solution.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: March 24, 2015
    Assignee: Cyclone Medtech, Inc.
    Inventor: Len Robinson
  • Patent number: 8979788
    Abstract: A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: March 17, 2015
    Assignee: DEKA Products Limited Partnership
    Inventors: Jason A. Demers, Larry B. Gray, James D. Dale, N. Christopher Perry, David E. Altobelli
  • Patent number: 8974405
    Abstract: A dialysis fluid cassette that includes a rigid body and a flexible backing covering a recessed portion of the rigid body to at least partially form a gas release chamber.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: March 10, 2015
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Thomas Irvin Folden, Martin Joseph Crnkovich, Christian Schlaeper, Lynn Jensen, Mohsen Reihanifam
  • Publication number: 20150056601
    Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the viability or one or more organs in a clinically dead organ donor or harvested donor organ for subsequent transplantation to an organ receiver patient.
    Type: Application
    Filed: July 30, 2014
    Publication date: February 26, 2015
    Inventors: Gerhard Muller-Spanka, Hans-Reinhard Zerkowski
  • Patent number: 8961445
    Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: February 24, 2015
    Assignee: Biomet Biologics, LLC
    Inventors: Douglas M. Arm, Michael Ponticiello, Surinder Mathur, Andrew G. Hood
  • Patent number: 8956317
    Abstract: In a single needle extracorporeal blood treatment apparatus, an ultrafiltration pump (10) performs a pure ultrafiltration of ultrafiltrate from an hemofilter (4). The blood may be continuously circulated through the hemofilter using a first pump (5), which alternates an higher flow rate during the arterial phase and a lower flow rate during the venous phase, and a second pump (6) which is maintained at a flow rate intermediate between said higher and lower flow rate. The apparatus may be used for treatment of Congestive Heart Failure.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: February 17, 2015
    Assignee: Gambro Lundia AB
    Inventor: Hiram Rada