The Polynucleotide Confers Pathogen Or Pest Resistance Patents (Class 800/279)
  • Patent number: 10344291
    Abstract: dsRNA generated from D. citri trehalase gene is effective in reducing fitness and/or survival of D. citri. Thus genetically altered plants expressing the dsRNA and plants to which dsRNA solutions are applied increase D. citri mortality and reduce D. citri infestation. With reduced D. citri population, the spread of microorganisms for which D. citri is a vector is reduced. Such microorganisms include, but are not limited to, C. Liberibacter species, including: CLas, CLam, and CLaf. Thus, applying of the D. citri trehalase dsRNA to a plant reduces disease and/or microorganism transmission by killing D. citri that feed on the treated plant.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: July 9, 2019
    Assignees: The United States of America, as Represented by the Secretary of Agriculture, Empresa Brasileira De Pesquisa Agropecuaria
    Inventors: Wayne B. Hunter, Maria T. Gonzalez, Eduardo C. Andrade
  • Patent number: 10301623
    Abstract: This invention discloses recombinant DNA constructs encoding phased small RNAs useful in regulating expression of one or more genes of interest. Also disclosed by this invention are transgenic plant cells, plants, and seeds containing a recombinant DNA construct of this invention.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: May 28, 2019
    Assignee: Monsanto Technology LLC
    Inventors: Edwards Allen, Liang Guo, Sara E. Heisel, Sergey I. Ivashuta, Yuanji Zhang
  • Patent number: 10280197
    Abstract: A method of selectively modulating the activity of C5a receptor 2 (C5aR2). The method includes exposing the receptor to a compound that selectively modulates C5aR2 compared to C5a receptor 1 (C5aR1). In some cases, the compound is peptide P32 or P59. Methods of recruiting ?-arrestin 2 in a cell, modulating C5a-induced ERK1/2 activation in a macrophage, selectively inhibiting the release of IL-6 from a macrophage, are also provided.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: May 7, 2019
    Assignees: The Regents of the University of California, The Texas A & M University System, The University of Queensland, The University of Sheffield
    Inventors: Dimitrios Monikis, Christodoulos Floudas, Trent Woodruff, Matthew A. Cooper, Daniel E. Croker, Peter N. Monk
  • Patent number: 10251352
    Abstract: The present invention relates to methods for identifying cucumber lines having increased resistance to Downy Mildew, and identification of genetic markers linked to gene(s) conditioning such increased disease resistance. The present invention also relates to methods of breeding cucumber plants from lines having increased Downy Mildew resistance by marker-assisted selection, compositions including nucleic acid probes or primers which are useful for such marker assisted selection, and plants and plant parts produced by such methods.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: April 9, 2019
    Assignee: SEMINIS VEGETABLE SEEDS, INC.
    Inventors: David Caldwell, Eva King-Fan Chan, Jeroen de Vries, Tarek Joobeur, Joseph J. King, Antonio Reina, Nischit Shetty
  • Patent number: 10246722
    Abstract: Methods of inhibiting plant parasitic nematodes, methods of obtaining transgenic plants useful for inhibiting such nematodes, and transgenic plants that are resistant to plant parasitic nematodes through inhibition of plant nematode CLAVATA3/ESR (CLE) peptide receptor genes are provided. Methods for expressing genes at plant parasitic nematode feeding sites with plant nematode CLE peptide receptor gene promoters are also provided, along with nematode CLE peptide receptor gene promoters that are useful for expressing genes in nematode feeding sites as well as transgenic plants and nematode resistant transgenic plants comprising the promoters.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: April 2, 2019
    Assignees: The Curators of the University of Missouri, Cornell University, The United States of America, as Represented by the Secretary of Agriculture
    Inventors: Melissa G. Mitchum, Amy Replogle, Jianying Wang, Xiaohong Wang, Shiyan Chen, Ping Lang
  • Patent number: 10232012
    Abstract: A pH-responsive fusion peptide according to the present disclosure, containing a cell-penetrating peptide exhibiting a positive charge, which contains 2-15 arginine residues, and a ?-sheet-forming segment, experiences structural change depending on pH change. Due to the structural change, the anti-prion activity and cytotoxicity of the fusion peptide can be controlled as desired.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: March 19, 2019
    Assignees: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
    Inventors: Yong beom Lim, Chong suk Ryou
  • Patent number: 10221431
    Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2-3, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: March 5, 2019
    Assignee: Athenix Corp.
    Inventors: Kira Roberts, Kimberly S. Sampson, Duane Lehtinen, Leonardo Magalhaes
  • Patent number: 10221429
    Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:21-74, or the nucleotide sequence set forth in SEQ ID NO: 1-20, as well as variants and fragments thereof.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: March 5, 2019
    Assignee: Bayer CropScience LP
    Inventors: Rebecca Thayer, Kimberly S. Sampson, Duane Lehtinen, Cheryl Peters, Kira Roberts, Leonardo Magalhaes, Ethan Dunn
  • Patent number: 10196633
    Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: February 5, 2019
    Assignee: Syngenta Participations AG
    Inventors: Yan Gao, Jared Conville, Jeng Shong Chen
  • Patent number: 10190134
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the expression of a target sequence in the pest. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 6-12, 18-40 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 29, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Brian McGonigle, James Kevin Presnail, Navdeep Singh Mutti
  • Patent number: 10190126
    Abstract: This application provides and discloses small RNAs and their target genes that are involved in controlling the levels of sucrose, glucose, and fructose and methods of modulating expression or activity of these mi RNAs and target genes. This application further provides transgenic plants, plant parts, e.g., seeds, that have altered expression of these mi RNAs and target genes and have increased levels of sucrose, increased sucrose to glucose ratios, increased sucrose to hexose ratios, altered carbohydrate levels, or increased Brix in fruit from transgenic plants. This application also provides methods of producing and growing transgenic plants or seeds that have increased levels of sucrose, increased sucrose to glucose ratios, increased sucrose to hexose ratios, altered carbohydrate levels, or increased Brix in fruit from transgenic plants.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: January 29, 2019
    Assignee: A.B. Seeds Ltd.
    Inventors: Rudy Maor, Iris Nesher
  • Patent number: 10184130
    Abstract: Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased resource use efficiency, increased water use efficiency, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: January 22, 2019
    Assignee: KOCH BIOLOGICAL SOLUTIONS, LLC
    Inventors: Graham J. Hymus, T. Lynne Reuber, Colleen M. Marion, Oliver J. Ratcliffe, Jeffrey M. Libby
  • Patent number: 10174339
    Abstract: This disclosure relates generally to the field of anti-pathogenic agents, including a modified defensin molecule with anti-pathogen activity. Genetically modified plants and their progeny or parts expressing or containing the modified defensin and anti-pathogen compositions for use in horticulture and agriculture and as animal and human medicaments are also provided.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: January 8, 2019
    Assignee: Hexima Limited
    Inventors: Nicole Van Der Weerden, Marilyn Anne Anderson
  • Patent number: 10174340
    Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: January 8, 2019
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
  • Patent number: 10155960
    Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: December 18, 2018
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Uma R. Kesanapalli, Jennifer L. Lutke
  • Patent number: 10119148
    Abstract: The present invention relates to pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: November 6, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Hailing Jin
  • Patent number: 10106810
    Abstract: The invention relates to a method to change the capacity of a plant for adaptation to changes in the zinc concentration in the environment, especially the soil, comprising providing said plant with a nucleotide according to SEQ ID NO:1 or SEQ ID NO: 2 or an ortholog thereof. Such a method is especially useful to decrease Zn deficiency or to (hyper)accumulate Zn in plants for bioremediation or for biofortification. Transgenic plants for these proteins are also disclosed.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 23, 2018
    Assignee: WAGENINGEN UNIVERSITEIT
    Inventors: Ana Goncalves Leite De Assuncao, Martinus Gerardus Maria Aarts
  • Patent number: 10093946
    Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a Bacillus thuringiensis toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:5-26, or the nucleotide sequence set forth in SEQ ID NO: 1-4, as well as variants and fragments thereof.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: October 9, 2018
    Assignee: BASF SE
    Inventors: Duane Alan Lehtinen, Kimberly S. Sampson, Kira Roberts, Ethan Dunn
  • Patent number: 10093945
    Abstract: The present invention relates to the field of double-stranded RNA (dsRNA)-mediated gene silencing in insect species. More particularly, the present invention relates to genetic constructs designed for the expression of dsRNA corresponding to novel target genes in the insect pest Lymantria dispar, commonly known as the gypsy moth. The present invention also provides methodologies for introducing dsRNA into target insects to induce RNA interference. These constructs are particularly useful in RNAi-mediated control of the gypsy moth.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: October 9, 2018
    Assignee: The United States of America, as represented by The Secretary of Agriculture
    Inventors: Dawn E. Gundersen-Rindal, Saikat Kumar B. Ghosh
  • Patent number: 10053706
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: August 21, 2018
    Assignees: Dow AgroSciences LLC, The Board of Regents of the University of Nebraska
    Inventors: Blair D. Siegfried, Kenneth E. Narva, Kanika Arora, Sarah E. Worden, Chitvan Khajuria, Elane Fishilevich, Nicholas P. Storer, Meghan Frey, Ronda L. Hamm, Ana Velez
  • Patent number: 10047374
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: August 14, 2018
    Assignees: Dow AgroSciences LLC, The Board of Regents of the University of Nebraska
    Inventors: Blair D. Siegfried, Kenneth E. Narva, Kanika Arora, Sarah E. Worden, Chitvan Khajuria, Elane Fishilevich, Nicholas P. Storer, Meghan Frey, Ronda L. Hamm, Ana Velez
  • Patent number: 10039258
    Abstract: The present disclosure provides for unique spinach plants with broad-spectrum resistance to downy mildew and their progeny. Such plants may comprise an introgressed QTL associated with the broad-spectrum resistance to downy mildew. In certain aspects, compositions, including distinct polymorphic molecular markers, and methods for producing, using, identifying, selecting, and the like of plants or germplasm with resistance to downy mildew are provided.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: August 7, 2018
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: Bart Willem Brugmans, Eduardo López Fernandez, Inge Weber
  • Patent number: 10041088
    Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in plants and/or plant cells. This is achieved by increasing the expression of a CASAR protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the order Pucciniales, preferably the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding a CASAR protein.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: August 7, 2018
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Holger Schultheiss, Nadine Tresch, Ralf Flachmann
  • Patent number: 10023876
    Abstract: Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide sequences encoding the pesticidal polypeptide can be used to transform various prokaryotic and eukaryotic organisms, which organisms can be used to produce the pesticidal polypeptides. The recombinant organisms and/or the polypeptides produced by the recombinant organisms can be used to control pests in various environments.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: July 17, 2018
    Inventors: Mikyong Lee, Jeng Shong Chen, Cheryl Marie De Fontes, Jared Conville, Narendra Palekar
  • Patent number: 10023877
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: July 17, 2018
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A. Patten, Takashi Yamamoto
  • Patent number: 10017747
    Abstract: Disclosed herein are viral vectors based on modifications of the Citrus Tristeza virus useful for transfecting citrus trees for beneficial purposes. Included in the disclosure are viral vectors including one or more gene cassettes that encode heterologous polypeptides. The gene cassettes are positioned at desirable locations on the viral genome so as to enable expression while preserving functionality of the virus. Also disclosed are methods of transfecting plants and plants transfected with viral vector embodiments.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: July 10, 2018
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: William O. Dawson, Svetlana Folimonova, Choaa Amine El Mohtar, Siddarame Gowda, Subhas Hajeri
  • Patent number: 9994844
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: June 12, 2018
    Assignees: Dow AgroSciences LLC, The Board of Regents of the University of Nebraska
    Inventors: Blair D. Siegfried, Kenneth E. Narva, Kanika Arora, Sarah E. Worden, Chitvan Khajuria, Elane Fishilevich, Nicholas P. Storer, Meghan Frey, Ronda L. Hamm, Ana M. Velez
  • Patent number: 9994920
    Abstract: Various methods and compositions are provided for identifying and/or selecting soybean plants or soybean germplasm with resistance or improved resistance to soybean cyst nematode. In certain embodiments, the method comprises detecting at least one marker locus that is associated with resistance to soybean cyst nematode. In other embodiments, the method further comprises detecting at least one marker profile or haplotype associated with resistance to soybean cyst nematode. In further embodiments, the method comprises crossing a selected soybean plant with a second soybean plant. Further provided are markers, primers, probes and kits useful for identifying and/or selecting soybean plants or soybean germplasm with resistance or improved resistance to soybean cyst nematode.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: June 12, 2018
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Joshua M Shendelman, John B Woodward, Meizhu Yang
  • Patent number: 9988642
    Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: June 5, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
  • Patent number: 9957522
    Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the family Phacopsoraceae in plants and/or plant cells. This is achieved by increasing the expression of a CASAR protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding a CASAR protein.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: May 1, 2018
    Assignee: BASF PLANT SCIENCE COMPANY GMBH
    Inventors: Holger Schultheiss, Nadine Tresch, Ralf Flachmann
  • Patent number: 9957524
    Abstract: The invention generally relates to the field of insect inhibitory toxin proteins. A novel class of proteins exhibiting insect inhibitory activity against agriculturally relevant pests of crop plants and seeds are disclosed. Insecticidal activity is particularly effective against the Coleopteran order of insect pests. Plants, plant parts, and seed are provided containing a polynucleotide construct encoding one or more of the toxin proteins disclosed herein. The proteins are referred to herein variously as the TIC2463-related toxin protein class or family, the TIC2463-related toxin proteins, the TIC2463-related protein genus, toxin proteins related to the TIC2463 toxin protein, proteins related to TIC2463, TIC2463-related toxin polypeptides, TIC2463-related pesticidal proteins, and the like.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: May 1, 2018
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Xiaoran Fu, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Daqi Tu, Andrew M. Wollacott, Yong Yin
  • Patent number: 9957523
    Abstract: The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for making transgenic plants that express the double stranded RNA molecules, as well as pesticidal agents and commodity products produced by the inventive plants.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: May 1, 2018
    Assignee: Devgen NV
    Inventors: Romaan Raemaekers, Pascale Feldmann, Irene Nooren, Geert Plaetinck, Frederic Pecqueur, Els Van Bleu, Thierry Bogaert
  • Patent number: 9944948
    Abstract: The present invention relates to the prevention and/or control of infestation by insect pest species. In particular, the invention relates to down-regulation of expression of target genes in insect pests using interfering ribonucleic acid (RNA) molecules. Also described are transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species. Compositions containing the interfering RNAs of the invention are also provided.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: April 17, 2018
    Assignee: Devgen NV
    Inventors: Thierry Bogaert, Romaan Raemaekers, Yann Naudet
  • Patent number: 9932575
    Abstract: The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides. The scaffolds are particularly well suited for constructing libraries, e.g., in phage display or related systems. The invention also relates to various uses of the scaffolds, including in therapy, diagnosis, environmental and security monitoring, synthetic biology and research, and to cells and cell cultures expressing the scaffold proteins.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: April 3, 2018
    Assignee: University of Leeds
    Inventors: Michael McPherson, Darren Tomlinson
  • Patent number: 9932603
    Abstract: The present invention is related to a method for conveying viral resistance or tolerance to one or more virus(es), in particular to beet mild yellowing virus (BMYV) and to beet necrotic yellow vein virus (BNYVV) or to BMYV alone in a plant, in particular in a sugar beet plant. Furthermore, the present invention relates to the virus resistant or -tolerant plant obtained according to this method, as well as to seeds and progeny derived therefrom.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: April 3, 2018
    Assignee: SESVANDERHAVE NV
    Inventors: Elodie Klein, Véronique Graff, David Gilmer, Véronique Brault, Guy Weyens, Marc Lefebvre
  • Patent number: 9879277
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 30, 2018
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Andre R. Abad, Zhenglin Hou, Lu Liu, Brad Poland, Ute Schellenberger, Ingrid Udranszky, Jimei Wang, Jun-Zhi Wei, Thomas C. Wolfe, Weiping Xie, Lan Zhou, Genhai Zhu
  • Patent number: 9845479
    Abstract: The present invention relates to genetic control of infestation by insect pest species, particularly prevention and/or control of pest infestation of plants, using interfering ribonucleic acid (RNA) molecules. The invention provides transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: December 19, 2017
    Assignee: Devgen NV
    Inventors: Myriam Beghyn, Thierry Andre Olivier Eddy Bogaert, Pascale Feldmann, Romaan Raemaekers
  • Patent number: 9834785
    Abstract: A family 1 cellulose-binding-domain (CBD) encoding gene from Phytophthora infestans was used to develop transgenic Bintje potato plants. Tests with detached leaflets showed no evidence of increased or decreased resistance to P. infestans, in comparison with the susceptible Bintje controls. Changes in plant morphology were most evident in the CBD1 multicopy transgenics. Plant height increases were evident in the later growth stages, along with earlier flowering and the ability to produce seed balls. While Bintje control plants are male and female sterile, the multicopy transgenics were male sterile and female fertile. Crosses made into Bintje demonstrated the ability to transfer P. infestans targeted R genes, as well as genes responsible for color and tuber shape, into Bintje germplasm. Selection for the absence of the CBD1 transgene should allow for immediate use of the material.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: December 5, 2017
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Richard W. Jones, Frances G. Perez
  • Patent number: 9803204
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: October 31, 2017
    Inventors: Kenneth E. Narva, Huarong Li, Chaoxian Geng, Ignacio Larrinua, Monica Britt-Olson, Navin Elango, Mathew J. Henry
  • Patent number: 9770035
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: September 26, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: Kenneth E. Narva, Huarong Li, Chaoxian Geng, Ignacio Larrinua, Monica Britt Olson, Navin Elango
  • Patent number: 9695436
    Abstract: Methods are provided for enhancing yield and nitrogen use efficiency in plants, and to methods of increasing biomass and seed yield in plants grown under nitrogen limiting conditions using variants of enzymes involved in nitrogen assimilation or metabolism from non-plant organisms.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: July 4, 2017
    Assignee: BAYER CROPSCIENCE LP
    Inventors: Chandra McAllister, Perrin Beatty, Jayne D'Entremont, Allen Good
  • Patent number: 9695439
    Abstract: The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: July 4, 2017
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Claire A. CaJacob, Pascale Feldmann, Gregory R. Heck, Irene Maria Antonia Nooren, Geert Plaetinck, Ty T. Vaughn, Wendy Maddelein
  • Patent number: 9688984
    Abstract: Methods and compositions that affect grain shape, width, and yield in rice are disclosed. Methods of transgenic modulation and marker-assisted breeding methods improve grain length to width ratio and grain yield in rice. Down-regulation of OsSPL16 in rice resulted in increased grain quality.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: June 27, 2017
    Assignee: INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY
    Inventors: Xiangdong Fu, Shaokui Wang, Kun Wu, Guiquan Zhang, Ruizhen Zeng
  • Patent number: 9683242
    Abstract: The invention provides specific transgenic soybean plants, plant material and seeds, characterized in that these products harbor a stack of specific transformation events at specific locations in the soybean genome. Tools are also provided which allow rapid and unequivocal identification of these events in biological samples.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: June 20, 2017
    Assignees: M.S. Technologies, LLC, Bayer CropScience N.V.
    Inventors: Justin Thomas Mason, Leslie James Lettow, Mark Alan Eby, William H. Eby, Gunter Welz, Steven Verhaeghe, Marc De Beuckeleer, Veerle Habex, Jean-Marc Ferrulo
  • Patent number: 9681621
    Abstract: A novel maize variety designated PH1DG1 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1DG1 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1DG1 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1DG1 or a locus conversion of PH1DG1 with another maize variety.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: June 20, 2017
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Gustavo Marcelo Garcia
  • Patent number: 9670465
    Abstract: An object of the present invention is to provide a novel method of controlling TYLCV whereby the infection cycle of TYLCV can be broken. The present invention provides a novel virus that is not transmitted by an insect vector as a tomato yellow leaf curl virus. The present invention also provides a method of controlling a tomato yellow leaf curl disease and a method of preventing transmission of a yellow leaf curl virus by using a tomato yellow leaf curl virus not transmitted by an insect vector.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: June 6, 2017
    Assignee: KIKKOMAN CORPORATION
    Inventors: Hiroki Atarashi, Toshiro Inoue, Haruki Sayama, Hisashi Nishigawa, Tamotsu Murai, Tomohide Natsuaki
  • Patent number: 9663794
    Abstract: Provided in the present invention are a separated endogenous rice gene resistant to high temperature (hereinafter referred to as the OsZFP gene for short) and a polypeptide encoded thereby, optimizing rice cells comprising the heat-resistant gene of the present invention or the polypeptide encoded thereby, and the plant cell preparation method thereof. Further provided are new methods and technologies for breeding new varieties of heat-resistant crops, comprising the related regulatory sequence for heat-resistance and a closely linked molecular marker denoting the heat-resistant gene and the sequence thereof.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: May 30, 2017
    Assignees: Zhejiang University, Rice Research Institute, Guangdong Academy of Agricultural Sciences
    Inventors: Jumin Tu, Xuhua Zhong, Jianping Liu, Nongrong Huang
  • Patent number: 9655313
    Abstract: A novel maize variety designated PH1KKG and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KKG with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1KKG through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1KKG or a locus conversion of PH1KKG with another maize variety.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: May 23, 2017
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventor: Susanne Groh
  • Patent number: 9650647
    Abstract: The present invention provides nucleic acids and methods for conferring resistance to bacterial disease in plants. The present invention also provides promoters and promoter sequences useful for controlling expression in transgenic plants.
    Type: Grant
    Filed: September 6, 2010
    Date of Patent: May 16, 2017
    Assignee: Temasek Life Sciences Laboratory Limited
    Inventors: Zhong Chao Yin, Ke Yu Gu, Dong Sheng Tian
  • Patent number: 9635825
    Abstract: The present invention provides an inbred corn line designated ID6461, methods for producing a corn plant by crossing plants of the inbred line ID6461 with plants of another corn plant. The invention further encompasses all parts of inbred corn line ID6461, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line ID6461, and plants produced according to these methods.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: May 2, 2017
    Assignee: Syngenta Participations AG
    Inventor: Mohammed Ahmed