Means For Placing Solid Treating Material In Body Patents (Class 604/57)
- Solid ejected from body inserted conduit (Class 604/60)
- Eject means moved by force applied to trigger associated with pistol grip (Class 604/61)
- Solid units successively fed to conduit from supply means (e.g., magazine, etc.) (Class 604/62)
- Eject means driven by spring (Class 604/63)
- Solid loaded into injector through opening in side wall of plunger housing (Class 604/64)
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Patent number: 11577952Abstract: A cup holder assembly includes a plurality of contacts that are configured to contact a cup so that a majority of an opening into the cup is uncovered by the cup holder, and the plurality of contacts are connectable to one or more cup holder guide rods of an assembly that dispenses and mixes or blends beverages.Type: GrantFiled: October 1, 2019Date of Patent: February 14, 2023Assignee: MANITOWOC FOODSERVICE COMPANIES, LLCInventors: Kenneth L. Lundberg, Marc-Alexander Lange, Dennies Bergman, Joseph Knauss
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Patent number: 11501386Abstract: A system for physiologically informed account metrics. The system includes a computing device configured to receive from a remote device operated by a third party, an account inquiry. The computing device is further configured to identify a biological extraction related to a particular user. The computing device is further configured to calculate a user account profile utilizing the biological extraction wherein the user account profile contains at least an element of user behavior data and at least an element of user hazard data. The computing device is further configured to generate an account machine-learning model and determine a response to the account inquiry utilizing an account metric.Type: GrantFiled: February 4, 2020Date of Patent: November 15, 2022Assignee: KPN INNOVATIONS, LLC.Inventor: Kenneth Neumann
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Patent number: 11497526Abstract: A surgical device comprising a shaft comprised of a first end and a second end; a clamp configured to be locked or unlocked attached to the first end of the shaft; an actuator shaft that is removably coupled to the shaft and configured to open and close the clamp; and optionally an anchor.Type: GrantFiled: November 15, 2019Date of Patent: November 15, 2022Inventors: Todd Michael Ujifusa, Marek Andrzej Jaworski
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Patent number: 11351297Abstract: Certain embodiments of a medicinal applicator can comprise a base, a medicinal cream receiving port in the base, and a shaft extending along a conceptual shaft axis from the base and terminating at an applicator tip. There is at least one exit aperture located along a portion of the shaft. An unobstructed pathway is in communication with the receiving port and the exit aperture. A stop plate that extends essentially radially from the base delineating the base from the shaft. The shaft possesses a shaft outer shape defined by a shaped leading and trailing edge defining a narrow diameter proximal zone that extends along the shaft from the stop plate to a gradually increasing diameter transition zone that extends to a large diameter paddle zone, which terminates into a shaft distal end.Type: GrantFiled: July 19, 2021Date of Patent: June 7, 2022Inventors: Ryan Maaskamp, Armand Maaskamp
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Patent number: 11337705Abstract: An embolization device may include a fiber section having a plurality of polymeric electrospun fibers and, optionally, a contrast agent. An embolization device may further include a plurality of fiber sections, wherein each fiber section is separated by a linker. A method of deploying such an embolization device may include inserting the embolization device into a vessel. The method may further include applying an electrical current to one or more of the linkers, applying electrothermal heat to at least a portion of the device, or applying force to at least a portion of a delivery vehicle for the device. A method of manufacturing the device may include electrospinning a fiber section, and processing the fiber section by straining, twisting, heating, or shaping it.Type: GrantFiled: May 23, 2019Date of Patent: May 24, 2022Assignee: NANOFIBER SOLUTIONS, LLCInventors: Jed Johnson, Tyler Groehl, Devan Ohst
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Patent number: 11331499Abstract: A medical implant device (100) is disclosed that can protect and shield an implant (101) as the implant (101) moves through body tissue. The medical implant device (100) can comprise a main body portion (110) having a payload opening (111) to receive a payload (i.e., an implant). The medical implant device (100) can also comprise a tapered nose portion (120) at a front end (103a) of the medical implant device (100) extending from the main body portion (110) and configured to penetrate body tissue. In addition, the medical implant device (100) can comprise a payload coupling interface (130) configured to couple the implant (101) to the main body portion (110).Type: GrantFiled: July 28, 2017Date of Patent: May 17, 2022Assignee: University of Utah Research FoundationInventors: David Kluger, Gregory Clark, Douglas Hutchinson, David Page, Suzanne Wendelken
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Patent number: 11311615Abstract: Provided herein are vaccine compositions for example in a dry powder form for intranasal delivery, and their preparation methods. Also provided are methods of using vaccine compositions, for example in stimulating mucosal or systemic immune responses by delivering the vaccine compositions intranasally.Type: GrantFiled: September 16, 2016Date of Patent: April 26, 2022Assignee: SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.Inventor: Shunji Haruta
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Patent number: 11259834Abstract: A medical device for treating an aneurysm in a blood vessel includes a hollow shaft for insertion into the blood vessel, an exit port at a distal end of the shaft, a deflection element, and a position sensor. The hollow shaft encompasses a wire-insertion channel for leading a wire to be inserted into the aneurysm. The exit port is configured for exiting the wire from the wire-insertion channel and into the aneurysm. The deflection element is located adjacent to the exit port and configured to deflect the wire from the wire-insertion channel to the exit port. The position sensor, which is coupled to the distal end of the shaft, is configured to produce signals indicative of a position and orientation of the exit port in the blood vessel.Type: GrantFiled: October 24, 2019Date of Patent: March 1, 2022Assignee: Biosense Webster (Israel) Ltd.Inventor: Assaf Govari
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Patent number: 10898701Abstract: A device for the dispensing of liquids is disclosed. In an embodiment the device comprises a first hollow bulb coupled to a second hollow bulb, wherein the first hollow bulb is compressible; and a separator element disposed between the first hollow bulb and the second hollow bulb, wherein the separator element defines a passage; wherein the second hollow bulb defines an opening.Type: GrantFiled: April 12, 2018Date of Patent: January 26, 2021Assignee: AJB LLCInventor: John L. Boone
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Patent number: 10857039Abstract: A hemostatic device for treatment of a gunshot wound includes a barrel, which has a first end that is open, and a plunger. The barrel is arcuate adjacent to a second end to define a tip section. A clotting medium and a gauze are positioned in the barrel proximate to the tip section and between the clotting medium and the first end, respectively. A plurality of slits that is positioned in the tip section defines a plurality of petals, which comprise plastic and are resiliently deformable. The plunger, which has a head that is sealably positioned in the barrel adjacent to the first end, is configured to be pushed into the barrel to apply pressure to the gauze and the clotting medium so that the petals separate. The clotting medium and the gauze are sequentially expelled from the barrel into a wound to induce clotting and to pack the wound.Type: GrantFiled: October 3, 2018Date of Patent: December 8, 2020Inventor: H. Chandler Bartholomew
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Patent number: 10588664Abstract: According to embodiments of the present invention, a subcutaneous implant delivery apparatus is provided. The apparatus includes a receiving portion configured to receive a subcutaneous implantable device; and a stabilizing portion configured to cooperate with the receiving portion to hold the subcutaneous implantable device in a fixed position. The receiving portion and the stabilizing portion are movable relative to each other between a released configuration, wherein the receiving portion and the stabilizing portion are configured to move apart from each other to allow the receiving portion to be inserted under a skin layer, and a closed configuration, wherein the receiving portion and the stabilizing portion are configured to move toward each other to allow the subcutaneous implantable device to be held adjacent to the skin layer. According to further embodiments of the present invention, a method of delivering a subcutaneous implantable device for accessing a vascular site is also provided.Type: GrantFiled: December 28, 2015Date of Patent: March 17, 2020Assignee: Agency for Science, Technology and ResearchInventors: Soo Ghim Lim, Ruey Feng Peh, Yee Han Kuan, Yanling Toh
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Patent number: 9867622Abstract: A system and method of delivering and detaching an implant within a body of a patient is described. A tether connects an implant with a delivery device. The delivery device includes a heater through which the tether passes. The inner lumen of the delivery system pusher may accommodate the lead wires which connect to the heater.Type: GrantFiled: April 13, 2015Date of Patent: January 16, 2018Assignee: MicroVention, Inc.Inventor: Heath Bowman
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Patent number: 9788840Abstract: An intracorporeal space filling device and a delivery system and method for using the device is disclosed. The space filling device is preferably configured for percutaneous delivery from a peripheral conduit of a patient. The space filling device has an elongated tubular or interconnected bead structure which may have a transmutable material disposed within it. The transmutable material can be altered from a non-rigid state to a rigid state by the application of various types of energy or by other suitable means. The space filling device can be positioned by a delivery system and detached from the delivery system after desired positioning is achieved.Type: GrantFiled: December 17, 2014Date of Patent: October 17, 2017Inventor: Michael P. Marks
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Patent number: 9781944Abstract: A lollipop ball is formed to a lollipop ball engagement mechanism and the lollipop ball engagement mechanism extends outward from the lollipop ball to releasably engage a proximal end of a lollipop stick. Alternatively, a lollipop ball is formed to a lollipop ball engagement mechanism that defines a cavity inside the sphere of the lollipop ball and the proximal end of the lollipop stick releasably engages the cavity located in the interior of the lollipop. Alternatively, the lollipop itself can be formed to define the cavity such that no lollipop ball engagement mechanism is required to releasably engage the proximal end of the lollipop stick. The lollipop stick can also include one or more design elements.Type: GrantFiled: July 23, 2015Date of Patent: October 10, 2017Assignee: SUGAR FACTORY, LLCInventor: Steve Davidovici
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Patent number: 9603600Abstract: Systems and methods are provided for using an actuator to deploy an implant configured to close a tissue puncture or a natural opening in a body. The actuator includes a handle that is rotated in a first direction to deploy a first set of deployable wings of the implant, and that is rotated in a second, opposite direction to deploy a second set of deployable wings of the implant. A guide wire coupled between the implant and the actuator rotates and/or moves axially with the actuator to cause the wings to deploy. After each of the first and second rotation strokes, the handle is prevented from rotating beyond the first and second strokes, respectively. After the wings are deployed to engage tissue therebetween, the handle is operated to eject the implant from the actuator.Type: GrantFiled: November 19, 2014Date of Patent: March 28, 2017Inventors: James E. Coleman, Christy Cummins
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Patent number: 9180006Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a second loop-shaped support, which is configured to abut a second side of the heart valve opposite to said first side, whereby a portion of the valve tissue is trapped between the first and second supports. An outer boundary of the second support is greater than an outer boundary of the first support.Type: GrantFiled: February 27, 2006Date of Patent: November 10, 2015Assignee: Medtentia ABInventor: Olli Keränen
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Patent number: 9033912Abstract: A drug delivery device for delivering a drug pellet to a site beneath the skin of a patient is provided, the drug delivery device including a housing having a chamber configured to hold at least one drug pellet, the chamber having a loading end and a delivery end, the loading end of the chamber having an opening for receiving a plunger and a drug pellet and the delivery end having an opening for receiving the plunger and passage of the drug pellet. The housing includes at least one hole substantially perpendicular to the chamber and formed to at least partially intersect the chamber. A capture pin is provided configured to be receivable within the at least one hole.Type: GrantFiled: March 28, 2012Date of Patent: May 19, 2015Assignee: Warsaw Orthopedic, Inc.Inventor: William F. McKay
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Publication number: 20150119796Abstract: The present teachings provide thread attachment mechanisms each having an internal and an external threaded portion. The internal and external threaded portions are configured to engage with each other to form an attachment. The thread attachment mechanism in the present teachings further include an anti-lockup feature. The present teachings further provide a cardiac implant engaged with a delivery catheter devices through a thread attachment mechanism having an anti-lockup feature of the present teachings. In one embodiment, the anti-lockup feature prevents the implant from being overly tightened to the delivery catheter. In another embodiment, the anti-lockup feature allows the implant to be released from the delivery catheter in a predictable and controlled manlier. Another aspect of the present teachings provides methods of using a threaded attaching mechanism of the present teachings to deliver, deploy, and release a cardiac implant.Type: ApplicationFiled: October 26, 2014Publication date: April 30, 2015Applicant: DC Devices, Inc.Inventor: Matthew J. Finch
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Publication number: 20150100040Abstract: A medical material supply device which can percutaneously supply a material for nerve regeneration that promotes the regeneration of a nerve is insertable into a vessel and includes: a supply section configured to penetrate from an inner wall to an outer wall of the vessel at a predetermined position in the vessel, thereby being able to supply a material for nerve regeneration to the outer wall of the vessel; and an elongated body which is inserted into the vessel, in which the supply section is provided with a linear portion which is provided at the elongated body and is configured to penetrate from the inner wall to the outer wall of the vessel.Type: ApplicationFiled: October 8, 2014Publication date: April 9, 2015Inventors: Risato KOBAYASHI, Ichirou HIRAHARA
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Publication number: 20150080855Abstract: Devices, systems, and methods for localized drug delivery. In at least one embodiment of a method of localized drug delivery, the method comprises the steps of placing a resorbable device within a tube, introducing the tube within a mammalian body at or near a tissue and/or organ within the mammalian body, and anchoring the resorbable device to the tissue and/or organ. Devices and systems useful for performing such a method are also disclosed herein, wherein an exemplary device comprises at least one drug release portion having at least one drug to be released over time and a binder intermixed with the at least one drug, and at least one resorbable anchor portion coupled to the at least one drug release portion.Type: ApplicationFiled: September 17, 2013Publication date: March 19, 2015Applicant: DTherapeutics, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Publication number: 20150080659Abstract: Systems and methods provide intraluminal delivery of a bandage structure within a body lumen or hollow body organ, e.g., for treating an injured gastrointestinal tract or an esophageal hemorrhage in a non-invasive way using endoscopic visualization. The systems and methods can be sized and configured to apply a chitosan bandage structure within a body lumen or hollow body organ, to take advantage of the mucoadhesive, antimicrobial, hemostatic, and potential accelerated wound healing properties of the chitosan material.Type: ApplicationFiled: November 20, 2014Publication date: March 19, 2015Inventors: Kenton W. Gregory, Amanda Dayton (formerly Senrud)
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Patent number: 8979821Abstract: A biomaterial mass is inserted through a punctum into a canaliculus in the lacrimal outflow system with a syringe. The mass has an outer cross section that is less than the inner cross section of the canaliculus. The mass absorbs liquid to swell to form a lacrimal filler or sealing mechanism. The lacrimal filler has an external cross section that conforms to the internal cross section of the canaliculus and a soft outer surface relative to the surrounding tissues to prevent erosion of the canaliculus lining. The lacrimal filler forms an occlusion that prevents the outflow of liquid through the lacrimal outflow system to retain tears within the eye to maintain eye lubrication and wetness. The mass and syringe are provided in kit with a rubber stopper and, optionally, a punctal dilator, an injecting catheter, and an enzyme for dissolving or degrading the lacrimal filler at a later time.Type: GrantFiled: April 14, 2009Date of Patent: March 17, 2015Assignee: Fezza Family Properties, LLCInventor: John Fezza
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Patent number: 8911425Abstract: Electronic pill (1, 11) comprising at least one medicine reservoir (2, 12) with a solid powder or granulate medicine, a discharge opening (3, 13) and an actuator responsive to control circuitry for displacing medicine from the reservoir (2, 12) to the discharge opening (3, 13). The medicine comprises a dispersion of one or more active ingredients—e.g., solids in powder or granulate form—in an inert carrier matrix. Optionally, the active ingredients are dispersed using intestinal moisture absorbed into the pill via a semi-permeable wall section (14).Type: GrantFiled: July 3, 2009Date of Patent: December 16, 2014Assignee: Medimetrics Personalized Drug DeliveryInventors: Johan Frederik Dijksman, Anke Pierik, Jeff Shimizu, Hans Zou
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Patent number: 8888745Abstract: The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6) extending from the housing (3), and a handle (15) for grasping and maneuvering the applicator (1) and the cannula (6) during insertion of an implant (2). In accordance with the invention, the handle (15) extends above at least part of the length of the cannula (6). Such a handle facilitates insertion of the cannula and/or accurate positioning of the implant.Type: GrantFiled: January 20, 2006Date of Patent: November 18, 2014Assignee: Merck Sharp & Dohme B.V.Inventors: Iris Epkjen Hobo Van Der Graaf, Maurice Petrus Wilhelmus Tak, Juergen Schmidt, Hendricus Johannes Vertegaal
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Patent number: 8877233Abstract: Described are hemostasis devices useful for implantation in biopsy tracts, which device comprise highly compact, dried hemostatic sponge elements. Preferred devices also include compacted sponge matrices exhibiting high density and rigidity in combination with high volumetric expandability when wetted. Also described are methods for making and using such devices.Type: GrantFiled: June 28, 2002Date of Patent: November 4, 2014Assignee: Cook Biotech IncorporatedInventors: Joseph Obermiller, Michael C. Hiles
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Publication number: 20140303597Abstract: A device and method for administering a dose of particulate solid medication to a nursing age infant or child through a tube having one end held in a nursing nipple. The tube is held in a holder piece which also mounts the nipple aligned with the tube. The tube is resiliently bendable to hold the dose of medicine loaded therein prepatory to being released to pass down to said nipple. A child having the nipple in his or her mouth reflexively swallows the medicine passing out of the nipple.Type: ApplicationFiled: April 3, 2013Publication date: October 9, 2014Inventor: Tim Platt
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Patent number: 8855746Abstract: An endoscopic medical tool is endoscopically inserted into a body cavity in order to eject a member into the body cavity, and includes: a flexible sheath having an inner cavity; an elastically deformable stopper which is provided projecting out toward the inner cavity in a distal end portion of the sheath, and prevents the member which has been loaded inside the sheath from falling out of the sheath; and a pusher which is inserted into the sheath in a freely advancing and retracting manner, and which pushes out and ejects the member from the sheath. In the endoscopic medical tool, the stopper is formed in only a partial region of the inner cavity so that the stopper does not continuously formed over the entire circumference of the inner cavity.Type: GrantFiled: August 3, 2009Date of Patent: October 7, 2014Assignee: Olympus Medical Systems Corp.Inventor: Masaru Yuasa
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Publication number: 20140276636Abstract: Implantable drug delivery devices include a housing having a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure, and a drug contained in the drug reservoir lumen, wherein the first wall structure is impermeable to the drug and the second wall structure is permeable to the drug. Methods of providing controlled release of drug to a patient include deploying a drug delivery device in the patient releasing a drug from the drug reservoir lumen via diffusion through the second wall structure.Type: ApplicationFiled: March 17, 2014Publication date: September 18, 2014Applicant: TARIS BIOMEDICAL, INC.Inventors: Heejin Lee, Karen Daniel, Matthew Sansone
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Patent number: 8828050Abstract: Embodiments herein comprise a hemostatic composition comprising a plurality of liquid expandable articles capable of expanding upon contact with a liquid. A suitable composition comprises a plurality of liquid-expandable articles that may be mechanically uncoupled from one another and therefore may be capable of moving independently from one another. The plurality of liquid-expandable articles may comprise a compressed material capable of a high-degree of expansion upon liquid contact.Type: GrantFiled: May 4, 2010Date of Patent: September 9, 2014Assignee: Oregon Biomedical Engineering InstituteInventors: Kenton W. Gregory, Lauryn L. Baranowski, Arjun Kalyanpur, Seanna Vine, Grant Blackwell, Benjamin Margolis, Steven Dell
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Patent number: 8808156Abstract: The present invention relates to an applicator for delivering any of a plurality of predetermined radiation fields to a target in intraoperative radiotherapy. In a variant, the applicator comprises: a panel and at least one first pair of first and second grippers pivotally connected to the panel with each gripper having loop on an end. The loop is connected to an arm and the arm pivotally attached to the panel. The first and second grippers are configured to rotate in opposite directions to form an open position and come to a stopping point. The loops of the grippers are configured to slide under one another while rotating into a retracted configuration. Two end units are disposed on opposite ends of the panel, configured for being grasped by two independent graspers for fixing the applicator in position.Type: GrantFiled: May 5, 2011Date of Patent: August 19, 2014Inventors: Loren Godfrey, Jr., Loren Godfrey, Sr.
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Publication number: 20140221981Abstract: Intravesical devices are provided that are wholly deployable within the bladder of a patient in need of treatment and are well tolerated by the patient. The device may include an elastic body having a retention shape having (i) dimensions that provide intravesical mobility and that prevent voiding of the medical device through the urethra, and (ii) dimensions, buoyancy, or both, that exclude the medical device from entering the orifices of the ureters. The elastic body may exert a maximum acting force less than 1N when compressed to a shape with a maximum dimension in any dimension of 3 cm. The device may include a drug for controlled release within the bladder, for treatment of the bladder or a regional tissue. Methods of treatment are also provided that include selecting a patient in need of treatment in the bladder where tolerability of the treatment is a primary concern.Type: ApplicationFiled: March 25, 2014Publication date: August 7, 2014Applicant: TARIS Biomedical, Inc.Inventors: Michael J. Cima, Heejin Lee
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Patent number: 8790293Abstract: Disclosed herein is an injector device for delivering an implant, the device including a retracting element, a cannula needle, and a plunger. The device may comprise an latch that, when actuated by a user, causes the retracting element to move the cannula needle away from the delivery site, allowing the plunger to eject the implant into the site. The device may be configured for intraocular drug delivery.Type: GrantFiled: February 8, 2013Date of Patent: July 29, 2014Assignee: pSivida US, Inc.Inventors: Martin Nazzaro, Josh York, Ron LeBlanc
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Patent number: 8753308Abstract: Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.Type: GrantFiled: November 15, 2012Date of Patent: June 17, 2014Assignee: AcelRx Pharmaceuticals, Inc.Inventors: Pamela Palmer, Andrew Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Lawrence Hamel, William Kolosi, Sascha Retailleau
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Patent number: 8734430Abstract: The invention relates to an intraruminal sustained release capsule which is capable of delivering a sustained release dose of a first medicament to an animal, as well as either or both of a dump dose of a second medicament or mineral, and an exit dose of a third medicament or mineral. The capsule can have a dissolvable overcap molded from plasticized starch enabling a dump dose of medicament to be held between the overcap and one end of the capsule. A piston within the body of the capsule can be modified to enable it to accommodate an exit dose of medicament within its hollow interior which is aligned with an aperture at the end of the capsule which enables release of the medicaments to the rumen. After insertion of the capsule in the animal the overcap (if present) dissolves and separates from the capsule to release the dump dose of medicament. The sustained release medicament is then dispensed via the apertured end, followed by the release of the exit dose of medicament (if present).Type: GrantFiled: July 16, 2010Date of Patent: May 27, 2014Assignee: Merial LimitedInventor: Robert William Lachlan Holmes
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Patent number: 8721621Abstract: A method delivers an implantable device through the urethra and into the bladder. A deployment instrument is inserted into the urethra, the implantable device is inserted into the deployment instrument, and a stream of fluid is injected into the deployment instrument. The stream of fluid drives the implantable device from the deployment instrument into the bladder. The deployment instrument is removed from the urethra, leaving the implantable device wholly implanted in the bladder.Type: GrantFiled: September 10, 2010Date of Patent: May 13, 2014Assignee: TARIS Biomedical, Inc.Inventors: Jim Boyko, Grace Kim, Heejin Lee, Michael J. Cima, Jennie Kwo
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Patent number: 8715706Abstract: A device for drug delivery to an orifice of a subject, comprising a shell which is elastically stressed by an active pharmaceutical ingredient, said shell containing and being substantially impermeable to said active pharmaceutical ingredient, wherein said shell has at least one hole sized for in-vivo release of said active pharmaceutical ingredient as a result of elastic stressing.Type: GrantFiled: June 17, 2010Date of Patent: May 6, 2014Assignee: RDD Pharma, Ltd.Inventor: Nir Barak
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Patent number: 8715223Abstract: Drug depot delivery devices and methods are provided for delivering one or more drug depots in close proximity to the nerve of a patient with or without repositioning the cannula. The device includes an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot near the nerve.Type: GrantFiled: July 22, 2009Date of Patent: May 6, 2014Assignee: Warsaw Orthopedic, Inc.Inventor: William F. McKay
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Patent number: 8702677Abstract: Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.Type: GrantFiled: October 31, 2008Date of Patent: April 22, 2014Assignee: Warsaw Orthopedic, Inc.Inventors: Thomas A. Simonton, Sean M. Haddock, John Myers Zanella, William F. McKay
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Patent number: 8697044Abstract: The present invention discloses a cross-linked hyaluronic acid/collagen formulation which has improved composition for dermal filling and higher persistence than cross-linked collagen or HA alone. Also disclosed are methods for preparing cross-linked hyaluronic acid/collagen formulations and using such for augmenting soft tissues in mammals.Type: GrantFiled: October 7, 2008Date of Patent: April 15, 2014Assignee: Allergan, Inc.Inventors: Jacqueline A. Schroeder, Gregory S. Dapper, Kenneth C. Olson
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Publication number: 20140094767Abstract: A needle shell is inserted through skin with a needle insert within the needle shell occluding an insertion end of the needle shell. The needle insert is withdrawn from the needle shell and an implant tube is inserted into the needle shell and below the skin. An implant insertion rod is inserted into the needle shell to implant an implant below the skin.Type: ApplicationFiled: October 2, 2012Publication date: April 3, 2014Inventors: Robert F. Wallace, Matthew Q. Shaw
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Patent number: 8617097Abstract: An implantable drug-delivery sleeve for an elongate component of an implantable medical device. The sleeve includes a tubular substrate having a lumen configured to receive the elongate component so as to allow relative displacement of the substrate and the elongate component, wherein the substrate is shaped so as to be retained stationary at a desired position along the elongate component, and a drug releasably carried by the substrate.Type: GrantFiled: May 24, 2010Date of Patent: December 31, 2013Assignee: Cochlear LimitedInventors: Fysh Dadd, Jane Rapsey, Peter Gibson, Peter Schuller, Carrie Newbold
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Publication number: 20130338575Abstract: A closure piece for a powder syringe has a main body and a sealing element. The sealing element is disposed on the main body such that it rests in a sealing manner against a distal opening of a powder syringe when the closure piece is disposed in the closing position thereof on the powder syringe. A channel passes through the main body and the sealing element and has a proximal and a distal end. The closure piece includes a retaining element configured and/or disposed such that, prior to an activation of the powder syringe, any powder from a chamber of the powder syringe is at least substantially prevented from penetrating the channel when the closure piece is disposed in the closing position thereof on the powder syringe.Type: ApplicationFiled: February 23, 2012Publication date: December 19, 2013Applicant: VETTER PHARMA-FERTIGUNG GMBH & CO. KGInventors: Joachim Glocker, Tilman Roedle
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Patent number: 8603512Abstract: Methods and apparatus are provided for treating an injured or severed nerve pathway, wherein one or more microporous tubes are implanted into the nerve pathway to bridge the injured or severed region. A bioactive matrix including stem cells and nutrients is disposed within the microporous tube to facilitate growth of the stem cells and reestablishment of the sensory and motor conductive pathways through the injured or severed region. The microporous tube protects the bioactive matrix during development of the stem cells, and also retains the end regions in proper alignment during the nerve pathway regeneration.Type: GrantFiled: November 19, 2010Date of Patent: December 10, 2013Assignee: Nexeon Medsystems, Inc.Inventor: Mark C. Bates
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Patent number: 8579852Abstract: Methods and devices to process harvested skin tissue and to immediately reintroduce the ground tissue into the patient to repair a tissue defect are disclosed. A hand-held portable tissue grinder comprising a housing and a grinding element are disclosed. The tissue grinder is used for grinding skin and subcutaneous tissue and includes a sterile polymer housing having a first opening adapted to receive the skin and subcutaneous tissue. The tissue grinder also includes a sterile grinding element disposed substantially within the housing. The grinding element includes a plurality of cutting surfaces adapted to operably engage with the housing to provide ground tissue and further includes a handle mechanism coupled to the grinding element to move the grinding element with respect to the housing to grind the skin and subcutaneous tissue, wherein the ground tissue can be removed from the housing.Type: GrantFiled: February 19, 2010Date of Patent: November 12, 2013Inventor: Omeed Memar
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Patent number: 8574188Abstract: The invention relates to a novel drug delivery technology. More particularly the invention relates to a method of delivering at least one therapeutic compound or a formulation comprising the at least one therapeutic compound to a patient; to a throwaway or reusable device for delivering at least one therapeutic compound or a formulation comprising the at least one therapeutic compound to a patient in a manner as set out by the method; to a pioneer projectile for use in said method; to formulations for use in said method and to an injectate comprising a pioneer projectile and formulation. It also relates to a disposable component containing either a pioneer projectile or an injectate. The invention also relates to a throwaway or reusable device for delivering at least one therapeutic compound, or a formulation comprising the at least one therapeutic compound (hereafter drug) to a patient, and a method for administering a drug to a patient using said device.Type: GrantFiled: August 25, 2011Date of Patent: November 5, 2013Assignee: Glide Pharmaceutical Technologies LimitedInventors: David Stuart Potter, Charles David Ogilvy Potter
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Patent number: 8574189Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.Type: GrantFiled: March 9, 2012Date of Patent: November 5, 2013Assignee: AcelRx Pharmaceuticals, Inc.Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud, Pamela Palmer, Bradley Blackwood, Benjamin K. Yaffe
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Patent number: 8568374Abstract: An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. One or more retention elements are provided on the frame for retaining the frame within the uterus of a female mammal.Type: GrantFiled: April 29, 2010Date of Patent: October 29, 2013Assignee: Merck Sharp & Dohme B.V.Inventors: Wouter De Graaff, Harm Veenstra, Titia Martine Truce Mulders
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Publication number: 20130267931Abstract: Disclosed herein is an injector device for delivering an implant, the device including a retracting element, a cannula needle, and a plunger. The device may comprise an latch that, when actuated by a user, causes the retracting element to move the cannula needle away from the delivery site, allowing the plunger to eject the implant into the site. The device may be configured for intraocular drug delivery.Type: ApplicationFiled: February 8, 2013Publication date: October 10, 2013Applicant: PSIVIDA US, INC.Inventors: Martin Nazzaro, Josh York, Ron LeBlanc
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Publication number: 20130267928Abstract: Various embodiments provide an apparatus, system method for treating neurological conditions by delivering solid form medication to the ventricles or other areas of the brain. Particular embodiments provide an apparatus and method for treating epilepsy and other neurological conditions by delivering solid form medication to ventricles in the brain wherein the medication is contained in a diffusion chamber so as to allow the medication to dissolve in the cerebrospinal fluid of the brain and then diffuse out of the diffusion chamber to be delivered to the ventricles and brain tissue. In one or more embodiments, portions of apparatus have sufficient flexibility to conform to the shape of the ventricles of the brain when advanced into them and/or to not cause deformation of the ventricle sufficient to cause a significant physiologic effect.Type: ApplicationFiled: March 14, 2013Publication date: October 10, 2013Applicant: Incube, LLCInventors: Mir Imran, Phillip Morgan, Ben Tranchina, Paul Spher, Kyle Horlen
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Patent number: 8545377Abstract: A magazine for chain components of a chain with radiation sources comprises a housing as well as a first means for receiving chain components that is mounted in a pivotal manner in the housing and has recesses for receiving the chain components, a tension spring for driving the means for receiving the chain components, a sprocket being coupled in a pivotal manner to the means for receiving the chain components and being mounted in a pivotal position in the housing, and an ejector for ejection of the radiation sources. Furthermore, the magazine comprises an ejection lever which is mounted in a pivotal manner in the housing, whereby, in a first position, the ejection lever engages the sprocket, and in a second position it blocks the ejector.Type: GrantFiled: February 11, 2011Date of Patent: October 1, 2013Assignee: Eckert & Ziegler Bebig GmbHInventors: Axel Hentrich, Christoph Lederer