With Coolant Supply Patents (Class 606/22)
  • Patent number: 11033319
    Abstract: Disclosed is a cryotherapy device comprising at least one inflow channel, at least one outflow channel, control means for controlling the evacuation of expanded cryo-fluid from a body lumen, wherein the control means receive data from at least one sensor that gathers data regarding at least one parameter of the body lumen and wherein the cryotherapy device is introduced into the body lumen via an endoscope.
    Type: Grant
    Filed: November 22, 2015
    Date of Patent: June 15, 2021
    Assignee: Vesica E.K. Therapeutics Ltd.
    Inventor: Eyal Kochavi
  • Patent number: 11026737
    Abstract: Embodiments of the present invention relate to cryogenic systems and methods useful to cool objects, including living tissue, to freezing or cryogenic temperatures by placing the object in thermal communication with sub-cooled supercritical nitrogen.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 8, 2021
    Assignee: Endocare, Inc.
    Inventors: John G. Baust, John M. Baust, Anthony T. Robilotto
  • Patent number: 11020098
    Abstract: Cryogenic biopsy assemblies are described herein that comprise a tissue acquisition device and cryogenic probe. Also disclosed are systems containing such cryogenic biopsy assemblies and methods cryogenic biopsy that employ such cryogenic biopsy assemblies.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: June 1, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: William Abner, Allison Mary Day, Briana Moretti, John Allen Hingston, Amy Levasseur, Donald C. von Linden, Jr., Sujit Tatke, Paul Smith
  • Patent number: 10918433
    Abstract: An electrosurgical apparatus for generating a plasma discharge beam is provided. In one aspect, the electrosurgical apparatus includes a first fluid flow housing, a second fluid flow housing, and an electrode. A first gas is provided to the distal end of the first fluid flow housing, where the electrode is energized to ionize the first gas and generate a plasma discharge beam. A second gas is provided to the distal end of the second fluid flow housing, where the distal end of the second fluid flow housing injects the second gas into the plasma discharge beam. In another aspect, the electrosurgical apparatus includes a single fluid flow housing having an external electrode and an internal electrode. In another aspect, the electrosurgical apparatus includes a transformer assembly having a plurality of serially-connected transformers.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: February 16, 2021
    Assignee: Apyx Medical Corporation
    Inventors: Gregory A. Konesky, Claes Fredrik Jonsson
  • Patent number: 10869709
    Abstract: A cryosurgery system for application of medical-grade liquid nitrogen to a treatment area via a small, low pressure, open tipped catheter. The system includes a console, including a touch panel computer, a cryogen module, a suction module and an electronics module, and a disposable spray kit. Features include optional low cryogen flow setting to reduce the cryogen flow rate by 50%, improved cryogen flow consistency reducing pressure pulses and peaks, an integrated suction pump for improved consistency and self-checks, specified vent tube areas and corresponding maximum expected pressures during cryospray procedure; optional pressure sensing capability to monitor pressure during a treatment, and novel catheter designs of multilayer and flexible construction providing a variety of spray patterns.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: December 22, 2020
    Assignee: CSA Medical, Inc.
    Inventors: Ron Burr, Rafael Cordero, Marc Davidson, Wendelin Maners, Janel Petrilli
  • Patent number: 10675078
    Abstract: A system and kit for using a source of low-pressure refrigerant for a cryotherapy procedure and for subcooling a cryotherapy refrigerant. The system may generally include a fluid reservoir and a fluid flow path in thermal exchange with the fluid reservoir, the fluid flow path including a first thermal exchange device in thermal exchange with the fluid reservoir, a compressor in fluid communication with the first thermal exchange device, a condenser, a reversing valve located between the compressor and the condenser, a second thermal exchange device located between the reversing valve and the compressor, and an expansion valve located between the condenser and the thermal exchange device. The third thermal exchange device may be configured to be in fluid communication with the cryotherapy console and configured to place a secondary refrigerant within the first fluid flow path in thermal communication with a secondary refrigerant of the cryotherapy system.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: June 9, 2020
    Assignee: Medtronic CryoCath LP
    Inventors: Rachid Mahrouche, Eric Monger, Vladimir Tzonev
  • Patent number: 10398153
    Abstract: A liquid nitrogen dispenser for frozen treats comprises an anodized mount, an anodized cover attached onto the anodized mount, an inlet integrated into the anodized cover, an outlet integrated into the anodized cover, a dispensing tube, a primary flow valve mounted in between the anodized cover and the anodized mount and in fluid communication with the inlet and the outlet, a phase separator externally mounted to the anodized cover and in fluid communication with the outlet by the dispensing tube, an access hole traversing through the anodized cover, an annular gasket penetrating the access hole and peripherally pressed against the anodized cover and an insulating layer positioned around the primary flow valve, mounted across the anodized cover and pressed in between the anodized cover and the annular gasket.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: September 3, 2019
    Inventor: Miguel Angel Fernandez
  • Patent number: 10278565
    Abstract: An endoscope having a distal electrical feed-through, the endoscope including: an endoscope shaft having a distal objective unit comprising an electromagnetic actuator and a distal optical assembly that can be shifted in a longitudinal direction by actuation of the actuator, the endoscope shaft having a proximal unit having a proximal optical assembly arranged after the distal optical assembly in the direction of incident light, the objective unit is rotatable relative to the proximal unit about a longitudinal axis during assembly of the endoscope and is fixed rotationally relative to the proximal unit after assembly; and a cable for supplying current to the actuator, the cable being fed from the proximal unit to the objective unit, the cable having an excess length at a transition from the proximal unit to the objective unit, such excess length being at least half of the outer circumference of the objective unit.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: May 7, 2019
    Assignee: OLYMPUS WINTER & IBE GMBH
    Inventor: Martin Wieters
  • Patent number: 10238533
    Abstract: Peritoneal heat exchange provides the benefit of extremely rapid cooling of the patient's target organs such as the heart and brain as well as facilitating global patient body temperature reduction to therapeutically effective temperatures. The heat exchange medium of the present invention is a chilled gaseous fluid suspension of frozen ice particles.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: March 26, 2019
    Assignee: Qool Therapeutics, Inc.
    Inventor: Amir Belson
  • Patent number: 9956024
    Abstract: A system and method for providing greater control over the temperature of a thermal treatment element of a medical device, enabling an operator to extend a thawing period of a cryoablation procedure. The system may include a fluid flow path that bypasses a subcooler, giving the operator selective control over the temperature of refrigerant delivered to the treatment element and, therefore, treatment element temperature. Additionally or alternatively, the system may include a fluid delivery conduit that is in communication with a liquid refrigerant and a gaseous refrigerant. Adjustment of the ratio of liquid to gaseous refrigerant also offers control over the treatment element temperature. Additionally or alternatively, the system may include one or more valves and/or heating elements in the fluid delivery and recovery conduits to control the treatment element temperature.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: May 1, 2018
    Assignee: Medtronic CryoCath LP
    Inventors: Rachid Mahrouche, Dan Wittenberger
  • Patent number: 9848933
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: December 26, 2017
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, Ric Cote, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9821171
    Abstract: The present invention relates to an optical apparatus for skin treatment and to a method for controlling the optical apparatus. The optical apparatus includes a radiating part for radiating light generated in a light-generation part onto a target position of the skin, a cooling part for spraying cooling gas onto the target position to cool the surface of the skin, and a control part for controlling operations of the radiating part and cooling part. The control part controls the radiating part and the cooling part such that the radiating part radiates a first light onto the target position, the cooling part sprays the cooling gas onto the target position, and then the radiating part radiates a second light onto the target position.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: November 21, 2017
    Assignee: Lutronic Corporation
    Inventor: Kwang Chon Ko
  • Patent number: 9820796
    Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: November 21, 2017
    Assignee: Channel Medsystems, Inc.
    Inventors: Daniel R. Burnett, Ric Cote, William W. Malecki, Brian M. Neil, David Beaulieu, Benjamin D. Voiles
  • Patent number: 9808301
    Abstract: A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: November 7, 2017
    Assignee: Medtronic CryoCath LP
    Inventors: Marwan Abboud, Rachid Mahrouche, Chadi Harmouche, Teresa Ann Mihalik, Giles Desrochers
  • Patent number: 9662097
    Abstract: A method of expanding a narrowed region inside a living body involves positioning a liquid introducer in the narrowed region in the living body and introducing liquid into the narrowed region by way of the liquid introducer. The liquid applies an outwardly directed force on the narrowed region to expand the narrowed region. The narrowed region includes the renal pelvis, the entrance to the lower calix, the ureter, etc.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: May 30, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kei Honda
  • Patent number: 9649143
    Abstract: An electrosurgical system to generate a pulsed plasma stream and method thereof are provided. The system includes an electrosurgical generator coupled to an electrical power source to supply power for the electrosurgical system; a plasma generator including a noble gas conduit and an electrode disposed with the noble gas conduit, the electrode operatively coupled to the electrosurgical generator to selectively receive electrical energy therefrom such that the electrode at least partially ionizes a carrier gas feed to the noble gas conduit to create a plasma discharge; and a flow controller coupled to the noble gas conduit to pulse the flow of the carrier gas from a gas source to the noble gas conduit such that when the electrode is energized pulses of plasma discharge are generated at the surgical site.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: May 16, 2017
    Assignee: BOVIE MEDICAL CORPORATION
    Inventors: Gregory A. Konesky, Borislav S. Simeonov
  • Patent number: 9636127
    Abstract: A method of moving a device toward a target site in a living body involves introducing an endoscope into the living body, wherein the endoscope has an instrument channel, with the device located at the distal end of the endoscope, and an elongated shaft connected to the device and positioned in the instrument channel. The method includes moving the endoscope and the device within the living body toward the target site, changing the shape of the elongated shaft while moving the device in the living body, and moving the device within the living body while the device is in the second orientation to position the device in the second orientation at the target site.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: May 2, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kei Honda
  • Patent number: 9636123
    Abstract: A calculus removing device includes an elongated member and a retrieval part fixed to the elongated member. A discharge force is produced in a lumen in the elongated member to discharge fluid in the lumen into the renal pelvis, and a suction force is produced in the lumen to draw fluid into the lumen from the renal pelvis. An outlet communicates with the lumen, and fluid in the lumen is discharged into the renal pelvis through the outlet in the presence of the discharge force. An inlet communicates with the lumen, and fluid in the renal pelvis is drawn into the lumen through the inlet in the presence of the suction force. The retrieval part includes an interior that communicates with the lumen and the renal pelvis, and the interior is configured to receive the calculus in the renal pelvis in the presence of the suction force.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: May 2, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kei Honda, Makoto Narita
  • Patent number: 9615842
    Abstract: A method of retrieving calculus in a renal pelvis of a living body involves positioning an enclosure in the renal pelvis, creating convection in the renal pelvis by introducing liquid into the renal pelvis from outside the living body to lift the calculus from a surface of the renal pelvis, retrieving the calculus in the renal pelvis by creating a vacuum in the enclosure while the enclosure is located in the renal pelvis so that the calculus are drawn into the enclosure, wherein the vacuum also draws the liquid into the enclosure, and withdrawing the enclosure from the renal pelvis while the calculus is in the enclosure.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: April 11, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kei Honda, Makoto Narita
  • Patent number: 9610087
    Abstract: A method of removing/retrieving calculus in a ureteral lumen involves moving a ureteral plug part along the ureter lumen to position the ureteral plug part between the calculus and the kidney. The method additionally includes occluding the ureteral lumen at a location at which the ureteral plug part is located, and introducing fluid into the ureter lumen at a point between the location of the occlusion and the calculus so that the fluid washes the calculus toward the bladder. Another aspect involves a method in which an drainage tube is positioned in the ureteral lumen so that a ureteral plug part and an irrigation port are positioned distally of the calculus while an operation part of the drainage tube is positioned proximally of the calculus. The method includes occluding the ureteral lumen, washing the ureteral lumen, and releasing the occlusion and uncoupling the operation part from the ureteral plug.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: April 4, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Kei Honda, Wataru Karino
  • Patent number: 9561065
    Abstract: A surgical instrument kit comprising: (a) a robotic arm comprising a first jaw including a first bipolar electrode and a second jaw including a second bipolar electrode, wherein at least one of first jaw and second jaw is repositionable with respect to the other jaw; (b) a first surgical tool head including a first electrical load in electrical communication with a first pair of electrical terminals, the first surgical tool head adapted to be removably coupled to the robotic arm; and, (c) a second surgical tool head including a second electrical load in electrical communication with a second pair of electrical terminals, the second surgical tool head adapted to be removably coupled to the robotic arm, where the first pair of electrical terminals of the first surgical tool head are adapted to engage the first bipolar electrode and the second bipolar electrode to establish electrical communication between the first bipolar electrode and a first of the first pair of electrical terminals and between the second bi
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: February 7, 2017
    Assignee: AtriCure, Inc.
    Inventors: Salvatore Privitera, Matthew Monti, William J. Abner, Adam Harp, Jeffrey W. Stone
  • Patent number: 9539014
    Abstract: A calculus retrieving device for retrieving calculus in a renal pelvis includes an elongated member positionable in and movable along a ureter, and having a lumen opening at the distal end of the elongated member. A tubular member is movably positioned inside the elongated member and includes a lumen which opens to a discharge nozzle at a distal end of the tubular member. A space exists between the elongated member and the tubular member to receive a first fluid, and an expandable renal cover part fixed to the elongated member is positionable in the renal pelvis. The renal cover part interior communicates with the space so that the first fluid flows into the renal cover part to expand the renal cover part into covering relation to one part of the renal pelvis while another part of the renal pelvis containing the calculus is not covered by the renal cover part.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: January 10, 2017
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kei Honda
  • Patent number: 9517080
    Abstract: A method of removing/retrieving calculus in a renal pelvis includes moving a renal cover part along a ureter toward the renal pelvis, introducing the renal cover part into the renal pelvis, positioning the renal cover part in the renal pelvis so that the renal cover part covers one part of the renal pelvis, while an other part of the renal pelvis is not covered by the renal cover part, introducing fluid into the other part of the renal pelvis, while the one part of the renal pelvis is covered by the renal cover part, to cause the calculus in the other part of the renal pelvis to be washed-out of the renal pelvis, and moving the renal cover part out of the renal pelvis and into the ureter.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: December 13, 2016
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kei Honda
  • Patent number: 9326808
    Abstract: The system for providing computer guided ablation of tissue of a patient includes an ablative surgical computer system and a set of surgical devices. The ablative surgical computer system includes a guidance module for providing a treatment guidance plan to an operator; and, a treatment module for acquiring and processing surgical device output data, for optimally controlling treatment parameters and providing feedback information to the operator based on the treatment guidance plan. The set of surgical devices includes at least one ablative device for providing ablation of the treatment region based on the treatment parameters and operator input; and, at least one temperature sensing device for acquiring temperature data from the treatment region and providing a temperature sensing device output signal. The temperature sensing device output signal is a portion of the surgical device output data.
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: May 3, 2016
    Assignee: ENOCARE, Inc.
    Inventors: Sanford D. Damasco, Thach Duong, Jawahar M. Ali, Paul W. Mikus, Jay J. Eum
  • Patent number: 9254162
    Abstract: Medical devices, systems, and methods optionally treat dermatological and/or cosmetic defects, and/or a wide range of additional target tissues. Embodiments apply cooling with at least one small, tissue-penetrating probe, the probe often comprising a needle having a size suitable for inserting through an exposed surface of the skin of a patient without leaving a visible scar. Treatment may be applied along most or all of the insertable length of an elongate needle, optionally by introducing cryogenic cooling fluid into the needle lumen through a small, tightly-toleranced lumen of a fused silica fluid supply tube, with the supply tube lumen often metering the cooling fluid. Treatment temperature and/or time control may be enhanced using a simple pressure relief valve coupled to the needle lumen via a limited total exhaust volume space.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: February 9, 2016
    Assignee: MyoScience, Inc.
    Inventors: Keith Burger, Ronald Williams, Lisa Elkins
  • Patent number: 9144449
    Abstract: A cryosurgery system for application of medical-grade liquid nitrogen to a treatment area via a small, low pressure, open tipped catheter. The system includes a console, including a touch panel computer, a cryogen module, a suction module and an electronics module, and a disposable spray kit. Features include optional low cryogen flow setting to reduce the cryogen flow rate by 50%, improved cryogen flow consistency reducing pressure pulses and peaks, an integrated suction pump for improved consistency and self-checks, specified vent tube areas and corresponding maximum expected pressures during cryospray procedure; optional pressure sensing capability to monitor pressure during a treatment, and novel catheter designs of multilayer and flexible construction providing a variety of spray patterns.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: September 29, 2015
    Assignee: CSA Medical, Inc.
    Inventors: Ron Burr, Rafael Cordero, Marc Davidson, Wendelin Cherise Maners, Janel Petrilli
  • Patent number: 9089316
    Abstract: A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues, particularly as utilized for the ablation of cardiac tissue in the treatment of atrial fibrillation. The device is a closed or semi-closed system in which the liquid cryogen is nitrogen contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state, specifically supercritical nitrogen, and may be utilized in any rapid cooling systems. As designed, the device also integrates endocardial catheters and epicardial probes.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: July 28, 2015
    Assignee: Endocare, Inc.
    Inventors: John M Baust, John G. Baust, Roy E. Cheeks, Melissa K Dobson, Anthony T. Robilotto, Kristi K. Snyder, Robert G. Van Buskirk
  • Patent number: 9084592
    Abstract: A focal ablation assembly, used with an endoscope comprising an endoscopic tube, comprises a cryogenic catheter, a balloon and a reinforcing element. The cryogenic catheter is placeable within the endoscopic tube channel and has a distal end placeable at the distal end of the endoscopic tube. The balloon is mountable to the catheter distal end and extends distally of both of the distal ends. The reinforcing element at least partially defines the shape of the balloon in the expanded state. The balloon defines a balloon volume when expanded and has a thermally conductive therapeutic region which provides effectively no thermal insulation. In some examples the focal ablation assembly comprises a delivery catheter extending along the channel with a distal portion fluidly coupled to the balloon interior, whereby refrigerant can be introduced into the balloon interior and towards the therapeutic region by the delivery catheter.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: July 21, 2015
    Assignee: C2 THERAPEUTICS, INC.
    Inventors: Patrick P. Wu, Cesar A. Ico, Richard S. Williams
  • Patent number: 9050075
    Abstract: A cryosurgical instrument including: a shaft having a closed distal end defining an expansion chamber and an open proximal end adapted and configured to receive an inflow of cryogen and to exhaust a flow of expanded cryogen; and a heat exchanger. The heat exchanger includes: a plurality of cryogen delivery tubes that spiral around a longitudinal axis thereof; and a diffuser having a plurality of branches, each of the branches supplying received cryogen to a respective one of the delivery tubes. The cryogen delivery tubes, where they spiral, are spaced from each other and in fluid tight contact with the inner surface of the shaft so as to form spiraling cryogen exhaust pathways that extend along a portion of a length of the cryosurgical instrument from the distal end of the shaft.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: June 9, 2015
    Assignee: ICECURE MEDICAL LTD.
    Inventors: Nir Berzak, Ron Hilleli
  • Patent number: 9044212
    Abstract: A device and method for safely securing a multilumen device to a tissue, organ or solid tumor within the body of a human during a diagnostic or therapeutic procedure is described. The device is capable of securing the tumor by touching or piercing its surface and providing a coolant to the distal tip. Cooling the tip forms a cryogenically induced region that tightly binds the tip to the tumor, temporarily sealing the entry-track of the instrument. The device further provides at least one injecting/aspirating lumen that can dispense or aspirate a fluid within the tumor, and an outer sheath or guide. Such construction allows injecting part or whole volume of the tumor while the cryogenically induced bond prevents back-flow of the injected substances through the entry-track.
    Type: Grant
    Filed: April 22, 2010
    Date of Patent: June 2, 2015
    Assignee: Nuvue Therapeutics, Inc.
    Inventor: Patrick LePivert
  • Publication number: 20150148791
    Abstract: Cryotherapeutic systems and cryotherapeutic-system components configured for renal neuromodulation are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment of the present technology can include a console having a cartridge housing, a cartridge connector adjacent to the cartridge housing, and a supply passage fluidly connected to the cartridge connector. The console can further include a supply valve along the supply passage and a control assembly including a supply-valve actuator and a user interface. The supply-valve actuator can be operably connected to the supply valve, and the control assembly can be configured to signal the supply-valve actuator to open the supply valve in response to a signal from the user interface.
    Type: Application
    Filed: November 2, 2012
    Publication date: May 28, 2015
    Applicant: Medtronic Ardian Luxemborug S.a.r.l.
    Inventors: Matthew Birdsall, Gabriel Brennan, Anthony Bertrand, Brian Donlon, Kara Harrington, Brian Kelly, Micheal Moriarty, Stephen Nash, Elger Oberwelz, Fiachra Sweeney, Roman Turovskiy
  • Patent number: 9039688
    Abstract: A method for cryogenically treating a target tissue comprises providing a cryogenic device having one or more tissue penetrating needle probes, and advancing the one or more tissue penetrating needle probes through skin disposed above the target tissue into the target tissue. The target tissue comprises a motor nerve. The method also includes cooling the target tissue with the one or more tissue penetrating needle probes, and temporarily disrupting signal conduction from the motor nerve thereby preventing contraction of a muscle operably coupled to the motor nerve. This reduces or eliminates hyperdynamic wrinkles of a patient's face.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: May 26, 2015
    Assignee: MyoScience, Inc.
    Inventors: Francis R. Palmer, III, Michael Hsu, Kristine Tatsutani
  • Publication number: 20150141975
    Abstract: Embodiments disclosed herein are directed to fluid spraying apparatuses, and related systems and methods. The disclosed fluid spraying apparatuses may be used, for example, to spray a medically suitable fluid on a target region of a subject, such as for treating or removing tissue of the subject. In an embodiment, a fluid spraying apparatus includes a spray mechanism including at least one reservoir, and a spraying device operably coupled to the at least one reservoir which has an adjustable spray nozzle. The fluid spraying apparatus includes a distance sensor configured to sense information at least related to a distance to a target region of a subject and output one or more signals encoding the information, and control electrical circuitry operably coupled to the spray mechanism and the distance sensor. The control electrical circuitry is configured to activate the spray mechanism responsive to receiving the one or more signals.
    Type: Application
    Filed: January 29, 2015
    Publication date: May 21, 2015
    Inventors: Mahalaxmi Gita Bangera, Roderick A. Hyde, Jordin T. Kare, Eric C. Leuthardt, Lowell L. Wood, JR.
  • Patent number: 9011420
    Abstract: A method of operating a medical system, including coupling a medical system to an outlet of a fluid distribution network having a plurality of fluid outlets in a patient treatment center; delivering fluid from the outlet to the medical system; compressing the delivered fluid with the medical system; decreasing the moisture content of the delivered fluid with the medical system; cooling the fluid with the medical system; delivering the fluid from the medical system to a medical device; and removing the fluid from medical device with the medical system.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: April 21, 2015
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 8998888
    Abstract: A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is a closed or semi-closed system in which the liquid cryogen is contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state and may be utilized in any rapid cooling systems. As designed, the device comprises a number of parts including a vacuum insulated outer dewar, submersible cryogen pump, baffled linear heat exchanger, multiple pressurization cartridges, a return chamber, and a series of valves to control the flow of the liquid cryogen. The cryogenic medical device promotes the subcooling to any external cryogenic instrument.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: April 7, 2015
    Assignee: Endocare, Inc.
    Inventors: John M. Baust, John G. Baust, Roy Cheeks, Anthony Robilotto, Kristi Snyder
  • Publication number: 20150094702
    Abstract: Cryogenic device for carrying out cryotherapy on the entire body of a patient, the cryogenic device includes a treatment cabin for taking up a patient, the treatment cabin having closed walls, a closed roof and a door for entering the treatment cabin; a cold treatment gas preparation and distribution system for preparing a cold gas mixture and introducing it into the treatment cabin; and a control system for controlling the introduction of cold treatment gas from the cold treatment gas preparation and distribution system into the treatment cabin, in which the treatment cabin further includes a breathing window for allowing a patient located inside the treatment cabin to breath air from outside of the treatment cabin, the breathing window including sealing means for allowing a tight contact between the breathing window and the face of the patient.
    Type: Application
    Filed: May 29, 2013
    Publication date: April 2, 2015
    Inventor: Vladimir SHUPPO
  • Patent number: 8951246
    Abstract: A cryosurgical device, with a control for the supply and/or removal of a coolant gas to a cryoprobe via a return flow or a supply flow. The device has at least one socket for the attachment of a rigid cryoprobe and a flexible cryoprobe. The socket and the plugs of the cryoprobes each form probe couplings. The configuration of the cryosurgical device allows both rigid and flexible cryoprobes to be automatically connected to the appropriate return flow conduit, independently of the level of knowledge of operating personnel.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: February 10, 2015
    Assignee: Erbe Elektromedizin GmbH
    Inventor: Franz Geiselhart
  • Patent number: 8945106
    Abstract: A cryogenic probe design is provided containing, for example, an inner coil injection tube with a continuous flow of circulating liquid and an outer jacket enclosing the inner coil injection tube. A transducer may monitor parameters in the region between the inner coil injection tube and the outer jacket. An outer jacket serves to prevent gas leakage. One or more embodiments of a probe design provide continuous flow for example via a continuous and controlled path from inlet to outlet and an expanded thermally transmissive region. Expanding a thermally transmissive region of the cooling zone may be provided, for example, in one or more embodiments of injection tube designs.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: February 3, 2015
    Inventors: Steve Arless, Daniel Nahon, Domenic Santoianni
  • Publication number: 20150018810
    Abstract: A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is a closed or semi-closed system in which the liquid cryogen is contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state and may be utilized in any rapid cooling systems. As designed, the device comprises a number of parts including a vacuum insulated outer dewar, submersible cryogen pump, baffled linear heat exchanger, multiple pressurization cartridges, a return chamber, and a series of valves to control the flow of the liquid cryogen interconnected with cryotreatment devices including cryoprobes and catheters. The cryogenic medical device promotes subcooling to the tips of various external cryogenic instrument configurations.
    Type: Application
    Filed: July 21, 2014
    Publication date: January 15, 2015
    Inventors: John M. Baust, Roy E. Cheeks, John G. Baust, Anthony Robilotto, Kristi K. Snyder
  • Patent number: 8906005
    Abstract: A cryo-surgical system may comprise a container containing a refrigerant, a delivery tube having a first end configured to be in flow communication with the container and a second end opposite the first end. The system may further include a plurality of flexible finger portions disposed proximate a second end of the delivery tube opposite the first end, an applicator bud having a body portion disposed within the plurality of flexible finger portions and a contact surface extending from the plurality of flexible finger portions. An adjustment ring may be disposed along the delivery tube adjacent to the plurality of flexible finger portions. The contact surface of the bud may be changeable by adjustment of the adjustment ring.
    Type: Grant
    Filed: June 11, 2009
    Date of Patent: December 9, 2014
    Assignee: Orasure Technologies, Inc.
    Inventor: Philip Michael Formica
  • Patent number: 8900222
    Abstract: A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: December 2, 2014
    Assignee: Medtronic Cryocath LP
    Inventors: Marwan Abboud, Rachid Mahrouche, Chadi Harmouche, Teresa Ann Mihalik, Giles Desrochers
  • Patent number: 8882755
    Abstract: A novel medical probe assembly, system, and methods for the use thereof to treat tissue are described. The system optionally comprises an energy source, two probe assemblies, and one or more cooling devices to provide cooling to at least one of the probe assemblies. The probe assemblies may be configured in a bipolar mode, whereby current flows preferentially between the probe assemblies. The probe assemblies and system described herein are particularly useful to deliver radio frequency energy to a patient's body. RF energy delivery may be used for various applications, including the treatment of pain, tumor ablation and cardiac ablation.
    Type: Grant
    Filed: April 14, 2005
    Date of Patent: November 11, 2014
    Assignee: Kimberly-Clark Inc.
    Inventors: Mark Leung, Krishan Shah, Laura Conquergood, Subashini Chandran
  • Patent number: 8845628
    Abstract: A cryoablation system includes thermally insulated containers for holding liquid refrigerant. The containers are placed in a docking station that charges the containers with a liquid refrigerant at a cryogenic temperature suitable for carrying out a surgical procedure. The charged containers are detachably connectable with an inlet line of a cryoablation probe. When the cryoprobe is activated, the chilled liquid refrigerant is transported from a delivery container, through the cryoprobe, and to a recovery container. The recovery container is preferably identical in design to the delivery container. The refilled recovery container is then placed in the docking station to charge. In another embodiment, a cartridge includes a delivery container and recovery container combined as a single unit. Methods are also described.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: September 30, 2014
    Assignee: CryoMedix, LLC
    Inventors: Alexei Babkin, Peter Littrup, William Nydam, Barron Nydam
  • Patent number: 8834416
    Abstract: Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: September 16, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Ronald A. Sahatjian, Arthur Madenjian, William R. Little
  • Publication number: 20140243808
    Abstract: The present disclosure relates to a thermal ablation probe device that integrates deployable sensors with a freezing probe or heating probe for use in ablating tissues. The ablation probe includes a longitudinal body including a thermal ablation energy source which may be, e.g., a cryosource or a heat source. The longitudinal body has a proximal end and a distal end terminating at a probe tip; and at least one deployable assembly disposed within the longitudinal body. The deployable assembly includes a flexible and substantially rigid deployment member, and at least one sensor affixed to a distal end of the deployment member. The ablation probe further includes a control mechanism for controlling deployment and retraction of the deployable assembly.
    Type: Application
    Filed: February 26, 2014
    Publication date: August 28, 2014
    Applicant: CPSI HOLDINGS LLC
    Inventors: Marie Molnar-Hammond, John M. Baust
  • Publication number: 20140207131
    Abstract: A method for purging a cryotreatment system, in particular, for clearing moisture and thus preventing ice blockages within a fluid flow path that may be formed when moisture pockets within the fluid flow path of the system are encountered by a first injection of refrigerant at the beginning of a cryotreatment procedure. The method may include injecting refrigerant from a refrigerant source into a fluid delivery conduit at a preselected pressure for a first period of time, the refrigerant flowing from the fluid delivery conduit through a fluid injection element and into a fluid recovery conduit, and evacuating refrigerant from the fluid recovery conduit by vacuum pressure generated by the vacuum pump for a second period of time. This method may be repeated for a plurality of cycles.
    Type: Application
    Filed: January 23, 2013
    Publication date: July 24, 2014
    Applicant: MEDTRONIC CRYOCATH LP
    Inventors: Chadi HARMOUCHE, Rachid MAHROUCHE, Eric MONGER, Bertin SIMÉON, Vladimir TZONEV
  • Patent number: 8784409
    Abstract: A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is a closed or semi-closed system in which the liquid cryogen is contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state and may be utilized in any rapid cooling systems. As designed, the device comprises a number of parts including a vacuum insulated outer dewar, submersible cryogen pump, baffled linear heat exchanger, multiple pressurization cartridges, a return chamber, and a series of valves to control the flow of the liquid cryogen interconnected with cryotreatment devices including cryoprobes and catheters. The cryogenic medical device promotes subcooling to the tips of various external cryogenic instrument configurations.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: July 22, 2014
    Assignee: Endocare, Inc.
    Inventors: Anthony Robilotto, Kristi K. Snyder, John G Baust, John M. Buast, Roy E. Cheeks
  • Patent number: 8764740
    Abstract: Systems, apparatus and methods for dispersing a coolant along different portions of a supply tube of a cryo-ablation device which may be in the form of a linear ablation device or catheter probe or a balloon catheter. A supply tube includes multiple tubes that are in fluid communication with an inner space of a transmissive region or an inner space of an inflatable balloon. The tubes are coaxially arranged and extend to different lengths or to different locations such that the coolant is dispersed from different tubes at different axial locations. Annular apertures are defined by pairs of tubes and have different sizes. The tubes and arrangement thereof are structured to provide uniform or substantially uniform coolant distribution to provide uniform or substantially uniform cryo-ablation of surrounding tissue.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: July 1, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: James R. Watson
  • Patent number: 8747396
    Abstract: A cryosurgical probe assembly that includes a gas delivery assembly, including a stem and a fluid conduit subassembly bonded to the stem. The fluid conduit subassembly delivers and returns cooling fluid used for cryogenic cooling. The fluid conduit subassembly, comprises a shaft for providing a heat exchange surface for cryogenic ablation; a housing securely connected to said shaft; and, an insulation element slideably engaged with an inner surface of the shaft and slideably engaged with the stem. The cryosurgical probe assembly includes an adjustable sliding apparatus that includes a slider assembly securely attached to said insulation tube for slideably guiding the insulation tube along said shaft; and, a button assembly operatively connected to the slider assembly for allowing a user to actuate the slider assembly to provide a desired adjustment of the insulation tube relative to the shaft. A handle assembly is positioned about the housing.
    Type: Grant
    Filed: October 18, 2009
    Date of Patent: June 10, 2014
    Assignee: Endocare, Inc.
    Inventors: Thach Duong, Jay J. Eum
  • Patent number: 8740892
    Abstract: An expandable, flexible multi-tubular cryoprobe operational with a near critical cryogenic working fluid. The inlet fluid transfer micro-tubes utilized are formed of material that maintains flexibility in a full range of temperatures from ?200° C. to ambient temperature. During operation, the cryoprobe is mechanically actuated to provide radial expansion of the inlet fluid transfer micro-tubes. Thus, enhanced thermal contact with target biological tissue to be treated is provided.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: June 3, 2014
    Assignee: Endocare, Inc.
    Inventors: Alexei V. Babkin, Anatoly I. Efremov, Jay J. Eum