Respiratory Movement Patents (Class 607/20)
  • Patent number: 10118041
    Abstract: Techniques for performing lead functionality tests, e.g., lead impedance tests, for implantable electrical leads are described. In some of the described embodiments, an implantable medical device determines whether a patient is in a target activity state, e.g., an activity state in which lead impedance testing will be unobtrusive, such as when a patient is asleep, or capture information of particular interest, such as when the patient is active, in a particular posture, or changing postures. The implantable medical device performs the lead functionality test based on this determination. Additionally, in some embodiments, the implantable medical device may group a plurality of measurements for a single lead functionality test into a plurality of sessions, and perform the measurement sessions interleaved with delivery of therapeutic stimulation.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: November 6, 2018
    Assignee: Medtronic, Inc.
    Inventors: Steven M. Goetz, Nathan A. Torgerson, Michael T. Lee
  • Patent number: 10005285
    Abstract: The application provides an ink cartridge chip applied in an ink cartridge which is detachably installed in an imaging device. The ink cartridge chip includes an interface unit and a control unit. The interface unit receives a light control command from the imaging device, which may be a light-lighting-up or a light-extinguishing command. The control unit is connected to a light-emitting unit, and lights up the light-emitting unit on detecting that the ink cartridge chip is in a power-up initialization stage. And the control unit is also connected to the interface unit, and determines, in a case that the light control command is a light-extinguishing command, whether a preset extinguishing condition is satisfied, extinguishes the light-emitting unit if the preset extinguishing condition is satisfied, and maintains a current state of the light-emitting unit if the light control command is a light-lighting-up command.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: June 26, 2018
    Assignee: APEX MICROELECTRONICS CO., LTD.
    Inventors: Wei Zhou, Juhui Li, Hao Chen, Yanhui Luo
  • Patent number: 9592676
    Abstract: An ink cartridge chip includes an interface unit, a control unit, and a storage unit, wherein the interface unit is configured to receive a light control command sent from an imaging device, and the light control command includes ink cartridge identification information; the storage unit is configured to store autogenic identification information and a state flag, and the state flag includes an executable state or a non-executable state; the control unit is configured to execute the light control command; and the control unit is is configured to, when the interface unit receives the light control command, control the light-emitting unit to execute the light control command based on the type of the light control command and the state flag in the storage unit to re-determined the state flag.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: March 14, 2017
    Assignee: Apex Microelectronics Co., Ltd.
    Inventors: Wei Zhou, Juhui Li, Hao Chen, Yanhui Luo
  • Patent number: 9538954
    Abstract: An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea and hypopnea and to identify an occurrence of periodic respiration. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: January 10, 2017
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Abhilash Patangay, Yachuan Pu
  • Patent number: 9456787
    Abstract: A biometric monitoring device is used to determine a user's heart rate by using a heartbeat waveform sensor and a motion detecting sensor. In some embodiments, the device collects collecting concurrent output data from the heartbeat waveform sensor and output data from the motion detecting sensor, detects a periodic component of the output data from the motion detecting sensor, and uses the periodic component of the output data from the motion detecting sensor to remove a corresponding periodic component from the output data from the heartbeat waveform sensor. From this result, the device may determine and present the user's heart rate.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: October 4, 2016
    Assignee: Fitbit, Inc.
    Inventors: Subramaniam Venkatraman, Shelten Gee Jao Yuen
  • Patent number: 9421383
    Abstract: An example of a system includes an implantable medical device (IMD) for implantation in a patient, where the IMD includes a cardiac pace generator, phrenic nerve stimulation (PS) sensor, a memory, and a controller, and where the controller is operably connected to the cardiac pace generator to generate cardiac paces. The controller is configured to provide a trigger for conducting a PS detection procedure and perform the PS detection procedure in response to the trigger. In performing the PS detection procedure the controller is configured to receive a signal from the sensor, detect PS using the signal from the sensor, and record the PS detection in storage within the IMD.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: August 23, 2016
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Holly Rockweiler, Sunipa Saha, Aaron R. McCabe, Krzysztof Z. Siejko
  • Patent number: 9295404
    Abstract: An apparatus for measuring complex electrical admittance and/or complex electrical impedance in animal or human patients includes a first electrode and at least a second electrode which are adapted to be disposed in the patient. The apparatus includes a housing adapted to be disposed in the patient. The housing has disposed in it a stimulator in electrical communication with at least the first electrode to stimulate the first electrode with either current or voltage, a sensor in electrical communication with at least the second electrode to sense a response from the second electrode based on the stimulation of the first electrode, and a signal processor in electrical communication with the sensor to determine the complex electrical admittance or impedance of the patient.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: March 29, 2016
    Assignees: Admittance Technologies, Inc., Board of Regents, The University of Texas System
    Inventors: Jonathan W. Valvano, Marc D. Feldman, John Porterfield, John A. Pearce, Erik Larson, Lev Shuhatovich, Kathryn Loeffler, Raffaele Cetrulo
  • Patent number: 9212962
    Abstract: In one embodiment, a pressure sensor assembly includes an accelerometer configured to produce a first current upon movement of the accelerometer, a capacitor configured to receive the first current thereby charging the capacitor, a gate element operably connected to the capacitor and configured to discharge a second current from the capacitor upon the capacitor attaining a threshold voltage, a pressure sensor configured to receive the discharged current to produce a first signal corresponding to at least one pressure reading of the pressure sensor, and a transmitter operably connected to the pressure sensor and configured to transmit a second signal based upon the first signal to an external device configured to store data corresponding to the second signal.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: December 15, 2015
    Assignee: Robert Bosch GmbH
    Inventor: Stephen J. Brown
  • Patent number: 9108419
    Abstract: The present invention provides a method for controlling an ink cartridge chip, the ink cartridge chip and an ink cartridge. The ink cartridge chip comprises an interface unit and a control unit, wherein the interface unit is connected to an image forming apparatus and used for receiving a light control instruction sent by the image forming apparatus; the light control instruction includes a light-on instruction used for indicating the illumination of a light-emitting unit on the ink cartridge chip; and the control unit is used for controlling whether to execute the light control instruction according to the state of the ink cartridge chip when the interface unit receives the light control instruction, and updating the state of the ink cartridge chip according to the light control instruction. The present invention also provides a corresponding control method and an ink cartridge.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: August 18, 2015
    Assignee: Apex Microelectronics Company Limited
    Inventors: Hao Chen, Weichen Liu
  • Patent number: 8996108
    Abstract: An implantable cardiac device includes a sensor for sensing patient activity and detecting phrenic nerve activation. A first filter channel attenuates first frequencies of the sensor signal to produce a first filtered output. A second filter channel attenuates second frequencies of the accelerometer signal to produce a second filtered output. Patient activity is evaluated using the first filtered output and phrenic nerve activation caused by cardiac pacing is detected using the second filtered output.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: March 31, 2015
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Aaron R. McCabe, Holly E. Rockweiler, Jacob I. Laughner
  • Patent number: 8914107
    Abstract: A cardiac rhythm management (CRM) device can extract ventilation information from thoracic impedance or other information, and adjust a delivery rate of the CRM therapy. A tidal volume of a patient is measured and used to adjust a ventilation rate response factor. The measured tidal volume can optionally be adjusted using a ventilation rate dependent adjustment factor. The ventilation rate response factor can also be adjusted using a maximum voluntary ventilation (MVV), an age predicted maximum heart rate, a resting heart rate, and a resting ventilation determined for the patient. In various examples, a global ventilation sensor rate response factor (for a population) can be programmed into the CRM device, and automatically tailored to be appropriate for a particular patient.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: December 16, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Paul F. Emerson, Gary T. Seim, Michael A. Querimit, Donald L. Hopper, Stephen R. Pitzl, Daniel O'Brien
  • Patent number: 8876727
    Abstract: A method and system of detecting phrenic nerve stimulation in a patient that includes detecting an activation event, obtaining a heart sound signal of a patient from an implanted heart sound sensor, determining that an electrical stimulation has been applied to the patient, in response to detecting the activation event, monitoring a portion of the heart sound signal, the portion defined by a predetermined window after the application of the electrical stimulation, and determining whether phrenic nerve stimulation occurred based on the portion of the heart sound signal.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: November 4, 2014
    Assignee: Medtronic, Inc.
    Inventors: Xusheng Zhang, Jeffrey M. Gillberg, Thomas J. Mullen, Paul J. DeGroot
  • Patent number: 8880171
    Abstract: A system comprising implantable device, the implantable medical device including an intrinsic cardiac signal sensor, an impedance measurement circuit configured to apply a specified current to a transthoracic region of a subject and to sample a transthoracic voltage resulting from the specified current, and a processor coupled to the intrinsic cardiac signal sensor and the impedance measurement circuit. The processor is configured to initiate sampling of a transthoracic voltage signal in a specified time relation to a fiducial marker in a sensed intrinsic cardiac signal, wherein the sampling attenuates or removes variation with cardiac stroke volume from the transthoracic voltage signal, and determine lung respiration using the sampled transthoracic voltage signal.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: November 4, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jaeho Kim, Quan Ni
  • Patent number: 8818509
    Abstract: Implantable element having an elongate main body, a functional conductor which extends in the longitudinal direction of the main body or forms it, and which acts to implement a medical function of the element and has an inductive section, and magnetic flux generation means for generating a magnetic flux in the surroundings of the functional conductor, in particular of its inductive section, which are magnetically coupled to the functional conductor in such a way that the magnetic flux generated upon a current flux through the functional conductor is counteracted and the current flux density through the functional conductor is thus reduced.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: August 26, 2014
    Assignee: Biotronik SE & Co. KG
    Inventor: Ingo Weiss
  • Patent number: 8805511
    Abstract: A medical device and associated method detect ischemia using stimulation delivered to induce respiration. A spontaneous breathing response to the stimulation-induced respiration is determined. Ischemia is detected in response to the spontaneous breathing response. The spontaneous breathing response is measured as a response to adjusting a parameter controlling the stimulation.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: August 12, 2014
    Assignee: Medtronic, Inc.
    Inventors: Mustafa Karamanoglu, Vincent E. Splett, Nancy J. Rakow, Linnea R. Lentz
  • Patent number: 8712518
    Abstract: The invention relates to methods and systems for determining phase-specific parameters of a physiological variable, and a related computer program and a related machine-readable storage medium, which are usable in particular to determine parameters of physiological variables that are subject to circadian variation. To this end, phase-specific parameters of a physiological variable X(t) are determined by calculating, at least for a portion of values x lying in a specifiable time period, a mean g(x|?) in each case of values X(t+?) for which X(t)=x applies for their predecessors, ? describing a time interval, and determining the phase-specific parameters by evaluating the mean g(x|?).
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: April 29, 2014
    Assignee: Biotronik SE & Co. KG
    Inventors: Jens Kirchner, Christian Rockstroh, Thomas Kraemer
  • Publication number: 20140114371
    Abstract: A lead system for an implantable medical device and applications for the lead system. Also includes therapeutic systems, devices, and processes for detecting and treating disordered breathing and treating cardiac and breathing issues together with an implantable device.
    Type: Application
    Filed: March 27, 2013
    Publication date: April 24, 2014
    Applicant: Respicardia, Inc.
    Inventors: Randy W. Westlund, Kristofer J. James, Mark Gelfand
  • Patent number: 8688214
    Abstract: A system comprising implantable device, the implantable medical device including an intrinsic cardiac signal sensor, an impedance measurement circuit configured to apply a specified current to a transthoracic region of a subject and to sample a transthoracic voltage resulting from the specified current, and a processor coupled to the intrinsic cardiac signal sensor and the impedance measurement circuit. The processor is configured to initiate sampling of a transthoracic voltage signal in a specified time relation to a fiducial marker in a sensed intrinsic cardiac signal, wherein the sampling attenuates or removes variation with cardiac stroke volume from the transthoracic voltage signal, and determine lung respiration using the sampled transthoracic voltage signal.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: April 1, 2014
    Assignee: Cardiac Pacemakers. Inc.
    Inventors: Jaeho Kim, Quan Ni
  • Patent number: 8655446
    Abstract: Methods and systems involve adjusting cardiac pacing based on information acquired via a respiratory therapy device. A medical system includes a respiratory therapy device having one or more sensors and a therapy delivery unit. The one or more sensors are configured to sense respiration cycles. The therapy delivery unit is configured to deliver an external respiratory therapy to the patient. The medical system also includes a pulse generator configured to deliver cardiac pacing pulses to the patient. A controller is coupled to the one or more sensors and the pulse generator. The control unit configured to adjust a cardiac pacing rate based on the patient's respiration cycles.
    Type: Grant
    Filed: November 27, 2007
    Date of Patent: February 18, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jeffrey E. Stahmann, Jesse W. Hartley, Kent Lee, Quan Ni
  • Patent number: 8639318
    Abstract: Systems, devices and methods for defining, identifying and utilizing composite parameter indices from health-related parameters are disclosed. One aspect is a programmable device having machine executable instructions for performing a method to assist with managing a patient's health. In various embodiments, a first set of at least two health-related parameters is acquired. A first composite parameter is generated using the first set of at least two health-related parameters. Other aspects and embodiments are provided herein.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: January 28, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: John D. Hatlestad, Jeffrey E. Stahmann, Qingsheng Zhi
  • Patent number: 8634915
    Abstract: An implantable cardiac device includes a sensor for sensing patient activity and detecting phrenic nerve activation. A first filter channel attenuates first frequencies of the sensor signal to produce a first filtered output. A second filter channel attenuates second frequencies of the accelerometer signal to produce a second filtered output. Patient activity is evaluated using the first filtered output and phrenic nerve activation caused by cardiac pacing is detected using the second filtered output.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: January 21, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Aaron R. McCabe, Holly E. Rockweiler, Jacob L. Laughner
  • Patent number: 8628471
    Abstract: Systems and Methods for predicting patient health and patient relative well-being within a patient management system are disclosed. A preferred embodiment utilizes an implantable medical device comprising an analysis component and a sensing component further comprising a three-dimensional accelerometer, a transthoracic impedance sensor, a cardio-activity sensor, an oxygen saturation sensor and a blood glucose sensor. Some embodiments of a system disclosed herein also can be configured as an Advanced Patient Management System that helps better monitor, predict and manage chronic diseases.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: January 14, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Scott T. Mazar, Richard Fogoros, Yatheendhar D. Manicka, Bruce H. KenKnight, Michael J. Pederson
  • Publication number: 20140012346
    Abstract: The current technology is relevant to a system having a programming device capable of communication with an implantable medical device, where the a programming device is configured to identify a patient condition comprising the patient's inability to exercise to a desired capacity, configured to notify a clinical user of the identified condition and configured to identify a therapy appropriate for the identified condition.
    Type: Application
    Filed: July 1, 2013
    Publication date: January 9, 2014
    Inventors: James O. Gilkerson, Kenneth P. Hoyme, James R. Kalgren, David L. Perschbacher, Les N. Peterson
  • Patent number: 8626292
    Abstract: An implantable cardiac device includes a sensor for sensing patient respiration and detecting phrenic nerve activation. A first filter channel attenuates first frequencies of the sensor signal to produce a first filtered output. A second filter channel attenuates second frequencies of the respiration signal to produce a second filtered output. Patient activity is evaluated using the first filtered output and phrenic nerve activation caused by cardiac pacing is detected using the second filtered output.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: January 7, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Aaron R. McCabe, Holly E. Rockweiler, Jacob L. Laughner
  • Publication number: 20130331901
    Abstract: A method and apparatus for treatment of hypertension and heart failure by increasing secretion of endogenous atrial hormones by pacing of the heart atria. Atrial pacing is done during the ventricular refractory period resulting in premature atrial contraction that does not result in ventricular contraction. Pacing results in the atrial wall stress, peripheral vasodilation, ANP secretion. Concomitant reduction of the heart rate is monitored and controlled as needed with backup pacing.
    Type: Application
    Filed: November 29, 2012
    Publication date: December 12, 2013
    Applicant: BACKBEAT MEDICAL, INC.
    Inventor: BackBeat Medical, Inc.
  • Patent number: 8600497
    Abstract: An implantable device monitors and treats heart failure, pulmonary edema, and hemodynamic conditions and in some cases applies therapy. In one implementation, the implantable device applies a high-frequency multi-phasic pulse waveform over multiple-vectors through tissue. The waveform has a duration less than the charging time constant of electrode-electrolyte interfaces in vivo to reduce intrusiveness while increasing sensitivity and specificity for trending parameters. The waveform can be multiplexed over multiple vectors and the results cross-correlated or subjected to probabilistic analysis or thresholding schemata to stage heart failure or pulmonary edema. In one implementation, a fractionation morphology of a sensed impedance waveform is used to trend intracardiac pressure to stage heart failure and to regulate cardiac resynchronization therapy. The waveform also provides unintrusive electrode integrity checks and 3-D impedancegrams.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: December 3, 2013
    Assignee: Pacesetter, Inc.
    Inventors: Weiqun Yang, Malin Ohlander, Louis Wong, Nils Holmstrom, Cem Shaquer, Euljoon Park, Dorin Panescu, Shahrooz Shahparnia, Andre Walker, Ajit Pillai, Mihir Naware
  • Patent number: 8600502
    Abstract: Systems and methods for sleep state classification involve detecting conditions related to sleep, including at least one condition associated with rapid eye movement (REM) sleep. Additionally, a condition modulated by the sleep-wake status of the patient may be detected. A medical system that is partially or fully implantable incorporates sensors and circuitry for detecting and processing the sleep-related signals. A sleep state processor classifies the patient's sleep state based on the sleep-related signals. Sleep state classification may be used in connection with the delivery of sleep state appropriate therapy, diagnostic testing, or patient monitoring.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: December 3, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Eric G. Lovett, Robert J. Sweeney, Bruce H. KenKnight
  • Patent number: 8560067
    Abstract: A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 15, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Rodney W. Salo, Julio C. Spinelli, Bruce H. KenKnight
  • Patent number: 8538526
    Abstract: A rate-adaptive pacemaker and a method for its operation in which the response factor for a minute ventilation sensor or other type of exertion level sensor is automatically set during a parameter adjustment mode that utilizes an activity level measurement to determine when the patient is at a target activity level with which is associated an appropriate target pacing rate. In a preferred embodiment, the target activity level corresponds to casual walking (e.g., 2 mph at a 4% grade) with a target pacing rate selected as appropriate for that level of activity in the individual patient.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: September 17, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jeffrey E. Stahmann, Michael A. Querimit, Donald L. Hopper, Brian Ralph Larson, Paul F. Emerson, Daniel O'Brien
  • Patent number: 8532771
    Abstract: A maximum pacing rate limiter for use in adaptive rate pacing in conjunction with a cardiac rhythm management system for a heart. The maximum pacing rate limiter may function to measure an interval, termed the ERT interval, between a paced ventricular evoked response and a T-wave. The maximum pacing rate limiter may further function to maintain the ERT interval at less than a certain percentage of the total cardiac cycle. In one disclosed embodiment, a maximum pacing rate limiter calculates an ERT rate based on the detected paced ventricular evoked response and the T-wave, and the pacing rate limiter module further communicates the minimum of the ERT rate and an adaptive-rate sensor indicated rate to a pacemaker.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: September 10, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Douglas R. Daum, Geng Zhang, Qingsheng Zhu, Gerrard M. Carlson, Julio C. Spinelli
  • Patent number: 8515535
    Abstract: Cardiac monitoring and/or stimulation methods and systems employing dyspnea measurement. An implantable cardiac device may sense transthoracic impedance and determine a patient activity level. An index indicative of pulmonary function is implantably computed to detect an episode of dyspnea based on a change, trend, and/or value exceeding a threshold at a determined patient activity level. Trending one or more pulmonary function index values may be done to determine a patient's pulmonary function index profile, which may be used to adapt a cardiac therapy. A physician may be automatically alerted in response to a pulmonary function index value and/or a trend of the patient's pulmonary index being beyond a threshold. Computed pulmonary function index values and their associated patient's activity levels may be stored periodically in a memory and/or transmitted to a patient-external device.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: August 20, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Donald L. Hopper, John M. Voegele, Jesse W. Hartley, Avram Scheiner
  • Patent number: 8509902
    Abstract: Medical devices and methods for providing breathing therapy (e.g., for treating heart failure, hypertension, etc.) may determine at least the inspiration phase of one or more breathing cycles based on the monitored physiological parameters and control delivery of a plurality of breathing therapy sessions (e.g., each of the breathing therapy sessions may be provided during a defined time period). Further, each of the plurality of breathing therapy sessions may include delivering stimulation after the start of the inspiration phase of each of a plurality of breathing cycles to prolong diaphragm contraction during the breathing cycle.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: August 13, 2013
    Assignee: Medtronic, Inc.
    Inventors: Yong K. Cho, Shaileshkumar Musley, Avram Scheiner
  • Patent number: 8467870
    Abstract: A method includes controlling a cardiac pacing rate of an implantable medical device (IMD) to control a heart rate of a patient and determining that the patient is in a resting state. The method further includes modifying the pacing rate of the IMD for N cardiac cycles in response to determining that the patient is in the resting state. N is an integer greater than 1. Modifying the pacing rate includes incrementally increasing the pacing rate for a first portion of the N cardiac cycles, and incrementally decreasing the pacing rate for a second portion of the N cardiac cycles.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: June 18, 2013
    Assignee: Medtronic, Inc.
    Inventors: Yong Kyun Cho, Mark K. Erickson, Tommy D. Bennett
  • Publication number: 20130123873
    Abstract: Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein.
    Type: Application
    Filed: December 31, 2012
    Publication date: May 16, 2013
    Inventors: Imad Libbus, Krzysztof Z. Siejko, Marina V. Brockway, Robert J. Sweeney
  • Patent number: 8442633
    Abstract: A system comprising implantable device, the implantable medical device including an intrinsic cardiac signal sensor, an impedance measurement circuit configured to apply a specified current to a transthoracic region of a subject and to sample a transthoracic voltage resulting from the specified current, and a processor coupled to the intrinsic cardiac signal sensor and the impedance measurement circuit. The processor is configured to initiate sampling of a transthoracic voltage signal in a specified time relation to a fiducial marker in a sensed intrinsic cardiac signal, wherein the sampling attenuates or removes variation with cardiac stroke volume from the transthoracic voltage signal, and determine lung respiration using the sampled transthoracic voltage signal.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: May 14, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jaeho Kim, Quan Ni
  • Patent number: 8442638
    Abstract: An approach to providing disordered breathing therapy includes delivering electrical stimulation therapy modifying a patient's baroreflex response. Disordered breathing therapy may be delivered in response to prediction or detection of disordered breathing events. Various conditions affecting the patient may be evaluated and the baroreflex therapy modified. The therapy may be modified to improve therapy efficacy, to reduce an impact to the patient and/or to mitigate therapy interactions.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: May 14, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Imad Libbus, Quan Ni, Kent Lee
  • Patent number: 8412328
    Abstract: Systems and techniques for applying an electromagnetic field to bodily tissue include a self-contained and portable electromagnetic field generating device disposed over a surface of bodily tissue such that the radiated electromagnetic fields impinge upon the bodily tissue. The device includes an electromagnetic field generator, which is coupled to an antenna that is arranged to radiate the electromagnetic field. A power source is coupled to the generator to provide power for the device and an activator is used to initiate radiation of the electromagnetic field. Methods of inducing electrical current in bodily tissues and treating disorders, such as pain-related disorders, are also disclosed.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: April 2, 2013
    Assignee: BioElectronics Corp.
    Inventors: Andrew J. Whelan, John Martinez, Timothy Cox, Stephanie Toy, James Woodhams
  • Patent number: 8401666
    Abstract: In general, the disclosure describes techniques for modifying therapy provided to a patient by a medical device. The techniques may be applicable to electrical stimulation therapy or other therapies. Modification of therapy may include adjustment of one or more therapy parameter values that define one or more characteristics of stimulation therapy delivered to a patient. The therapy modification may be based on activity of a patient that is detected by an IMD, such as a change in a detected posture state occupied by the patient. Different therapy modifications may be applied for different changes in detected posture state. An IMD may modify therapy based on a transition from one posture state to another posture state, and apply different modifications for different transitions. In some aspects, the modification may include a profile, such as a ramp up or ramp down in a parameter value over a period of time. The profile may be different for different posture transitions.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: March 19, 2013
    Assignee: Medtronic, Inc.
    Inventors: Dennis M. Skelton, Jon P. Davis, Rajeev Sahasrabudhe, Shyam Gokaldas, Joseph J. Nolan, Dennis Bourget, Duane Bourget, Keith A. Miesel, James Zimmerman
  • Publication number: 20130053907
    Abstract: An implantable medical device includes a multi-axial acceleration sensor and an evaluation unit connected thereto. The evaluation unit is configured to (1) split the accelerometer output signal into at least two signal components, one of which is associated with a right-ventricular contraction and another of which is associated with a left-ventricular contraction; (2) detect events in the signal components, and/or determine signal features therein; and (3) determine at least one characteristic value K by evaluating the signal components, and/or the events and/or signal features therein.
    Type: Application
    Filed: August 17, 2012
    Publication date: February 28, 2013
    Inventors: Jens Kirchner, Michael Vollkron, Olaf Skerl
  • Publication number: 20130030488
    Abstract: Medical devices and methods for providing breathing therapy (e.g., for treating heart failure, hypertension, etc.) may determine at least the inspiration phase of one or more breathing cycles based on the monitored physiological parameters and control delivery of a plurality of breathing therapy sessions (e.g., each of the breathing therapy sessions may be provided during a defined time period). Further, each of the plurality of breathing therapy sessions may include delivering stimulation after the start of the inspiration phase of each of a plurality of breathing cycles to prolong diaphragm contraction during the breathing cycle.
    Type: Application
    Filed: July 28, 2011
    Publication date: January 31, 2013
    Applicant: Medtronic, Inc.
    Inventors: Yong K. Cho, Shaileshkumar Musley, Avram Scheiner
  • Patent number: 8364260
    Abstract: An external defibrillator having a battery; a capacitor electrically communicable with the battery; at least two electrodes electrically communicable with the capacitor and with the skin of a patient; a controller configured to charge the capacitor from the battery and to discharge the capacitor through the electrodes; and a support supporting the battery, capacitor, electrodes and controller in a deployment configuration, the defibrillator having a maximum weight per unit area in the deployment configuration of 0.1 lb/in2 and/or a maximum thickness of 1 inch. The support may be a waterproof housing.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: January 29, 2013
    Assignee: Kuman and Rao Family Trust
    Inventor: Uday N. Kumar
  • Patent number: 8359097
    Abstract: A method is presented for evaluating whether an episode of sleep apnea is occurring in a patient suffering from chronic sleep apnea disorder, for delivery of appropriate therapy. The method, performed by an implantable device, includes sensing the patient's EKG signal and using electrical energy generated by the heart to power subsequent signal processing. This signal is applied as the sole input to a differential signal processing circuit for passage through both a high impedance path and a substantially lower impedance path and amplification of the difference in magnitude between the resulting two signals, to determine changes in the patient's thoracic impedance. Based on such changes, the presence or absence of patient ventilation is detected, to enable an assessment of whether an episode of sleep apnea is occurring. An actual episode of sleep apnea is deemed to have occurred if lack of ventilation exceeds a predetermined interval of time between otherwise regular respiratory cycles.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: January 22, 2013
    Inventors: Eckhard Alt, Maik Gollasch
  • Publication number: 20120310295
    Abstract: An embodiment relates to a method for delivering a vagal stimulation therapy to a vagus nerve, including delivering a neural stimulation signal to non-selectively stimulate both afferent axons and efferent axons in the vagus nerve according to a predetermined schedule for the vagal stimulation therapy, and selecting a value for at least one parameter for the predetermined schedule for the vagal stimulation therapy to control the neural stimulation therapy to avoid physiological habituation to the vagal stimulation therapy. The parameter(s) include at least one parameter selected from the group of parameters consisting of a predetermined therapy duration parameter for a predetermined therapy period, and a predetermined intermittent neural stimulation parameter associated with on/off timing for the intermittent neural stimulation parameter.
    Type: Application
    Filed: August 14, 2012
    Publication date: December 6, 2012
    Inventors: Imad Libbus, Andrew P. Kramer
  • Patent number: 8323205
    Abstract: A method of identifying a potential cause of pulmonary edema is provided. The method includes obtaining one or more impedance vectors between predetermined combinations of the electrodes positioned proximate the heart. At least one of the impedance vectors is representative of a thoracic fluid level. The method also includes applying a stimulation pulse to the heart and sensing cardiac signals of the heart that are representative of an electrophysiological response to the stimulation pulse. The method further includes monitoring the cardiac signals and at least one of the impedance vectors with respect to time to identify the potential cause of pulmonary edema.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: December 4, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Euljoon Park, Steve Koh
  • Publication number: 20120290033
    Abstract: A method includes controlling a cardiac pacing rate of an implantable medical device to control a heart rate of a patient and detecting inhalation and exhalation of the patient. The method further includes determining that the patient is in a resting state, and, in response to determining that the patient is in the resting state, incrementally increasing the pacing rate while exhalation of the patient is detected and incrementally decreasing the pacing rate while inhalation of the patient is detected.
    Type: Application
    Filed: May 9, 2011
    Publication date: November 15, 2012
    Applicant: Medtronic, Inc.
    Inventors: Yong Kyun Cho, Mark K. Erickson, Tommy D. Bennett
  • Publication number: 20120290032
    Abstract: A method includes controlling a cardiac pacing rate of an implantable medical device (IMD) to control a heart rate of a patient and determining that the patient is in a resting state. The method further includes modifying the pacing rate of the IMD for N cardiac cycles in response to determining that the patient is in the resting state. N is an integer greater than 1. Modifying the pacing rate includes incrementally increasing the pacing rate for a first portion of the N cardiac cycles, and incrementally decreasing the pacing rate for a second portion of the N cardiac cycles.
    Type: Application
    Filed: May 9, 2011
    Publication date: November 15, 2012
    Applicant: Medtronic, Inc.
    Inventors: Yong Kyun Cho, Mark K. Erickson, Tommy D. Bennett
  • Patent number: 8311631
    Abstract: Adaptive rate pacing for improving heart rate kinetics in heart failure patients involves determining onset and sustaining of patient activity. The patient's heart rate response to the sustained activity is evaluated during a time window defined between onset of the activity and a steady-state exercise level. If the patient's heart rate response to the sustained activity is determined to be slow, a pacing therapy is delivered at a rate greater than the patient's intrinsic heart rate based on a profile of the patient's heart rate response to varying workloads. If determined not to be slow, the pacing therapy is withheld. Monitoring-only configurations provide for acquisition and organization of physiological data for heart failure patients. These data can be acquired on a per-patient basis and used to assess the HF status of the patient.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: November 13, 2012
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Donald Hopper, Yinghong Yu, Yanting Dong
  • Patent number: 8306621
    Abstract: A cardiac rhythm management device for obtaining transthoracic impedance. The device comprises a sensor for obtaining a signal indicative of an action of a heart, an impedance measurement circuit adapted to measure transthoracic impedance and a processor for utilizing the signal indicative of the action of the heart to sample the transthoracic impedance at sampling intervals commenced by fiducial markers in the signal indicative of the action of the heart, where the sampling of the impedance signal removes the component of a stroke volume of the heart from the signal and thereby provides lung ventilation information.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: November 6, 2012
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jaeho Kim, Quan Ni
  • Patent number: 8301252
    Abstract: Systems, devices and methods for defining, identifying and utilizing composite parameter indices from health-related parameters are disclosed. One aspect is a programmable device having machine executable instructions for performing a method to assist with managing a patient's health. In various embodiments, a first set of at least two health-related parameters is acquired. A first composite parameter is generated using the first set of at least two health-related parameters. Other aspects and embodiments are provided herein.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: October 30, 2012
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: John D. Hatlestad, Jeffrey E. Stahmann, Qingsheng Zhu
  • Patent number: 8280513
    Abstract: A device and method for detecting and treating airflow limitations in a subject is provided. Levels of flow limited breathing may be differentiated. Obstruction versus flow limited breathing may be differentiated as well. The EMG complex characteristics may be used to detect obstruction or flow limited breathing. The power spectral density plot of the EMG may be used to detect obstruction or flow limited breathing.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: October 2, 2012
    Assignee: RMX, LLC
    Inventors: Amir J. Tehrani, Rose Province, David Ligon