Annular Member For Supporting Artificial Heart Valve Patents (Class 623/2.38)
  • Patent number: 10478289
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: November 19, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider
  • Patent number: 10426604
    Abstract: A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: October 1, 2019
    Assignee: St. Jude Medical, LLC
    Inventor: Peter N. Braido
  • Patent number: 10413401
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: September 17, 2019
    Assignee: MEDTRONIC CV LUXEMBOURG S.A.R.L.
    Inventors: Carol Eberhardt, Gopikrishnan Soundararajan, Kenny Dang, Hussain Rangwala
  • Patent number: 10376680
    Abstract: Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter and/or a removable and/or replaceable shunt portion. Devices may include absorbable materials, the absorption of which directly or indirectly causes alterations of the fluid flow capacities the devices.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: August 13, 2019
    Assignee: Corvia Medical, Inc.
    Inventors: Edward I. McNamara, Michael W. Sutherland, Matthew J. Finch, Stephen J. Forcucci
  • Patent number: 10314693
    Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. A cuff may be coupled to the stent so that a flat, bottom edge of the cuff lies adjacent the proximal end of the stent. A pattern of stitches may be circumferentially disposed around the flat bottom edge of the cuff, the pattern of stitches alternating between stitches sewn to the cuff only and stitches sewn to both the cuff and the stent.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: June 11, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Andrea L. McCarthy, Kent J. Smith
  • Patent number: 10226336
    Abstract: A stented prosthetic heart valve including a stent assembly, a leaflet assembly, and mounting members. The stent assembly includes a stent post frame, a stent post frame covering, and a base frame. The stent post frame includes a continuous rail forming a closed-curved shape defining a longitudinal axis, and a plurality of circumferentially-spaced posts projecting from cusp segments in a direction of the longitudinal axis. The cloth covering encompasses the rail. The base frame supports the cusp segments. The valve leaflet assembly is attached to the stent assembly, and includes a leaflet clamped between one of the cusp segments and the base frame. The mounting members each directly pass through the stent post frame cloth covering, the first leaflet and the base frame. The rail can have a constant cross-sectional shape with a major axis dimension that is greater than a minor axis dimension.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: March 12, 2019
    Assignee: Medtronic, Inc.
    Inventors: Jason Beith, Elliot Howard
  • Patent number: 10130462
    Abstract: An intra-annular mounting frame for an aortic valve having native aortic cusps is provided which includes a frame body with native leaflet reorienting curvatures and interconnecting points; the curvatures shaped to be received inside the valve below the native aortic cusps and to reorient the native aortic cusps within the aortic valve, where each of the curvatures extends concavely upward from a reference latitudinal plane tangential to each curvature's base.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: November 20, 2018
    Assignee: BioStable Science & Engineering, Inc.
    Inventor: J. Scott Rankin
  • Patent number: 10086184
    Abstract: The various implementations described herein include methods used to manufacture a percutaneous port for promoting tissue in-growth around the percutaneous port. In one aspect, the method includes providing a tubular structure having an outer surface and providing a coil having an outer surface and comprised of a plurality of loops. The method further includes joining at least a portion of the outer surface of the coil to the outer surface of the tubular structure.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: October 2, 2018
    Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Guangqiang Jiang, Tom He
  • Patent number: 10080653
    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: September 25, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian S. Conklin, Da-Yu Chang
  • Patent number: 10052198
    Abstract: A coiled anchor for docking a mitral valve prosthesis at a native mitral valve of a heart has a first end, a second end, and a central axis extending between the first and second ends, and defines an inner space coaxial with the central axis. The coiled anchor includes a coiled core including a bio-compatible metal or metal alloy and having a plurality of turns extending around the central axis in a first position, and a cover layer around the core, the cover layer including a bio-compatible material that is less rigid than the metal or metal alloy of the coiled core.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: August 21, 2018
    Assignee: Mitral Valve Technologies Sarl
    Inventors: Mark Chau, Alexander J. Siegel, Paul A. Spence, Landon H. Tompkins
  • Patent number: 10052202
    Abstract: A heart valve assembly has a frame comprising an anchoring section, a generally cylindrical leaflet support section, and a neck section that transitions between the anchoring section and the valve support section. The anchoring section has a ball-shaped configuration defined by a plurality of wires that extend from the leaflet support section, with each wire extending radially outwardly to a vertex area where the diameter of the anchoring section is at its greatest, and then extending radially inwardly to a hub. A plurality of leaflets are stitched to the leaflet support section. The heart valve assembly is delivered to the location of a native pulmonary trunk, the vertex area of the anchoring section is deployed into the native pulmonary arteries such that the vertex area is retained in the pulmonary arteries, and then the leaflet support section is deployed in the pulmonary trunk.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: August 21, 2018
    Assignee: Venus Medtech (Hangzhou) Inc
    Inventors: Min Frank Zeng, Pham Lo
  • Patent number: 9980814
    Abstract: The kit (10) of the invention includes a valve bearing (16) that can be radially deformed. The bearing (16) includes an outer peripheral wall (22) defining a central passage (40) having an axis (X-X?). The bearing (16) further includes an inner peripheral wall (24) defining an inner lumen (44) having a radial dimension lower than that of the central passage (40). The kit (10) includes a prosthetic valve (18) to be placed on the inner peripheral wall (24). The inner peripheral wall (24) extends in the central passage axially relative to the outer wall (22). The valve bearing (16) includes a means (26) for maintaining the inner peripheral wall (24) radially remote from the outer peripheral wall (22). The inner peripheral wall (24) and the maintaining means (26) define an inner blood circulation region (56) containing the lumen (44) which is tightly isolated from an outer region (58).
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: May 29, 2018
    Assignee: CORMOVE
    Inventor: Mikolaj Styrc
  • Patent number: 9827095
    Abstract: A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: November 28, 2017
    Assignee: HLT, Inc.
    Inventors: Gary A. Thill, Robert Foster Wilson, John P. Gainor, Christopher M. Banick
  • Patent number: 9820851
    Abstract: A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: November 21, 2017
    Assignee: St. Jude Medical, LLC
    Inventor: Peter N. Braido
  • Patent number: 9775704
    Abstract: The present invention provides valve prostheses adapted to be initially crimped in a narrow configuration suitable for catheterization through body ducts to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: October 3, 2017
    Assignee: Medtronic3F Therapeutics, Inc.
    Inventors: Bjarne Bergheim, Keith E. Myers, Jeffrey P. DuMontelle, Christine Nguyen
  • Patent number: 9649192
    Abstract: A method for heart valve surgery may include providing a cardiac valve ring and suture loops connected to the cardiac valve ring, accessing a valve annulus of the heart of the patient, stapling at least one of the sutures loop to the valve annulus, and parachuting the cardiac valve ring down the suture to the valve annulus after the stapling. The cardiac valve ring may be an annuloplasty ring, a replacement heart valve, or other medical device.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: May 16, 2017
    Assignee: Dextera Surgical Inc.
    Inventor: Bernard A. Hausen
  • Patent number: 9622863
    Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: April 18, 2017
    Assignee: Edwards Lifesciences Corporation
    Inventors: Emil Karapetian, Charles Stanislaus, Gregory Bak-Boychuk, Christopher Olson, Cristobal Hernandez, William Brunnett, Netanel Benichou, Lauren Freschauf, Alex Siegel
  • Patent number: 9605534
    Abstract: A system, method and computer-readable medium for monitoring a fluid injection at a downhole location in a wellbore is disclosed. A member is provided in the wellbore. The member includes a passage for flow of fluid and a fiber optic cable including a plurality of temperature sensitive sensors wrapped around the member. A selected temperature signal is imparted into the fluid flowing in the member. A temperature of the fluid exiting the member at the downhole location is measured using the plurality of temperature sensors. The measured temperature and the imparted temperature signal are compared to determine a flow parameter of the injected fluid.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: March 28, 2017
    Assignee: BAKER HUGHES INCORPORATED
    Inventors: Jeff Chen, Luis E. Mendez, Chee M. Chok, Xudong Yang
  • Patent number: 9585749
    Abstract: A replacement heart valve assembly. An expandable anchor is disclosed that has a skirt region, a lip region, and a plurality of posts attached to the skirt region. A replacement heart valve is attached to the posts. The lip region has interlocking elements that are secured to the posts where the interlocking elements have eyelets. Tabs extend into the eyelets to mate with holes in the posts.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: March 7, 2017
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 9539088
    Abstract: A fixation band for affixing a prosthetic heart valve to tissue having proximal and distal annular portions positionable relative to one another, the proximal and distal annular portions each having a proximal and distal sides, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and a prosthetic heart valve being attachable to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device operative between the proximal and distal annular portions for selectively positioning the proximal and distal annular members toward one another for compressing the staples therebetween and deploying the staples into tissue so as to affix the prosthetic heart valve to tissue.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: January 10, 2017
    Assignee: Medtronic, Inc.
    Inventors: Steven B. Woolfson, Richard B. Streeter, Daniel C. Taylor, John R. Liddicoat
  • Patent number: 9526614
    Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a second loop-shaped support, which is configured to abut a second side of the heart valve opposite to said first side, whereby a portion of the valve tissue is trapped between the first and second supports. An outer boundary of the second support is greater than an outer boundary of the first support.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: December 27, 2016
    Assignee: Medtentia International Ltd. Oy
    Inventor: Olli Keränen
  • Patent number: 9474601
    Abstract: A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: October 25, 2016
    Assignee: Medtronic, Inc.
    Inventors: Michael J. Drews, Donnell W. Gurskis, Stephen R. Bacich
  • Patent number: 9393113
    Abstract: A method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a catheter to a vicinity of the heart valve; deploying the anchor from the catheter; expanding the anchor to contact tissue at an anchor site; and retrieving the anchor into the catheter. The invention also includes an apparatus for endovascularly replacing a heart valve, including: a catheter; a replacement valve configured to be disposed within the catheter for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the catheter for delivery to a vicinity of the heart valve, to be deployed from the catheter, to be expanded to contact tissue at an anchor site and to be retrieved back into the catheter after having been expanded.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: July 19, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 9289289
    Abstract: A device for anchoring a prosthetic heart valve on biological tissue, includes first and second anchoring assemblies, mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: March 22, 2016
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Giovanni Rolando, Mauro Ercolani, Paolo Gaschino, Andrea Marchisio
  • Patent number: 9277991
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: March 8, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 9211361
    Abstract: This invention relates to processes of preparing heterogeneous graft material from animal tissue. Specifically, the invention relates to the preparation of animal tissue, in which the tissue is cleaned and chemically cross-linked using both vaporized and liquid cross-linking agents, resulting in improved physical properties such as thin tissue and lowered antigenicity, thereby increasing the ease of delivering the tissue during surgery and decreasing the risk of post-surgical complication, respectively.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: December 15, 2015
    Inventor: Kemal Schankereli
  • Patent number: 9161836
    Abstract: A device for anchoring on biological tissue a prosthetic heart valve, includes first and second anchoring assemblies mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: October 20, 2015
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Giovanni Rolando, Mauro Ercolani, Paolo Gaschino, Andrea Marchisio
  • Patent number: 9066801
    Abstract: Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: June 30, 2015
    Assignee: Medtronic, Inc.
    Inventors: Igor Kovalsky, Ilia Hariton, Yossi Tuval, Nadav Yellin
  • Publication number: 20150127093
    Abstract: Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native chordae tendineae and/or leaflets of a valve. The support member can comprise a flexible, distensible material to reduce abrasion and other mechanical damage to surrounding structures. A locking member may be used to couple both ends of the support member, forming a support ring. The support member may have two magnetic end portions which can be magnetically coupled to form a support ring. An expandable prosthetic heart valve can be delivered into the native heart valve and expanded within the support band, thereby causing one or more of the native chordae tendineae and/or leaflets of the native heart valve to be frictionally secured between the support ring and the expanded prosthetic heart valve.
    Type: Application
    Filed: September 9, 2014
    Publication date: May 7, 2015
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ronald J. Hosmer, Erin M. Spinner
  • Publication number: 20150127100
    Abstract: A prosthetic heart valve may include a stent body with a plurality of cells arranged in circumferential rows and a cuff attached to the stent. A leaflet attachment panel may be attached to and span a portion of one of the cells. A prosthetic valve element, such as a leaflet having a belly, may be mounted to the leaflet attachment panel. The leaflet attachment panel may not be integral with the stent body. A reduced overlap area may be defined between a proximal end of the stent body and a proximalmost point of attachment of the leaflet belly to the cuff. The reduced overlap area may have a size dependent upon the circumferential row of cells the leaflet attachment panel is attached to and a position of the portion of the leaflet attachment panel to which the leaflet is mounted. Alternately, the leaflet may be attached directly to the stent.
    Type: Application
    Filed: November 5, 2014
    Publication date: May 7, 2015
    Inventors: Peter N. Braido, Kent J. Smith
  • Patent number: 9023102
    Abstract: A medical device used in cardiac surgery for replacement of diseased heart valves in humans. A heart valve prosthesis comprising a housing 1 having a projection 3 along its whole perimeter 2, an occluder 4 which restricts the blood backflow (I), and a cuff 5 made of fabric and having a mounting surface 6which comes into contact with cardiac tissues (II), and an outer surface 7 which comes into contact with the blood flow. Inside the cuff 5 are located a stent 8 forming an opening 9 for installation of the prosthesis housing 1, a supporting element 10 and a retaining element 11 which fix the projection 3 of the housing 1 within the stent 8 of the cuff 5 forming a quick-dismountable junction of the housing 1 with the cuff 5.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: May 5, 2015
    Assignee: MedEng
    Inventors: Sergey Vasilyevich Evdokimov, Alexandr Sergeyevich Evdokimov, Eduard Yurievich Goncharov, Alexandr Nikolayevich Filippov
  • Publication number: 20150119982
    Abstract: Mitral valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion. The inflow portion is formed from a plurality of struts that outwardly extend from the first end of the valve-retaining tubular portion with adjacent struts of the plurality of struts being joined, wherein each strut of the plurality of struts has a substantially s-shaped profile and at least one twisted area.
    Type: Application
    Filed: October 21, 2014
    Publication date: April 30, 2015
    Inventors: Jason Quill, Igor Kovalsky
  • Publication number: 20150112427
    Abstract: Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy.
    Type: Application
    Filed: May 2, 2014
    Publication date: April 23, 2015
    Applicant: Caisson Interventional LLC
    Inventors: Cyril J. Schweich, JR., Todd J. Mortier
  • Publication number: 20150112433
    Abstract: Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy.
    Type: Application
    Filed: May 2, 2014
    Publication date: April 23, 2015
    Applicant: Caisson Interventional LLC
    Inventors: Cyril J. Schweich, JR., Todd J. Mortier
  • Publication number: 20150105857
    Abstract: A device useful for implantation at a native heart valve can include an anchor element having a tubular configuration defining a longitudinal direction and a circumference, a heart valve prosthesis disposed within the anchor element, and a plurality of elongate members positioned at equidistant angular intervals about the circumference of the anchor element. The device can be configured to be transitioned from a radially collapsed delivery configuration to a radially expanded implantation configuration, and the plurality of elongate members can have a length extending in the longitudinal direction of the tubular member in the expanded implantation configuration.
    Type: Application
    Filed: December 19, 2014
    Publication date: April 16, 2015
    Applicants: MEDTRONIC VASCULAR GALWAY LIMITED, JENAVALVE TECHNOLOGY GMBH
    Inventors: Philipp BONHOEFFER, Younes BOUDJEMLINE
  • Patent number: 8998982
    Abstract: The invention provides a device for fine adjustment of a prosthetic valve device and a method of adjusting the position of a prosthetic valve after implantation. The adjustment mechanism includes complementary structures on a valve member and device frame that cooperate to provide relative axial and/or angular motion between the valve member and device frame (and thus the native vessel). The adjustment mechanism of the invention may also include a means for selectively maintaining the relative position of the valve member and device frame. The device and method are particularly applicable for use with a modular prosthetic valve device that is assembled in the body lumen.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: April 7, 2015
    Assignee: Valve Medical Ltd.
    Inventors: Yoram Richter, Jacob Richter, Ety Weisz
  • Publication number: 20150094804
    Abstract: A device useful for implantation at a native heart valve can include an anchor element having a tubular configuration defining a longitudinal direction and a circumference, a heart valve prosthesis disposed within the anchor element, and a plurality of elongate members positioned at equidistant angular intervals about the circumference of the anchor element. The device can be configured to be transitioned from a radially collapsed delivery configuration to a radially expanded implantation configuration, and the plurality of elongate members can have a length extending in the longitudinal direction of the tubular member in the expanded implantation configuration.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Applicants: MEDTRONIC VASCULAR GALWAY LIMITED, JENAVALVE TECHNOLOGY GMBH
    Inventors: Philipp BONHOEFFER, Younes BOUDJEMLINE
  • Publication number: 20150094802
    Abstract: The present invention is primarily directed a prosthetic cardiac valve support device adapted for endovascular delivery to a cardiac valve, comprising a single ring-shaped support element having an inner diameter and an outer diameter, wherein said support element has an outer perimeter that is entirely rigid, wherein said support element is fitted with one or more intra-ventricular and/or intra-atrial stabilizing elements, and wherein said support element has a collapsed delivery configuration and a deployed configuration.
    Type: Application
    Filed: August 28, 2014
    Publication date: April 2, 2015
    Inventors: Maurice BUCHBINDER, Shay DUBI, Amit TUBISHEVITZ, Avi EFTEL
  • Patent number: 8992607
    Abstract: A prosthetic anatomical device, such as, for example an annuloplasty prosthesis, is disclosed in which the prosthesis comprises a generally annular core and a cover surrounding the core, with at least a portion of the cover forming a cuff. In some embodiments, the cover may be particularly configured about the core to form the cuff. Various methods and structures for mitigating or retarding movement between the annular core and the fabric cover are also disclosed.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: March 31, 2015
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Chad Joshua Green, Grant Tsuchiya, Mindy Lor, Bruce Roman Musolf, Zhengrong Zhou, Gary Fischbach
  • Patent number: 8992608
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: March 31, 2015
    Assignee: Sadra Medical, Inc.
    Inventors: Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Amr Salahieh, Dwight P. Morejohn, Kenneth J. Michlitsch
  • Patent number: 8986375
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 24, 2015
    Assignee: Medtronic, Inc.
    Inventors: Kshitija Garde, Philip Haarstad, Igor Kovalsky, Stephen Nash, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Jeffrey Sandstrom, Padraig Savage, William Steinberg
  • Publication number: 20150073548
    Abstract: An expandable member that is configured to engage an interior region of a prosthetic valve and capable of transitioning from a pre-deployment configuration at a pre-deployment temperature, where the expandable member is capable of being positioned in the valve at an interior valve region when the valve is disposed in a cardiovascular structure, to a post-deployment configuration when the expandable member is subjected to cardiovascular tissue temperature, where an outer surface region of the valve proximate the interior valve region is placed in intimate contact with host cardiovascular tissue of the cardiovascular structure at a first position and seals perivalvular leaks present at the first cardiovascular structure position.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 12, 2015
    Inventor: Robert G. Matheny
  • Patent number: 8961602
    Abstract: An adjustable annuloplasty ring includes a body in the form of an endless loop having an internal lumen therethrough, an adjustment suture extending through at least a portion of the internal lumen, a first portion of the suture exiting the lumen through a first opening in the body and a second portion of the suture exiting the lumen through a second opening in the body, and a first adjustment marker on the first portion of the suture outside of the body. The suture may be adapted to reduce the length of the body around the loop when tightened.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: February 24, 2015
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Melinda K. Kovach, Rebecca Volovsek, XueMei Li
  • Publication number: 20150045881
    Abstract: The invention relates to an anchoring device (1, 100) for implanting a prosthetic heart valve at a valve annulus of a patient. According to the invention, such a device comprises: a compressible and expandable sealed ring member (2, 200); a compressible and expandable anchoring element (3, 300) having a ventricular skirt (33, 303) and an atrial skirt (31, 301) linked by a tubular portion (32, 302); said ring member (2, 200) surrounding said tubular portion (32, 302) of said anchoring element (3, 300) and said anchoring element clamping said prosthetic heart valve.
    Type: Application
    Filed: January 10, 2013
    Publication date: February 12, 2015
    Inventor: Pascal Lim
  • Publication number: 20150039084
    Abstract: A medical implant including an anchor portion including a plurality of arms adapted to engage an internal tissue wall of a body from two opposite faces, wherein the anchor portion is configured such that at least one of the arms does not have an entirely overlapping arm on the other side of the wall and an opening portion adapted to define an opening for blood flow through the internal tissue wall, when the anchor portion engages the wall.
    Type: Application
    Filed: January 23, 2007
    Publication date: February 5, 2015
    Inventors: Tamir Levi, Meir Rosenberg, Ori Ben=Amotz, Yoram Rozy, Eyal Benbenisti, Roey Shafrir, Doron Kopelman, Itshak Cohen, Tamar Harel
  • Patent number: 8945210
    Abstract: An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.
    Type: Grant
    Filed: January 8, 2009
    Date of Patent: February 3, 2015
    Assignee: StJude Medical, Cardiology Division, Inc.
    Inventors: Richard G. Cartledge, Leonard Y. Lee
  • Publication number: 20150005875
    Abstract: A cardiac valve prosthesis for implantation at a native valve having leaflets includes a distal fixation member configured to be implanted downstream of a native valve and includes engagement arms configured to apply, to a native valve's downstream side, a first force directed upstream, when the distal fixation member is implanted. The number of engagement arms matches the number of native valve leaflets. The prosthesis also includes a proximal fixation member configured to be implanted at least partially upstream of the native valve such that the proximal fixation member applies, to a native valve's upstream side, a second force directed downstream when the proximal fixation member is implanted. The application of the first and second forces is configured to couple the prosthesis to the native valve. The engagement arms and the proximal fixation member are configured to capture the leaflets of the native valve therebetween.
    Type: Application
    Filed: June 6, 2014
    Publication date: January 1, 2015
    Inventors: Yosi TUVAL, Ido KILEMNIK, Raphael BENARY
  • Publication number: 20140379077
    Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.
    Type: Application
    Filed: September 12, 2014
    Publication date: December 25, 2014
    Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik
  • Patent number: RE45790
    Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: November 3, 2015
    Assignee: JENAVALVE TECHNOLOGY GMBH
    Inventors: Hans-Reiner Figulla, Markus Ferrari, Christoph Damm
  • Patent number: RE45865
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: January 26, 2016
    Assignee: Medtronic CoreValve LLC
    Inventors: Jacques Seguin, Georg Börtlein