Abstract: The present invention relates to a method of implanting a prosthesis device in a subject. In one embodiment, this method involves: (i) providing a prosthesis device to be attached to an exposed surface of a bone; (ii) applying bone cement in liquid form to a bone-implant interface region, the bone-implant interface region including a region between the exposed surface of the bone and an outer surface of the prosthesis device; and (iii) contacting the bone cement to the exposed surface of the bone and the outer surface of the prosthesis device under conditions effective to allow the bone cement to cure, thereby resulting in attachment of the prosthesis device to the bone of the subject. The present invention also relates to a kit for implanting a prosthesis device in a subject, a method of performing a joint arthroplasty surgical procedure, and other methods of using bone cement in liquid form.

Abstract: An article coated with an electrolytically deposited bio-compatible composite layer useful as an internal prosthetic device is disclosed. The bio-compatible composite coating that is electrolytically deposited onto the article comprises hydroxyapatite and chitosan. The introduction of chitosan into the crystal matrix of brushite/hydroxyapatite significantly improves the adhesive and chemical and mechanical stability properties of the coating.

Abstract: Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The textured surface is produced by exposing the substrate to an etching fluid comprising a hydrohalic acid and a mixture of a hydrohalic acid and an oxyacid, a chloride containing compound, and an oxidant. The etching solution can be used at ambient temperature. This textured surface enhances adherence of coatings or cells onto the textured surface, improves the retention of proteins on the surface, and encourages bone in-growth.

Abstract: An endoprosthesis utilizes a biomechanical structure based on the lever model of first degree. Contrary to the widespread practice, the inventive structure has a stem placed inside the femur bone, which is not rigidly attached to this bone. Accordingly, the bone, following its known tendency to slightly pivot away from the medial plane of the body in response to the loads, does not directly contact the stem. The neck portion experiences even greater loads then the stem. The supporting anchor has a region extending laterally from the stem and pressing against a supporting surface of the housing, which also extends laterally from the body of the housing. Since the stem, supporting anchor and neck are typically constitute a one-piece component, the lateral surfaces of the supporting anchor and housing are in continuous frictional contact during displacement of the stem and housing relative to one another.

Abstract: An artificial joint is capable of harmoniously connecting the artificial joint, cement and a bone and facilitating effusion of the cement at the time of implantation, as well as diminishing the stress applied thereto. The artificial joint includes a head, a neck and a stem, the stem being coated in advance with cement so as to easily bond the cement to cement filled in a bone cavity of a human femur. An effusion path for effusing the cement filled in the bone cavity is formed in a longitudinal direction on a surface of the cement coated on the stem so that the cement filled in the bone cavity of the human femur can be easily effused upward through the effusion path when the stem is inserted.