Parameter Control In Response To Sensed Physiological Load On Heart Patents (Class 607/17)
  • Patent number: 11911616
    Abstract: Devices, systems and methods provide forms of asymptomatic diaphragmatic stimulation (ADS) therapy that affect pressures within the intrathoracic cavity, including: 1) dual-pulse ADS therapy, during which a first ADS pulse is delivered during a diastolic phase of a cardiac cycle and a second ADS pulse is delivered during a systolic phase, 2) paired-pulse ADS therapy, during which a first ADS pulse is delivered, closely followed by a second ADS pulse, with the second ADS pulse functioning to extend or enhance a phase of a transient, partial contraction of the diaphragm, and 3) multiple-pulse ADS therapy, during which a stream of ADS pulses is delivered, wherein the time between pulses is based on heart rate. Devices, systems and methods also monitor electromyography (EMG) activity of the diaphragm relative to baseline activity to assess the health of a diaphragm subject to ADS therapy and to adjust ADS therapy parameters or sensing parameters.
    Type: Grant
    Filed: November 3, 2022
    Date of Patent: February 27, 2024
    Assignee: VisCardia, Inc.
    Inventors: Peter T. Bauer, Timothy Wheeler
  • Patent number: 11903683
    Abstract: Certain aspects of the present disclosure provide methods, apparatus, and computer-readable media for determining hemodynamic stability in a subject. In one example method, an optical signal is transmitted via at least one optical fiber in a set of one or more optical fibers partially disposed in a heart of the subject, wherein the at least one optical fiber in the set is configured to bend with the mechanical movement of the heart. A reflected portion of the optical signal is received via the at least one optical fiber, wherein changes in at least one parameter of the received reflected portion of the optical signal are indicative of the mechanical movement of the heart. A hemodynamic stability of the heart is determined based on the received reflected portion. Hemodynamic stability of the subject may further be determined based on thermal, ultrasound, and/or impedance signals measured in or near the heart.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: February 20, 2024
    Assignee: CHELAK MEDICAL SOLUTIONS INC
    Inventors: Jie Cheng, Dhanunjaya Lakkireddy
  • Patent number: 11896387
    Abstract: Described herein are methods, devices, and systems that use electrogram (EGM) or electrocardiogram (ECG) data for sleep apnea detection. An apparatus and method detect potential apnea events (an apnea or hypopnea event) using a signal indicative of cardiac electrical activity of a patient's heart, such as an EGM or ECG. Variations in one or more morphological or temporal features of the signal over several cardiac cycles are determined and used to detect a potential apnea event in a measurement period. Checks can then be made for a number of factors which could result in a false detection of an apnea event and if such factors are not present, an apnea event is recorded. Described herein are also methods, devices, and systems for classifying a patient as being asleep or awake, which can be used to selectively enable and disable sleep apnea detection monitoring, as well as in other manners.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: February 13, 2024
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Prakrit Shrestha, Kyungmoo Ryu
  • Patent number: 11896432
    Abstract: A system is provided for augmenting a three-dimensional (3D) model of a heart to indicate the tissue state. The system accesses a 3D model of a heart, accesses two-dimensional (2D) images of tissue state slices of the heart, and accesses source location information of an arrhythmia. The system augments the 3D model with an indication of a source location based on the source location information. For each of a plurality of the tissue state slices of the heart, the system augments a 3D model slice of the 3D model that corresponds to that tissue state slice with an indication of the tissue state of the heart represented by the tissue state information of that tissue state slice. The system then displays a representation of the 3D model that indicates the source location of the arrhythmia and the tissue state of the heart.
    Type: Grant
    Filed: July 25, 2023
    Date of Patent: February 13, 2024
    Inventors: Christopher J. T. Villongco, Adam R. Geronemus, Robert Joseph Krummen
  • Patent number: 11894148
    Abstract: Systems and methods are provided for treating an inflammatory or allergic response associated with a replicating pathogen, such as a virus in the coronaviridae family. The methods include emitting an electrical impulse near a vagus nerve within the patient sufficient to inhibit or reduce an inflammatory or allergic response in the patient, provide relief for bronchoconstriction that results in the tightening of airways and the inability to breath without ventilator support and/or lessen the abnormal blot clotting that develops in some patients. The systems and methods are particularly useful for treating post-COVID conditions or post-acute sequelae of COVID-19 that develop in “long-haul” or COVID patients.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: February 6, 2024
    Inventors: Joseph P. Errico, Bruce J. Simon, Peter Staats, Thomas Errico
  • Patent number: 11890462
    Abstract: A system for stimulating body tissue may include a user interface and a control unit. The control unit may include a processor and non-transitory computer readable medium. The non-transitory computer readable medium may store instructions that, when executed by the processor, causes the processor to identify an electrode combination and determine a threshold charge for use in stimulating the body tissue. The processors identifications and determinations may be based at least partially on input received via the user interface.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: February 6, 2024
    Assignee: Lungpacer Medical Inc.
    Inventors: Matthew J. Gani, Kaitlin Taylor, Viral S Thakkar, Douglas G. Evans
  • Patent number: 11806536
    Abstract: System and methods are provided herein and include a HIS electrode configured to be located proximate to a HIS bundle and to at least partially define a HIS sensing vector. They system includes memory to store program instructions and cardiac activity (CA) signals for a series of beats utilizing a candidate sensing configuration. The candidate sensing configuration is defined by i) the HIS sensing vector and ii) a sensing channel that utilizes sensing circuitry configured to operate based on one or more sensing settings to detect near field and far field activity. The system includes one or more processors that, when executing the program instructions, are configured to analyze the CA signals to obtain an atrial (A) feature of interest (FOI) and a ventricular (V) FOI for the corresponding beats within the series of beats and identify a V-A FOI relation between the A FOIs and the V FOIs across the series of beats.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: November 7, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Aditya Goil, Xiaoyi Min, Wenwen Li, Yun Qiao, Jan O. Mangual-Soto, Carin Folman
  • Patent number: 11717673
    Abstract: A system for stimulating body tissue may include a user interface and a control unit. The control unit may include a processor and non-transitory computer readable medium. The non-transitory computer readable medium may store instructions that, when executed by the processor, causes the processor to identify an electrode combination and determine a threshold charge for use in stimulating the body tissue. The processors identifications and determinations may be based at least partially on input received via the user interface.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: August 8, 2023
    Assignee: Lungpacer Medical Inc.
    Inventors: Matthew J. Gani, Kaitlin Taylor, Viral S. Thakkar, Douglas G. Evans
  • Patent number: 11701510
    Abstract: A blood pump including a housing having an inflow tube defining a major axis spanning through the inflow tube and a flow path spanning along the major axis, a rotor disposed within the inflow tube, the rotor and the inflow tube defining a gap therebetween, a stator surrounding the inflow tube and the rotor, and the housing defining an access conduit spanning through the inflow tube and the stator transverse to the major axis, the access conduit being in communication with the gap.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: July 18, 2023
    Assignee: HeartWare, Inc.
    Inventor: Zoe N. Demou
  • Patent number: 11684791
    Abstract: An active implantable medical device includes a detection electrode and a pulse generator. The pulse generator is configured to collect via the detection electrode at least two EGM signals, combine the EGM signals into two time components, and combine the components into a single 2D parametric characteristic representing the cardiac cycle. During a tachyarrhythmia episode, the device measures stores values of a cycle-to-cycle variation in an amplitude of the at least one of the EGM signals, distributes the amplitude variation values into a plurality of classes, each class corresponding to an amplitude interval, and analyzes a size of each of the plurality of classes to deliver at least one of an indicator of suspicion of an artifact of extracardiac origin or an indicator of a type of tachyarrhythmia selectively as a function of at least one predetermined criterion applied to the distribution of the amplitude variation values.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: June 27, 2023
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 11666265
    Abstract: A hearing device includes: a first microphone configured to provide a first input signal; a first processor unit configured to provide a processed signal based on the first input signal to compensate for a hearing loss of a user of the first hearing device; a receiver configured to output sound based on the processed signal; and a first sensor configured to provide a first sensor signal for detecting an atrial fibrillation condition of the user. An electronic device includes: a communication interface configured to communicate with a hearing device; and a processing unit configured to obtain, via the communication interface, information associated with an atrial fibrillation condition of a user, the information comprising a sensor data transmitted from the hearing device and/or information indicating the atrial fibrillation condition detected based on the sensor data; wherein the accessory device is configured to output a signal indicative of the atrial fibrillation condition.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: June 6, 2023
    Assignee: GN HEARING A/S
    Inventor: Tomasz Goldman
  • Patent number: 11647978
    Abstract: The present disclosure describes systems, methods, and devices to infer changes in pulmonary artery pressure in a subject using Doppler radar. A portable, non-invasive device for non-invasively measuring right ventricular cardiac motion that can be used in a subject's home can infer pulmonary artery pressure changes to increase patient compliance and mitigate the likelihood of heart decompensation. A mobile pulmonary artery pressure monitor can be especially useful to patients with congestive heart failure who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: May 16, 2023
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Xiaomeng Gao, Xiaonan Jiang, Xiaoguang Liu, Dennis Matthews, Saul Schaefer
  • Patent number: 11630765
    Abstract: The subject matter described herein provides systems and techniques to counter a high write amplification in physical memory, to ensure the longevity of the physical memory, and to ensure that the physical memory wears in a more uniform manner. In this regard, aspects of this disclosure include the design of a Flash Translation Layer (FTL), which may manage logical to physical mapping of data within the physical memory. In particular, the FTL may be designed with a mapping algorithm, which uses reinforcement learning (RL) to optimize data mapping within the physical memory. The RL technique may use a Bellman equation with q-learning that may rely on a table being updated with entries that take into account at least one of a state, an action, a reward, or a policy. The RL technique may also make use a deep neural network to predict particular values of the table.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: April 18, 2023
    Assignee: Google LLC
    Inventors: Shashwat Silas, Narges Shahidi, Tao Gong, Manuel Benitez
  • Patent number: 11576603
    Abstract: An apparatus includes data acquisition circuitry and a processor. The data acquisition circuitry is configured to acquire multiple signals using multiple respective electrodes of an array of electrodes coupled to one of an organ of a patient and tissue or a cell culture. The processor is configured to hold a definition of a mixed-norm that is defined as a function of relative positions of the electrodes in the array, and jointly compress the multiple signals in a compressed-sensing (CS) process that minimizes the mixed-norm.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: February 14, 2023
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Shmuel Auerbach, Wouter A Serdijn, Samprajani Rout
  • Patent number: 11540808
    Abstract: Aspects of the technology described herein relate to techniques for guiding an operator to use an ultrasound device. Thereby, operators with little or no experience operating ultrasound devices may capture medically relevant ultrasound images and/or interpret the contents of the obtained ultrasound images. For example, some of the techniques disclosed herein may be used to identify a particular anatomical view of a subject to image with an ultrasound device, guide an operator of the ultrasound device to capture an ultrasound image of the subject that contains the particular anatomical view, and/or analyze the captured ultrasound image to identify medical information about the subject.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: January 3, 2023
    Assignee: BFLY Operations, Inc.
    Inventors: Daniel Nouri, Alex Rothberg, Matthew de Jonge, Jimmy Jia, Jonathan M. Rothberg, Michal Sofka, David Elgena, Mark Michalski, Tomer Gafner, Abraham Neben
  • Patent number: 11534108
    Abstract: A wireless wearable sensor device, system, method, and non-transitory computer readable medium for screening for structural heart disease based on electrocardiogram, phonocardiogram, and/or accelerometer signals on a patient's skin surface.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: December 27, 2022
    Assignee: VITAL CONNECT, INC.
    Inventors: Gabriel Nallathambi, Ben Alexander, Nandakumar Selvaraj
  • Patent number: 11524163
    Abstract: A neuromodulation system and method of providing sub-threshold modulation therapy. Electrical modulation energy is delivered to a target tissue site of the patient at a programmed intensity value, thereby providing therapy to a patient without perception of stimulation. In response to an event, electrical modulation energy is delivered at incrementally increasing intensity values. At least one evoked compound action potential (eCAP) is sensed in a population of neurons at the target tissue site of the patient in response to the delivery of the electrical modulation energy at the incrementally increasing intensity values. One of the incrementally increased intensity values is selected based on the sensed eCAP(s). A decreased intensity value is automatically computed as a function of the selected intensity value. Electrical modulation energy is delivered to the target tissue site of the patient at the computed intensity value, thereby providing sub-threshold therapy to the patient.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: December 13, 2022
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Tamara C. Baynham, Jordi Parramon
  • Patent number: 11504048
    Abstract: Techniques are disclosed for detecting arrhythmia episodes for a patient. A medical device may receive one or more sensor values indicative of motion of a patient. The medical device may determine, based at least in part on the one or more sensor values, an activity level of the patient. The medical device may determine a heart rate threshold for triggering detection of an arrhythmia episode based at least in part on the activity level of the patient. The medical device may determine whether to trigger detection of the arrhythmia episode for the patient based at least in part on comparing a heart rate of the patient with the heart rate threshold. The medical device may, in response to triggering detection of the arrhythmia episode, collect information associated with the arrhythmia episode.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: November 22, 2022
    Assignee: Medtronic Monitoring, Inc.
    Inventors: Niranjan Chakravarthy, Rodolphe Katra
  • Patent number: 11426590
    Abstract: A leadless pacemaker device for providing an intra-cardiac pacing includes processing circuitry configured to generate ventricular pacing signals for stimulating ventricular activity at a ventricular pacing rate, a first sensor configuration receiving a first sense signal, and a second sensor configuration receiving a second sense signal. The processing circuitry derives, in a first sensing state, atrial events from the first sense signal for controlling the ventricular pacing rate based on the atrial events. The processing circuitry switches, based on at least one switching criterion, from the first sensing state to a second sensing state in which the processing circuitry derives atrial events from the second sense signal. The second sense signal is received by the second sensor configuration for detection of atrial events and the second sensor configuration is a motion sensor or a sound sensor. A method for operating the pacemaker device is also provided.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: August 30, 2022
    Assignee: BIOTRONIK SE & Co. KG
    Inventors: Madeline Anne Midgett, R. Hollis Whittington, Ravi Kiran Kondama Reddy, Christopher Jones, Shayan Guhaniyogi, Dirk Muessig, Larry Stotts
  • Patent number: 11419575
    Abstract: The present invention relates to an apparatus (1) comprising a signal processor (2) for processing measurement signals (3) from a motion-mode ultrasound measurement and a rendering device (4) coupled to a processor (2) for rendering a one-dimensional representation (40) along a temporal axis (41) indicative of a property within a tissue. The values (42) in the one-dimensional representation (40) are derived on the basis of measured values in an observation window (12, 22, 32) defined on an M-mode ultrasound image (10), a tissue velocity image (20) or a strain rate image (30).
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: August 23, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Caifeng Shan, Godefridus Antonius Harks, Harm Jan Willem Belt
  • Patent number: 11410768
    Abstract: A system that comprises a memory device storing instructions, and a processing device communicatively coupled to the memory device. The processing device executes the instructions to: receive user data obtained from records associated with a user; generate a modified treatment plan based on the user data; and send, to a treatment apparatus accessible to the user, the modified treatment plan, wherein the modified treatment plan causes the treatment apparatus to update at least one operational aspect of the treatment apparatus, and update at least one operational aspect of at least one other device communicatively coupled to the treatment apparatus.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: August 9, 2022
    Assignee: ROM TECHNOLOGIES, INC.
    Inventors: Steven Mason, Daniel Posnack, Peter Arn, Wendy Para, S. Adam Hacking, Micheal Mueller, Joseph Guaneri, Jonathan Greene
  • Patent number: 11376430
    Abstract: Auricular nerve stimulation techniques for addressing patient disorders, and associated systems and methods. A representative system includes a signal generator having instructions to generate an electrical therapy signal, at least a portion of the electrical therapy signal having a frequency at or above the patient's auditory frequency limit, an amplitude in an amplitude range from about 0.1 mA to about 10 mA, and a pulse width in a pulse width range from 5 microseconds to 30 microseconds. The system further includes at least one earpiece having a contoured outer surface shaped to fit against the skin of the patient's external ear, external ear canal, or both, the at least one earpiece carrying at least two transcutaneous electrodes positioned to be in electrical communication with the auricular innervation of the patient, e.g., the auricular vagal nerve.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: July 5, 2022
    Assignee: Nesos Corp.
    Inventors: Vivek K. Sharma, Konstantinos Alataris, Gary Heit, Jason Sutor, Pankaj Sunkeri
  • Patent number: 11350832
    Abstract: In part, the disclosure relates to computer-based methods, and systems suitable for evaluating a cardiac system using a diagnostic metric such as a pressure value-based ratio. Selection of a subset or portion of a cardiac cycle is avoided in one embodiment to increase reliability and usability of a diagnostic ratio and parameters described herein. In one embodiment, a minimum or a relative extrema of a series of diagnostic metrics plotted on a per cycle basis are used to inform diagnosis of a stenosis or other intravascular event or phenomena.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: June 7, 2022
    Assignee: ST. JUDE MEDICAL COORDINATION CENTER BVBA
    Inventor: Johan Svanerudh
  • Patent number: 11338076
    Abstract: A system for controlling a fluid procedure comprising a reusable separation apparatus controlled by a microprocessing controller. A sterile circuit is configured to associate with the reusable separation apparatus and provide a first fluid flow path in association with a pressure sensor in communication with the controller and a first pump configured to transmit pulsatile pressure signals to the pressure sensor during operation in association with the first fluid flow path. The reusable apparatus and the controller are configured to receive from the pressure sensor pressure signals comprising the pulsatile pressure signals, perform a frequency analysis of the pressure signals received by the pressure sensor over a time duration, derive a first rotation rate of the first pump or a first fluid flow rate at the first pump from the frequency analysis, and provide a response action based on the first rotation rate or the first fluid flow rate.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: May 24, 2022
    Assignee: Fenwal, Inc.
    Inventors: Benjamin E. Kusters, Kyungyoon Min
  • Patent number: 11321967
    Abstract: The present invention discloses a method and system for obtaining and tracking motions and gestures of a body part (e.g. a hand) of a user, by using antennas worn on the body (e.g. on a wrist band). The antennas may be near-field antennas which transmit and receive short-range electromagnetic fields. The electromagnetic fields may be modified by interaction with the body part, depending on the exact position of the body part. The modified electromagnetic field may be received by the antennas. The received signal may be processed, to provide additional spatial information (e.g. beamforming). The processed signal may be interpreted by pattern recognition (e.g. neural network, database table). The pattern recognition may be trained using labeled pair data (e.g. known hand positions and corresponding processed signals).
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: May 3, 2022
    Inventor: Xiao Hu
  • Patent number: 11318313
    Abstract: This document discusses, among other things, systems and methods to determine a response between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), across a set of stimulation signals provided to the subject at different AVD intervals, and determining one or more cardiac resynchronization therapy (CRT) parameters using an inflection point of the determined response.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: May 3, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Yinghong Yu, Krzysztof Z. Siejko, Qi An
  • Patent number: 11311731
    Abstract: This document discusses, among other things, systems and methods to determine a response curve between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), to a set of stimulation signals provided to the subject at different AVD intervals. In certain examples, one or more cardiac resynchronization therapy (CRT) parameters can be determined for the subject using the determined response curve.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: April 26, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Yinghong Yu, Krzysztof Z. Siejko, Qi An
  • Patent number: 11285327
    Abstract: This document discusses, among other things, systems and methods to receive physiologic information from a patient during different first and second pacing periods having respective, different first and second atrioventricular (AV) delays, determine first and second physiologic parameters using respective received physiologic information from the first and second pacing periods, and adjust the first AV delay using the determined first and second physiologic parameters, wherein the second AV delay is longer than the first AV delay.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: March 29, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Stephen J. Hahn, Pramodsingh Hirasingh Thakur, Qi An, Viktoria A. Averina, Krzysztof Z. Siejko, Ramesh Wariar
  • Patent number: 11276483
    Abstract: Systems, methods, and apparatus are disclosed aggregating at least two of vital signs data, diagnostic test results, medical data, and user parameters into a single medical record. In one example, a method may include periodically receiving vital signs data and/or diagnostic test results performed on a user; periodically receiving medical data in response to a medical examination of the user performed by a health care practitioner; receiving user parameters about the user; aggregating the vital signs data and/or diagnostic test results, the medical data, and the user parameters into a single medical record; associating the single personal medial record with the user; and storing the single personal medial record into a database of personal medical records. Life expectancy can be calculated. Data aggregation can be performed over time for comparison in real time to medical standard values allowing the user to set personal goals towards greater life expectancy.
    Type: Grant
    Filed: January 22, 2017
    Date of Patent: March 15, 2022
    Assignee: HEALTHY.IO LTD.
    Inventors: Walter De Brouwer, Alexander Cristoff, Scott Thomas
  • Patent number: 11260234
    Abstract: A pacemaker is configured to operate in an atrial synchronous ventricular pacing mode and, after expiration of a conduction check time interval, switch to an asynchronous ventricular pacing mode that includes setting a ventricular pacing interval to a base pacing rate interval. The pacemaker is further configured to determine when atrioventricular block detection criteria are satisfied during the asynchronous ventricular pacing mode and, responsive to the atrioventricular block detection criteria being satisfied, switch back to the atrial synchronous ventricular pacing mode.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: March 1, 2022
    Assignee: Medtronic, Inc.
    Inventors: Juliana E. Pronovici, James W. Busacker, Keelia Doyle, Vincent P. Ganion, Greggory R. Herr, Todd J. Sheldon, Vincent E. Splett
  • Patent number: 11260216
    Abstract: A ventricularly implantable medical device that includes a sensing module that is configured to detect an artifact during ventricular filling and to identify an atrial event based at least on part on the detected artifact. Control circuitry of the implantable medical device is configured to deliver a ventricular pacing therapy to a patient's heart, wherein the ventricular pacing therapy is time dependent, at least in part, on the identified atrial event.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: March 1, 2022
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Jeffrey E. Stahmann, Keith R. Maile, Krzysztof Z. Siejko, Allan Charles Shuros, William J. Linder, Benjamin J. Haasl, Michael J. Kane, Brendan Early Koop
  • Patent number: 11241158
    Abstract: Some embodiments of the present disclosure discuss an apparatus comprising a transceiver configured to generate and/or receive radio frequency (RF) electromagnetic signals, one or more antennae configured to radiate the generated RF electromagnetic signals toward a surface and to output signals corresponding to received reflections of the RF electromagnetic signals, and a processing circuitry configured to process the received reflections and/or the output signals so as to determine change in position of the apparatus with respect to the surface. The apparatus may be incorporated into a wearable garment and/or an adhesive patch, and it may be attached to an outer surface of a human or an animal body.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: February 8, 2022
    Assignee: ZOLL MEDICAL ISRAEL LTD.
    Inventors: Gil Arditi, Roman Vaistikh, Uriel Weinstein
  • Patent number: 11213670
    Abstract: A medical device system includes a cardiac electrical stimulation device and a ventricular assist device (VAD). The cardiac stimulation device and the VAD are capable of communication with each other to confirm detection of cardiac events.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: January 4, 2022
    Assignee: Medtronic, Inc.
    Inventor: Mark L. Brown
  • Patent number: 11207537
    Abstract: A subcutaneous implantable cardioverter-defibrillator (S-ICD) comprising shocking electrodes configured to reduce the defibrillation threshold. The S-ICD may include a canister housing a source of electrical energy, a capacitor, and operational circuitry that senses heart rhythms and an electrode and lead assembly. The electrode and lead assembly may comprise a lead, at least one sensing electrode, and at least one shocking electrode. The at least one shocking electrode may extend over a length in the range of 50 to 110 millimeters and a width in the range of 1 to 40 millimeters.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: December 28, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Andrew L. De Kock, G. Shantanu Reddy, Robert D. Brock, II, Stephen J. Hahn, Brendan E. Koop, Moira B. Sweeney, Wyatt K. Stahl
  • Patent number: 11202908
    Abstract: In some examples, electrical stimulation is delivered to a patient such that selective termination of the stimulation causes a therapeutic effect in the patient after termination of the electrical stimulation to the patient. The electrical stimulation may be insufficient to produce a desired therapeutic effect in the patient during stimulation, but sufficient to induce a post-stimulation desired therapeutic effect following termination of the stimulation. In some examples, the electrical stimulation may be sub-threshold electrical stimulation. In some examples, the desired therapeutic effect may alleviate bladder dysfunction, bowel dysfunction, or other disorders. The stimulation may be selectively terminated in response to one or more therapy trigger events to induce the post-stimulation therapeutic effect.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: December 21, 2021
    Assignee: Medtronic, Inc.
    Inventors: Xin Su, Dwight E. Nelson
  • Patent number: 11197617
    Abstract: A system and method for hemodynamic dysfunction detection may include at least one sensor configured to received one or more signals from a patient, a computing device in data communication with the at least one sensor, a computer-readable storage medium in communication with the computing device, an input device, and an output device. The system may include computer readable instructions to cause the system to receive at least one signal in the time domain from the sensor, determine at least one metric in the frequency domain from the at least one signal in the time domain, and determine the cardiovascular state of the patient from a combination of the at least one metric in the frequency domain and information contained in at least one database of cardiovascular states. The system may also notify a user of a immanent patient cardiovascular event and recommend one or more interventions to mitigate it.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: December 14, 2021
    Assignee: Intelomed, Inc.
    Inventors: Jan Berkow, Anne Brumfield
  • Patent number: 11191959
    Abstract: The invention provides a system for inhibition or treatment of an aberrant neurological event in a subject. The system comprises: one or more detectors; a controller; and one or more stimulators of the vagus nerve. The invention also provides a method for treating and preventing epileptic seizures and the onset or pre-onset of epileptic seizures. The method includes the steps of: collecting signals from each of one or more detector indicating the presence of a repetitive movement; analyzing signals received from the one or more detector to determine the intensity of the stimulation of the auricular branch of the vagus nerve (ABVN) required to control, moderate or prevent current and future repetitive movements; and when required, signaling one or more stimulator to stimulate the ABVN so that the repetitive motion ceases using the determined stimulation intensities.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: December 7, 2021
    Assignee: COGNIGUARD MEDICAL HOLDINGS LIMITED
    Inventors: Tamir Ben-David, Nimrod Kadim, Shmuel Glasberg, Ra'anan Gefen
  • Patent number: 11160495
    Abstract: The present invention relates to a sleep apnea monitoring system for monitoring the sleeping state of a user by means of impedance tomographic image information about the properties of biological tissue and biological signals of the user's body parts to be monitored. The present invention can be manufactured into a very simple portable device and thus enables monitoring during natural sleep at home. Therefore, the present invention enables utilization of obtained information during a sleeping state for diagnosis of and therapeutic plans for sleep apnea.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: November 2, 2021
    Assignee: BiLab Co., Ltd.
    Inventors: Eung Je Woo, Tong In Oh
  • Patent number: 11158179
    Abstract: A system for determining that a monitored person has experienced an event wherein the event is detrimental to the monitored person. The system comprises a first sensing component for producing a first sensed parameter value representative of a first sensed condition of the monitored person and a second sensing component activated responsive to the first sensed parameter value for producing a second sensed parameter value representative of a second sensed condition. A detecting component receives the first and second sensed parameter values for determining that the monitored person has experienced the event.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: October 26, 2021
    Assignee: NXT-ID, INC.
    Inventor: David Tunnell
  • Patent number: 11097106
    Abstract: An implantable neurostimulator-implemented method for managing tachyarrhythmias through vagus nerve stimulation is provided. An implantable neurostimulator, including a pulse generator, is configured to deliver electrical therapeutic stimulation in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers of a patient's cervical vagus nerve. Operating modes of the pulse generator are stored. A maintenance dose of the electrical therapeutic stimulation is delivered to the vagus nerve via the pulse generator to restore cardiac autonomic balance through continuously-cycling, intermittent and periodic electrical pulses. A restorative dose of the electrical therapeutic stimulation is delivered to prevent initiation of or disrupt tachyarrhythmia through periodic electrical pulses delivered at higher intensity than the maintenance dose.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: August 24, 2021
    Assignee: LivaNovaUSA, Inc.
    Inventors: Imad Libbus, Badri Amurthur, Bruce H. KenKnight
  • Patent number: 11089958
    Abstract: Systems and methods for managing machine-generated medical events detected from one or more patients are described herein. A medical event management system includes an event analyzer circuit to detect a medical event using physiological data from a patient-triggered episode acquired from a medical device. The event analyzer circuit determines a confidence score of the medical event detection, and generates an alignment indicator indicating a degree of concordance between the detected medical event and the information about the patient-triggered episode. The system assigns priority information to the patient-triggered episode using the generated alignment indicator and the confidence score of the detection. An output circuit can output the received physiological information to a user or a process according to the assigned priority information.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: August 17, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Amy Jean Brisben, Qi An, Pramodsingh Hirasingh Thakur, David J. Ternes, JoAnna Trapp Simpson, Viktoria A. Averina, Deepa Mahajan, Sunipa Saha, Krzysztof Z. Siejko
  • Patent number: 11071476
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: July 27, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Patent number: 11013914
    Abstract: An implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction is provided. A stimulation therapy lead includes helical electrodes configured to conform to an outer diameter of a cervical vagus nerve sheath, and a set of connector pins electrically connected to the helical electrodes. A neurostimulator includes an electrical receptacle into which the connector pins are securely and electrically coupled. The neurostimulator also includes a pulse generator configured to therapeutically stimulate the vagus nerve through the helical electrodes in alternating cycles of stimuli application and stimuli inhibition that are tuned to both efferently activate the heart's intrinsic nervous system and afferently activate the patient's central reflexes by triggering bi-directional action potentials.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: May 25, 2021
    Assignee: LivaNova USA, Inc.
    Inventors: Imad Libbus, Badri Amurthur, Bruce H. Kenknight
  • Patent number: 11013416
    Abstract: An earphone includes a loudspeaker, a microphone, a housing supporting the loudspeaker and microphone, and an ear tip surrounding the housing and configured to acoustically couple both the loudspeaker and the microphone to an ear canal of a user, and to acoustically close the entrance to the user's ear canal. A processor receives input audio signals from the microphone, detects peaks having a frequency of around 1 Hz in the input audio signals, based on the detected peaks, computes an instantaneous heart rate, measures a frequency of an oscillation within the instantaneous heart rate, and based on the frequency of the oscillation, computes a rate of respiration.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: May 25, 2021
    Assignee: Bose Corporation
    Inventors: Romain Kirszenblat, Mikhail Ioffe
  • Patent number: 10987059
    Abstract: A device comprising a three-dimensional polymeric element and an electronic element integrated with the polymeric element is disclosed. The electronic element is made up of one or more electrode(s) each individually connectable to a measuring device and/or a controller, and each independently having a thin electrically-isolating layer deposited thereon such that the electrode is exposed to an environment surrounding the electrode at one or more pre-determined locations over the electrode. The device can include cells and/or tissue and/or a therapeutically active agent incorporated within the polymeric material. Processes of fabricating the device, systems for operating the device and methods utilizing same are also disclosed.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: April 27, 2021
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Tal Dvir, Yosi Shacham-Diamand, Ron Feiner, Leeya Engel
  • Patent number: 10987004
    Abstract: The invention provides a body-worn monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling). The body-worn monitor processes this information to minimize corruption of the vital signs by motion-related artifacts. A software framework generates alarms/alerts based on threshold values that are either preset or determined in real time. The framework additionally includes a series of ‘heuristic’ rules that take the patient's activity state and motion into account, and process the vital signs accordingly. These rules, for example, indicate that a walking patient is likely breathing and has a regular heart rate, even if their motion-corrupted vital signs suggest otherwise.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: April 27, 2021
    Assignee: SOTERA WIRELESS, INC.
    Inventors: Devin McCombie, Matt Banet, Marshal Dhillon, Jim Moon
  • Patent number: 10967188
    Abstract: Systems and methods for controlling blood pressure by controlling atrial pressure and atrial stretch are disclosed. In some embodiments, a stimulation circuit may be configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient, and at least one controller may be configured to execute delivery of one or more stimulation patterns of stimulation pulses to the at least one cardiac chamber, wherein at least one of the stimulation pulses stimulates the heart such that an atrial pressure resulting from atrial contraction of an atrium overlaps in time a passive pressure build-up of the atrium, such that an atrial pressure of the atrium resulting from the stimulation is a combination of the atrial pressure resulting from atrial contraction and the passive pressure build-up and is higher than an atrial pressure of the atrium would be without the stimulation, and such that the blood pressure of the patient is reduced.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: April 6, 2021
    Assignee: BackBeat Medical, LLC
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Patent number: 10893813
    Abstract: Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: January 19, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Imad Libbus, Krzysztof Z. Siejko, Marina V. Brockway, Robert J. Sweeney
  • Patent number: 10881862
    Abstract: Methods and/or devices may be configured to estimate right ventricular-timings from left ventricular (LV) sensing times for adaptive cardiac therapy using DDD/VDD LV pacing without using a right ventricular (RV) lead. One embodiment employs a subcutaneous device (SD) in a patient and a leadless pacing device (LPD) coupled to a patient's heart. Heart activity including atrial and ventricular events are sensed from the patient's heart using the SD. Left ventricular events (LVS) are sensed using the LPD. The SD is used to determine whether cardiac resynchronization pacing therapy (CRT pacing) is appropriate based upon the heart activity sensed by the SD. The SD is further configured to determine timing of CRT pacing pulses for delivery to cardiac tissue through the LPD.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: January 5, 2021
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: RE49122
    Abstract: A method of detecting an early onset of neurocardiogenic syncope in a patient uses respiratory functions as a predictor of the syncope. According to the method, at least one sample of baseline minute ventilation, tidal volume and respiratory rate of the patient is obtained. The detection unit is set to detect an increase in tidal volume and in minute ventilation over a predetermined respiratory period. The detecting unit also detects any rate of change in respiratory rate and sends a signal to a microprocessor to determine whether the increase in minute ventilation is a sole function of increased tidal volume. The impending syncope is diagnosed if variance in respiratory rate is less than 25% in relation to the sampled baseline during the predetermined period of time.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: July 5, 2022
    Assignee: PHYSIOVOYANCE, LLC
    Inventor: Paul Lelorier