Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Abstract: A laser can produce pulses of light energy to eject a volume of the tissue, and the energy can be delivered to a treatment site through a waveguide, such as a fiber optic waveguide. The incident laser energy can be absorbed within a volume of the target tissue with a tissue penetration depth and pulse direction such that the propagation of the energy from the tissue volume is inhibited and such that the target tissue within the volume reaches the spinodal threshold of decomposition and ejects the volume, for example without substantial damage to tissue adjacent the ejected volume.

Abstract: A method for treating presbyopia utilizes an Erbium based, pulsed laser to sever sub-conjunctival strictures located within the scleral matrix of the eye. Introduction of treatment energy into the scleral matrix increases or facilitates an increase in accommodation, thereby mitigating the effects of presbyopia. The treatment energy can be directed into the scleral matrix to form tunnel ablations in and through the strictures of the scleral matrix. The tunnel ablations can enhance the accommodation of the patient's eye, enabling the eye to refocus at near distances while not losing its ability to focus at a distance.

Abstract: A cardiac ablation instrument capable of removing blood from a treatment area is provided. The instrument includes a catheter configured to deliver a distal end thereof to a patient's heart. The instrument can also include an expandable element coupled to the distal end of the catheter wherein the expandable member is configured to be positioned adjacent a target area thereby defining a treatment area between the expandable member and the target area. Further, the instrument can include an irrigation mechanism configured to dispense an irrigation fluid from the catheter thereby displacing blood from the treatment area. Additionally, the instrument includes an energy emitter configured to deliver energy to tissue within the treatment area. The instrument can also include a contact sensor configured to determine the presence of such blood within the treatment area. Methods for ablating tissue are also provided.

Abstract: The present invention provides devices and methods for applying radiation to the retina of a patient. In one embodiment, an apparatus includes a radiation source for generating a radiation beam suitable for absorption by retinal pigment epithelial cells. One or more optical components are included to direct the beam onto the retina. A scanner is optically coupled to the radiation source to control movement of the beam in two dimensions to allow a scan over the retina. A controller applies control signals to the scanner to adjust beam movement to illuminate a plurality of retinal locations in a temporal sequence according to a predefined pattern. The device can be operated in one mode to effect selective targeting of retinal pigment epithelial cells, or in another mode to effect thermal photocoagulation of the retina.

Abstract: A laser treatment apparatus for irradiating a laser beam to a patient's eye, comprises: a plurality of laser sources which emit treatment laser beams having different wavelengths, each laser source being held in a main body to be mountable and demountable and connected to a power source through a connector; a light delivery optical system having a mirror for making the laser beams from the laser sources coaxial with each other to deliver each laser beam to the patient's eye; an input unit for inputting mounting information of each laser source; a control unit which checks a predetermined operation of each laser source by a sensor at the time of activation to determine whether an abnormality is present or not in each laser source, and displays an indication that the abnormality is present on a display, wherein the control unit will not perform the operation check whether the abnormality is present or not in the laser source or laser sources unmounted in the main body, based on the mounting information input by

Abstract: The invention relates to a method of treating obesity, insulin resistance and co-morbidities of these conditions by removing tissue from the abdomen. More specifically, it relates to a method of removing abdominal fat and omentum to which the fat is attached, in order to improve health.

Abstract: An apparatus and process using a high-power, short-pulsed thulium laser to output infrared laser pulses delivered through an optical fiber, for cutting and ablating biological tissue. In some embodiments, the pulse length is shortened sufficiently to keep inside the stress-confined ablation region of operation. In some embodiments, the pulse is shortened to near the stress-confined ablation region of operation, while being slightly in the thermal-constrained region of operation. In some embodiments, the laser is coupled to a small low —OH optical fiber (˜100 ?m diameter). In some embodiments, the device has a pulse duration of about 100 ns for efficient ablation; however in some embodiments, this parameter is adjustable.

Abstract: A method and apparatus are provided for processing a hard material, for example a hard biological material such as dental enamel or bone, with optical radiation. A treatment zone of the material is selectively cleaned of ablation products and other dirt to enhance processing efficiency, and a tip through which the optical radiation is applied to the treatment zone of the hard material is spaced slightly from the treatment zone during at least a portion of the time that hydrating fluid is being applied to the zone and/or while air or another gas is applied to the zone to clean the surface thereof.

Abstract: A stand-alone laser device that provides low level laser therapy using one or more laser sources. The laser sources are attached to one or more arms which can be positioned to cause the laser light to impinge on a desired area of a patient's body. A scanning apparatus is attached to the arms which comprise structures that cooperate to cause an optical element to be able to simultaneously rotate about a central axis and move in a linear motion along that axis to achieve any desired scan pattern. Laser light of different pulse widths, different beam shapes and different scan patterns can be applied externally to a patient's body. In the preferred embodiment, red light having a wavelength of about 635 nm is used to stimulate hair growth on a patient's scalp.

Abstract: Disclosed herein are methods and systems for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production).

Abstract: Switching power supplies made in accordance with the disclosed technology drive flash lamps of dermatologic treatment devices to emit a sequence of relatively small light pulses that are aligned with particular locations within the waveform of the AC line source. Such power supplies not only enable sufficient light energy in aggregate to therapeutically heat target chromophores in a skin region without causing undesired damage to surrounding tissue, but also provide the added benefit that the corresponding electrical energy need not be substantially drawn from any charged capacitor. The disclosed power supply further compensates for performance degradation of the flash lamps during their usable life, by modifying its operation based on predetermined values that are indicative of flash lamp aging/efficiency characteristics. The flash lamps and their associated stored values are preferably incorporated into a replaceable cartridge that facilitates user maintenance of the dermatologic treatment device.

Abstract: In a fractional treatment system, an adjustable mechanism can be used to adjust the beam shape, beam numerical aperture, beam focus depth, and/or beam size to affect the treatment depth and or the character of the resulting lesions. Adjustment of these parameters can improve the efficiency and efficacy of treatment. Illustrative examples of adjustable mechanisms include a set of spacers of different lengths, a rotatable turret with lens elements of different focal distances, an optical zoom lens, and a mechanical adjustment apparatus for adjusting the spacing between two optical lens elements. In one aspect, the fractional treatment is configured with a laser wavelength that is selected such that absorption of the laser wavelength within the tissue decreases as the tissue is heated by the laser (e.g., 1480-1640 nm).

Abstract: The invention involves a device and a procedure for refractive laser surgery on a target object. With the aid of a laser beam source, an fs-impulse laser beam is generated. A second laser beam source generates a UV laser beam. A shared scanner device utilises the fs-impulse laser beam and the UV laser beam for the scanning of the target object.

Abstract: An apparatus and method for auto-titrating a surgical laser are disclosed. One embodiment of the method comprises: providing an algorithm, wherein the algorithm is operable to configure the laser based on one or more user inputs; providing a first user input operable to cause the algorithm to execute and fire the laser in a defined pattern; providing a second user input, in response to an observed condition, operable to cause the laser to stop firing and to cause the algorithm to determine one or more laser parameter values and configure the laser based on the one or more laser parameter values, wherein a final laser power value when the laser stops firing is an input to the algorithm and wherein the algorithm determines the one or more laser parameters based on the final laser power value. The method can further comprise placing the laser in a “ready” (surgical) mode, either automatically by the auto-titration algorithm or via another user input.

Abstract: Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such that an operator can detect penetration of the epithelial layer.

Abstract: A catheter system is provided comprising a laser catheter with a fibre bundle of optical fibres emitting a light beam in the distal direction of the catheter and a laser apparatus, comprising one or more lasers for supplying light to the optical fibres. The catheter system is preset or adjusted for emitting a pulsating light beam with an ablation power of at least 40 mJ/mm2 per pulse at the location of a light emitting surface. A method for preparing such a catheter system is provided comprising the step of a) measuring said ablation power at the location of the light emitting surface; b) comparing the measured ablation power with a predefmed power value requirement; c) in case the measured ablation power is different from the predefmed power value requirement, adjusting the ablation power of the pulsating light beam to meet the predefined power value requirement.

Abstract: An illumination device for use in an ophthalmic surgical apparatus, the illumination device including a fiber optic having a proximal end and a connector coupled to the fiber optic. The connector includes one or more of (1) a datum surface disposed a predetermined distance from the proximal end to position the proximal end at a predetermined location within the surgical apparatus, (2) a shutter actuation surface configured and arranged to open a shutter in the surgical apparatus when the connector is being connected to the surgical apparatus, and (3) a visual indicator position to provides a visual indication that the connector is fully inserted into the surgical apparatus. The illumination device may be in a combination with an ophthalmic surgical apparatus.

Abstract: A system for measuring real-time tissue reflection spectral characteristics during ablation includes a catheter for collecting light reflected from tissue undergoing ablation, a detection component for separating constituent wavelengths of the collected light, a quantification apparatus for generating measured light intensity data of the collected light, and a processor for analyzing the data in relation to time. A method for monitoring formation of steam pop during ablation includes delivering light to tissue, delivering ablative energy to the tissue, measuring the reflectance spectral intensity of the tissue, and observing whether the measured reflectance spectral instensity (MRSI) initially increases in a specified time period followed by a decrease at a specified rate. If the MRSI does not decrease, delivery of ablation energy continues.

Abstract: The catheter (1) has a fastener (10) for firmly holding the wall (19) of vessel (18) when it is cut by optical fibers (3). The fastener (10) has an engaging element which can be a pin (20), roughened surface (23), spiral grooves (27), dendritic grooves (31), adhesive surface (34) or pointed pins (38).

Abstract: Systems and methods for providing light therapy traction to a patient. A light therapy device and a traction mechanism provide concurrent, alternating and/or repetitive treatment to a patient. The light therapy device includes one or more light sources configured to deliver light to a patient. The traction mechanism is configured to provide selective separation to a particular location the patient's body, such as a location of the patient's vertebrae. In some embodiments, the light therapy and traction are performed simultaneously. In other embodiments, the light therapy and lumbar traction are performed in treatment cycles to the patient. Embodiments of the present invention embrace the application of light therapy prior to, during, and/or after a cervical and/or lumbar traction treatment.

Abstract: A surgical instrument that comprises at least one microcontroller arranged in the handle of the instrument and that communicates with the surgical apparatus—without the interposition of a radio link via the cable that already exists between the surgical apparatus and the surgical instrument. Safe data transmission is ensured not only in the high-interference environment of an active RF surgical apparatus, but also in water jet, argon plasma and cryosurgical apparatuses, endoscopes or the like. A differential transmission technique is selected, wherein one or more conductor pairs (insulated conductors) are utilized, one of the conductors of said conductor pairs transmitting the signal and the other transmitting the inverted signal. By subtracting the two signals, the actual data signal is yielded on the receiver side. If feedback interferences from the environment act on the data transmission link, the subtractions performed on the respective receivers cancels out the interferences.

Abstract: A system and method for increasing the amplitude of accommodation and/or changing the refractive power of lens material of a natural crystalline lens is provided. Generally, there is provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of sectional patterns results in the shaped structural weakening of the lens. There is also provided a method and system for determining adjustments to refractive errors in the lens of an eye relating to the treatment of presbyopia. The change to refractive error can be a predicted error or an actual error that has been determined.

Abstract: The present invention relates to a laser beam control structure and method. A laser beam control structure of the present invention comprises a handpiece for irradiating laser beams output from a laser beam output device, on a predetermined part; at least one electrode unit positioned at a human body contact portion of the handpiece and receiving hum noise generated from a human body; and a control unit electrically connected to the electrode unit so as to measure the hum noise applied from the electrode unit and to cause the laser beams to be irradiated according to the measured hum noise. According to the present invention, there are advantages in that various types of hum noise generated from a human body are measured without applying an electric current to the human body, and a laser beam is irradiated according to the measured hum noise.

Abstract: An improved dental laser system includes a DC power section that rectifies its AC electrical input energy in a format suitable for both CW and pulsed operation, an RF power supply operating in a range of about 40 to 125 MHz and configured for both CW and high peak power pulsing operation, a sealed-off, RF excited CO2 waveguide or slab resonator laser filled to a gas at a pressure between about 260 to 600 Torr (or about 34,700-80,000 Pa), and a beam delivery system to steer the beam from the output of the laser to the mouth, such as the patient's mouth.

Abstract: Various methods and devices are provided for navigating through bone. In one embodiment, a bone navigation device is provided and includes a bone penetrating member configured to be implanted in bone and having at least one optical waveguide extending therethrough. The optical waveguide is adapted to illuminate tissue surrounding the device and to receive reflected/transmitted light from the tissue to determine the optical characteristics of the tissue, thus facilitating navigation through the tissue. At least one window can be formed in the bone penetrating member for allowing light from the at least one optical waveguide to illuminate the tissue, and for receiving the reflected light.

Abstract: A method for the treatment of skin including the steps of determining the skin depth for energy absorption necessary for treatment; and generating a spot size for energy impinging on the skin to provide a desired amount of energy to the desired depth for treatment. In one embodiment the selected spot size has a small diameter. In another embodiment the spot diameter is narrower than the spacing between adjacent hairs on the skin. In another aspect the invention relates to an apparatus for the treatment of skin including a source of energy; and a means for selecting a spot size for energy from the source impinging on the skin to provide a desired amount of energy to a desired depth for treatment. In another embodiment the apparatus includes an interlock to prevent the laser from producing light unless the source is positioned to irradiate only the skin.

Abstract: Disclosed is an apparatus for ophthalmological, in particular, refractive laser surgery, which aligns a required ablation profile on a specified corneal point, which it calculates from the image data of an eye tracker, taking account of the depth of the anterior chamber of the eye, including the depth of the cornea, calculated individually for the respective patient.

Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.

Abstract: A surgical system includes a surgical laser source operable to emit a surgical laser beam and an OCT engine operable to emit an OCT beam. The surgical system also includes an endoprobe optically coupled to the surgical laser source and the OCT engine. The endoprobe includes an OCT fiber for transmitting the OCT beam, a surgical laser fiber for transmitting the surgical laser beam, and scanning optics optically coupled to the OCT fiber and the surgical laser fiber, the scanning optics configured to simultaneously scan both the OCT beam and the surgical laser beam. The surgical system further includes a processor programmed to control the scanning optics to scan the OCT beam and the surgical laser beam over a targeted tissue area and to detect an OCT signal from the targeted tissue area.

Abstract: To irradiate a laser beam appropriately onto a patient's eye. An ophthalmic apparatus having a laser irradiation optical system irradiating a laser beam for corneal surgery onto the eye, which performs alignment of a reference axis of the optical system to have a predetermined positional relationship with the eye to perform laser irradiation, includes movement means changing inclination and a position of the optical system with respect to the eye, first and second image-pickup means picking up anterior-segment images having image-pickup optical axes arranged in different directions and to have predetermined positional relationships with the reference axis, detection means for detecting inclination and a position of the eye with respect to the reference axis by subjecting the images by the image-pickup means to image processing, and control means controlling the movement means to bring the reference axis to an intended alignment state with the eye based on a detection result.

Abstract: An apparatus and process using a high-power, short-pulsed thulium laser to output infrared laser pulses delivered through an optical fiber, for cutting and ablating biological tissue. In some embodiments, the pulse length is shortened sufficiently to keep inside the stress-confined ablation region of operation. In some embodiments, the pulse is shortened to near the stress-confined ablation region of operation, while being slightly in the thermal-constrained region of operation. In some embodiments, the laser is coupled to a small low —OH optical fiber (˜100 ?m diameter). In some embodiments, the device has a pulse duration of about 100 ns for efficient ablation; however in some embodiments, this parameter is adjustable.

Abstract: The present invention provides devices and methods for applying radiation to the retina of a patient. In one embodiment, an apparatus includes a radiation source for generating a radiation beam suitable for absorption by retinal pigment epithelial cells. One or more optical components are included to direct the beam onto the retina. A scanner is optically coupled to the radiation source to control movement of the beam in two dimensions to allow a scan over the retina. A controller applies control signals to the scanner to adjust beam movement to illuminate a plurality of retinal locations in a temporal sequence according to a predefined pattern. The device can be operated in one mode to effect selective targeting of retinal pigment epithelial cells, or in another mode to effect thermal photocoagulation of the retina.

Abstract: The above described apparatus and methods provide the possibility to reduce or even eliminate the effects of delay between image acquisition and laser ablation. Thus this will lead to less positioning errors and therefore to better ablation results in laser refractive surgery. The importance of this invention will increase with decreasing ablating beam diameter. The use of synchronization leads to shorter delay times. Hence it follows that the duration of the whole treatment decreases as well.

Abstract: Systems and methods provide for stabilizing the amount of laser energy delivered to a target from a laser device. Generally, delivered laser energy is measured over multiple laser pulses or over time in the case of a constant wave laser. A decrease is then calculated in the delivered energy, the decrease being caused by accumulation of one or more substances, such as ozone, along the laser beam delivery path due to passage of the laser beam along the path. Using this calculated decrease, a laser device may be adjusted to compensate for the decrease in delivered energy due to the accumulated substance(s), thus stabilizing the amount of energy delivered to the target.

Abstract: An apparatus is disclosed for monitoring a thermal surgical procedure including a thermal camera for monitoring temperature at a plurality of locations within at least a portion of a surgical field undergoing thermal surgical treatment and generating a series of thermal images based on said monitoring, a processor for processing the thermal images, and a display for displaying, in real time, a series of display images indicative of temperature at the plurality of positions.

Abstract: Laser surgery devices and methods of performing laser surgery using laser surgery devices are described. The laser surgery device may rotate a laser fiber along a longitudinal axis of the laser fiber in a repeating pattern through a user-specified rotational pattern. The laser surgery device may be optionally attached to a surgical device to implement hands-free operation of the laser surgery device.

Abstract: A controller, an external electrode and a probe to be inserted into a tissue volume. One end of the probe is terminated by one or more electrodes and the other end is connected to a load cell. The electrode end of the probe is inserted into a volume of adipose tissue to be treated. Intermittently different and low power RF energy is applied between the external electrode and the electrodes of the probe. Monitoring of the impedance between the external electrode and the probe electrodes enables probe guidance. Monitoring of the impedance between the probe electrodes helps characterize the aggregate state of the treated tissue volume and treatment end-point.

Abstract: Methods and systems for treating skin for aesthetic or health purposes are described. According to various embodiments, photoresponsive materials and light are delivered in a controlled fashion to produce a patterned distribution of a material in the skin.

Abstract: The present invention discloses a high power diode-pumped laser for laser ablation of soft tissue. The present invention contemplates to operate the high power diode-pumped solid-state laser at a continuous Q-switching mode and at a big number of transverse modes. The present invention also contemplates to reduce beam divergence and beam spot size and thus to increase power density of the laser on target tissue to improve the speed of tissue ablation. The present invention further contemplates to minimize power consumption such that external water-cooling or secondary cooling loop can be eliminated. The present invention even further contemplates to implement combined mechanisms to protect intracavity optics from power damage. Finally, the present invention contemplates hospitals and surgeon offices to use the high power diode-pumped laser for soft tissue ablation with standard electrical wall-plug outlet and elimination of inconvenient external water-cooling or secondary cooling loop.

Abstract: A method and system for providing ultrasound treatment to a deep tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. The invention delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, whereby eliminating the fat protrusions into the dermis. The invention can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.

Abstract: A method of laser processing of materials and specifically laser induced ablation processes for laser removal of material by impulsive heat deposition (IHD) by direct and specific excitation of short lived vibrations or phonons of the material in such a way as to not generate highly reactive and damaging ions through multiphoton absorption. The heat deposition and ensuing ablation is achieved faster than heat transfer to surrounding tissue by either acoustic or thermal expansion or thermal diffusion. The deposited laser energy is channeled into the ablation process to drive the most efficient ablation process possible with minimal damage to surrounding areas by either ionizing radiation or heat effects.

Abstract: Systems and methods for transforming biological materials utilizing ultrafast laser light. According to some embodiments, a method for transforming a biological material may include calculating an ablation profile for the biological material by comparing initial characteristics of the biological material to desired characteristics for the biological material, and applying an output of an ultrafast laser to the biological material to transform the biological material using the ablation profile in such a way that collateral damage to remaining biological material is reduced.

Abstract: Embodiments of the invention are directed to improved surgical procedures such as ophthalmic procedures that utilize overlaid visual representations of three-dimensional data or other data with direct or indirect visual images of a surgical region (e.g. the eye) to provide improved information to a surgeon to speed surgical procedures and/or to provide improved outcomes of those procedures. In some embodiments, ophthalmic procedures are combined cataract removal and astigmatism reduction procedures. In other embodiments the ophthalmic procedures are corneal refractive surgical procedures that reshape the cornea to reduce astigmatism or other aberrations. In some ophthalmic procedures the three-dimensional data is topography data associated with the anterior surface of the cornea. In some embodiments, the three-dimensional data may be enhanced or replaced with aberrometric data associated with the optical path of the eye.

Abstract: A stand-alone laser device that provides low level laser therapy using one or more laser sources. The laser sources are attached to one or more arms which can be positioned to cause the laser light to impinge on a desired area of a patient's body. A scanning apparatus is attached to the arms which comprise structures that cooperate to cause an optical element to be able to simultaneously rotate about a central axis and move in a linear motion along that axis to achieve any desired scan pattern. Laser light of different pulse widths, different beam shapes and different scan patterns can be applied externally to a patient's body. In the preferred embodiment, red light having a wavelength of about 635 nm is used to stimulate hair growth on a patient's scalp.

Abstract: The present invention provides a prophylactic light activated treatment method for subjects at risk of a plaque-mediated thrombotic event, such as acute coronary syndromes. In one embodiment, the subject receives a dose of photosensitizer sufficient to result in a concentration of photosensitizer in the neovascularization associated with atherosclerotic disease to permit effective photodynamic therapy. Light of a wavelength that excites the photosensitizer, but that does not to any significant extent penetrate to an adventitial layer of the blood vessel, is applied to the region of the blood vessel. The therapeutic light dose, which may be applied in sequential stages, is sufficient to cause closure of neovasculature leakage and lead to plaque stabilization and reduced adverse clinical outcomes. The present invention further provides light transmission devices and systems useful in carrying out the methods of the present invention.

Abstract: A handpiece for tissue treatment is provided. The handpiece has receiving means for receiving a first light beam, at least two components and selector device being movable between at least two positions, each position corresponding to a component. The selector device may be moved between the two positions, thereby positioning a selected component in a beam path of the first light beam. The selected component provide one or more functions, such as sensing, emitting a third light beam, emitting no light beam, and/or emitting a second light beam in response to the first light beam being incident on the selected component. The second or third light beam may, if present, be emitted towards a target area, or said light beam(s) may be deflected towards a target area. Furthermore, a method for tissue treatment using such a handpiece, and a selector device for use in such a handpiece is provided.

Abstract: In a device for material processing by laser radiation, including a source of laser radiation emitting pulsed laser radiation for interaction with the material; optics focusing the pulsed processing laser radiation to a center of interaction in the material and a scanning unit shifting the positions of the center of interaction within the material. Each processing laser pulse interacts with the material in a zone surrounding the center of interaction assigned to the laser pulse so that material is separated in the zones of interaction. A control unit controls the scanning unit and the source of laser radiation such that a cut surface is produced in the material by sequential arrangement of zones of interaction. The control unit controls the source of laser radiation and the scanning unit such that adjacent centers of interaction are located at a spatial distance a?10 ?m from each other.

Abstract: A laser treatment device and process with controlled cooling. The device contains a cooling element with high heat conduction properties, which is transparent to the laser beam. A surface of the cooling element is held in contact with the tissue being treated while at least one other surface of the cooling element is cooled by the evaporation of a cryogenic fluid. The cooling is coordinated with the application of the laser beam so as to control the temperatures of all affected layers of tissues. In a preferred embodiment useful for removal of wrinkles and spider veins, the cooling element is a sapphire plate. A cryogenic spray cools the top surface of the plate and the bottom surface of the plate is in contact with the skin. In preferred embodiments the wavelength of the laser beam is chosen so that absorption in targeted tissue is low enough so that substantial absorption occurs throughout the targeted tissue. In a preferred embodiment for treating large spider veins with diameters in the range of 1.