Annular Member For Supporting Artificial Heart Valve Patents (Class 623/2.38)
  • Patent number: 10966823
    Abstract: A prosthetic heart valve includes at least one sealing member. The sealing member is adapted to conform to any surface irregularities found on the inner surface of the valve annulus, including any calcium deposits formed on the valve leaflets. The sealing member can be self-expanding or non-expanding. When deployed, the sealing member is adapted to create a blood tight seal between the prosthetic heart valve and the inner surface of the valve annulus thereby minimizing and/or eliminating perivalvular leakage at the implantation site.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: April 6, 2021
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Rakesh M. Suri, W. Andrew Ziarno, Eric Manasse
  • Patent number: 10940303
    Abstract: The various implementations described herein include a percutaneous port for promoting tissue in-growth around the percutaneous port. In one aspect, the percutaneous port includes a tubular structure having an outer surface, and a coil having an outer surface and comprised of a plurality of loops. Furthermore, at least a portion of the outer surface of the coil is joined to the outer surface of the tubular structure.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: March 9, 2021
    Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Guangqiang Jiang, Tom He
  • Patent number: 10926472
    Abstract: An internal tissue including a lesion region in the human body is modeled as a three-dimensional model. By reconstructing thickness or flexibility of a lumen wall portion including the lesion region and making it possible to confirm a motion of the lumen wall or a flow of fluid in the inside of the lumen wall, a state of the lesion region in the lumen can be confirmed clearly by visual inspection or the like. As a result, the diagnosis in the lumen can be made easier.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 23, 2021
    Assignee: TERUMO CORPORATION
    Inventor: Hiroshi Misawa
  • Patent number: 10912644
    Abstract: Systems, devices, and methods for treating a diseased native valve in a patient, the system comprising a compressible and expandable frame structure and an anchor. The anchor comprises a wire having a free end and is configured to be fully advanced from an atrial side of a native valve in a patient into a ventricle of the heart and anchor the frame structure to the native valve when the frame structure is in the expanded configuration adjacent the native valve.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: February 9, 2021
    Assignee: Shifamed Holdings, LLC
    Inventors: Claudio Argento, Andrew Backus, Alice Yang
  • Patent number: 10869764
    Abstract: A venous valve with a tubular frame that includes an outer surface and an inner surface opposite the outer surface and defining a lumen, and a cover over at least the outer surface of the tubular frame, where the cover includes surfaces defining a reversibly sealable opening for unidirectional flow of a liquid through the lumen. A system with the venous valve and a catheter including a proximal end and a distal end, the venous valve located between the proximal end and distal end of the catheter. A method including forming the venous valve and reversibly joining the venous valve and a catheter. A method including positioning at least part of the catheter including the venous valve at a predetermined location and deploying the venous valve from the catheter at the predetermined location.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: December 22, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Susan M. Shoemaker, Jason P. Hill, Paul F. Chouinard, Leonard B. Richardson
  • Patent number: 10769477
    Abstract: Disclosed are a method, an apparatus, a device and a storage medium for extracting a cardiovisceral vessel from a CTA image, including: performing corrosion operation and expansion operation on an image data successively via a preset structural element to obtain a structure template, wherein the image data is a coronary angiography image after a downsampling processing, and the structure template is a structure excluding a pulmonary region; performing a transformation in layer-by-layer on slice images of the structure template to acquire a first ascending aorta structure in the structure template, and acquiring an aorta center coordinate and an aorta radius in the last layer of slice image of the structure template; and establishing a binarized spherical structure according to the aorta center coordinate and the aorta radius, and synthesizing a second ascending aorta structure by combining the first ascending aorta structure with the structure template and the binarized spherical structure.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: September 8, 2020
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Shoujun Zhou, Baochang Zhang, Baolin Li, Cheng Wang, Pei Lu
  • Patent number: 10751174
    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: August 25, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian S. Conklin, Da-Yu Chang
  • Patent number: 10687938
    Abstract: Docking devices can be configured to be positioned at a native valve of a human heart to provide structural support for docking a prosthetic valve. The docking devices generally have coiled structures that define an inner space in which the prosthetic valve can be held. Some docking devices can be adjusted from a first wider configuration which facilitates easier advancement of the docking device around the valve anatomy, to a second narrower configuration after the docking device has been delivered to more securely hold the prosthetic valve. The docking device may also be better held in position at the native valve after adjustment to the narrower configuration. Some docking devices include a stabilization segment or double coil configuration, where a main coil region is configured to securely hold a prosthetic valve, while a stabilization coil region is configured to more stably hold the docking device at the native valve.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: June 23, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Darshin S. Patel, Hernan Altman, Boaz Manash, Tamir S. Levi, Dinesh L. Sirimanne
  • Patent number: 10646361
    Abstract: A method of connecting an expansion ring to at least one end of a braided implant is disclosed. The method can include positioning the braided implant about a tube; everting an end portion of the braided implant over a first end of the tube; assembling an expansion ring to the braided implant, the expansion ring being a multi-leaved expansion ring including clips terminating with an open-ended coupling opening. The openings can be pushed over a set of intersecting wires of the braided implant at respective circumferential locations on or adjacent the first end of the tube. The method can also include closing the openings over the set of intersecting wire; trimming ends of the braided implant; and reversing eversion of the braided implant thereby positioning the expansion ring internal to the braided implant.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: May 12, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Pedro Pedroso, Christopher Krier
  • Patent number: 10543085
    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: January 28, 2020
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Visith Chung, Da-Yu Chang, Brian S. Conklin, Grace Myong Kim, Louis A. Campbell, Donald E. Bobo, Jr., Myron Howanec, Jr., David S. Lin, Peng Norasing, Francis M. Tran, Mark Van Nest, Thomas H. Chien, Harvey H. Chen, Isidro L. Guerrero, Derrick Johnson, Paul A. Schmidt
  • Patent number: 10478289
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: November 19, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider
  • Patent number: 10426604
    Abstract: A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: October 1, 2019
    Assignee: St. Jude Medical, LLC
    Inventor: Peter N. Braido
  • Patent number: 10413401
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: September 17, 2019
    Assignee: MEDTRONIC CV LUXEMBOURG S.A.R.L.
    Inventors: Carol Eberhardt, Gopikrishnan Soundararajan, Kenny Dang, Hussain Rangwala
  • Patent number: 10376680
    Abstract: Devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart of a mammal are disclosed. Devices may include an adjustable hydraulic diameter and/or a removable and/or replaceable shunt portion. Devices may include absorbable materials, the absorption of which directly or indirectly causes alterations of the fluid flow capacities the devices.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: August 13, 2019
    Assignee: Corvia Medical, Inc.
    Inventors: Edward I. McNamara, Michael W. Sutherland, Matthew J. Finch, Stephen J. Forcucci
  • Patent number: 10314693
    Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. A cuff may be coupled to the stent so that a flat, bottom edge of the cuff lies adjacent the proximal end of the stent. A pattern of stitches may be circumferentially disposed around the flat bottom edge of the cuff, the pattern of stitches alternating between stitches sewn to the cuff only and stitches sewn to both the cuff and the stent.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: June 11, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Andrea L. McCarthy, Kent J. Smith
  • Patent number: 10226336
    Abstract: A stented prosthetic heart valve including a stent assembly, a leaflet assembly, and mounting members. The stent assembly includes a stent post frame, a stent post frame covering, and a base frame. The stent post frame includes a continuous rail forming a closed-curved shape defining a longitudinal axis, and a plurality of circumferentially-spaced posts projecting from cusp segments in a direction of the longitudinal axis. The cloth covering encompasses the rail. The base frame supports the cusp segments. The valve leaflet assembly is attached to the stent assembly, and includes a leaflet clamped between one of the cusp segments and the base frame. The mounting members each directly pass through the stent post frame cloth covering, the first leaflet and the base frame. The rail can have a constant cross-sectional shape with a major axis dimension that is greater than a minor axis dimension.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: March 12, 2019
    Assignee: Medtronic, Inc.
    Inventors: Jason Beith, Elliot Howard
  • Patent number: 10130462
    Abstract: An intra-annular mounting frame for an aortic valve having native aortic cusps is provided which includes a frame body with native leaflet reorienting curvatures and interconnecting points; the curvatures shaped to be received inside the valve below the native aortic cusps and to reorient the native aortic cusps within the aortic valve, where each of the curvatures extends concavely upward from a reference latitudinal plane tangential to each curvature's base.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: November 20, 2018
    Assignee: BioStable Science & Engineering, Inc.
    Inventor: J. Scott Rankin
  • Patent number: 10086184
    Abstract: The various implementations described herein include methods used to manufacture a percutaneous port for promoting tissue in-growth around the percutaneous port. In one aspect, the method includes providing a tubular structure having an outer surface and providing a coil having an outer surface and comprised of a plurality of loops. The method further includes joining at least a portion of the outer surface of the coil to the outer surface of the tubular structure.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: October 2, 2018
    Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Guangqiang Jiang, Tom He
  • Patent number: 10080653
    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: September 25, 2018
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian S. Conklin, Da-Yu Chang
  • Patent number: 10052202
    Abstract: A heart valve assembly has a frame comprising an anchoring section, a generally cylindrical leaflet support section, and a neck section that transitions between the anchoring section and the valve support section. The anchoring section has a ball-shaped configuration defined by a plurality of wires that extend from the leaflet support section, with each wire extending radially outwardly to a vertex area where the diameter of the anchoring section is at its greatest, and then extending radially inwardly to a hub. A plurality of leaflets are stitched to the leaflet support section. The heart valve assembly is delivered to the location of a native pulmonary trunk, the vertex area of the anchoring section is deployed into the native pulmonary arteries such that the vertex area is retained in the pulmonary arteries, and then the leaflet support section is deployed in the pulmonary trunk.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: August 21, 2018
    Assignee: Venus Medtech (Hangzhou) Inc
    Inventors: Min Frank Zeng, Pham Lo
  • Patent number: 10052198
    Abstract: A coiled anchor for docking a mitral valve prosthesis at a native mitral valve of a heart has a first end, a second end, and a central axis extending between the first and second ends, and defines an inner space coaxial with the central axis. The coiled anchor includes a coiled core including a bio-compatible metal or metal alloy and having a plurality of turns extending around the central axis in a first position, and a cover layer around the core, the cover layer including a bio-compatible material that is less rigid than the metal or metal alloy of the coiled core.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: August 21, 2018
    Assignee: Mitral Valve Technologies Sarl
    Inventors: Mark Chau, Alexander J. Siegel, Paul A. Spence, Landon H. Tompkins
  • Patent number: 9980814
    Abstract: The kit (10) of the invention includes a valve bearing (16) that can be radially deformed. The bearing (16) includes an outer peripheral wall (22) defining a central passage (40) having an axis (X-X?). The bearing (16) further includes an inner peripheral wall (24) defining an inner lumen (44) having a radial dimension lower than that of the central passage (40). The kit (10) includes a prosthetic valve (18) to be placed on the inner peripheral wall (24). The inner peripheral wall (24) extends in the central passage axially relative to the outer wall (22). The valve bearing (16) includes a means (26) for maintaining the inner peripheral wall (24) radially remote from the outer peripheral wall (22). The inner peripheral wall (24) and the maintaining means (26) define an inner blood circulation region (56) containing the lumen (44) which is tightly isolated from an outer region (58).
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: May 29, 2018
    Assignee: CORMOVE
    Inventor: Mikolaj Styrc
  • Patent number: 9827095
    Abstract: A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: November 28, 2017
    Assignee: HLT, Inc.
    Inventors: Gary A. Thill, Robert Foster Wilson, John P. Gainor, Christopher M. Banick
  • Patent number: 9820851
    Abstract: A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: November 21, 2017
    Assignee: St. Jude Medical, LLC
    Inventor: Peter N. Braido
  • Patent number: 9775704
    Abstract: The present invention provides valve prostheses adapted to be initially crimped in a narrow configuration suitable for catheterization through body ducts to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: October 3, 2017
    Assignee: Medtronic3F Therapeutics, Inc.
    Inventors: Bjarne Bergheim, Keith E. Myers, Jeffrey P. DuMontelle, Christine Nguyen
  • Patent number: 9649192
    Abstract: A method for heart valve surgery may include providing a cardiac valve ring and suture loops connected to the cardiac valve ring, accessing a valve annulus of the heart of the patient, stapling at least one of the sutures loop to the valve annulus, and parachuting the cardiac valve ring down the suture to the valve annulus after the stapling. The cardiac valve ring may be an annuloplasty ring, a replacement heart valve, or other medical device.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: May 16, 2017
    Assignee: Dextera Surgical Inc.
    Inventor: Bernard A. Hausen
  • Patent number: 9622863
    Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: April 18, 2017
    Assignee: Edwards Lifesciences Corporation
    Inventors: Emil Karapetian, Charles Stanislaus, Gregory Bak-Boychuk, Christopher Olson, Cristobal Hernandez, William Brunnett, Netanel Benichou, Lauren Freschauf, Alex Siegel
  • Patent number: 9605534
    Abstract: A system, method and computer-readable medium for monitoring a fluid injection at a downhole location in a wellbore is disclosed. A member is provided in the wellbore. The member includes a passage for flow of fluid and a fiber optic cable including a plurality of temperature sensitive sensors wrapped around the member. A selected temperature signal is imparted into the fluid flowing in the member. A temperature of the fluid exiting the member at the downhole location is measured using the plurality of temperature sensors. The measured temperature and the imparted temperature signal are compared to determine a flow parameter of the injected fluid.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: March 28, 2017
    Assignee: BAKER HUGHES INCORPORATED
    Inventors: Jeff Chen, Luis E. Mendez, Chee M. Chok, Xudong Yang
  • Patent number: 9585749
    Abstract: A replacement heart valve assembly. An expandable anchor is disclosed that has a skirt region, a lip region, and a plurality of posts attached to the skirt region. A replacement heart valve is attached to the posts. The lip region has interlocking elements that are secured to the posts where the interlocking elements have eyelets. Tabs extend into the eyelets to mate with holes in the posts.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: March 7, 2017
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 9539088
    Abstract: A fixation band for affixing a prosthetic heart valve to tissue having proximal and distal annular portions positionable relative to one another, the proximal and distal annular portions each having a proximal and distal sides, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and a prosthetic heart valve being attachable to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device operative between the proximal and distal annular portions for selectively positioning the proximal and distal annular members toward one another for compressing the staples therebetween and deploying the staples into tissue so as to affix the prosthetic heart valve to tissue.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: January 10, 2017
    Assignee: Medtronic, Inc.
    Inventors: Steven B. Woolfson, Richard B. Streeter, Daniel C. Taylor, John R. Liddicoat
  • Patent number: 9526614
    Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a second loop-shaped support, which is configured to abut a second side of the heart valve opposite to said first side, whereby a portion of the valve tissue is trapped between the first and second supports. An outer boundary of the second support is greater than an outer boundary of the first support.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: December 27, 2016
    Assignee: Medtentia International Ltd. Oy
    Inventor: Olli Keränen
  • Patent number: 9474601
    Abstract: A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: October 25, 2016
    Assignee: Medtronic, Inc.
    Inventors: Michael J. Drews, Donnell W. Gurskis, Stephen R. Bacich
  • Patent number: 9393113
    Abstract: A method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a catheter to a vicinity of the heart valve; deploying the anchor from the catheter; expanding the anchor to contact tissue at an anchor site; and retrieving the anchor into the catheter. The invention also includes an apparatus for endovascularly replacing a heart valve, including: a catheter; a replacement valve configured to be disposed within the catheter for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the catheter for delivery to a vicinity of the heart valve, to be deployed from the catheter, to be expanded to contact tissue at an anchor site and to be retrieved back into the catheter after having been expanded.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: July 19, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 9289289
    Abstract: A device for anchoring a prosthetic heart valve on biological tissue, includes first and second anchoring assemblies, mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: March 22, 2016
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Giovanni Rolando, Mauro Ercolani, Paolo Gaschino, Andrea Marchisio
  • Patent number: 9277991
    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: March 8, 2016
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Amr Salahieh, Brian D. Brandt, Dwight P. Morejohn, Ulrich R. Haug, Jean-Pierre Dueri, Hans F. Valencia, Robert A. Geshlider, Jeff A. Krolik
  • Patent number: 9211361
    Abstract: This invention relates to processes of preparing heterogeneous graft material from animal tissue. Specifically, the invention relates to the preparation of animal tissue, in which the tissue is cleaned and chemically cross-linked using both vaporized and liquid cross-linking agents, resulting in improved physical properties such as thin tissue and lowered antigenicity, thereby increasing the ease of delivering the tissue during surgery and decreasing the risk of post-surgical complication, respectively.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: December 15, 2015
    Inventor: Kemal Schankereli
  • Patent number: 9161836
    Abstract: A device for anchoring on biological tissue a prosthetic heart valve, includes first and second anchoring assemblies mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: October 20, 2015
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Giovanni Rolando, Mauro Ercolani, Paolo Gaschino, Andrea Marchisio
  • Patent number: 9066801
    Abstract: Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: June 30, 2015
    Assignee: Medtronic, Inc.
    Inventors: Igor Kovalsky, Ilia Hariton, Yossi Tuval, Nadav Yellin
  • Publication number: 20150127093
    Abstract: Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native chordae tendineae and/or leaflets of a valve. The support member can comprise a flexible, distensible material to reduce abrasion and other mechanical damage to surrounding structures. A locking member may be used to couple both ends of the support member, forming a support ring. The support member may have two magnetic end portions which can be magnetically coupled to form a support ring. An expandable prosthetic heart valve can be delivered into the native heart valve and expanded within the support band, thereby causing one or more of the native chordae tendineae and/or leaflets of the native heart valve to be frictionally secured between the support ring and the expanded prosthetic heart valve.
    Type: Application
    Filed: September 9, 2014
    Publication date: May 7, 2015
    Applicant: Edwards Lifesciences Corporation
    Inventors: Ronald J. Hosmer, Erin M. Spinner
  • Publication number: 20150127100
    Abstract: A prosthetic heart valve may include a stent body with a plurality of cells arranged in circumferential rows and a cuff attached to the stent. A leaflet attachment panel may be attached to and span a portion of one of the cells. A prosthetic valve element, such as a leaflet having a belly, may be mounted to the leaflet attachment panel. The leaflet attachment panel may not be integral with the stent body. A reduced overlap area may be defined between a proximal end of the stent body and a proximalmost point of attachment of the leaflet belly to the cuff. The reduced overlap area may have a size dependent upon the circumferential row of cells the leaflet attachment panel is attached to and a position of the portion of the leaflet attachment panel to which the leaflet is mounted. Alternately, the leaflet may be attached directly to the stent.
    Type: Application
    Filed: November 5, 2014
    Publication date: May 7, 2015
    Inventors: Peter N. Braido, Kent J. Smith
  • Patent number: 9023102
    Abstract: A medical device used in cardiac surgery for replacement of diseased heart valves in humans. A heart valve prosthesis comprising a housing 1 having a projection 3 along its whole perimeter 2, an occluder 4 which restricts the blood backflow (I), and a cuff 5 made of fabric and having a mounting surface 6which comes into contact with cardiac tissues (II), and an outer surface 7 which comes into contact with the blood flow. Inside the cuff 5 are located a stent 8 forming an opening 9 for installation of the prosthesis housing 1, a supporting element 10 and a retaining element 11 which fix the projection 3 of the housing 1 within the stent 8 of the cuff 5 forming a quick-dismountable junction of the housing 1 with the cuff 5.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: May 5, 2015
    Assignee: MedEng
    Inventors: Sergey Vasilyevich Evdokimov, Alexandr Sergeyevich Evdokimov, Eduard Yurievich Goncharov, Alexandr Nikolayevich Filippov
  • Publication number: 20150119982
    Abstract: Mitral valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion. The inflow portion is formed from a plurality of struts that outwardly extend from the first end of the valve-retaining tubular portion with adjacent struts of the plurality of struts being joined, wherein each strut of the plurality of struts has a substantially s-shaped profile and at least one twisted area.
    Type: Application
    Filed: October 21, 2014
    Publication date: April 30, 2015
    Inventors: Jason Quill, Igor Kovalsky
  • Publication number: 20150112427
    Abstract: Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy.
    Type: Application
    Filed: May 2, 2014
    Publication date: April 23, 2015
    Applicant: Caisson Interventional LLC
    Inventors: Cyril J. Schweich, JR., Todd J. Mortier
  • Publication number: 20150112433
    Abstract: Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy.
    Type: Application
    Filed: May 2, 2014
    Publication date: April 23, 2015
    Applicant: Caisson Interventional LLC
    Inventors: Cyril J. Schweich, JR., Todd J. Mortier
  • Publication number: 20150105857
    Abstract: A device useful for implantation at a native heart valve can include an anchor element having a tubular configuration defining a longitudinal direction and a circumference, a heart valve prosthesis disposed within the anchor element, and a plurality of elongate members positioned at equidistant angular intervals about the circumference of the anchor element. The device can be configured to be transitioned from a radially collapsed delivery configuration to a radially expanded implantation configuration, and the plurality of elongate members can have a length extending in the longitudinal direction of the tubular member in the expanded implantation configuration.
    Type: Application
    Filed: December 19, 2014
    Publication date: April 16, 2015
    Applicants: MEDTRONIC VASCULAR GALWAY LIMITED, JENAVALVE TECHNOLOGY GMBH
    Inventors: Philipp BONHOEFFER, Younes BOUDJEMLINE
  • Patent number: 8998982
    Abstract: The invention provides a device for fine adjustment of a prosthetic valve device and a method of adjusting the position of a prosthetic valve after implantation. The adjustment mechanism includes complementary structures on a valve member and device frame that cooperate to provide relative axial and/or angular motion between the valve member and device frame (and thus the native vessel). The adjustment mechanism of the invention may also include a means for selectively maintaining the relative position of the valve member and device frame. The device and method are particularly applicable for use with a modular prosthetic valve device that is assembled in the body lumen.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: April 7, 2015
    Assignee: Valve Medical Ltd.
    Inventors: Yoram Richter, Jacob Richter, Ety Weisz
  • Publication number: 20150094804
    Abstract: A device useful for implantation at a native heart valve can include an anchor element having a tubular configuration defining a longitudinal direction and a circumference, a heart valve prosthesis disposed within the anchor element, and a plurality of elongate members positioned at equidistant angular intervals about the circumference of the anchor element. The device can be configured to be transitioned from a radially collapsed delivery configuration to a radially expanded implantation configuration, and the plurality of elongate members can have a length extending in the longitudinal direction of the tubular member in the expanded implantation configuration.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Applicants: MEDTRONIC VASCULAR GALWAY LIMITED, JENAVALVE TECHNOLOGY GMBH
    Inventors: Philipp BONHOEFFER, Younes BOUDJEMLINE
  • Publication number: 20150094802
    Abstract: The present invention is primarily directed a prosthetic cardiac valve support device adapted for endovascular delivery to a cardiac valve, comprising a single ring-shaped support element having an inner diameter and an outer diameter, wherein said support element has an outer perimeter that is entirely rigid, wherein said support element is fitted with one or more intra-ventricular and/or intra-atrial stabilizing elements, and wherein said support element has a collapsed delivery configuration and a deployed configuration.
    Type: Application
    Filed: August 28, 2014
    Publication date: April 2, 2015
    Inventors: Maurice BUCHBINDER, Shay DUBI, Amit TUBISHEVITZ, Avi EFTEL
  • Patent number: RE45790
    Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: November 3, 2015
    Assignee: JENAVALVE TECHNOLOGY GMBH
    Inventors: Hans-Reiner Figulla, Markus Ferrari, Christoph Damm
  • Patent number: RE45865
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: January 26, 2016
    Assignee: Medtronic CoreValve LLC
    Inventors: Jacques Seguin, Georg Börtlein