Abstract: A method for expressing a homeostatic function activating gene, comprising a step of applying a thermal stimulus, which is lower than 50 degrees Celsius, to at least a stimulus application origin part, which is a part between first and second toes of left or right foot sole, and which is located at an intersection of an extended line of a medial edge and a vertical line of the medial malleolus, by using an electric type warm temperature heating stimulus apparatus, thereby increasing a blood volume.

Abstract: Described herein are devices, systems, and methods for delivering phototherapy to a subject. A phototherapy light engine is combined with other components to form a phototherapy system that provides phototherapy treatment to a subject. A phototherapy system may be implemented as a hand held system comprising the light engine that is configured to communicate with a remote computing device.

Abstract: Described herein are user-wearable devices that include an optical sensor, and methods for use therewith. In certain embodiments, an optical sensor of a user-wearable device (e.g., a wrist-worn device) is used to detect blue light that is incident on the optical sensor and to produce a blue light detection signal indicative thereof, and thus, indicative of the response of the user's intrinsically photosensitive Retinal Ganglion Cells (ipRGCs). In dependence on the blue light detection signal, there is a determination of a metric indicative of an amount of blue light detected by the optical sensor. The metric is compared to a corresponding threshold, and a user notification is triggered in dependence on results of the comparing, wherein the user notification informs a person wearing the user-wearable device to adjust their exposure to light.

Abstract: A system for controlling a treatment device generates a graphical interface that visually prompts a user in a step-wise fashion to use the treatment device to perform a process of forming a pattern of lesions that extends both circumferentially and axially in different levels in a body region. The graphical interface displays for the user a visual record of the progress of the process from start to finish and guides the user so that so that individual lesions desired within a given level are all formed, and that a given level of lesions is not skipped.

Abstract: A method of treating cancer. The method includes introducing an effective amount of an oxidative catalyzing agent including titanium oxide, zinc oxide, zirconium oxide, tungsten oxide or tin oxide into a biological entity, and irradiating the biological entity with a ray. The oxidative catalyzing agent produces hydroxyl or hydrogen peroxide radicals after irradiation with the ray thereon.

Abstract: A hand held, home use, device for treatment of skin, comprising: a housing exhibiting an opening therein and forming an air cavity when the opening is placed in contact with the skin; an incandescent type bulb secured within the housing and arranged to irradiate the skin with infra-red radiation and heat air within the formed air cavity, the incandescent type bulb exhibiting a filament; and a control and driving circuitry in electrical communication with the incandescent type bulb and operative to output a train of pulses exhibiting an on time when current is driven through the filament and an off time when current is not driven through the filament, the off time greater than or equal to the on time, the off time being of a duration such that the infra-red radiation irradiating the skin falls, during the off time, to no less than 25% of its maximum value.

Abstract: An oscillating photo light therapy device includes a base and a light emitting unit pivotally mounted to the base. The light emitting unit is provided with at least one light emitting source. A movement imparting mechanism is provided for displacing the light emitting unit relative to the base along an oscillating motion, wherein the light source emits at different angles towards the user's body.

Abstract: A device and method for preventing and treating bedsores on a lying patient. The device uses both a fan and a UV light source. The fan dries the skin while the UV light source aids in drying the patient as well as killing harmful pathogens. The device is adjustable so the air and UV light can be directed at various angles and from different heights, to a patient in different positions, prone, supine, and laying on side.

Abstract: Due to the lack of internal anatomic detail with traditional magnetic resonance imaging, preoperative stereotactic planning for the treatment of tremor usually relies on indirect targeting based on atlas-derived coordinates. To overcome such disadvantages, a method is provided that allows for deep brain stimulation targeting based on brain connectivity. For example, probabilistic tractography-based thalamic segmentation for deep brain stimulator (DBS) targeting is suitable for the treatment of tremor.

Abstract: The present invention generally relates to a method of using light treatment supporting specific cell types in a subject. Specifically, the present invention relates to methods for stimulating the proliferation, migration, differentiation and survival of cell using specific parameter of lights. These methods are particularly useful in the cellular regeneration and replacement in a tissue injury, such as CNS or PNS injury, and in transplantation of organs, tissues and cells.

Abstract: A circumaural earphone and a decorating strap thereof are provided. The circumaural earphone includes two earphone cups, a main strap, a decorating strap, a photosensitive switch, a power supplier and a light emitter. Two ends of the main strap are connected with the two earphone cups. Two ends of the decorating strap are detachably connected with the two earphone cups or the main strap. The photosensitive switch is disposed in one of the two earphone cups, the main strap or the decorating strap. The power supplier is disposed in one of the two earphone cups, the main strap or the decorating strap. The light emitter is disposed in the decorating strap and electrically connected with the power supplier through the photosensitive switch.

Abstract: Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly comprising a first wall to which the lamps are affixed thereto and a second wall, closer to the patient, spaced from the first wall wherein the lamps are recessed relative thereto. The second wall comprises a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs on the first wall for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed between the first and second wall so that the reflective surface is relatively smooth and seamless towards the patient. The walls may include an eye slot. The device is mounted to the user with a frame comprising an eyeglass frame or goggles including lenses for shielding the user's eyes from lamp radiation.

Abstract: Device for external medical treatment using light, including a light emitting element arranged to abut against or near the body of an individual and a drive device for the light emitting element, which includes light emitting diodes. The drive device controls the light emitting element to emit light of one or several wavelengths during one or several predetermined times, and to emit the light in a pulsating manner. The light emitting element includes a cover and a light emitting diode plate, supporting the light emitting diodes positioned thereon with a certain distance between two adjacent light emitting diodes. The drive device is arranged to control the light emitting element to emit pulsating light with a pulse length which lies within an interval of about 60% to 90% of the time between the respective start edge of two consecutive pulses, and to vary the length of the pulses over time.

Abstract: Device for external medical treatment using light, including a light emitting element arranged to abut against or near the body of an individual and a drive device for the light emitting element, which includes light emitting diodes. The drive device controls the light emitting element to emit light of one or several wavelengths during one or several predetermined times and to emit the light in a pulsating manner. The light emitting element includes a cover and a light emitting diode plate, supporting the light emitting diodes positioned thereon with a certain distance between two adjacent light emitting diodes. The device emits light in two or several series with increasing pulse frequencies F1, F2, Fn, where F1 is a fundamental frequency and where F2 and Fn are multiples of the fundamental frequency. The device emits a pulse repetition frequency that varies about the respective frequency F1, F2 and Fn.

Abstract: Methods, devices and systems for delivering light therapy to human or non-human animal subjects. Included are shapeable light therapy devices which are formable into different shapes suitable for delivery of therapeutic light to different regions of the subject's body and will retain the desired shape without a need for the use of a strap or other shape-retaining apparatus. Also included are light therapy devices that, in at least some modes of operation, deliver light that is not visible to the human eye and which include indicator(s) to indicate to a user and/or to the subject being treated when non-visible light is actually being emitted.

Abstract: A cellulite and fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing green light at approximately 529.6 nm, and at approximately 48,860 Lux, measurable at the array.

Abstract: A device for emitting light by means of LEDs of the continuous and pulsed type for aesthetic and therapeutic treatments, of the type comprising an electric power supply circuit which is connected to a respective external control and management unit and at least one LED controlled by the circuit and oriented toward a surface that is intended to face the skin of the patient in conditions for use, the device having a platelike shape; the at least one LED being arranged on a laminar accommodation element that is arranged at a constant distance from the surface intended to face the skin of the patient in conditions for use; the electric circuit comprising at least one apparatus for adjusting the electric power supply values of the at least one LED controlled by the control and management unit in order to set the power of the light beam emitted by the at least one LED.

Abstract: Switching power supplies made in accordance with the disclosed technology drive flash lamps of dermatologic treatment devices to emit a sequence of relatively small light pulses that are aligned with particular locations within the waveform of the AC line source. Such power supplies not only enable sufficient light energy in aggregate to therapeutically heat target chromophores in a skin region without causing undesired damage to surrounding tissue, but also provide the added benefit that the corresponding electrical energy need not be substantially drawn from any charged capacitor. The disclosed power supply further compensates for performance degradation of the flash lamps during their usable life, by modifying its operation based on predetermined values that are indicative of flash lamp aging/efficiency characteristics. The flash lamps and their associated stored values are preferably incorporated into a replaceable cartridge that facilitates user maintenance of the dermatologic treatment device.

Abstract: Devices with high-power light-emitting diodes (LEDs) for use in human and/or animal phototherapy applications are disclosed. The phototherapy device includes a number of select LEDs for emitting a desired range or ranges of wavelengths of high intensity light for use in treatment. Additionally, the phototherapy treatment includes one or more methods for providing a treatment appropriate to the condition desired to be treated. The phototherapy device provides a diversity of high power light settings, intensity levels, and selectable time intervals.

Abstract: The invention relates to a device for the stimulation of thermal receptors in the skin of a patient by means of thermal stimuli. The device comprises a plurality of noninvasive stimulation units for irradiating the skin of the patient with electromagnetic radiation, wherein thermal stimuli are produced by absorption of the electromagnetic radiation in the skin of the patient and the wavelength range of the electromagnetic radiation emitted by the stimulation units can be adjusted. The device also comprises a control unit for controlling the stimulation units.

Abstract: A therapeutic laser with a source of pulsed electromagnetic radiation, a control device for controlling the intensity and/or the duration of the therapeutic laser applied to the tissue, and a detection device for detecting optoacoustic signals triggered by irradiating the living tissue with the pulsed electromagnetic radiation. The therapeutic laser is characterized by an evaluation device that acts on the control device and is used for calculating a degree of quality B(t) from the optoacoustic signals detected by the detection device for individual laser pulses applied to a predetermined laser spot and determining a fit function f(t) at a predetermined point in time ?t1, the fit function f(t) approximating the mean curve of B(t) for 0?t??t1. The intensity and/or the irradiation time of the therapeutic laser is defined by the parameters for the predetermined laser spot, the parameters being determined for the fit function f(t).

Abstract: The present invention provides a skin care device with multiple functions. The skin care device includes a main body having a first connecting terminal formed on the upper portion thereof; a plurality of skin care heads individually and detachably combined with the main body, the skin care heads each having a second connecting terminal formed on the lower portion thereof and having at least one of a galvanic current generator, an ultrasonic vibrator, or a near-infrared light emitting diode (LED) installed therein; and a product identification displaying part displays an identification number of the heads or a relevant image of the heads on a display screen when the first connecting terminal and the second connection terminal are connected each other. The skin care device allows users to care their skin effectively through a variety of beneficial functions such as galvanic electric current, ultrasonic vibrations, and near-infrared LED.

Abstract: An irradiation device for irradiating of body parts of a patient is provided, with a carrier system which provides a basic framework of the irradiation device with at least one light head with a light source for the irradiation, and a control element for operating the irradiation device. The irradiation device moreover includes a separate control module that is connected with the carrier system with at least one control for controlling the at least one light head. Innovative assembly and connection arrangements aid rapid and secure positioning.

Abstract: Systems and methods of ophthalmologic or ocular phototherapy treatment are provided herein. In some embodiments, the systems and methods of ophthalmic or ocular phototherapy treatment comprise applying a treatment light beam in a predetermined wavelength or wavelength range corresponding to gold (yellow to orange), red, or at least part of both the gold and red visible light wavelength ranges to at least a portion of an eye. The treatment light beam may be applied to an entire eye. In some embodiments, the selected treatment area is irradiated with light in the selected gold and/or red wavelength range at a predetermined dose for a selected time period as a primary treatment in order to treat various eye conditions and reduce eye pain or discomfort, or help to promote eye wound healing following injury or surgery, or as a secondary treatment to augment eye treatment using light in different phototherapy treatment ranges.

Abstract: A computer implemented method and apparatus can create an exposure regimen for a user. The regimen can be used to instruct an exposure device to expose the user to light at a wavelength, duration, and intensity, and over one or more days, which is sufficient to alter the user's circadian rhythm. The user may provide one or more preferences which allow the technology to create the exposure regimen sufficient to alter the user's circadian rhythm.

Abstract: A wellness and/or heat blanket has autonomous, optically conductive fibers which are present in a proportion of 40 g/m2 or less, preferably 37 g/m2 or less and in particular approximately 35 g/m2 and/or which constitute a weight proportion of less than 15%, preferably less than 10% and in particular 8% or less.

Abstract: A phototherapy device includes an outlet end to be placed in contact with a person's skin, a heat exchanger, an optical structure arranged between the heat exchanger and the outlet end, and a light source arranged between the heat exchanger and the outlet end, and configured to emit light for delivery to the skin through or adjacent the optical structure. The heat exchanger may include a first heat transfer portion thermally coupled to the light source for dissipating heat from the light source, and a second heat transfer portion thermally coupled to the optical structure for dissipating heat from the optical structure. The first and second heat transfer portions of the heat exchanger may be substantially thermally isolated from each other, e.g., partially or completely physically separated from each other.

Abstract: There are provided an apparatus and a method for blocking abnormal conduction in the cardiac muscle using a photodynamic therapy or for treating arrhythmia. There is provided a catheter ablation apparatus for the treatment of arrhythmia using a photodynamic therapy, comprising a catheter leading a photoradiation unit to an abnormal electrical conduction site or a hyperexcitability occurring site in the cardiac muscle of a test subject in which a photosensitizer is present by administering the photosensitizer beforehand and which causes arrhythmia, means for generating a light ray with which the abnormal electrical conduction site or the hyperexcitability occurring site is irradiated, and means for transmitting the light ray to the abnormal electrical conduction site or the hyperexcitability occurring site, wherein the photosensitizer used is a water-soluble chlorine-based photosensitizer and the light ray used is a light ray having an excitation wavelength equal to that of the photosensitizer.

Abstract: The present invention relates to light applicators, systems comprising light applicators, and methods for their use. One aspect of the invention provides a light applicator configured for contacting a portion of a subject's body surface and controllably applying light irradiation thereto. The light applicator comprises a housing, the housing comprising a treatment plate for contacting the portion of the subject's body surface and having one or more windows. One or more light emitters are disposed inside the light applicator and projecting toward the corresponding one or more windows of the treatment plate. A heat spreader plate is disposed inside the light applicator. One or more heat conducting members thermally connect the treatment plate to the heat spreader plate.

Abstract: A photo-therapy method using a display device is provided. The photo-therapy method includes receiving a viewing time input and a photo-therapy selection input, wherein the viewing time input represents an expected viewing time of a user and the photo-therapy selection input represents a photo-therapy selected by the user. The photo-therapy method further includes calculating a period of a photo-therapy image based on the expected viewing time and a suggested treatment time of the selected photo-therapy, and displaying the photo-therapy image with the calculated period while displaying a normal image.

Abstract: A cosmetic device disposed with a magnetic attraction structure and a replaceable cosmetic assembly is disclosed. The cosmetic device includes a holding unit, a connection part, a cover body, and the cosmetic assembly. The holding unit has a power supply unit and a notch disposed with a first magnetic attraction component and several first connection terminals. The power supply unit electrically connects with the first connection terminals for transmitting electric power. The connection part includes a fixing block disposed with a second magnetic attraction component and several second connection terminals. The second magnetic attraction component and the first magnetic attraction component may attract each other for binding the connection part with the holding unit. The second connection terminals are electrically connected with the first connection terminals.

Abstract: A skin rejuvenation device and method for the cosmetic or anti-aging reduction of wrinkles and other skin conditions is disclosed. The skin rejuvenation device comprises an array of positive and negative electrodes for the delivery of electrical microcurrents in the attoampere to milliampere range, light sources to deliver photonic stimulation and/or transducers to deliver ultrasonic stimulation to the skin and underlying tissues.

Abstract: A display apparatus providing light therapy includes a display panel configured to display an image to a display region based on input image data, and a lens part disposed on the display panel, the lens part configured to focus the image displayed by the display panel toward a first region in a therapy mode, in which the first region is smaller than the display region, and the first region may correspond to a position of a user's face.

Abstract: A radiation device (30) for providing radiation to the skin is described. The radiation device comprises a radiation guide (31) for directing radiation whereby the radiation guide (31) is configured for receiving radiation from at least one radiation source (20) in a side-lit configuration. The radiation device (30) comprises moisture transfer channels (32) inside the radiation guide (31) for enabling moisture transfer from the skin through the radiation guide (31) to the environment. The shape of the walls of the moisture transfer channels (32) is adapted for redirecting radiation in the radiation guide (31) towards the skin.

Abstract: A device (10) for light based skin treatment is provided. The device (10) comprises a light source (18) for providing an incident light beam (21) for treating a skin (30), 18 optical elements for focusing the incident light beam (21) in a focal point (22) inside the skin (30), and a skin interface element (11) for, during use of the device (10), providing optical coupling of the incident light beam (21) from the device (10) into the skin (30). The skin interface element (11) comprises a transparent exit window (12) for allowing the incident light beam (21) to leave the device (10), on top of the exit window (12), a transparent mixture (13) of a polar substance and an apolar substance, and on top of the transparent mixture (13), a transparent foil (14), the transparent foil (14) being more hydrophobic than the exit window (12).

Abstract: A treatment apparatus (10) is used for treatment of parts of a skin (5). The apparatus comprises a radiation source (1) emitting radiation, and a radiator (2) for guiding the emitted radiation to the parts of the skin (5). The parts of the skin (5) comprise skin cells affected by psoriasis. The radiation source (1) emits radiation in a first wavelength range of 400-460 nm, in a second wavelength range of 600-700 nm, or in a first wavelength range of 400-460 nm and a second wavelength range of 600-700 nm.

Abstract: Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising Ring system 1, Ring system 2, Ring system 3, or Ring system 4. Methods of treating disease with phototherapy are also described.

Abstract: A phototherapy device comprises includes a translucent insulating carrier, and an illuminant module disposed inside the translucent insulating carrier, where in the illuminant module comprises a circuit board, a power supply unit, a switch, and at least one light emitting diode, wherein the power supply unit, the switch, and the light emitting diode coupled to the circuit board and electrically connected to each other. Therefore, it is more convenient to carry the phototherapy device due to the volume of the phototherapy device is reduced, and reduces cost effectively. Also, the phototherapy device adopts the SMD (Surface Mount Device) design to be suitable for attaching on the skin, and provides more choice to the consumers.

Abstract: A device for treatment of dermatological lesions includes a gas discharge lamp for generating a plurality of different electromagnetic radiation treatments. A power supply for driving the gas discharge lamp is selectively controlled to drive the gas discharge lamp to output a first electromagnetic treatment when an area of skin being treated has a pigmented lesion, and to drive the gas discharge lamp to output a second electromagnetic treatment when the area of skin being treated has a vascular lesion, where the second electromagnetic treatment has a spectral distribution that is blue-shifted relative to the spectral distribution of the first electromagnetic treatment.

Abstract: A device and method for applying light to the cornea of the eye as, for example, to promote crosslinking of collagen in the cornea for vision correction. The device may include a structure having form and size similar to a conventional contact lens. The structure may include an optically dispersive element such as a mass of an optically dispersive material that may be contained in a cavity of a reflective element. Light applied to the dispersive mass as, for example, by an optical fiber connected to the structure is dispersed in the structure and passes into the cornea. The patient may blink or close the eye during the procedure, which increases patient comfort and aids in maintaining hydration of the cornea.

Abstract: A method for removing tattoos using two laser beams and a multi-photon process is disclosed. A 0.1 to 100 nsec pulse secondary laser beam focused to 108 W/cm2 creates a temporary channel from the skin surface to the tattoo pigment. A 100 fsec pulse main laser beam is then guided through the channel to the pigment and focused to sufficient intensity, i.e., 1012 W/cm2 or more, to initiate a multi-photon process that breaks up the pigment, disrupting its light reflecting properties. The channel allows the main laser beam unobstructed passage to the pigments, resulting in efficient use of the main laser. The pigment fragments escape through the temporary channel or diffuse into the blood stream. A suitably configured Ti/Sapphire laser beam is split into two components, with an uncompressed component used as the secondary laser beam, and a compressed component as the main laser beam.

Abstract: In an aspect of the disclosure, a stimulation device includes a probe attached to a first support. The probe includes at least one grating coupler for coupling light into the probe. The device further includes at least one optical source for providing an optical stimulation signal mounted on a second support, and at least one means for detachably attaching the first support to the second support. The position of the at least one optical source is aligned with the position of the at least one grating coupler to allow light emitted from the at least one optical source to be received by the at least one grating coupler.

Abstract: Methods, devices and systems for delivering light therapy to human or non-human animal subjects. Included are shapeable light therapy devices which are formable into different shapes suitable for delivery of therapeutic light to different regions of the subject's body and will retain the desired shape without a need for the use of a strap or other shape-retaining apparatus. Also included are light therapy devices that, in at least some modes of operation, deliver light that is not visible to the human eye and which include indicator(s) to indicate to a user and/or to the subject being treated when non-visible light is actually being emitted.

Abstract: An oscillating photo light therapy device includes a base and a light emitting unit pivotally mounted to the base. The light emitting unit is provided with at least one light emitting source. A movement imparting mechanism is provided for displacing the light emitting unit relative to the base along an oscillating motion, wherein the light source emits at different angles towards the user's body.

Abstract: A light emitting device to awaken or alert an animal by stimulating the Suprachiasmatic Nucleus in the brain to suppress melatonin secretion and change gene expression in the brain. The device can be programmed for an initiation time, color of light, brightness, frequency of pulsating light, and level of gradual intensity. It has the advantage of being silent, does not to disturb other people sleeping in the same room and user is more cognitively alert.

Abstract: A method and device are presented for providing patient safe light to a wound. The device includes a radiation source producing flora lethal radiation wavelengths, a radiation conduit detachably optically coupled to the radiation source, and a patch remotely located from the radiation source configured to at least partially conform to a surface contour of the wound. The patch includes a flexible panel formed of a radiation transmitting material able to withstand sterilization, including at least one surface with a disturbed surface area configured to emit radiation upon the wound.

Abstract: An aesthetic treatment device and method for treating the skin of a patient, the device comprising at least one of a plurality of arc lamps, each arc lamp provided with a reflector for obtaining a substantially collimated beam; a pulse generator for generating a train of pulses of electrical energy for energizing said at least one of a plurality of arc lamps; a control unit for controlling pulse shape, amplitude, width, frequency and timing, for obtaining controllable spectral output and energy of the collimated beam through an application end of the device to a designated area of skin of the patient. The device can further comprise secondary light sources with different spectrum characteristics than the arc lamp as well as various attachments including a position feedback, material dispenser, skin cooler, and docking station for optical fiber.

Abstract: A retina phototherapy system having a substantially horizontal working surface with an adjustable, ergonomic headrest assembly. A retina phototherapy device is adjustably disposed on the working surface and generally includes laser optics, a camera, a flat screen monitor, and a control joystick. The laser optics are oriented generally in the direction of the headrest assembly and are configurable so as to focus on a retina of a person using the headrest assembly. The camera is generally coaxially disposed with the laser optics and connected to the monitor so as to project an image of the retina treatment area. The control joystick is configured to micro-adjust a position of the retina phototherapy device in relation to the working surface.

Abstract: Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly comprising a first wall to which the lamps are affixed thereto and a second wall, closer to the patient, spaced from the first wall wherein the lamps are recessed relative thereto. The second wall comprises a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs on the first wall for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed between the first and second wall so that the reflective surface is relatively smooth and seamless towards the patient. The walls have a malleable rigidity for flexible adjustability relative to the user. The device is mounted to the user with a frame comprising an eyeglass frame or goggles including lenses for shielding the user's eyes from lamp radiation.

Abstract: A housing containing individual light therapy Light Emitting Diode bulbs that can be adjusted to illuminate up to nine different modes of different colors and different levels of nanometers designed to aid in specific medical conditions and assist in maintaining healthy skin. It is designed to be installed in tanning beds and hot tub products at angles directly aimed at the facial region.