Sensor Responsive To Body Condition Patents (Class 604/66)
  • Patent number: 11559693
    Abstract: Techniques for pairing an external device such as a clinician programmer (CP) to an implantable medical device (IMD) are disclosed, which involve use of a remote controller (RC) paired to the IMD. The RC is placed into a CP pairing mode, which acts differently depending on the type of IMD paired to the RC. If the IMD is RF based, the CP pairing mode places the IMD in a pairing mode, thus allowing the CP to connect directly with the IMD via a RF telemetry protocol. If the IMD is magnetic-induction based, the CP pairing mode causes the RC to advertise its presence to the CP, allowing the CP to connect to the RC via the RF telemetry protocol. Because the RC is also paired with the IMD via a magnetic induction telemetry protocol, the RC acts as a passthrough device to allow communications between the CP and the IMD.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: January 24, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Chirag Shah, Peter Yoo
  • Patent number: 11510811
    Abstract: A surgical system comprises a pressurized irrigation fluid source; an irrigation line fluidly coupled to the pressurized irrigation fluid source; a hand piece fluidly coupled to the irrigation line; and a controller for controlling the pressurized irrigation fluid source. The controller controls the pressurized irrigation fluid source based on an estimated flow value modified by a compensation factor.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: November 29, 2022
    Assignee: Alcon Inc.
    Inventors: Mikhail Boukhny, Raphael Gordon, Michael D. Morgan, Gary P. Sorensen
  • Patent number: 11455505
    Abstract: An injection vial and injection vial management system is disclosed, wherein the injection vial is filled with a liquid medicine and signally connected with a blockchain network. The injection vial includes a bottle body and a chipset disposed within the bottle body. The chipset includes an identification label and a blockchain module. The identification label records a manufacturing process, a logistic process and a use process. The blockchain module signal connects to the blockchain network in order to record the manufacturing process, logistic process and use process in the blockchain network.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: September 27, 2022
    Assignee: AI Bioelectronic Healthcare Co., Ltd.
    Inventor: Yen-Yi Ho
  • Patent number: 11379090
    Abstract: A firefighting monitor that has a first section, a second section joined to the first section by a first pivot connection, and a plurality of ball bearings positioned in the first pivot connection between a pair of bearing seats. Wherein, the bearing seats define an arc of contact with each of the plurality of ball bearings, the center of the arc of contact defining a tangent angled with respect to a flow axis defined by the first pivot connection.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: July 5, 2022
    Assignee: Elkhart Brass Manufacturing Company, Inc.
    Inventors: Eric N. Combs, Donald E. Sjolin, Frederic Einstein, Kevin McGuire, Lee R. Jones, John E. McLoughlin, Neocles G. Athanasiades, Kiam Meng Toh, Kyle A. Stoops
  • Patent number: 11376361
    Abstract: A system and method for monitoring and delivering medication to a patient includes a controller that has a control algorithm and a closed loop control that monitors the control algorithm. A sensor is in communication with the controller and monitors a medical condition. A rule base application in the controller receives data from the sensor and the closed loop control and compares the data to predetermined medical information to determine the risk of automation of therapy to the patient. The controller then provides a predetermined risk threshold where below the predetermined risk threshold automated closed loop medication therapy is provided. If the predetermined risk threshold is met or exceeded, automated therapy adjustments may not occur and user/clinician intervention is requested.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: July 5, 2022
    Assignee: ICU Medical, Inc.
    Inventors: Timothy L. Ruchti, Mohammad M. Khair
  • Patent number: 11369789
    Abstract: An embodiment relates to a transdermal drug delivery system comprising a patch comprising a) a cartridge comprising a drug; b) a bio-sensor and a non bio-sensor; c) an active delivery pad comprising an electrode for delivery of the drug into a tissue via iontophoresis; d) a power source of electrical energy connected to the electrode; e) a microcontroller configured to control a release of the drug wherein the patch is attached to the tissue via an adhesive pad, and optionally top of patch is covered with a sheet; wherein the bio-sensor is configured to detect a physiological parameter; wherein the non bio-sensor is configured with a software to control working of the patch.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: June 28, 2022
    Inventors: Ishaan Jain, Anjan S. Sesetty, Aditi Gubba, Om G. Desai
  • Patent number: 11357446
    Abstract: Devices, systems, and methods for delivering fluid therapy to a patient are disclosed herein. An exemplary method can comprise obtaining a urine output rate from a patient; causing a diuretic to be provided to the patient at a dosage rate, wherein the dosage rate is increased over a period of time such that the urine output rate increases to be above a predetermined threshold within the period of time; and causing a hydration fluid to be provided to the patient at a hydration rate. The hydration rate can be set based on the urine output rate to drive net fluid loss from the patient.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: June 14, 2022
    Assignee: Reprieve Cardiovascular, Inc.
    Inventors: Howard R. Levin, Jim Dillon, Andrew Halpert, Jeffrey Testani
  • Patent number: 11344529
    Abstract: The present invention relates to stable therapeutic compositions of pharmaceutical grade acids and pH buffering agents. The present invention also is directed to methods of treatment for mitochondrial disorders, metabolic conditions, diabetic conditions, and cardiovascular conditions, by administration of compositions of the present disclosure.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: May 31, 2022
    Assignee: REVEN IP HOLDCO LLC
    Inventors: Hendrik J. P. van Wyk, Peter B. Lange, James Ervin, Brian D. Denomme, Mariette L. van Wyk, Peter Pacult, Michael A. Volk
  • Patent number: 11338087
    Abstract: The present disclosure describes a closed-loop fluid resuscitation and/or cardiovascular drug administration system that uses continuous measurements and adaptive control architecture. The adaptive control architecture uses a function approximator to identify unknown dynamics and physiological parameters of a patient to compute appropriate infusion rates and to regulate the endpoint of resuscitation.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: May 24, 2022
    Assignee: Autonomous Healthcare, Inc.
    Inventor: Behnood Gholami
  • Patent number: 11302433
    Abstract: An apparatus comprising a pump, an input configured to receive information related to a user, a user interface, and a controller communicatively coupled to the pump, the input, and the user interface. The controller includes a timing module configured to initiate delivery of a drug in time and to adjust delivery according to the received information. Other devices, systems, and methods are disclosed.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: April 12, 2022
    Assignee: Tandem Diabetes Care, Inc.
    Inventors: Michael L. Blomquist, Kevin Kopp, Thomas Alan Savard
  • Patent number: 11266334
    Abstract: Disclosed are methods, apparatuses, etc. for calibrating glucose monitoring sensors and/or insulin delivery systems. In certain example embodiments, blood glucose reference samples may be correlated with sensor measurements with regard to a delay associated with the sensor measurements. In certain other example embodiments, a blood-glucose concentration in a patient may be determined based, at least in part, on one or more probability models, one or more functions for estimating blood-glucose concentrations, and/or blood glucose reference sample-sensor measurement pairs.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: March 8, 2022
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Anirban Roy, Barry Keenan, Michael Kremliovsky
  • Patent number: 11241542
    Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: February 8, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Christian Rehbein, Samuel Steel, Anthony Paul Morris, Matthew Meredith Jones, Robert Veasey, Richard James Vincent Avery, William Marsh
  • Patent number: 11241166
    Abstract: A body-mountable device is provided to facilitate communication, via in-body electrical signals transmitted via electrodes of the body-mountable device into fluid of the body, with a smart pill located in a gastrointestinal tract of a body to which the body-mountable device is mounted or with some other device located within the body. The body-mountable device can be a contact lens or other eye-mountable device such that the electrodes of the eye-mountable device can transmit in-body electrical signals via tear fluid. The body-mountable device could transmit a command to the smart pill to dispense a drug into the body. The smart pill could transmit, via in-body electrical signals, an indication of a detected property of the gastrointestinal tract to the body-mountable device. A latency of transmission of signals between the body-mountable device and the smart pill could be used to determine the location of the smart pill within the gastrointestinal tract.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: February 8, 2022
    Assignee: Verily Life Sciences, LLC
    Inventor: Shungneng Lee
  • Patent number: 11224366
    Abstract: The various embodiments disclosed herein are devices that deliver electrical stimulation and/or vibration stimulation to the surface of skin in proximity to insulin injections and/or glucose testing in order to decrease or eliminate the pain of these procedures.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: January 18, 2022
    Assignee: Innova Medical Design LLC
    Inventors: Timothy O'Malley, Rommel Vallero
  • Patent number: 11183287
    Abstract: A method, system and computer-readable medium are provided for determining compliance with patient care protocols, comprising an infusion pump providing infusion information pertaining to one or more drugs administered to a patient, the one or more drugs including sedatives and analgesics, and a processor communicably coupled to the infusion pump and configured to determine information regarding the one or more drugs being administered to the patient based on the infusion information by determining a baseline threshold for the one or more drugs being administered to the patient according to the actual dosage of the one or more drugs administered to the patient prior to a current time, determining a dosage amount of the one or more drugs currently being administered to the patient and comparing the dosage amount of the one or more drugs currently being administered to the baseline threshold to determine a deviation from the baseline threshold.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: November 23, 2021
    Assignee: CareFusion 303, Inc.
    Inventors: Tom Steinhauer, Terry Lee Blansfield, Leonard Mulkowsky, Andres Jesus Calderon, III
  • Patent number: 11164672
    Abstract: A system for electronic patient care includes a network, a facility gateway, a device gateway application and a medical device. The facility gateway is configured to provide a publish-subscribe service for an application. The device gateway application is configured for execution by the facility gateway. The device gateway is configured to communicate via the network by providing a web service. The medical device is in operative communication with the network. The medical device is configured to communicate with the device gateway using the web service.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: November 2, 2021
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, John J. Biasi
  • Patent number: 11160919
    Abstract: Mixing/administration systems and methods for preparing an agent for administration to an individual are disclosed. Caps may be included as part of the system, which may include compositions comprising at least one of a cleansing, antiseptic, antimicrobial, or disinfectant agent. The caps may additionally be included that may be used for hemostasis at an injection site. Packaging and/or the mixing/administration system within it may include a tracking mechanism for data tracking regarding many different aspects of the system, including aspects of manufacture and administration.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: November 2, 2021
    Assignee: Hyprotek, Inc.
    Inventor: Patrick O. Tennican
  • Patent number: 11156972
    Abstract: A system for light commercial building solutions (LCBS). Solutions and other systems may incorporate lightweight alerting service, auto-adjustment of gateway poll rates based on the needs of various consuming applications, detecting loss of space comfort control in a heating, ventilation and air conditioning (HVAC) system, HVAC capacity loss alerting using relative degree days and accumulated stage run time with operational equivalency checks, and HVAC alerting for loss of heat or cool capacity using delta temperature and dependent system properties. Also, incorporated may be triggering s subset of analytics by automatically inferring HVAC equipment details from controller configuration details, ensuring reliability of analytics by retaining logical continuity of HVAC equipment operational data even when controllers and other parts of the system are replaced, and an LCBS gateway with workflow and mechanisms to associate to a contractor account.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: October 26, 2021
    Assignee: Honeywell International Inc.
    Inventors: Paul Wacker, Gutha Stalin Sanghamitra, Suresh Vemuri
  • Patent number: 11151517
    Abstract: A method, system, and computer product for prompting a patient to take a medicine including collecting medicine prescription information associated with a patient, collecting medicine usage data associated with the patient, comparing the medicine usage data with the medicine prescription information, determining whether a medicine is taken by the patient as prescribed in the prescription information based on a comparison result of the medicine usage data and the prescription information, and generating one or more control signals to interrupt operations of one or more devices within an environment of the patient or environments of the patient's family member or caregivers, in response to determining that the medicine is not taken as prescribed.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: October 19, 2021
    Assignee: International Business Machines Corporation
    Inventors: Bradley C. Herrin, Morris S. Johnson, Jr., Jarett Stein, Xianjun Zhu
  • Patent number: 11116308
    Abstract: In some embodiments, an authorization server device receives a request for an activation token to activate a personal care device. The authorization server device determines an authorized usage amount, and generates an activation token based on the authorized usage amount to be transmitted to the personal care device. Activation of a personal care device may be authorized based on consumable products obtained for use with the personal care device. By limiting activation of the personal care device based on consumable products obtained for use with the personal care device, the technical problems in overuse of some consumable products (such as brush heads) or underuse of other consumable products (such as serums or cleansers) can be avoided, and maximum results from use of the personal care devices can be easier to obtain.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: September 14, 2021
    Assignee: L'Oreal
    Inventors: Zane Bowman Allen Miller, Geoffrey Deane
  • Patent number: 11107556
    Abstract: Systems and methods are provided for controlling dissemination of genomic data. One embodiment is a system that stores genomic data. The genomic data for each individual lists genetic variants determined to exist within that individual. The system receives an access request for a segment of genomic data for an individual, analyzes an authentication token within the request, authenticates the request as belonging to an account for a user based on the authentication token, and reviews authorization directives for the individual that indicate how predefined portions of genomic data are shared. The system also transmits the segment of genomic data in response to determining that the authorization directives permit the account to access the segment of genomic data, and prevents transmission of the segment of genomic data in response to determining that the authorization directives do not permit the account to access the segment of genomic data.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: August 31, 2021
    Assignee: Helix OpCo, LLC
    Inventors: Rani K. Powers, Christopher M. Glode, Ryan P. Trunck, Jennifer L. Lescallett
  • Patent number: 11083843
    Abstract: Methods, system and devices for monitoring a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and automatic administration of a medication, detecting an adverse condition associated with the monitored physiological condition or the medication administration deviating from a predetermined safety level of the closed loop control operation, and initiating a non-zero pre-programmed medication delivery rate are provided.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: August 10, 2021
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Gary Alan Hayter, Marc Barry Taub, Daniel Milfred Bernstein, Mark Kent Sloan
  • Patent number: 11085588
    Abstract: The invention relates to the balancing of fluid streams in a dialysis system. In particular the invention relates to a cassette for conveying a first and a second fluid stream in a dialysis system, wherein the first and the second fluid streams can be medical fluid streams such as for example dialysate streams or blood streams, wherein the cassette has a sensor as a device for balancing the first and the second fluid stream, and wherein the sensor has a first channel for the first fluid stream and a second channel for the second fluid stream. The invention further relates to a dialysis system, which is configured to accommodate at least one cassette which is configured as described above. Furthermore, the present invention relates to an arrangement by which two channels for the first and the second fluid streams are formed. In addition, the invention relates to a method for construction of the two channels or the arrangement.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: August 10, 2021
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Dejan Nikolic, Alexander Heide
  • Patent number: 11077091
    Abstract: The present invention relates to stable therapeutic compositions of pharmaceutical grade acids and pH buffering agents. The present invention also is directed to methods of treatment for mitochondrial disorders, metabolic conditions, diabetic conditions, and cardiovascular conditions, by administration of compositions of the present disclosure.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: August 3, 2021
    Assignee: Reven IP HoldCo LLC
    Inventors: James Ervin, Hendrik J. Van Wyk, Brian D. Denomme, Mariette L. Van Wyk, Peter Pacult, Michael A. Volk
  • Patent number: 11064946
    Abstract: Skin-mounted or epidermal devices and methods for monitoring biofluids are disclosed. The devices comprise a functional substrate that is mechanically and/or thermally matched to skin to provide durable adhesion for long-term wear. The functional substrates allow for the microfluidic transport of biofluids from the skin to one or more sensors that measure and/or detect biological parameters, such as rate of biofluid production, biofluid volume, and biomarker concentration. Sensors within the devices may be mechanical, electrical or chemical, with colorimetric indicators being observable by the naked eye or with a portable electronic device (e.g., a smartphone). By monitoring changes in an individual's health state over time, the disclosed devices may provide early indications of abnormal conditions.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: July 20, 2021
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: John A. Rogers, Ahyeon Koh, Daeshik Kang, YuHao Liu, Xian Huang
  • Patent number: 11033671
    Abstract: A system for detecting whether a vascular access has been interrupted in an arrangement in which two catheters or needles are present in a blood vessel, fistula or graft. A fluid line leading to a pump is connected via a first connector to a first indwelling catheter, and a fluid line leading from a pump is connected via a second connector to a second indwelling catheter. Each connector is equipped with an electrode in contact with the lumen of the connector, the electrodes electrically connected to an electronic circuit that measures the impedance or conductivity of fluid between the first connector and second connectors via a fluid path through the blood vessel, fistula or graft. An electronic controller receives the impedance or conductivity data and processes the data to determine whether a vascular access disconnection has occurred.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: June 15, 2021
    Assignee: DEKA Products Limited Partnership
    Inventors: Dirk A. van der Merwe, Michael G. Norris, Michael A. Baker, Todd A. Ballantyne, Michael J. Wilt
  • Patent number: 11033682
    Abstract: A method of insulin delivery, the method may include obtaining one or more blood glucose readings of a user, and, based on the blood glucose readings, generating a set of insulin delivery actions that may include delivery of a baseline basal rate or predefined variations of the baseline basal rate. The method may also include monitoring previous insulin delivery actions to the user to determine whether the previous insulin delivery actions include insulin beyond a threshold amount, where the previous insulin delivery actions may include delivery of the baseline basal rate or predefined variations of the baseline basal rate, and, based on the previous insulin delivery actions including insulin beyond the threshold amount, adjusting the set of insulin delivery actions.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: June 15, 2021
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Bryan Mazlish, Lane Desborough
  • Patent number: 10966609
    Abstract: An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: April 6, 2021
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Nelson Quintana, Antonio C. Llevares, John Michael Dobbles, Richard C. Yang, Michael Robert Mensinger
  • Patent number: 10922961
    Abstract: A remote control device may be used to wirelessly control functions of one or more dialysis machines, e.g. in a clinic environment and without requiring direct contact with the dialysis machines. Components of the remote control device may include control interfaces, e.g. buttons, for controlling and adjusting functions of a medical device, such as a dialysis machine, including, for example, volume control, blood pump control blood flow rate control and/or adjusting the level in the venous drip chamber, among other control features. Display of the remote control device may include one or more screens that may display information of one or more dialysis machines, patients undergoing dialysis treatment, and/or alarms or alerts of one or more of the dialysis machines. In an implementation, ultrasonic communication is used to wirelessly exchange information and commands between the remote control device and the one or more dialysis machines.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: February 16, 2021
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Sameera Anirudh Peesapati, David Yuds
  • Patent number: 10912524
    Abstract: A modular patient monitor has a docking station configured to accept a handheld monitor. The docking station has standalone patient monitoring functionality with respect to a first set of parameters. At least some of the first parameter set are displayed simultaneously on a full-sized screen integrated with the docking station. The handheld monitor also has standalone patient monitoring functionality with respect to a second set of parameters. At least some of the second set of parameters are displayed simultaneously on a handheld-sized screen integrated with the handheld monitor. The docking station has a port configured to accept the handheld monitor. While the handheld monitor is docket in the port, the docking station functionally combines the first set of parameters and the second set of parameters, and at least some of the combined first and second sets of parameters are displayed simultaneously on the full-sized screen.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: February 9, 2021
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, Paul Jansen, Massi Joe E. Kiani, Anand Sampath
  • Patent number: 10916896
    Abstract: A connector apparatus with a power isolation capability that is designed to transmit electricity from a power source to an electrical device is provided. The connector apparatus includes a housing with an input connector designed to electrically couple to the power source and an output connector designed to electrically couple to the electrical device, and a power isolation chip disposed in the housing and having an input electrically coupled to the input connector of the housing and an output electrically coupled to the output connector of the housing. The power isolation chip is designed to isolate its negative and positive output terminals from its negative and positive input terminals, thereby minimizing the generation of interference in the connector apparatus that transfers to the electrical device.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: February 9, 2021
    Inventor: Frank Dale Boxberger
  • Patent number: 10894125
    Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: January 19, 2021
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Neha J. Parikh, Anirban Roy, Benyamin Grosman, Rebecca K. Gottlieb, Di Wu
  • Patent number: 10888702
    Abstract: An interrogation system for a medical device includes a memory storing a diagnostic algorithm, a processor configured to run the diagnostic algorithm, and a communication module configured to facilitate data transfer between the interrogation system and the medical device. The diagnostic algorithm is configured to reach a diagnostic conclusion based on data from the medical device. The diagnostic algorithm is configured to iteratively interrogate the medical device for the data from the medical device until the diagnostic algorithm reaches the diagnostic conclusion, each iterative interrogation requesting additional data as compared to prior iterations. The communication module is configured to receive the additional data from the medical device in response to each iterative interrogation. The diagnostic algorithm is further configured to store an indication of the diagnostic conclusion within the memory.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: January 12, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jeffrey E. Stahmann, Howard D. Simms, Jr.
  • Patent number: 10881792
    Abstract: The embodiments described herein may relate to methods and systems for adjusting insulin delivery. Some methods and systems may be configured to adjust insulin delivery to personalize automated insulin delivery for a person with diabetes. Such personalization may include adjusting user specific dosage parameters in response to a user provided insulin delivery amount, including a user provided insulin delivery amount that varies from a recommended insulin delivery amount. Methods and systems may include locking out automated modification of a baseline basal rate of insulin for the user for the time period after a user provides an insulin delivery amount.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: January 5, 2021
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Bryan Mazlish, Lane Desborough, Ross Naylor
  • Patent number: 10874776
    Abstract: Various exemplary methods, systems, and devices for joint to pump elevation level user interfaces, autocalibration for joint elevation, and joint pressure estimation are provided. In general, an arthroscopic pump can be configured to estimate fluid pressure at a surgical site, e.g., at a joint, to provide an accurate indication of fluid pressure to users. In an exemplary embodiment, the fluid pressure estimation is based on a fluid pressure measurement at the pump that is adjusted at the pump, e.g., by a processor at the pump that executes instructions stored in a memory at the pump, using one or more control algorithms that adjust for one or more factors, such as pressure loss in tubing and sheath through which fluid flows between the pump and the surgical site and elevation difference between the pump and the surgical site.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: December 29, 2020
    Assignee: MEDOS INTERNATIONAL SARL
    Inventors: Oliver Dumas, Eduard Grinberg, Andre Francisco Guilherme, Michael Confoey, Jacob A. Marks
  • Patent number: 10864327
    Abstract: Methods, systems, and devices are disclosed for tracking delivery of medication. In one aspect, a medication delivery tracking device can interface with and be physically placed on a medication delivery pen device. The medication delivery tracking device can detect an occurrence of a delivery of a medication by the medication delivery pen device. In some implementations, the medication delivery tracking device can detect a dose amount of the medication delivered by the medication delivery pen device.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: December 15, 2020
    Assignee: Companion Medical, Inc.
    Inventors: Sean Saint, Jack Pryor, Arnold Holmquist
  • Patent number: 10864322
    Abstract: A portable infusion pump can communicate with glucose monitor, such as a continuous glucose monitor (CGM), to receive continuous feedback relating to a user's blood glucose level during insulin or other medicament therapy and can automatically deliver insulin to a user when the CGM data indicates a need for additional insulin. Due to potential unreliability in the correlation of the CGM data to the user's actual blood glucose level, risk mitigation can be employed to limit the amount of extra insulin that can be delivered by the pump in response to the CGM data.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: December 15, 2020
    Assignee: Tandem Diabetes Care, Inc.
    Inventors: Sean Saint, Michael Rosinko
  • Patent number: 10856809
    Abstract: An earpiece may include an earpiece housing, an intelligent control disposed within the earpiece housing, and a glucose sensor operatively connected to the intelligent control. The intelligent control may be configured to determine glucose levels associated with a user of the earpiece using the glucose sensor. The earpiece may further include a wireless transceiver disposed within the earpiece housing, the wireless transceiver operatively connected to the intelligent control. The glucose sensor may be a non-invasive glucose sensor such as a near infrared glucose sensor. The earpiece housing may be configured to position the glucose sensor against a wall of the external auditory canal.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: December 8, 2020
    Assignee: BRAGI GmbH
    Inventor: Peter Vincent Boesen
  • Patent number: 10842934
    Abstract: A glucose control system employs adaptation of a glucose target (set-point) control variable in controlling delivery of insulin to a subject to maintain euglycemia. The glucose target adapts based on trends in actual glucose level (e.g., measured blood glucose in the subject), and/or computed doses of a counter-regulatory agent such as glucagon. An adaptation region with upper and lower bounds for the glucose target may be imposed. Generally the disclosed techniques can provide for robust and safe glucose level control. Adaptation may be based on computed doses of a counter-regulatory agent whether or not such agent is actually delivered to the subject, and may be used for example to adjust operation in a bihormonal system during periods in which the counter-regulatory agent is not available for delivery.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: November 24, 2020
    Assignee: Trustees of Boston University
    Inventors: Firas H. El-Khatib, Edward R. Damiano, Steven J. Russell
  • Patent number: 10803142
    Abstract: A system and method for personalized dosing of a pharmacologic agent include: executing, using a processing device, a plurality of dosing regimen program modules to determine a respective plurality of dose sets in response to receiving, from an input device, a target response value for a patient; and executing, using the processing device, a dosing selection algorithm module, following executing the plurality of dosing regimen program modules and in response to receiving from the input device a response profile and a monitoring frequency of the patient, to determine a recommended dose set computed as a combination of the plurality of dose sets weighted by degrees of matching computed using fuzzy sets and the response profile.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: October 13, 2020
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Adam E. Gaweda, Michael E. Brier, George R. Aronoff, Alfred A. Jacobs
  • Patent number: 10792424
    Abstract: A liquid medicine administration device for administration of a liquid medicine includes a liquid delivery unit; a control unit configured to control the liquid delivery unit; an activity detection unit; a storage unit configured to store data indicating an amount of the liquid medicine that has already been delivered into the living body; and a calculation unit configured to calculate a residual amount of the liquid medicine in the living body on the basis of (i) the data indicating the amount of the liquid medicine that has already been delivered by the liquid delivery unit into the living body, and (ii) the activity detected by the activity detection unit, and calculate a scheduled delivery amount of the liquid medicine to be administered into the living body on the basis of the residual amount of the liquid medicine.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: October 6, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Shohei Sasaki
  • Patent number: 10786621
    Abstract: A medical device system is disclosed. The medical device system includes a first medical device and a second medical device. A remote interface including a touch screen is also included. The remote interface is in wireless communication with the first medical device and the second medical device. The remote interface is configured to provide a user interface to the first medical device and the second medical device. The remote interface is configured to receive user input through a touch screen. Also, a charging device is included. The charging device is configured to receive at least the first medical device and the remote interface and the charging device is configured to recharge a first medical device battery and the charging device is configured to recharge an interface battery in the remote interface. The charging device is connected to a personal computer wherein the personal computer provides information to the remote interface.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: September 29, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, John M. Kerwin, Kevin A. Durand, Gregory R. Lanier, Jr., Larry B. Gray, Gregg W. Rivinius, Gerald M. Guay, Bob David Peret, Colin H. Murphy, David Blumberg, Jr.
  • Patent number: 10776466
    Abstract: An infusion system to administer fluid is disclosed. The infusion system includes an infusion pump having a pump processor, a pump memory and a pump radio to enable bi-directional communication. The pump memory stores a plurality of fingerprint tokens and security conditions. The infusion system includes a controller with a processor, a controller memory and a controller radio to transmit and receive communication from the pump radio. The controller includes a fingerprint scanner and a graphical user interface (GUI) and controls to manipulate the GUI. The GUI and fingerprint scanner enable the controller to scan and determine tokens based on scanned fingerprints. Additionally, communication between the infusion pump and the controller establish relative proximity between the infusion pump and the controller such that when the relative proximity exceeds a threshold distance at least one of the plurality of security conditions is automatically matched.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: September 15, 2020
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Yongbo Wang, Bozhil Makaveev
  • Patent number: 10772550
    Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: September 15, 2020
    Assignee: Intuity Medical, Inc.
    Inventors: John Gregory Aceti, Sterling Eduard McBride, Richard Morgan Moroney, III, Christopher Carter Gregory, Peter John Zanzucchi
  • Patent number: 10758329
    Abstract: A transmucosal delivery device includes a mouthpiece configured for receipt on a user's teeth, a permeable member coupled to the mouthpiece, a measurement module coupled to the mouthpiece for monitoring hydration of the user, and an excitation module coupled to the mouthpiece for inducing release of a hydrating substance from the permeable member based on the monitored hydration. The hydrating substance is delivered to the user through the user's oral mucosal tissue. Alternatively, a permeable member of a transmucosal delivery device houses an insulin solution to be delivered to the user through the user's oral mucosal tissue, and a measurement module coupled to the mouthpiece for monitoring blood glucose concentration of the user.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: September 1, 2020
    Inventor: Raymond L. Wright, III
  • Patent number: 10722170
    Abstract: A method and/or system may be provided for determining a suggested change in a recommended therapy for a patient based, at least in part, on sensor measurements, and generating an alert to an attendant in a hospital environment upon detection of the suggested change. A method and/or system may also be provided to automatically determine a maximum interval to alert an attendant following receipt of a measurement at an operator interface. A method and/or system may also be provided to blood-glucose sensor calibration.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: July 28, 2020
    Assignee: Medtronic Minimed, Inc.
    Inventors: Martin Cantwell, H. Bud Clark, Garry M. Steil
  • Patent number: 10722650
    Abstract: The present disclosure relates to a system and method for determining a basal rate adjustment based on risk associated with a glucose state of a person with diabetes. A method may include detecting a glucose state of the person based on a received glucose measurement signal and determining a current risk metric associated with the detected glucose state. The method may include identifying a reference glucose state and a reference risk metric associated with the reference glucose state, and calculating an adjustment to a basal rate of a therapy delivery device based on the current risk metric associated with the detected glucose state and the reference risk metric associated with the reference glucose level.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: July 28, 2020
    Assignee: Roche Diabetes Care, Inc.
    Inventors: David L. Duke, Abhishek S. Soni
  • Patent number: 10716896
    Abstract: Systems and methods for automatically delivering medication to a user. A sensor coupled to a user can collect information regarding the user. A controller can use the collected information to determine an amount of medication to provide the user. The controller can instruct a drug delivery device to dispense the medication to the user. The drug delivery device can be a wearable insulin pump that is directly coupled to the user. The controller can be part of or implemented in a cellphone. A user can be required to provide a confirmation input to allow a determined amount of insulin to be provided to the user based on detected glucose levels of the user. The sensor, controller, and drug delivery device can communicate wirelessly.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 21, 2020
    Assignee: INSULET CORPORATION
    Inventors: Jason O'Connor, Daniel Allis, David Nazzaro, John R. Bussiere, John D'Arco
  • Patent number: 10708102
    Abstract: A simultaneous wireless information and power transmission method includes: transmitting an energy transfer signal comprising a peak-to-average power ratio (PAPR) corresponding to information to be transmitted at a first side; measuring the PAPR by receiving the energy transfer signal at a second side; and recovering the information from the measured PAPR at the second side.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: July 7, 2020
    Assignee: Research & Business Foundation Sungkyunkwan University
    Inventors: Dong In Kim, Jong Ho Moon, Jong Jin Park, Kang Yoon Lee
  • Patent number: 10664569
    Abstract: A computer-implemented system and related method of reporting glucose information for a user of a diabetes management device are presented here. An embodiment of the method obtains input data for the user of the diabetes management device, and identifies a tracked glycemic response event. One or more recommended glycemic control parameters are calculated based on an analysis of the obtained input data. The glycemic control parameters are calculated to extend a time period during which the user remains within a target glucose range following the tracked glycemic response event. The method continues by generating an output message that includes at least some of the recommended glycemic control parameters, and delivering the generated output message to a user device operated by the user of the diabetes management device.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: May 26, 2020
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Chantal M. McMahon, Pratik Agrawal, Yuxiang Zhong, Boyi Jiang, Huzefa F. Neemuchwala, Amit J. Rushi