Chemical Patents (Class 703/12)
  • Patent number: 10216707
    Abstract: Disclosed are methods and systems for performing uncertainty calculations. For example, a numeric value and an error range associated with the numeric value are converted by a processor into a trans-imaginary input dual which is a hybrid of numeric and geometric information having real and complex numbers. A dual calculation is performed using the trans-imaginary input dual to produce a trans-imaginary output dual, and the processor then converts the trans-imaginary output dual to a real number output numeric value that includes both a real number and real number error range or uncertainty associated with that real number.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: February 26, 2019
    Assignee: Clarkson University
    Inventor: Ronald S. LaFleur
  • Patent number: 10147300
    Abstract: A set of sensors is disposed beside a cylinder to collect a first set of temperature points. The first set of temperature points is updated and distributed on a coordinate plane corresponding to a length and rotation degrees of the cylinder. The coordinate plane is segmented along a horizontal axis with a fixed length to define a rectangular area, and a second set of temperature points is distributed on the rectangular area. The second set of temperature points is a subset of the first set of temperature points. On the rectangular area, the second set of temperature points is clustered into n sets of temperature points using a k means algorithm. A notification signal is sent according to an xth set of temperature points of the n sets of temperature points. The xth set of temperature points has a highest mean temperature among the n sets of temperature points.
    Type: Grant
    Filed: May 6, 2018
    Date of Patent: December 4, 2018
    Assignee: TCC INFORMATION SYSTEMS CORP.
    Inventors: Chien-Chih Chang, Yuan-Chen Chang, Ko-Yun Lee
  • Patent number: 10049172
    Abstract: Changes in capillary pressure and relative permeabilities in reactive transport codes or reservoir simulators are formed by computer modeling. Based on continuum-scale hydraulic properties, the pore size distribution (PSD) is determined from a capillary pressure curve using the capillary tube concept. Changes in mineral volume through equilibrium or kinetic mineral reactions are then translated to changes in pore radii of the pore size distribution by selectively changing the radii of water occupied pores. The resulting new pore size distribution is converted back to an updated capillary pressure curve, which is then used for determining and forming models of total permeability and relative permeabilities at the continuum scale.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: August 14, 2018
    Assignee: Saudi Arabian Oil Company
    Inventors: Shuo Zhang, Huihai Liu
  • Patent number: 10013514
    Abstract: A granular material is a simulation target, wherein a force acting on each grain is expressed by a potential dependent term and an energy dissipation term. The potential dependent term depends on an interaction potential ? between the grains. Physical quantities included in the potential dependent term are renormalization-transformed so that a hamiltonian form expressed by a kinetic energy of the each grain and a potential energy based on the interaction potential ? does not change. Physical quantities included in the dissipation term are renormalization-transformed so that a change rate of the potential dependent term and a change rate of the dissipation term become equal. Temporal development of a renormalized granular material is calculated by performing numerical integration with respect to a motion equation of each grain of the renormalized granular material.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: July 3, 2018
    Assignee: SUMITOMO HEAVY INDUSTRIES, LTD.
    Inventors: Ryouta Hirose, Daiji Ichishima
  • Patent number: 10012764
    Abstract: A computer-implemented method for determining an amount of hydrocarbon fluid present in a rock of a hydrocarbon-producing reservoir is provided. The rock comprises organic matter and porous and permeable inorganic matter. The method comprises the steps of receiving data relating to chemical and kinetic properties of the organic matter, rock lithology data, rock thickness and reservoir temperature and pressure data, inputting the received data into a computer-implemented model, and operating the model. The model operates to a) simulate hydrocarbon fluid generation in the rock based on the input data and thereby determine an amount of generated hydrocarbon fluid, b) generate predicted data, and c) determine a total amount of hydrocarbon fluid present in the rock based on the predicted data.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: July 3, 2018
    Assignee: BP EXPLORATION OPERATING COMPANY LIMITED
    Inventors: Tony Barwise, Mark James Osborne
  • Patent number: 10002432
    Abstract: Provided is a method and apparatus for rendering a target fluid that include defining level-set information of fluid particles configuring a modeled target fluid. The level-set information comprises a shortest distance from a surface of the target fluid to the fluid particles. The method and apparatus are include discarding internal particles of the target fluid from the modeled target fluid based on the level-set information of the fluid particles, and calculating thickness information of the target fluid, from which the internal particles are discarded, based on depth information on the fluid particles. The target fluid is rendered based on the thickness information of the target fluid.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: June 19, 2018
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hwiryong Jung, Nahyup Kang, Jiyeon Kim, Donghoon Sagong, Hyong Euk Lee
  • Patent number: 9858529
    Abstract: Techniques for use in connection with performing optimization using a plurality of objective functions associated with a respective plurality of tasks. The techniques include using at least one computer hardware processor to perform: identifying, based at least in part on a joint probabilistic model of the plurality of objective functions, a first point at which to evaluate an objective function in the plurality of objective functions; selecting, based at least in part on the joint probabilistic model, a first objective function in the plurality of objective functions to evaluate at the identified first point; evaluating the first objective function at the identified first point; and updating the joint probabilistic model based on results of the evaluation to obtain an updated joint probabilistic model.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: January 2, 2018
    Assignees: President and Fellows of Harvard College, The Governing Council of the Univ. of Toronto
    Inventors: Ryan P. Adams, Roland Jasper Snoek, Kevin Swersky
  • Patent number: 9824192
    Abstract: A computer simulation method for a macromolecular material and filler is disclosed, wherein a polymer model of a macromolecular chain of the macromolecular material and a filler model of the filler are defined; and a molecular dynamics calculation is performed using the filler model and the polymer models disposed in a space in order to compute the thickness of an interface layer between the filler and the macromolecular material. To compute the thickness, the space is partitioned into domains bounded by boundary surfaces; relaxation moduli of the domains are computed; and based on a variation of the relaxation moduli of the domains, the thickness of the interface layer is computed.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: November 21, 2017
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventor: Shinichi Ueno
  • Patent number: 9679116
    Abstract: A processor based method for measuring dimensional properties of a photoresist profile by determining a number acid generators and quenchers within a photoresist volume, determining a number of photons absorbed by the photoresist volume, determining a number of the acid generators converted to acid, determining a number of acid and quencher reactions within the photoresist volume, calculating a development of the photoresist volume, producing with the processor a three-dimensional simulated scanning electron microscope image of the photoresist profile created by the development of the photoresist volume, and measuring the dimensional properties of the photoresist profile.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: June 13, 2017
    Assignee: KLA-Tencor Corporation
    Inventors: John J. Biafore, Mark D. Smith, John S. Graves, III, David Blankenship
  • Patent number: 9552462
    Abstract: A method for predicting petroleum expulsion. A chemical structure of a kerogen is defined and a plurality of reaction products of the kerogen under geologic heating rates are identified. The plurality of reaction products are grouped into a plurality of product lumps based on their chemical composition and predicting petroleum expulsion for each of the plurality of product lumps based on secondary cracking reactions.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: January 24, 2017
    Assignee: ExxonMobil Upstream Research Company
    Inventors: Clifford C. Walters, Howard J. Freund, Simon R. Kelemen, Paul J. Hicks, Jr.
  • Patent number: 9465519
    Abstract: Embodiments describe a non-transitory computer-readable storage medium encoded with instructions, executable by a processor, comprising instructions for a method for performing a biological workflow in silico comprising: presenting to a user a plurality of subroutines listed in a sequential order of the workflow, wherein at least two subroutines comprise two steps; providing the user ability to navigate to any subroutine and/or step, to select a subroutine, to view, set, or change one or more parameters associated with step/subroutine; providing option to display biomolecule(s) resulting from execution of the subroutines/steps; and providing an option to navigate to a prior subroutine and change a parameter of a step of the prior subroutine and execute the step of the prior subroutine, if the user is not satisfied with the displayed biomolecule(s). Computer systems and methods for performing a biological workflow in silico are also described.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: October 11, 2016
    Inventors: Maurice Ling, Kok Hien Gan, Kevin Clancy, Raymond Tecotzky, Kin Chong Sam
  • Patent number: 9418186
    Abstract: Partition coefficients for solutes in solvent-water systems are estimated based on corresponding values for the octanol-water system. The estimation of the partition coefficient includes correction factors based on the nature of the solute and the solvent. Petroleum fractions are an example of a suitable solvent for which a partition coefficient can be estimated, although other types of solvents can be used in developing a model for use in the estimation.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: August 16, 2016
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Narasimhan Sundaram, Bryan M Knickerbocker, Steven Wong
  • Patent number: 9234800
    Abstract: A spectrometer recognizes a measurement target on the basis of the spectral data set of observed light detected by a spectral sensor capable of measuring wavelength information and light intensity information. The spectrometer is provided with a spectral data processor. Spectral data sets are detected at two different positions by the spectral sensor, and the processor subtracts a first spectral data set from a second spectral data set, or divides the first spectral data set by the second spectral data set to calculate one phase correlation spectral data set, which is correlated to the spectral data sets at the two different positions. The processor simultaneously identifies the measurement target corresponding to the two different positions on the basis of the correlation spectral data set.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: January 12, 2016
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NEC CORPORATION
    Inventors: Shinya Kawamata, Ryuji Funayama, Tsutomu Ishi, Yumiko Yoshikawa
  • Patent number: 9213030
    Abstract: We describe a method of generating a classification model capable of distinguishing between two biological states, the method comprising the steps of: (a) providing a training dataset, X, comprising concentrations of a plurality of lipids in a biological sample in a first state and a biological sample in a second state; (b) subjecting the training dataset X to Principal Components Analysis (PCA), in which the PCA analysis generates a transformation matrix, C, and a transformed dataset, Yl; (c) subjecting the transformed dataset Yl to Support Vector Machines (SVM) analysis, in which the SVM analysis generates a SVM model, S; (d) forming a classification model comprising (i) the transformation matrix C, and (ii) the corresponding SVM model S.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: December 15, 2015
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Markus R. Wenk, Gek Huey Chua, Aaron Zefrin Fernandis, Xueli Guan
  • Patent number: 9174193
    Abstract: Tubular reactor for use in polymerization reactions having a design pressure PR of 40-65 barg. The reactor includes a tube with a wall, and at least a portion of the tube is oriented vertically, with at least part of the vertical portion being surrounded by a concentric jacket for the passage of cooling fluid. The design pressure in barg of the jacket PJ is less than 0.0018·PR2.25.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: November 3, 2015
    Assignee: INEOS MANUFACTURING BELGIUM
    Inventors: Marc Parisel, Brent Walworth
  • Patent number: 9170572
    Abstract: A method of dynamic model selection for hybrid linear/non-linear process control includes developing a plurality of process models including at least one linear process model and at least one non-linear process model from inputs including dynamic process data from a processing system that runs a physical process. At least two of the plurality of process models are selected based on a performance comparison based on at least one metric, wherein the selected process models number less than a number of the plurality of process models received. A multi-model controller is generated that includes the selected process models. The physical process is simulated using the multi-model controller by applying the selected process models to obtain closed loop performance test data for each of the selected models. The performance test data is compared. A selected process model is then selected.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: October 27, 2015
    Assignee: Honeywell International Inc.
    Inventors: Ward MacArthur, Sriram Hallihole, Ranganathan Srinivasan, Madhukar Madhavamurthy Gundappa, Mandar Subhash Vartak, Gobinath Pandurangan, S. Chandrakanth Vittal, Lucy Ning Liu, Sanjay Kantilal Dave, Avijit Das, Sreesathya Sathyabhama Sreekantan, Roshan Yohannan, Rajni Jain
  • Patent number: 9147012
    Abstract: A content recommendation method and system including providing a plurality of content items, the number of items designated as N, representing each of the N content items symbolically represented as a unique point on a two-dimensional plane, thereby associating an x and y coordinate with each one of the content items, changing the x and y coordinate of the unique point based on user requests for other content items besides the one of the N content items, determining a distance between the unique point and a multiplicity of points corresponding to a multiplicity of other content items, returning at least a first content recommendation to a user, the at least a first content recommendation including a content item associated with a point closer than any other point to a point associated with the content item presently being viewed by the user. Related methods and apparatus are also described.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: September 29, 2015
    Assignee: Cisco Technology Inc.
    Inventor: Nicolas Gaude
  • Patent number: 9141911
    Abstract: A computer-based apparatus and method for automated data screening and selection in model identification and model adaptation in multivariable process control is disclosed. Data sample status information, PID control loop associations and internally built MISO (Multi-input, Single-output) predictive models are employed to automatically screen individual time-series of data, and based on various criteria bad data is automatically identified and marked for removal. The resulting plant step test/operational data is also repaired by interpolated replacement values substituted for certain removed bad data that satisfy some conditions. Computer implemented data point interconnection and adjustment techniques are provided to guarantee smooth/continuous replacement values.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: September 22, 2015
    Assignee: Aspen Technology, Inc.
    Inventors: Hong Zhao, Magiel J. Harmse
  • Publication number: 20150148514
    Abstract: A system and method for producing a bioabsorbable thermoplastic polyurethane tailored to a medical application are provided. The method includes identifying suitable thermoplastic polyurethane properties based on the medical application. The thermoplastic polyurethane comprises units derived from a diol chain extender, a diisocyanate, and a polyol. The thermoplastic polyurethane properties include a biodegradation rate and at least one physical property. The method includes identifying a base thermoplastic polyurethane and altering at least one parameter of the base thermoplastic polyurethane which relates to the desired thermoplastic polyurethane properties to generate a candidate thermoplastic polyurethane. The altering may be performed iteratively until the suitable range of thermoplastic polyurethane properties based on the medical application is met.
    Type: Application
    Filed: June 24, 2013
    Publication date: May 28, 2015
    Inventors: Umit G. Makal, Roger W. Day
  • Patent number: 9043160
    Abstract: The invention is directed to methods for determining clonotypes and clonotype profiles in assays for analyzing immune repertoires by high throughput nucleic acid sequencing of somatically recombined immune molecules. In one aspect, the invention comprises generating a clonotype profile from an individual by generating sequence reads from a sample of recombined immune molecules; forming from the sequence reads a sequence tree representing candidate clonotypes each having a frequency; coalescing with a highest frequency candidate clonotype any lesser frequency candidate clonotypes whenever such lesser frequency is below a predetermined value and whenever a sequence difference therebetween is below a predetermined value to form a clonotype. After such coalescence, the candidate clonotypes is removed from the sequence tree and the process is repeated.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: May 26, 2015
    Assignee: SEQUENTA, INC.
    Inventors: Martin Moorhead, Malek Faham, Thomas Willis
  • Patent number: 9043157
    Abstract: A device for the collection and processing of information relating to the exposure of one or more persons to one or more products of chemical or biological origin has: at least one coded sensor for automatic or semi-automatic identification of a person likely to be exposed to at least one product, at least one coded sensor for the collection of information relating to the handling of at least one product by the person likely to be exposed to the product, at least one sensor for validating the information collected by the identification and collection sensors, at least one module for reading at least one coded sensor, and a module for processing information collected by the sensors.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: May 26, 2015
    Assignee: BIOGEMMA
    Inventors: Didier Hatsch, Pascual Perez
  • Patent number: 9037445
    Abstract: Methods are provided herein for: calculating cell growth rates in various environments and genetic backgrounds; calculating the order of substrate utilization from a defined growth medium; calculating metabolic flux reorganization in various environments and at various growth rates; and calculating the maximum metabolic rate and optimal metabolite concentrations and enzyme activities by applying a computational optimization method to a kinetic model of a metabolic pathway. The optimization methods use intracellular molecular crowding parameters and/or well as kinetic rates to assist in modeling metabolic activity.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: May 19, 2015
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Zoltan N. Oltvai, Alexei Vazquez
  • Patent number: 9026421
    Abstract: A method for predicting onset of liquid phase to solid phase transition of a mixture including a plurality of fatty acid methyl esters components. The method includes identifying chemical and molecular structure of each component of the mixture, calculating activity coefficients for each component in a liquid phase and a solid phase, calculating chemical potential for each component in the liquid phase and in the solid phase at a predetermined temperature and a predetermined pressure, and calculating the cloud point of the mixture. A system for carrying out the method is also disclosed.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: May 5, 2015
    Assignee: Purdue Research Foundation
    Inventors: Bernard Y Tao, Junli Liu
  • Patent number: 9012368
    Abstract: A system and method for systematically generating potential metal-organic framework (MOFs) structures given an input library of building blocks is provided herein. One or more material properties of the potential MOFs are evaluated using computational simulations. A range of material properties (surface area, pore volume, pore size distribution, powder x-ray diffraction pattern, methane adsorption capability, and the like) can be estimated, and in doing so, illuminate unidentified structure-property relationships that may only have been recognized by taking a global view of MOF structures. In addition to identifying structure-property relationships, this systematic approach to identify the MOFs of interest is used to identify one or more MOFs that may be useful for high pressure methane storage.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 21, 2015
    Assignee: Northwestern University
    Inventors: Christopher E. Wilmer, Michael Leaf, Randall Q. Snurr, Omar K. Farha, Joseph T. Hupp
  • Patent number: 9008807
    Abstract: This invention provides a system and method of Advanced Process Control for optimal operation of multi-unit plants in large scale processing and power generation industries. The invention framework includes the following components: continuous real time dynamic process simulation, automatic coefficient adjustment of dynamic and static process models, automatic construction of transfer functions, determination of globally optimal operating point specific to current conditions, provision of additional optimal operating scenarios through a variety of unit combinations, and calculation of operational forecasts in accordance with planned production.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: April 14, 2015
    Assignee: Statistics & Control, Inc.
    Inventors: Vadim Shapiro, Ilya Markevich, Dmitriy Khots
  • Patent number: 9002655
    Abstract: A medical apparatus for extracorporeal blood treatment and a method for determining blood parameter value have been provided. The medical apparatus has a control unit (9) configured for taking from a storage memory (10) a plurality of blood parameter value measures each made through the sensors (8) provided on the bloodline set of each of a machines plurality at different patient treatment sessions; all the blood parameter values relate to the same patient; receiving at least a corresponding laboratory measured value of the same blood parameter relating to the same patient and a laboratory measurement time; determining a correction factor function of a difference between a measured value made though the sensor and a laboratory measured value; obtaining an actual value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: April 7, 2015
    Assignee: Gambro Lundia AB
    Inventor: Bernard Bene
  • Patent number: 9002654
    Abstract: The present invention relates to methods of measuring biomarkers to determine the probability of a periodontal and/or peri-implant disease. More specifically, the invention provides a panel of biomarkers that, when used in combination, can allow determination of the probability of a periodontal and/or peri-implant disease state with extremely high accuracy.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: April 7, 2015
    Assignees: The Regents of the University of Michigan, Sandia National Laboratories
    Inventors: Thomas Braun, William V. Giannobile, Amy E. Herr, Anup K. Singh, Charlie Shelburne
  • Patent number: 8977504
    Abstract: Apparatus for monitoring a substance in human or animal in real time, the apparatus comprising a sensor providing a time series of measurements of substance level, said measurements being indicative of an inferred level of said substance in a part of said human or animal and a processor which applies an interacting multiple model strategy to a system model to provide a combined estimate of the inferred substance level from the substance level measurements. The substance may be glucose. The apparatus may also be adapted to control said substance using said interacting multiple model strategy to a system model to provide a combined estimate of a dose to be applied.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: March 10, 2015
    Assignee: Cambridge Enterprise Limited
    Inventor: Roman Hovorka
  • Patent number: 8977506
    Abstract: A computer having a memory stores instructions for receiving data. The data comprises one or more characteristics for each cellular constituent in a plurality of cellular constituents that have been measured in a test organism of a species or a test biological specimen from an organism of the species. The memory further stores instructions for computing a model in a plurality of models, wherein the model is characterized by a model score that represents the likelihood of a biological feature in the test organism or the test biological specimen. Computation of the model comprises determining the model score using one or more characteristics for one or more cellular constituents in the plurality of cellular constituents. The memory also stores instructions for repeating the instructions for computing one or more times, thereby computing the plurality of models. The memory also stores instructions for communicating computed model scores.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: March 10, 2015
    Assignee: Response Genetics, Inc.
    Inventor: Glenda G. Anderson
  • Patent number: 8965707
    Abstract: An apparatus and method for generating a prescription form is disclosed. The method includes displaying a first menu containing a plurality of therapy menu items. The method also includes displaying a second menu containing at least one qualifier menu item. The method further includes displaying a third menu containing at least one drug menu item. The method includes, upon selection of a therapy menu item, a qualifier menu item, and a drug menu item, selecting a protocol including one or more patient specific pump parameters corresponding to the therapy menu item, the qualifier menu item, and the drug menu item. The method also includes displaying a prescription form including at least one of the one or more patient specific pump parameters.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: February 24, 2015
    Assignee: Smiths Medical ASD, Inc.
    Inventor: Michael L. Blomquist
  • Publication number: 20150051882
    Abstract: An apparatus is provided for causing a behavioral response in an insect species. The apparatus may include a housing, a radiating emitter, a directing apparatus, and a power source coupled to the radiating emitter. The radiating emitter may be configured to emit radiation at one or more wavelengths simulating an emission spectrum of a chemical compound of interest that may cause a behavioral response in the insect species. The directing apparatus disposed within the housing may be configured to control a direction of the emitted radiation and the power source may be configured to control an intensity of the emitted radiation.
    Type: Application
    Filed: August 29, 2013
    Publication date: February 19, 2015
    Applicant: TECHNOLOGY S.G., LP
    Inventors: Eric L. CANFIELD, Robert P. ALSTON, Thomas M. DYKSTRA
  • Patent number: 8958991
    Abstract: Described and illustrated herein is an exemplary method of operating an analyte measurement device having a display, user interface, processor, memory, and user interface buttons. Such method can be achieved by measuring an analyte with the analyte measurement device, displaying a value representative of the analyte, querying a user to select a predetermined flag to associate the predetermined flag with the value, and pressing only one of the user interface buttons once to store the predetermined flag with the value in the memory of the analyte measurement device. In one embodiment, the testing device is a glucose meter and the analyte being tested is glucose.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: February 17, 2015
    Assignee: LifeScan Scotland Limited
    Inventors: Chris Stephens, Lynne Coventry, Raymond John Welsh, David Angus Sturrock, Alexander Strachan, Mel Chiba, Allan Orr
  • Patent number: 8958990
    Abstract: A sample analyzer comprising: a measurement section for measuring a sample of an animal; a memory for storing a measurement data by the measurement section; an analysis section for analyzing the measurement data stored on the memory in accordance with a first analysis condition corresponding to a previous setting of a species of an animal; and a selection receiver for receiving a selection of a species of an animal, which is different from the species of the previous setting, after analyzing the measurement data by the analysis section; wherein the analysis section analyzes the measurement data stored on the memory in accordance with a second analysis condition corresponding to the selection of a species of an animal when the selection receiver receives the selection of a species of an animal, is disclosed. A sample analyzing method is also disclosed.
    Type: Grant
    Filed: October 3, 2006
    Date of Patent: February 17, 2015
    Assignee: Sysmex Corporation
    Inventor: Hideki Hirayama
  • Patent number: 8959006
    Abstract: A system for conducting a real-time power capacity assessment of an electrical system is disclosed. The system includes a data acquisition component, a power analytics server and a client terminal. The data acquisition component is communicatively connected to a sensor configured to acquire real-time data output from the electrical system. The power analytics server is communicatively connected to the data acquisition component and is comprised of a virtual system modeling engine, an analytics engine and a machine learning engine. The machine learning engine is configured to store and process patterns observed from the real-time data output and the predicted data output, forecasting power capacity of the electrical system subjected to a simulated contingency event.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: February 17, 2015
    Assignee: Power Analytics Corporation
    Inventor: Adib Nasle
  • Patent number: 8949036
    Abstract: The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a sample of DNA from the mother of the fetus and from the fetus, and from genotypic data from the mother and optionally also from the father. The ploidy state is determined by using a joint distribution model to create a set of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. In an embodiment, the mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: February 3, 2015
    Assignee: Natera, Inc.
    Inventors: Matthew Rabinowitz, George Gemelos, Milena Banjevic, Allison Ryan, Zachary Demko, Matthew Hill, Bernhard Zimmermann, Johan Baner
  • Patent number: 8942926
    Abstract: A method for diagnosing a disease or pathological condition in a non-human animal. An ion mobility spectrometry measurement (IMS) or a differential mobility spectrometry (DMS) is carried out on a body sample from the animal to determine an amount of ions formed by at least two biogenic amines contained in the sample. A ratio is calculated of the amounts of ions formed by the different biogenic amines in the sample, wherein the ratio is indicative of the presence or absence of the disease or pathological condition.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: January 27, 2015
    Assignee: Q-Scent Ltd.
    Inventors: Zeev Karpas, Shmuel Marcus, Moshe Golan
  • Publication number: 20150025871
    Abstract: A computerized procedure for aligning molecules for use in CoMFA or other 3D QSAR methodologies does not rely on fragmentation of the molecules instead, aligning molecules based upon comparison to identified template molecules. Initially an anchor bond is identified in the candidate and template molecule that have similar atoms at each end of the bonds. Unlike prior art methods, the anchor bond need not be an acyclic bond. The candidate molecule is overlaid onto the template molecule by aligning the anchor bonds. Starting and working away from the anchor bond, matching atoms or atom types between the candidate and template molecule are identified. Multiple layers of atomic connections are evaluated for matches. The atoms may or may not be contained within ring structures. Once all matching atoms have been identified, the 3D coordinates of the template atoms are assigned to the corresponding atoms in the candidate molecule to place the candidate molecule into alignment.
    Type: Application
    Filed: July 22, 2014
    Publication date: January 22, 2015
    Inventor: Richard D. Cramer
  • Patent number: 8924160
    Abstract: A health-monitoring device assesses the health of a user based on levels of two analytes in a biological fluid. A first analyte that is utilized to assess a user's health is a fat metabolism analyte, such as ketones, free fatty acids and glycerol, which is indicative of fat metabolism. A second analyte that is utilized is a glucose metabolism analyte, such as glucose. The levels of the two analytes may be used to assess insulin sensitivity, to detect both recent hypoglycemia and the cause of high glucose levels, and/or to guide therapeutic intervention. The dual analyte model may calculate a discrepancy between an actual insulin activity level and a theoretical insulin activity level. The dual analyte model of the present invention may be used to identify individuals at risk for metabolic syndrome, insulin resistance and non-insulin dependent diabetes, and allows monitoring of the progression of those disease states, as well as progress made by therapeutic interventions.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: December 30, 2014
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Piet Moerman
  • Patent number: 8924159
    Abstract: Methods and system to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: December 30, 2014
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Marc Barry Taub, Timothy Christian Dunn, Nathan Christopher Crouther
  • Patent number: 8924161
    Abstract: A health-monitoring device assesses the health of a user based on levels of two analytes in a biological fluid. A first analyte that is utilized to assess a user's health is a fat metabolism analyte, such as ketones, free fatty acids and glycerol, which is indicative of fat metabolism. A second analyte that is utilized is a glucose metabolism analyte, such as glucose. The levels of the two analytes may be used to assess insulin sensitivity, to detect both recent hypoglycemia and the cause of high glucose levels, and/or to guide therapeutic intervention. The dual analyte model may calculate a discrepancy between an actual insulin activity level and a theoretical insulin activity level. The dual analyte model of the present invention may be used to identify individuals at risk for metabolic syndrome, insulin resistance and non-insulin dependent diabetes, and allows monitoring of the progression of those disease states, as well as progress made by therapeutic interventions.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: December 30, 2014
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Piet Moerman
  • Publication number: 20140365195
    Abstract: A system for monitoring a process determined by a set of process data in a multidimensional process data domain pertaining to process input-output data, the system comprising: means for acquiring a plurality of historic process data sets; means for obtaining a transformation from the multidimensional process data domain to a model data domain of lower dimension by performing multivariate data analysis; and means for transforming a current process data set to a model data set to monitor the process.
    Type: Application
    Filed: June 5, 2014
    Publication date: December 11, 2014
    Applicant: SCIENTIFIC DESIGN COMPANY, INC.
    Inventors: Sandip K. Lahiri, Mansoor Husain
  • Publication number: 20140343914
    Abstract: Systems and methods for creating a model of composition for a current composite created by combining a plurality of hydrocarbon streams. The method comprises receiving at least one primary data value related to the current composite, associating the at least one primary data value with a profile of the current composite, selecting a modeling scenario for the current composite using a hierarchy of modeling scenarios, and creating a model of composition for the current composite using at least one processor, The modeling scenario is selected based at least in part on a collection of primary data values associated with the profile of the current composite. The model of composition is created based at least in part on the modeling scenario and the collection of primary data values associated with the profile of the current composite. Systems of creating the model of composition are also disclosed.
    Type: Application
    Filed: May 16, 2013
    Publication date: November 20, 2014
    Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Anantha SUNDARAM, Liang J CHANG, Dilip BHATTACHARYYA, Matthew NAYSMITH, David A JOE, Keith MEDCALF, David S SCHULTZ
  • Patent number: 8874420
    Abstract: Methods for method for increasing genetic gain in a breeding process are provided. Also provided are methods for choosing breeding pairs predicted to produce progeny having desired phenotypes, methods for increasing the likelihood of producing progeny individual having desired phenotypes, methods for generating progeny individual having desired genotypes and/or phenotypes, progeny produced thereby, and cells, seeds, parts, and tissues cultures thereof.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: October 28, 2014
    Assignee: Syngenta Participations AG
    Inventors: Zhigang Guo, Venkata Krishna Kishore
  • Publication number: 20140309974
    Abstract: A method of combinatorial optimization includes: (1) defining an objective function to optimize a combination of N input parameters of a complex system, wherein the objective function includes a weighted sum of n different optimization criteria, N?2, and n?2; (2) applying an initial combination of the N input parameters to the complex system to yield an initial output response; (3) executing an optimization procedure to generate an updated combination of the N input parameters, wherein executing the optimization procedure includes calculating an initial value of the objective function based on at least one of (a) the initial combination of the N input parameters and (b) the initial output response; and (4) applying the updated combination of the N input parameters to the complex system to yield an updated output response.
    Type: Application
    Filed: April 15, 2014
    Publication date: October 16, 2014
    Inventors: Chih-Ming HO, Xianting DING, Genhong CHENG, David J. SANCHEZ
  • Patent number: 8862438
    Abstract: A method for improving the prediction of polymer properties and a system having improved polymer property prediction capabilities is provided. The method for improving the prediction of polymer properties comprises: (1) providing a polymer; (2) providing a prediction model; (3) utilizing said prediction model to define an average polymer property prediction value; (4) determining a feasible range; (5) measuring one or more properties of said polymer; (6) determining whether said one or measured polymer properties are within said feasible range: (7) validating said one or more measured polymer properties if said one or more measured polymer properties fall within the feasible range or invalidating said one or more measured polymer properties if said one or more measured polymer properties fall outside of the feasible range; (8) optionally updating said prediction model; (9) repeating said previous steps at least one or more times; and (10) thereby improving the prediction of polymer properties.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: October 14, 2014
    Assignee: Dow Global Technologies LLC
    Inventors: Jeffrey B. Drabish, John R. Parrish, Marcel Schaefer, Ivan J. Hartley, Paul K. Samples, Mark L. Nelson
  • Patent number: 8862410
    Abstract: The compositions and methods provided herein allow for identification of causative genetic biomarkers for a disease condition or drug response.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: October 14, 2014
    Assignee: Population Diagnostics, Inc.
    Inventors: Eli Hatchwell, Peggy S. Eis
  • Patent number: 8855940
    Abstract: The present invention relates to a method of detecting coliform bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of data relating to that method.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: October 7, 2014
    Assignee: Bowling Green State University
    Inventor: Robert K. Vincent
  • Patent number: 8855937
    Abstract: A system for estimating a crop characteristic comprises a database, a plant growth model correlator, and a crop characteristic estimator. The database includes plant growth models for a plurality of fields. The plant growth model correlator is communicatively coupled with the database. The plant growth model correlator is configured for determining at least one harvested field with a first plant growth model which correlates with a second plant growth model for at least a portion of an unharvested field. The crop characteristic estimator is configured for estimating a crop characteristic for the unharvested field based on actual crop characteristic data obtained from the at least one harvested field.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: October 7, 2014
    Assignee: Trimble Navigation Limited
    Inventor: Robert J. Lindores
  • Patent number: 8843321
    Abstract: Methods and systems are disclosed for estimating a glucose level of a person having diabetes comprises. One method may comprise: receiving into a computing device a plurality of measured glucose results from a glucose sensor coupled to the person; using the computing device to analyze the plurality of measured glucose results with a probability analysis tool configured to determine a probability of glucose sensor accuracy based on the plurality of measured glucose results; and using the computing device to estimate a glucose level of the person with a recursive filter configured to estimate the glucose level based on the plurality of measured glucose results weighted with the probability of glucose sensor accuracy.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: September 23, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: David L. Duke, Abhishek S. Soni, Stefan Weinert
  • Publication number: 20140274751
    Abstract: Provided herein is technology relating to identifying unknown compounds and particularly, but not exclusively, to methods and systems for identifying unknown compounds by gas chromatography-mass spectrometry by use of retention index as a second dimension for identification.
    Type: Application
    Filed: August 3, 2012
    Publication date: September 18, 2014
    Applicant: SMITHS DETECTION INC.
    Inventors: Charles Sadowski, Greger Andersson, Kevin Judge