Eject Means Moved By Force Applied To Trigger Associated With Pistol Grip Patents (Class 604/61)
  • Patent number: 11998466
    Abstract: A valve loading system that uses a valve loader to transfer a valve or other medical device from a storage cartridge into a deployment catheter. The valve or other medical device can be implanted or positioned within a patient using the catheter after the valve or other medical device has been compressed and loaded into the catheter using the valve loader. The process then can be repeated by using the valve loading system to load or introduce another valve or other medical device into the catheter. The valve loading system includes a loading pin sized to limit contact with the medical device during a loading procedure.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: June 4, 2024
    Assignee: Gyrus ACMI, Inc.
    Inventors: Peter A. Lambe, Ryan Ponten, Jeffrey S. Tweedy
  • Patent number: 11752264
    Abstract: An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: September 12, 2023
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 11730513
    Abstract: Aspects of the present disclosure are directed toward apparatuses, methods, and systems comprising an introducer for facilitating subcutaneous implantation of a medical device. The introducer includes a housing, a tunneler extending from the housing, an inserter configured to move along a pathway to pass the medical device through the housing, a compartment configured to releasably hold and contain the medical device prior to the inserter moving the medical device, and a snap-feature integrally formed by the housing.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: August 22, 2023
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Serge Dubeau, Tyler Thompson, Kathryn Sick
  • Patent number: 11612729
    Abstract: An implant injection device includes an injection needle, a receiver housing receiving at least a first implant and a second implant, an injection mechanism, including a pushing rod arranged upstream from the implants and configured to push the implants through the injection needle between an initial position and a final position in which the implants are injected, a pushing device for pushing on the pushing rod, configured to exert a force to move the pushing rod from the initial position to the final position, an intermediate stop device holding the pushing rod in an intermediate position and opposing the force exerted by the pushing device when a stroke of the pushing rod reaches a predetermined distance corresponding to a length of injection of the first implant, and an actuator for actuation by a user, configured to release the pushing rod from the intermediate position to the final position.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: March 28, 2023
    Inventors: Gaëtan Painchaud, Pascal Dugand, Thomas Megard
  • Patent number: 11426530
    Abstract: An injection device comprises a housing for holding a syringe that has a needle at one end and (ii) a cap that is removably attached to the housing and that has a needle shield to cover said needle. The cap further comprises an actuator and a gear assembly comprising first and second linear gears and a double gear. The gear assembly is configured such that movement of the first linear gear in a first direction rotates the double gear to drive the second linear gear to urge the needle shield away from the housing. The actuator is configured to move the first linear gear in the first direction.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: August 30, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Peter Nober, Matthias Rau, David Theysen
  • Patent number: 11420032
    Abstract: A magazine for accommodating pellets for use in an injector includes a barrel comprising a hollow cylindrical compartment with an open front end and an open rear end. The cross-section of the compartment is selected to accommodate a pellet. The cross section of the rear end is smaller than the accommodated pellet so that it cannot be extracted from the rear end of the compartment. The magazine further includes a cover for closing the front end, including a dispensing opening which, in the closed state, is positioned in front of the front end and has a cross-section selected such that the pellet can pass through the dispensing opening. At least one bar projecting into the dispensing opening prevents the pellet from accidentally falling out, and when subjected to a predetermined force, can be bent outwards such that the pellet can be delivered through the dispensing opening.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: August 23, 2022
    Assignee: Henke-Sass, Wolf GmbH
    Inventors: Melanie Eisele, Stefan Knefel
  • Patent number: 11344435
    Abstract: A system for repairing a glenoid defect of a specific patient can include a patient-specific punch and a patient-specific shaping block. The patient-specific punch can form a patient-specific glenoid implant from a bone puck. The patient-specific shaping block can shape the patient-specific glenoid implant to match and fill a glenoid defect of a specific patient.
    Type: Grant
    Filed: March 4, 2020
    Date of Patent: May 31, 2022
    Assignee: Biomet Manufacturing, LLC
    Inventors: Nathan A. Winslow, Michael Francis Kovacs, John Schulz
  • Patent number: 11344712
    Abstract: An implant injection device, including an injection needle, a receiver housing for receiving at least one implant, an injection mechanism, the injection mechanism including a pushing rod, arranged upstream from the at least one implant housed in the receiver housing, extending longitudinally and configured to push the at least one implant through the injection needle between an initial position and a final position in which the at least one implant is injected, a mechanism for actuation by a user, configured to actuate a displacement of the pushing rod from the initial position to the final position, the mechanism for actuation including a rack transmission mechanism.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: May 31, 2022
    Inventors: Gaëtan Painchaud, Pascal Dugand, Thomas Megard
  • Patent number: 11292025
    Abstract: A material dispense tip includes an elongated hole in an elongated neck that extends from an input end of the neck to an output end of the neck. The hole at the output end of the neck has a first diameter. The output end of the neck is positioned against a die surface. A punch is inserted into the hole at the input end of the neck. An external force is applied to the neck to cause the output end of the neck to be deformed under compression by the die surface, to reduce the diameter of the hole at the output end of the neck from the first diameter to a second diameter that is less than the first diameter.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: April 5, 2022
    Assignee: DL Technology, LLC.
    Inventor: Jeffrey P. Fugere
  • Patent number: 11058819
    Abstract: An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: July 13, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 10973656
    Abstract: The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectively detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area. In one embodiment, the integrated fusion cage is an expandable integrated fusion cage.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: April 13, 2021
    Assignee: Spinal Surgical Strategies, Inc.
    Inventors: Jeffrey B. Kleiner, Edward John Grimberg
  • Patent number: 10695544
    Abstract: An insufflation pump includes a pump body having a first end and a second end. The pump body includes a syringe mechanism at the first end and an actuation mechanism at the second end. The syringe mechanism includes a plunger. The plunger of the syringe mechanism and the actuation mechanism are linked by a toggle assembly facilitating transfer of power from the actuation mechanism to the syringe mechanism.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: June 30, 2020
    Assignee: Miller Medical LLC
    Inventor: Stuart H Miller
  • Patent number: 10548590
    Abstract: A system for repairing a meniscus includes a suture that includes a first anchor, a second anchor, and a flexible portion connecting the first anchor and the second anchor. The flexible portion includes a self-locking slide knot between the first anchor and the second anchor. The system also includes a needle having a longitudinal extending bore and an open end. The bore is configured to receive the first anchor and the second anchor. The system further includes a body portion operatively connected to the needle at a distal end of the body portion. The body portion has a lumen. The system also includes a pusher configured to rotate and slide within the lumen of the body portion and the longitudinal extending bore of the needle. The pusher has first and second stop surfaces, each of which is constructed and arranged to engage a proximal end of the body portion.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: February 4, 2020
    Assignee: Ivy Sports Medicine, LLC
    Inventors: Stephen Vaughan Harris, Nadine Beverly Nelson
  • Patent number: 10537724
    Abstract: An injection device for injecting a solid dose formulation into a human or animal body, the injection device comprising an actuator (10) having a cassette mounting portion (14); a cassette holder (20) having a cassette storage portion; and a cassette selectively movable between the cassette storage portion and the cassette mounting portion, wherein, the cassette (34) comprises a solid dose formulation and the actuator is receivable in the cassette holder to selectively move the cassette between the cassette storage portion and the cassette mounting portion.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: January 21, 2020
    Assignee: ENESI PHARMA LIMITED
    Inventors: Colin Conlon, Derek Fenlon, Pascal Launois, Martina Moyne, Owen William Ryan
  • Patent number: 10524824
    Abstract: Devices and methods are described for penetrating hard plaque that partially or completely occludes blood vessels and disturbs blood flow through the blood vessel. The device includes a distal pre-loaded spring that can store energy and release it as impact at the device distal tip, in order to penetrate or break through hard plaque that is blocking blood path in blood vessels.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: January 7, 2020
    Assignee: Upstream Peripheral Technologies Ltd.
    Inventors: Dan Rottenberg, Yosi Pesis
  • Patent number: 10507052
    Abstract: A handling device for handling an augmentation implant is proposed, comprising an elongated housing having an axial through-bore for accommodating a sonotrode of an ultrasound applicator, and a lateral opening for inserting a pin magazine with an augmentation pin, wherein the axial through-bore and the lateral opening are connected to each other. The handling device further comprises a distal implant portion for fastening a proximal end of the augmentation implant at the housing, and a proximal tool portion for driving and/or augmenting the augmentation implant.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: December 17, 2019
    Assignees: Woodwelding AG, Stryker European Holdings I, LLC
    Inventors: Helge Giersch, Jörg Mayer, Andrea Müller
  • Patent number: 10441450
    Abstract: In apparatus and methods for rapid deployment of tissue anchors, a tissue manipulation assembly has a pivoting jaw. A needle assembly can be advanced through the launch tube across tissue received between the jaw members of the tissue manipulation assembly. Tissue anchors can be advanced through the needle assembly for securing received tissue. The tissue anchors can be positioned within a reloadable chamber of a control handle disposed outside the patient, then advanced through the needle assembly.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: October 15, 2019
    Assignee: USGI Medical, Inc.
    Inventors: Vahid Saadat, Cang C. Lam
  • Patent number: 10328205
    Abstract: A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: June 25, 2019
    Assignee: SHL Medical AG
    Inventor: Slobodan Stefanov
  • Patent number: 10245159
    Abstract: The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectively detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area. In one embodiment, the integrated fusion cage is an expandable integrated fusion cage.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: April 2, 2019
    Inventors: Jeffrey B. Kleiner, Edward John Grimberg
  • Patent number: 10219882
    Abstract: A pill delivery device comprising a grip, barrel and trigger assemblies. The pistol style device contains a tension spring-operated eject pin and trigger. The eject pin is cycled through cocked and un-cocked states by actuation of a cocking pin and trigger. At the end of the barrel assembly is a soft rubber collet configured to temporarily retain a pill of different shapes and volumes. The collet has an aperture through which the eject pin in its un-cocked state mechanically communicates at its tip with the inner area of the collet.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: March 5, 2019
    Inventor: Edgar C. Cohen, Jr.
  • Patent number: 10195053
    Abstract: The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectably detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area. In one embodiment, the integrated fusion cage is an expandable integrated fusion cage.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: February 5, 2019
    Assignee: SPINAL SURGICAL STRATEGIES, LLC
    Inventors: Jeffrey B. Kleiner, Edward John Grimberg
  • Patent number: 10136978
    Abstract: Dosing apparatus comprising a cartridge (11), the cartridge having: •a body (13) with a cavity holding at least one product to be dosed, •a nozzle (17) which is in communication with the cavity and which is configured for channelling the product to an orifice of an animal, and •a recess (21) which is adapted to, or actually does, receive and provide a cover for the nozzle of an identical or similar cartridge.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: November 27, 2018
    Assignee: Imaginus Limited
    Inventors: Paul Fleming Buckley, Robert William Lachlan Holmes, Malcom Norman Lynd
  • Patent number: 10118024
    Abstract: An insufflation pump includes a pump body having a first end and a second end. The pump body includes a syringe mechanism at the first end and an actuation mechanism at the second end. The syringe mechanism includes a plunger. The plunger of the syringe mechanism and the actuation mechanism are linked by a toggle assembly facilitating transfer of power from the actuation mechanism to the syringe mechanism.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: November 6, 2018
    Inventor: Stuart H. Miller
  • Patent number: 9566141
    Abstract: The invention includes a device for inserting a medicament within a body cavity of a mammal, and a cartridge for containing the medicament within the device, where the cartridge includes a housing, a retractable chamber for containing medicament disposed within the housing, and a substantially stationary member disposed within the barrel of the retractable chamber, where upon activation of the device, the retractable chamber is retracted about the substantially stationary member, thereby depositing medicament within the body cavity.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: February 14, 2017
    Assignee: Orapharma, Inc.
    Inventors: Zhangwen Wu, Michael J. Rello, James F. Hooper, James R. Lawter
  • Patent number: 9456830
    Abstract: A bone graft delivery system can include an elongate tube, a handle having a trigger, and a tip. The trigger is actuated to deliver bone graft material through the tube. The tip has one or more openings to deliver the bone graft material to a desired location and includes a surface suitable to act as a rasp for decorticating bone. A method for delivering bone graft material to a desired surgical location includes providing a bone graft delivery device, positioning the device adjacent the surgical location, decorticating bone, and delivering bone graft material to the surgical location.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: October 4, 2016
    Assignee: Surgical Device Exchange, LLC
    Inventor: Travis Greenhalgh
  • Patent number: 9326873
    Abstract: A valve loading system is provided that uses a valve loader to transfer a valve or other medical device from a storage cartridge into a deployment catheter. The valve or other medical device can be implanted or positioned within a patient using the catheter after the valve or other medical device has been compressed and loaded into the catheter using the valve loader. The process then can be repeated by using the valve loading system to load or introduce another valve or other medical device into the catheter.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: May 3, 2016
    Assignee: SPIRATION, INC.
    Inventors: Martin Neal Adams, James Mark Kutsko, Desmond O'Connell
  • Patent number: 8986363
    Abstract: A delivery device for proximally releasing an expandable prosthesis and method of use thereof are described. The delivery device comprises an introducer sheath that is capable of distally advancing relative to the endoprosthesis to thereby expose the endoprosthesis from a proximal end thereof. The device is also capable of resheathing over the prosthesis in a proximal direction. The device comprises a drive pulley that can engage a particular gear set to axially move the introducer sheath and proximally release the prosthesis. The drive pulley can also engage another gear set to resheath the introducer sheath and recapture the prosthesis between the inner catheter and the introducer sheath. A directional switch enables the device to operate between the two modes.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: March 24, 2015
    Assignee: Cook Medical Technologies LLC
    Inventors: Vincent McHugo, Donagh O'Sullivan
  • Patent number: 8968235
    Abstract: The bioinjection device has a housing including a pistol grip and an elongated barrel. A trigger is pivotally mounted to the housing. A plunger and needle are slidable between a first position in which the plunger and needle are slidably disposed in the barrel and a second position in which the plunger and needle extend from an opening in the end of the barrel. A retaining member is disposed about the opening at the end of the barrel. A spring-biased actuation mechanism connects the trigger with the plunger and needle. A membranous cartridge containing bone morphogenic protein, antibiotics, and/or other medication is loaded into the retaining member. A surgeon can inject the cartridge into a bone fracture or degenerative bone tissue during surgery to deliver the medicament directly to the affected site.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: March 3, 2015
    Inventors: Clifford T. Solomon, Theodore C. Solomon
  • Patent number: 8858593
    Abstract: An emergency medical device and method is provided for treatment of open wounds by enhancing clotting and arresting hemorrhaging, particularly in the area of the neck, abdomen, chest or groin. The devices includes an elongated delivery tube for insertion into a wound cavity and subsequent delivery of a space filling, sponge-like mass containing a polymerizable liquid sealant that polymerizes upon contact with body fluids after which the delivery tube is removed.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: October 14, 2014
    Assignee: Charles W. Kerber, M.D., Inc.
    Inventor: Charles W. Kerber
  • Patent number: 8668676
    Abstract: Apparatus and methods for implanting ocular implants in eyes are provided which include a bent cannula having a lumen extending therethrough, the lumen having a length and a diameter and being configured to receive an ocular implant. The ocular implant is made up of a plurality of substantially uniformly sized particles, preferably a plurality of uniformly sized microspheres, arranged in a one-by-one array along the length of the lumen. The apparatus further comprises a mechanism for delivering the implant through the distal end of the lumen and into the eye, preferably without the use of a liquid or gel carrier medium located in the lumen along with the implant.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: March 11, 2014
    Assignee: Allergan, Inc.
    Inventor: James N. Chang
  • Patent number: 8545377
    Abstract: A magazine for chain components of a chain with radiation sources comprises a housing as well as a first means for receiving chain components that is mounted in a pivotal manner in the housing and has recesses for receiving the chain components, a tension spring for driving the means for receiving the chain components, a sprocket being coupled in a pivotal manner to the means for receiving the chain components and being mounted in a pivotal position in the housing, and an ejector for ejection of the radiation sources. Furthermore, the magazine comprises an ejection lever which is mounted in a pivotal manner in the housing, whereby, in a first position, the ejection lever engages the sprocket, and in a second position it blocks the ejector.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: October 1, 2013
    Assignee: Eckert & Ziegler Bebig GmbH
    Inventors: Axel Hentrich, Christoph Lederer
  • Patent number: 8523825
    Abstract: A dispenser device comprising a pistol housing, a needle direction control mechanism, a boost mechanism, a quantification control mechanism, and a combination of the pistol housing, the needle direction control mechanism, the boost mechanism, and a syringe positioning mechanism or a holding ring embodies the present invention with features and advantages shown as follows, (1) Uniform injection of agents synchronously mixed by not less than two contents; (2) Mixed agents not exposed in air; (3) Uniform injection, high air tightness, injection direction controlled by easy turning, smooth and convenient operation, high powerful operation via shifts of a push rod driven by a pressed trigger, promoted yield rate, assembly easily constructed, reduced manufacture cost, and convenient maintenance.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: September 3, 2013
    Assignee: Dermato-Plastica-Beauty (DPB)
    Inventor: Tsai-Ming Lin
  • Patent number: 8419722
    Abstract: An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: April 16, 2013
    Assignee: Spinal Restoration, Inc.
    Inventors: Mark Richards, Brian D. Burkinshaw, Kevin Pauza, James B. Rogan, John Wheeler
  • Patent number: 8409184
    Abstract: The resorbable cryoprobe device and process is a novel approach for treating localized disease allowing for the precise combined application of freezing temperatures and cytotoxic or cryosensitizing agents within a self-contained matrix/package for optimized tissue destruction. The cryopellet is comprised of a list of components including a source of cryogen to produce the sub-zero temperatures, a porous matrix to contain the cytotoxic agent, cytotoxic agent, and a delivery packet. Data presented herein demonstrates the efficacy of this approach in destroying cancerous tissue. For example, the application of freezing temperatures to ?10° C. results in approximately 15% cell death, while exposure to cytotoxic agents such as TRAIL produces minimal cell death. The utilization of the cryopellet approach results in a synergistic effect yielding complete cell death at the same temperature.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: April 2, 2013
    Assignee: CPSI Holdings LLC
    Inventors: John M. Baust, John G. Baust, Anthony T. Robilotto, Kristi K. Snyder, Robert G. Van Buskirk
  • Patent number: 8403923
    Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: March 26, 2013
    Assignee: Spinal Restoration, Inc.
    Inventors: Steven I. Whitlock, Brian D. Burkinshaw, Kevin Pauza
  • Patent number: 8357147
    Abstract: A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc. The method includes inserting an introducer needle through the annulus fibrosus by puncturing the annulus fibrosus with the introducer needle, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition into the disc through the introducer needle directly or indirectly so that the in situ curable composition contacts a defect in the annulus fibrosus; and curing said material in situ.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: January 22, 2013
    Assignee: Spinal Restoration, Inc.
    Inventors: Brian D. Burkinshaw, John L. Wheeler, James B. Rogan, Steven I. Whitlock
  • Patent number: 8328753
    Abstract: The bioinjection device has a housing including a pistol grip and an elongated barrel. A trigger is pivotally mounted to the housing. A plunger and needle are slidable between a first position in which the plunger and needle are slidably disposed in the barrel and a second position in which the plunger and needle extend from an opening in the end of the barrel. A retaining member is disposed about the opening at the end of the barrel. A spring-biased actuation mechanism connects the trigger with the plunger and needle. A membranous cartridge containing bone morphogenic protein, antibiotics, and/or other medication is loaded into the retaining member. A surgeon can inject the cartridge into a bone fracture or degenerative bone tissue during surgery to deliver the medicament directly to the affected site.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: December 11, 2012
    Inventors: Clifford T. Solomon, Theodore C. Solomon
  • Patent number: 8062282
    Abstract: Methods and apparatus are provided for temporarily occluding a body lumen. A method in accordance with one or more embodiments of the invention includes introducing a tip of a catheter into the body lumen, the tip including a central longitudinal axis; expelling a thermosensitive polymer from the tip of the catheter into a portion of the body lumen, with at least a portion of the thermosensitive polymer being expelled from the tip in a direction generally radially outward from the central longitudinal axis to improve adherence of the thermosensitive polymer to a wall defining the body lumen; and at least partially withdrawing the tip from the body lumen and allowing the thermosensitive polymer to harden as it warms to body temperature to form a plug in the body lumen.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: November 22, 2011
    Assignee: Fossa Medical, Inc.
    Inventor: Gloria R. Kolb
  • Patent number: 8047407
    Abstract: A device for delivery of biologic materials, comprising: a cartridge having at least two cylinder bores for fluids to be delivered, wherein each cylinder includes an exit port for a fluid, a plunger within each cylinder for pushing the fluids out of the cylinder, a housing adapted to receive the cartridge, wherein the housing or cartridge includes an adaptor to receive and lock a manifold that operably connects to the exit ports of the cartridge, at least two toothed rams, wherein each toothed ram is at least partially within a cylinder bore, a trigger connected to the housing, wherein the trigger includes a toothed drive rack, a toothed wheel assembly that cooperates with the toothed drive rack and with the toothed rams, as well as methods of making the device, methods of using the device to treat discs, kits including the device.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: November 1, 2011
    Assignee: Spinal Restoration, Inc.
    Inventors: John L. Wheeler, Gary Whipple, A. David Boccuti, Thomas T. Washburn, Andrew Nicholas Gentile, J. Brent Ratz, John Spiridigliozzi
  • Patent number: 7824359
    Abstract: The bioinjection device has a housing including a pistol grip and an elongated barrel. A trigger is pivotally mounted to the housing. A plunger and needle are slidable between a first position in which the plunger and needle are slidably disposed in the barrel and a second position in which the plunger and needle extend from an opening in the end of the barrel. A retaining member is disposed about the opening at the end of the barrel. A spring-biased actuation mechanism connects the trigger with the plunger and needle. A membranous cartridge containing bone morphogenic protein, antibiotics, and/or other medication is loaded into the retaining member. A surgeon can inject the cartridge into a bone fracture or degenerative bone tissue during surgery to deliver the medicament directly to the affected site.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: November 2, 2010
    Inventors: Clifford T. Solomon, Theodore C. Solomon
  • Patent number: 7632251
    Abstract: The present invention relates to a volume-adjustable micro-injection device. The device includes a base structure having a syringe positioning structure and a grip, in which the syringe positioning structure can flexibly accommodate injection syringes with different volumes; a holding structure capable of flexibly adjusting an injection angle of syringe content for easier operation; a qualitative controller capable of accurately controlling injection volume; a pressure pushing structure to hold and push a plunger; an injection controller interlinked with the qualitative controller and the pressure pushing structure; and an eject structure facilitating simple operation and easy replacement of injection syringes.
    Type: Grant
    Filed: June 12, 2007
    Date of Patent: December 15, 2009
    Assignee: Dermato-Plastica Beauty (DPB) Co., Ltd.
    Inventors: Tsai-Ming Lin, Ping-Sen Liao
  • Publication number: 20080269671
    Abstract: The present invention relates to a volume-adjustable micro-injection device. The device includes a base structure having a syringe positioning structure and a grip, in which the syringe positioning structure can flexibly accommodate injection syringes with different volumes; a holding structure capable of flexibly adjusting an injection angle of syringe content for easier operation; a qualitative controller capable of accurately controlling injection volume; a pressure pushing structure to hold and push a plunger; an injection controller interlinked with the qualitative controller and the pressure pushing structure; and an eject structure facilitating simple operation and easy replacement of injection syringes.
    Type: Application
    Filed: June 12, 2007
    Publication date: October 30, 2008
    Applicant: Dermato-Plastica-Beauty (DPB) Co., Ltd.
    Inventors: Tsai-Ming Lin, Ping-Sen Liao
  • Publication number: 20040106892
    Abstract: An injection apparatus includes components that facilitate injection of relatively viscous materials into a patient. An injection apparatus may include a transition-bore needle apparatus, which has a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, in which the diameter of the proximal end is greater than the diameter of the distal end. An injection apparatus may include a hand-held injection facilitation apparatus, which may be coupled to a syringe. The hand-held injection facilitation apparatus can include a pivot arm and a body with a rod disposed within the body and coupled to the pivot arm. Movement of the pivot arm results in a proximal or distal movement of the rod within the body to effectively cause material to be expelled from the syringe. An injection apparatus may include a transition-bore needle apparatus and a hand-held injection facilitation apparatus in combination.
    Type: Application
    Filed: November 14, 2003
    Publication date: June 3, 2004
    Inventor: Corbett Stone
  • Patent number: 6721595
    Abstract: The present invention relates to percutaneous sorbefacients for electroporation consisting of monoterpene and being useful in elevating percutaneous absorbability of drugs, etc. By adding these percutaneous sorbefacients to compositions for electroporation, the percutaneous absorbability of drugs can be elevated.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: April 13, 2004
    Assignee: Pola Chemical Industries Inc.
    Inventors: Yoshihiro Tokudome, Koji Owaku, Kenichi Goto, Kenji Sugibayashi
  • Patent number: 6682471
    Abstract: An apparatus is described that efficiently resupplies radioactive seeds to a brachytherapy applicator. A seed-holding system includes a holder and a transfer device. The holder, which may be disposable, stores the radioactive seeds and the transfer device, which may be reusable, helps shield and dispense the seeds. The holder is coupled to the transfer device, and the apparatus is mated to an applicator. After seeds have been dispensed, the apparatus may be disconnected from the applicator and the empty holder may be ejected from the transfer device, and replaced with a full holder.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: January 27, 2004
    Assignee: Mentor Corporation
    Inventors: Martin T. Steele, Sr., Scott Henderson, Joseph Harms, Charles R. Pitman
  • Patent number: 6629960
    Abstract: A medical instrument includes a needle nozzle that accepts a needle cam. A needle hub assembly includes a needle hub and a needle cannula, and when registration ribs of the needle hub are fitted between respective registration ribs of the needle cam, the needle is thereby fitted onto the medical instrument.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: October 7, 2003
    Assignee: Integrated Implant Systems, LL.C.
    Inventor: Diego Fontayne
  • Patent number: 6616664
    Abstract: A clamp assembly for an external fixation system includes a first clamp member receiving a first elongated and a second clamp member receiving a second elongated member. The first clamp member includes a first fastener rotatably in a first direction to lock the first elongated member relative to the first clamp member. A second fastener connects the first and second clamp members. The second fastener is rotatable in the first direction to independently lock the second elongated member relative to the second clamp member. The first fastener is hollow and the second fastener passes through the first fastener.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: September 9, 2003
    Assignee: EBI L.P.
    Inventors: Stephen B. Walulik, Kirk J. Bailey
  • Publication number: 20030141268
    Abstract: The production of a protein free synthetic polyisoprene which has both low levels of chemical impurities and good physical properties has yet to be realized. It has now been envisioned that the use of neodymium catalyzed polyisoprene will offer the combined advantages of both a clean, as well as, high cis-1,4 polymer. Synthesis of polyisoprene rubber using a neodymium based catalyst system is described. Characterization of the material shows the absence of an ultra high molecular weight fraction and the presence of very high cis-1,4-microstructure. Gum stock and black filled compound studies comparing neodymium polyisoprene with natural rubber, titanium polyisoprene, and lithium polyisoprene have been performed. Results indicate that polyisoprene rubber synthesized using a neodymium catalyst. system (Nd—PI) has similar stress-strain and tear properties as synthetic titanium polyisoprene.
    Type: Application
    Filed: October 18, 2002
    Publication date: July 31, 2003
    Inventors: Michael Lester Kerns, Michael Joseph Rachita
  • Patent number: 6592508
    Abstract: A method and apparatus for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending a longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore and is selectively movable in the longitudinal direction relative the needle from a retracted position spaced apart from the needle to an extended position wherein the plunger is advanced through the needle bore to eject at least one of the seeds through the bore, out of the distal end of needle and into the target area. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: July 15, 2003
    Assignee: Integrated Implant Systems, LLC
    Inventors: Steven S. Ravins, Edward Kaplan
  • Patent number: RE49369
    Abstract: A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: January 17, 2023
    Assignee: SHL MEDICAL AG
    Inventor: Slobodan Stefanov