Annular Member For Supporting Artificial Heart Valve Patents (Class 623/2.38)
  • Publication number: 20140379077
    Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.
    Type: Application
    Filed: September 12, 2014
    Publication date: December 25, 2014
    Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik
  • Patent number: 8900295
    Abstract: A prosthetic valve assembly and method of implanting same is disclosed. The prosthetic valve assembly includes a prosthetic valve formed by support frame and valve leaflets, with one or more tethers each having a first end secured to the support frame and the second end attached to, or configured for attachment to, to papillary muscles or other ventricular tissue. The tether is configured and positioned so as to avoid contact or other interference with movement of the valve leaflets, while at the same time providing a tethering action between the support frame and the ventricular tissue. The valve leaflets may be flexible (e.g., so-called tissue or synthetic leaflets) or mechanical.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: December 2, 2014
    Assignee: Edwards Lifesciences Corporation
    Inventors: John F. Migliazza, Hugues LaFrance, Harvey H. Chen, Travis Zenyo Oba
  • Patent number: 8845720
    Abstract: A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: September 30, 2014
    Assignee: Edwards Lifesciences Corporation
    Inventor: Brian S. Conklin
  • Publication number: 20140277427
    Abstract: A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends, the entire anchor may loop out from the frame.
    Type: Application
    Filed: March 5, 2014
    Publication date: September 18, 2014
    Applicant: CardiAQ Valve Technologies, Inc.
    Inventors: J. Brent Ratz, Arshad Quadri, Luca Pesce
  • Publication number: 20140277424
    Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end and a distal end, and a collapsible and expandable valve assembly, the valve assembly including a plurality of leaflets connected to at least one of the stent and a cuff. The heart valve further includes a conformable band disposed about the perimeter of the stent near the proximal end for filling gaps between the collapsible prosthetic heart valve and a native valve annulus.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 18, 2014
    Applicant: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventor: John Oslund
  • Publication number: 20140277425
    Abstract: An occluder for sealing gaps between a medical device and adjacent body tissue includes an expandable body configured to fill the gaps between the medical device and the body tissue. The occluder includes a fastener at one end of the body and adapted to couple to a first end of the medical device, and an expandable disk at the other end of the body and adapted to couple to the medical device at a position spaced from the first end.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 18, 2014
    Applicant: AGA MEDICAL CORPORATION
    Inventor: Gregory James Dakin
  • Publication number: 20140277423
    Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly including a plurality of leaflets, the valve assembly being disposed within the stent. The heart valve further includes a plurality of elongated legs each with a first end coupled to the stent and a free end, the elongated legs being configured to transition from an extended configuration to a relaxed configuration. A sealing portion connected to the plurality of legs forms a sealing structure when the legs transition to the relaxed configuration to reduce perivalvular leakage between the implanted valve and surrounding tissue.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 18, 2014
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Yousef F. Alkhatib, Tracee Eidenschink
  • Publication number: 20140277426
    Abstract: An occluder device for occluding a gap between a medical device and adjacent body tissue includes a conformable body having a hollow interior, a leading end and a trailing end; and a port disposed at the trailing end of the body and in fluid communication with the interior of the body.
    Type: Application
    Filed: December 4, 2013
    Publication date: September 18, 2014
    Applicant: AGA MEDICAL CORPORATION
    Inventors: Gregory James Dakin, Peter Nicholas Braido
  • Patent number: 8834564
    Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: September 16, 2014
    Assignee: Medtronic, Inc.
    Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik
  • Publication number: 20140257475
    Abstract: Apparatus is provided for use with a prosthetic valve for implantation at a native valve of a subject, the native valve including at least one native leaflet, the apparatus including (1) a prosthetic valve support, including (a) an upstream support portion, being configured to be placed against an upstream side of the native valve, and having an inner perimeter that defines an opening that is configured to receive the prosthetic valve, and (b) at least one clip (i) comprising at least two clip arms and a clip-controller interface, the clip-controller interface being coupled to at least one of the clip arms, and (ii) being configured to be coupled to a native leaflet of the native valve; and (2) at least one clip controller, reversibly couplable to the clip-controller interface, and configured to facilitate opening and closing of the clip. Other embodiments are also described.
    Type: Application
    Filed: August 5, 2012
    Publication date: September 11, 2014
    Applicant: MITRALTECH LTD.
    Inventors: Yossi Gross, Gil Hacohen, Eran Miller, Yuval Zipory, Tal Reich, Meir Kutzik, Rotem Neeman
  • Publication number: 20140257476
    Abstract: The present invention comprises a novel and safer mechanism of deployment using a self-positioning, self-centering, and self-anchoring method. To embody the present invention, a disk-based valve apparatus allowing the repositioning and retrieval of the implantable valve while working on a dysfunctional valve structure is disclosed. The disk-based valve apparatus may comprise one or more disks, either proximal or distal, a valve-housing component and a valve component. The one or more disks may be either proximal or distal, may be either connected to each other or disconnected from each other and may either be symmetrical or have different shapes and dimensions. The disk-based valve apparatus may be self anchoring, such as anchored by pressure from the one or more disk, or may be anchored using any anchoring.
    Type: Application
    Filed: May 19, 2014
    Publication date: September 11, 2014
    Inventors: Matteo MONTORFANO, Alaide CHIEFFO, Juan F. GRANADA
  • Publication number: 20140243969
    Abstract: A prosthetic heart valve includes a valve assembly mounted to an expandable stent. The prosthetic heart valve includes a cuff coupled to the stent. The cuff includes a pocket formed between an outer side and an inner side of the cuff. The pocket includes a plurality of biocompatible and irreversibly expandable microspheres. After implantation of the prosthetic heart valve into a patient, any gaps existing between the cuff and the native heart valve are exposed to bodily fluid, such as blood. The blood enters the pocket of the cuff through pores in the outer side of the cuff. The blood interacts with the microspheres, causing irreversible expansion of the microspheres. The microspheres expand to fill any gaps between the prosthetic heart valve and the native heart tissue, sealing the gaps and preventing leakage through the gaps.
    Type: Application
    Filed: December 20, 2013
    Publication date: August 28, 2014
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Ramji T. Venkatasubramanian, Euhnee Cho
  • Publication number: 20140236292
    Abstract: A stent for use in a prosthetic heart valve has a plurality of expandable and collapsible closed cells, a portion of which form an annulus section adapted for placement within the annulus of the native heart valve. Anchor features of the stent residing within at least some closed cells are adapted to engage tissue of the heart, including native valve leaflets, the sinotubular junction, or another implanted device when the prosthetic valve is implanted in the heart. The anchor features may help to retain the prosthetic valve in position, without interfering with the opening and closing of the valve leaflets. Furthermore, the anchor features may be configured to allow the stent to be resheathed into a delivery device after the portion of the stent with the anchor feature has expanded out of the delivery device.
    Type: Application
    Filed: January 27, 2014
    Publication date: August 21, 2014
    Applicant: ST. JUDE MEDICAL, INC
    Inventor: Peter N. Braido
  • Patent number: 8808369
    Abstract: A minimally invasive method of implanting a prosthetic aortic valve includes forming a surgical site within a patient's chest that includes a first access port, a second access port, a viewing port and a delivery port. A camera is inserted into the viewing port. The native aortic valve leaflets may each be grasped and removed via tools inserted through the first and second access ports. The prosthetic aortic valve may be delivered through the delivery port to the valve annulus using a delivery device. The prosthetic aortic valve is implanted at the valve annulus and the delivery device is withdrawn. A surgeon may perform the remotely operated steps while viewing images provided by the camera.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: August 19, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Rakesh M. Suri
  • Publication number: 20140228946
    Abstract: Embodiments of an apparatus for treating a deficient mitral valve include an expandable spacer configured for placement between the native leaflets of the mitral valve, the spacer anchorable to a wall of the ventricle. Methods and apparatus for delivering and implanting the prosthetic are also described.
    Type: Application
    Filed: April 17, 2014
    Publication date: August 14, 2014
    Applicant: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Mark Chau, Marlowe E. Patterson, Seung-Beom Yi, Stephen C. Geist, Travis Oba
  • Publication number: 20140222144
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Application
    Filed: February 1, 2013
    Publication date: August 7, 2014
    Applicant: Medtronic CV Luxembourg S.a.r.l
    Inventors: Carol Eberhardt, Gopikrishnan Soundararajan, Kenny Dang, Hussain Rangwala, Mark Torrianni, Eric Richardson, Kshitija Garde
  • Publication number: 20140200662
    Abstract: An intracardiac device comprising a ring-shaped body and one or more anchoring or stabilizing elements attached to said body, said elements being selected from the group consisting of levered anchoring arms, elongate anchoring arms, and lateral extension elements, wherein said device is able to move between two conformations, a collapsed conformation suitable for insertion into a delivery catheter, and an open conformation, suitable for implantation at a cardiac valve annulus.
    Type: Application
    Filed: January 15, 2014
    Publication date: July 17, 2014
    Inventors: Avi Eftel, Maurice Buchbinder, Shay Dubi, Amit Tubishevitz
  • Publication number: 20140200663
    Abstract: The present invention relates to a medical apparatus for the therapeutic treatment of an insufficient cardiac valve (3a, 3b). The aim of the present invention is to specify a medical apparatus which enables the therapeutic treatment of an insufficient cardiac valve, such as, for example, the mitral valve (3a) or the tricuspid valve (3b), which is arranged between a ventricle (1a, 1b) and an atrium (2a, 2b) of the heart, in a manner as simple as possible and as gentle as possible for the patient in a minimally invasive intervention. For this purpose, the medical apparatus according to the present invention comprises at least one valve means (10) which is designed to prevent in the implanted condition of the medical apparatus a systolic venous reflex return of blood from the atrium (2a, 2b) of the heart into at least one vein (4a, 4a?, 4b, 4b?, 4c, 4c?) which belongs to a venous system (4) which leads into the atrium (2a, 2b) of the heart.
    Type: Application
    Filed: March 14, 2014
    Publication date: July 17, 2014
    Applicant: JenaValve Technology, Inc.
    Inventors: Markus FERRARI, Hans-Reiner FIGULLA
  • Publication number: 20140194983
    Abstract: Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion.
    Type: Application
    Filed: January 8, 2013
    Publication date: July 10, 2014
    Applicant: MEDTRONIC, INC.
    Inventors: Igor Kovalsky, Ilia Hariton, Yossi Tuval, Nadav Yellin
  • Publication number: 20140194975
    Abstract: A method for treating paravalvular leakage at a location of a stented prosthetic valve includes the steps of delivering a clip to a location adjacent chordae tendinae of a native valve, and deploying the clip such that the clip captures at least some of the chordae tendinae of the native valve, thereby increasing tension in the captured chordae tendinae. The clip is delivered to the location in a collapsed stated and is released from a sheath convert to an undeflected or relaxed state. After the clip is released from the sheath, the clip is rotated to capture the chordae tendinae. The clip is then released from the delivery system and the delivery system is retracted.
    Type: Application
    Filed: January 8, 2013
    Publication date: July 10, 2014
    Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.
    Inventors: Jason Quill, Paul Rothstein
  • Publication number: 20140194982
    Abstract: In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.
    Type: Application
    Filed: January 8, 2013
    Publication date: July 10, 2014
    Applicant: MEDTRONIC, INC.
    Inventors: Igor Kovalsky, Jason Quill, Daniel Glozman, Ilia Hariton, Yossi Tuval, Nadav Yellin
  • Patent number: 8771340
    Abstract: Provided are methods, devices, and systems that can be used to deploy prosthetic devices within a bodily lumen of a patient. These methods and devices can include the securement of a prosthetic valve within a vascular lumen by driving one or more fasteners from a position on an expandable device through the valve and into or through a vascular wall.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: July 8, 2014
    Assignee: Cook Medical Technologies LLC
    Inventor: Eric D. Densford
  • Patent number: 8771346
    Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex. The prosthesis includes a distal fixation member, configured to be positioned in a downstream artery, and shaped so as to define exactly three proximal engagement arms that are configured to be positioned at least partially within respective ones of semilunar sinuses, and, in combination, to apply, to tissue that defines the semilunar sinuses, a first axial force directed toward a ventricle. The prosthesis further includes a proximal fixation member coupled to the distal fixation member, the proximal fixation member configured to be positioned at least partially on a ventricular side of the native semilunar valve, and to apply, to the ventricular side of the native valve complex, a second axial force directed toward the downstream artery, such that application of the first and second forces couples the prosthesis to the native valve complex.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: July 8, 2014
    Assignee: Medtronic Ventor Technologies Ltd.
    Inventors: Yosi Tuval, Ido Kilemnik, Raphael Benary
  • Publication number: 20140172086
    Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 19, 2014
    Applicant: CARDIAQ VALVE TECHNOLOGIES, INC.
    Inventors: Arshad Quadri, J. Brent Ratz
  • Publication number: 20140172085
    Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 19, 2014
    Applicant: CardiAQ Valve Technologies, Inc.
    Inventors: Arshad Quadri, J. Brent Ratz
  • Publication number: 20140163672
    Abstract: A prosthetic heart valve comprises a biological tissue valve and a collapsible and expandable support frame having a longitudinal axis. The frame comprises an outflow circumferential structure defining an outflow end of the frame and consisting essentially row of diamond-shaded expandable cells. The frame also comprises three V-shaped structures spaced apart from the outflow circumferential structure and three struts longitudinally aligned with the longitudinal axis of the frame. The three struts are configured to facilitate mounting the biological tissue valve to the frame and interconnect the outflow circumferential structure to the three V-shaped structures. The frame also includes three undulating structures, each of the three undulating structures interconnecting respective adjacent V-shaped structures of the three V-shaped structures. The prosthetic heart valve is configured to be collapsed for introduction into a patient using; a catheter and to be expanded for deployment at an implantation site.
    Type: Application
    Filed: February 11, 2014
    Publication date: June 12, 2014
    Applicant: Medtronic Corevalve LLC
    Inventors: Jacques SEGUIN, Georg BORTLEIN
  • Patent number: 8747463
    Abstract: Devices for fixturing a prosthesis to a first mass and methods of making and using the same are disclosed. Complementary fixturing devices and methods of making and using the same are also disclosed. The devices can be used to attach a heart valve gasket body to a biological annulus.
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: June 10, 2014
    Assignee: Medtronic, Inc.
    Inventors: Thomas J. Fogarty, Michael J. Drews, Ernest Lane, Neil Holmgren, Federico Gutierrez
  • Patent number: 8734507
    Abstract: A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: May 27, 2014
    Assignee: Medtentia International Ltd. Oy
    Inventor: Olli Keränen
  • Publication number: 20140128968
    Abstract: An implantable prosthetic valve assembly having a frame comprising a first frame portion and a second frame portion connected end-to-end exhibits enhanced rigidity. Each frame portion includes a plurality of circumferential struts formed with multiple bends, with the bends of the first frame portion having angles that are less than the bends of the second frame portion. Some embodiments of the frame have a semi-collapsed state in which the first frame portion is frustoconical and the second frame portion is generally cylindrical. A valve member is attached to the first frame portion.
    Type: Application
    Filed: January 14, 2014
    Publication date: May 8, 2014
    Applicant: Edwards Lifesciences Corporation
    Inventors: Netanel Benichou, Benjamin Spenser, Assaf Bash
  • Publication number: 20140088694
    Abstract: A prosthetic valve system for replacing a native aortic valve exhibiting regurgitation comprises a support structure and a transcatheter heart valve (THV) that is separate from the support structure. The support structure is radially collapsible and expandable, and deployable on an outflow side of the native aortic valve, circumscribing the native leaflets of the aortic valve. The THV is radially collapsible and expandable, and deployable in an annulus of the native aortic valve to frictionally engage the native leaflets between an interior surface of the support structure and the THY.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 27, 2014
    Applicant: Edwards Lifesciences Corporation
    Inventors: Stanton J. Rowe, Francesco Maisano, Oded Meiri
  • Publication number: 20140088698
    Abstract: Methods are provided for generating intraluminal prosthetic implants designed to fit onto specific anatomical locations within regions which are stable in terms of their motion in time.
    Type: Application
    Filed: September 20, 2013
    Publication date: March 27, 2014
    Applicant: Materialise N.V.
    Inventors: Toon Roels, Peter Verschueren
  • Publication number: 20140081394
    Abstract: A medical device for holding a cardiac valve implant is disclosed comprising an elongate support defining a peripheral edge with a curvature about which the cardiac valve implant can be fitted, wherein the elongate support comprises a resilient portion for resiliently holding the cardiac valve implant in place in said device, and a support tool for holding a cardiac valve implant comprising first and second elongate support members being separate and radially movable in relation to each other, each having a curvature about which said cardiac valve implant can be fitted and a manipulator portion connected to said first and second elongate support members.
    Type: Application
    Filed: May 4, 2012
    Publication date: March 20, 2014
    Applicant: Medtentia International Ltd. OY
    Inventors: Olli Keränen, Jani Virtanen
  • Patent number: 8673001
    Abstract: A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: March 18, 2014
    Assignee: StJude Medical, Cardiology Division, Inc.
    Inventors: Richard G. Cartledge, Leonard Y. Lee
  • Publication number: 20140074229
    Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).
    Type: Application
    Filed: September 6, 2013
    Publication date: March 13, 2014
    Applicant: JenaValve Technology, INc.
    Inventors: Hans-Reiner FIGULLA, Markus FERRARI, Christoph DAMM
  • Patent number: 8657872
    Abstract: Methods and apparatus are provided for repairing or replacing a defective cardiac valve including an anchor having a double helix configured to engage the cardiac valve leaflets of a diseased or defective cardiac valve, and a replacement valve body disposed in an expandable stent configured to be disposed within the anchor so that the anchor limits expansion of the expandable stent. The expandable stent of the replacement valve body may be self-expanding or mechanically expanded, e.g., using a balloon catheter or catheter-based mandrel and the valve body may be formed of animal tissue or a synthetic fabric.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: February 25, 2014
    Inventor: Jacques Seguin
  • Patent number: 8647254
    Abstract: An epicardial clip for reshaping the annulus of the mitral valve of a heart. The epicardial clip includes a curved member having an anterior segment configured to be positioned in the transverse sinus of the heart, a posterior segment configured to be positioned on the posterior side of the heart, such as on or inferior to the atrioventricular groove, and a lateral segment extending between the anterior segment and the posterior segment. The lateral segment includes a curve such that the first end of the member is positioned at or above the plane of the mitral valve and the second end of the member is positioned at or below the plane of the mitral valve.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: February 11, 2014
    Assignee: Maquet Cardiovascular LLC
    Inventors: Peter Tachi Callas, Pierluca Lombardi, Michael C. Stewart, Liming Lau, Mark S. Juravic, Evan Anderson, Joe Lamberti, Albert K. Chin, Tammy Wang
  • Publication number: 20140012373
    Abstract: Embodiments of a method for implanting a prosthetic valve at the native mitral valve region of the heart, the prosthetic valve including a main body that is radially compressible to a radially compressed state and self-expandable from the compressed state to a radially expanded state. The prosthetic apparatus also comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body with a leaflet-receiving space between the anchor and an outer surface of the main body to receive a native valve leaflet. Apparatus for delivering and implanting the prosthetic valve are also described.
    Type: Application
    Filed: September 12, 2013
    Publication date: January 9, 2014
    Applicant: Edwards Lifesciences Corporation
    Inventors: Mark Chau, Marlowe E. Patterson, Seung-Beom Yi, Stephen C. Geist, Travis Oba, David L. Hauser
  • Patent number: 8623080
    Abstract: A method of using a prosthetic heart valve assembly can include implanting a first prosthesis directly into a native annulus. The first prosthesis can have a central longitudinal axis and a first engagement element. The method can also include engaging the first engagement element of the first prosthesis with a second engagement element of a second prosthesis to securely couple the second prosthesis to the first prosthesis. The second prosthesis can have a prosthetic valve. The first engagement element engages the second engagement element by moving the second prosthesis towards the first prosthesis in a direction generally parallel to the central longitudinal axis until the first engagement element engages the second engagement element.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: January 7, 2014
    Assignee: Medtronic, Inc.
    Inventors: Thomas J. Fogarty, Michael J. Drews, Neil Holmgren, D. Bruce Modesitt
  • Patent number: 8579955
    Abstract: An apparatus and method of use are disclosed for treating, preventing and terminating arrhythmias. In particular, the apparatus is implantable within or on various tissues and structures and is used to prevent or block conduction of aberrant impulses. A variety of methods of the present invention may be used to attack arrhythmias by short-circuiting impulses, inducing fibrosis, ablating tissue or inducing inflammation. In addition, the device and methods may also be used to treat aneurysms. The device may also be used to treat hypertension, and to function as a blood pressure regulator.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: November 12, 2013
    Assignee: Syntach AG
    Inventors: Robert S. Schwartz, Robert A. Van Tassel, David R. Holmes, Jr.
  • Patent number: 8579964
    Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: November 12, 2013
    Assignee: Neovasc Inc.
    Inventors: Randy Matthew Lane, Colin A. Nyuli
  • Patent number: 8568477
    Abstract: Disclosed is a stentless transluminally implantable heart valve, having a formed in place support. The formed in place support exhibits superior crush resistance when compared to conventional balloon expandable or self expandable stent based valves.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: October 29, 2013
    Assignee: Direct Flow Medical, Inc.
    Inventors: Randall T. Lashinski, Gordon B. Bishop
  • Publication number: 20130282114
    Abstract: Heart valve assembly systems and methods configured for medical interventional procedures. In one aspect, the methods and systems involve a modular approach to treatment.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 24, 2013
    Inventors: Cyril J. Schweich, JR., Todd J. Mortier
  • Patent number: 8551162
    Abstract: Biologically implantable prostheses and methods of using the same are disclosed. In one embodiment, a heart valve assembly includes a first annular prosthesis sized for introduction into a tissue annulus in a heart; a first magnet in the first prosthesis; a second valve prosthesis separate and disconnected from the first prosthesis and comprising a heart valve crown with leaflets, the second prosthesis configured for introduction into the tissue annulus after introducing the first prosthesis into the tissue annulus; and a second magnet in the second prosthesis, wherein an attraction between the first magnet and the second magnet engages the first prosthesis to the second prosthesis to attach the second prosthesis to the first prosthesis in the tissue annulus.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: October 8, 2013
    Assignee: Medtronic, Inc.
    Inventors: Thomas J. Fogarty, Michael J. Drews, Neil Holmgren, D. Bruce Modesitt
  • Publication number: 20130253642
    Abstract: A replacement heart valve, including a securing device and a non-return valve, the securing device including a resiliently deformable material adapted to adopt collapsed and non-collapsed configurations, the resiliently deformable material having a memory such that it returns to the non-collapsed configuration when not held under tension, whereby the valve is adapted to be secured within the valve annulus. Also featured is a method for replacing a heart valve and a kit, which use this replacement heart valve.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 26, 2013
    Inventor: Stephen Brecker
  • Patent number: 8529621
    Abstract: The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterized in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than ¾.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: September 10, 2013
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ottavio Alfieri, Francesco Maisano, Alberto Redaelli
  • Patent number: 8523939
    Abstract: A method for heart valve surgery may include providing a cardiac valve ring and suture loops connected to the cardiac valve ring, accessing a valve annulus of the heart of the patient, stapling at least one of the sutures loop to the valve annulus, and parachuting the cardiac valve ring down the suture to the valve annulus after the stapling. The cardiac valve ring may be an annuloplasty ring, a replacement heart valve, or other medical device.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: September 3, 2013
    Assignee: Cardica, Inc.
    Inventor: Bernard A. Hausen
  • Patent number: 8506625
    Abstract: A prosthetic mitral heart valve including a contoured sewing ring that better matches the mitral valve annulus. The sewing ring includes an inflow end and an outflow end, the outflow and having at least one raised portion. There may be two raised portions located approximately 120° apart from each other and designed to register with two anterior trigones of the mitral valve annulus. The sewing ring may be formed by a suture-permeable annular member surrounded by a fabric covering, the annular member desirably being molded of silicone. The raised portion(s) may gently curve upward to a height of about 2 mm above the adjacent portions of the outflow end of the sewing ring. The sewing ring may also be constructed so as to be more flexible around a posterior aspect than around an anterior aspect to accommodate calcified tissue more commonly found around the posterior annulus. The contoured sewing ring can be combined with various types of heart valve including bioprosthetic and mechanical valves.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: August 13, 2013
    Assignee: Edwards Lifesciences Corporation
    Inventor: Derrick Johnson
  • Patent number: 8496700
    Abstract: A device for replacement of a bioprosthetic valve having an annulus (104) and one or more leaflets (105), the device having an outer housing (106) and an inner shaft (108) with a distal end (110). The outer housing (106) is slideable relative to the inner shaft (108) such that a portion of the inner shaft (108) may be revealed. A cap (112) is associated with the distal end (110) of the inner shaft (108), the cap (112) movable between a first position adjacent the inner shaft (108) and a second position displaced from the inner shaft (108). The cap (112) is adapted to trap a skirted valve frame (102) between said cap (112) and the inner shaft (108) when in the first position. The skirted valve frame (102) may be released by the cap (112) upon sliding of the outer housing (106) relative to the inner shaft (108) to reveal the inner shaft (108) and upon movement of the cap (112) to the second position. Also disclosed are associated methods.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: July 30, 2013
    Assignee: Edrich Health Technologies, Inc.
    Inventors: John K. Edoga, Thierry Richard
  • Publication number: 20130190865
    Abstract: A percutaneous prosthetic heart valve assembly comprising a radially expandable anchor docking member, the anchor docking member having an unexpanded state and an expanded state, in the expanded state, the anchor docking member comprising a mechanism for receiving and engaging an implantable heart valve and a bioabsorbable gasket member disposed about the anchor docking member, the bioabsorbable gasket member comprising a bioabsorbable polymer material, the bioabsorbable gasket member having an unexpanded and an expanded state.
    Type: Application
    Filed: January 23, 2013
    Publication date: July 25, 2013
    Applicant: Boston Scientific Scimed, Inc.
    Inventor: Boston Scientific Scimed, Inc.
  • Publication number: 20130190866
    Abstract: A method includes positioning an anchor deployment manipulator at least partially within a lumen of a sleeve of an annuloplasty ring, the sleeve having a lateral wall shaped to define the lumen, and the lumen extending longitudinally along a length of the sleeve. A portion of the sleeve that contains a distal end of the deployment manipulator is placed into an atrium in a vicinity of an annulus of an atrioventricular valve. An anchor is deployed from the distal end of the deployment manipulator through the lateral wall of the sleeve into cardiac tissue, while the distal end of the deployment manipulator is positioned such that a central longitudinal axis of the deployment manipulator through the distal end of the deployment manipulator forms an angle of between 45 and 90 degrees with the lateral wall of the sleeve at a point at which the anchor penetrates the lateral wall.
    Type: Application
    Filed: January 24, 2013
    Publication date: July 25, 2013
    Applicant: VALTECH CARDIO, LTD.
    Inventor: VALTECH CARDIO, LTD.