Sensor Controls Pump, Motor, Or Pressure Driven Means Patents (Class 604/67)
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Patent number: 7291126Abstract: A drug delivery device includes a pressurized reservoir in communication with a flow path to an outlet. The flow path includes two normally-closed valves and a flow restriction. A pressure measurement arrangement measures a differential fluid pressure between two points along the flow path which span at least part of the flow restriction, one of the points being between the valves. A controller selectively opens the valves to deliver a defined quantity of the liquid medicament to the outlet.Type: GrantFiled: May 29, 2003Date of Patent: November 6, 2007Assignee: Nilimedix Ltd.Inventor: Avraham Shekalim
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Patent number: 7267661Abstract: Liquid infusion apparatus includes non-magnetic materials in a pumping structure and drive motor therefor, and in a controller that supplies drive signals to the motor to facilitate convenient operation in intense magnetic fields without distorting the magnetic fields and without radiating objectionable radio-frequency interface.Type: GrantFiled: June 17, 2002Date of Patent: September 11, 2007Assignee: Iradimed CorporationInventor: Roger E Susi
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Patent number: 7255680Abstract: A fluid delivery system includes a first fluid container having infusion fluid for a patient. The first fluid container has an outlet and a conduit attached to the outlet. A second fluid container applies pressure to the first fluid container to force fluid out of the first container and into the conduit at a desired flow rate. A pressure sensor is coupled to the second fluid container and a flow sensor is coupled to the conduit. The processor monitors the flow rate and controls the duty cycle of a downstream flow control actuator to maintain the desired flow rate. The processor determines the downstream resistance of the system by varying the flow rate about the selected flow rate, receiving pressure signals from the pressure sensor and flow signals from the flow sensor, and calculating the change in pressure over the change in flow rate to produce the fluid resistance measurement.Type: GrantFiled: October 27, 1999Date of Patent: August 14, 2007Assignee: Cardinal Health 303, Inc.Inventor: James E. Gharib
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Patent number: 7238165Abstract: A pumping system 10 provides a physiological pulsatile flow and includes controller 121, a pump drive head 50 coupled to a motor 12 and a fluid housing 52 having at least one port 60. The port 60 includes a ball valve retainer region 69, a valve seat 73, and an occluder ball 71 disposed in the ball valve retainer region 69. During operation, the motor 12 forces the fluid in and out the fluid housing 52 and causes the occluder ball 71 to move from a first position whereby the fluid cannot pass through the port 60, to a second position whereby the fluid moves annular to and generally around the occluder ball 71. This movement creates a slight flow reversal that “breaks up” any blood clots that may form. The pumping system may be used as part of a cardiopulmonary bypass system, a ventricular assist device (VAD) and/or a heart pump.Type: GrantFiled: February 21, 2003Date of Patent: July 3, 2007Assignee: Design Mentor, Inc.Inventors: Douglas Vincent, Matthew J. Murphy
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Patent number: 7231263Abstract: A method for controlling an insulin pump through the Internet. The method comprises the steps of ascertaining whether a logged-in person is a physician; determining the logged-in person as a nurse when the logged-in person is not a physician, receiving a patient's blood sugar level data and generating a command to change an insulin injection amount; checking whether the logged-in person is an attending physician when the logged-in person is a physician, and changing the logged-in person to an attending physician when the logged-in person is not an attending physician; and driving a corresponding insulin pump having the patient's ID by transmitting through the Internet and Bluetooth modules a new prescription made in consideration of a current blood sugar level measurement and insulin injection amount, when the logged-in person is an attending physician or when the logged-in person is changed to an attending physician.Type: GrantFiled: October 10, 2006Date of Patent: June 12, 2007Inventor: Soo Bong Choi
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Patent number: 7229430Abstract: A method and apparatus for reducing the workload of titrating drug to effect while leaving clinician users in control of a related procedure is described. A drug delivery device is controlled to achieve a target drug concentration at a selected site in the patient or a predetermined infusion rate waveform. The time profile of the target drug concentration or a predetermined infusion rate waveform is controlled by a drug state model that uses clinical heuristics to implement safe, pre-defined changes in the target drug concentration or infusion rate and user-commanded changes in target drug concentration or infusion rate. The invention allows time to assess the response of the patient to changes in drug level by making small incremental and conservative changes in drug level over time.Type: GrantFiled: July 31, 2002Date of Patent: June 12, 2007Assignee: Scott Laboratories Inc.Inventors: Randall S. Hickle, Jason Derouen
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Patent number: 7226430Abstract: A closed loop feedback drug delivery system for controlling muscle activity, e.g., spasticity. The system includes a sensor, e.g., an EMG sensor, for monitoring muscle activity and generating a detected muscle activity signal. A controller automatically adjusts at least one of timing and dosage of a drug administered to control muscle activity based on the detected muscle activity signal and produces a control signal. Administering of the drug, e.g., an antispasmodic drug, for controlling muscle activity based on the control signal is performed by an infusion pump. The drug after being emitted from the pump is then delivered to the spinal cord of the patient using an intrathecal catheter.Type: GrantFiled: December 26, 2003Date of Patent: June 5, 2007Assignee: Codman & Shurtleff, Inc.Inventor: Lev Ludin
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Patent number: 7214210Abstract: A disposable cassette for mixing an intravenous drug in a vial to a patient includes a liquid inlet for connection to a liquid supply, a first vial spike, a second vial spike and a chamber. The chamber, the first and second vial spikes, and the liquid inlet are in fluid communication with each other. A valve mechanism may be actuated to control flow between the chamber, the vial receptacles and the liquid inlet.Type: GrantFiled: March 16, 2004Date of Patent: May 8, 2007Assignee: DEKA Products Limited PartnershipInventors: Dean Kamen, Charles M. Grinnell, Marc A. Mandro, Dennis Gilbreath, Kevin Lee Grant, Jason A. Demers, William T. Larkins, Robert Manning, Richard J. Lanigan
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Patent number: 7211063Abstract: The present invention is an apparatus for treating a selected patient tissue or organ region, at the surface of such region. The apparatus has an accessing tool for accessing the patient region, the tool having a distal end, and a proximal end at which the tool can be manipulated to place the distal end adjacent to the patient region. The apparatus also has a probe carried on the distal end and defining a contact surface that may be urged against the patient region thereby creating contact pressure. A pressure transducer is operatively coupled to the probe and is capable of producing a measurable response to the contact pressure. A monitoring device is operatively connected to the pressure transducer, for determining the contact pressure. An effector is operatively disposed on the probe for producing a given effect on the patient region when the effector is activated, and an activator operatively connected to the effector, by which the effector can be activated.Type: GrantFiled: December 30, 2003Date of Patent: May 1, 2007Assignee: Boston Scientific Scimed, Inc.Inventor: Curtis P. Tom
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Patent number: 7204821Abstract: Apparatus for controlling the volume of surgical fluid present in a cavity in the body of a patient during surgery includes a conduit to the cavity for conducting the surgical fluid therefrom to at least one receptacle for receiving the fluid from said cavity. A source of vacuum assists in withdrawing fluid from the cavity and a vacuum controller interposed between the vacuum source and the receptacle controls the duration of time the receptacle is exposed to vacuum from the vacuum source. The apparatus preferably has a vacuum sensor for sensing vacuum levels in the receptacle when disconnected from the source of vacuum and shares the source of vacuum with another application, giving priority to maintaining a proper vacuum level in the receptacle.Type: GrantFiled: January 31, 2000Date of Patent: April 17, 2007Assignee: Ethicon, Inc.Inventors: Christopher R. Clare, Steve Griffiths
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Patent number: 7201734Abstract: Disclosed are devices for facilitating medical and/or procedures that are performed without “general anesthesia,” which is also described in the specification as the state of patient “unconsciousness” resulting from a drug administered by an anesthetist or anesthesiologist. The devices safely and effectively provide and maintain drug infusions that do not push the patient into unconsciousness and/or general anesthesia. Devices according to embodiments of the invention include the use of stored parameters and/or values that correlate to drug delivery during a procedure, and a patient health monitor to measure and send signals regarding a patient health condition to a processor.Type: GrantFiled: August 3, 2004Date of Patent: April 10, 2007Assignee: Scott Laboratories, Inc.Inventor: Randall S. Hickle
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Patent number: 7201733Abstract: A drug delivery system incorporated into a cardiac device for delivering a dose of a drug to a patient upon detection of a particular medical condition. The cardiac device may be, for example, an implantable cardioverter/defibrillator, cardiac pacemaker, or combination device that communicates via a radio frequency link with a drug delivery device. The drug delivery device is preferably an electrically modulated transdermal drug delivery device for delivering the drug transdermally in accordance with a signal received from the cardiac device.Type: GrantFiled: November 30, 2001Date of Patent: April 10, 2007Assignee: Cardiac Pacemakers, Inc.Inventors: Avram Scheiner, Mark Herner, Ronald W. Heil, Jr., Steven D. Girouard
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Patent number: 7195609Abstract: The invention relates to a piston stopper for an injection device, for injecting a medical or therapeutic product by axially advancing a piston stopper into a product container, wherein the piston stopper includes a stopper body and a stopper body holder detachably connected to it, and wherein a membrane body is placed like a cap onto the stopper body and connected to it, the membrane body being formed from an elastic material, while the stopper body and the stopper body holder are manufactured from an inflexible material. The invention encompasses an embodiment wherein the stopper body holder supports a sensor which measures the pressure acting on the membrane body to enable the pressure to be monitored precisely, in order to detect leaks and blockages in injection devices.Type: GrantFiled: June 13, 2003Date of Patent: March 27, 2007Assignee: Disetronic Licensing AGInventor: Serge Huegli
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Patent number: 7186247Abstract: A medical delivery system for delivering a fluid to a desired location within a body that includes a first member having an aperture, and a second member adapted to be positioned over the first member. The fluid to be delivered is contained within a fluid storage device, formed by at least one of the first member and the second member. The medical delivery system includes means for repositioning the first member relative to the second member between a first state preventing passage of the fluid through the aperture and a second state enabling passage of the fluid outward from the fluid storage device through the aperture.Type: GrantFiled: April 4, 2003Date of Patent: March 6, 2007Assignee: Medtronic, Inc.Inventors: Michael R. Ujhelyi, Rahul Mehra, Xiaoyi Min
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Patent number: 7175588Abstract: A pump system includes an implantable pump including a motor having a rotor and a stator. The stator includes a plurality of stator windings, and a motor controller is coupled to the motor to energize the windings so as cause the rotor to turn. A time-based system parameter of the pump is sampled and the system parameter is analyzed to calculate a suction probability index that provides an indication of the imminence of ventricle collapse.Type: GrantFiled: January 8, 2003Date of Patent: February 13, 2007Assignee: Micromed Technology, Inc.Inventor: Gino F Morello
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Patent number: 7172569Abstract: A method and a device for determining the blood flow QF in a vascular access (F) during an extracorporeal blood treatment is described, where the blood enters the blood treatment unit (3) of the blood treatment machine through an arterial branch (19) of an extracorporeal circulation loop (2) which is in fluid connection with the vascular access at an arterial connection. The blood is returned through a venous branch (21) of the extracorporeal circulation, which is in fluid connection with the vascular access at a venous connection (13). The blood flow in the vascular access is determined by measuring the pressure part, pven, in the arterial and/or venous branch of the extracorporeal circulation when the vascular access is open and interrupted, while the extracorporeal blood flow QB is varied. Then the fistula flow QF is determined from the measured values for the arterial and/or venous pressure while the vascular access is open and interrupted.Type: GrantFiled: October 28, 2004Date of Patent: February 6, 2007Assignee: Fresenius Medical Care Deutschland GmbHInventor: Wolfgang Kleinekofort
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Patent number: 7148786Abstract: A network communication and messaging protocol for use in a medical perfusion system, provides the rules which govern how, among other things, information and data is conveyed between the various devices which are connect to the network. The rules define the different types of messages that are used in conveying information and data, as well as the formatting for each of those message types. The various messages provide the ability to configure the perfusion system devices, establish links between the perfusion system devices, and convey various types of information and data, even when the main network controller is unavailable.Type: GrantFiled: February 21, 2002Date of Patent: December 12, 2006Assignee: Terumo Cardiovascular Systems CorporationInventors: Richard M. Willems, Richard A. Nazarian, James R. Watts
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Patent number: 7140843Abstract: Fluid pump for medicinal, especially endoscopic, applications having a transport channeled through a drive, a device possessing a measuring chamber for measuring the pressure of the fluid conveyed in the transport channel and control means for the automatic control of the behavior of the pump, in particular its transport behavior, as a function of the measured pressure and as a function of a code value contained in code value carrier means which are provided on or in the measuring chamber, wherein the code value is detected during and/or after fixing of the measuring chamber on the pump housing by read-out means in the fluid pump.Type: GrantFiled: July 7, 2003Date of Patent: November 28, 2006Inventor: Richard Korejwo
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Patent number: 7141037Abstract: The concentration of air in a fluid delivery line is determined by monitoring output signals corresponding to the amount of air detected in the fluid and processing those signals along with information as to the time or total volume of fluid dispensed since each signal was produced. The processor determines an air concentration value based on the received signal values, with the air concentration value determined by giving greater weight to more recent signal values. Where the air concentration value exceeds a predetermined value, an alarm signal may be activated or fluid delivery may be stopped. The processor also may determine a secondary air concentration value, which may be determined from the raw signal values instead of the weighted signal values. Where the secondary air concentration value exceeds a second predetermined threshold, an alarm signal may be activated or fluid delivery may be stopped.Type: GrantFiled: September 5, 2003Date of Patent: November 28, 2006Assignee: Cardinal Health 303, Inc.Inventors: Robert D. Butterfield, Allen B. Farquhar
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Patent number: 7137964Abstract: A device for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port, a local processor programmed to cause a flow of fluid to the exit port based on flow instructions from a separate, remote control device, and a wireless receiver connected to the local processor for receiving the flow instructions. The device also includes a housing free of user input components for providing flow instructions to the local processor, in order to reduce the complexity and costs of the device so that the device lends itself to being disposable in nature. A system and a kit are also described that include the fluid delivery device, a separate, remote control device, and accessories for transcutaneous delivery of fluid medications. Methods of utilizing the fluid delivery device to infuse fluid medications are additionally disclosed.Type: GrantFiled: October 28, 2003Date of Patent: November 21, 2006Assignee: Insulet CorporationInventor: J. Christopher Flaherty
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Patent number: 7138806Abstract: The invention relates to a device for detecting the position of a rotor relative to a stator, wherein at least one electrode is arranged on the rotor and at least one electrode is arranged on the stator, such that the electrodes at least partially overlap in at least one rotational position of the rotor relative to the stator, and encompasses a method for measuring the rotational position of a rotor including at least one rotor electrode relative to a stator including at least one stator electrode, wherein the rotational position is detected using a capacitive coupling between the rotor electrode and the stator electrode.Type: GrantFiled: January 9, 2004Date of Patent: November 21, 2006Assignee: TecPharma Licensing AGInventors: Simone Gafner, Michael Krieftewirth, Beat Steffen, Julian Yeandel
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Patent number: 7112273Abstract: A method and device for adjusting a volumetric flow balancing system for an extracorporeal blood treatment system receives a pressure signal and calculates a compensation factor that is used to adjust the relative flow rates of the volumetrically balanced fluids. For example, in a hemofiltration system, the flow of waste and and replacement fluid may be balanced volumetrically. Ultrafiltrate may be pumped in a bypass circuit in such a system. The rate of ultrafiltrate flow may be adjusted by the compensation signal. The compensation signal may be empirically derived.Type: GrantFiled: September 26, 2003Date of Patent: September 26, 2006Assignee: Nxstage Medical, Inc.Inventors: William Weigel, Daniel Call, Dennis Treu
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Patent number: 7104763Abstract: A method is disclosed for determining the operating condition of a medical pump based on data derived from a pressure sensor and a position sensor. The pressure sensor generates pressure data by sensing the force on the pumping element. The position sensor generates position data by tracking the pumping cycle and determining the position of the pumping element. The pump pressure data and pump position data are processed and the calculated results compared with a pre-determined threshold value to determine the operating condition of the pump. The three main types of operating conditions of concern are the following: normal condition, where liquid is present and no leaks exist in pumping chamber; leak condition, where liquid is present but a leak exists in the pumping chamber; and air stroke condition, where the chamber contains some air.Type: GrantFiled: July 22, 2003Date of Patent: September 12, 2006Assignee: Abbott LaboratoriesInventors: Chad E. Bouton, Dale M. Radcliff, Steven R. Nelson, Clark E. Fortney
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Patent number: 7092796Abstract: A system and method for verifying that a particular fluid supply is connected to an infusion pump or pump channel. An upstream pressure sensor coupled to a fluid conduit associated with the fluid supply is used to provide pressure signals in response to pressure sensed in the conduit to a processor. In a connection verification mode, the processor is configured to receive the pressure signals and delay the flow control device of the infusion pump from moving fluid through the conduit until the processor detects a pressure change in the conduit indicated by the pressure signals to thereby verify that the particular fluid supply is connected to the infusion pump.Type: GrantFiled: November 14, 2003Date of Patent: August 15, 2006Assignee: Cardinal Health 303, Inc.Inventor: Timothy W. Vanderveen
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Patent number: 7092797Abstract: A flow control apparatus having a flow monitoring system capable of detecting and identifying flow present within the administration feeding set loaded to the flow control apparatus is disclosed. The flow control apparatus comprises a single sensor capable of detecting the presence or absence of fluid in the administration feeding set. A software subsystem may be operatively associated with the single sensor that is capable of identifying between upstream and downstream flow conditions present within the administration feeding set loaded to the flow control apparatus.Type: GrantFiled: May 25, 2004Date of Patent: August 15, 2006Assignee: Sherwood Services AGInventors: Robert B. Gaines, Joseph A. Hudson
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Patent number: 7083719Abstract: A method, system and apparatus for performing peritoneal dialysis are provided. To this end, in part, a medical system is provided that includes (i) a liquid pump; (ii) tubing in communication with the liquid pump; and (iii) at least one processor that operates with the liquid pump to: (a) pump liquid through the tubing, the tubing having an end and a hydrophobic filter at the end, the filter allowing air but not the liquid to escape from the end of the tubing, (b) receive a signal indicating a pressure increase inside the tubing, and (c) cause the pumping to stop when air has been purged substantially from the tubing.Type: GrantFiled: March 11, 2005Date of Patent: August 1, 2006Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Joseph H. Bowman, Jr., Loren M. Lundtveit, Jose Alvaro, Ben Kellam, Don Busby, Bruce Ming-Da Eu
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Patent number: 7077822Abstract: Apparatus and methods for regulating the appetite of an individual suffering from morbid obesity, the apparatus including a plurality of stimulation electrodes arranged longitudinally on at least one electrode support shaft for insertion within the hypothalamus for outputting electrical discharges to specific sites within the hypothalamus. Each of the plurality of stimulation electrodes may be independently controlled. Electrical discharge of various frequencies transmitted from one or more of the plurality of stimulation electrodes, and delivered to a region of the hypothalamus that is involved with either stimulating or inhibiting appetite, may be used to regulate appetite in the individual. Alternatively, an individual's appetite may be regulated by the microinfusion from at least one microinfusion catheter of an appropriate quantity of a suitable drug to a distinct site or region within the hypothalamus.Type: GrantFiled: September 13, 2000Date of Patent: July 18, 2006Assignee: The University of Iowa Research FoundationInventor: Matthew A. Howard, III
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Patent number: 7079886Abstract: A fluid injection arrangement in the context of patient imaging systems, in which phases of contrast medium injection and flushing medium injection can be freely and selectably ordered as to make available to the operator and patient a vast array of possible protocols that has hitherto been essentially unattainable. The arrangement provides a programmable KVO phase and the ability to program a first phase of injection procedure as a flushing medium phase.Type: GrantFiled: August 28, 2001Date of Patent: July 18, 2006Assignee: Medrad, Inc.Inventors: Doug Zatezalo, Jeffrey John Thompson, Steven C. Rygg, Scott R. Griffith, John Gardner, Ronald Barbati
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Patent number: 7074205Abstract: A modular patient care system having a central management unit module and one or more detachable functional units is described. Using unique mechanical and electrical features, the modular patient care system is capable of flexibly, bilaterally, and safely providing electrical power from the central management unit to the attached functional units, with exposed power leads of end units being electrically isolated for safety and security. Functional units are capable of detecting the presence of other functional units more distant from the central management unit for passing power to those units, and for otherwise electrically isolating exposed power leads when no further units are attached.Type: GrantFiled: August 23, 1999Date of Patent: July 11, 2006Assignee: Cardinal Health 303, Inc.Inventors: Robert J. Duffy, Lon M. Severe, Edward M. Richards, Shawn W. DeKalb, James P. Stewart, Dale Coleman, Timothy Vanderveen
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Patent number: 7070575Abstract: A feeding set adaptor and related system for delivering solutions utilize a feeding set adaptor which engages a pump engaging portion of an infusion set and the feeding set adaptor structure to provide monitoring portions for detecting pressures within the infusion set, a sample cell for determining the presence of air within an infusion set, and an anti-freeflow device for selectively preventing freeflow through the infusion set. The feeding set adaptor is configured for mounting on an infusion pump which moves solution through the infusion set for delivery to a patient.Type: GrantFiled: August 23, 2004Date of Patent: July 4, 2006Assignee: Zevex, Inc.Inventors: Kent F. Beck, James A. Malmstrom, Scott D. Miles
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Patent number: 7067061Abstract: A method for preparing a medical liquid from a liquid, such as water, and two concentrated solutions comprises the following steps: circulating the liquid in a conduit (15), at a flowrate Q0; injecting into the conduit (15), at a flowrate Q1, a first concentrated solution containing a first ionic substance A and a second ionic substance B, the ionic substances A and B having, respectively, in the first concentrated solution, a concentration [Asol] and a first concentration [B1sol]; injecting into the conduit (15), at a flowrate Q2, a second concentrated solution containing the first ionic substance A and the second ionic substance B, the first ionic substance A having, in the second concentrated solution, the same concentration [Asol] as in the first concentrated solution, and the second ionic substance B having, in the second concentrated solution, a second concentration [B2sol] different than the first concentration [B1sol] in the first concentrated solution; regulating the injection flowrate Q1 and theType: GrantFiled: May 13, 2004Date of Patent: June 27, 2006Assignee: Gambro Hospal (Schweiz) AGInventors: Antonio Bosetto, Francesco Paolini
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Patent number: 7060059Abstract: A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.Type: GrantFiled: October 14, 2003Date of Patent: June 13, 2006Assignee: Becton, Dickinson and CompanyInventors: Steven Keith, Robert S. Parker, Noel G. Harvey, Ronald J. Pettis, John D. DeNuzzio, Glenn Vonk
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Patent number: 7044930Abstract: The invention relates to an arrangement for inducing a state of anaesthesia in a living creature and maintaining the creature in that state by administering to the said creature an infused volume of liquid anaesthesia-inducing medication per unit of time, preferably during the use of one or more lung ventilation unit(s)s and one or more infusion unit(s). The arrangement comprises a basic unit (102) with control function software (600a?–600r?) and one or more modular unit(s) (30?, 30, 30?) containing hardware for the control functions. When a modular unit (30?) co-acts with the basic unit (102), it (30?) activates the control functions stored in the basic unit (102).Type: GrantFiled: January 24, 2001Date of Patent: May 16, 2006Assignee: Aneo ABInventor: Stefan Per Axel Stromberg
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Patent number: 7043295Abstract: Methods and systems for treating patients suffering from eating disorders, e.g. obesity, through the dispensation of a drug by an implantable infusion pump (IIP) delivering drug into the cerebral spinal fluid (CSF) at a site of the intrathecal space in amounts and at times effective to suppress the patient's appetite through interaction of the drug transported through the CSF with receptors in the brain. Delivery of a programmed drug dosage is preferably by one of time-out of programmed time(s) of day, a command received from the patient, or a trigger signal developed from a sensed GI tract signal accompanying peristalsis.Type: GrantFiled: April 26, 2002Date of Patent: May 9, 2006Assignee: Medtronic, Inc.Inventor: Warren L. Starkebaum
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Patent number: 7029455Abstract: A device for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port, a local processor programmed to cause a flow of fluid to the exit port based on flow instructions from a separate, remote control device, and a wireless receiver connected to the local processor for receiving the flow instructions. The device also includes a housing free of user input components for providing flow instructions to the local processor, in order to reduce the complexity and costs of the device so that the device lends itself to being disposable in nature. A system and a kit are also described that include the fluid delivery device, a separate, remote control device, and accessories for transcutaneous delivery of fluid medications. Methods of utilizing the fluid delivery device to infuse fluid medications are additionally disclosed.Type: GrantFiled: November 15, 2002Date of Patent: April 18, 2006Assignee: Insulet CorporationInventor: J. Christopher Flaherty
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Patent number: 7025757Abstract: A syringe loading/filling device (or “syringe loader”) includes a syringe mounting mechanism adapted to cooperate with an attachment mechanism of a syringe to attach the syringe to the syringe loader and a drive member adapted to impart motion to the syringe plunger. The syringes for use with the syringe loader include a syringe plunger slidably disposed therein and an attachment mechanism for attachment of the syringe to an injector. Such injectors include a mounting mechanism adapted to cooperate with the attachment mechanism on the syringe to mount the syringe on the injector.Type: GrantFiled: February 4, 2002Date of Patent: April 11, 2006Assignee: Medrad, Inc.Inventors: David M. Reilly, Frederick W. Trombley, III, Mark Trocki
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Patent number: 7001372Abstract: A therapeutic device and therapeutic method for delivering electrical energy or a medicament to a body tissue or organ utilizing ultrasonic vibration to cause a device implanted in the body tissue or organ to be treated to discharge an electrical current or medicament to the target area.Type: GrantFiled: February 23, 2004Date of Patent: February 21, 2006Assignee: Zuli Holdings, Ltd.Inventor: Jacob Richter
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Patent number: 6997896Abstract: An apparatus for controlling the pressure of a liquid, introduced into a body cavity, in order to facilitate a surgical procedure, utilizing an irrigation pump and conduit and at least one output device and conduit leading away from the body cavity for drawing off the liquid, and a control circuit for controlling the irrigation pump and output device such that a nominal pressure in the cavity may be maintained.Type: GrantFiled: March 11, 2003Date of Patent: February 14, 2006Assignee: Karl Storz GmbH & Co. KGInventor: Pavel Novak
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Patent number: 6986753Abstract: An irrigation system for a medical device. The irrigation system may include a pump that can pump irrigation fluid from a reservoir through an irrigation line. The system may further have a controller coupled to the pump and an accumulator pressure sensor that senses the pressure of the irrigation line. The controller can vary the speed of the pump in response to a change in the line pressure to control the irrigation line pressure. Additionally, the controller can monitor the fluidic resistance of the system by determining the pump speed and corresponding flowrate of the pump. The controller can provide one or more safety output signals if the fluidic resistance exceeds a threshold value(s).Type: GrantFiled: May 21, 1999Date of Patent: January 17, 2006Assignee: BuivisionInventor: Hai Bui
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Patent number: 6981960Abstract: In a cosed-loop process, a controller uses a flow sensor to monitor the flow of a medicinal fluid being infused into a patient, to achieve a desired rate of flow. A relatively inexpensive peristaltic pump or electronically controlled valve can be used to vary the flow of the medicinal fluid through a fluid line. A Y site within the fluid line includes an integral flow sensor having an orifice. The flow sensor includes proximal and distal pressure sensors disposed on opposite sides of the orifice to monitor the distal and proximal pressure, producing a signal indicative of the rate of flow of the medicinal fluid through the fluid line. A signal produced by the controller is input to a motor driving the pump or to the valve to vary the rate of flow as required to achieve the desired infusion rate of the medicinal fluid.Type: GrantFiled: December 4, 2003Date of Patent: January 3, 2006Assignee: Hospira, Inc.Inventors: Steve T. Cho, Gene E. Clark
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Patent number: 6979326Abstract: An infusion system for infusing a liquid into a body includes an external infusion device and a remote commander. The external infusion device includes a housing, a receiver, a processor and an indication device. The receiver is coupled to the housing and for receiving remotely generated commands. The processor is coupled to the housing and the receiver to receive remotely generated commands and to control the external infusion device in accordance with the commands. The indication device indicates when a command has been received and indicates when the command is being utilized to control the external infusion device so that the external infusion device is capable of being concealed from view when being remotely commanded. The remote commander includes a commander housing, a keypad for transmitting commands, and a transmitter for transmitting commands to the receiver of the external infusion device.Type: GrantFiled: March 27, 2003Date of Patent: December 27, 2005Assignee: Medtronic MiniMed, Inc.Inventors: Alfred E. Mann, James D. Causey, III, Alan Haubach, Luis J. Malave, John Livingston, Cliff Hague, Chad Srisathapat, Jay Yonemoto, Deborah Ruppert, Dennis P. Bishop, Adrian Gut, Bob Murtfeldt
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Patent number: 6969369Abstract: The invention is directed to techniques for monitoring the condition of a patient, such as a patient having congestive heart failure, and appropriately modifying the patient's drug therapy as a function of a pressure in the patient's heart, such as the estimated pulmonary artery diastolic pressure. The drugs may be administered by an implanted drug delivery device. The drug selection, the drug dosage or both may be controlled as a function of the pressure and/or the activity level of the patient.Type: GrantFiled: April 22, 2002Date of Patent: November 29, 2005Assignee: Medtronic, Inc.Inventor: Chester Struble
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Patent number: 6969382Abstract: A therapeutic device and therapeutic method for delivering electrical energy to a polymer containing a medicament that allows release of the medicament to a body tissue or organ. The device and method utilizes ultrasonic vibrations to cause the device, implanted in the body tissue or organ to be treated, to discharge an electrical current to the polymer containing the medicament. The medicament is controllably released to the target area by changing the charge of the polymer with the electrical current.Type: GrantFiled: January 21, 2003Date of Patent: November 29, 2005Assignee: Zuli Holdings, Ltd.Inventor: Jacob Richter
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Patent number: 6968226Abstract: A method and system is provided for responding, from internally within a patient, to an atrial arrhythmia in a heart including measuring from within the patient at least one electrocardiogram characteristic indicative of the atrial arrhythmia, and controlling from within the patient drug therapy delivery to the patient responsive to measuring the at least one electrocardiogram characteristic. Drug therapy is initiated to the patient responsive to measuring the at least one electrocardiogram characteristic. According to one aspect of the present invention, the drug therapy is staged within the patient prior to measuring the at least one electrocardiogram characteristic. According to another example embodiment, the heart is paced from within the patient at a predefined rate responsive to measuring the at least one electrocardiogram characteristic, pacing occurring alone, or in combination with drug therapy.Type: GrantFiled: January 30, 2002Date of Patent: November 22, 2005Assignee: Medtronic, Inc.Inventors: Rahul Mehra, George J. Klein, Michael R. Ujhelyi
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Patent number: 6966895Abstract: A syringe pump has a motor rotating a leadscrew to drive a plunger head actuator along it. The head actuator engages the plunger of a syringe and moves the plunger along the syringe barrel to dispense medication. An optical encoder mounted on the leadscrew is rotated by the motor to produce a pulse output. A control unit times the interval between the pulses and compares these timings with a stored value representative of a predetermined multiple of the minimum time. If the head actuator is obstructed, the speed of rotation of the motor is slowed and the time interval between pulses rises. When this exceeds the stored value, the control unit stops the drive to the head actuator and generates an alarm.Type: GrantFiled: August 3, 2001Date of Patent: November 22, 2005Assignee: Smiths Group PLCInventor: Robert James Tribe
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Patent number: 6949082Abstract: A medicament delivery device is disclosed having dose dial means 6,8 to determine a quantity of medicament to be delivered. The medicament delivery device is also provided with selection means to select whether the quantity of medicament to be delivered is determined as a multiple of a first quantum of units or as a multiple of a second quantum of units.Type: GrantFiled: December 21, 2001Date of Patent: September 27, 2005Assignee: Lea Design International LimitedInventors: Christopher Nigel Langley, Shane Alistair Day, Robert Frederick Veasey, Robert Woolston
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Patent number: 6949081Abstract: An interactive drug delivery system includes a drug delivery module, an optical probe, a local controller, and an optional central controller. The drug delivery module is constructed and arranged to deliver selected amounts of a drug into a subject. The optical probe is constructed and arranged to detect in a selected tissue region of the subject a manifestation caused by the delivered drug. The local controller is constructed and arranged to receive data from or transmit data to the optical probe and the drug delivery module. The local controller is arranged to correlate optical data, received from the optical probe, to selected data and provide signals to the drug delivery module for adjusting the amounts of the drug to be delivered into the subject.Type: GrantFiled: August 26, 1999Date of Patent: September 27, 2005Assignee: Non-Invasive Technology, Inc.Inventor: Britton Chance
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Patent number: 6945954Abstract: An automatic injection device includes a drive mechanism and a sensor used to determine an internal characteristic such as a force or internal pressure generated during an injection process. This characteristic is then used as a control parameter by a microprocessor or controller which generates corresponding commands to the drive mechanism. In a particularly advantageous embodiment, the characteristic is used to calculate an exit pressure at which fluid ejected by the device through an elongated tube. The drive mechanism is then operated in such a manner that the exit pressure is maintained at a predetermined level to insure that a patient does not suffer pain and/or tissue damage.Type: GrantFiled: January 22, 2001Date of Patent: September 20, 2005Assignee: Milestone Scientific, Inc.Inventors: Mark Hochman, Claudia Hochman, Angelo Ascione, Lawrence Brown, Hardie Johnson, Michelle Lockwood
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Patent number: 6942637Abstract: A rapid infusion system for the intravenous delivery of fluids at standard and rapid flow rates. The system includes a pump assembly, a drive assembly to power the pump, and a fluid containment system that keeps the infused fluid out of direct contact with the pump assembly and that is preferably disposable and removable. In one embodiment the drive assembly includes a differential drive that interacts with more than one motor. In one embodiment, the pump assembly includes a roller pump and the pump chamber is a collapsible, preformed tube that is preferably attached to a pump cartridge frame. Optionally, the system includes a self-leveling drip chamber and the fluid containment system is disposable and includes a pump cartridge containing the drip chamber and the pump chamber, I.V. tubing, outlet infusion tubing, and a heater cartridge.Type: GrantFiled: March 6, 2003Date of Patent: September 13, 2005Assignee: Smisson-Cartledge Biomedical LLCInventors: Richard G. Cartledge, Hugh F. Smisson, III, Jeffery O. Brown
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Patent number: 6939111Abstract: A method, system and apparatus for performing peritoneal dialysis are provided. To this end, in part, a method of controlling pressure in a medical fluid pump is provided. The method includes the steps of controlling a pump member acceleration during a first portion of a pump stroke and adaptively changing the pump member velocity during a second portion of the pump stroke.Type: GrantFiled: May 24, 2002Date of Patent: September 6, 2005Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Bruce Huitt, Peter Hopping, Rick Kienman