Including Bio-absorbable Material Patents (Class 623/13.18)
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Patent number: 9486500Abstract: An osteoimplant is disclosed and includes a plurality of partially demineralized fibers. Each fiber has an elongated, thin body having a length of about 1 centimeter to about 3 centimeters. Further, the plurality of fibers engages to establish a matrix of material. The disclosure is further directed to a method of making the above-mentioned osteoimplant.Type: GrantFiled: January 28, 2010Date of Patent: November 8, 2016Assignee: Warsaw Orthopedic, Inc.Inventor: William F. McKay
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Patent number: 9284668Abstract: Devices and systems for use in soft tissue repair are provided, as are methods of manufacturing the same. In one exemplary embodiment, an implantable surgical construct includes an implant and a continuous braided closed filament loop that is attached to the implant. The continuous loop can be formed from a single strand of filament such that portions of the filament, sometimes referred to as tails, can be arranged with respect to each other to form a braided configuration. A related method of manufacture can involve passing portions of a single strand of filament around different sets of posts and selectively over and under each other to create the braided configuration. Other devices, systems, and methods of manufacturing are also provided, including some that involve using multiple strands of suture to form a continuous braided closed filament loop.Type: GrantFiled: March 14, 2013Date of Patent: March 15, 2016Assignee: MEDOS INTERNATIONAL SÁRLInventor: Stephen Johnson
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Patent number: 9271716Abstract: Suture constructs and methods are provided for securing soft tissue to bone. One exemplary embodiment of a construct includes a first limb, a second limb, a coaxial region, and a collapsible snare defined by the first and second limbs. The coaxial region can be formed by a portion of the second limb being disposed in a volume of the first limb, which allows for a low profile construct that is useful in various soft tissue repair procedures. The construct can be configured to be disposed in tissue to draw the tissue toward bone, and the coaxial region can be deconstructed so that the first and second limbs can be used to help secure the desired location of the tissue with respect to the bone. Various features of the construct and methods for using the same in a surgical procedure are also provided.Type: GrantFiled: December 27, 2012Date of Patent: March 1, 2016Assignee: MEDOS INTERNATIONAL SÀRLInventor: Mehmet Ziya Sengun
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Patent number: 9211362Abstract: A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.Type: GrantFiled: June 8, 2012Date of Patent: December 15, 2015Assignee: DePuy Mitek, LLCInventors: Julia Hwang, Joseph Hammer, Herb Schwartz, Prasanna Malaviya
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Patent number: 9192373Abstract: Suture constructs and methods are provided for securing soft tissue to bone. One exemplary embodiment of a construct includes a first limb, a second limb, a coaxial region, and a collapsible snare defined by the first and second limbs. The coaxial region can be formed by a portion of the second limb being disposed in a volume of the first limb, which allows for a low profile construct that is useful in various soft tissue repair procedures. The construct can be configured to be disposed in tissue to draw the tissue toward bone, and the coaxial region can be deconstructed so that the first and second limbs can be used to help secure the desired location of the tissue with respect to the bone. Various features of the construct and methods for using the same in a surgical procedure are also provided.Type: GrantFiled: December 31, 2013Date of Patent: November 24, 2015Assignee: MEDOS INTERNATIONAL SÀRLInventor: Mehmet Ziya Sengun
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Patent number: 9017404Abstract: Disclosed is a device and method for repairing a partially or totally ruptured tendon. The device comprises an implant placed inside or outside of the tendon on either side of the rupture in order to strengthen the ruptured area during repair. Once positioned inside the tendon, the tendon is held in place so it can heal either by sewing or stapling through the tendon and implant, or by any other suitable method that utilizes the implant to provide strength to the ruptured area. In this manner the tendon can heal with less chance of rupturing again prior to healing.Type: GrantFiled: October 9, 2012Date of Patent: April 28, 2015Inventors: Lloyd P. Champagne, Jozef Zoldos
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Patent number: 9011533Abstract: Anterior cruciate ligament reconstruction methods and devices are designed to achieve an anatomically accurate double bundle anterior cruciate ligament reconstruction by using a single femoral and tibial tunnel. The method and devices reconstruct the two bundles of the anterior cruciate ligament in a single femoral and tibial tunnel using a bone-patellar tendon-bone graft. The methods and devices enable an accurate anatomical reconstruction of the anteromedial and posterolateral bundles by creating a single femoral and tibial tunnel as opposed to creating two tunnels in the tibia and femur.Type: GrantFiled: October 13, 2009Date of Patent: April 21, 2015Assignee: The General Hospital CorporationInventors: Hemanth R. Gadikota, Thomas J. Gill, Guoan Li
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Patent number: 9005285Abstract: Medical delivery devices include a needle and a flexible compressible impermeable tube attached to the needle. The compressible tube has an open interior channel. The device is adapted to releasably hold a length of a medical implant in the open interior channel of the tube. The medical implant can be slidably inserted into the interior channel of the tube and is loosely held by the tube.Type: GrantFiled: May 11, 2011Date of Patent: April 14, 2015Assignee: MiMedx Group, Inc.Inventors: Mei Niu, Daniel Hernandez, Thomas J. Koob
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Publication number: 20150045887Abstract: This invention relates to a method for repair of a ligament and/or tendon in a patient comprising applying a patch to said ligament or tendon, wherein the patch is flexible, and bio-compatible and comprises a support layer and a matrix layer.Type: ApplicationFiled: March 22, 2013Publication date: February 12, 2015Applicant: TRB Chemedica International S.A.Inventor: Burkhard Mathies
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Patent number: 8945218Abstract: Degradable, polymeric fiber-based, three-dimensional braided scaffolds for use as graft materials in ligament and tendon repair, reconstruction and replacement are provided. Also provided are methods for preparing these scaffolds.Type: GrantFiled: May 25, 2007Date of Patent: February 3, 2015Assignee: Drexel UniversityInventors: Cato T. Laurencin, Frank K. Ko, James A. Cooper, Helen H. Lu, Mohammed A. Attawia
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Patent number: 8888849Abstract: A method of repairing soft tissue of a joint of a human extremity, such as a hand or foot. The method includes maintaining a metapodial bone intact; inserting a suture passing instrument into a space adjacent the metapodial and phalangeal bones; passing the suture through a volar ligament near a distal end of the metapodial bone and reattaching the volar ligament to the proximal phalanx. The method also includes making an incision on the dorsal aspect of the extremity to expose the dorsal aspect; inserting the distal portion of the suture passer instrument through the incision on the dorsal aspect of the extremity; inserting the distal portion of the suture passing instrument into a tendon sheath connected to a volar plate; and passing a portion of a suture through the volar plate.Type: GrantFiled: February 28, 2013Date of Patent: November 18, 2014Assignee: Smith & Nephew, Inc.Inventors: T Wade Fallin, M. Mary Sinnott
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Publication number: 20140277448Abstract: Surgical constructs and methods for tissue to bone repair employing a tissue construct reinforced with a reinforcement (reinforcing) material such as suture, tape, weave or mesh, among many others. The reinforced construct preferably includes a stitched reinforced region formed by employing a suture loop construct with a free floating needle that is attached to the suture loop, and also with a piece of material (a reinforcement or reinforcing material) attached to the suture loop. The reinforced construct may be attached to any fixation device and/or any bone tunnel.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: Arthrex, Inc.Inventors: James J. Guerra, Jacob A. Jolly, Dustin T. Libby, Thomas M. Deberardino
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Patent number: 8790682Abstract: A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.Type: GrantFiled: November 16, 2012Date of Patent: July 29, 2014Assignee: Bio2 Technologies, Inc.Inventors: James Jenq Liu, Adam Wallen, Juha-Pekka Nuutinen
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Publication number: 20140200667Abstract: Implants for osteo and osteochondral repair have been developed. These implants include a series of channels between the upper and lower surfaces of the implants, such that when implanted the lower surfaces are situated in an area rich in bone marrow and the channels provide a means for the bone marrow to migrate through the implant. Preferably the implants are made from resorbable polymer fibers, preferably arranged in braids that are knitted or woven together such that the braids are substantially parallel with each other. The implants may be rolled into a bundle of braids with the axis of the braids substantially parallel to the axis of the bundle, to provide channels along the axis of the bundle. A preferred embodiment includes P4HB fibers braided and knitted into a structure that is coated with a ceramic, preferably physiologic calcium phosphate.Type: ApplicationFiled: January 9, 2014Publication date: July 17, 2014Applicant: Tepha, Inc.Inventor: Andrew J. Carter
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Patent number: 8747468Abstract: Biocompatible coatings and spin finishes that can be applied to polyhydroxyalkanoate (PHA) polymers, and medical devices made from PHA polymers, have been developed. The coatings impart good lubricity to PHA polymers, particularly to fibers and braids made from these materials, making the coatings ideal for use on medical devices such as PHA braided sutures. The spin finishes can be applied to PHA fibers to facilitate their manufacture, and also for their conversion to other products, including medical textiles. The spin finishes serve to protect multifilament fiber bundles, and keep them intact following extrusion, and also to impart lubricity to the fiber bundles and monofilament fibers so that they are not damaged in subsequent processing steps particularly in textile processing. The coating reduces tissue drag of, for example, braided sutures.Type: GrantFiled: March 23, 2011Date of Patent: June 10, 2014Assignee: Tepha, Inc.Inventors: David P. Martin, Said Rizk, Jon I. Montcrieff, Dennis W. Connelly
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Patent number: 8703293Abstract: Provided herein re a composition and a coating or a device (e.g., absorbable stent) that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof.Type: GrantFiled: April 1, 2010Date of Patent: April 22, 2014Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Lothar W. Kleiner, Connie S. Kwok
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Publication number: 20130274879Abstract: Disclosed is a device and method for repairing a partially or totally ruptured tendon. The device comprises an implant placed inside or outside of the tendon on either side of the rupture in order to strengthen the ruptured area during repair. Once positioned inside the tendon, the tendon is held in place so it can heal either by sewing or stapling through the tendon and implant, or by any other suitable method that utilizes the implant to provide strength to the ruptured area. In this manner the tendon can heal with less chance of rupturing again prior to healing.Type: ApplicationFiled: October 9, 2012Publication date: October 17, 2013Inventors: Lloyd P. Champagne, Jozef Zoldos
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Publication number: 20130245762Abstract: A tendon repair implant for treatment of a partial thickness tear in the supraspinatus tendon of the shoulder is provided. The implant may incorporate features of rapid deployment and fixation by arthroscopic means that compliment current procedures; tensile properties that result in desired sharing of anatomical load between the implant and native tendon during rehabilitation; selected porosity and longitudinal pathways for tissue in-growth; sufficient cyclic straining of the implant in the longitudinal direction to promote remodeling of new tissue to tendon-like tissue; and, may include a bioresorbable construction to provide transfer of additional load to new tendon-like tissue and native tendon over time.Type: ApplicationFiled: May 8, 2013Publication date: September 19, 2013Inventors: Craig Van Kampen, Nathaniel Zenz-Olson, Thomas A. Westling, Charles L. Euteneuer
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Patent number: 8512405Abstract: The present invention provides a novel split barbed fixation device for tenodesis, soft tissue reattachment of tendons and ligaments to bones. The insertion device is adapted for an entirely arthroscopic approach while achieving fixation strength with ultimate pullout resistance comparable to interference screws. The device includes an integrated tendon grasper that provides for easy manipulation of the tendon arthroscopically while eliminating the need for external whip stitching of the tendon, thereby reducing preparation time. The device further includes elements that prevent the fixation implant from being destabilized or rotating during deployment and manipulation, including: a depth limiting sheath, a first implant retainer, a first implant retaining step, a tendon grasping needle tube, and an implant keyway for mating the implant to the tube.Type: GrantFiled: March 2, 2012Date of Patent: August 20, 2013Assignee: Cayenne Medical, Inc.Inventor: Kevin N. Baird
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Patent number: 8354119Abstract: A resorbable extracelluar matrix for reconstruction of cartilage tissue includes a mixture of collagen I and collagen II in a respective ratio of from about 1:19 to 19:1. The matrix can be utilized as a scaffold implant for vertebral or meniscal cartilage regeneration.Type: GrantFiled: November 19, 2002Date of Patent: January 15, 2013Assignee: ED. Geistlich Soehne AG Fuer Chemische IndustrieInventors: Peter Geistlich, Lothar Schloesser
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Patent number: 8337876Abstract: A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.Type: GrantFiled: July 8, 2010Date of Patent: December 25, 2012Assignee: Bio2 Technologies, Inc.Inventors: James Jenq Liu, Adam Wallen, Juha-Pekka Nuutinen
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Publication number: 20120253464Abstract: A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.Type: ApplicationFiled: June 8, 2012Publication date: October 4, 2012Applicant: DEPUY MITEK, INC.Inventors: Julia Hwang, Joseph Hammer, Herb Schwartz, Prasanna Malaviya
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Patent number: 8226715Abstract: A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.Type: GrantFiled: June 30, 2003Date of Patent: July 24, 2012Assignee: DePuy Mitek, Inc.Inventors: Julia Hwang, Joseph Hammer, Herb Schwartz, Prasanna Malaviya
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Patent number: 8127770Abstract: A method of treating a ligament or tendon according to the present invention can include inserting a tissue-generating implant into the ligament or tendon to thereby treat the defect. The tissue-generating implant has a plurality of microparticles. The microparticles subsequently form a biological scaffold which operates at least as partial connective tissue in the ligament or tendon giving structural support during regrowth.Type: GrantFiled: August 30, 2005Date of Patent: March 6, 2012Assignee: SpineOvations, Inc.Inventors: Neville Alleyne, Stuart Young
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Patent number: 8105391Abstract: Provided herein are a method, which comprises implanting in a patient an implantable device comprising a coating that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof.Type: GrantFiled: April 1, 2010Date of Patent: January 31, 2012Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Lothar W. Kleiner, Connie S. Kwok
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Patent number: 8070810Abstract: A method and a means for repair and reconstruction of ruptured ligaments and tendons by in vivo or ex vivo repair and reconstruction surgical procedures. The method comprises providing a biodegradable sleeve placed around the frayed edges of an injured ligament or tendon for protecting the ligament or tendon injury with a protective shield. A composition comprising a biodegradable tissue adhesive applied on top of, around and/or between the frayed edges of the injured ligament.Type: GrantFiled: January 12, 2007Date of Patent: December 6, 2011Assignee: Histogenics CorporationInventors: Laurence J. B. Tarrant, Akihiko Kusanagi, Robert Lane Smith
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Patent number: 7998204Abstract: A felt for repairing soft tissue defects comprising a membranous collagen substrate and a bioresorbable fiber felted onto the collagen substrate. Methods of preparing a felt and methods of repairing soft tissue damage with a felt are also provided.Type: GrantFiled: August 2, 2007Date of Patent: August 16, 2011Assignee: Biomet Sports Medicine, LLCInventors: Kevin T. Stone, Karen S. Troxel
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Patent number: 7776039Abstract: A device and method to provide a surgically inserted internal tether between the femur and tibia is provided which will prevent distraction of the healing anterior cruciate ligament in all degrees of flexion and extension, at all times. The anterior cruciate ligament tether preserves the four-bar cruciate linkage, critical for normal knee mechanics. In addition, placement of the tether provides bleeding into the knee in the region of the anterior cruciate ligament attachment sites and the consequent inflow of pluripotential cells and healing mediators.Type: GrantFiled: September 25, 2006Date of Patent: August 17, 2010Inventors: Joseph Bernstein, James L. Carey
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Publication number: 20100161054Abstract: The present disclosure provides an implantable medical device comprising a composite graft material including a first biologic component, such as an acellular tissue matrix, and a second non-biologic component.Type: ApplicationFiled: November 19, 2009Publication date: June 24, 2010Inventors: Jason Park, Aaron Barere, Christopher T. Wagner, Robert Kiefer, E. Skott Greenhalgh
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Patent number: 7713637Abstract: Provided herein are a coating or a device (e.g., absorbable stent) that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof.Type: GrantFiled: March 3, 2006Date of Patent: May 11, 2010Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Lothar W. Kleiner, Connie S. Kwok
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Publication number: 20090287308Abstract: The disclosure describes medical constructs with a plurality of collagen fibers twisted together and methods of twisting the collagen fibers to form the medical constructs.Type: ApplicationFiled: May 13, 2009Publication date: November 19, 2009Inventors: Tian Davis, Thomas J. Koob
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Patent number: 7585323Abstract: Musculoskeletal tissues produced in vitro are optimized in response to an externally applied mechanical load. The load applied may vary from tissue to tissue, depending upon the response desired, and may include intermittent axial, torsional, and bending loads to produce cortical structures. Compression alone is preferably applied to produce cancellous bone. A method according to the invention for culturing bone in vitro comprises: providing a culture vessel providing a scaffold material, supporting the scaffold material within the tissue culture vessel so as to be exposed to a tissue culture medium, and exerting a force on the scaffold material during growth of a bone construct (a cultured bone growth) around the scaffold material.Type: GrantFiled: May 7, 2001Date of Patent: September 8, 2009Assignee: Medlden, LLCInventors: Michael A. Masini, Martin S. Bancroft
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Publication number: 20090030454Abstract: A resorbable implantable device, such as a suture or prosthesis, comprising one or more silk elements made at least partially (poly)alanine Wild silk proteins of a saturnid moth or analogues thereof.Type: ApplicationFiled: April 5, 2006Publication date: January 29, 2009Inventors: David Philip Knight, Christine Ortlepp, Nicholas Skaer
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Publication number: 20080161806Abstract: A radially expandable sheath is provided having a substantially closed distal end with at least two sidewalls extending proximally therefrom and defining a central lumen. Each sidewall can have a substantially concave outer surface adapted to seat a graft member, and each side wall is at least partially separated by a longitudinally oriented slot that extends from a proximal end along a substantial length of each sidewall. The slot preferably terminates at a position just proximal to the distal end. The device can also include a sheath expander that is adapted to be disposed in the central lumen of the radially expandable sheath and that is configured to flex the sidewalls to radially expand the sheath so as to fix a graft member within a bone tunnel.Type: ApplicationFiled: February 5, 2008Publication date: July 3, 2008Applicant: DEPUY MITEK, INC.Inventors: Lisa M. Donnelly, Nathan S. Cauldwell
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Publication number: 20080133007Abstract: A radially expandable sheath is provided having a substantially closed distal end with at least two sidewalls extending proximally therefrom and defining a central lumen. Each sidewall can have a substantially concave outer surface adapted to seat a graft member, and each side wall is at least partially separated by a longitudinally oriented slot that extends from a proximal end along a substantial length of each sidewall. The slot preferably terminates at a position just proximal to the distal end. The device can also include a sheath expander that is adapted to be disposed in the central lumen of the radially expandable sheath and that is configured to flex the sidewalls to radially expand the sheath so as to fix a graft member within a bone tunnel.Type: ApplicationFiled: November 6, 2007Publication date: June 5, 2008Applicant: DEPUY MITEK, INC.Inventors: Lisa M. Donnelly, Nathan S. Cauldwell
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Patent number: 7309355Abstract: A radially expandable sheath is provided having a substantially closed distal end with at least two sidewalls extending proximally therefrom and defining a central lumen. Each sidewall can have a substantially concave outer surface adapted to seat a graft member, and each side wall is at least partially separated by a longitudinally oriented slot that extends from a proximal end along a substantial length of each sidewall. The slot preferably terminates at a position just proximal to the distal end. The device can also include a sheath expander that is adapted to be disposed in the central lumen of the radially expandable sheath and that is configured to flex the sidewalls to radially expand the sheath so as to fix a graft member within a bone tunnel.Type: GrantFiled: June 27, 2003Date of Patent: December 18, 2007Assignee: DePuy Mitek, Inc.Inventors: Lisa M. Donnelly, Nathan S. Cauldwell
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Publication number: 20070198087Abstract: Interposition and augmentation devices for tendon and ligament repair, including rotator cuff repair, have been developed as well as methods for their delivery using arthroscopic methods. The devices are preferably derived from biocompatible polyhydroxyalkanoates, and preferably from copolymers or homopolymers of 4-hydroxybutyrate. The devices may be delivered arthroscipiclly, and offer additional benefits such as support for the surgical repair, high initial strength, prolonged strength retention in vivo, flexibility, anti-adhesion properties, improved biocompatibility, an ability to remodel in vivo to healthy tissue, minimal risk for disease transmission or to potentiate infection, options for fixation including sufficiently high strength to prevent suture pull out or other detachment of the implanted device, eventual absorption eliminating future risk of foreign body reactions or interference with subsequent procedures, competitive cost, and long-term mechanical stability.Type: ApplicationFiled: February 5, 2007Publication date: August 23, 2007Inventors: Struan Coleman, David P. Martin, Said Rizk, Ajay Ahuja, Simon F. Williams
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Patent number: 7001429Abstract: A method of securing soft tissue to a prosthesis that has a retaining member secured thereto is disclosed. The method includes looping a first end portion of a first band around the retaining member such that both the first end portion of the first band and a second end portion of the first band extend outwardly from the retaining member. The method further includes looping a first end portion of a second band around the retaining member such that both the first end portion of the second band and a second end portion of the second band extend outwardly from the retaining member. Moreover, the method includes securing the soft tissue to (i) the first end portion and the second end portion of the first band, and (ii) the first end portion and the second end portion of the second band.Type: GrantFiled: June 17, 2003Date of Patent: February 21, 2006Assignee: DePuy Orthopaedics, Inc.Inventor: Joe W. Ferguson
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Patent number: 6875216Abstract: A bioabsorbable interference screw having a tapered profile which extends along substantially the entire length of the screw. The tapered profile makes the screw easy to insert while providing superior fixation resulting from a progressively increasing diameter. Upon insertion, the screw engages cortical bone at the back end of the bone tunnel and fills all but 5-10 mm. of the tunnel, thereby providing increased fixation strength while also promoting fast healing. The screw includes a head provided with a specially designed drive socket with radially extending slots at its outer end for receiving corresponding protrusions on the shaft of screwdriver. The drive socket optimizes the torque capacity of the screw. To maintain wall thickness, the socket has a taper corresponding to the tapered outer profile of the screw. The taper of the socket also permits easy insertion of the tip and shaft of the driver into the screw.Type: GrantFiled: August 6, 2003Date of Patent: April 5, 2005Assignee: Arthrex, Inc.Inventor: Eugene M. Wolf
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Patent number: 6869701Abstract: A protective coating for a substrate is disclosed having an outer component or module formed of a swellable material and an inner module formed of a plurality of layer or bilayers formed of ceramic material. The coating comprising a plurality of modules comprising a first module comprising a number (m) of bilayers comprising zirconia and alumina wherein (m) is a number greater than 1. The coating further comprises a second module disposed on the first module comprising a number (n) of bilayers comprising zirconia and titania wherein (n) is a number greater than 1. The coating further comprises a third module disposed on the second module comprising a third-module compound capable of forming a hydrate or hydroxide compound upon contact with an oxygen containing environment.Type: GrantFiled: August 16, 1999Date of Patent: March 22, 2005Inventors: Carolyn R. Aita, Vladislav V. Yakovlev, Mary M. Cayton, Mahmood Mirhoseini, Michael Aita
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Publication number: 20040267361Abstract: A radially expandable sheath is provided having a substantially closed distal end with at least two sidewalls extending proximally therefrom and defining a central lumen. Each sidewall can have a substantially concave outer surface adapted to seat a graft member, and each side wall is at least partially separated by a longitudinally oriented slot that extends from a proximal end along a substantial length of each sidewall. The slot preferably terminates at a position just proximal to the distal end. The device can also include a sheath expander that is adapted to be disposed in the central lumen of the radially expandable sheath and that is configured to flex the sidewalls to radially expand the sheath so as to fix a graft member within a bone tunnel.Type: ApplicationFiled: June 27, 2003Publication date: December 30, 2004Inventors: Lisa M. Donnelly, Nathan S. Cauldwell
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Publication number: 20040267362Abstract: A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.Type: ApplicationFiled: June 30, 2003Publication date: December 30, 2004Inventors: Julia Hwang, Joseph Hammer, Herb Schwartz, Prasanna Malaviya
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Patent number: 6773459Abstract: A medical, bioresorbable implant, particularly for cruciate ligament augmentation, is constructed as a composite structure in textile construction from at least two biocompatible polymer materials, which differ in their chemical composition and/or polymer structure and which are degradable, the implant having a predetermined initial tensile stiffness and a different degradation behaviour of the polymers and/or the textile construction is selected in such a way that the tensile stiffness decreases during degradation.Type: GrantFiled: September 12, 2001Date of Patent: August 10, 2004Assignees: Deutsche Institute fuer Textil-und Faserforschung Stuttgart Stiftung des oeffentlichen RechtsInventors: Martin Dauner, Helmut Hierlemann, Heinrich Planck, Lutz Claes, Lutz Duerselen, Anita Ignatius
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Publication number: 20040093081Abstract: A characteristic features of the invention is that a spacer member (1) is intended to be placed between the ends of the bones which are to be connected, one end of the spacer member being designed to form a joint surface against one of said bone ends (6, 7). A joint-stabilizing connection (2, 3) is arranged to connect said ones. The spacer member (1) is made of at least one tissue-compaiible material.Type: ApplicationFiled: December 23, 2003Publication date: May 13, 2004Inventors: Anders Nilsson, Bengt Edberg
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Publication number: 20040044408Abstract: The invention is directed to the culture of cells, and particularly chondrocytes for purpose of tissue replacement. The cells are cultured on polymer constructs. Integren expression is used as a measure of chondrocyte viability. Chondrocytes are obtained from the knee, nose and ankle cartilage. Mechanical strain is used to propagate chondrocytes, chitosan and arabinogalactan-chitosan are used as scaffolds. Progenitor, pluripotential, stem and mesenchymal cells are operative in this invention.Type: ApplicationFiled: September 3, 2003Publication date: March 4, 2004Inventors: David S. Hungerford, Carmelita G. Frondoza, Alan H. Shikani, Abraham J. Domb
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Publication number: 20040034418Abstract: An implant that contains a membrane and a polymeric matrix covered by the membrane. Both the matrix and the membrane are biocompatible and bioresorbable. Also disclosed is a method of preparing such an implant.Type: ApplicationFiled: July 23, 2002Publication date: February 19, 2004Inventors: Shu-Tung Li, Tom Smestad, Julie Pon, Robert McNeill
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Patent number: 6629977Abstract: A bioabsorbable interference screw having a tapered profile which extends along substantially the entire length of the screw. The tapered profile makes the screw easy to insert while providing superior fixation resulting from a progressively increasing diameter. Upon insertion, the screw engages cortical bone at the back end of the bone tunnel and fills all but 5-10 mm. of the tunnel, thereby providing increased fixation strength while also promoting fast healing. The screw includes a head provided with a specially designed drive socket with radially extending slots at its outer end for receiving corresponding protrusions on the shaft of screwdriver. The drive socket optimizes the torque capacity of the screw. To maintain wall thickness, the socket has a taper corresponding to the tapered outer profile of the screw. The taper of the socket also permits easy insertion of the tip and shaft of the driver into the screw.Type: GrantFiled: November 15, 2000Date of Patent: October 7, 2003Assignee: Arthrex, Inc.Inventor: Eugene M. Wolf
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Patent number: 6626942Abstract: Biodegradable porous implants are provided which are biocompatible with humans and animals, and which comprise bundles of flexible threads, each of the bundles including a plurality of flexible threads, each of the plurality of flexible threads comprising from 50 to 500 filaments having a combined density of from 5 to 120 tex, each of the bundles having a twist of up to 120 revolutions per meter, and including weft threads holding together the plurality of bundles, the weft threads having a distribution density of up to about 100 threads per cm calculated in the longitudinal direction of the flexible threads.Type: GrantFiled: June 13, 2001Date of Patent: September 30, 2003Assignee: Artimplant ABInventor: Bengt Edberg
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Patent number: 6592622Abstract: An apparatus for securing soft tissue to a prosthesis includes a retaining member secured to the prosthesis. The apparatus also includes a first band constructed of a resorbable material. The first band has a first end portion, a middle portion, and a second end portion. The apparatus also includes a second band constructed of a biologically inert material. The second band has a first end portion, a middle portion, and a second end portion. The middle portion of the first band is positioned around a retaining portion of the retaining member such that both the first end portion and the second end portion of the first band extend outwardly from the retaining member. The middle portion of the second band is positioned around the retaining portion of the retaining member such that both the first end portion and the second end portion of the second band extend outwardly from the retaining member.Type: GrantFiled: October 24, 2000Date of Patent: July 15, 2003Assignee: DePuy Orthopaedics, Inc.Inventor: Joe W. Ferguson
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Publication number: 20030097180Abstract: The present invention provides a joint prosthesis system for the joining of two bones. The bioabsorbable joint prosthesis system includes at least one bioabsorbable spacer and at least one connector adapted to be fixedly attached to the two bones, at least a portion of the connector being in contact with the spacer to prevent lateral movement of the spacer. The present invention also includes embodiments drawn to methods of using the joint prosthesis system. In an embodiment of the present invention, the method includes interposing at least one bioabsorbable spacer between the surface of the bones to be joined and connecting the bones with at least one connector such that at least a part of the connector contacts the bioabsorbable spacer.Type: ApplicationFiled: November 20, 2001Publication date: May 22, 2003Inventors: Pertti Tormala, Mauri Lehtimaki, Matti Lehto, Minna Kellomaki, Pirjo Honkanen