Having Textured Outer Surface Patents (Class 623/23.5)
  • Patent number: 10474134
    Abstract: Methods and systems for predicting deformation error and compensating for shape deviation in Additive Manufacturing (AM) techniques include, in one aspect, a method including: obtaining a deformation model for an AM machine; predicting deformation for the object using the deformation model applied to the 3D model; selecting an amount of deformation compensation to effect by minimizing deviation for the predicted deformation; and providing the selected amount of deformation compensation to modify the 3D model to compensate for deformation during creation by the AM machine.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: November 12, 2019
    Assignee: University of Southern California
    Inventors: Qiang Sean Huang, He Luan, Yuan Jin
  • Patent number: 10449051
    Abstract: An implant includes a body having a leading edge portion, a trailing edge portion, and an intermediate portion extending between the leading edge portion and the trailing edge portion. The leading edge portion includes a substantially smooth surface forming a substantial majority of a leading edge surface of the leading edge portion. The trailing edge portion includes a monolithic structure including at least one receptacle configured to receive an insertion tool. In addition, the intermediate portion includes a plurality of elongate curved structural members.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: October 22, 2019
    Assignee: Institute for Musculoskeletal Science and Education, Ltd.
    Inventors: Rami Hamzey, Robert Morris, William Duffield, Edward J. McShane, III, Megan A. Stauffer, Mathew Gordon, Joseph M. Nyahay
  • Patent number: 10405962
    Abstract: A method for making a polymer with a porous layer from a solid piece of polymer is disclosed. In various embodiments, the method includes heating a surface of a solid piece of polymer to a processing temperature and holding the processing temperature while displacing a porogen layer through the surface of the polymer to create a matrix layer of the solid polymer body comprising the polymer and the porogen layer. In at least one embodiment, the method also includes removing at least a portion of the layer of porogen from the matrix layer to create a porous layer of the solid piece of polymer.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: September 10, 2019
    Assignee: Vertera, Inc.
    Inventors: Wei-Hsiang Chang, Stephen Lee Laffoon, Christopher S. D. Lee, David Lee Safranski
  • Patent number: 10251730
    Abstract: The present invention provides an implant body formed from metal or ceramics as a raw material, the implant body including a modified surface, provided with a plurality of projections and a plurality of crevasse-like nanoscale grooves, by which focal adhesion formation, penetration of collagen fibers, arrangement of the collagen fibers in a single direction to thereby adhere to connective tissue, and soft tissue sealablity are possible. According to such a surface modification, focal adhesion formation and the arrangement of the cell cytoskeleton can be enhanced, and penetration of collagen fibers into the surface internal portion is possible.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: April 9, 2019
    Assignee: IMPLANT AND TISSUE ENGINEERING DENTAL NETWORK-TOKYO, LIMITED CO
    Inventor: Eiji Kato
  • Patent number: 10130492
    Abstract: An intervertebral implant frame that is configured to engage a spacer can include a pair of arms that extend longitudinally from a support member such that the arms engage the spacer. The spacer can be made from bone graft, and include a first spacer body made of cortical bone, and a second spacer body made of cancellous bone.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: November 20, 2018
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Kurt Schmura, Edwin Chan, Benjamin Chronister, Raymond Murphy, Michael Jacene
  • Patent number: 9993345
    Abstract: A provisional femoral component, in one embodiment, including at least one first visual indicator and at least one second visual indicator, the first and second visual indicators providing indicating means for simultaneously visually representing a first profile of a first femoral prosthesis and a second profile of a second femoral prosthesis. In another embodiment, a provisional femoral component including a patellofemoral flange having two sulci and a central ridge between the two sulci. In this manner, the provisional femoral component can be positioned on a resected distal femur surface of both a right and left knee joint.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: June 12, 2018
    Assignee: Zimmer, Inc.
    Inventors: Nolan C. Jones, Jeffery A. VanDiepenbos, Abraham Habegger, Brian D. Earl
  • Patent number: 9867718
    Abstract: An intervertebral implant frame that is configured to engage a spacer can include a pair of arms that extend longitudinally from a support member such that the arms engage the spacer. The spacer can be made from bone graft, and include a first spacer body made of cortical bone, and a second spacer body made of cancellous bone.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: January 16, 2018
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Kurt Schmura, Edwin Chan, Benjamin Chronister, Raymond Murphy, Michael Jacene
  • Patent number: 9682170
    Abstract: A high-strength coating for dental and orthopedic implants utilizing hydroxyapatite (HAp) nanoparticles provides for a high level of osseointegration through a range of surface pore sizes in the micro- to nanoscale. Zinc oxide (ZnO) nanoparticles may be incorporated with the HAp nanoparticles to form a composite coating material, with ZnO providing infection resistance due to its inherent antimicrobial properties. A textured surface, consisting of “islands” of roughly square coating structures measuring about 250 ?m on a side, with spacing of 50-100 ?m therebetween, may further promote the osseointegration and antimicrobial properties of the implant coating.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: June 20, 2017
    Assignees: The Board of Trustees of the University of Arkansas, NanoMech, Inc.
    Inventors: Ajay P. Malshe, Wenping Jiang
  • Patent number: 9504550
    Abstract: A method for making a polymer with a porous layer from a solid piece of polymer is disclosed. In various embodiments, the method includes heating a surface of a solid piece of polymer to a processing temperature and holding the processing temperature while displacing a porogen layer through the surface of the polymer to create a matrix layer of the solid polymer body comprising the polymer and the porogen layer. In at least one embodiment, the method also includes removing at least a portion of the layer of porogen from the matrix layer to create a porous layer of the solid piece of polymer.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: November 29, 2016
    Assignee: VERTERA, INC.
    Inventors: Wei-Hsiang Chang, Stephen Lee Laffoon, Christopher S. D. Lee, David Lee Safranski
  • Patent number: 9254194
    Abstract: A transdermal intraosseous device includes a transdermal adapter for an external prosthetic device for a bone of a patient and a bone fixator including a distal portion coupled to the transdermal adapter and a proximal portion for anchoring into the bone. The transdermal adapter includes a dome-shaped portion for transcutaneous implantation and an external shaft extending from the dome-shaped portion. A dermal transition structure is configured to include a controlled roughness gradient from the external shaft to the dome-shaped portion and configured for use in infection control at a dermis layer of the patient.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: February 9, 2016
    Assignee: BIOMET MANUFACTURING, LLC
    Inventors: Joshua R. Porter, Troy W. Hershberger
  • Patent number: 9023419
    Abstract: A high-purity porous metal coating is formed over a substrate by thermal spraying a metal coating material over the desired portion of the substrate in an atmospheric air environment. The metal coating material may react with the atmosphere to cause impurities in the applied coating. The impurity-rich portion of the applied coating is subsequently removed to form the high-purity porous metal coating. Process steps are included that cause the impurity-rich portion of the applied coating to be a surface portion that is removable to arrive at the high-purity coating. A protective shroud may be used to limit the amount of impurity imparted to the applied coating and/or a getter material may be employed to continually bring impurities toward the surface of the coated substrate during coating.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: May 5, 2015
    Assignee: Hitemco Medical Application Inc.
    Inventors: Michael Meehan, Jinlong Wang, John Whalen, Edwin Garafalo, Rick Montalbano
  • Patent number: 9015922
    Abstract: An implant device for humans or mammals has a body structure having an exposed surface and one or more selected portions of the exposed surface having a bone formation enhancing 3-dimensional pattern. The exposed surface can be on exterior portions of the body structure or internal portions of the body structure or both. The one or more selected portions of the exposed portions having the bone formation enhancing 3-dimensional patterns are in the external exposed surfaces or in the internal exposed surfaces or both internal and external exposed surfaces.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: April 28, 2015
    Assignee: Vivex Biomedical, Inc.
    Inventor: Timothy Ganey
  • Patent number: 8992615
    Abstract: An in-bone implantable shaft for prosthetic joints or for direct skeletal attachment of external limb prostheses, comprised of a central body fitted in the zone of the bone's medullary cavity conventionally prepared for implantation, and of side elements attached to the central body and fitted in the slots specially made in the bone's walls surrounding said medullary canal; said side elements have spaces between them, arranged to be filled by bone cells to provide a natural and safe osseolocking of the shaft. A method of preparing the bone for implantation of a prosthetic shaft, comprising the steps of: placing a cylindrical guide with slots made in the longitudinal direction of said guide inside said bone's canal which is conventionally prepared for implantation; cutting said bone's walls by progressing a saw along the edges of the slots of said guide; removing the guide; fitting the shaft in the bone's canal, provided that the side elements are fitted to the slots in the bone's walls.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: March 31, 2015
    Inventor: Mark Pitkin
  • Publication number: 20150088267
    Abstract: A bone augment for filling a void in a bone and providing secure fixation of an implant to the bone includes a sidewall structure having a top surface, a first end and a second end. The sidewall structure rises from a base of the bone augment. The first end of the bone augment is disposed opposite to the second end of the bone augment. An insertion aperture is disposed within the bone augment and extends from the first end of the bone augment to the second end of the bone augment. The bone augment receives a bone plate within the insertion aperture and the bone plate fixes the bone augment within the void.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 26, 2015
    Inventor: Frank A. LIPORACE
  • Publication number: 20150032220
    Abstract: An orthopedic implant system includes a wedge implant. The implant includes a body having an upper surface extending generally in a first plane. The upper surface has a first plurality of longitudinal grooves and a second plurality of transverse grooves extending therealong. Portions of the upper surface extend between adjacent longitudinal grooves and transverse grooves form individual peaks. A lower surface extends generally in a second plane, parallel to the first plane. The lower surface has a third plurality of longitudinal grooves and a fourth plurality of transverse grooves extending therealong. Portions of the lower surface extend between adjacent longitudinal grooves and transverse grooves form individual peaks.
    Type: Application
    Filed: October 14, 2014
    Publication date: January 29, 2015
    Inventors: Jeffrey Tyber, Christopher Faresich
  • Patent number: 8936638
    Abstract: This invention provides a method for producing bioactive coral bone graft substitutes and to products obtained thereby.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: January 20, 2015
    Assignees: Ramot At Tel-Aviv University Ltd., Corebone Ltd.
    Inventors: Ohad Schwartz, Itzhak Binderman
  • Patent number: 8932663
    Abstract: Methods for forming bone implants for the repair of the ends of bones at orthopedic joints, which implants have a Young's modulus close to that of human cortical bone. Substrates of dense isotropic graphite are coated overall with hard, microporous, isotropic pyrocarbon of specific character such that it can be polished to serve as an articular surface and can also securely receive an anchoring first metal layer through PVD. The first layer has a character such that, by thermal spraying a second biocompatible metal layer thereupon, fusion occurs and thereby anchors an outermost layer that is formed with a network of randomly interconnected pores and a surface character of peaks and valleys designed to promote enhanced appositional growth of cortical bone at the interface therewith.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: January 13, 2015
    Assignee: Ascension Orthopedics, Inc.
    Inventors: Joseph P. Ritz, Clive Scott
  • Publication number: 20150012107
    Abstract: The present application is directed to the field of implants comprising processed hard or soft biological tissues for use in implantation in humans. The molded biological tissue implants of the present application are preferably made from allograft soft tissue sources and demineralized bone matrix. The present application provides biological implants exhibiting advantageous properties of absorption, expansion, resiliency and shape retention. The properties of the biological implants produced by the methods of the present application are leveraged in the creation and development of novel biological implant constructs and of novel methods of treatment and surgical technique.
    Type: Application
    Filed: September 22, 2014
    Publication date: January 8, 2015
    Inventors: Keith Cameron Koford, Nathaniel Scott Long, Erica Lee Scharringhausen, Randall Keith Hilliard
  • Publication number: 20140358238
    Abstract: A bioabsorbable plug implant, suitable for bone tissue regeneration, comprising a first portion, and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material. A method for bone tissue regeneration comprising the steps of: providing a bioabsorbable plug implant, wherein the implant comprises a first portion and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material; inserting the second portion into a defect or gap of a bone, the first surface engaging the outside contour of the defect or gap; allowing the plug implant to contact body fluids, thereby expanding the size of the plug implant so that the plug fits into the defect or gap.
    Type: Application
    Filed: March 24, 2014
    Publication date: December 4, 2014
    Applicant: OSTEOPORE INTERNATIONAL PTE LTD.
    Inventors: Swee Hin TEOH, Kim Cheng TAN, Dietmar HUTMACHER, Thiam Chye LIM, Jan-Thorsten SCHANTZ, Ning CHOU
  • Patent number: 8888862
    Abstract: A bone implant comprises a core 10 having an integral anchoring structure 12 at its surface. The structure 12 comprises an array of upwardly extending mutually spaced pointed claw-like teeth 14 for digging into bone to which the implant is to be attached, and a network of pores 16 underlying the array and communicating with the exterior of the surface via openings 18 between the teeth, the pores allowing for the circulation of nutrients to promote bone growth.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: November 18, 2014
    Inventors: Patrick McDonnell, Noel Harrison
  • Patent number: 8888860
    Abstract: A prosthesis comprising: an inner layer (4) formed from a polyaryletherketone; a first outer layer (2a) adjacent to said inner layer formed from a porous polyaryletherketone, at least some of said pores having located therein material to promote osteointegration; and a second outer layer (2b) adjacent to said first outer layer formed from a porous polyaryletherketone, a portion of said pores being free of material to promote osteointegration. The invention also relates to a method of manufacture of the prosthesis.
    Type: Grant
    Filed: February 3, 2011
    Date of Patent: November 18, 2014
    Assignee: Finsbury (Development) Limited
    Inventor: Andrew Clive Taylor
  • Patent number: 8876910
    Abstract: A method for selectively dissolving the beta (?) phase of a titanium alloy out of the surface of the alloy, thereby leaving behind a nano-scale porous surface having enhanced bonding properties with either a biological tissue, such as bone, or an adhesive material, such as a polymer or ceramic by immersing the alloy in an ionic aqueous solution containing high levels of hydrogen peroxide and then exposing the alloy to an electrochemical voltage process resulting in the selective dissolution of the beta phase to form a nano-topographic metallic surface.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: November 4, 2014
    Assignee: Syracuse University
    Inventors: Jeremy Gilbert, Zhijun Bai, Nithya Chandrasekaran
  • Patent number: 8877499
    Abstract: A biocompatible implantable bone anchor is provided that has a threaded first portion that engages and anchors into a bone. The implant also has a neck region extending from the first portion adapted to promote autologous cell growth thereon at an interface of the bone and one or more epidermal or gum layers, the neck region having a plurality of channels extending about the neck region. The neck region is configured to mechanically engage at least one of an abutment, dental restoration, or osseous device attachment. An in situ bone anchor cell growth assembly includes the bone anchor and a manifold encompassing the neck portion so as to form a seal therebetween and a route of fluid communication between a manifold inlet and at least one of said plurality of channels. A process for growing autologous cells on a neck region of a bone anchor is provided.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: November 4, 2014
    Assignee: ViaDerm LLC
    Inventors: Allen B. Kantrowitz, Michael N. Helmus
  • Publication number: 20140316533
    Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
    Type: Application
    Filed: June 30, 2014
    Publication date: October 23, 2014
    Inventors: Pierre DESCOUTS, Björn-Owe ARONSSON, Michael GRÄTZEL, Carine VIORNERY, Peter PÉCHY
  • Publication number: 20140288662
    Abstract: The present invention comprises devices, systems, and methods for elongating bone using an extension implant having a first end and a second end. The first end of the extension implant is inserted into an opening in the live bone and the second end of the extension implant is combined with an enlarged implant. A plurality of channels extend through the components to serve as conduits for delivering fluids and physiological signals which induce bone formation. Some embodiments include a subcutaneous cage assembly for helping to support the implant as the bone heals around it.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 25, 2014
    Applicant: Osteoceramics, Inc.
    Inventor: Thomas D. McGee
  • Publication number: 20140277559
    Abstract: Hard-tissue implants are provided that include a bulk implant, a face, pillars, and slots. The pillars are for implantation into a hard tissue. The slots are to be occupied by the hard tissue. The hard-tissue implant has a Young's modulus of elasticity of at least 10 GPa, has a ratio of the sum of (i) the volumes of the slots to (ii) the sum of the volumes of the pillars and the volumes of the slots of 0.40:1 to 0.90:1, does not comprise any part that is hollow, and does not comprise any non-pillar part extending to or beyond the distal ends of any of the pillars. Methods of making and using hard-tissue implants are also provided.
    Type: Application
    Filed: May 28, 2014
    Publication date: September 18, 2014
    Inventor: George J. Picha
  • Publication number: 20140271779
    Abstract: Synthetic, bioactive ultra-porous bone graft materials having an engineered porosity, and implants formed from such materials are provided. In particular, these implants comprise bioactive glass and incorporate allograft material for osteoinduction. The implants are suitable for bone tissue regeneration and/or repair.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Applicant: PROSIDYAN, INC.
    Inventors: Charanpreet S. BAGGA, Steve B. JUNG, Hyun W. BAE
  • Patent number: 8834576
    Abstract: Fired magnesium oxide stabilized zirconia ceramic body having a highly smooth, polished or otherwise equivalent surface has, on at least part of the surface, a metal/metal alloy coating. The fired ceramic body can be a magnesium oxide stabilized tetragonally toughened zirconia. The coating can be from a metal or metal alloy other than by tantalum vapor deposition, and can include a titanium metal or alloy. The coated magnesium oxide stabilized zirconia ceramic can be a tool or an orthopedic implant or component for an orthopedic implant, which can be a load bearing implant or component for a load bearing implant having an articular surface and a nonarticular surface where the metal or metal alloy coating is on at least part of the nonarticular surface. Plasma arc spraying under vacuum may be employed.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: September 16, 2014
    Inventor: Louis A. Serafin, Jr.
  • Publication number: 20140200667
    Abstract: Implants for osteo and osteochondral repair have been developed. These implants include a series of channels between the upper and lower surfaces of the implants, such that when implanted the lower surfaces are situated in an area rich in bone marrow and the channels provide a means for the bone marrow to migrate through the implant. Preferably the implants are made from resorbable polymer fibers, preferably arranged in braids that are knitted or woven together such that the braids are substantially parallel with each other. The implants may be rolled into a bundle of braids with the axis of the braids substantially parallel to the axis of the bundle, to provide channels along the axis of the bundle. A preferred embodiment includes P4HB fibers braided and knitted into a structure that is coated with a ceramic, preferably physiologic calcium phosphate.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 17, 2014
    Applicant: Tepha, Inc.
    Inventor: Andrew J. Carter
  • Publication number: 20140195001
    Abstract: High strength implantable devices having complex surfaces are injection molded from powder metal wherein the surface is defined by a monolithic insert made by additive manufacturing. The insert defines the surface texture of the device and may also include a portion to form an ingrowth texture and a portion to form a substrate interface texture. The tensile bond strength of the texture is 20 Mega Pascal or greater.
    Type: Application
    Filed: January 8, 2014
    Publication date: July 10, 2014
    Applicant: Praxis Power Technology, Inc.
    Inventor: Joseph A. Grohowski, JR.
  • Publication number: 20140188242
    Abstract: The present invention provides a cancellous bone scaffold to use in the replacement or repair of connective tissue such as ligaments and tendons. The cancellous bone scaffold has a fully demineralized segment with at least one adjacent mineralized end segment.
    Type: Application
    Filed: March 5, 2014
    Publication date: July 3, 2014
    Inventors: Eric A. Nauman, Darryl A. Dickerson
  • Publication number: 20140155356
    Abstract: A novel composition, kit, and method of using the composition as a bone substitute for dental, orthopedic and drug delivery purposes. Specifically, the bone substitute comprises a plurality of polymeric beads having a crosslinkable shell where the shell is cured by light and/or chemical curing.
    Type: Application
    Filed: November 30, 2012
    Publication date: June 5, 2014
    Applicant: A Enterprises, Inc.
    Inventor: A Enterprises, Inc.
  • Patent number: 8734889
    Abstract: The invention relates to a ceramic implant, especially a dental implant, comprising a structured or porous surface for at least partially inserting into a bone. An especially advantageous surface is obtained when it is at least partially modified by a salt melt. These excellent osteointegration properties can be obtained by a method whereby the surface is modified in a salt melt at least in the regions exposed to the bones and/or soft tissue, optionally following a previous modification of the surface whereby material has been removed.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: May 27, 2014
    Assignee: Thommen Medical AG
    Inventors: Falko Schlottig, Thomas Hefti
  • Publication number: 20140131909
    Abstract: A biologic artificial bone includes an artificial fiber material formed from a synthetic polymer with mechanical properties similar to type I collagen. A biocompatible liquid substance is impregnated in the fiber material that hardens and stiffens the fiber material. A bone substitute is impregnated in the hardened and stiffened fiber material forming an artificial bone composite. Vascular channels are formed in the artificial bone composite to facilitate in-growth of vessels and bone forming cells. The construction and methods achieve an artificial composite structure that is similar to natural bone with comparable properties.
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Inventor: Said G. Osman
  • Publication number: 20140121772
    Abstract: Bone implant compositions and methods are provide that have a first surface and a second surface, the first surface and the second surface comprising a demineralized bone matrix and having a plurality of perforations configured to receive demineralized bone; and a third surface of the bone implant comprising cortical bone, the third surface disposed between the first surface and the second surface. The bone implant compositions and methods provided are osteoinductive and allow rapid bone fusion.
    Type: Application
    Filed: October 25, 2012
    Publication date: May 1, 2014
    Applicant: WARSAW ORTHOPEDIC, INC.
    Inventors: Kelly Brook Emerton, Susan J. Drapeau
  • Publication number: 20140058526
    Abstract: Porous regions are formed using selected additive manufacturing techniques. The porous regions can assist in fibro-inductive regions and/or osteo-inductive regions. A prosthetic member can be formed completely with the additive manufacturing technique and/or the additive manufacturing techniques can be used to form an augment portion that is added to the prosthetic member formed separately.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 27, 2014
    Applicant: Biomet Manufacturing Corporation
    Inventors: Jason D. Meridew, Joshua R. Porter
  • Publication number: 20140025179
    Abstract: Reticulated composites are formed with a thin coating of a ductile biocompatible metal such as tantalum on a brittle biocompatible substrate such as vitreous carbon. Such composites exhibit physical properties that permit these monolithic composites to be morselized, or sized and shaped manually. Such composites exhibit surfaces with excellent ductile metal biocompatibility properties, but with strength and fracture physical properties that are more characteristic of the brittle substrate than of the ductile metal. Such composites fracture easily, and may be morselized or worked by manual sizing and shaping. Such morselization and working is accomplished by breaking or fracturing the composite, rather than plastically deforming it. Morselized or manually shaped reticulated composites exhibit excellent biocompatibility characteristics with micro- and nano-textured surfaces that promote rapid bone ingrowth and adhesion. When the composite is broken, the substrate is exposed.
    Type: Application
    Filed: March 14, 2013
    Publication date: January 23, 2014
    Applicant: Ultramet
    Inventors: Arthur J. Fortini, Richard Kaplan, Gregory Borwick
  • Patent number: 8632604
    Abstract: A medical implant device comprises a substrate (10) having an undulating surface provided by peaks (12) which are separated by recesses (14). The device includes a porous coating layer provided on the undulating surface of the substrate which comprises a plurality of particles (16). The spacing between adjacent peaks on the surface of the substrate is less than the particle size of the particles. The particles are bonded to the peaks on the surface of the substrate and adjacent particles are bonded to one another.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: January 21, 2014
    Assignee: Depuy International Limited
    Inventor: James Brooks
  • Publication number: 20140005793
    Abstract: The present application is directed to the field of implants comprising processed hard or soft biological tissues for use in implantation in humans. The molded biological tissue implants of the present application are preferably made from allograft soft tissue sources and demineralized bone matrix. The present application provides biological implants exhibiting advantageous properties of absorption, expansion, resiliency and shape retention. The properties of the biological implants produced by the methods of the present application are leveraged in the creation and development of novel biological implant constructs and of novel methods of treatment and surgical technique.
    Type: Application
    Filed: March 12, 2013
    Publication date: January 2, 2014
    Inventors: Keith Cameron Koford, Nathaniel Scott Long, Erica Lee Scharringhausen, Randall Keith Hilliard
  • Publication number: 20140005794
    Abstract: The present invention relates to a granulated material mixture for regenerating bone, in particular by way of three-dimensional callus distraction, and to uses of said granulated material mixture. The granulated material mixture comprises rigid and deformable granulated materials.
    Type: Application
    Filed: March 10, 2012
    Publication date: January 2, 2014
    Applicant: CELGEN AG
    Inventor: Domonkos Horvath
  • Publication number: 20130304226
    Abstract: Methods for forming bone implants for the repair of the ends of bones at orthopedic joints, which implants have a Young's modulus close to that of human cortical bone. Substrates of dense isotropic graphite are coated overall with hard, microporous, isotropic pyrocarbon of specific character such that it can be polished to serve as an articular surface and can also securely receive an anchoring first metal layer through PVD. The first layer has a character such that, by thermal spraying a second biocompatible metal layer thereupon, fusion occurs and thereby anchors an outermost layer that is formed with a network of randomly interconnected pores and a surface character of peaks and valleys designed to promote enhanced appositional growth of cortical bone at the interface therewith.
    Type: Application
    Filed: February 19, 2013
    Publication date: November 14, 2013
    Applicant: ASCENSION ORTHOPEDICS, INC.
    Inventors: Joseph P. Ritz, Clive Scott
  • Publication number: 20130304227
    Abstract: An orthopaedic prosthesis is provided having a porous layer and a substrate. A method is also provided for fastening the porous layer to the substrate. The porous layer defines a plurality of through-holes therein to accommodate localized bonding of the porous layer to the substrate through each of the plurality of through-holes.
    Type: Application
    Filed: April 17, 2013
    Publication date: November 14, 2013
    Applicant: Zimmer, Inc.
    Inventor: Michael E. Hawkins
  • Publication number: 20130274890
    Abstract: A composite interbody bone implant device is provided including a body having a non-bone composition, such as a polymer, formed into a shape and including one or more cavities. An osteoinductive material, such as bone allograft tissue, may be retained in the one or more cavities of the body. The body is formable via injection molding and/or machining into a shape and size adapted for implantation at a surgical site. The dimensions of the body include a length, a width and a thickness, and the thickness of the body may be less than at least one of the length and width.
    Type: Application
    Filed: April 17, 2012
    Publication date: October 17, 2013
    Applicant: Warsaw Orthopedic, Inc.
    Inventor: William F. McKay
  • Publication number: 20130268085
    Abstract: Aspects of the present disclosure relate generally to preparing models of three-dimensional structures. In particular, a model of a three-dimensional structure constructed of porous geometries is prepared. A component file including a porous CAD volume having a boundary is prepared. A space including the porous CAD volume is populated with unit cells. The unit cells are populated with porous geometries having a plurality of struts having nodes on each end. The space is populated with at least one elongated fixation element extending beyond the boundary to produce an interlocking feature enabling assembly or engagement with a mating structure.
    Type: Application
    Filed: September 14, 2012
    Publication date: October 10, 2013
    Applicants: THE UNIVERSITY OF LIVERPOOL, Howmedica Osteonics Corp.
    Inventors: Nicholas Nai Guang Dong, Matthew P. Poggie, Robert W. Klein, Eric Jones, Christopher J. Sutcliffe, Joe Robinson, Dan Jones, Lewis Mullen, Robin Stamp
  • Publication number: 20130253657
    Abstract: The production method of an implant material of the present invention includes step (A): a step of setting a porous ceramic material having substantially unidirectionally arrayed pores at any depth position inside a container, step (B): a step of filling the container with a cell-containing liquid containing at least bone marrow blood and/or peripheral blood, and step (C): a step of applying, on the container, a centrifugal force in the direction along the axis of the container.
    Type: Application
    Filed: November 10, 2011
    Publication date: September 26, 2013
    Applicants: University of Tsukuba, KURARAY CO., LTD.
    Inventors: Yuji Hotta, Masataka Sakane
  • Publication number: 20130231750
    Abstract: A prosthesis comprising: an inner layer (4) formed from a polyaryletherketone; a first outer layer (2a) adjacent to said inner layer formed from a porous polyaryletherketone, at least some of said pores having located therein material to promote osteointegration; and a second outer layer (2b) adjacent to said first outer layer formed from a porous polyaryletherketone, a portion of said pores being free of material to promote osteointegration. The invention also relates to a method of manufacture of the prosthesis.
    Type: Application
    Filed: February 3, 2011
    Publication date: September 5, 2013
    Applicant: FINSBURY (DEVELOPMENT) LIMITED
    Inventor: Andrew Clive Taylor
  • Patent number: 8524798
    Abstract: Compositions for use in treating and repairing orthopedic defects are provided. The compositions are especially useful for performing percutaneous vertebroplasty, percutaneous kyphoplasty and other procedures. When cured, the compositions are relatively solid but compressible, and prior to curing are viscous liquids with a low enough viscosity to fill voids in cavities such as voids within fractured vertebrae. Optionally, the properties of a composition according to the invention can be adjusted taking into account the hardness and density of the orthopedic structure to be repaired. Also disclosed are devices and methods for using the compositions, and a kit containing components for forming and utilizing the composition.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: September 3, 2013
    Inventors: Linda M. Trebing, Ralph W. Carmichael
  • Publication number: 20130218288
    Abstract: A dynamic porous coating for an orthopedic implant, wherein the dynamic porous coating is adapted to apply an expansive force against adjacent bone so as to fill gaps between the dynamic porous coating and adjacent bone and to create an interference fit between the orthopedic implant and the adjacent bone.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 22, 2013
    Inventor: MX ORTHOPEDICS, CORP.
  • Publication number: 20130211536
    Abstract: A bone augment for repairing a bone defect and associated method. The bone augment includes a porous body and a reinforcement member. The porous body defines a plurality of pores and is configured to be intraoperatively shaped to correspond to the bone defect.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 15, 2013
    Applicant: Biomet Manufacturing Corporation
    Inventor: Biomet Manufacturing Corporation
  • Patent number: 8486436
    Abstract: Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: July 16, 2013
    Assignee: Georgia Tech Research Corporation
    Inventors: Barbara D. Boyan, Stephen J. Kennedy, Zvi Schwartz