Sensor Responsive To Body Condition Patents (Class 604/66)
  • Patent number: 10803142
    Abstract: A system and method for personalized dosing of a pharmacologic agent include: executing, using a processing device, a plurality of dosing regimen program modules to determine a respective plurality of dose sets in response to receiving, from an input device, a target response value for a patient; and executing, using the processing device, a dosing selection algorithm module, following executing the plurality of dosing regimen program modules and in response to receiving from the input device a response profile and a monitoring frequency of the patient, to determine a recommended dose set computed as a combination of the plurality of dose sets weighted by degrees of matching computed using fuzzy sets and the response profile.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: October 13, 2020
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Adam E. Gaweda, Michael E. Brier, George R. Aronoff, Alfred A. Jacobs
  • Patent number: 10792424
    Abstract: A liquid medicine administration device for administration of a liquid medicine includes a liquid delivery unit; a control unit configured to control the liquid delivery unit; an activity detection unit; a storage unit configured to store data indicating an amount of the liquid medicine that has already been delivered into the living body; and a calculation unit configured to calculate a residual amount of the liquid medicine in the living body on the basis of (i) the data indicating the amount of the liquid medicine that has already been delivered by the liquid delivery unit into the living body, and (ii) the activity detected by the activity detection unit, and calculate a scheduled delivery amount of the liquid medicine to be administered into the living body on the basis of the residual amount of the liquid medicine.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: October 6, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Shohei Sasaki
  • Patent number: 10786621
    Abstract: A medical device system is disclosed. The medical device system includes a first medical device and a second medical device. A remote interface including a touch screen is also included. The remote interface is in wireless communication with the first medical device and the second medical device. The remote interface is configured to provide a user interface to the first medical device and the second medical device. The remote interface is configured to receive user input through a touch screen. Also, a charging device is included. The charging device is configured to receive at least the first medical device and the remote interface and the charging device is configured to recharge a first medical device battery and the charging device is configured to recharge an interface battery in the remote interface. The charging device is connected to a personal computer wherein the personal computer provides information to the remote interface.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: September 29, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, John M. Kerwin, Kevin A. Durand, Gregory R. Lanier, Jr., Larry B. Gray, Gregg W. Rivinius, Gerald M. Guay, Bob David Peret, Colin H. Murphy, David Blumberg, Jr.
  • Patent number: 10772550
    Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: September 15, 2020
    Assignee: Intuity Medical, Inc.
    Inventors: John Gregory Aceti, Sterling Eduard McBride, Richard Morgan Moroney, III, Christopher Carter Gregory, Peter John Zanzucchi
  • Patent number: 10776466
    Abstract: An infusion system to administer fluid is disclosed. The infusion system includes an infusion pump having a pump processor, a pump memory and a pump radio to enable bi-directional communication. The pump memory stores a plurality of fingerprint tokens and security conditions. The infusion system includes a controller with a processor, a controller memory and a controller radio to transmit and receive communication from the pump radio. The controller includes a fingerprint scanner and a graphical user interface (GUI) and controls to manipulate the GUI. The GUI and fingerprint scanner enable the controller to scan and determine tokens based on scanned fingerprints. Additionally, communication between the infusion pump and the controller establish relative proximity between the infusion pump and the controller such that when the relative proximity exceeds a threshold distance at least one of the plurality of security conditions is automatically matched.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: September 15, 2020
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Yongbo Wang, Bozhil Makaveev
  • Patent number: 10758329
    Abstract: A transmucosal delivery device includes a mouthpiece configured for receipt on a user's teeth, a permeable member coupled to the mouthpiece, a measurement module coupled to the mouthpiece for monitoring hydration of the user, and an excitation module coupled to the mouthpiece for inducing release of a hydrating substance from the permeable member based on the monitored hydration. The hydrating substance is delivered to the user through the user's oral mucosal tissue. Alternatively, a permeable member of a transmucosal delivery device houses an insulin solution to be delivered to the user through the user's oral mucosal tissue, and a measurement module coupled to the mouthpiece for monitoring blood glucose concentration of the user.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: September 1, 2020
    Inventor: Raymond L. Wright, III
  • Patent number: 10722650
    Abstract: The present disclosure relates to a system and method for determining a basal rate adjustment based on risk associated with a glucose state of a person with diabetes. A method may include detecting a glucose state of the person based on a received glucose measurement signal and determining a current risk metric associated with the detected glucose state. The method may include identifying a reference glucose state and a reference risk metric associated with the reference glucose state, and calculating an adjustment to a basal rate of a therapy delivery device based on the current risk metric associated with the detected glucose state and the reference risk metric associated with the reference glucose level.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: July 28, 2020
    Assignee: Roche Diabetes Care, Inc.
    Inventors: David L. Duke, Abhishek S. Soni
  • Patent number: 10722170
    Abstract: A method and/or system may be provided for determining a suggested change in a recommended therapy for a patient based, at least in part, on sensor measurements, and generating an alert to an attendant in a hospital environment upon detection of the suggested change. A method and/or system may also be provided to automatically determine a maximum interval to alert an attendant following receipt of a measurement at an operator interface. A method and/or system may also be provided to blood-glucose sensor calibration.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: July 28, 2020
    Assignee: Medtronic Minimed, Inc.
    Inventors: Martin Cantwell, H. Bud Clark, Garry M. Steil
  • Patent number: 10716896
    Abstract: Systems and methods for automatically delivering medication to a user. A sensor coupled to a user can collect information regarding the user. A controller can use the collected information to determine an amount of medication to provide the user. The controller can instruct a drug delivery device to dispense the medication to the user. The drug delivery device can be a wearable insulin pump that is directly coupled to the user. The controller can be part of or implemented in a cellphone. A user can be required to provide a confirmation input to allow a determined amount of insulin to be provided to the user based on detected glucose levels of the user. The sensor, controller, and drug delivery device can communicate wirelessly.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 21, 2020
    Assignee: INSULET CORPORATION
    Inventors: Jason O'Connor, Daniel Allis, David Nazzaro, John R. Bussiere, John D'Arco
  • Patent number: 10708102
    Abstract: A simultaneous wireless information and power transmission method includes: transmitting an energy transfer signal comprising a peak-to-average power ratio (PAPR) corresponding to information to be transmitted at a first side; measuring the PAPR by receiving the energy transfer signal at a second side; and recovering the information from the measured PAPR at the second side.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: July 7, 2020
    Assignee: Research & Business Foundation Sungkyunkwan University
    Inventors: Dong In Kim, Jong Ho Moon, Jong Jin Park, Kang Yoon Lee
  • Patent number: 10664569
    Abstract: A computer-implemented system and related method of reporting glucose information for a user of a diabetes management device are presented here. An embodiment of the method obtains input data for the user of the diabetes management device, and identifies a tracked glycemic response event. One or more recommended glycemic control parameters are calculated based on an analysis of the obtained input data. The glycemic control parameters are calculated to extend a time period during which the user remains within a target glucose range following the tracked glycemic response event. The method continues by generating an output message that includes at least some of the recommended glycemic control parameters, and delivering the generated output message to a user device operated by the user of the diabetes management device.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: May 26, 2020
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Chantal M. McMahon, Pratik Agrawal, Yuxiang Zhong, Boyi Jiang, Huzefa F. Neemuchwala, Amit J. Rushi
  • Patent number: 10653836
    Abstract: An integrated diabetes management (IDM) system includes a safety layer which, in one configuration has two components, one located between a glucose sensor and a controller and a second component located between a controller and a pump, to monitor various aspects of signals and modify those signals for compatibility and safety purposes. In one application, the safety layer receives output control signals from a controller and modifies those control signals as a function of an actual amount of insulin delivered to the user. The safety layer allows for an increased level of safety in the IDM system and permits development of separate hardware and software upgrades with the safety layer assuring that compatibility between components will continue.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: May 19, 2020
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Erwin S. Budiman
  • Patent number: 10631909
    Abstract: An ophthalmic surgical control apparatus is configured to be connectable to a piezo handpiece for emulsifying an eye lens. The control apparatus includes a frequency generator having a first and a second frequency module. The first frequency module generates a first oscillation signal having a first frequency lower than the ultrasonic resonant frequency of the piezo handpiece. The second frequency module generates a second oscillation signal having a second frequency greater than the ultrasonic resonant frequency of the piezo handpiece. A frequency generator control module controls the first and the second frequency modules.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: April 28, 2020
    Assignee: Carl Zeiss Meditec AG
    Inventor: Michael Eichler
  • Patent number: 10625022
    Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: April 21, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Christian Rehbein, Samuel Steel, Anthony Paul Morris, Matthew Meredith Jones, Robert Veasey, Richard James Vincent Avery, William Marsh
  • Patent number: 10617363
    Abstract: Methods and systems are disclosed analyzing a glucose level of a person having diabetes. The method, in at least one example, comprises receiving into a computing device a plurality of measured glucose values from a continuous glucose monitoring system coupled to a person having diabetes, analyzing the plurality of measured glucose values with a probability analysis tool on the computing device to determine a glucose threshold (gI0), and a boundary glucose value (g?) at a probability threshold where the person having diabetes requires at least a predetermined insulin dose, and comparing, with the computing device, the boundary glucose value (g?) to the glucose threshold (gI0), wherein if the boundary glucose value (g?) is greater than the glucose threshold (gI0) then the computing device performs an alert on a user interface.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: April 14, 2020
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Eric R Diebold, Alan Greenburg, David L Duke
  • Patent number: 10603498
    Abstract: A method or system for facilitating the determining and setting of stimulation parameters for programming an electrical stimulation system using closed loop programming is provided. For example, pulse generator feedback logic is executed by a processor to interface with control instructions of an implantable pulse generator by incorporating one or more machine learning engines to automatically generate a proposed set of stimulation parameter values that each affect a stimulation aspect of the implantable pulse generator, receive one or more clinical responses and automatically generate a revised set of values taking into account the received clinical responses, and repeating the automated receiving of a clinical response and adjusting the stimulation parameter values taking the clinical response into account, until or unless a stop condition is reach or the a therapeutic response is indicated within a designated tolerance.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: March 31, 2020
    Assignee: BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
    Inventors: David Blum, Sherry Lin, Hemant Bokil, Michael A. Moffitt
  • Patent number: 10595818
    Abstract: A medical system and method for density assessment utilizing ultrasound. The system includes a guidewire configured and dimensioned for insertion in the vessel of the patient, a sensor positioned at the distal portion of the elongated member and a connector connecting the elongated member to an indicator, the sensor determining the density and the indicator providing an indication of the determined density.
    Type: Grant
    Filed: February 19, 2017
    Date of Patent: March 24, 2020
    Assignee: Makaha Medical, LLC.
    Inventor: Marc-Alan Levine
  • Patent number: 10583251
    Abstract: Safety features are applied to an integrated insulin delivery system to enhance safety by controlling medication delivery including the automatic resumption of basal rate after a particular event, such as termination of a bolus, expiration of a time period, delayed resumption after the bolus has terminated, IOB comparison, and others. Other safety features include overriding a delivery control that may result in hypoglycemia, and terminating an extended bolus or temporary basal rate in view of a glucose signal indicating imminent carbohydrate deficiency. In another feature, an automatic resumption of a basal delivery rate is programmed into the delivery device to avoid the possibility of complete loss of delivery of insulin in the event that communication with the delivery device is disrupted.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: March 10, 2020
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Erwin S. Budiman, Gary A. Hayter, Nathan Crouther, Marc B. Taub, Wesley Scott Harper, Charles Wei
  • Patent number: 10569016
    Abstract: An infusion pump system providing therapy to a patient in a closed-loop or semi-closed loop mode can safely automatically revert to open-loop therapy. The system stores a default open-loop basal rate profile in memory. The system also continually tracks the insulin on board for the patient over a plurality of closed-loop therapy intervals. When an error or event occurs requiring reversion to open-loop therapy, the system automatically provides therapy according to the open-loop basal rate profile and the tracked insulin on board amount.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: February 25, 2020
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael J. Rosinko
  • Patent number: 10549036
    Abstract: A system and method for providing closed loop infusion formulation delivery which accurately calculates a delivery amount based on a sensed biological state by adjusting an algorithm's programmable control parameters. The algorithm calculates a delivery amount having proportional, derivative, and basal rate components. The control parameters may be adjusted in real time to compensate for changes in a sensed biological state that may result from daily events. Safety limits on the delivery amount may be included in the algorithm. The algorithm may be executed by a computing element within a process controller for controlling closed loop infusion formulation delivery. The biological state is sensed by a sensing device which provides a signal to the controller. The controller calculates an infusion formulation delivery amount based on the signal and sends commands to an infusion formulation delivery device which delivers an amount of infusion formulation determined by the commands.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: February 4, 2020
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Timothy J. Starkweather, Ronald J. Lebel, Rajiv Shah, Michael E. Miller
  • Patent number: 10496797
    Abstract: A method of controlling an insulin infusion device is presented here. The method can be implemented in a suitably configured electronic device, on an electronic storage medium, or the like. In accordance with certain embodiments, the method evaluates the operational integrity of a glucose sensor that measures sensor glucose values for a user of the insulin infusion device, and calculates a sensor integrity metric based on the evaluation. The calculated sensor integrity metric is used to adjust the aggressiveness of a closed-loop therapy algorithm that is used to control a closed-loop operating mode of the insulin infusion device. The insulin infusion device is operated in the closed-loop operating mode in accordance with the adjusted therapy setting.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: December 3, 2019
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Salman Monirabbasi, Benyamin Grosman
  • Patent number: 10463297
    Abstract: Medical devices and related patient management systems and event detection methods are provided. An exemplary method of detecting events pertaining to operation of a medical device, such as an infusion device, involves obtaining measurements indicative of a condition in a body of a patient, determining statistics for an analysis interval based on the measurements, and determining an event probability associated with the analysis interval based on historical event data associated with the patient. An event detection model associated with the patient is obtained and applied to the statistics and the event probability to identify occurrence of the event using the event detection model, and in response, an indication of the event associated with the analysis interval is provided, for example, by tagging or marking data in a database, displaying graphical indicia of the event, or the like.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: November 5, 2019
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Sinu Bessy Abraham, Chantal M. McMahon, Pratik Agrawal, Boyi Jiang, Yuxiang Zhong, Michael P. Stone, Huzefa F. Neemuchwala
  • Patent number: 10456524
    Abstract: Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: October 29, 2019
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Don Ludolph
  • Patent number: 10456086
    Abstract: A system, method and non-transient computer readable medium for predicting hypoglycemic risk in patients with diabetes following moderate exercise. A system may include a digital processor; and an exercise module configured to generate a hypoglycemia risk signal with a hypoglycemia prediction algorithm and to determine a hypoglycemia risk state with a classifier algorithm that classifies the hypoglycemia risk signal to identify an actionable hypoglycemia risk state based on a predefined threshold.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: October 29, 2019
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Marc D. Breton, Najib Ben-Brahim
  • Patent number: 10441718
    Abstract: An automated wearable device measure physiological signals, and when parameters which cause the wearer to be at risk are measured, the device delivers an antidote for a given medical condition. This prevents overdose or medical conditions from occurring.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: October 15, 2019
    Inventor: David Tchao
  • Patent number: 10426709
    Abstract: A feeding set for use with a peristaltic enteral feeding pump to deliver nutritional liquid fluid to a patient includes a container having nutritional liquid. A conduit assembly includes tubing placeable in fluid communication with the container and adapted for mounting on the enteral feeding pump. The tubing provides a fluid pathway for delivering the nutritional liquid from the container to a patient when the tubing is mounted on the enteral feeding pump. An identification member is mounted on the conduit assembly and has at least one characteristic of a nutritional liquid associated with the feeding set represented by the identification member. The identification member is positioned on the conduit assembly so as to permit automatic identification by the enteral feeding pump of the at least one characteristic of the nutritional liquid upon mounting the conduit assembly on the enteral feeding pump.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: October 1, 2019
    Assignee: KPR U.S., LLC
    Inventor: James Harr
  • Patent number: 10426382
    Abstract: The present technology relates to a detection device, a detection method, and a program capable of detecting a living body state of a human body easily and accurately. A contact lens type display device is provided with a tear detection unit 26 to collect tears on an eyeball and to analyze a constituent and detect affective information of a user. The detection result is sent from the contact lens type display device 11 to a mobile terminal SP and displayed on the mobile terminal SP. Consequently, the living body state can be detected on the basis of the constituent of the tears of the user, whereby the living body state of the user can be accurately detected. The present technology can be applied to a contact lens type display unit.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: October 1, 2019
    Assignee: SONY CORPORATION
    Inventors: Masakazu Yajima, Ken Hayakawa, Masanori Iwasaki, Tsukasa Yoshimura, Naoto Yamaguchi, Akira Tange
  • Patent number: 10405800
    Abstract: Disclosed are devices and methods for detecting activation of an electronic device, including a biomedical and biometric device. The electronic device can operate in a low-power mode until it is determined that the electronic device is in close proximity to or in contact with a body, and activated. The electronic device can include a first sensor including a first capacitance sensor, a second sensor, and a controller coupled to the first sensor and the second sensor. The controller can receive a first signal from the first sensor and determine that the electronic device is in close proximity to or in contact with a body based on the first signal, and receive a second signal from the second sensor and determine that the electronic device is activated based on one or both of the first signal and the second signal. The electronic device can transition from the low-power mode to an active mode in response to determining that the electronic device is activated.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: September 10, 2019
    Assignee: CAPSULE TECHNOLOGIES, INC.
    Inventors: Robert Ganton, Robert Ballam, Eugene Dantsker
  • Patent number: 10406286
    Abstract: Methods, system and devices for monitoring a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and automatic administration of a medication, detecting an impending administration of the medication level exceeding a predetermined threshold level, retrieving one or more signals associated with the monitored physiological condition, determining an accuracy indication of the retrieved one or more signals associated with the monitored physiological condition, and executing the administration of the medication level based on the accuracy indication are provided.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: September 10, 2019
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Gary Hayter
  • Patent number: 10398333
    Abstract: Devices, systems, and methods for controlling acquisition of a signal representing a physiological measurement are described herein. An example device comprises: an input for receiving the signal in digital form, wherein the signal has been acquired by means of at least one electrode without galvanic contact between the electrode and the living being and has been processed by circuitry for acquisition of the signal in analog domain to refine the signal before the signal is converted from analog to digital domain; an adaptation decision module, being configured to determine whether a measure of signal quality indicates that an adaptation of the circuitry for acquisition of the signal in analog domain is beneficial for the robustness of the system and/or the quality of the obtained signals; wherein the adaptation decision module, is arranged to output a control signal for controlling a parameter affecting amplifier saturation in processing of the signal.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: September 3, 2019
    Assignees: IMEC VZW, Katholieke Universiteit Leuven, KU LEUVEN R&D
    Inventors: Ivan Dario Castro Miller, Tom Torfs
  • Patent number: 10384010
    Abstract: Drug delivery device adapted to receive a drug-filled cartridge comprises a piston drive member for expelling a dose of drug from a loaded cartridge, a motor for driving the piston drive member, a rechargeable electric power source, an electrical connector allowing an external connector of a power source to be connected for recharging the power source, and a controller for controlling operation of the motor. The controller is adapted to detect a condition indicative of an external power source being connected to the electrical connector and subsequently disable the expelling assembly to thereby prevent that drug can be expelled from a loaded cartridge when an external power source has been connected to the electrical connector.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: August 20, 2019
    Assignee: Novo Nordisk A/S
    Inventors: Mikkel Schouenborg Grubbe, Mads Moeller, Carsten Schau Andersen, Thomas Soerensen, Jesper Hoeholt, Steffen Mews, Pete Brockmeier, Bjoern Gullak Larsen
  • Patent number: 10376630
    Abstract: Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: August 13, 2019
    Assignee: Bracco Diagnostics Inc.
    Inventors: Stephen E. Hidem, Aaron M. Fontaine, Janet L. Gelbach, Patrick M. McDonald, Kathryn M. Hunter, Rolf E. Swenson, Julius P. Zodda
  • Patent number: 10327709
    Abstract: A method to quantitatively predict a patient's serum lactate level, comprising measuring arterial blood pressure and heart rate from the patient, computing estimates of one or more cardiovascular parameters from the measured arterial blood pressure and heart rate, providing one or more classifiers that have been trained on a training data set including a reference set of arterial blood pressure, heart rate, and serum lactate levels and using the one or more classifiers to estimate the serum lactate level of the patient.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: June 25, 2019
    Assignees: Massachusetts Institute of Technology, The General Hospital Corporation
    Inventors: Thomas Heldt, Max H. Dunitz, George Cheeran Verghese, Andrew Tomas Reisner, Michael Filbin
  • Patent number: 10314974
    Abstract: A system and method for monitoring and delivering medication to a patient. The system includes a controller that has a control algorithm and a closed loop control that monitors the control algorithm. A sensor is in communication with the controller and monitors a medical condition. A rule based application in the controller receives data from the sensor and the closed loop control and compares the data to predetermined medical information to determine the risk of automation of therapy to the patient. A system monitor is also in communication with the controller to monitor system, remote system, and network activity and conditions. The controller then provides a predetermined risk threshold where below the predetermined risk threshold automated closed loop medication therapy is provided. If the predetermined risk threshold is met or exceeded, automated therapy adjustments may not occur and user/clinician intervention is requested.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: June 11, 2019
    Assignee: ICU Medical, Inc.
    Inventors: William Kenneth Day, Timothy L. Ruchti
  • Patent number: 10299739
    Abstract: A medical monitoring apparatus that monitors a status of a patient according to biological information of the patient includes a reliability evaluator 510 configured to obtain first biological information measured by a bedside monitor 200 and second biological information measured by a wearable sensor 300, and to evaluate a reliability of the second biological information according to a correlation between the first biological information and the second biological information, the first biological information and the second biological information belonging to an identical measurement item, and an alert determinator 600 configured to determine, using the first biological information and the second biological information, whether to issue an alert about an abnormality under a condition that depends on the reliability.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: May 28, 2019
    Assignee: Olympus Corporation
    Inventor: Nobuyuki Watanabe
  • Patent number: 10265516
    Abstract: The present disclosure describes a closely spaced array of penetrating electrodes. In some implementations, the electrodes of the array are spaced less than 50 ?m apart. The present disclosure also describes methods for manufacturing the closely spaced array of penetrating electrodes. In some implementations, each row of electrode of the array is manufactured in-plane and then coupled to other rows of electrodes to form an array.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: April 23, 2019
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Maurice S. Karpman, Andrew Meuller
  • Patent number: 10242159
    Abstract: A system for electronic patient care includes a network, a facility gateway, a device gateway application and a medical device. The facility gateway is configured to provide a publish-subscribe service for an application. The device gateway application is configured for execution by the facility gateway. The device gateway is configured to communicate via the network by providing a web service. The medical device is in operative communication with the network. The medical device is configured to communicate with the device gateway using the web service.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 26, 2019
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, John J. Biasi
  • Patent number: 10232113
    Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves determining a current amount of active fluid in the body of the user, determining a threshold amount of active fluid in the body of the user, and automatically altering operation of the infusion device to modify delivery of the fluid to the user based on a relationship between the current amount and the threshold amount.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: March 19, 2019
    Assignee: MEDTRONIC MINIMED, INC.
    Inventor: Cesar C. Palerm
  • Patent number: 10213539
    Abstract: Extracorporeal blood treatment apparatus (1) and methods as described herein involve control of blood line pressure utilizing a non-invasive pressure sensor (16).
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: February 26, 2019
    Assignee: Gambro Lundia AB
    Inventor: Paolo Rovatti
  • Patent number: 10188796
    Abstract: Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed into the controller. The infusion pump is configured to deliver insulin to a subject. The system provides the user with the ability to understand the effects of bolus insulin dosing upon their glucose levels. Specifically, the system provides a message that must include: (a) the trend of the user's glucose; (b) the recommended bolus; and (c) the actual bolus.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: January 29, 2019
    Assignee: LifeScan IP Holdings, LLC
    Inventors: Sweta Chovanda, Carlos O. Morales
  • Patent number: 10175162
    Abstract: This disclosure provides a workflow method and system associated with a paper-based sensor. Specifically, provided is a paper-based sensor workflow including printing of customized security sensing information and bio-reagents to produce a paper-based sensor, applying a test material, such as, but not limited to, blood, to the paper-based sensor, capturing an image of the paper-based sensor and performing a colorimetric process; and performing one or more analytics to produce results associated with the test material.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: January 8, 2019
    Assignee: Xerox Corporation
    Inventors: Nancy Y. Jia, Mandakini Kanungo, Wei Hong, Jing Zhou
  • Patent number: 10130765
    Abstract: Safety features are applied to an integrated insulin delivery system to enhance safety by controlling medication delivery including the automatic resumption of basal rate after a particular event, such as termination of a bolus, expiration of a time period, delayed resumption after the bolus has terminated, IOB comparison, and others. Other safety features include overriding a delivery control that may result in hypoglycemia, and terminating an extended bolus or temporary basal rate in view of a glucose signal indicating imminent carbohydrate deficiency. In another feature, an automatic resumption of a basal delivery rate is programmed into the delivery device to avoid the possibility of complete loss of delivery of insulin in the event that communication with the delivery device is disrupted.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: November 20, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Erwin S. Budiman, Gary A. Hayter, Nathan Crouther, Marc B. Taub, Wesley Scott Harper, Charles Wei
  • Patent number: 10117992
    Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: November 6, 2018
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Neha J. Parikh, Anirban Roy, Benyamin Grosman, Rebecca K. Gottlieb, Di Wu
  • Patent number: 10111761
    Abstract: A method, computer program product and computer system for mode selection of a prosthesis is provided. A processor of a wearable device receives a first input from a user. A processor of a wearable device determines the first input indicates a change to a mode of operation of the prosthesis. A processor of a wearable device sends a first command to the prosthesis to change the mode of operation of the prosthesis.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: October 30, 2018
    Assignee: International Business Machines Corporation
    Inventors: Eli M. Dow, Thomas D. Fitzsimmons, Joseph D. Harvey, Douglas E. Rohde
  • Patent number: 10088894
    Abstract: Embodiments of the invention generally relate to electronic devices capable of being implanted beneath the skin of a human user. The electronic devices include input devices for receiving input from a user, and output devices for output signals or information to a user. The electronic devices may optionally include one or more sensors, batteries, memory units, and processors. The electronic devices are protected by a protective packaging to reduce contact with bodily fluids and to mitigate physiological responses to the implanted devices.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: October 2, 2018
    Assignee: AUTODESK, INC.
    Inventors: Tovi Grossman, George Fitzmaurice, Anne Agur, Christian Holz
  • Patent number: 10010657
    Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: July 3, 2018
    Assignee: Boston Scientific Limited
    Inventors: Casey Torrance, Kate Walsh, Jared Salstrom, Scott Youmans, Edward I. Wulfman
  • Patent number: 10013595
    Abstract: An example electronic device (10) is provided. The electronic device (10) includes a screen (32), at least one electronic component (34) to detect at least one finger contacting the screen (32), and at least one processor (30) having a control unit (33). The control unit (33) processes data from the at least one electronic component (34) indicating that a first finger is contacting the screen (32), identifies a first finger image associated with the first finger, and correlates the contact of the first finger and the identified first finger image to a first action of a pointing input device to perform a first operation on the electronic device (10).
    Type: Grant
    Filed: November 28, 2013
    Date of Patent: July 3, 2018
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventor: Bharathi Sreenivas
  • Patent number: 10010686
    Abstract: A system for controlled delivery of medicinal fluid includes a fluid pathway assembly defining a fluid pathway and including means for calculating a first calculated fluid flow rate using gas laws. The fluid pathway assembly has an inline flow sensor element received within the fluid pathway movable in response to fluid flowing in the fluid pathway. A flow control device is removably attached to the fluid pathway assembly and has a sensor for sensing a position of the inline flow sensor element in the fluid pathway, the position of the inline flow sensor element being representative of a second calculated fluid flow rate. The fluid pathway assembly includes a variable flow resistor adjustable to regulate a rate of fluid flow in the fluid pathway assembly. A drive mechanism attached to the flow control device is operably coupled to the variable flow resistor when the flow control device is attached to the fluid pathway assembly.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: July 3, 2018
    Assignee: Ivenix, Inc.
    Inventors: Jesse E. Ambrosina, Benjamin G. Powers
  • Patent number: 9937286
    Abstract: A medical functional device, provided and designed for single use in a method for extracorporeally treating the blood of a patient, includes at least one process fluid circuit or sections thereof, each provided for receiving a process fluid, at least one first filter device arranged within the process fluid circuit or a section thereof and at least one second filter device arranged within the process fluid circuit or a section thereof. The present invention further relates to a process fluid and a medical treatment apparatus.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: April 10, 2018
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Matthias Brandl, Michael Herrenbauer, Wolfgang Wehmeyer
  • Patent number: 9907563
    Abstract: A fluid management system for use in a tissue resection procedure includes a controller. An inflow pump is operated by the controller and configured to provide fluid inflow through a flow path to a site in patient's body. An outflow pump is operated by the controller and configured to provide fluid outflow through a flow path from the site in patient's body. A motor driven resecting device may be provided for resecting tissue at the site. The controller is configured to actuate an inflow pump and an outflow pump in response to various signals and various algorithms are provided to provide malfunction warnings and assure safe operation.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: March 6, 2018
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Aaron Germain, Kyle Klein, Michael D. Walker, Robin Bek