Material Flow Varying Means Controlled By Condition Responsive Sensor Patents (Class 604/65)
  • Patent number: 10688235
    Abstract: A method of performing a dialysis treatment includes using a pump and a dialysate supply line to transport peritoneal dialysis fluid, the supply line having a proximal end into which peritoneal dialysis fluid is supplied and from which spend dialysate is withdrawn, and a distal end which is connected to a patient's peritoneal access. The method further includes generating proximal and distal pressure signals using pressure detectors located at both the proximal and distal ends, respectively, of said supply line. During a drain cycle in which spent dialysate is pumped from the patient, the method includes, responsively to the proximal and distal pressure signals, detecting a characteristic of a pressure difference between the distal and proximal ends whose magnitude is determined by a predicted change in dialysate properties, and responsively to the characteristic, generating a signal indicating the change in dialysate properties.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: June 23, 2020
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
  • Patent number: 10653835
    Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: May 19, 2020
    Assignee: DexCom, Inc.
    Inventors: John Michael Dobbles, Apurv Ullas Kamath, Aarthi Mahalingam, James H. Brauker
  • Patent number: 10639661
    Abstract: A device for dispensing a fluid includes a fixed part to be worn by a user, a fluid connection including a terminal outlet, a needle coupled to the terminal outlet of the fluid connection for dispensing a fluid, and a replaceable part coupled to the fixed part via the fluid connection. The replaceable part includes a reservoir for containing the fluid to be dispensed, and a micro-pump coupled to the reservoir to send the fluid to the fixed part through the fluid connection. An actuator operates the micro-pump. The fixed part includes a pressure-sensor in proximity to the terminal outlet of the fluid connection and is associated with dispensing the fluid from the needle. An electronic control module controls operation of the micro-pump via the pressure-sensor.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: May 5, 2020
    Assignee: STMICROELECTRONICS S.R.L.
    Inventor: Fulvio Vittorio Fontana
  • Patent number: 10638931
    Abstract: A method and apparatus for metal implant contact detection through capacitive measurements is provided. Capacitive measurement is accomplished with a conductive wire/lead, for example a main needle. The measured capacitance as the main needle is moved through the skin and tissues increases, then jumps when the main needle makes contact with the metal implant, thus proving the metal implant exists and the location of the metal implant. The jump in capacitive measurement is detectable because the area of capacitance has gone from the main needle to the main needle plus the surface area of the metal implant surface area. The apparatus may also have a reference needle for taking reference needle capacitive measurements in the tissues surrounding the metal implant to increase the accuracy during use of the apparatus. A housing is provided for supporting the main and reference needles and supporting or housing apparatus electronics.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: May 5, 2020
    Assignee: Garwood Medical Devices, LLC
    Inventor: Brian R. Peterson
  • Patent number: 10639423
    Abstract: Provided is a drive unit for an auto-injector having a drive unit housing arranged for docking receipt of a syringe or of a cassette unit comprising a syringe movable from a rest position, in which a needle tip of the syringe is within the drive unit housing to a use position, in which the needle tip protrudes from a needle delivery aperture; and a drive arrangement including one or more electrically powered sources of axial drive; a first drive transfer element for advancing the syringe to said use position; and a second drive transfer element for moving a plunger into the barrel of the syringe to eject liquid contents thereof. The drive unit housing is provided with a skin sensor arrangement having an array of plural skin sensor electrodes located about the needle delivery aperture.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: May 5, 2020
    Assignee: UCB BIOPHARMA SPRL
    Inventors: Martin John McLoughlin, Michael James David Heald, Cameron Townley Charles, Dylan Sanders Garrett, Kevin Richard Lozeau
  • Patent number: 10617839
    Abstract: This disclosure relates to a portable oxygen concentrator system. The system includes a case containing a portable oxygen concentrator, a mask, and a button. The case is configured to be worn on a user's back. The mask is configured to deliver oxygen from the portable oxygen concentrator to the user. The button, when activated, is configured to cause the portable oxygen concentrator to deliver an increased flow of oxygen to the user for a period of time.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: April 14, 2020
    Inventor: Albert A. Lucio
  • Patent number: 10596324
    Abstract: There is provided a portable medical device for injecting insulin comprising a blood glucose meter, a first display that is capable of displaying the blood glucose content of a blood sample as determined by the blood glucose meter, means for injecting insulin in a patient comprising means for setting the amount of insulin to be injected comprising a second display that shows the amount of insulin to be injected characterized in that the device comprises a deactivation means that automatically switches off the first display.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: March 24, 2020
    Assignee: BRIGHTER AB
    Inventors: Truls Sjöstedt, Leif Hall
  • Patent number: 10555699
    Abstract: A method for use in detecting and monitoring effects experienced by a subject taking a first drug, drug A, and at least one other substance, substance B, the method comprising: (a) obtaining a plurality of measured values of a physiological characteristic of the subject over a time period; (b) comparing the measured values to a predefined signature, the drug A signature, associated with the first drug, and thereby calculating a measure, Adiff, of the difference between the measured values and the drug A signature; (c) comparing the measured values to a predefined signature, the substance B signature, associated with the at least one other substance, and thereby calculating a measure, Bdiff, of the difference between the measured values and the substance B signature; (d) comparing the measured values to a predefined signature, the DO signature, associated with a desired physiological state of the subject, and thereby calculating a measure, DOdiff, of the difference between the measured values and the DO signat
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: February 11, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Kiran Hamilton J. Dellimore, Murtaza Bulut, Ronaldus Maria Aarts
  • Patent number: 10546114
    Abstract: A method of authorizing a limited use intravascular device can include determining if the intravascular device is in communication with a clinical system; determining if the intravascular device is authorized for clinical operation without providing the clinical system access to intravascular device data stored on the intravascular device; and providing an authorization signal to the clinical system. An intravascular device can include a flexible elongate member including a sensing component at a distal portion and a connector at a proximal portion, the connector including: a memory component configured to store a parameter value; a processing component; and a charge storage component configured to power the memory component and/or the processing component; wherein the processing component is configured to determine if the flexible elongate member is authorized for clinical operation using the parameter value without providing the parameter value to a clinical system.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: January 28, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Timothy J. Kennedy, David Sprague, Jason Y. Sproul, Andreas Johansson, Francis Harrington, Derek Bruce Eldridge, Todd Bitner
  • Patent number: 10539078
    Abstract: Systems and methods for controlling a fluid based engineering system are disclosed. The systems and methods may include a model processor configured to generate a model output, the model processor including a set state module for setting dynamic states of the model processor, the dynamic states input to an open loop model based on a model operating mode. The model processor may further include an estimate state module configured to determine an estimated state of the model based on at least one of a prior state, current state derivatives, solver state errors, and synthesized parameters, the estimate state module using online linearization and gain calculation to determine estimator gain for determining the estimated state of the model.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: January 21, 2020
    Assignee: UNITED TECHNOLOGIES CORPORATION
    Inventors: Boris Karpman, Richard P. Meisner, Manuj Dhingra
  • Patent number: 10502649
    Abstract: Testing apparatus and method for testing compressed gas dispensing stations where a back pressure regulator is used to imitate filling of receiving vessels without the need for receiving vessels. A mass flow sensor measures the mass of compressed gas dispensed to the testing apparatus, and a controller calculates the pressure for the back pressure regulator to imitate filling of a receiving vessel.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: December 10, 2019
    Assignee: Air Products and Chemicals, Inc.
    Inventor: Joseph Perry Cohen
  • Patent number: 10342915
    Abstract: A sensor pad kit includes a sensor pad (701) which is flexible, and one surface of which is adhesive, having a sensor holding portion (702a) to which a sensor device (550) is to be attached, and at least two extended portions (718) extending toward an outer side from the sensor holding portion (702a) in a plan view, a fixing member (775) which fixes the sensor device to the sensor holding portion, and a peelable film (771) which is stuck to an adhesive surface of the sensor pad.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: July 9, 2019
    Assignee: Nemoto Kyorindo Co., Ltd.
    Inventors: Yumiko Fukikoshi, Shigeru Nemoto
  • Patent number: 10299903
    Abstract: Described herein is a dispenser for dispensing fluid that, integrated into one hand piece, comprises a variable volume chamber with a plunger disposed within the chamber and a chamber inlet and outlet. The inlet and outlet communicate directly with a common chamber volume and the plunger translates in a linear direction relative to the chamber along a common longitudinal axis to expel fluid from the chamber (expel stroke) and/or draw fluid into the chamber (drawing stroke). The plunger is linked to a controller, a power source and a motor that drives translation movement of the plunger. The dispenser described herein offers a variety of advantages over the art including accurate dosing without the user having the manually regulate the dose amount—the amount to be dosed is related to the volume of fluid in the chamber which can be pre-set or varied automatically using sensors and controllers.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: May 28, 2019
    Assignee: Te Pari Products Limited
    Inventors: Paul Fleming Buckley, Malcolm Lynd
  • Patent number: 10293099
    Abstract: A pump with a controller for adjusting head pressure using a pressure boost is provided. The pressure boost may be dynamically adjusted during a surgical procedure based on the device being used and inflow and/or outflow settings.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: May 21, 2019
    Assignee: Stryker Corporation
    Inventor: Brady L. Woolford
  • Patent number: 10286143
    Abstract: A pump is disclosed that comprises a primary control unit comprising a first processor and one or more modular pumping units removably docked to the primary control unit. Each modular pumping unit comprises a pumping mechanism and a second processor configured to control the pumping mechanism and communicate with the first processor. The modular pumping unit is configured to manipulate a portion of a fluid delivery set to pump a fluid. The first processor and the second processor are configured to exchange one or more operating parameters when the modular pumping unit is docked to the primary control unit. The modular pumping unit is configured to pump the fluid after being undocked.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: May 14, 2019
    Assignee: CareFusion 303, Inc.
    Inventor: Erik Barnes
  • Patent number: 10279105
    Abstract: Apparatuses and methods for delivery of medicaments such as insulin disclosed herein can increase the effectiveness of therapy by adjusting medicament delivery parameters to account for the loss of medicament absorption upon delivering medicament at a new insertion site. When a needle is inserted at a new site on a patient's body for delivery of medicament to that patient, a natural inflammatory response by the body to insertion of the needle causes the body to resist absorption of the delivered medicament. However, this medicament resistance decreases over time. Embodiments of the invention therefore adjust medicament delivery to deliver less medicament as time passes after an infusion set change causes medicament to be delivered at a new insertion site.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: May 7, 2019
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael Rosinko
  • Patent number: 10265469
    Abstract: The present invention relates to a compensation device for setting a flow rate of an infusion solution, a device for automatically controlling the flow rate of the infusion solution, and a method for controlling an optimal target flow rate using a flow rate coefficient of a flow rate controller, the compensation device adjusting a display scale of an infusion solution flow rate controller corresponding to a target flow rate on the basis of a one-time actually measured flow rate in setting the target flow rate by controlling an infusion solution flow rate controller of an infusion solution.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 23, 2019
    Inventors: Dooyong Lee, Poomin Park
  • Patent number: 10258774
    Abstract: Apparatus and methods are provided for managing delivery of fluid into a vessel. A balloon catheter with a 3-way valve is introduced into an occluded vessel. The 3-way valve permits fluid, such as a contrast dye, to be injected into the vessel lumen. The valve is also configured to permit the balloon portion of the catheter to be inflated by means of the same lumen used to inject the contrast dye into the vessel. Bloodstream pressure can also be measured before and after dilation to confirm the procedure was successful. This apparatus and method provides for a quick, safe, and reliable treatment of an occluded vessel, among other things and works with known and later developed systems.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: April 16, 2019
    Assignee: Teleflex Medical Incorporated
    Inventors: Jeffrey Vitullo, David T. Rowe, John Victor
  • Patent number: 10252020
    Abstract: A respiratory support ventilator apparatus mechanically supports the work of respiration of a patient. The ventilator apparatus is highly portable and optionally wearable so as to promote mobility and physical activity of the patient, and to improve the overall health of the patient. The respiratory support ventilator may monitor a physical activity level and overall health status of the patient, and process this information. The information is used to track efficacy of the ventilation therapy relative to activity level and quality of life, and or to titrate or optimize the ventilation parameters to improve, maintain or optimize the physical activity level and overall health status of the patient.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: April 9, 2019
    Assignee: Breathe Technologies, Inc.
    Inventors: Anthony D. Wondka, Angela King, Joseph Cipollone
  • Patent number: 10244965
    Abstract: A completely wireless capnography/drug delivery system is provided, with the drug delivery device reacting in relation to raw data transfers from the capnography device. Such a system utilizes the same capnography waveform generating algorithm within each component device (including an external connectivity base and a possible data center, as well) to receive raw data for comparison waveform results to ensure system functionality and to prevent outside data compromise or hacking. If an alert as to subject patient capnography waveform results initially at the capnography device, the other system component devices are alerted and such raw data is then transferred for such mirror capnography waveform generation at each location. Such a system thus allows for the drug delivery device to provide needed drug delivery operations directly, and wirelessly, in relation to such capnography waveform results, allowing the subject patient full mobility while monitored and treated.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: April 2, 2019
    Inventor: Jeffrey S. Gibson
  • Patent number: 10195352
    Abstract: A supplemental device for attachment to an injection device comprises an aligning arrangement for ensuring a predetermined positional relationship between the supplemental device and the injection device; and a securing arrangement for securing the supplemental device to the injection device.
    Type: Grant
    Filed: September 17, 2016
    Date of Patent: February 5, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Andre Baran, Kay Behrendt, Martin Haupt
  • Patent number: 10188840
    Abstract: Computerized oral prescription administration (COPA) devices, systems, and methods are provided. In one embodiment, a method of assembling a substance dispensing device includes forming a mouthpiece including a recess customized to match with an intended user's unique dentition; coupling a sensing element to the recess of the mouthpiece, the sensing element configured to determine if the intended user's unique dentition is positioned within the recess of the mouthpiece; and coupling a substance dispensing unit to the mouthpiece, wherein the substance dispensing unit is in communication with the sensing element and configured to dispense a substance to the intended user in response to the sensing element determining that the intended user's unique dentition is positioned within the recess.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: January 29, 2019
    Assignee: Berkshire Biomedical, LLC
    Inventors: Thomas M. Rouse, Susan B. Owen, Christy Corey
  • Patent number: 10183107
    Abstract: A tube clamp for an extracorporeal circulator recognizes various abnormal situations of the tube clamp and notifies a user. The tube clamp has a lid sensor, a tube sensor, and a plunger sensor. In a case where any one of detection of the closure of a lid portion via the lid sensor, detection of the mounting of a tube via the tube sensor, and detection of the movement of a plunger via the plunger sensor is not obtained despite the fact that there is an instruction for blocking the tube, it is determined that the blocking is abnormal. In a case where the three states including the closed state, the mounting state, and the movement state are detected despite the fact that there is no instruction for blocking the tube, it is determined that the tube is erroneously blocked. Such abnormal situations are notified to a user via an alarm.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: January 22, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Tomoki Utsugida
  • Patent number: 10182750
    Abstract: An example continuous glucose monitor includes a printed circuit board (“PCB”) having first and second outer layers and an inner layer, the inner layer disposed between the first and second outer layers; a semiconductor package having four corner portions and a plurality of pins, the semiconductor package coupled to the first outer layer of the PCB via the plurality of pins; an electrical ground plane formed on the PCB and coupled to at least one pin at each of a first, second, and third of the four corner portions, and not coupled to any pins at a fourth corner portion; an electrical contact for a sensor wire formed on the second outer layer of the PCB; a sensor trace having a first portion disposed on the first outer layer, a second portion disposed on the inner layer, and a third portion disposed on the second outer layer, the sensor trace having a first end coupled to a first pin of the plurality of pins and a second end coupled to the electrical contact for the sensor wire, the first pin at the fourth co
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: January 22, 2019
    Assignee: VERILY LIFE SCIENCES LLC
    Inventors: Mandy Philippine, Scott Matula, Johan Vanderhaegen, Louis Jung, Nivi Arumugam
  • Patent number: 10173005
    Abstract: The invention relates to a drug delivery device for administering a drug, comprising: a body adapted to retain a cartridge containing a drug, at least one electrical unit (EU) and a port for electrically contacting the electrical unit (EU), an adapter for attaching an injection needle to the drug delivery device, a safety mechanism (S1 to S6) arranged to prevent access to the port while an injection needle is in fluid communication with the cartridge and arranged to prevent establishing a fluid communication between an injection needle and the cartridge while the port is accessible.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: January 8, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Paul Richard Draper, George Cave, Joseph Butler
  • Patent number: 10080498
    Abstract: A capnography device including a suitable sensor to measure carbon dioxide concentration for a target patient/user is provided. Such a device utilizes at least one microprocessor (MCU) to govern overall activation and communication between the capnograph and ultimately a data center. Such a component is provided with at least one RFID tag in order to charge device and transfer data via inductive coupling and to use as device ID for data routing purposes. The MCU may thus provide pre-programmed information to determine alert levels for a target patient/user, with the utilization, additionally of a data recordation device to capture all sensor results for such a target patient/user as well. If an alert occurs, the MCU transfers of all subsequent information from the sensors to the data center. Thus, the inventive device and system provides a real-time, reliable, wireless surveillance and notification platform that has been lacking in the industry.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: September 25, 2018
    Inventor: Jeffrey S. Gibson
  • Patent number: 10046568
    Abstract: A recording apparatus includes a recording head that ejects liquid onto a recording medium, a liquid accommodating portion that accommodates the liquid, a relay portion that is provided on a flow path of the liquid between the liquid accommodating portion and the recording head and relays the liquid, a tube that forms at least a part of the flow path of the liquid between the liquid accommodating portion and the relay portion and is attachable and detachable with respect to the relay portion, and a holding portion that holds the tube in a state of being detached from the relay portion.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: August 14, 2018
    Assignee: Seiko Epson Corporation
    Inventor: Masaki Shimomura
  • Patent number: 10034976
    Abstract: A fluid infusion device and related operating methods are disclosed. The fluid infusion device has a housing, a fluid pump mechanism having an inlet and an outlet, a first flow path in fluid communication with the inlet and at least partially defined by structure compatible with fluid cartridge modules containing medication fluid, a second flow path in fluid communication with the outlet and terminating at a subcutaneous conduit for a body, and a drive motor that actuates the pump mechanism. An exemplary operating method detects a first installation of a fluid cartridge module in the housing. The detecting occurs after the housing has been affixed to the body and after the subcutaneous conduit has been inserted into the body. In response to the detecting, the operating method initiates an automatic priming operation to prepare the device for delivery of the medication fluid to the body.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: July 31, 2018
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Pablo Vazquez, Hubert K. Yeung, Anthony C. Ng
  • Patent number: 10022499
    Abstract: Methods and system for providing diabetes management including automatic time acquisition protocol and expiration date detection are provided.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: July 17, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventor: John R. Galasso
  • Patent number: 10007759
    Abstract: Medical devices having restrictive access, and methods thereof are provided.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: June 26, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Christopher V. Reggiardo, Namvar Kiaie, James Thomson
  • Patent number: 9999721
    Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary infusion device includes a motor operable to deliver fluid to a body of a user, a first control module to enable input power for the motor and provide a dosage command for operating the motor, and a second control module coupled to the first control module to receive the dosage command and operate the motor using at least a portion of the input power based at least in part on the dosage command. One of the first control module and the second control module detects an anomalous condition, and in response, disables the input power to the motor, stores diagnostic information for the anomalous condition in its internal memory, and automatically resets thereafter.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: June 19, 2018
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Steve Chow, Alexander S. Campbell, Yongbo Wang, Thomas W. Collins, Linda I. Torres
  • Patent number: 9999717
    Abstract: A system for detecting whether a vascular access has been interrupted in an arrangement in which two catheters or needles are present in a blood vessel, fistula or graft. A fluid line leading to a pump is connected via a first connector to a first indwelling catheter, and a fluid line leading from a pump is connected via a second connector to a second indwelling catheter. Each connector is equipped with an electrode in contact with the lumen of the connector, the electrodes electrically connected to an electronic circuit that measures the impedance or conductivity of fluid between the first connector and second connectors via a fluid path through the blood vessel, fistula or graft. An electronic controller receives the impedance or conductivity data and processes the data to determine whether a vascular access disconnection has occurred.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: June 19, 2018
    Assignee: DEKA Products Limited Partnership
    Inventors: Dirk A. van der Merwe, Michael G. Norris, Michael A. Baker, Todd A. Ballantyne, Michael J. Wilt
  • Patent number: 9976551
    Abstract: A device for syringe characterization can include a syringe pump with a plunger driver, for a syringe configured to contain can a fluid, wherein the syringe includes a barrel and a plunger. The barrel and the plunger therewithin together define a central longitudinal axis of the syringe. The device can also include a barrel outer diameter sensor, and a linear position sensor in a substantially parallel orientation with the central longitudinal axis of the syringe when the syringe is installed in the syringe pump. At least one moveable marker can be in communication with the linear potentiometer, being capable of indicating a location along the linear potentiometer corresponding to a selected location on the barrel of the syringe when the syringe is installed in the syringe pump.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: May 22, 2018
    Assignee: Smiths Medical ASD, Inc.
    Inventor: Michael L. Blomquist
  • Patent number: 9937291
    Abstract: A piston pump is described for pumping a fluid. The pump includes at least one cylinder having a piston movable inside the cylinder along the longitudinal axis of the cylinder by a drive, each cylinder having at an end face a mounting flange having at least one cylinder opening, and a chamber having a volume that changes when the associated piston is moved in the cylinder. The piston pump has an inlet port for supplying and an outlet port for draining the fluid. A rotatable valve plate is arranged on the other side of the mounting flange. The mounting flange has at least one passage in the region of the inlet port and the outlet port, respectively, through which the fluid can flow between the inlet port and/or the outlet port and the other side of the mounting flange. The valve plate has fluid-transporting means by which, upon rotation of the valve plate at least one cylinder opening can be connected to a passage of the inlet and/or the outlet port.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: April 10, 2018
    Assignee: B. BRAUN MELSUNGEN AG
    Inventor: Dietmar Eberhard
  • Patent number: 9931469
    Abstract: An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: April 3, 2018
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Adam M. Shain, Rajesh Kumar, Anil Namboodiripad
  • Patent number: 9934540
    Abstract: A system for use with one or more sources of patient-affiliated data corresponding with a group of patients. The system may contain a plurality of patient interface devices for interfacing with the group of patients. Each patient interface device may store a database that includes information related to each patient of the group of patients. Each patient interface device may be operable to generate a patient-specific guidance data set that may be used by the patient interface device to interface with a patient of the group of patients. The plurality of patient interface devices may be communicatively coupled to patient-affiliated data and a therapy database via a patient interface device gateway. The patient-specific guidance data sets may be automatically updated.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: April 3, 2018
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Dennis I. Schneider, Dennis A. Tribble, Matthew A. Valentine
  • Patent number: 9915206
    Abstract: Systems and methods for controlling a fluid based engineering system are disclosed. The systems and methods may include a model processor for generating a model output, the model processor including a set state module for setting dynamic states of the model processor, the dynamic states input to an open loop model based on the model operating mode. The model processor may further include an estimate state module for determining an estimated state of the model based on a prior state model output and the current state model of the open loop model the estimate state module using online linearization and gain calculation to determine estimator gain for determining the estimated state of the model.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 13, 2018
    Assignee: UNITED TECHNOLOGIES CORPORATION
    Inventors: Boris Karpman, Richard P. Meisner, Manuj Dhingra
  • Patent number: 9913950
    Abstract: An improved medicant delivery system 100 is disclosed wherein the carrier for the medicant is a fluid that can be atomized or vaporized by exposure to heat. The system provides for repeatable dose of medicant, can be stored in any orientation, and/or has an ability to maximize energy efficiency.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: March 13, 2018
    Assignee: CHONG CORPORATION
    Inventors: Jack Goodman, William O'Neill, Alexander ChinHak Chong, William Bartkowski, Peter Joseph Kovach, Larry Gawain Linde, Randy Eugene Berg
  • Patent number: 9905721
    Abstract: To provide a leak detecting sensor capable of favorably detecting a leak of a chemical liquid regardless of orientation in fixing to a patient. The leak detecting sensor has a plurality of light-emitting elements 11 each emitting light to be applied to the patient, and a single light-receiving element receiving the light emitted by the plurality of light-emitting elements and reflected by the patient. The plurality of light-emitting elements are placed to surround the single light-receiving element.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: February 27, 2018
    Assignee: NEMOTO KYORINDO CO., LTD.
    Inventors: Young-Kwang Park, Takanobu Yagi, Seiichi Ono, Tomoyuki Kawabe, Tatsuya Ito
  • Patent number: 9895491
    Abstract: Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: February 20, 2018
    Assignee: Tandem Diabeters Care, Inc.
    Inventor: Don Ludolph
  • Patent number: 9867941
    Abstract: Provided is a drive unit for an auto-injector having a drive unit housing arranged for docking receipt of a syringe or of a cassette unit comprising a syringe movable from a rest position, in which a needle tip of the syringe is within the drive unit housing to a use position, in which the needle tip protrudes from a needle delivery aperture; and a drive arrangement including one or more electrically powered sources of axial drive; a first drive transfer element for advancing the syringe to said use position; and a second drive transfer element for moving a plunger into the barrel of the syringe to eject liquid contents thereof. The drive unit housing is provided with a skin sensor arrangement having an array of plural skin sensor electrodes located about the needle delivery aperture.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: January 16, 2018
    Assignee: UCB Biopharma SPRL
    Inventors: Martin John McLoughlin, Michael James David Heald, Cameron Townley Charles, Dylan Sanders Garrett, Kevin Richard Lozeau
  • Patent number: 9841014
    Abstract: An insulin pump data acquisition device & system including: an insulin pump data acquisition device for use with an insulin pump, the data acquisition device including a holster having a wall defining an interior volume and an exterior volume, the exterior volume being sized to removably secure the insulin pump; an environmental sensor operable to generate environmental data in response to environmental conditions; memory operably connected to the environmental sensor, the memory being operable to store the environmental data; a controller operably connected to the environmental sensor and the memory, the controller being operable to control reading of the environmental data from the environmental sensor and writing of the environmental data to the memory; and a battery operably connected to power the environmental sensor, the memory, and the controller. The environmental sensor, the memory, the controller, and the battery are disposed within the interior volume.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 12, 2017
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Darren Y. K. Yap, Carl A. Link, Vincent Ming Hai Chow, William Jackson Dannemann, Jennifer Marie Reitmajer
  • Patent number: 9827372
    Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: November 28, 2017
    Assignee: DexCom, Inc.
    Inventors: John Michael Dobbles, Apurv Ullas Kamath, Aarthi Mahalingam, James H. Brauker
  • Patent number: 9795738
    Abstract: An algorithm and method of making intelligent therapy recommendations for insulin pump parameters is described. The pump parameters include basal rates, carbohydrate-to-insulin ratios (CIR), and insulin sensitivity factors (ISF). A determination of whether a therapy recommendation should be made is based on comparing an updated recommended change with a threshold. The updated recommended change to the pump parameter is made based on a previous recommended change to the pump parameter and the difference between a current blood glucose value and a targeted blood glucose level. The algorithm and method confirms the therapy recommendation is within safety parameters before displaying the therapy recommendation.
    Type: Grant
    Filed: May 10, 2015
    Date of Patent: October 24, 2017
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Garry M. Steil, Antonios Panteleon
  • Patent number: 9782543
    Abstract: A monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device is presented in which a fastening member releasably attaches the monitoring device to an axially elongated housing of the drug delivery device, a sliding member is shiftable relative to the fastening member in an axial direction and being adapted to operably engage with at least one dose setting component of the drug delivery device to follow an axial displacement of the dose setting component relative to the housing component, a first sensor arrangement for detecting a rotation of the dose setting component relative to the fastening member, a second sensor arrangement for detecting an axial displacement of the sliding member relative to the fastening member, and a processing member coupled to the first and to the second sensor arrangements to process first and second signals obtainable from the first and from the second sensor arrangements for determining the size of a dose dispensed by the drug de
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: October 10, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Jasmin Groeschke, Alexander Allerdings, Jan-Peter Spengler, Christoph Dette, Matthias Scharf, Andreas Bode, Michael Schrack
  • Patent number: 9775697
    Abstract: Described herein is a dispenser for dispensing fluid that, integrated into one hand piece, comprises a variable volume chamber with a plunger disposed within the chamber and a chamber inlet and outlet. The inlet and outlet communicate directly with a common chamber volume and the plunger translates in a linear direction relative to the chamber along a common longitudinal axis to expel fluid from the chamber (expel stroke) and/or draw fluid into the chamber (drawing stroke). The plunger is linked to a controller, a power source and a motor that drives translation movement of the plunger. The dispenser described herein offers a variety of advantages over the art including accurate dosing without the user having to manually regulate the dose amount—the amount to be dosed is related to the volume of fluid in the chamber which can be pre-set or varied automatically using sensors and controllers.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: October 3, 2017
    Assignee: TE PARI PRODUCTS LIMITED
    Inventors: Paul Fleming Buckley, Malcolm Lynd
  • Patent number: 9757591
    Abstract: Methods and systems for monitoring an automated radiopharmaceutical infusion apparatus are disclosed. A user interface graphically representing infusion apparatus components may be presented on a display device. Multiple sensors may be arranged within an infusion apparatus to measure property information associated with infusion apparatus components, including fluid pathways. The property information may include radioactivity and flow information. The property information may be compared with expected results. If the property information does not match the expected results, a fault condition may be indicated on the display device. The user interface may provide information and/or functions to manage the fault conditions.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: September 12, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventor: James A. Agamaite
  • Patent number: 9724475
    Abstract: Various embodiments of a “smart” drug delivery pen are provided which include a drug delivery pen having an inertial sensor or accelerometer. A system is also provided that includes the smart drug pen in conjunction with a data management unit(s) DMU. Various exemplary methods for use of the pens and systems are also described and illustrated.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: August 8, 2017
    Assignee: LifeScan, Inc.
    Inventors: Peter Krulevitch, Ulrich Kraft, Robert Wilk, Zara Sieh, Mitch Zhao
  • Patent number: 9717849
    Abstract: Some embodiments of an infusion pump system may include an occlusion sensor that can be used to detect when an occlusion exists in the fluid path between the medicine reservoir and the infusion site on the user's skin. Such an occlusion may occur, for example, when the fluid flow line (e.g., a cannula, infusion set tubing, or the like) is kinked. If the medicine dispensation path to the user is occluded, the user may receive no dosage or a lower dosage of the medicine. As such, the occlusion sensor can be used to indicate when the fluid is flowing or not flowing, thereby permitting the infusion pump system to communicate an alarm to the user if an occlusion exists.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: August 1, 2017
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Amit Mhatre, Jian Yao Wu, Mitchell Wenger, Steven A. Friedman
  • Patent number: 9649431
    Abstract: An infusion management system includes an infusion management server configured for providing an order to an infusion device to administer an infusion and the infusion device. The infusion device may be configured for receiving the order, associating the order with a patient, and adjusting at least one setting according to the order. A method for administering an infusion, an interface for an infusion device and a computer program product are also disclosed.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: May 16, 2017
    Assignee: Ivenix, Inc.
    Inventors: George W. Gray, William C. McQuaid, Jesse E. Ambrosina