The Polynucleotide Confers Pathogen Or Pest Resistance Patents (Class 800/279)
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Patent number: 11365421Abstract: Provided are isolated polynucleotides comprising a nucleic acid sequence encoding a polypeptide at least 80% identical to SEQ ID NO: 422, 362-421, 423-601, 2429-4085 and 4086, such as a polynucleotide which is at least 80% identical to SEQ ID NO: 260, 1-259, 261-361, 602-2427 and 2428, nucleic acid constructs comprising same, plant cells comprising same, transgenic plants expressing same, and methods of generating thereof for increasing the yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, nitrogen use efficiency and/or abiotic stress tolerance of a plant.Type: GrantFiled: August 4, 2020Date of Patent: June 21, 2022Assignee: Evogene Ltd.Inventors: Noa Matarasso, Hagai Karchi
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Patent number: 11365423Abstract: Disclosed is a method for obtaining multileaflet Medicago sativa materials by means of MsPALM1 artificial site-directed mutants. The method comprises: selecting a target site from an exon region of a compound leaf developmental regulatory gene MsPALM1 of Medicago sativa and constructing a plant CRISPR/Cas9 editing recombinant vector MsCRISPR/Cas9::PALM1 and introducing the vector into Medicago sativa cells and regenerating into plants, cutting and repairing to cause a loss-of-function mutation in the MsPALM1 gene of Medicago sativa cells, and then screening the mutant plants by restriction endonuclease digestion and/or targeted deep sequencing of the target sites of the regenerated plants to obtain lines carrying four MsPALM1 allelic genes with simultaneous loss of function mutation. After phenotypic identification, it was confirmed that the compound leaves of the regenerated plants changed from three leaflets to five leaflets.Type: GrantFiled: January 5, 2021Date of Patent: June 21, 2022Assignee: GUANGDONG SANJIE FORAGE BIOTECHNOLOGY CO., LTDInventors: Haitao Chen, Wen Wang, Xiongping Xie, Qiang Qiu, Zhanhuan Shang, Kexian Su, Hui He
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Patent number: 11286495Abstract: Provided are methods of increasing nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence at least 80% identical to SEQ ID NO:1-467, 785-3047; or an exogenous polynucleotide encoding a polypeptide at least 80% identical to SEQ ID NO:468-784, 3048-4333, 4335-4682. Also provided isolated polynucleotide comprising a nucleic acid sequence selected from the group consisting of SEQ ID NOs:1-467, 785-3047, which can be used to increase nitrogen use efficiency, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality and/or abiotic stress tolerance of a plant.Type: GrantFiled: July 23, 2020Date of Patent: March 29, 2022Assignee: Evogene Ltd.Inventors: Basia Judith Vinocur, Alex Diber, Hagai Karchi
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Patent number: 11254950Abstract: Nucleotide sequences are disclosed encoding novel, insecticidal TIC4747 and related proteins exhibiting Hemipteran and Lepidopteran inhibitory activity, as well as fragments thereof. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing a polynucleotide construct encoding one or more of the toxin proteins within the TIC4747-related protein toxin class.Type: GrantFiled: February 28, 2020Date of Patent: February 22, 2022Assignee: Monsanto Technology LLCInventors: David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jennifer L. Lutke, Eric Van Fleet
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Patent number: 11253626Abstract: Provided is a use for a peptide in surface-treating a medical device or medical material to be used in contact with blood, with which it is possible to obtain a medical device or medical material that can achieve highly efficient vascular endothelialization through the use of a peptide uniquely binding to vascular endothelial cells. Also provided are: a peptide suitable for use in said surface treatment; a method for producing a medical device or medical material surfaced-treated with said peptide and to be used in contact with blood; and a surface treatment agent including said peptide, said agent to be used in surface-treating a medical device or medical material to be used in contact with blood. In the present invention, a medical device or medical material is surface-treated using a peptide that includes any one of ten specific amino acid sequences and uniquely binds to the surface of endothelial progenitor cells.Type: GrantFiled: January 30, 2018Date of Patent: February 22, 2022Assignees: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, JMS CO., LTD.Inventors: Tetsuji Yamaoka, Maria Chiara Munisso, Atsushi Mahara, Takashi Yamamoto
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Patent number: 11254945Abstract: Herein is disclosed synthetic oligonucleotides comprising 2?F-ANA nucleosides that can be utilized to control plant-chewing and phloem-feeding insects, bacteria present in such insects, and bacteria present in plants. The novel approaches and materials provided herein allow for reduction of pesticide and antibiotic use without the need to create genetically modified plants.Type: GrantFiled: July 3, 2019Date of Patent: February 22, 2022Assignees: The United States of America, as represented by The Secretary of Agriculture, AUM Lifetech, Inc.Inventors: Wayne B. Hunter, Veenu Aishwarya
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Patent number: 11225672Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention.Type: GrantFiled: October 21, 2019Date of Patent: January 18, 2022Assignee: Monsanto Technology LLCInventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Stanislaw Flasinski, Arlene R. Howe, Krishnakumar Sridharan
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Patent number: 11198888Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.Type: GrantFiled: November 14, 2019Date of Patent: December 14, 2021Assignee: Monsanto Technology LLCInventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
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Patent number: 11198887Abstract: The invention provides a transgenic corn event MON 95379, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379. The invention also provides polynucleotides specific for event MON 95379 and methods for using and detecting event MON 95379 as well as plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379.Type: GrantFiled: July 29, 2019Date of Patent: December 14, 2021Assignee: Monsanto Technology LLCInventors: Heather M. Anderson, Sarah L. Brown, Renato A. Carvalho, Ancideriton A. Castro, Katherine M. Dunkmann, Adam J. Evans, Stanislaw Flasinski, Cara L. Griffith, Tianxiang Shen, Todd R. Smith, Heidi M. Windler
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Patent number: 11193138Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.Type: GrantFiled: November 14, 2019Date of Patent: December 7, 2021Assignee: Monsanto Technology LLCInventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
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Patent number: 11186837Abstract: The present invention provides methods for controlling invertebrate pest infestations, for instance in plants, and related compositions and polynucleotides useful in such methods. More specifically, the present invention provides polynucleotides and methods of use thereof for modifying the expression of genes in an invertebrate pest, for instance through RNA interference.Type: GrantFiled: December 8, 2016Date of Patent: November 30, 2021Assignee: Monsanto Technology LLCInventors: James A. Baum, Lex Evan Flagel, Gerrit Cornelis Segers, James K. Roberts
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Patent number: 11180795Abstract: Methods for conveying soy cyst nematode (SCN) resistance into non-resistant soybean germplasm are provided. In some embodiments, the methods include introgression SCN resistance into a non-resistant soybean using one or more nucleic acid markers for marker-assisted breeding among soybean lines to be used in a soybean breeding program, wherein the markers are linked to and/or associated with SCN resistance. Also provided are single nucleotide polymorphisms (SNPs) associated with resistance to SCN. Soybean plants and seeds produced by any of the disclosed methods are provided.Type: GrantFiled: June 2, 2016Date of Patent: November 23, 2021Assignee: Syngenta Participations AGInventors: Ainong Shi, Becky Welsh Breitinger, Ju-Kyung Yu, Azhaguvel Perumal
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Patent number: 11161914Abstract: The present invention provides a human-derived molecularly modified insecticidal protein, and a preparation method and application thereof, and belongs to the field of genetic engineering and biological control. The present invention provides a human-derived molecularly modified insecticidal protein, and the amino acid sequence of the insecticidal protein CCL-CCL_scFv is shown as SEQ ID No. 1. The insecticidal protein CCL-CCL_scFv shows significantly higher affinity with midgut BBMV of Plutella xylostella than Cry1Ab toxin, competes with Cry1Ab and Cry1Ac toxins for binding the midgut BBMV of Plutella xylostella, and is a mimic of Cry1Ab and Cry1Ac toxins. Through Plutella xylostella indoor insecticidal biological activity assay, the insecticidal protein shows a good insecticidal effect, and can effectively replace Cry1Ac or Cry1Ab toxin for biological control of insect pest.Type: GrantFiled: August 8, 2019Date of Patent: November 2, 2021Assignee: Jiangsu Academy of Agricultural SciencesInventors: Xianjin Liu, Yajing Xie, Chongxin Xu, Xiao Zhang, Meijing Gao, Xin He, Yuan Liu, Cunzheng Zhang
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Patent number: 11130964Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, TIC11239, TIC11243, TIC11256, TIC4544, TIC4545, TIC6871, TIC7429, TIC7497, TIC7511, TIC7513, TIC7518, TIC7524, TIC7526, TIC7528, TIC7535 and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention.Type: GrantFiled: November 30, 2018Date of Patent: September 28, 2021Assignee: Monsanto Technology LLCInventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
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Patent number: 11124802Abstract: Methods are provided for modulating an abiotic stress response to drought in a plant, for example by introducing a heritable change to the plant, which alters the expression in the plant of an endogenous or exogenous protein that is a member of a particular gene family, the Kanghan genes. Similarly, plants and plants cells having such heritable changes are provided.Type: GrantFiled: September 14, 2018Date of Patent: September 21, 2021Assignee: National Research Council of CanadaInventors: Jitao Zou, Wenyun Shen, Peng Gao
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Patent number: 11124792Abstract: Disclosed herein are polynucleotides, compositions, and methods for controlling insect pests, especially flea beetles, such as Phyllotreta spp. and Psylliodes spp., particularly in plants. More specifically, polynucleotides such as double-stranded RNA triggers and methods of use thereof for modifying the expression of genes in flea beetles.Type: GrantFiled: June 27, 2019Date of Patent: September 21, 2021Assignee: MONSANTO TECHNOLOGY LLCInventors: Michael John Crawford, Brian Donovan Eads
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Patent number: 11118189Abstract: Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.Type: GrantFiled: December 2, 2016Date of Patent: September 14, 2021Assignee: Ceres, Inc.Inventors: Roger I. Pennell, Richard Hamilton, Delin Liang
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Patent number: 11091772Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.Type: GrantFiled: November 22, 2017Date of Patent: August 17, 2021Assignee: BASF Agricultural Solutions Seed US LLCInventors: James Doroghazi, Duane Lehtinen, Elyse Ann Rodgers-Vieira, Jongmin Baek
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Patent number: 11091520Abstract: The present invention is directed to the vegetative insecticidal proteins (Vips) modified to comprise heterologous bacterial carbohydrate binding modules and the methods of use thereof. Expression of modified proteins resulted in variations to activity against lepidopteran pest species of agricultural importance such as Corn earworm and Fall armyworm conveying broad spectrum insect control.Type: GrantFiled: August 7, 2019Date of Patent: August 17, 2021Assignee: Syngenta Participations AGInventor: Joseph M. Watts
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Patent number: 11085052Abstract: Provided herein are plants that reduce growth of a fungal pathogen, increase resistance of the plant to a fungal pathogen, or a combination thereof. The plant includes a polynucleotide that reduces expression of a coding region present in a fungal pathogen, such as Sclerotinia sclerotiorum or Botrytis cinerea. The polynucleotide can be present on the surface of the plant, expressed by a plant, or a combination thereof. Also provided are methods of making and methods of using the plants.Type: GrantFiled: May 3, 2017Date of Patent: August 10, 2021Assignee: University of ManitobaInventors: Steve Whyard, Mark Belmonte
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Patent number: 11085051Abstract: The present invention relates to methods of increasing pathogen resistance in a plant or a part of a plant. In one aspect, the method comprises contacting the plant or the part of the plant with a double-stranded RNA or a small RNA duplex that targets a fungal dicer-like (DCL) gene, wherein the plant or the part of the plant has increased resistance to a fungal pathogen compared to a control plant or control plant part that has not been contacted with the double-stranded RNA or small RNA duplex.Type: GrantFiled: April 27, 2016Date of Patent: August 10, 2021Assignee: The Regents of the University of CaliforniaInventor: Hailing Jin
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Patent number: 11046972Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of insect pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in insect pests, including coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of insect pests, and the plant cells and plants obtained thereby.Type: GrantFiled: May 27, 2016Date of Patent: June 29, 2021Assignees: Dow AgroSciences LLC, Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Kenneth E. Narva, Sarah E. Worden, Meghan Frey, Murugesan Rangasamy, Premchand Gandra, Wendy Lo, Elane Fishilevich, Andreas Vilcinskas, Eileen Knorr
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Patent number: 11046974Abstract: The disclosure presents a platform for discovering novel insecticidal proteins from highly heterogeneous environmental sources. The methodology utilizes metagenomic enrichment procedures and unique genetic amplification techniques, which enables access to a broad class of unknown microbial diversity and their resultant proteome. The disclosed insecticidal protein discovery platform (IPDP) can be computationally driven and is able to integrate molecular biology, automation, and advanced machine learning protocols. The platform will enable researchers to rapidly and accurately access the vast repertoire of untapped insecticidal proteins produced by uncharacterized and complex microbial environmental samples. Also presented herein are a group of newly discovered pore-forming toxins (PFT) from a rare class of insecticidal proteins, which were discovered utilizing the insecticidal protein discovery platform.Type: GrantFiled: September 1, 2020Date of Patent: June 29, 2021Assignee: Zymergen Inc.Inventors: William W. Hwang, Jeffrey Kim, Oliver Liu, Jennifer Shock
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Patent number: 11033622Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor “programmed death 1” (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 as well as the interaction of CTLA4 with CD86 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.Type: GrantFiled: May 25, 2018Date of Patent: June 15, 2021Assignee: Leidos, Inc.Inventors: Gabriel M. Gutierrez, Vinayaka Kotraiah, Timothy W. Phares, James Pannucci
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Patent number: 11028134Abstract: The present invention is directed to the vegetative insecticidal proteins (Vips) modified to comprise heterologous bacterial carbohydrate binding modules and the methods of use thereof. Expression of modified proteins resulted in variations to activity against lepidopteran pest species of agricultural importance such as Corn earworm and Fall armyworm conveying broad spectrum insect control.Type: GrantFiled: August 7, 2019Date of Patent: June 8, 2021Assignee: Syngenta Participations AGInventor: Joseph M. Watts
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Patent number: 11015207Abstract: Provided are pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.Type: GrantFiled: September 24, 2018Date of Patent: May 25, 2021Assignee: The Regents of the University of CaliforniaInventor: Hailing Jin
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Patent number: 11008371Abstract: The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.Type: GrantFiled: September 25, 2017Date of Patent: May 18, 2021Inventors: Andre Roger Abad, Andrew Carl Crow, Brad Poland, Jimei Wang
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Patent number: 10939656Abstract: The invention relates to the novel cotton variety designated 16R228NRB2XF. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 16R228NRB2XF. Also provided by the invention are methods of using cotton variety 16R228NRB2XF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 16R228NRB2XF with itself or another cotton variety and plants and seeds produced by such methods.Type: GrantFiled: December 5, 2018Date of Patent: March 9, 2021Assignee: Monsanto Technology LLCInventors: Vivek Sharma, Robert E. McGowen
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Patent number: 10941398Abstract: The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.Type: GrantFiled: November 28, 2011Date of Patent: March 9, 2021Assignee: Monsanto Technology LLCInventors: Gregory R. Heck, Tichafa R. I. Munyikwa, Jean C. Goley, James K. Roberts, Scott C. Johnson, Ty T. Vaughn
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Patent number: 10941413Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in plants and/or plant cells. This is achieved by increasing the expression of a CASAR protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the order Pucciniales, preferably the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding a CASAR protein.Type: GrantFiled: July 13, 2018Date of Patent: March 9, 2021Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Holger Schultheiss, Nadine Tresch, Ralf Flachmann
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Patent number: 10934330Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.Type: GrantFiled: December 4, 2018Date of Patent: March 2, 2021Assignee: Syngenta Participations AGInventors: Yan Gao, Jared Conville, Jeng Shong Chen
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Patent number: 10932471Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.Type: GrantFiled: April 10, 2018Date of Patent: March 2, 2021Inventors: Denny Joseph Bruck, Frederick C. Burns, II, James Kevin Presnail
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Patent number: 10905127Abstract: The present disclosure provides compositions comprising Corn Rootworm (CRW)-active Methylobacterium sp., methods for controlling CRW, and methods of making the compositions. Also provided are isolated CRW-active Methylobacterium sp.Type: GrantFiled: October 27, 2015Date of Patent: February 2, 2021Assignee: NEWLEAF SYMBIOTICS, INC.Inventors: Marcus Jones, Gregg Bogosian
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Patent number: 10870862Abstract: The invention relates to a method to change the capacity of a plant for adaptation to changes in the zinc concentration in the environment, especially the soil, comprising providing said plant with a nucleotide according to SEQ ID NO:1 or SEQ ID NO: 2 or an ortholog thereof. Such a method is especially useful to decrease Zn deficiency or to (hyper)accumulate Zn in plants for bioremediation or for biofortification. Transgenic plants for these proteins are also disclosed.Type: GrantFiled: October 19, 2018Date of Patent: December 22, 2020Assignee: WAGENINGEN UNIVERSITEITInventors: Ana Gonçalves Leite De Assunçao, Martinus Gerardus Maria Aarts
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Patent number: 10858668Abstract: The present disclosure provides maize plants exhibiting broad spectrum resistance to Northern Leaf Blight (NLB). Maize plants with multiple NLB resistance loci located in cis linkage on chromosome 8 are provided. Compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are further provided.Type: GrantFiled: September 28, 2018Date of Patent: December 8, 2020Assignee: Seminis Vegetable Seeds, Inc.Inventors: Bart Willem Brugmans, Jonathan Tyler Eckard, David Elon Fisher, Tim J. Gustafson, Chad Kramer
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Patent number: 10851386Abstract: System, including methods and compositions, for making and using transgenic plants capable of metabolizing phosphite to reduce competition from weeds. The plants may be transgenically modified to express a phosphite dehydrogenase enzyme capable of catalyzing oxidation of phosphite to phosphate and grown in the presence of sufficient phosphite to selectively promote growth of the plant relative to weeds near the plant.Type: GrantFiled: July 27, 2012Date of Patent: December 1, 2020Assignee: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV)Inventors: Luis Rafael Herrera-Estrella, Damar Lisbeth López-Arredondo
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Patent number: 10837067Abstract: The present disclosure is in the field of plant breeding and disease resistance. The disclosure provides methods for breeding corn plants having late wilt (LW) resistance using marker-assisted selection. The disclosure further provides corn germplasm resistant to LW. The disclosure also provides markers associated with LW resistance loci for introgressing these loci into elite germplasm in a breeding program, thus producing novel LW resistant germplasm.Type: GrantFiled: August 11, 2017Date of Patent: November 17, 2020Assignee: MONSANTO TECHNOLOGY LLCInventors: Rakesh B, Sunil Kumar Biradar, Franck Jean Chopin, Romain Fouquet, Sonali Dilip Gandhi, Erappa Gangappa, Veeresh R P Gowda, Yule Pan, Jean-Luc Pellet, Dharanendra Swamy, Gonzalo Torres, Chongqing Xie
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Patent number: 10829781Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.Type: GrantFiled: May 14, 2018Date of Patent: November 10, 2020Assignee: Monsanto Technology LLCInventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
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Patent number: 10822609Abstract: The present invention relates to the control of infestation of pests by inhibiting or reducing the expression of genes of the family of chitin synthase. The invention further provides methods and compositions for controlling pests by feeding them with one or more double-strand RNA molecules provides by the present invention. The invention further describes a method of obtaining transgenic plants that express double-strand RNA molecules. The present invention is preferably used for cotton-plants.Type: GrantFiled: December 27, 2013Date of Patent: November 3, 2020Assignees: EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA—EMBRAPA, Universidade Federal do Rio Grande do SulInventors: Maria Fátima Grossi de Sá, Alexandre Augusto Pereira Firmino, Maria Cristina Mattar da Silva, Diogo Martins de Sá, Roberta Ramos Coelho, Leonardo Lima Pepino de Macedo, Isabela Tristan Lourenco
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Patent number: 10808261Abstract: The present invention relates to the field of double-stranded RNA (dsRNA)-mediated gene silencing in insect species. More particularly, the present invention relates to genetic constructs designed for the expression of dsRNA corresponding to novel target genes in the insect pest Lymantria dispar, commonly known as the gypsy moth. The present invention also provides methodologies for introducing dsRNA into target insects to induce RNA interference. These constructs are particularly useful in RNAi-mediated control of the gypsy moth.Type: GrantFiled: August 13, 2018Date of Patent: October 20, 2020Assignee: The United States of America, as represented by The Secretary of AgricultureInventors: Dawn E. Gundersen-Rindal, Saikat Kumar B. Ghosh
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Patent number: 10793610Abstract: Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptide sequences having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the pesticidal polypeptides, DNA constructs comprising the nucleic acid molecules, vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the pesticidal polypeptides. Nucleotide sequences encoding the polypeptides provided herein can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest, including microorganisms and plants. The compositions and methods provided herein are useful for the production of organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests.Type: GrantFiled: January 29, 2018Date of Patent: October 6, 2020Assignee: AgBiome, Inc.Inventors: Jessica Parks, Kira Bulazel Roberts, Rebecca E. Thayer
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Patent number: 10781454Abstract: Disclosed herein are viral vectors based on modifications of the Citrus Tristeza virus useful for transfecting citrus trees for beneficial purposes. Included in the disclosure are viral vectors including one or more gene cassettes that encode heterologous polypeptides. The gene cassettes are positioned at desirable locations on the viral genome so as to enable expression while preserving functionality of the virus. Also disclosed are methods of transfecting plants and plants transfected with viral vector embodiments.Type: GrantFiled: May 8, 2018Date of Patent: September 22, 2020Assignee: University of Florida Research Foundation, IncorporatedInventors: William O. Dawson, Svetlana Folimonova, Choaa Amine El Mohtar, Siddarame Gowda, Subhas Hajeri
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Patent number: 10781457Abstract: The disclosure relates to a method for increasing the resistance of a plant to a plant RNA virus, comprising expressing in said plant a mutant protein-only RNase P enzyme lacking a nuclear localization signal domain or an organelle targeting sequence domain, and related compositions.Type: GrantFiled: May 22, 2015Date of Patent: September 22, 2020Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Philippe Giege, Anthony Gobert
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Patent number: 10760094Abstract: The present invention concerns a transgenic plant of the species Solanum tuberosum with a resistance to an oomycete of the genus Phytophthora, transgenic parts of such a plant, a method for its manufacture and to a composition for external application to plants. On the one hand, nucleotide sequences in accordance with SEQ ID NOS: 1-43 are provided from Phytophthora in a host plant-induced gene silencing strategy in potato plants; on the other hand, a fungicide for plant treatment is provided.Type: GrantFiled: July 5, 2018Date of Patent: September 1, 2020Assignee: KWS SAAT SE & CO. KGAAInventors: Jurgen Dietmar Stahl, Nora Temme
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Patent number: 10731225Abstract: This invention relates to polynucleotide sequences encoding genes that can confer resistance to the plant pathogen Colletotrichum, which causes anthracnose stalk rot, leaf blight and top dieback in corn and other cereals. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resistance to the plant pathogen Colletotrichum, and processes of making said plants and seeds. The invention further presents sequences that can be used as molecular markers that in turn can be used to identify the region of interest in corn lines resulting from new crosses and to quickly and efficiently introgress the genes from corn lines carrying said genes into other corn lines that do not carry said genes, in order to make them resistant to Colletotrichum and resistant to stalk rot.Type: GrantFiled: December 14, 2018Date of Patent: August 4, 2020Assignee: E.I. DU PONT DE NEMOURS AND COMPANYInventors: Karen E. Broglie, Karlene H Butler
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Patent number: 10717988Abstract: The invention relates to a Brassica plant in particular a Brassica oleracea plant comprising a genetic determinant, which when homozygously present confers high resistance against Thrips tabaci, and which is as found in plants grown from seeds of which a representative sample is deposited with the NCIMB under NCIMB accession number 41760. Preferably, the plant is homozygous for the genetic determinant and resistant against Thrips tabaci. The genetic determinant in the seeds of NCIMB deposit 41760 is located on chromosome 2 and linked to marker BO00200 (SEQ ID NO: 1) and/or marker BO00277 (SEQ ID NO: 2) and/or BO00602 (SEQ ID NO: 5).Type: GrantFiled: August 11, 2017Date of Patent: July 21, 2020Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventor: Harm Löptien
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Patent number: 10683517Abstract: The subject invention relates in part to the surprising discovery that Cry1Da is active against corn earworm (CEW), Helicoverpa zea (Boddie). Methods for using Cry1Da in transgenic plants to prevent serious crop damage is described. Leaf and silk bioassays using transgenic maize expressing full length, core toxin region or chimeric Cry1Da demonstrated good insect protection against CEW larvae damage.Type: GrantFiled: February 12, 2018Date of Patent: June 16, 2020Assignee: AGRIGENETICS, INC.Inventors: Sek Yee Tan, Joel J. Sheets, Todd Glancy, Aaron T. Woosley, Sarah E. Worden, Diaa Alabed, Stephanie Burton, Karen C. McLaughlin, Kenneth E. Narva, Thomas Meade
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Patent number: 10683516Abstract: Provided herein are Vitis vinifera exhibiting Erysiphe necator resistance. In particular, provided herein are Vitis vinifera having in their genome mildew resistance locus O (MLO) genes, in particular an MLO7 gene and an MLO6 gene, where the MLO7 gene and MLO6 gene have reduced expression and/or function.Type: GrantFiled: July 5, 2016Date of Patent: June 16, 2020Assignee: FONDAZIONE EDMUND MACHInventors: Mickael Malnoy, Stefano Pessina, Riccardo Velasco, Michele Perazzolli, Luisa Lenzi
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Patent number: 10676757Abstract: Insecticidal toxins derived from Bacillus thuringiensis, polynucleotides encoding such toxins, use of such toxins to control plant pests, and transgenic plants that produce, and are protected, by these toxins are described.Type: GrantFiled: August 16, 2016Date of Patent: June 9, 2020Assignee: DOW AGROSCIENCES LLCInventors: Timothy D. Hey, Janna Mai Armstrong, Ted Letherer, Audrey Jane Etter, Meghan L. Frey, Haley Ellis, Kenneth E. Narva, Xiaoping Xu, Krishna M. Madduri, Sek Yee Tan, Premchand Gandra
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Patent number: 10676745Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 19, 2014Date of Patent: June 9, 2020Assignee: Dow AgroSciences LLCInventors: Kenneth E. Narva, Kanika Arora, Muregesan Rangasamy, Balaji Veeramani, Premchand Gandra, Sarah E. Worden, Huarong Li, Andreas Vilcinskas, Eileen Knorr