The Polynucleotide Confers Pathogen Or Pest Resistance Patents (Class 800/279)
  • Patent number: 11365421
    Abstract: Provided are isolated polynucleotides comprising a nucleic acid sequence encoding a polypeptide at least 80% identical to SEQ ID NO: 422, 362-421, 423-601, 2429-4085 and 4086, such as a polynucleotide which is at least 80% identical to SEQ ID NO: 260, 1-259, 261-361, 602-2427 and 2428, nucleic acid constructs comprising same, plant cells comprising same, transgenic plants expressing same, and methods of generating thereof for increasing the yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, nitrogen use efficiency and/or abiotic stress tolerance of a plant.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: June 21, 2022
    Assignee: Evogene Ltd.
    Inventors: Noa Matarasso, Hagai Karchi
  • Patent number: 11365423
    Abstract: Disclosed is a method for obtaining multileaflet Medicago sativa materials by means of MsPALM1 artificial site-directed mutants. The method comprises: selecting a target site from an exon region of a compound leaf developmental regulatory gene MsPALM1 of Medicago sativa and constructing a plant CRISPR/Cas9 editing recombinant vector MsCRISPR/Cas9::PALM1 and introducing the vector into Medicago sativa cells and regenerating into plants, cutting and repairing to cause a loss-of-function mutation in the MsPALM1 gene of Medicago sativa cells, and then screening the mutant plants by restriction endonuclease digestion and/or targeted deep sequencing of the target sites of the regenerated plants to obtain lines carrying four MsPALM1 allelic genes with simultaneous loss of function mutation. After phenotypic identification, it was confirmed that the compound leaves of the regenerated plants changed from three leaflets to five leaflets.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: June 21, 2022
    Assignee: GUANGDONG SANJIE FORAGE BIOTECHNOLOGY CO., LTD
    Inventors: Haitao Chen, Wen Wang, Xiongping Xie, Qiang Qiu, Zhanhuan Shang, Kexian Su, Hui He
  • Patent number: 11286495
    Abstract: Provided are methods of increasing nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence at least 80% identical to SEQ ID NO:1-467, 785-3047; or an exogenous polynucleotide encoding a polypeptide at least 80% identical to SEQ ID NO:468-784, 3048-4333, 4335-4682. Also provided isolated polynucleotide comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOs:1-467, 785-3047, which can be used to increase nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: March 29, 2022
    Assignee: Evogene Ltd.
    Inventors: Basia Judith Vinocur, Alex Diber, Hagai Karchi
  • Patent number: 11254950
    Abstract: Nucleotide sequences are disclosed encoding novel, insecticidal TIC4747 and related proteins exhibiting Hemipteran and Lepidopteran inhibitory activity, as well as fragments thereof. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing a polynucleotide construct encoding one or more of the toxin proteins within the TIC4747-related protein toxin class.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: February 22, 2022
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jennifer L. Lutke, Eric Van Fleet
  • Patent number: 11253626
    Abstract: Provided is a use for a peptide in surface-treating a medical device or medical material to be used in contact with blood, with which it is possible to obtain a medical device or medical material that can achieve highly efficient vascular endothelialization through the use of a peptide uniquely binding to vascular endothelial cells. Also provided are: a peptide suitable for use in said surface treatment; a method for producing a medical device or medical material surfaced-treated with said peptide and to be used in contact with blood; and a surface treatment agent including said peptide, said agent to be used in surface-treating a medical device or medical material to be used in contact with blood. In the present invention, a medical device or medical material is surface-treated using a peptide that includes any one of ten specific amino acid sequences and uniquely binds to the surface of endothelial progenitor cells.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: February 22, 2022
    Assignees: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, JMS CO., LTD.
    Inventors: Tetsuji Yamaoka, Maria Chiara Munisso, Atsushi Mahara, Takashi Yamamoto
  • Patent number: 11254945
    Abstract: Herein is disclosed synthetic oligonucleotides comprising 2?F-ANA nucleosides that can be utilized to control plant-chewing and phloem-feeding insects, bacteria present in such insects, and bacteria present in plants. The novel approaches and materials provided herein allow for reduction of pesticide and antibiotic use without the need to create genetically modified plants.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: February 22, 2022
    Assignees: The United States of America, as represented by The Secretary of Agriculture, AUM Lifetech, Inc.
    Inventors: Wayne B. Hunter, Veenu Aishwarya
  • Patent number: 11225672
    Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: January 18, 2022
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Krishnakumar Sridharan
  • Patent number: 11198888
    Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: December 14, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
  • Patent number: 11198887
    Abstract: The invention provides a transgenic corn event MON 95379, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379. The invention also provides polynucleotides specific for event MON 95379 and methods for using and detecting event MON 95379 as well as plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: December 14, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Heather M. Anderson, Sarah L. Brown, Renato A. Carvalho, Ancideriton A. Castro, Katherine M. Dunkmann, Adam J. Evans, Stanislaw Flasinski, Cara L. Griffith, Tianxiang Shen, Todd R. Smith, Heidi M. Windler
  • Patent number: 11193138
    Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: December 7, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
  • Patent number: 11186837
    Abstract: The present invention provides methods for controlling invertebrate pest infestations, for instance in plants, and related compositions and polynucleotides useful in such methods. More specifically, the present invention provides polynucleotides and methods of use thereof for modifying the expression of genes in an invertebrate pest, for instance through RNA interference.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: November 30, 2021
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Lex Evan Flagel, Gerrit Cornelis Segers, James K. Roberts
  • Patent number: 11180795
    Abstract: Methods for conveying soy cyst nematode (SCN) resistance into non-resistant soybean germplasm are provided. In some embodiments, the methods include introgression SCN resistance into a non-resistant soybean using one or more nucleic acid markers for marker-assisted breeding among soybean lines to be used in a soybean breeding program, wherein the markers are linked to and/or associated with SCN resistance. Also provided are single nucleotide polymorphisms (SNPs) associated with resistance to SCN. Soybean plants and seeds produced by any of the disclosed methods are provided.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: November 23, 2021
    Assignee: Syngenta Participations AG
    Inventors: Ainong Shi, Becky Welsh Breitinger, Ju-Kyung Yu, Azhaguvel Perumal
  • Patent number: 11161914
    Abstract: The present invention provides a human-derived molecularly modified insecticidal protein, and a preparation method and application thereof, and belongs to the field of genetic engineering and biological control. The present invention provides a human-derived molecularly modified insecticidal protein, and the amino acid sequence of the insecticidal protein CCL-CCL_scFv is shown as SEQ ID No. 1. The insecticidal protein CCL-CCL_scFv shows significantly higher affinity with midgut BBMV of Plutella xylostella than Cry1Ab toxin, competes with Cry1Ab and Cry1Ac toxins for binding the midgut BBMV of Plutella xylostella, and is a mimic of Cry1Ab and Cry1Ac toxins. Through Plutella xylostella indoor insecticidal biological activity assay, the insecticidal protein shows a good insecticidal effect, and can effectively replace Cry1Ac or Cry1Ab toxin for biological control of insect pest.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: November 2, 2021
    Assignee: Jiangsu Academy of Agricultural Sciences
    Inventors: Xianjin Liu, Yajing Xie, Chongxin Xu, Xiao Zhang, Meijing Gao, Xin He, Yuan Liu, Cunzheng Zhang
  • Patent number: 11130964
    Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, TIC11239, TIC11243, TIC11256, TIC4544, TIC4545, TIC6871, TIC7429, TIC7497, TIC7511, TIC7513, TIC7518, TIC7524, TIC7526, TIC7528, TIC7535 and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: September 28, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
  • Patent number: 11124802
    Abstract: Methods are provided for modulating an abiotic stress response to drought in a plant, for example by introducing a heritable change to the plant, which alters the expression in the plant of an endogenous or exogenous protein that is a member of a particular gene family, the Kanghan genes. Similarly, plants and plants cells having such heritable changes are provided.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: September 21, 2021
    Assignee: National Research Council of Canada
    Inventors: Jitao Zou, Wenyun Shen, Peng Gao
  • Patent number: 11124792
    Abstract: Disclosed herein are polynucleotides, compositions, and methods for controlling insect pests, especially flea beetles, such as Phyllotreta spp. and Psylliodes spp., particularly in plants. More specifically, polynucleotides such as double-stranded RNA triggers and methods of use thereof for modifying the expression of genes in flea beetles.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: September 21, 2021
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: Michael John Crawford, Brian Donovan Eads
  • Patent number: 11118189
    Abstract: Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 14, 2021
    Assignee: Ceres, Inc.
    Inventors: Roger I. Pennell, Richard Hamilton, Delin Liang
  • Patent number: 11091772
    Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: August 17, 2021
    Assignee: BASF Agricultural Solutions Seed US LLC
    Inventors: James Doroghazi, Duane Lehtinen, Elyse Ann Rodgers-Vieira, Jongmin Baek
  • Patent number: 11091520
    Abstract: The present invention is directed to the vegetative insecticidal proteins (Vips) modified to comprise heterologous bacterial carbohydrate binding modules and the methods of use thereof. Expression of modified proteins resulted in variations to activity against lepidopteran pest species of agricultural importance such as Corn earworm and Fall armyworm conveying broad spectrum insect control.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: August 17, 2021
    Assignee: Syngenta Participations AG
    Inventor: Joseph M. Watts
  • Patent number: 11085052
    Abstract: Provided herein are plants that reduce growth of a fungal pathogen, increase resistance of the plant to a fungal pathogen, or a combination thereof. The plant includes a polynucleotide that reduces expression of a coding region present in a fungal pathogen, such as Sclerotinia sclerotiorum or Botrytis cinerea. The polynucleotide can be present on the surface of the plant, expressed by a plant, or a combination thereof. Also provided are methods of making and methods of using the plants.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: August 10, 2021
    Assignee: University of Manitoba
    Inventors: Steve Whyard, Mark Belmonte
  • Patent number: 11085051
    Abstract: The present invention relates to methods of increasing pathogen resistance in a plant or a part of a plant. In one aspect, the method comprises contacting the plant or the part of the plant with a double-stranded RNA or a small RNA duplex that targets a fungal dicer-like (DCL) gene, wherein the plant or the part of the plant has increased resistance to a fungal pathogen compared to a control plant or control plant part that has not been contacted with the double-stranded RNA or small RNA duplex.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: August 10, 2021
    Assignee: The Regents of the University of California
    Inventor: Hailing Jin
  • Patent number: 11046972
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of insect pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in insect pests, including coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of insect pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: June 29, 2021
    Assignees: Dow AgroSciences LLC, Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
    Inventors: Kenneth E. Narva, Sarah E. Worden, Meghan Frey, Murugesan Rangasamy, Premchand Gandra, Wendy Lo, Elane Fishilevich, Andreas Vilcinskas, Eileen Knorr
  • Patent number: 11046974
    Abstract: The disclosure presents a platform for discovering novel insecticidal proteins from highly heterogeneous environmental sources. The methodology utilizes metagenomic enrichment procedures and unique genetic amplification techniques, which enables access to a broad class of unknown microbial diversity and their resultant proteome. The disclosed insecticidal protein discovery platform (IPDP) can be computationally driven and is able to integrate molecular biology, automation, and advanced machine learning protocols. The platform will enable researchers to rapidly and accurately access the vast repertoire of untapped insecticidal proteins produced by uncharacterized and complex microbial environmental samples. Also presented herein are a group of newly discovered pore-forming toxins (PFT) from a rare class of insecticidal proteins, which were discovered utilizing the insecticidal protein discovery platform.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: June 29, 2021
    Assignee: Zymergen Inc.
    Inventors: William W. Hwang, Jeffrey Kim, Oliver Liu, Jennifer Shock
  • Patent number: 11033622
    Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor “programmed death 1” (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 as well as the interaction of CTLA4 with CD86 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: June 15, 2021
    Assignee: Leidos, Inc.
    Inventors: Gabriel M. Gutierrez, Vinayaka Kotraiah, Timothy W. Phares, James Pannucci
  • Patent number: 11028134
    Abstract: The present invention is directed to the vegetative insecticidal proteins (Vips) modified to comprise heterologous bacterial carbohydrate binding modules and the methods of use thereof. Expression of modified proteins resulted in variations to activity against lepidopteran pest species of agricultural importance such as Corn earworm and Fall armyworm conveying broad spectrum insect control.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: June 8, 2021
    Assignee: Syngenta Participations AG
    Inventor: Joseph M. Watts
  • Patent number: 11015207
    Abstract: Provided are pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: May 25, 2021
    Assignee: The Regents of the University of California
    Inventor: Hailing Jin
  • Patent number: 11008371
    Abstract: The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: May 18, 2021
    Inventors: Andre Roger Abad, Andrew Carl Crow, Brad Poland, Jimei Wang
  • Patent number: 10939656
    Abstract: The invention relates to the novel cotton variety designated 16R228NRB2XF. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 16R228NRB2XF. Also provided by the invention are methods of using cotton variety 16R228NRB2XF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 16R228NRB2XF with itself or another cotton variety and plants and seeds produced by such methods.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: March 9, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Vivek Sharma, Robert E. McGowen
  • Patent number: 10941398
    Abstract: The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: March 9, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Gregory R. Heck, Tichafa R. I. Munyikwa, Jean C. Goley, James K. Roberts, Scott C. Johnson, Ty T. Vaughn
  • Patent number: 10941413
    Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in plants and/or plant cells. This is achieved by increasing the expression of a CASAR protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the order Pucciniales, preferably the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding a CASAR protein.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: March 9, 2021
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Holger Schultheiss, Nadine Tresch, Ralf Flachmann
  • Patent number: 10934330
    Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: March 2, 2021
    Assignee: Syngenta Participations AG
    Inventors: Yan Gao, Jared Conville, Jeng Shong Chen
  • Patent number: 10932471
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: March 2, 2021
    Inventors: Denny Joseph Bruck, Frederick C. Burns, II, James Kevin Presnail
  • Patent number: 10905127
    Abstract: The present disclosure provides compositions comprising Corn Rootworm (CRW)-active Methylobacterium sp., methods for controlling CRW, and methods of making the compositions. Also provided are isolated CRW-active Methylobacterium sp.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: February 2, 2021
    Assignee: NEWLEAF SYMBIOTICS, INC.
    Inventors: Marcus Jones, Gregg Bogosian
  • Patent number: 10870862
    Abstract: The invention relates to a method to change the capacity of a plant for adaptation to changes in the zinc concentration in the environment, especially the soil, comprising providing said plant with a nucleotide according to SEQ ID NO:1 or SEQ ID NO: 2 or an ortholog thereof. Such a method is especially useful to decrease Zn deficiency or to (hyper)accumulate Zn in plants for bioremediation or for biofortification. Transgenic plants for these proteins are also disclosed.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: December 22, 2020
    Assignee: WAGENINGEN UNIVERSITEIT
    Inventors: Ana Gonçalves Leite De Assunçao, Martinus Gerardus Maria Aarts
  • Patent number: 10858668
    Abstract: The present disclosure provides maize plants exhibiting broad spectrum resistance to Northern Leaf Blight (NLB). Maize plants with multiple NLB resistance loci located in cis linkage on chromosome 8 are provided. Compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are further provided.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: December 8, 2020
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: Bart Willem Brugmans, Jonathan Tyler Eckard, David Elon Fisher, Tim J. Gustafson, Chad Kramer
  • Patent number: 10851386
    Abstract: System, including methods and compositions, for making and using transgenic plants capable of metabolizing phosphite to reduce competition from weeds. The plants may be transgenically modified to express a phosphite dehydrogenase enzyme capable of catalyzing oxidation of phosphite to phosphate and grown in the presence of sufficient phosphite to selectively promote growth of the plant relative to weeds near the plant.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: December 1, 2020
    Assignee: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV)
    Inventors: Luis Rafael Herrera-Estrella, Damar Lisbeth López-Arredondo
  • Patent number: 10837067
    Abstract: The present disclosure is in the field of plant breeding and disease resistance. The disclosure provides methods for breeding corn plants having late wilt (LW) resistance using marker-assisted selection. The disclosure further provides corn germplasm resistant to LW. The disclosure also provides markers associated with LW resistance loci for introgressing these loci into elite germplasm in a breeding program, thus producing novel LW resistant germplasm.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: November 17, 2020
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: Rakesh B, Sunil Kumar Biradar, Franck Jean Chopin, Romain Fouquet, Sonali Dilip Gandhi, Erappa Gangappa, Veeresh R P Gowda, Yule Pan, Jean-Luc Pellet, Dharanendra Swamy, Gonzalo Torres, Chongqing Xie
  • Patent number: 10829781
    Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: November 10, 2020
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
  • Patent number: 10822609
    Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: November 3, 2020
    Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, Universidade Federal do Rio Grande do Sul
    Inventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
  • Patent number: 10808261
    Abstract: The present invention relates to the field of double-stranded RNA (dsRNA)-mediated gene silencing in insect species. More particularly, the present invention relates to genetic constructs designed for the expression of dsRNA corresponding to novel target genes in the insect pest Lymantria dispar, commonly known as the gypsy moth. The present invention also provides methodologies for introducing dsRNA into target insects to induce RNA interference. These constructs are particularly useful in RNAi-mediated control of the gypsy moth.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: October 20, 2020
    Assignee: The United States of America, as represented by The Secretary of Agriculture
    Inventors: Dawn E. Gundersen-Rindal, Saikat Kumar B. Ghosh
  • Patent number: 10793610
    Abstract: Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptide sequences having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the pesticidal polypeptides, DNA constructs comprising the nucleic acid molecules, vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the pesticidal polypeptides. Nucleotide sequences encoding the polypeptides provided herein can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest, including microorganisms and plants. The compositions and methods provided herein are useful for the production of organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: October 6, 2020
    Assignee: AgBiome, Inc.
    Inventors: Jessica Parks, Kira Bulazel Roberts, Rebecca E. Thayer
  • Patent number: 10781454
    Abstract: Disclosed herein are viral vectors based on modifications of the Citrus Tristeza virus useful for transfecting citrus trees for beneficial purposes. Included in the disclosure are viral vectors including one or more gene cassettes that encode heterologous polypeptides. The gene cassettes are positioned at desirable locations on the viral genome so as to enable expression while preserving functionality of the virus. Also disclosed are methods of transfecting plants and plants transfected with viral vector embodiments.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: September 22, 2020
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: William O. Dawson, Svetlana Folimonova, Choaa Amine El Mohtar, Siddarame Gowda, Subhas Hajeri
  • Patent number: 10781457
    Abstract: The disclosure relates to a method for increasing the resistance of a plant to a plant RNA virus, comprising expressing in said plant a mutant protein-only RNase P enzyme lacking a nuclear localization signal domain or an organelle targeting sequence domain, and related compositions.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: September 22, 2020
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Philippe Giege, Anthony Gobert
  • Patent number: 10760094
    Abstract: The present invention concerns a transgenic plant of the species Solanum tuberosum with a resistance to an oomycete of the genus Phytophthora, transgenic parts of such a plant, a method for its manufacture and to a composition for external application to plants. On the one hand, nucleotide sequences in accordance with SEQ ID NOS: 1-43 are provided from Phytophthora in a host plant-induced gene silencing strategy in potato plants; on the other hand, a fungicide for plant treatment is provided.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: September 1, 2020
    Assignee: KWS SAAT SE & CO. KGAA
    Inventors: Jurgen Dietmar Stahl, Nora Temme
  • Patent number: 10731225
    Abstract: This invention relates to polynucleotide sequences encoding genes that can confer resistance to the plant pathogen Colletotrichum, which causes anthracnose stalk rot, leaf blight and top dieback in corn and other cereals. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resistance to the plant pathogen Colletotrichum, and processes of making said plants and seeds. The invention further presents sequences that can be used as molecular markers that in turn can be used to identify the region of interest in corn lines resulting from new crosses and to quickly and efficiently introgress the genes from corn lines carrying said genes into other corn lines that do not carry said genes, in order to make them resistant to Colletotrichum and resistant to stalk rot.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: August 4, 2020
    Assignee: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Karen E. Broglie, Karlene H Butler
  • Patent number: 10717988
    Abstract: The invention relates to a Brassica plant in particular a Brassica oleracea plant comprising a genetic determinant, which when homozygously present confers high resistance against Thrips tabaci, and which is as found in plants grown from seeds of which a representative sample is deposited with the NCIMB under NCIMB accession number 41760. Preferably, the plant is homozygous for the genetic determinant and resistant against Thrips tabaci. The genetic determinant in the seeds of NCIMB deposit 41760 is located on chromosome 2 and linked to marker BO00200 (SEQ ID NO: 1) and/or marker BO00277 (SEQ ID NO: 2) and/or BO00602 (SEQ ID NO: 5).
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: July 21, 2020
    Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.
    Inventor: Harm Löptien
  • Patent number: 10683517
    Abstract: The subject invention relates in part to the surprising discovery that Cry1Da is active against corn earworm (CEW), Helicoverpa zea (Boddie). Methods for using Cry1Da in transgenic plants to prevent serious crop damage is described. Leaf and silk bioassays using transgenic maize expressing full length, core toxin region or chimeric Cry1Da demonstrated good insect protection against CEW larvae damage.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: June 16, 2020
    Assignee: AGRIGENETICS, INC.
    Inventors: Sek Yee Tan, Joel J. Sheets, Todd Glancy, Aaron T. Woosley, Sarah E. Worden, Diaa Alabed, Stephanie Burton, Karen C. McLaughlin, Kenneth E. Narva, Thomas Meade
  • Patent number: 10683516
    Abstract: Provided herein are Vitis vinifera exhibiting Erysiphe necator resistance. In particular, provided herein are Vitis vinifera having in their genome mildew resistance locus O (MLO) genes, in particular an MLO7 gene and an MLO6 gene, where the MLO7 gene and MLO6 gene have reduced expression and/or function.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: June 16, 2020
    Assignee: FONDAZIONE EDMUND MACH
    Inventors: Mickael Malnoy, Stefano Pessina, Riccardo Velasco, Michele Perazzolli, Luisa Lenzi
  • Patent number: 10676757
    Abstract: Insecticidal toxins derived from Bacillus thuringiensis, polynucleotides encoding such toxins, use of such toxins to control plant pests, and transgenic plants that produce, and are protected, by these toxins are described.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: June 9, 2020
    Assignee: DOW AGROSCIENCES LLC
    Inventors: Timothy D. Hey, Janna Mai Armstrong, Ted Letherer, Audrey Jane Etter, Meghan L. Frey, Haley Ellis, Kenneth E. Narva, Xiaoping Xu, Krishna M. Madduri, Sek Yee Tan, Premchand Gandra
  • Patent number: 10676745
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 9, 2020
    Assignee: Dow AgroSciences LLC
    Inventors: Kenneth E. Narva, Kanika Arora, Muregesan Rangasamy, Balaji Veeramani, Premchand Gandra, Sarah E. Worden, Huarong Li, Andreas Vilcinskas, Eileen Knorr