Filter Means Patents (Class 604/6.09)
-
Patent number: 8974405Abstract: A dialysis fluid cassette that includes a rigid body and a flexible backing covering a recessed portion of the rigid body to at least partially form a gas release chamber.Type: GrantFiled: January 13, 2011Date of Patent: March 10, 2015Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Thomas Irvin Folden, Martin Joseph Crnkovich, Christian Schlaeper, Lynn Jensen, Mohsen Reihanifam
-
Publication number: 20150056601Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the viability or one or more organs in a clinically dead organ donor or harvested donor organ for subsequent transplantation to an organ receiver patient.Type: ApplicationFiled: July 30, 2014Publication date: February 26, 2015Inventors: Gerhard Muller-Spanka, Hans-Reinhard Zerkowski
-
Patent number: 8961445Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.Type: GrantFiled: January 10, 2013Date of Patent: February 24, 2015Assignee: Biomet Biologics, LLCInventors: Douglas M. Arm, Michael Ponticiello, Surinder Mathur, Andrew G. Hood
-
Patent number: 8956317Abstract: In a single needle extracorporeal blood treatment apparatus, an ultrafiltration pump (10) performs a pure ultrafiltration of ultrafiltrate from an hemofilter (4). The blood may be continuously circulated through the hemofilter using a first pump (5), which alternates an higher flow rate during the arterial phase and a lower flow rate during the venous phase, and a second pump (6) which is maintained at a flow rate intermediate between said higher and lower flow rate. The apparatus may be used for treatment of Congestive Heart Failure.Type: GrantFiled: February 28, 2013Date of Patent: February 17, 2015Assignee: Gambro Lundia ABInventor: Hiram Rada
-
Patent number: 8951219Abstract: A method includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the method.Type: GrantFiled: March 20, 2012Date of Patent: February 10, 2015Assignee: Medtronic, Inc.Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKalesh, Bryant Pudil
-
Patent number: 8951220Abstract: The present invention relates to an apparatus for making extracorporeal blood circulation available, in particular a heart-lung machine, comprising a venous connection and an arterial connection, between which a blood reservoir, a blood pump and a bubble detector for the detection of air bubbles are provided, with, downstream of the bubble detector, an arterial line leading to the arterial connection via an arterial clamp and a bypass leading via a bypass clamp back into the blood reservoir which is connected to a pump extracting air from the blood reservoir. In addition, the present invention relates to a method of operating such an apparatus.Type: GrantFiled: October 28, 2013Date of Patent: February 10, 2015Assignee: ZOLL LifeBridge GmbHInventors: Gerhard Brieske, Michael Brieske
-
Patent number: 8951484Abstract: Candidate cells, such as circulating tumor cells (CTCs), present with blood are captured using a multiple stage device, having successive stages configured to deviate candidate cells out of the blood while slowing down the flow rates of the deviated resultant for easier capture of CTCs through progressive stages. The devices can include separation channel and deviation channels formed of micro-post patterns dimensioned to deviate different desired candidate cells for analysis.Type: GrantFiled: January 31, 2013Date of Patent: February 10, 2015Assignee: The Regents of The University of MichiganInventors: Tommaso F. Bersano-Begey, Daniel F. Hayes
-
Patent number: 8945037Abstract: A blood purification apparatus has a dialyzer (1), an arterial blood circuit (2) with a blood pump 4, a venous blood circuit 3, a dialysate introduction line L1, a dialysate discharge line L2, a substitution line L3, and a substitution pump 9 that supplies the dialysate flowing in the substitution line L3 to the arterial blood circuit 2. A control device (11) estimates or measures the concentration of blood in a dilution channel section A. The control device (11) controls the volume of dialysate supplied by the substitution pump 9 on the basis of the estimated or measured blood concentration.Type: GrantFiled: September 24, 2012Date of Patent: February 3, 2015Assignee: Nikkiso Company LimitedInventors: Shinya Hasegawa, Masahiro Toyoda
-
Patent number: 8945036Abstract: The present invention includes a comprehensive replacement fluid system and method for the delivery of regional citrate anticoagulation (RCA) to extracorporeal blood circuits, wherein the system may include an online clearance monitor (OCM) and a circuit effluent online sensor system (OSS) for the continuous determination of patient plasma content of ultrafilterable solutes.Type: GrantFiled: February 14, 2012Date of Patent: February 3, 2015Assignee: Henry Ford Health SystemInventors: Balazs Szamosfalvi, Stanley Frinak, Jerry Yee
-
Patent number: 8939926Abstract: A system and method for removing gas bubbles from blood during circulatory assist procedures. An active filter apparatus forces the bubbles to the center of the system where they are removed from the blood before the blood exits the filter.Type: GrantFiled: May 28, 2013Date of Patent: January 27, 2015Assignee: Indian Wells Medical, Inc.Inventors: David W. Wieting, Jay A. Lenker
-
Patent number: 8932469Abstract: A dialysis machine includes a blood circuit, a dialysate circuit, and a dialyzer placed in communication with the blood circuit and the dialysate circuit. The dialysis machine includes a priming sequence in which dialysate is used to prime a first portion of the dialysate circuit and a physiologically compatible solution, other than dialysate, is used to prime a second portion of the dialysate circuit, the dialyzer and the blood circuit.Type: GrantFiled: January 9, 2012Date of Patent: January 13, 2015Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Robert W. Childers, Thomas D. Kelly, Rodolfo Roger
-
Patent number: 8926543Abstract: The invention provides a way of producing a natural immunologically active state in a person by subjecting him to an apheresis procedure with bioincompatible biomaterials for about one hour. To safely control the immunological shock induced by this procedure, the person is put under general anesthesia for about six hours, including the apheresis time and at least an additional five hours thereafter. This immunological activation is useful for treating malignant tumors and diseases related to immunosuppression, such as AIDS. The invention also provides for the use of an apheresis column containing a blood perfusion filter with bioincompatible materials for treating malignant tumors and infectious diseases.Type: GrantFiled: October 7, 2010Date of Patent: January 6, 2015Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Kazuhide Ohta, Hiroshi Miyamoto, Junji Takaba, Ako Nosé
-
Patent number: 8926551Abstract: Patients suffering from acute renal failure must be diagnosed and treated quickly so that a physician can confidently prescribe either peritoneal dialysis or hemodialysis. In one way of quickly treating the patients, software is used to calculate a suitable peritoneal dialysis prescription without regard to how short or how long a dialysis cycle is used, and without regard to a total dialysate fluid volume for a therapy. For patients with suitable peritoneal membrane transport properties, the software program suggests that, at least over a short period of time, unexpectedly high ultrafiltrate volumes and high clearances may be achieved.Type: GrantFiled: July 7, 2009Date of Patent: January 6, 2015Assignees: Baxter Healthcare Inc., Baxter Healthcare S.A.Inventors: Ying-Cheng Lo, Alp Akonur, Yuanpang S. Ding
-
Patent number: 8924458Abstract: This patent application relates generally to processing devices in the medical device area.Type: GrantFiled: November 29, 2012Date of Patent: December 30, 2014Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Roland Levin, Martin Joseph Crnkovich, Fei Wang, Michael Emmanuel Kotsos, Gregg Eric Fuhriman
-
Patent number: 8920356Abstract: A coupler includes a conductive polymer material that is so constructed and arranged to join tubing, wherein the conductive polymer material includes a conductive polymer component selected from the group consisting of polyaniline, polypyrrole, polythiophenes, polyethylenedioxythiophene, poly(p-phenylene vinylene) and mixtures thereof.Type: GrantFiled: June 30, 2011Date of Patent: December 30, 2014Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Sherwin Shang, Ramesh Wariar, Angel Lasso, George Lamberson, Dan F. Marcquenski, Jr., Jan Jensen, David Kuhn, Raf Castellanos
-
Patent number: 8915876Abstract: The present invention relates to a method for removing blood from an extracorporeal blood circuit and/or a functional device, each connectable or connected with a blood treatment apparatus for the purpose of blood treatment of a patient. The blood treatment apparatus of the method comprises or is connected with at least one extracorporeal blood circuit with a line having interior portions, the extracorporeal blood circuit comprising at least one arterial line section and at least one venous line section, wherein a first section of the arterial line section is configured to be connected with a second section of the venous line section, and further comprises at least one blood pump for conveying blood within the line interior portions. The method includes the step of operating the blood pump in a second conveying direction which is opposite to a first customary conveying direction. It further relates to corresponding apparatuses.Type: GrantFiled: July 27, 2012Date of Patent: December 23, 2014Assignee: Fresenius Medical Care Deutschland GmbHInventors: Soeren Gronau, Juergen Haecker, Ralf Mueller, Manfred Weis, Stefan Kreber, Martin Thys
-
Patent number: 8911666Abstract: A filter member used in an oxygenator is constructed to provide improved contact with a hollow fiber membrane bundle and to capture bubbles contained in blood. The filter member possesses elasticity at least in the circumferential direction to allow the inner circumference of the filter member to be increased from a natural non-expanded state prior to placement on the hollow fiber membrane bundle to an expanded state in which the inner circumference of the filter member is increased when placed on the hollow fiber membrane bundle. The filter member is constructed to satisfy the condition 0.5?L2/L1<1, wherein L1 represents the outer circumference of the hollow fiber membrane bundle and L2 represents the inner circumference of the filter member in the natural non-expanded state.Type: GrantFiled: March 8, 2013Date of Patent: December 16, 2014Assignee: Terumo Kabushiki KaishaInventors: Kazuhiro Mizoguchi, Eiji Kato
-
Patent number: 8905960Abstract: A device for the filtration of a complex fluid composition such as blood, includes a base (12) with a bottom (18), a top (14) with a bottom (30), and a membrane (16) that is arranged between the base and the top so as to define a low chamber C1 and a high chamber C2, with an input tap (26) of the complex composition that is to be filtered emptying into the low chamber C1, an output tap (28) of the retentate with elements for adjusting the flow rate emptying into this same low chamber C1, and an output tap (36, 36-1) of the high chamber C2, whereby this output tap (36, 36-1) of the permeate is subjected to negative pressure.Type: GrantFiled: May 14, 2009Date of Patent: December 9, 2014Assignee: Direction et PrioritesInventors: Francis Gadrat, Bertrand Chastenet
-
Publication number: 20140358060Abstract: A system for filtering or treating blood of a subject is provided herein. The system includes a bone port for establishing fluid communication with a bone marrow of the bone and a return port for returning blood from the bone marrow to a circulation of the subject. The system further includes a blood treatment or filtering device interposed between the bone and return ports thereby establishing a mini-circulatory system.Type: ApplicationFiled: December 27, 2012Publication date: December 4, 2014Inventor: Morris Laster
-
Publication number: 20140358061Abstract: An apparatus is described for extracorporeal blood treatment comprising an extracorporeal circuit (2), a first pump (13) operating at the removal line (3) of the blood, a second pump (14) operating at the return line (7) of the blood to the patient, a first blood reservoir (21) operating on the blood return line (7) upstream of the second blood pump (14) and a sensor (22) predisposed to detect at least a parameter, for example the pressure in the first reservoir; a control unit (100) connected to the first pump (13), to the second pump (14) and to the sensor (22) is configured such as to control the first pump (13) to promote removal of the blood along the removal line and the movement of the second pump (14) to promote the return of the blood to the patient along the return line, the control of the second pump being carried out on the basis of the signal emitted by the sensor acting on the first reservoir.Type: ApplicationFiled: December 27, 2012Publication date: December 4, 2014Inventors: Rocco Cappella, Mirco Lancellotti
-
Patent number: 8900173Abstract: A blood purification apparatus has a dialyzer (1), an arterial blood circuit (2) with a blood pump (4), a venous blood circuit (3), a dialysis fluid introduction line (L1), a dialysis fluid discharge line (L2), a dialysate infusing line (L8), and a dialysate infusing pump (13). A closed circuit is formed in the flow route of the dialysis fluid on the dialysis fluid introduction line (L1) side including a predetermined part where a collection port (11) is formed. A testing process is performed to confirm the connection of the dialysate infusing line (L8) to the collection port (11) by measuring fluid pressure within the closed circuit while driving the dialysate infusing pump (13).Type: GrantFiled: August 8, 2012Date of Patent: December 2, 2014Assignee: Nikkiso Company LimitedInventor: Akira Sugioka
-
Patent number: 8900462Abstract: A leukocyte-removing filter, characterized in that it comprises a filter material having a vertical permeation coefficient (kx) of 0.5×10?12 to 2.0×10?12 m2 and a ratio (ky/kx) of a horizontal permeation coefficient (ky) to kx of 0.5 to 1.5; and a method for removing leukocytes using said filter. The above leukocyte-removing filter has a higher leukocyte-removing performance per unit volume and also does not bring clogging nor increase of pressure drop.Type: GrantFiled: June 9, 2005Date of Patent: December 2, 2014Assignee: Asahi Kasei Medical Co., LtdInventors: Yukihiro Yamada, Yukihiko Uchi
-
Patent number: 8882693Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include seven-stage de-airing of blood to provide automated cardiopulmonary replacement to sustain patient life during a medical procedure comprising repairing or replacing the heart valve in a patient.Type: GrantFiled: December 7, 2010Date of Patent: November 11, 2014Assignee: ZOLL LifeBridge GmbHInventors: Gerhard Müller-Spanka, Hans-Reinhard Zerkowski
-
Patent number: 8875748Abstract: An apparatus for the filling of a medical filter has at least one first space and one second space which are semipermeably separated by one or more membranes, with the spaces each having at least one inflow and outflow. The apparatus includes a detection unit having a first element and a second element, with a liquid discharge from at least one of the first and second spaces being detectable by the first element, and the state of the filling of the filter being determinable by the second element with reference to the detected liquid discharge. A method of filling a medical filter employs the apparatus.Type: GrantFiled: September 2, 2009Date of Patent: November 4, 2014Assignee: Fresenius Medical Care Deutschland GmbHInventors: Josef Beden, Itka Bado, Georg Verch
-
Patent number: 8877062Abstract: The invention relates to extracorporeal blood circuits, and components thereof (e.g., hollow fiber membranes, potted bundles, and blood tubing), including 0.005% to 10% (w/w) surface modifying macromolecule. The extracorporeal blood circuits have an antithrombogenic surface and can be used in hemofiltration, hemodialysis, hemodiafiltration, hemoconcentration, blood oxygenation, and related uses.Type: GrantFiled: July 12, 2010Date of Patent: November 4, 2014Assignee: Interface Biologics, Inc.Inventors: Sanjoy Mullick, Weilun Chang, Hanje Chen, Mark Steedman, Roseita Esfand
-
Publication number: 20140323943Abstract: A dialysis device according to the invention includes a hemodialyzer which is connectable to the blood circulation of a patient, a plasma storage device for temporary storage of blood plasma of the patient and a supply device for supplying blood plasma stored in the plasma storage device into the blood circulation of the patientType: ApplicationFiled: January 28, 2014Publication date: October 30, 2014Inventor: Werner Kleophas
-
Patent number: 8865172Abstract: A method for reducing the number of selected antibodies in a subject's blood, the method comprising removing blood from the subject, passing the blood along an enclosed pathway, wherein the pathway comprises one or more semi-permeable hollow fibers with one or more membranes having surfaces positioned substantially perpendicular to the length of the one or more hollow fiber and antigens specific for the antibodies immobilized on the one or more membranes, returning the treated blood to the internal circulation of the subject, wherein the returned treated blood has a reduced number of selected antibodies compared to before treatment.Type: GrantFiled: June 25, 2010Date of Patent: October 21, 2014Assignee: Advanced Extravascular Systems, Inc.Inventor: Duke K. Bristow
-
Patent number: 8865067Abstract: A combination oxygenator and arterial filter device for treating blood in an extracorporeal circuit includes a housing, an oxygenator, and a depth filter. The oxygenator includes a hollow fiber bundle forming an oxygenator exterior face. The depth filter is disposed (e.g., wound) directly over the exterior face, and includes a plurality of filaments arranged to define filter layers of level wound filaments. A first layer directly abuts the oxygenator exterior face. The oxygenator bundle differs from the depth filter in terms of: fiber and filament materials, construction of the fibers and filaments, and/or minimum gap spacings between axially adjacent ones of the fibers and the filaments. An oxygenator with integrated arterial filtering capability is provided that minimally impacts the extracorporeal blood circuit prime volume.Type: GrantFiled: April 29, 2011Date of Patent: October 21, 2014Assignee: Medtronic, Inc.Inventors: Robert Olson, John L. Knoll
-
Patent number: 8858487Abstract: A blood purification apparatus, during priming, has one end of the fluid infusing line L3 connected at the same location as the connected location of the fluid infusing line L3 during the blood purification treatment process. Determining whether either a pre-fluid infusion, where replenishment fluid is supplied to an arterial air trap chamber 5, or a post-fluid infusion, where the replenishment fluid is supplied to a venous air trap chamber 6, will be performed in the blood purification treatment process. The end of an arterial blood circuit 2 and the end of a venous blood circuit 3 are connected together to communicate fluid. In addition, a blood pump 4 is driven in normal rotation or in reverse rotation direction while the replenishment fluid is supplied from the fluid infusing line L3. The replenishment fluid is discharged from an overflow line 6a.Type: GrantFiled: August 8, 2012Date of Patent: October 14, 2014Assignee: Nikkiso Company LimitedInventor: Tomohiro Suzuki
-
Patent number: 8858880Abstract: Treatment of carbon monoxide poisoning of a body by removal of a portion of the blood from the body, placing the portion in an exposure cell, exposing the portion in the cell to light of wave length and intensity that causes dissociation of carbon monoxide from hemoglobin, and returning the portion to the body. The intensity and wave length of the light is sufficient to dissociate a therapeutically-effective amount of carbon monoxide from the hemoglobin in the blood. The blood is circulated from and to the body through a concentric double lumen cannula. The wave lengths of the light are 540 and/or 570 nanometers. The cell exposes the blood to at least 9.5 Joules of dissociative light per milliliter of blood, and least 9.5 Watts of dissociative light per milliliter of blood per second. Oxygen is provided to, and the dissociated carbon monoxide is removed from the system.Type: GrantFiled: February 13, 2012Date of Patent: October 14, 2014Inventor: Mark S. Smyczynski
-
Patent number: 8858486Abstract: A method for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part during an extracorporeal blood treatment is disclosed, where the blood to be treated flows in an extracorporeal blood circuit through a blood chamber of a dialyzer split by a semi-permeable membrane into the blood chamber and a liquid chamber, and dialysis liquid flows in a dialysis liquid path through the dialysis liquid chamber of the dialyzer. A device for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part, and a blood treatment device including such a device are also disclosed. The method and device are based on the fact that the sum of the fistula recirculation and the cardiopulmonary recirculation part, i.e. the total recirculation, is determined for two blood flow rates which differ from each other. The fistula recirculation and/or the cardiopulmonary recirculation part are then determined from the recirculation for the two blood flow rates.Type: GrantFiled: November 22, 2008Date of Patent: October 14, 2014Assignee: Fresenius Medical Care Deutschland GmbHInventors: Wei Zhang, Elke Schulte, Christoph Bardorz
-
Patent number: 8852135Abstract: A method is provided for monitoring the introduction of substitution fluids for an extra-corporeal blood processing device with an extra-corporeal blood circuit, comprising an arterial blood line, running from an arterial patient connection to a first chamber of a dialyzer or filter divided into said first chamber and a second chamber by a membrane and a venous blood line, running from the first chamber of the dialyzer or filter to a venous patient connection. A device is provided for monitoring the introduction of substitution fluids for an extra-corporeal blood processing unit with an extra-corporeal blood circuit and an extra-corporeal blood processing device with a device for monitoring the introduction of substitution fluids. The method and the device for monitoring the introduction of substitution fluids are based on monitoring the fluid level in the bubble trap, arranged in the venous blood line of the extra-corporeal blood circuit.Type: GrantFiled: October 8, 2009Date of Patent: October 7, 2014Assignee: Fresenius Medical Care Deutschland GmbHInventors: Josef Beden, Itka Bado, Georg Verch
-
Patent number: 8852433Abstract: Device (5) for filtering blood including a filter unit (7) having a blood filter, an inlet (8) for blood to be filtered and being connectable to an artery of a patient and a blood outlet (9) for filtered blood and being connectable to a vein of the patient, and having a filtrate container (6,14), that encloses the filter unit (7), for receiving filtrate (12) passing through the blood filter during a filtering process and that the filtrate container (6,14) is a closed container, which in a filled state is arranged to establish a counter-pressure over the blood filter, whereby the filtering process is interrupted. The invention also concerns a system including the above device.Type: GrantFiled: December 4, 2013Date of Patent: October 7, 2014Assignee: Gambro Lundia ABInventor: Anders Nilsson
-
Patent number: 8834720Abstract: Apparatus and methods for the extracorporeal treatment of blood are described. The apparatus includes a dialyzer which is separated into a first and second chamber by a semipermeable membrane, wherein the first chamber is disposed in a dialysis fluid path and the second chamber can be connected to the blood circulation of a patient by way of a blood inflow conduit and a blood outflow conduit, a feed for fresh dialysis fluid, a discharge for spent dialysis fluid, a measuring device disposed within the discharge for determining the absorption of the spent dialysis fluid flowing through the discharge, wherein the measuring device has at least one radiation source for substantially monochromatic electromagnetic radiation, and a detector system for detecting the intensity of the electromagnetic radiation, wherein means are provided to compensate for changes that occur in the intensity of the electromagnetic radiation of the radiation source and/or the sensitivity of the detector system.Type: GrantFiled: February 5, 2010Date of Patent: September 16, 2014Assignee: B. Braun Avitum AGInventor: Joern Ahrens
-
Patent number: 8834719Abstract: A dialysis machine method includes in an embodiment applying a pneumatic closing pressure to a first valve chamber and arranging a compliance chamber to flex and absorb energy from the pneumatic closing pressure so as to tend to prevent the pneumatic closing pressure from opening an existing closure of a second valve chamber.Type: GrantFiled: December 19, 2011Date of Patent: September 16, 2014Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Robert W. Childers, Thomas D. Kelly, Rodolfo Roger
-
Patent number: 8834399Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the viability or one or more organs in a clinically dead organ donor or harvested donor organ for subsequent transplantation to an organ receiver patient.Type: GrantFiled: December 7, 2010Date of Patent: September 16, 2014Assignee: ZOLL LifeBridge GmbHInventors: Gerhard Muller-Spanka, Hans-Reinhard Zerkowski
-
Patent number: 8827943Abstract: In one aspect, the invention provides a device comprising a catheter. In another aspect, the invention provides a method of removing an agent from blood.Type: GrantFiled: March 14, 2013Date of Patent: September 9, 2014Assignee: University of Pittsburg—Of The Commonwealth System of Higher EducationInventors: George Oliviu Angheloiu, John A. Kellum, Jr., William D. Anderson, Catalin Toma
-
Patent number: 8827942Abstract: The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfils at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage device, a computer program product, and a computer program.Type: GrantFiled: October 21, 2010Date of Patent: September 9, 2014Assignee: Fresenius Medical Care Deutschland GmbHInventors: Paul Chamney, Ulrich Moissl, Peter Wabel, Volker Nier, Sebastian Wieskotten
-
Patent number: 8815088Abstract: According to the present invention, a dialysis fluid pump comprises: a housing having an accommodating space formed therein; a dialysis fluid supply tube and a dialysis fluid recovery tube, at least a portion of each of which is accommodated in the accommodating space; a cam rotatably installed in the accommodating space; a motor for rotating the cam; and a first backflow pressure preventer and a second backflow pressure preventer adapted to be mobile in the accommodating space and be pushed by the cam. The dialysis fluid supply tube is made of a flexible material which can be contracted or relaxed, and one end thereof is connected to a dialysis fluid supply tank and the other end thereof is connected to a hemodialysis filter. The dialysis fluid recovery tube is made of a flexible material which can be contracted or relaxed, and one end thereof is connected to a dialysis fluid recovery tank and the other end thereof connected to the hemodialysis filter.Type: GrantFiled: January 17, 2011Date of Patent: August 26, 2014Assignees: Ancbio Co., Ltd.Inventors: Nak-Myung Choi, Kyungsoo Lee, Cho Hay Mun, Sa Ram Lee, Dong Wook Lee, Byoung-Goo Min, Jong-Weon Choi
-
Patent number: 8815095Abstract: An artificial kidney that regenerates dialysate includes: a catheter having an inflow lumen and an outflow lumen for communication with a peritoneal cavity of a patient; a fluid circuit in fluid communication with the catheter for circulating dialysate into, through and out of the peritoneal cavity; a pump configured to circulate the dialysate; a cleaning cartridge coupled to the fluid circuit for removing solutes from the dialysate, including a therapeutically effective amount of urea from the dialysate as the dialysate circulates along the fluid circuit; and wherein the fluid circuit is configured to receive a volume of ultrafilterate removed from the patient, such that the pump can mix the ultrafiltrate volume with the dialysate to an increase an overall therapy fluid volume.Type: GrantFiled: September 18, 2009Date of Patent: August 26, 2014Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventor: Brian R. Micheli
-
Patent number: 8808645Abstract: Molecular filters are disclosed herein. An example of the molecular filter includes a rolled substrate having an interior surface and opposed ends that are substantially orthogonal to the interior surface. The rolled substrate defines a layer and a fluid flow path extending from one of the opposed ends to another of the opposed ends. A template is positioned on the interior surface of the rolled substrate. The template includes a matrix, and molecule template locations formed in the matrix.Type: GrantFiled: October 25, 2011Date of Patent: August 19, 2014Assignee: Hewlett-Packard Development Company, L.P.Inventors: Warren Jackson, Zhiyong Li
-
Patent number: 8808551Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.Type: GrantFiled: November 15, 2010Date of Patent: August 19, 2014Assignee: Biomet Biologics, LLCInventors: Michael D. Leach, Joel C. Higgins, Matthew Swift, Nathan Gordon
-
Patent number: 8808977Abstract: The present invention relates to a method for illuminating the viruses in a circulatory blood, comprising the following steps of: 1) Adding an anticoagulant into a whole blood source and establishing a circulation system for the whole blood source; 2) Withdrawing the whole blood with the anticoagulant into a plasma-separating device for a separation, when finished, directly pumping the red-blood cells back into the whole blood source and transporting the plasma into a mixing transport pump after the separation; 3) Meanwhile, pumping a photosensitizer methylene blue into the mixing transport pump so that the methylene blue is mixed with the plasma and pumped together into a plasma container; 4) Using an illumination device to illuminate the plasma in the plasma container for virus illumination, and pumping the virus-illuminated plasma into a removing device for removing off the photosensitizer; 5) The methylene blue being absorbed by the removing device and the plasma illuminated being transfused back into theType: GrantFiled: May 21, 2004Date of Patent: August 19, 2014Assignee: Beijing Jingjing Medical Equipment Co., LtdInventors: Weixing Wu, Yuen Kam
-
Patent number: 8801646Abstract: An extracorporeal blood system includes: an extracorporeal blood machine; an arterial line extending from the extracorporeal blood machine; a venous line extending from the extracorporeal blood machine; and an access disconnection circuit for detecting a disconnection of at least one of the arterial or venous lines from a patient, the access disconnection circuit including (i) a signal generation source having first and second signal generation source electrical lines each in electrical communication with blood traveling through one of the arterial or venous lines, (ii) a conductive pathway electrically communicating blood traveling through the arterial line with blood traveling through the venous line, and (iii) a signal processing unit positioned and arranged to process a signal generated by the source to detect the disconnection of the at least one of the arterial and venous lines.Type: GrantFiled: December 10, 2012Date of Patent: August 12, 2014Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: James Han, Thomas P. Hartranft, Thomas D. Kelly, Angel Lasso
-
Patent number: 8795517Abstract: A machine-readable medium with instructions for pumping blood from a patient's blood stream into an access line, introducing an anticoagulant solution into the pumped blood, filtering the pumped blood and delivering it to a return line, introducing a substitution fluid into the pumped blood, introducing a calcium and magnesium solution into the blood traveling through the return line, and returning the blood back to the patient's blood stream.Type: GrantFiled: August 6, 2013Date of Patent: August 5, 2014Assignee: Nikkiso Co., Ltd.Inventor: Jean-Michel Lannoy
-
Patent number: 8795218Abstract: A method of removing unwanted molecules from blood includes (i) directing a flow of blood from a patient through a first hemofilter, (ii) removing a volume of fluid from the blood using the first hemofilter, (iii) combining a volume of first substitution fluid with an outflow from the first hemofilter, the volume of first substitution fluid being substantially equal to the volume of fluid removed from the blood using the first hemofilter, (iv) directing the combined first hemofilter outflow and the first substitution fluid volume from the first hemofilter through a second hemofilter, (v) combining a second substitution fluid with outflow from the second hemofilter, and (vi) returning the combined second hemofilter outflow and the second substitution fluid volume from the second hemofilter to the patient.Type: GrantFiled: August 5, 2013Date of Patent: August 5, 2014Assignee: Nikkiso Co., Ltd.Inventor: Jean-Michael Lannoy
-
Patent number: 8784654Abstract: Filtration devices for collection and filtration of biological samples are disclosed. Devices having a filtration element oriented in a generally vertical orientation are provided, as well as filtration devices that incorporate a cooling mechanism to reduce the temperature of collected solids. Tissue collection devices, such as aspiration assemblies, tissue sampling devices, and the like incorporating filtration devices are disclosed. Methods of collecting biological samples and separating biological solids from a liquid/solids mixture are also disclosed, together with analytical techniques and protocols for analyzing biological samples.Type: GrantFiled: November 14, 2008Date of Patent: July 22, 2014Assignee: Bayer Medical Care, Inc.Inventor: Edward I. Wulfman
-
Publication number: 20140190887Abstract: A method for cleaning a blood filter includes: (i) pumping a physiologically safe fluid back and fourth through the insides and/or the outsides of a plurality of hollow fiber membranes of the blood filter to remove or loosen blood residuals, such as blood clots, proteins and/or biological fluid; (ii) injecting air into the physiologically safe fluid to form an air/fluid mixture; (iii) pumping the air fluid mixture through the insides and/or outsides of the plurality of the hollow fiber membranes of the blood filter to further or remove or loosen blood residuals therefrom; and (iv) removing the air/physiologically safe fluid mixture along with the removed or loosened blood residuals to drain.Type: ApplicationFiled: January 8, 2013Publication date: July 10, 2014Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.Inventors: Justin Rohde, Derek Wiebenson
-
Patent number: 8771516Abstract: Permselective asymmetric membranes suitable e.g. for hemodialysis, hemodiafiltration and hemofiltration of blood, and having improved performance, including improved sieving characteristics, providing enhanced removal of middle molecular weight substances, e.g. inflammatory mediators having a molecular weight between 20 and 40 kDa. The improved sieving characteristics are due to a narrow pore size distribution of the membranes created in the production process. Processes for the preparation of these membranes, devices comprising these membranes, and the use of these membranes in hemodialysis, hemodiafiltration and hemofiltration of blood, as well as in bioprocessing, plasma fractionation and the preparation of protein solutions.Type: GrantFiled: May 19, 2010Date of Patent: July 8, 2014Assignee: Gambro Lundia ABInventors: Bernd Krause, Carina Zweigart, Heinrich Behr
-
Patent number: 8771215Abstract: A machine (1) for extracorporeal blood treatment comprises a device (2) for ultrafiltration of a liquid through a semi-permeable membrane (3) of a blood treatment device (4), a first sensor (11) for ultrafiltration rate through the membrane, a second group of sensors (13) for measuring a trans-membrane pressure, an infusion line (16) with an infusion pump (17) and a programmed controller (14) for calculating a maximum infusion rate as a function of the transmembrane pressure. The machine is suitable for kidney failure treatments, such as hemofiltration and hemodiafiltration. In a relatively short time the machine enables a large quantity of corporeal blood to be removed from the patient.Type: GrantFiled: December 20, 2011Date of Patent: July 8, 2014Assignee: Cambro Lundia ABInventors: Claudio Tonelli, Bernd Wittner, Werner Beck, Helmut Hildwein, Reinhold Deppisch, Jonas Svensson, Bjorn Ericson