Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

Abstract: Methods for total ankle replacement procedures are disclosed. A method includes making an initial incision, obtaining an alignment guide, performing an alignment, performing a tibia and talar resection, trialing the implant components, performing a talar chamfer resection, and implanting the components.

Abstract: A coating for an implant component, in particular a component of a spinal implant, is provided. The coating is a ceramic titanium nitride coating comprising an at % content of 5 to 30 At % of Ag in addition to an at % content of Ti and an at % content of N.

Abstract: An implant for insertion into a patient is provided. The implant includes a three-dimensionally printed structure of layers. Each layer comprises an infill pattern of the three-dimensionally printed structure, the infill pattern of each layer comprising a set of infill lines. The implant includes a plurality of hollow channels. The layers are arranged on top of one another such that the plurality of hollow channels are formed within the implant, wherein the walls of each channel are formed by sections of the infill lines of a plurality of layers of the printed structure of layers. At least one hollow channel extends between a first outer surface of the implant and a second outer surface of the implant. At least one hollow channel is oriented in a direction which is tilted with respect to a reference axis perpendicular to the first outer surface of the implant.

Abstract: A method of treating or preventing a microbial infection in a patient is provided, along with a wound irrigation system and a composition in the form of an irrigation liquid for reducing microbial load or preventing microbial infection in a wound.

Abstract: A bone screw implant is provided for immobilizing the articular surfaces of two bone segments by securing, fusing, or compression the two segments. The implant may be fabricated from a porous biocompatible metal and have a cylindrical shape and fully or partially threaded and may have variable pitch threads and a variable diameter of the shaft. The implant may include a blunt tip or a fluted self-drilling tip and a headless screwdriver socket. Large pitch cancellous threads may be in the leading-end portion of the cylinder shaft, and smaller pitch cortical threads may be at the trailing edge portion of the shaft. The implant may be fenestrated, it may have a roughened surface, and it may be coated with an osteoconductive material. The implant may be cannulated. In a specific embodiment, the implant is used for immobilizing the articular surfaces of a sacroiliac joint. The implant may be coated with hydroxyapatite or tricalcium phosphate at thickness of 100 nm to 100 ?m thick.

Abstract: A stemless humeral component for replacing the humeral head of a patient's humerus includes a support flange having a number of cantilevered legs extending distally away from a bottom surface thereof. Instruments and methods for surgically installing the stemless humeral component are also disclosed.

Abstract: Embodiments herein relate to an implant for insertion into a patient. The implant comprises a plurality of unit cells arranged to form a three-dimensional lattice structure, the three-dimensional structure comprising a resting volume of the implant. The plurality of unit cells are arranged to form a porous network of the three-dimensional structure, and wherein the three-dimensional structure is a reversibly compressible three-dimensional structure, wherein a bulk porosity of the three-dimensional structure of the implant is at least 50%. Also disclosed is a method of tissue reconstruction or tissue augmentation. The method comprises implanting into the body of a subject an implant of the disclosure.

Abstract: A method of treating or preventing a microbial infection in a patient is provided, along with a wound irrigation system and a composition in the form of an irrigation liquid for reducing microbial load or preventing microbial infection in a wound.

Abstract: Once variation of a system for total knee replacement includes: a first alignment guide defining first set of guides that locate a first set of pins on a first bone of a joint in extension and defining a reference surface relative to the first set pin guides; a second alignment guide constrained relative to the first alignment guide by the reference surface and defining a second set of guides, relative to the first set of guides, that locate a second set of pins on a second bone of the joint; a first cut guide located by the first set of pins and defining a first cut plane for resecting the first bone; and a second cut guide located by the second set of pins and defining a second cut plane, linearly offset from the first cut plane, for resecting the second bone.

Abstract: A glenoid implant for a shoulder prosthesis for implantation in the glenoid of a scapula according to embodiments of the present invention includes a central fixation element; an articular body configured for articulation with a humerus, the articular body comprising a plate, the plate comprising a side configured to be oriented toward the glenoid, the side comprising a central protrusion, wherein the central fixation element comprises a means for mechanically engaging with the central protrusion; a first means for locking rotation of the central fixation element with respect to the glenoid; and a second means for locking rotation of the articular body with respect to the glenoid.

Abstract: A model production device generates one or more contact bodies of a patient-specific surgical instrument model based on a parameterized model of a patient's bone. The parameterized model includes a predetermined number of polygons each having a predetermined position relative to the patient's anatomy. The parameterized model may be generated based on a three-dimensional model that was generated based on multiple images of the patient's bone. The model production device adds parametric fixed geometry to the patient-specific surgical instrument model based on the parameterized model and subtracts the three-dimensional model of the patient's bone from the patient-specific surgical instrument model. Each contacting body may be positioned at a high-confidence part of the parametric model, and the parametric fixed geometry may be positioned at a low-confidence part. A patient-specific surgical instrument may be manufactured based on the patient-specific surgical instrument model.

Abstract: In one aspect, a system and method for aligning hip replacement prostheses comprises an acetabular liner having an inner concave surface and an outer convex surface. The acetabular liner includes at least two magnetic sensors arranged in a spatially distributed manner. The system and method also include a prosthetic femoral component comprising a femoral head component. The femoral head component and the acetabular liner component are shaped such that a ball and socket joint is formed when the femoral head component comes into contact with the inner concave surface of the acetabular liner. While the ball-and-socket joint is formed, and in at least some orientations of the femoral head component relative to the acetabular liner component, a contact point on an external surface of the femoral head component contacts the inner concave surface. The femoral head component includes at least one permanent magnet.

Abstract: A system and method may use a robotic arm to perform a range of motion test for use in generating information related to kinematic alignment in a total or partial knee arthroplasty. A method may include controlling a robotic arm to move a tibia throughout a range of motion for a knee. A series of measurements of gap distance for the knee may be used to determine a tibial resection location for the tibia. The method may include updating a plan (e.g., 3D, preoperative) for an orthopedic procedure on the knee with the tibial resection location.

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

Abstract: A soft actuator includes an inflation chamber. The inflation chamber has a first end and a second end opposite the first end. The inflation chamber is inflatable during an inflation stage, in which the second end rotates toward the first end about a folding axis, and is operable to be loaded during an inflated stage, in which the inflation chamber is inflated. The soft actuator also includes a variable-stiffness hinge located between the first end and the second end along the folding axis. The variable-stiffness hinge has a decreased stiffness in the inflation stage and an increased stiffness in the inflated stage.

Abstract: An implant system includes a first portion, a second portion, and a third portion. The first portion includes a hydrogel; the second portion includes a porous material and the hydrogel in pores of the porous material; and the third portion includes the porous material. The first portion is free of the porous material and the third portion is free of the hydrogel. The third portion has non-uniform lateral cross-section.

Abstract: A system and method that acquire (i) at least a reference image including one of a preoperative image of a surgical site with skeletal and articulating bones and a contralateral image on an opposite side of the patient from the surgical site, and (ii) at least an intraoperative image of the site after an implant has been affixed to the articulating bone. The system preferably generates at least one reference stationary point on at least the skeletal bone in the reference image and at least one intraoperative stationary point on at least the skeletal bone in the intraoperative image. The location of the implant is identified in the intraoperative image, preferably including the position of first and second centers of rotation, which are digitally represented and copied into the reference image to analyze at least one of offset and length differential.

Abstract: A hemi-prosthesis implant comprises a replacement-joint part with an articulation surface for tribological pairing with a joint surface of a natural joint counterpart. The articulation surface is embodied with a coating applied on a substrate. The substrate provides a relief for the adhesion of the coating. The relief may comprise one or more of a plurality of grooves, a plurality of teeth, a ribbing, and a roughened surface. The relief may be embodied entirely or partially outside the articulation surface. The replacement joint part may optionally comprise a ventilation feature, and the articulation surface may be formed by injection molding on the substrate. The hemi-prosthesis implant may be part of an implant set that includes both a hemi-prosthesis implant and a total prosthesis implant, either of which can be chosen intraoperatively.

Abstract: A joint replacement balancing system which provides real-time feedback to a surgeon during a joint replacement surgery to assist the surgeon to balance a joint replacement. The joint replacement balancing system includes a non-transitory processor-readable medium storing code representing instructions to cause a processor to receive a signal from a joint balancing apparatus, determine if the joint replacement is out of balance, determine a corrective course of action to bring the joint into balance and generate and display to the surgeon during the joint replacement surgery a recommended corrective course of action to complete the joint replacement surgery.

Abstract: Embodiments herein relate to an implant for insertion into a patient. The implant comprises a plurality of unit cells arranged to form a three-dimensional lattice structure, the three-dimensional structure comprising a resting volume of the implant. The plurality of unit cells are arranged to form a porous network of the three-dimensional structure, and wherein the three-dimensional structure is a reversibly compressible three-dimensional structure, wherein a bulk porosity of the three-dimensional structure of the implant is at least 50%. Also disclosed is a method of tissue reconstruction or tissue augmentation. The method comprises implanting into the body of a subject an implant of the disclosure.

Abstract: A method for forming a polyethylene and alumina nanocomposite coating on a substrate is described. The method may use microparticles of UHMWPE with nanoparticles of alumina to form a powder mixture, which is then applied to a heated steel substrate to form the nanocomposite coating. The nanocomposite coating may have a Vickers hardness of 10.5-12.5 HV.

Abstract: Systems and methods for performing an osteotomy are presented. Examples include forming a fusion osteotomy at a metatarsocuneiform joint of the first ray of a human foot.

Abstract: A method for detecting biometric parameters includes the steps of performing a bone graft procedure on at least one vertebra of a spine, providing at least one biometric sensor at the at least one vertebra, the sensor measuring at least one parameter selected from the group consisting of pressure, tension, shear, relative position, and vascular flow in an adjacent, surrounding, and measuring the at least one biometric parameter at the vertebra with the sensor.

Abstract: The disclosure relates to methods of making an osteoconductive polymer article for use as an orthopedic implant comprises steps of forming an article from a biocompatible, non-biodegradable polymer, the article comprising a non-flat surface with roughness Ra of at least 5 ?m; providing a dispersion of bioactive ceramic particles of particle size at most 10 ?m in a first solvent comprising a solvent for the polymer; coating at least the non-flat surface with the dispersion in at least one step; and rinsing the coated article with a second solvent being a non-solvent for the polymer to substantially remove the first solvent. Further disclosed is an osteoconductive polymer article for use as an orthopedic implant, which article is made from a biocompatible, non-biodegradable polymer and comprises a non-flat surface with roughness Ra of at least 5 ?m, wherein bioactive ceramic particles of particle size at most 10 ?m are partly embedded in the polymer at the surface of the article.

Abstract: An innovative dome toe resurfacing system for performing metatarsophalangeal joint replacement is disclosed. The present invention comprises a prosthetic implant for metatarsophalangeal joint, and one or more cone extensions that covers portions of the prosthesis that extends into the metatarsal bone and phalanx bone. The cone extensions include a plurality of ridges that will catch bone on insertion and provide a press fit. The present invention also includes a cone and cup reaming system wherein one or more reamers will ream a cone/cup shape for the articular surfaces, and prepare the metatarsal and phalangeal canals for the insertion of the cone extensions. The cone extensions have ends that fit the reamed cone/cup shape wherein the cone/cup shape resembles the natural anatomy of articular surfaces of metatarsophalangeal joint.

Abstract: An interbody spacer is provided including a body portion defining a longitudinal axis. The body portion includes a distal end portion, a proximal end portion, opposed side surfaces that extend between the distal and proximal end portions, and top and bottom surfaces configured and adapted to engage vertebral bodies. The interbody spacer includes first orifices defined through the top surface. The first orifices include orifices having first and second cross-sectional configurations and the first orifices are arranged in rows extending along the longitudinal axis.

Abstract: Disclosed herein are systems and methods for bone preparation with designed areas having accurate tolerance profiles to enable improved initial fixation and stability for cementless implants and to improve long-term bone ingrowth/ongrowth to an implant. One method includes preparing a bone surface to receive a prosthetic implant thereon by resecting the bone surface using a first cutting path to create a first resected region and resecting the bone of the patient using a second cutting path to create a second resected region at least partially overlapping the first resection region. The second cutting path is different than the first cutting path and either manual or robotic cutting tools can be used for creating the first and second resected regions.

Abstract: A method and system for minimizing rolling database recovery downtime. Specifically, the disclosed method and system entail migrating and recovering database data from backup storage to local host storage while enabling database access operations through live mounts mapped to the database data on the backup storage. Database downtime may subsequently be reduced through the rapid switching of file system references between database data stored on backup storage and database data copies recovered on local storage.

Abstract: Photodynamic devices for replacement of an articular head of a bone are provided. In an embodiment, a photodynamic device includes a photodynamic support member and an articular member attachable, either fixedly or removably, to the photodynamic support member and having a bearing surface. In an embodiment, the articular member includes a recess designed to receive the photodynamic support member. In an embodiment, the photodynamic support member includes an opening into which a shaft of the articular member can be inserted to attach the articular member to the photodynamic support member.

Abstract: The invention provides new devices for implantation in a patient having irregular textured surfaces, which devices show significantly improved cellular response compared to conventional smooth and textured implants, indicating that significantly improved biocompatibility would be achieved in vivo. Methods for making such new devices and surface textures are also disclosed.

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

Abstract: A medical device for implantation in a hip joint and fixated to the pelvic bone of a patient is provided. The medical device has an inner and an outer surface. A contacting portion, of the inner surface is spherical and adapted to face the center of the hip joint when the medical device is implanted. The medical device is adapted to receive a caput femur or a prosthetic caput femur which has a spherical portion. The medical device has at least one extending portion, extending the contacting portion of the inner surface such that the at least one extending portion clasps the spherical portion of the caput femur or a prosthetic caput femur, such that the spherical portion is restrained in the medical device. Restraining the caput femur in the medical device reduces the risk that the hip joint dislocates when in use by the patient.

Abstract: A bone screw implant is provided for immobilizing the articular surfaces of two bone segments by securing, fusing, or compression the two segments. The implant may be fabricated from a porous biocompatible metal and have a cylindrical shape and fully or partially threaded and may have variable pitch threads and a variable diameter of the shaft. The implant may include a blunt tip or a fluted self-drilling tip and a headless screwdriver socket. Large pitch cancellous threads may be in the leading-end portion of the cylinder shaft, and smaller pitch cortical threads may be at the trailing edge portion of the shaft. The implant may be fenestrated, it may have a roughened surface, and it may be coated with an osteoconductive material. The implant may be cannulated. In a specific embodiment, the implant is used for immobilizing the articular surfaces of a sacroiliac joint.

Abstract: A method for removing an implant attached to a bone during revision joint replacement surgery includes a library of implant models. A series of surface points are collected on the implant with a digitizer. A best match is computed between the collected surface points and an implant model in the library of implant models to register the position of the implant model to the implant. A location is computed of a material-implant interface based on the geometry of the implant model and the registered position of the implant model. Material is removed at the material-implant interface to separate the implant from the bone. A computer-assisted surgical system is provided for performing the method.

Abstract: The glenoid implant comprises a baseplate, an articular component which has a convex articular surface, and a platform which is provided both to be secured to the articular component by a first attachment and to be secured to the baseplate by a second attachment, the first attachment being independent from the second attachment and defining an assembly axis along which the platform and the articular component are assembled together. The first attachment comprises both a translational connection that is intraoperatively operable to prevent translation between the platform and the articular component along the assembly axis, and a rotational connection that is intraoperatively operable to prevent rotation between the platform and the articular component around the assembly axis, the translational connection and the rotational connection being distinct from each other.

Abstract: The present invention relates to a composition containing a metal powder for three-dimensional printing, a three-dimensional printing method using the same as a raw material, and a three-dimensional printing device, which enable a metal product, which requires high precision as well as high strength, to be produced by a three-dimensional printing technique using a raw material containing a metal powder as a feedstock for three-dimensional printing. In particular, the composition containing a metal powder for three-dimensional printing, according to the present invention, is used as a feedstock supplied to an extrusion head of a three-dimensional printer, and is produced by kneading, pulverizing, and pelletizing the metal powder and a polymer binder.

Abstract: A data processing method, performed by a computer, for determining implant positions of two implant components relative to two bones, wherein each of the implant components is to be attached to one of the bones such that the implant components form a joint between the bones, and wherein an implant position is a relative position between the implant component and the corresponding bone, said method comprising the steps of: a) acquiring a set of target poses, wherein a target pose represents a relative position to be achieved between the two bones; b) calculating a set of virtual poses for a pair of virtual test implant positions, wherein the set of virtual poses comprises one virtual pose for each of the target poses and wherein a virtual pose represents a relative position between the two bones if the virtual test implant positions were applied as the implant positions; c) calculating a pose deviation value for each of the target poses, wherein a pose deviation value represents the difference between a tar

Abstract: An implantable medical device, such as an intervertebral spacer, may comprise a polymeric component and a metallic component. The metallic component can contain both porous metal and substantially-solid metal. The polymeric material can contain particles of an osseointegrative material. The metallic component can be more protruding toward bone than the polymeric component while having a smaller dimension of roughness than the polymeric component. In embodiments, the pin may press-fit against substantially solid metal. The porous metal may surround solid metal which in turn may surround the pin. The pin may have a press-fit with metal and a looser fit with polymeric component, if the metal components and polymeric components are trapped. A pin may connect superior and inferior metal components by a press-fit. The central opening may be exposed to porous metal and also to substantially-solid metal and to polymer. Specific geometries of implants are disclosed.

Abstract: An orthopaedic surgical instrument system includes a tibial base trial and a tibial insert trial. An insert adaptor is sized to be positioned in an aperture defined in the tibial insert trial. The insert adaptor includes a base sized to be positioned over a post of the tibial base trial and a locking tab positioned in the base and configured to engage the post of the tibial base trial.

Abstract: Prosthetic devices and methods of controlling the same are provided. A prosthetic ankle device includes a foot unit and lower limb member moveable relative to one another and defining an ankle angle therebetween. The prosthetic ankle device further includes a controller to operate the device based on weight shifting. Methods of controlling the prosthetic ankle device include operating the device at different ankle angles depending on weight shifting of the user while standing or stopped.

Abstract: A system and method for detecting lubrication conditions, lubrication regimes, impingement, stick-slip, and/or surface damage allows the health of a joint to be monitored. The system and method provides in situ or in vivo real-time monitoring of dynamic and static conditions of the joint. The monitoring system may use both passive and active sensing approaches that employ strategically placed piezoelectric transducers on/in the articulating components of the joint. In some embodiments, the transducers may be Lead Zirconate Titanate (PZT) transducers. Active sensing may be used to detect lubrication regimes under static and dynamic conditions. Passive sensing may be used to characterize the joint motion and abnormities, such as impingements and surface damages.

Abstract: This set comprises glenoid components that each include a body defining, on two of its opposite faces, respectively, a joint surface, intended to cooperate with a humeral head, and a bearing surface bearing against the socket of a shoulder blade. In this set, the glenoid components are provided in several different sizes, respectively defined by the dimensions of the joint surface of their body. At least two glenoid components of which the bearing surfaces respectively have different dimensional geometries are provided so as to allow the surgeon to improve the durability of the mechanical cooperation between the implanted component and the operated socket.

Abstract: A prosthetic device for use as an artificial meniscus is disclosed. The prosthetic device restores shock absorption, stability, and function to the knee joint after removal of the damaged natural meniscus. In some embodiments, the prosthetic device is pre-tensioned to improve the fit of the prosthetic device within the knee joint and, thereby, maximize the contact area of the load-bearing surfaces to distribute loading through the prosthetic device in a manner substantially similar to that of a healthy natural meniscus. In some embodiments, the pre-tensioned prosthetic device is smaller, or scaled-down, relative to the size of a healthy natural meniscus.

Abstract: Disclosed herein are systems and methods for bone preparation with designed areas having accurate tolerance profiles to enable improved initial fixation and stability for cementless implants and to improve long-term bone ingrowth/ongrowth to an implant. A method of preparing a bone surface to receive a prosthetic implant thereon having an articular surface and a bone contacting surface includes resecting the bone surface at a first location to create a first resected region having a first tolerance profile with a first cross-section, resecting the bone surface at a second location to create a second resected region having a second tolerance profile with a second cross-section less dense than the first cross-section, and contacting the bone contacting surface of the prosthetic implant with the first resected region.

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

Abstract: The disclosure includes methods and systems for making orthopedic connections where there is unique adjustability to the connection. Illustratively, one embodiment provides a connecting assembly for connecting a plurality of orthopedic components. Such connecting assemblies can include a first orthopedic component that provides a female bore. Additionally the assembly can include a second orthopedic component that can be or include a male-type connecting member that is positionable in the bore of the first orthopedic component. In one preferred form, the male-type connecting member will be a quasi-spherical member. The quasi-spherical member can include a textured outer surface, e.g., for contacting one or more walls or surfaces in the bore in a fashion that removeably locks or helps to removeably lock or fix the quasi-spherical member in the bore.

Abstract: A modular reverse shoulder orthopedic implant includes a humeral stem component and a separable fracture epiphysis component having a number of suture holes formed therein. The fracture epiphysis component is configured to receive a number of sutures for surgically repairing a proximal humeral fracture.

Abstract: A method of stabilizing a patient's ulnohumeral joint including the steps of: obtaining a stabilizing assembly having a mounting portion and a buttressing portion; and implanting the stabilizing assembly into an operative position wherein the mounting portion of the stabilizing assembly is anchored at a proximal region of the patient's ulna and the buttressing portion is situated to abut the patient's humerus so as to limit subluxation at the ulnohumeral joint while allowing movement between the patient's ulna and humerus at the patient's ulnohumeral joint.

Abstract: A data processing method, performed by a computer, for determining implant positions of two implant components relative to two bones, wherein each of the implant components is to be attached to one of the bones such that the implant components form a joint between the bones, and wherein an implant position is a relative position between the implant component and the corresponding bone, said method comprising the steps of: a) acquiring a set of target poses, wherein a target pose represents a relative position to be achieved between the two bones; b) calculating a set of virtual poses for a pair of virtual test implant positions, wherein the set of virtual poses comprises one virtual pose for each of the target poses and wherein a virtual pose represents a relative position between the two bones if the virtual test implant positions were applied as the implant positions; c) calculating a pose deviation value for each of the target poses, wherein a pose deviation value represents the difference between a target