Light Application Patents (Class 607/88)
  • Patent number: 11554048
    Abstract: Systems and methods of treating meibomian and sebaceous gland dysfunction. The methods include reducing oxygen concentration in the environment of one or more dysfunctional meibomian and sebaceous glands, thereby restoring a hypoxic status of one or more dysfunctional meibomian and sebaceous glands. The reducing of the oxygen concentration is accomplished by restricting blood flow to the one or more dysfunctional meibomian and sebaceous glands and the environment of one or more dysfunctional meibomian sebaceous glands. The restricting of the blood flow is accomplished by contracting or closing one or more blood vessels around the one or more dysfunctional meibomian or sebaceous glands. The methods also include giving local or systemic drugs that lead to the generation of hypoxia-inducible factors in one or more dysfunctional meibomian and sebaceous glands.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: January 17, 2023
    Assignee: The Schepens Eye Research Institute, Inc.
    Inventors: David A. Sullivan, Yang Liu
  • Patent number: 11541249
    Abstract: Certain examples involve controlling a circadian impact of a lighting system. For instance, a lighting system includes a first lighting fixture. The first lighting fixture includes at least one lighting element to illuminate a first space and a first controller to control a first light output of the at least one lighting element. Additionally, the lighting system includes a first background circadian system that provides a first modifying factor to the first controller of the first lighting fixture. The first modifying factor is associated with a first circadian impact profile that specifies a first circadian impact level in the first space. Further, the first controller of the first lighting fixture controls the first light output based on the first modifying factor.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: January 3, 2023
    Assignee: ABL IP HOLDING LLC
    Inventors: David P. Ciccarelli, Daniel Aaron Weiss, Benjamin Marshall Suttles
  • Patent number: 11524173
    Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: December 13, 2022
    Assignee: KNOW Bio, LLC
    Inventors: Nathan Stasko, Nicholas William Medendorp, Jr., Gerald H. Negley, Katelyn P. Reighard
  • Patent number: 11523095
    Abstract: An image projection system includes a first transmitter configured transmit pixel light pulses along a transmission path to be projected onto an eye to render a projection image thereon; a second transmitter configured to generate infrared (IR) light pulses transmitted along the transmission path to be projected onto the eye and reflected back therefrom as reflected IR light pulses on a reception path; a coaxial scanning system arranged along the transmission and reception paths; an eye-tracking sensor configured to generate a retina image of the eye based on reflected IR light pulses, and process the retina image to determine a fovea region location of the eye; and a system controller configured to render the projection image based on the fovea region location, wherein the projection image is rendered with a higher resolution in the fovea region and is rendered with a lower resolution outside of the fovea region.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: December 6, 2022
    Assignee: Infineon Technologies AG
    Inventor: Boris Kirillov
  • Patent number: 11504544
    Abstract: A personal therapy compartment includes a base of size to receive a human patient. The compartment includes a bed in the base said bed being made of a light transmissive material. An array of lights mounted is below the bed to transmit light onto a body supported on the bed. A control panel controls at least the wavelength, intensity and pulsation of the light.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: November 22, 2022
    Assignee: VISIBELLE DERMA INSTITUTE, INC.
    Inventor: Steven J. Daffer
  • Patent number: 11497927
    Abstract: A plurality of devices that provide examination/diagnosis and/or treatment benefits to a patient are presented. The device including a plurality of light sources that provide for the emission of light in a plurality of wavelength ranges, wherein the plurality of light sources are activated by a sensor, configured to determine a proximity of the device to a patient, to control an application of a voltage to selected one of the plurality of light sources for a predetermined time period.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: November 15, 2022
    Assignee: Designs for Vision, Inc.
    Inventors: Liviu Steier, Richard E. Feinbloom
  • Patent number: 11497930
    Abstract: A ring has an open top side and side walls that circumscribe a central region for receiving a phototherapy subject. The side walls include a work surface that is configured to receive visible light through the open top side and reflect the visible light toward the central region for phototherapy. The work surface includes a first surface that is a diffuse reflector and a second surface that is a specular reflector.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: November 15, 2022
    Assignee: AG IP HOLDING LLC
    Inventor: Patrick Kenneth Powell
  • Patent number: 11484730
    Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: November 1, 2022
    Assignee: KNOW Bio, LLC
    Inventors: Nathan Stasko, Nicholas William Medendorp, Jr., Gerald H. Negley, Katelyn P. Reighard
  • Patent number: 11479748
    Abstract: A device for DNA repair phototherapy is provided. A method of use for the device to provide DNA phototherapy to damaged DNA is also disclosed.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: October 25, 2022
    Assignee: The Regents of the University of California
    Inventors: Veronica Gomez-Godinez, Michael Berns, Shirli Cohen, Matthew Ono, Daryl Preece
  • Patent number: 11458329
    Abstract: The invention comprises componentry and devices for light therapy application to a patient in need thereof. The present invention relates to controllers for light therapy devices, light delivery elements, light guides, light guide arrangements configured to deliver personalized light therapy to one or more patients, with related componentry, dosage, and configurations of light therapy delivery elements (e.g., bandages, garments, braces, inserts etc.) suitable to deliver light therapy to one or more patient body areas and associated tissues, as well as sensors for monitoring treatment progress and dosage optimization. Methods of delivering light therapy to a patient and treatment of associated medical indications are also set out herein. Personalized LLLT dosage configurations and telemedicine LLLT treatment platforms and systems are also provided herein.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: October 4, 2022
    Inventor: Jack K. Zhang
  • Patent number: 11452808
    Abstract: Devices and methods for collecting and sensing fluid flow are provided.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: September 27, 2022
    Inventors: Robert Gordon Maurice Selby, Arnau Perdigo-Oliveras, Roderick Marcus Van Den Bergh
  • Patent number: 11452883
    Abstract: A hands-free LED device for the treatment of wrinkles and acne, or hair loss, includes a curved housing. Rigid areas contain the LED bulbs. The LED bulbs are interspaced therebetween the flexible areas; such that between each of the rigid LED bulb areas is a flexible area. The rigid LED bulb areas are between the flexible areas. A leg is provided on opposite sides of the housing, The legs being wider at the top of each leg and narrower at the bottom. The number of LED bulbs at each wavelength for treatment of wrinkles are: 126 LED bulbs of 605 nm; 210 LED bulbs of 630 nm, 126 LED bulbs of 660 nm, and 26 LED bulbs of 850 nm. The number of LED bulbs at each wavelength for treatment of acne are 280 LED bulbs at 415 nm and 210 LED bulbs of 630 nm. Hair loss uses 500-700 LED bulbs at 630 nm.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: September 27, 2022
    Inventors: Stephen James Marchese, Chasen James Marchese
  • Patent number: 11446465
    Abstract: Systems and methods for adjusting a user's circadian rhythm are provided. In some embodiments, a system may be configured to obtain information relating to the user's present circadian rhythm and information relating to one or more anticipated times of sleep and/or wakefulness. The system may generate a model for estimating the user's circadian rhythm. The system may also generate a model for estimating the user's homeostatic sleep drive. Based on one or both models, the system may generate instructions for activating the light source to adjust the user's circadian rhythm.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: September 20, 2022
    Assignee: LumosTech, inc.
    Inventor: Biquan Luo
  • Patent number: 11445972
    Abstract: According to various aspects, a new concept of Steady-State Visually Evoked Potential (SSVEP) based Brain-Computer Interface (BCI) is described where brain-computer communication occurs by capturing SSVEP induced by consciously imperceptible visual stimuli integrated into, for example, a virtual scene. These consciously imperceptible visual stimuli are able to convey subliminal information to a computer. In various embodiments, computer based operations can be mapped to visual elements with associated flickering stimuli, and induced SSVEP can be detected when the user focused upon them. In various embodiments, these visual elements can be introduced into existing display without any perceivable change to content being displayed.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: September 20, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Sanjay E. Sarma, Alex Armengol Urpi
  • Patent number: 11446512
    Abstract: An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of first panels or the at least one second panel and configured to irradiate the surface with substantially uniform intensity visible light. The plurality of first panels and the at least one second panel are rotatably connected. The at least one second panel is connected on each side to one of the plurality of first panels. The second panel acts as a “lighted hinge” to reduce or eliminate optical dead spaces between adjacent panels when the illuminator is bent into a certain configuration.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: September 20, 2022
    Assignee: DUSA PHARMACEUTICALS, INC.
    Inventors: Thomas Boyajian, Mark Carota, Brian Mazejka
  • Patent number: 11446513
    Abstract: A method for treating autism. Light energy is applied externally to a patient's scalp on the skull near the frontal lobes. Optionally the light is also applied to the temporal lobes and the base of the brain. The treatment can be enhanced by activating the cranial nerves while the light is applied. In a preferred embodiment the applied light is in the red range and more preferably about of 635 nm±10 nm. In a preferred embodiment, the applied light energy is applied with a pulse frequency or frequencies of 8 Hz, 53 Hz, 73 Hz and 101 Hz. The light can be emitted from the same light emitter or from multiple emitters. Preferably the light is laser light and is emitted as a line from a hand-held laser device, and the line is waved manually across a person's skull in the desired area in a continuous, sweeping manner.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: September 20, 2022
    Assignee: Erchonia Corporation, LLC
    Inventor: Steven C Shanks
  • Patent number: 11439840
    Abstract: A far ultraviolet light application device for killing pathogens on tissue and proximate thereto includes a tube that is to be utilized in a medical procedure. A first fiberoptic cable is engaged to a wall of the tube so that a first end of the first fiberoptic cable is positioned proximate to a first terminus of the tube. The first fiberoptic cable has a second end operationally engaged an ultraviolet C light emitter so that ultraviolet C light is emitted proximate to the first terminus of the tube. The first fiberoptic cable directs the ultraviolet C light from the ultraviolet C light emitter so that the ultraviolet C light impinges upon tissue and pathogens proximate to the first terminus of the tube to inactivate the pathogens.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: September 13, 2022
    Inventor: Joseph McQuirter, Sr.
  • Patent number: 11426600
    Abstract: Photobiomodulation therapy (PBMT) can be applied to a dystrophic muscle to delay dystrophy progression. A light source device can be contacted to a subject's skin proximal to a dystrophic muscle or muscle group. A light signal (with wavelengths from the red to infrared part of the spectrum) can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the dystrophic muscle or muscle group. The light signal is applied for a time sufficient to stimulate a phototherapeutic response in the dystrophic muscle or muscle group.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: August 30, 2022
    Assignee: MULTI RADIANCE MEDICAL
    Inventors: Douglas Johnson, Max Kanarsky, Ernesto Leal-Junior
  • Patent number: 11394226
    Abstract: Devices, systems, and techniques for monitoring the temperature of a device used to charge a rechargeable power source are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. The temperature of an external charging device and/or an implantable medical device may be monitored to control the temperature exposure to patient tissue. In one example, a temperature sensor may sense a temperature of a portion of a device, wherein the portion is non-thermally coupled to the temperature sensor. A processor may then control charging of the rechargeable power source based on the sensed temperature.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: July 19, 2022
    Assignee: Medtronic, Inc.
    Inventors: Peng Cong, Venkat R. Gaddam, David P. Olson, Erik R. Scott, Todd V. Smith, Leroy L. Perz
  • Patent number: 11383095
    Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: July 12, 2022
    Assignee: KNOW Bio, LLC
    Inventors: Nathan Stasko, Nicholas William Medendorp, Jr., Gerald H. Negley, Katelyn P. Reighard
  • Patent number: 11375588
    Abstract: Disclosed herein are system, apparatus, article of manufacture, method and/or computer program product embodiments, and/or combinations and sub-combinations thereof, for a dimmer device including a driver, and a controller communicatively coupled to the driver and to a monitor device. The monitor device can include a camera and is configured to take a plurality of images of the illumination load. The controller provides a control signal that indicates to the driver to adjust power supplied to an illumination load. The control signal is provided in response to a determination that a performance of the illumination load fails to satisfy a predetermined performance indicator. The performance of the illumination load is determined based on information related to the plurality of images of the illumination load taken by the camera of the monitor device. The controller can adjust a dimming level of the illumination load by providing the control signal to the driver.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: June 28, 2022
    Assignee: Roku, Inc.
    Inventor: Gregory Mack Garner
  • Patent number: 11357406
    Abstract: The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: June 14, 2022
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Klaus Fischer, Alexander Neugebauer, Dominik Spether, Markus Enderle
  • Patent number: 11357407
    Abstract: In a photoacoustic apparatus, a light source irradiates an inspection target with pulsed light; a detector detects acoustic waves generated in the inspection target due to interaction of the pulsed light with the inspection target, and outputs detection signals corresponding to the detected acoustic waves; a light-quantity measurement unit measures the quantity of the light output from the light source; and a signal processor obtains information on an inside of the inspection target by using the detection signals output from the detector. The signal processor also corrects intensities of the detection signals so as to suppress variations in intensities of the detection signals caused by a temporal change in the quantity of the light.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: June 14, 2022
    Assignee: Canon Kabushiki Kaisha
    Inventor: Yasuhiro Someda
  • Patent number: 11350625
    Abstract: One aspect of the invention provides a method for preparing a vein graft. The method includes: applying a tissue passivation agent to a resected anatomical vessel; placing the resected anatomical vessel in a chamber; and allowing the tissue passivation agent to cross-link while the resected anatomical vessel is in the chamber.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: June 7, 2022
    Assignee: The General Hospital Corporation
    Inventors: William G. Austen, Jr., Michael C. McCormack, Robert W. Redmond, Irene E. Kochevar
  • Patent number: 11344743
    Abstract: A phototherapy device includes a clothing item. Illuminators are secured to the clothing item and arranged to illuminate at least a portion of a patient wearing the clothing item. The illuminators include light emitting diodes (LEDs) mounted on at least one flexible printed circuit board (PCB). A temperature sensor is secured to the clothing item and positioned to measure a temperature proximate to the patient wearing the clothing item. A control circuit is connected to receive the temperature from the temperature sensor and operative to turn off the illuminators responsive to the temperature exceeding a maximum permitted temperature.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: May 31, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Matthew Lukens Behler, David Hunt, Darrin Paul Milner
  • Patent number: 11338153
    Abstract: Provided is a phototherapeutic apparatus including: a probe that is held and operated by a user and provided with a photo-irradiation unit that performs irradiation with light beams; and a body provided with a control unit that controls the light beams. The body is provided with a read unit that reads a treatment protocol registered in an IC card (mobile memory medium), and a monitor (operation indication unit) that indicates a region to be irradiated with the light beams to the user, the region being set in the treatment protocol, and the control unit causes the monitor to indicate the region to be irradiated and causes the photo-irradiation unit to perform the irradiation with the light beams at a set value set in the treatment protocol. It is possible to perform the irradiation with the light beams in accordance with the treatment protocol and safely use the phototherapeutic apparatus.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: May 24, 2022
    Assignees: INFORWARD, INC, PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY, SHIBUYA CORPORATION
    Inventors: Akimichi Morita, Katsutoshi Sakano
  • Patent number: 11338151
    Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: May 24, 2022
    Assignee: KNOW Bio, LLC
    Inventors: Nathan Stasko, Nicholas William Medendorp, Jr., Gerald H. Negley, Katelyn P. Reighard
  • Patent number: 11331512
    Abstract: A system and method for determining or estimating the presence and effect of light-attenuating inhomogeneities in tissue when performing medical treatment or diagnostics using optical members in tissue. The system and method comprising inserting a plurality of optical members into the tissue, and then measuring by emitting light through a sub-set of optical members at a time, while measuring the light collected by another sub-set of optical members. Combining said measurement data with a model for light propagation in tissue, and setting up a system of equations. Solving the unknown attenuation values from said system of equations.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: May 17, 2022
    Assignee: SpectraCure AB
    Inventors: Johannes Swartling, Ida Arvidsson, Johan Axelsson
  • Patent number: 11324965
    Abstract: Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength ?1, to generate a second wavelength ?2 of radiation having a higher energy than the first wavelength ?1.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: May 10, 2022
    Assignees: IMMUNOLOIGHT, LLC., DUKE UNIVERSITY
    Inventors: Tuan Vo-Dinh, Jonathan P. Scaffidi, Venkata Gopal Reddy Chada, Benoit Lauly, Yan Zhang, Molly K. Gregas, Ian Nicholas Stanton, Joshua T. Stecher, Michael J. Therien, Frederic A. Bourke, Jr., Harold Walder, Zak Fathi, Jennifer A. Ayres, Zhenyuan Zhang, Joseph H. Simmons, Stephen John Norton
  • Patent number: 11324823
    Abstract: The present disclosure provides topical biophotonic materials and methods useful in phototherapy. In particular, the topical biophotonic materials of the present disclosure include a cohesive matrix, and at least one chromophore which can absorb and emit light from within the topical biophotonic material, wherein the topical biophotonic material is elastic. The topical bio-photonic materials and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: May 10, 2022
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Nikolaos Loupis, Remigio Piergallini, Eric Desrosiers
  • Patent number: 11305091
    Abstract: Disclosed are an apparatus and a system for managing circadian rhythm. The apparatus includes an illuminance measuring portion which measures a bio illuminance value of external light using a circadian lambda filter which passes the external light along according to a circadian rhythm sensitivity curve and a visual lambda filter which passes the external light along according to a visual sensitivity curve, a controller which outputs a control signal for reinforcing a user's circadian rhythm on the basis of the bio illuminance value, and a circadian rhythm reinforcing portion which emits light of a circadian wavelength band toward the user according to the control signal.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: April 19, 2022
    Assignee: KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
    Inventors: Hyun Sun Mo, Young Rag Do, Dae Jeong Kim, Dae Hwan Kim, Sung Yeon Jang, In Hwan Jung, Dong Myung Kim, Seong Jin Choi, Sanggyu Yim, Hyung Min Kim, Sun Woong Choi, Gu Min Jeong, Seung Min Lee
  • Patent number: 11285337
    Abstract: A light source and a method of generating a light using the light source is disclosed. The light source is configured to produce a plurality of distinct colors in generating the light, one of the distinct colors falling within a blue spectral light band. A light controller modulates the spectral light produced by the plurality of distinct colors. The modulation provides melanopsin contrast in order to increase melanopsin responsiveness of a subject exposed to the generated light and maintains the color temperature, color quality, and color constancy experienced by the subject in a lit viewing environment within an acceptable range.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: March 29, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Garen V. Vartanian, Kwoon Y. Wong, Pei-Cheng Ku, Scott A. Almburg
  • Patent number: 11273319
    Abstract: A method and apparatus irradiates a surface with at least one pulsed light beam emitted from an emission surface of an optical element. The at least one pulsed light beam comprises a plurality of pulses having a temporal pulsewidth in a range between about 0.1 millisecond and about 150 seconds. The at least one pulsed light beam has a beam cross-sectional area at the emission surface greater than about 2 cm2 and a time-averaged irradiance in a range between about 1 mW/cm2 and about 100W/cm2.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: March 15, 2022
    Assignee: Pthera LLC
    Inventors: Luis De Taboada, Jackson Streeter
  • Patent number: 11260241
    Abstract: A method and computer program product for suppressing the symptoms of multiple sclerosis (MS) by irradiating a subject exhibiting the symptoms with a pre-determined dose of UV-containing light from a light source and detecting a suppression of the clinical symptoms of MS. In particular, the detected suppression of the clinical symptoms is disassociated from the vitamin D production within the subject.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: March 1, 2022
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Hector F. Deluca, Bryan R. Becklund
  • Patent number: 11260242
    Abstract: Methods and systems for use in treating one or more patient's sensory impairment, e.g., associated with peripheral neuropathy. An exemplary system may be configured to generate treatment information for treating sensory impairment in at least one body portion using photonic energy from a therapeutic laser based on data indicative of damage.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: March 1, 2022
    Assignee: Biolyst, LLC.
    Inventors: Timothy Kelm, Philip S. Walter, Robert B. Weigel, Joshua Reed
  • Patent number: 11259391
    Abstract: Disclosed are a method and system for controlling a display condition which is pre-written into a passive light board by a mobile device. A display status is pre-written into a passive light board which is not powered by electricity before, and a control application program loaded into the mobile device is provided for a user to input a brightness parameter and a color temperature parameter. The light board which is not powered by electricity before can carry out the presetting of the display condition, and related manufacturers can set the light boards quickly and easily after the light boards exit the factory, and the light boards can display according to the conditions in compliance with the brightness parameter and the color temperature parameter after the light boards are powered on.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: February 22, 2022
    Inventors: Yung-Hong Wang, Brian A Cook, Chuan-Zhu Pan, Qin Zhou
  • Patent number: 11235149
    Abstract: Optogenetic signal processing is described for an auditory prosthesis with an intracochlear array of optical stimulation sources implanted in a patient having auditory neurons genetically modified with light sensitive ion channels. Stimulation timing signals are generated for the corresponding auditory neurons for each band pass signal based on characteristic temporal fine structure features of the band pass signals. The stimulation timing signals include: i. one or more channel opening signals adapted to open the ion channels of the corresponding auditory neurons, and ii. one or more channel closing signals adapted to close the ion channels of the corresponding ion channels. Optical stimulation signals are then produced for the optical stimulation sources based on the stimulation timing signals.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: February 1, 2022
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventors: Dirk Meister, Darshan Shah
  • Patent number: 11229808
    Abstract: Methods and apparatus provide therapeutic electromagnetic radiation (EMR) for inactivating infectious agents in, on or around a catheter residing in a patient's body cavity and/or for enhancing healthy cell growth. Transmitting non-ultraviolet therapeutic EMR substantially axially along an optical element in a lumen of the catheter body and/or the catheter body. Through delivery of the therapeutic EMR to particular infected areas and/or areas requiring tissue healing. The inactivation of the major sources of infection in, on, and around catheters and/or enhance healthy cell growth around catheters is accomplished by utilizing controlled relative intensity and/or treatment region specific dosing of the therapeutic EMR emitted radially from the optical element. Specific embodiments of urinary catheters and peritoneal dialysis catheters are also disclosed.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: January 25, 2022
    Inventors: Mitchell D. Barneck, Nathaniel L. R. Rhodes, James P. Allen, Curtis D. Long
  • Patent number: 11219553
    Abstract: A system for corneal treatment includes a light source that activates cross-linking in at least one selected region of a cornea treated with a cross-linking agent. The light source delivers photoactivating light to the at least one selected region of the cornea according to a set of parameters. The system includes a controller that receives input relating to the cross-linking agent and the set of parameters. The controller includes computer-readable storage media storing: (A) program instructions for determining cross-linking resulting from reactions involving ROS including at least peroxides, superoxides, and hydroxyl radicals, and (B) program instructions for determining cross-linking from reactions not involving oxygen. The controller executes the program instructions to output a calculated amount of cross-linking in the at least one selected region of the cornea. In response to the calculated amount of cross-linking, the light source adjusts at least one value in the set of parameters.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: January 11, 2022
    Assignee: Avedro, Inc.
    Inventors: Marc D. Friedman, Pavel Kamaev, Mikhail Smirnov
  • Patent number: 11219781
    Abstract: An illumination system (1) for photodynamic therapy is provided, the illumination system comprising an illumination source (2), which is configured to emit an electromagnetic radiation (3) to illuminate a target surface (4) during operation, and an electronic control unit (5), wherein the illumination source is configured such that the intensity of the electromagnetic radiation emitted by the illumination source can be varied, wherein the electronic control unit is operatively connected to the illumination source and configured to control operation of the illumination source according to an illumination protocol during an illumination session performed with the illumination system, and wherein the illumination protocol comprises instructions to operate the illumination source during the illumination session in a plurality of different modes, the modes comprising: a) a first mode, wherein, in the first mode, the electronic control unit controls operation of the illumination source such that the intensity of th
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: January 11, 2022
    Assignee: BIOFRONTERA PHARMA GMBH
    Inventors: Hermann Lübbert, Ben Novak, Markus Osterloh
  • Patent number: 11207544
    Abstract: The embodiments herein provide an LED based vaginal light therapy device for a plurality of bacterial and fungal infections. The device comprises an LED body, a cervix support, a single or a plurality of LEDs, a switch, a tether, microchip and a battery. One end of the device comprises a cervix support to place the device smoothly against the cervix. A plurality of LEDs is provided over the LED body. The LED body comprises one or more LEDs and each LED emits a light having a wavelength in a therapeutic zone of light. The light emitted are in a range of blue light and/or red light. The microchip is housed within the LED body. The microchip connects a battery to the single or plurality of LED's and is further connected to the switch.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: December 28, 2021
    Assignee: CERN Corporation
    Inventor: Gregg A. Klang
  • Patent number: 11202921
    Abstract: A phototherapy device, a kit containing such a phototherapy device, and a method for treating a patient with a phototherapy device, the phototherapy device containing a housing, an emission portion, and a light tube, the housing containing a light source that emits light at a wavelength of from about 400 nm to about 550 nm, and may contain a light shield proximal to the light source, the emission portion being distal form the housing and connected thereto via a light tube which contains an optical fibre, and a mesh that may enclose the optical fibre and may allow a limited amount of light to leak from the optical fibre to the outside environment.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: December 21, 2021
    Assignee: AVALON PHOTONICS (HK) LIMITED
    Inventors: Sai Keung Chow, Chun Lung Choi, Chi Yeung Mang, Chun Ho Wong, Johnson Yiu-Nam Lau
  • Patent number: 11197975
    Abstract: A light health care system including a physiological sensing device, a processor, and a light source device is provided. The physiological sensing device is adapted to acquire physiological data of a user. The processor is coupled to the physiological sensing device, and the processor acquires at least one light parameter corresponding to the physiological data according to the physiological data. The light source device is coupled to the processor, and the light source device outputs a light beam according to the at least one light parameter, wherein a green light beam or a blue light beam in the light beam accounts for more than 40% of the light beam. A light health care method is also provided.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: December 14, 2021
    Assignee: Industrial Technology Research Institute
    Inventors: Wei-Cheng Chao, Chi-Chin Yang, Li-Chi Su, Mu-Tao Chu
  • Patent number: 11167105
    Abstract: A method and apparatus for stimulating neural activity in the brain of a user of an apparatus with a display screen by causing at least one portion of the display screen to flicker in a controlled manner and utilizing the apparatus to measure an effect on a user exposed to the flicker for a time.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: November 9, 2021
    Assignee: SYMBOLICS INC.
    Inventor: Russell Noftsker
  • Patent number: 11154423
    Abstract: A system for corneal treatment includes a light source that activates cross-linking in at least one selected region of a cornea treated with a cross-linking agent. The light source delivers photoactivating light to the at least one selected region of the cornea according to a set of parameters. The system includes a controller that receives input relating to the cross-linking agent and the set of parameters. The controller includes computer-readable storage media storing: (A) program instructions for determining cross-linking resulting from reactions involving ROS including at least peroxides, superoxides, and hydroxyl radicals, and (B) program instructions for determining cross-linking from reactions not involving oxygen. The controller executes the program instructions to output a calculated amount of cross-linking in the at least one selected region of the cornea. In response to the calculated amount of cross-linking, the light source adjusts at least one value in the set of parameters.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: October 26, 2021
    Assignee: Avedro, Inc.
    Inventors: Marc D. Friedman, Pavel Kamaev, Mikhail Smirnov
  • Patent number: 11131454
    Abstract: A light emitting device array includes a substrate, a heat sink disposed on the substrate, at least two light emitting devices disposed on the heat sink and spaced apart from each other, a connector disposed on the light emitting device and configured to apply power, an insulating layer interposed between the heat sink and the connector, a fixing member configured to support a position of the light emitting device, on the light emitting device, and an adhesive layer provided on the fixing member to make contact with a skin.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: September 28, 2021
    Assignee: Gwangju Institute of Science and Technology
    Inventors: Jongho Lee, Juho Kim
  • Patent number: 11130000
    Abstract: A wearable for providing light therapy to a wearer includes at least one fabric panel having an inner surface that when the wearable is worn is configured to face a wearer's skin and an outer surface opposite the inner surface and at least one side-emitting optical fiber affixed to at least one of the inner surface and the outer surface. The side-emitting optical fiber is optically connectable with an optical fiber light source and configured to project light having a therapeutic wavelength toward a wearer of the wearable.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: September 28, 2021
    Assignee: BIOTHREAD LLC
    Inventors: Daniel Bish, Lawrence A. Blaustein, Jaleh Factor, Boris Kontorovich, Daniel Shuter, Jay Tapper
  • Patent number: 11118881
    Abstract: There is disclosed an IR illumination device and munitions comprising the same. There is provided an IR illumination munition device for selective activation where upon activation the device emits IR radiation in the range of wavelengths of from 750 nm to 900 nm, the device comprising: an electrical power source; an array of IR light emitting diodes to emit the IR radiation.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: September 14, 2021
    Assignee: BAE SYSTEMS plc
    Inventors: Mark Edward Roper, Martyn John Hucker
  • Patent number: 11110293
    Abstract: Phototherapy systems and methods of phototherapy are described. In an example, the phototherapy system includes a therapeutic light source configured to emit phototherapeutic light towards a subject; and a placebo light source configured to emit placebo light towards the subject. In an embodiment, the light, including the phototherapeutic light and the placebo light, emitted by the phototherapy system is configured to be visually perceived by the subject as continuous light. In an embodiment, the placebo light is a metameric match of the phototherapeutic light. In an embodiment, the method includes emitting the placebo light in a wavelength range and at an intensity configured to be visually perceived by the user as the phototherapeutic light, such as where the placebo light is a metameric match of the phototherapeutic light.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: September 7, 2021
    Assignee: L'OREAL
    Inventors: Geoffrey F. Deane, Lily Truong, Zane Bowman Allen Miller
  • Patent number: 11103725
    Abstract: A wireless optogenetic device in proximity to a neural cell of a subject includes a body configured to hold light transducing materials arranged to up-convert electromagnetic radiation in infrared or near-infrared spectrum into light in the visible spectrum to affect activity of the neural cell. The body allows electromagnetic radiation in infrared or near-infrared to reach the light transducing materials. A radiation system includes a radiation probe for irradiating a wireless optogenetic device with electromagnetic radiation in infrared or near-infrared spectrum from a radiation source. The system further includes a movement mechanism for moving the radiation probe, a detector for detecting a location of the wireless optogenetic device, and a controller for controlling the movement mechanism based on the detected location of the wireless optogenetic device such that the radiation probe is arranged to irradiate the wireless optogenetic device at the detected location with the electromagnetic radiation.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: August 31, 2021
    Assignee: City University of Hong Kong
    Inventors: Peng Shi, Ming Liu, Xudong Lin