Abstract: A method of treating a patient is described herein. The method can include the steps of identifying a target that contains biological tissue and directing one or more pulses of electromagnetic radiation at the target. The pulses of electromagnetic radiation can cause a temperature increase per unit of time in the biological tissue. Additionally, the temperature increase per unit of time can cause the change in the cell function in the biological tissue and can be within a range of approximately one degree Celsius per second to approximately one degree Celsius per microsecond.

Abstract: A medical apparatus includes a first clamp portion; a pivot shaft; a second clamp portion rotatable around the pivot shaft, and movable between an opened position in which the second clamp portion is distant from the first clamp portion, and a closed position in which the second clamp portion is adjacent to the first clamp portion; and an electrode member provided on the second clamp portion, and opposed to the first clamp portion, the electrode member forming a clearance in cooperation with the first clamp portion in the closed position, the clearance in a second position distant from the pivot shaft being smaller than the clearance in a first position adjacent to the pivot shaft, to adjust holding pressure.

Abstract: Tissue ablation devices and methods including needle injectors that deliver flowable thermal treatment media into an interface with tissue and that can provide a single dose of ablative energy.

Abstract: An inventive system and method for touch free operation of an ablation workstation is presented. The system can comprise a depth sensor for detecting a movement, motion software to receive the detected movement from the depth sensor, deduce a gesture based on the detected movement, and filter the gesture to accept an applicable gesture, and client software to receive the applicable gesture at a client computer in an ablation workstation for performing a task in accordance with client logic based on the applicable gesture. The system can also comprise hardware for making the detected movement an applicable gesture. The system can also comprise voice recognition providing voice input for enabling the client to perform the task based on the voice input in conjunction with the applicable gesture. The applicable gesture can be a movement authorized using facial recognition.

Abstract: Example adjustable electrodes are described. One example adjustable electrode includes two or more contacts configured to selectively deliver high frequency alternating current (HFAC) to a nerve in an amount sufficient to produce an HFAC nerve conduction block in the nerve. The example adjustable electrode may also include a logic configured to selectively control which of the two or more contacts deliver HFAC to the nerve to control whether the nerve electrode is in a first (e.g., onset response mitigating) configuration or in a second (e.g., HFAC nerve conduction block maintenance) configuration. The electrode may be used in applications including, but not limited to, nerve block applications, and nerve stimulation applications. The electrode may be adjusted by changing attributes including, but not limited to, the number, length, orientation, distance between, surface area, and distance from a nerve of contacts to be used to deliver the HFAC.

Abstract: Apparatus comprising an ultrasound ablation system, which comprises a reflection-facilitation element, configured to be placed at an extramyocardial site of a subject, and to provide an extramyocardial reflective region; and an ultrasound tool, which comprises at least one ultrasound transducer configured to be positioned within a heart chamber of the subject. The ultrasound transducer is configured to ablate myocardial tissue by applying ultrasound energy to the myocardial tissue such that at least a portion of the transmitted energy is reflected by the reflective region onto the myocardial tissue. Other embodiments are also described.

Abstract: A treatment instrument includes: a proximal side probe transmits ultrasonic vibration from its proximal end to its distal end; a distal side probe configured to transmit the ultrasonic vibration from its proximal end to a treatment portion at its distal end; and a holding portion which holds a state where the proximal end of the distal side probe is into collision with the distal end of the proximal side probe, and a state where vibration is transmittable from the proximal end of the proximal side probe to the distal end of the distal side probe.

Abstract: A method and programmable computer system calculates and displays the regions where the temperature can be reliably measured in a thermal therapy procedure. The clinician or automated control system then can make an informed decision to treat these regions or plan a treatment to avoid them based on the sensitivity of surrounding structures to unintended heating.

Abstract: Methods, systems and devices for applying energy to tissue, and more particularly relates to a system for ablating or modifying structures in a body with systems and methods that generate a flow of vapor at a controlled flow rate for applying energy to the body structure.

Abstract: A method for mapping a 3D surface that contains a volume in space, the method including: acquiring 3D vertices representing the surface, and defining in the space a first plane cutting the volume and a second parallel plane, external to the volume, thereby partitioning the vertices into a first set not between the two planes and a second set located between the two planes. The method further includes projecting the first set vertices onto the first plane so as to generate first projected points therein, and projecting the second set vertices onto the first plane while translating these vertices in respective directions parallel to the second plane by respective translations responsive to respective distances of the second vertices from the first plane, thereby generating second projected points in the first plane. The first and second projected points are displayed as a 2D representation of the surface on a screen.

Abstract: A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.

Abstract: An inventive system and method for touch free operation of an ablation workstation is presented. The system can comprise a depth sensor for detecting a movement, motion software to receive the detected movement from the depth sensor, deduce a gesture based on the detected movement, and filter the gesture to accept an applicable gesture, and client software to receive the applicable gesture at a client computer in an ablation workstation for performing a task in accordance with client logic based on the applicable gesture. The system can also comprise hardware for making the detected movement an applicable gesture. The system can also comprise voice recognition providing voice input for enabling the client to perform the task based on the voice input in conjunction with the applicable gesture. The applicable gesture can be a movement authorized using facial recognition.

Abstract: An ablation catheter arrangement includes an ablation generator, a rinsing liquid source for providing a liquid for rinsing the treatment area in which ablation is performed, and an ablation catheter connectable to the ablation generator and to the rinsing liquid source. The ablation catheter has an ablation area, at least one rinsing opening, and a rinsing bath for supplying rinsing liquid to the treatment area. A blood pressure measurement device detects the intracardiac blood pressure over the liquid column of the rinsing liquid, and communicates with the rinsing channel of the ablation catheter by fluid connection.

Abstract: A tissue grasping device includes a longitudinal axis member; an actuating member provided at a distal end portion of the longitudinal axis member; a wire member elongated to an outside of the actuating member and being curved in a loop shape; a through hole formed in a distal end surface of the actuating member and holding a first end side of the wire member such that the first end side of the wire member is capable of moving with respect to the actuating member; and a direction restriction portion provided at a side surface of the actuating member and fixing a second end portion of the wire member to the actuating member such that an elongated direction of a second end side of the wire member is coincide with a direction intersecting a side surface of the actuating member.

Abstract: An energy-delivery device suitable for delivery of energy to tissue includes an antenna assembly, a chamber defined about the antenna assembly, and a cable having a proximal end suitable for connection to an electrosurgical energy source. The energy-delivery device also includes a flexible, fluid-cooled shaft coupled in fluid communication with the chamber. The flexible, fluid-cooled shaft is configured to contain a length of the cable therein and adapted to remove heat along the length of the cable during delivery of energy to the antenna assembly.

Abstract: The present devices and methods relate generally to vacuum or suction powered medical devices and methods for cutting, resecting, excising, morcellating and/or evacuating tissue from various regions of a patient's body. In certain variations, the devices may produce a rotational motion by converting a linear reciprocating motion to a rotational motion, causing a cutting shaft or other tool to rotate to perform work on a tissue in various regions of the body.

Abstract: In the treatment of a tumor (126) with radiation therapy (122) is enhanced by a weak magnetic field (130), the field strength time sequence of exposure and shape and contour of the magnetic field are varied to achieve desired results. In one separate aspect, exposure to a magnetic field (130) is continued after exposure to a free radical-creating therapy is ceased or diminished, thereby increasing the lifetimes of free radicals that have already been created. In another preferred embodiment a magnetic field (13) is strategically placed to avoid extending the lives of free radicals in tissue through which a free radical-creating beam must pass, to reach a tumor. This application discloses quantitative parameters for field strength and exposure time to create concentrations and reactivity of free radicals, including long-lived free radicals and discloses the use of shaped, contoured, and designed electromagnetic fields. A treatment planning station (200) is also disclosed.

Abstract: A microwave ablation system includes a power source. A microwave antenna is adapted to connect to the power source via a coaxial cable that includes inner and outer conductors having a compressible dielectric operably disposed therebetween. The inner conductor in operative communication with a radiating section associated with the microwave antenna. The outer conductor includes a distal end transitionable with respect to each of the inner conductor, compressible dielectric and radiating section from an initial condition wherein the distal end has a first diameter to a subsequent condition wherein the distal end has second diameter. Transition of the distal end from the initial condition to the subsequent condition enhances the delivery of microwave energy from the power source to the inner conductor and radiating section such that a desired effect to tissue is achieved.

Abstract: A plasma treatment equipment includes: a plasma starting and stabilizing unit (A) having an insulating material such as a dielectric material having an elongated hole connecting to a plasma ejection portion, a triggering and discharge-stabilizing electrode, and an intense electric field electrode mounted thereon; and a plasma generating unit (B) including the insulating material having the elongated hole and a plasma generating electrode configured to perform main plasma generation at the time of operation, wherein the triggering and discharge-stabilizing electrode, the intense electric field electrode, and the plasma generating electrode are provided in such a manner that all the electrodes are not exposed and covered with the dielectric material for the entire space of one or more of the elongated hole which allows passage of gas from the upstream, starting of the plasma and generation of the plasma, and ejection of the plasma jet.

Abstract: A nozzle for a plasma generator having a body defining a plasma generating chamber with a gas inlet at one end and a plasma outlet at the opposite end defining the flow direction from the inlet to the outlet. An inner electrode is positioned around an inner wall of the body and an outer earthed electrode is provided around an outer wall of the body. The inner electrode and the outer electrode overlap one another in the flow direction.

Abstract: A magnetic moxibustion device includes a moxibustion canister in which a moxa column (5) is hangs through a moxa column mounting base. The moxa column mounting base is mounted on the moxibustion canister in a detachable manner through a magnetic attraction structure. A magnet guiding needle (3) is further disposed in the moxa column mounting base, which passed through the moxa column (5). The magnetic field of the magnetic attraction structure is guided out of the moxibustion canister through the needle (3) and applied to the human body moxibustion application position, so as to perform the moxibustion therapy and the magnet therapy at the same time. A side wall of the moxibustion canister is provided with several air inlets (7) and air outlets (11), so the combustion speed of the moxa column (5) can be adjusted through the size of the air outlets, thereby adjusting the temperature and time of the moxibustion.

Abstract: To improve the overall navigation process for minimally invasive repair of heart valve leaflets, an augmented reality technique capable of providing a robust three-dimensional context for transesophogeal echocardiography data has been developed. In the context of various embodiment of the invention, augmented reality essentially refers to a system in which the primary environment is virtual but the environment is augmented by real elements. In this real-time environment, the surgeon can easily and intuitively identify the tool, surgical targets, and high risk areas, and view tool trajectories and orientations.

Abstract: An ablation system is provided that includes an ablating device and a probe. The probe is configured to be positioned in close proximity to a region of non-targeted tissue proximate an ablation site of targeted tissue. The probe includes an elongate shaft having proximal and distal ends, with a handle disposed at the proximal end thereof and a tissue protecting apparatus disposed at the distal end thereof. The ablating device includes an elongate shaft having proximal and distal ends, with a handle mounted at the proximal end thereof and an ablation element mounted at the distal end thereof. The ablation element includes an ultrasound transducer and an inflatable balloon surrounding the ultrasound transducer. The balloon includes a layer of gel disposed on its outer surface.

Abstract: A system and method for facilitating the healing of a skin ulcer, such as a diabetic ulcer, on a treatment region of a body. Ultrasound waves are transmitted to the treatment region. Interferential electrical stimulation is applied to the treatment region, simultaneously with the ultrasound transmission. The treatment region may be massaged with a massaging device during the treatment session. A gel may be applied onto the treatment region to facilitate the ultrasound transmission and electrical stimulation. A measurement system may be used to obtain accurate measurements of the skin ulcer, to provide a quantitative determination of the healing progression.

Abstract: A robotically controlled surgical tool including a lockout mechanism is provided. The surgical tool may comprise an instrument mounting portion. The instrument mounting portion includes a housing, a plate, a shaft assembly comprising an end effector, and a coupler to couple the shaft assembly to the instrument mounting portion. The end effector comprises a first jaw member and a second jaw member, the first and second jaw members defining a channel therebetween, and a blade slideably receivable within the channel to cut tissue located between the first and second jaw members. The surgical tool may include an actuation mechanism to actuate the end effector to provide reciprocating movement of the blade within the channel. A lockout mechanism is coupled to the actuation mechanism. The lockout mechanism may selectively enable reciprocating movement of the blade. An interface mechanically and electrically couples the instrument mounting portion to a robotic manipulator.

Abstract: Patient specific temperature distribution in organs, due to an ablative device, is simulated. The effects of ablation are modeled. The modeling is patient specific. The vessel structure for a given patient, segmented from medical images, is accounted for as a heat sink in the model of biological heat transfer. A temperature map is generated to show the effects of ablation in a pre-operative analysis. Temperature maps resulting from different ablation currents and ablation device positions may be used to determine a more optimal location of the ablative device for a given patient. Other models may be included, such as accounting for the tissue damage during the ablation.

Abstract: Apparatus comprising an ultrasound ablation system (10), which comprises a reflection-facilitation element (12), configured to be placed at an extramyocardial site of a subject, and to provide an extramyocardial reflective region; and an ultra-sound tool (20), which comprises at least one ultrasound transducer (40) configured to be positioned within a heart chamber of the subject. The ultrasound transducer (40) is configured to ablate myocardial tissue by applying ultrasound energy to the myocardial tissue such that at least a portion of the transmitted energy is reflected by the reflective region onto the myocardial tissue. Other embodiments are also described.

Abstract: The medical systems, apparatuses and uses thereof for treating obesity and/or obesity-related diseases are provided which relate to devices designed to stimulate an internal surface of the stomach such as the cardia. Features of the obesity treatment devices include insertion of said devices transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The devices include flotation portions and cardia-stimulating portions, so that as the level of stomach contents rise, the devices will contact and stimulate the nerves in the cardia region of the stomach to induce satiety. The devices may have non-inflatable balls, be made of skinned foam, have ballast members such as a weighted ball or quantity of saline for orientation, and various combinations thereof.

Abstract: Various example embodiments are directed towards a system and method for closed feedback control of a robotically controlled electrosurgical instrument. In one embodiment, the method comprises applying at least one electrosurgical signal to an electrosurgical end effector a robotically controlled surgical instrument. A feedback signal may be generated by the electrosurgical end effector and provided to a control logic. The control logic may be configured to determine a rate of change of the impedance of a target tissue based on the feedback signal received from the electrosurgical end effector. The control logic may be configured to control or modify the at least one electrosurgical signal such that the rate of change of impedance determined from the feedback signal is maintained at a predetermined rate or within a predetermined range.

Abstract: Devices and methods for treating biological tissue using a plasma gas-discharge are disclosed herein. An electrode for igniting a gas flow to form a plasma gas-discharge, wherein the electrode is configured within the device such that upon encountering a surface of the biological tissue by the electrode, a path of current from the electrode to the surface of the biological tissue is formed, thereby igniting the gas flow and forming the plasma gas-discharge. In some embodiments, electromagnetic interactions between the treated biological tissue and the plasma gas discharge traversing the electromagnetic interaction gap shape the profile of the plasma gas discharge. According to some embodiments, the device includes an electrode for igniting gas of the gas flow, and electromagnetic interactions between the electrode and the skin determine, at least in part, the electromagnetic interactions that shape the profile of the plasma gas discharge.

Abstract: Some embodiments described herein generally relate to apparatus and methods for treating diverticula. The diverticula may be present within a wall of a gastrointestinal organ, such as a colon, of a human or animal. In some examples, the apparatus may include a flexible conduit having a proximal end, a distal end, and a passageway therethrough, a balloon-forming chamber at the distal end of the flexible conduit, and at least one heating element positioned on an interior of the balloon-forming chamber. The apparatus may further include an endoscope in which the flexible conduit may be positioned such that the balloon-forming chamber extends from an end of the endoscope.

Abstract: A surgical instrument is provided and includes a housing having a shaft. An end effector assembly is operatively connected to a distal end of the shaft and has a pair of first and second jaw members one of which is movable with respect to the other. A heat activated drive assembly operably couples to an actuation mechanism that is operably associated with the forceps and configured to supply thermal energy to the heat activated drive assembly. The heat activated drive assembly operably coupled to movable jaw member and configured to impart movement of the movable jaw member when the actuation mechanism is activated.

Abstract: Devices, systems, and methods for degassing fluid prior to applying fluid to a treatment site during ablation therapy are provided. In one embodiment, an ablation system can include an elongate body, an ablation element, a heating assembly, and a fluid source. Fluid in the fluid source can be at least partially degassed prior to being provided as part of the system, or, in some embodiments, a degassing apparatus can be provided that can be configured to degas fluid within the system prior to applying the fluid to the treatment site. The degassing apparatus can include one or more gas-permeable and fluid-impermeable tubes disposed therein, which can allow gas to be removed from fluid passing through the apparatus. Other exemplary devices, systems, and methods are also provided.

Abstract: An endoscopic device for generating acoustic waves with a sheath defining a center axis contains a first transducer for generating a first beam of acoustic energy radiating outwards of the endoscope sheath and a second transducer for generating a second beam of acoustic energy radiating outwards of the endoscope sheath. Both beams have different directions and intersect outside of the endoscope forming a focus spot. The second transducer is linearly movable parallel to the center axis with respect to the first transducer to displace the second beam and therefore to displace the intersection of the beams and therefore of the focus spot.

Abstract: Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.

Abstract: An endoscopic bipolar forceps includes a housing having a shaft affixed thereto, the shaft including jaw members at a distal end thereof. The forceps also includes a drive assembly which moves the jaw member relative to one another for manipulating tissue and a knife assembly for cutting tissue disposed between jaw members. The forceps also includes a knife lockout mechanism operatively connected to the drive assembly. Movement of the drive assembly moves the knife lockout mechanism from a first orientation in obstructive relationship with the knife bar to prevent movement thereof to a second position which allows selective, unencumbered movement of the knife assembly to cut tissue disposed between the jaw members.

Abstract: Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.

Abstract: Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

Abstract: The invention relates to a combined ultrasound and HF surgical system, including at least one ultrasound generator which operatively provides an excitation signal through which an ultrasound converter can generate an ultrasound vibration, at least one HF generator which operatively generates HF energy, and at least one ultrasound and HF instrument electrically connected with the HF generator and the ultrasound generator, wherein the ultrasound vibrations and the HF energy are introducible into biological tissue through the HF instrument which includes at least one ultrasound converter and at least one HF electrode. In order to be able to use HF energy and ultrasound energy simultaneously without damaging the instrument or wearing the it out, the system includes a protective device which prevents sparks operatively generated through HF energy or reduces the probability of occurrence of the sparks.

Abstract: In one aspect, the present disclosure is directed to a method for treating a bladder within a body of a subject, including inserting one or more heaters into the bladder wall of a subject, and selectively heating the one or more heaters by a remote device.

Abstract: A method and apparatus for treatment of pulmonary conditions, including a device having an end effector sized and shaped to contact a nerve component on the exterior of a bronchial segment and apply energy to that nerve component.

Abstract: Embodiments disclosed herein are directed to fluid spraying apparatuses, and related systems and methods. The disclosed fluid spraying apparatuses may be used, for example, to spray a medically suitable fluid on a target region of a subject, such as for treating or removing tissue of the subject. In an embodiment, a fluid spraying apparatus includes a spray mechanism including at least one reservoir, and a spraying device operably coupled to the at least one reservoir which has an adjustable spray nozzle. The fluid spraying apparatus includes a distance sensor configured to sense information at least related to a distance to a target region of a subject and output one or more signals encoding the information, and control electrical circuitry operably coupled to the spray mechanism and the distance sensor. The control electrical circuitry is configured to activate the spray mechanism responsive to receiving the one or more signals.

Abstract: The method determines parameters to generate confocal ultrasound beams (B1,B2) inside a medium (4), and uses a device (1) comprising first and second ultrasound means (11,12) and first and second displacement members (13,14) for moving the ultrasound means (11,12). The parameters include signals s1,s2 to the ultrasound means (11,12), and the positions x1,x2 of the ultrasound means (11,12). The parameters are optimized for having a minimum amplitude a1,a2 of the signals s1,s2 and having an acoustic effect inside the medium (4).

Abstract: Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to methods including selectively neuromodulating afferent or efferent renal nerves. One or more measurable physiological parameters corresponding to systemic sympathetic overactivity or hyperactivity in the patient can thereby be reduced. Selectively neuromodulating afferent renal nerves can include inhibiting sympathetic neural activity in nerves proximate a renal pelvis. This can include, for example, neuromodulating via fluid within the renal pelvis. Selectively neuromodulating efferent renal nerves can include inhibiting sympathetic neural activity in nerves proximate a portion of a renal artery or a renal branch artery proximate a renal parenchyma. This can include, for example, neuromodulating via a therapeutic element within the portion of the renal artery or the renal branch artery.

Abstract: Disclosed are vertebroplasty methods that include cauterizing an inner cavity of a vertebra of a mammal, such as a human, and injecting bone cement into the vertebra. Systems and kits for performing such methods are also disclosed.

Abstract: This invention concerns a cover member, especially for a HIFU head, comprising a peripheral outer wall, an open first side configured to partially cover an ultrasound head and a closed second side comprising a flexible membrane adapted for contact with a patient's skin, characterized in that the cover member is removeably attachable to the tip of said ultrasound probe.

Abstract: Provided herein are methods, systems, and devices for increasing IL-10 expression, inhibiting inflammation, and treating inflammatory conditions using thermal ablation.

Abstract: The present invention is directed toward a device that performs ablation of tissue. The device has a catheter with a shaft through which an ablative agent can travel, a first positioning element attached to the catheter shaft at a first position and a second positioning element attached to the catheter shaft at a second position. The shaft also has ports through which the ablative agent can be released.

Abstract: In one general aspect, various embodiments are directed to a surgical instrument that can supply mechanical energy and electrical energy to an end effector of the surgical instrument. The surgical instrument comprises an ultrasonic generator module coupled to an ultrasonic drive system, which comprises an ultrasonic transducer coupled to a waveguide and an end effector coupled to the waveguide. The ultrasonic drive system is configured to resonate mechanically at a resonant frequency to generate a first ultrasonic drive signal. An electronic circuit is coupled to the ultrasonic generator module to monitor an electrical characteristic of the ultrasonic drive system. A processor is coupled to the electronic circuit to control the ultrasonic drive signal in response to the monitored electrical characteristic of the ultrasonic drive system.

Abstract: A method is provided, including, delivering into a heart of a patient an annuloplasty ring structure including a body portion and an adjusting mechanism configured to adjust a size of the body portion of the annuloplasty ring structure, the adjusting mechanism including a housing, and following the delivering, moving the housing with respect to the body portion. Other applications are also described.