The Polynucleotide Confers Pathogen Or Pest Resistance Patents (Class 800/279)
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Patent number: 10246722Abstract: Methods of inhibiting plant parasitic nematodes, methods of obtaining transgenic plants useful for inhibiting such nematodes, and transgenic plants that are resistant to plant parasitic nematodes through inhibition of plant nematode CLAVATA3/ESR (CLE) peptide receptor genes are provided. Methods for expressing genes at plant parasitic nematode feeding sites with plant nematode CLE peptide receptor gene promoters are also provided, along with nematode CLE peptide receptor gene promoters that are useful for expressing genes in nematode feeding sites as well as transgenic plants and nematode resistant transgenic plants comprising the promoters.Type: GrantFiled: July 13, 2012Date of Patent: April 2, 2019Assignees: The Curators of the University of Missouri, Cornell University, The United States of America, as Represented by the Secretary of AgricultureInventors: Melissa G. Mitchum, Amy Replogle, Jianying Wang, Xiaohong Wang, Shiyan Chen, Ping Lang
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Patent number: 10232012Abstract: A pH-responsive fusion peptide according to the present disclosure, containing a cell-penetrating peptide exhibiting a positive charge, which contains 2-15 arginine residues, and a ?-sheet-forming segment, experiences structural change depending on pH change. Due to the structural change, the anti-prion activity and cytotoxicity of the fusion peptide can be controlled as desired.Type: GrantFiled: November 30, 2017Date of Patent: March 19, 2019Assignees: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUSInventors: Yong beom Lim, Chong suk Ryou
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Patent number: 10221431Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2-3, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.Type: GrantFiled: August 8, 2014Date of Patent: March 5, 2019Assignee: Athenix Corp.Inventors: Kira Roberts, Kimberly S. Sampson, Duane Lehtinen, Leonardo Magalhaes
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Patent number: 10221429Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:21-74, or the nucleotide sequence set forth in SEQ ID NO: 1-20, as well as variants and fragments thereof.Type: GrantFiled: March 6, 2014Date of Patent: March 5, 2019Assignee: Bayer CropScience LPInventors: Rebecca Thayer, Kimberly S. Sampson, Duane Lehtinen, Cheryl Peters, Kira Roberts, Leonardo Magalhaes, Ethan Dunn
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Patent number: 10196633Abstract: Compositions and methods for controlling pests are disclosed. In particular, methods for modulating the activity of Cry1Ba proteins against lepidopteran or coleopteran pests are provided. Further, mutant Cry1Ba proteins having modulated insecticidal activity compared to native Cry1Ba proteins are disclosed.Type: GrantFiled: December 9, 2015Date of Patent: February 5, 2019Assignee: Syngenta Participations AGInventors: Yan Gao, Jared Conville, Jeng Shong Chen
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Patent number: 10190126Abstract: This application provides and discloses small RNAs and their target genes that are involved in controlling the levels of sucrose, glucose, and fructose and methods of modulating expression or activity of these mi RNAs and target genes. This application further provides transgenic plants, plant parts, e.g., seeds, that have altered expression of these mi RNAs and target genes and have increased levels of sucrose, increased sucrose to glucose ratios, increased sucrose to hexose ratios, altered carbohydrate levels, or increased Brix in fruit from transgenic plants. This application also provides methods of producing and growing transgenic plants or seeds that have increased levels of sucrose, increased sucrose to glucose ratios, increased sucrose to hexose ratios, altered carbohydrate levels, or increased Brix in fruit from transgenic plants.Type: GrantFiled: October 28, 2013Date of Patent: January 29, 2019Assignee: A.B. Seeds Ltd.Inventors: Rudy Maor, Iris Nesher
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Patent number: 10190134Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the expression of a target sequence in the pest. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 6-12, 18-40 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: GrantFiled: March 13, 2014Date of Patent: January 29, 2019Assignee: E I DU PONT DE NEMOURS AND COMPANYInventors: Brian McGonigle, James Kevin Presnail, Navdeep Singh Mutti
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Patent number: 10184130Abstract: Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased resource use efficiency, increased water use efficiency, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.Type: GrantFiled: October 31, 2014Date of Patent: January 22, 2019Assignee: KOCH BIOLOGICAL SOLUTIONS, LLCInventors: Graham J. Hymus, T. Lynne Reuber, Colleen M. Marion, Oliver J. Ratcliffe, Jeffrey M. Libby
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Patent number: 10174340Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.Type: GrantFiled: June 27, 2016Date of Patent: January 8, 2019Assignee: Monsanto Technology LLCInventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
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Patent number: 10174339Abstract: This disclosure relates generally to the field of anti-pathogenic agents, including a modified defensin molecule with anti-pathogen activity. Genetically modified plants and their progeny or parts expressing or containing the modified defensin and anti-pathogen compositions for use in horticulture and agriculture and as animal and human medicaments are also provided.Type: GrantFiled: October 18, 2016Date of Patent: January 8, 2019Assignee: Hexima LimitedInventors: Nicole Van Der Weerden, Marilyn Anne Anderson
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Patent number: 10155960Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.Type: GrantFiled: August 25, 2016Date of Patent: December 18, 2018Assignee: Monsanto Technology LLCInventors: David J. Bowen, Catherine A. Chay, Todd A. Ciche, Uma R. Kesanapalli, Jennifer L. Lutke
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Patent number: 10119148Abstract: The present invention relates to pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.Type: GrantFiled: October 2, 2014Date of Patent: November 6, 2018Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventor: Hailing Jin
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Patent number: 10106810Abstract: The invention relates to a method to change the capacity of a plant for adaptation to changes in the zinc concentration in the environment, especially the soil, comprising providing said plant with a nucleotide according to SEQ ID NO:1 or SEQ ID NO: 2 or an ortholog thereof. Such a method is especially useful to decrease Zn deficiency or to (hyper)accumulate Zn in plants for bioremediation or for biofortification. Transgenic plants for these proteins are also disclosed.Type: GrantFiled: July 16, 2010Date of Patent: October 23, 2018Assignee: WAGENINGEN UNIVERSITEITInventors: Ana Goncalves Leite De Assuncao, Martinus Gerardus Maria Aarts
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Patent number: 10093945Abstract: The present invention relates to the field of double-stranded RNA (dsRNA)-mediated gene silencing in insect species. More particularly, the present invention relates to genetic constructs designed for the expression of dsRNA corresponding to novel target genes in the insect pest Lymantria dispar, commonly known as the gypsy moth. The present invention also provides methodologies for introducing dsRNA into target insects to induce RNA interference. These constructs are particularly useful in RNAi-mediated control of the gypsy moth.Type: GrantFiled: November 13, 2015Date of Patent: October 9, 2018Assignee: The United States of America, as represented by The Secretary of AgricultureInventors: Dawn E. Gundersen-Rindal, Saikat Kumar B. Ghosh
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Patent number: 10093946Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a Bacillus thuringiensis toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:5-26, or the nucleotide sequence set forth in SEQ ID NO: 1-4, as well as variants and fragments thereof.Type: GrantFiled: December 8, 2014Date of Patent: October 9, 2018Assignee: BASF SEInventors: Duane Alan Lehtinen, Kimberly S. Sampson, Kira Roberts, Ethan Dunn
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Patent number: 10053706Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 16, 2015Date of Patent: August 21, 2018Assignees: Dow AgroSciences LLC, The Board of Regents of the University of NebraskaInventors: Blair D. Siegfried, Kenneth E. Narva, Kanika Arora, Sarah E. Worden, Chitvan Khajuria, Elane Fishilevich, Nicholas P. Storer, Meghan Frey, Ronda L. Hamm, Ana Velez
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Patent number: 10047374Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in hemipteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of hemipteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 16, 2015Date of Patent: August 14, 2018Assignees: Dow AgroSciences LLC, The Board of Regents of the University of NebraskaInventors: Blair D. Siegfried, Kenneth E. Narva, Kanika Arora, Sarah E. Worden, Chitvan Khajuria, Elane Fishilevich, Nicholas P. Storer, Meghan Frey, Ronda L. Hamm, Ana Velez
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Patent number: 10041088Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in plants and/or plant cells. This is achieved by increasing the expression of a CASAR protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the order Pucciniales, preferably the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding a CASAR protein.Type: GrantFiled: November 7, 2013Date of Patent: August 7, 2018Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Holger Schultheiss, Nadine Tresch, Ralf Flachmann
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Patent number: 10039258Abstract: The present disclosure provides for unique spinach plants with broad-spectrum resistance to downy mildew and their progeny. Such plants may comprise an introgressed QTL associated with the broad-spectrum resistance to downy mildew. In certain aspects, compositions, including distinct polymorphic molecular markers, and methods for producing, using, identifying, selecting, and the like of plants or germplasm with resistance to downy mildew are provided.Type: GrantFiled: October 8, 2014Date of Patent: August 7, 2018Assignee: Seminis Vegetable Seeds, Inc.Inventors: Bart Willem Brugmans, Eduardo López Fernandez, Inge Weber
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Patent number: 10023876Abstract: Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide sequences encoding the pesticidal polypeptide can be used to transform various prokaryotic and eukaryotic organisms, which organisms can be used to produce the pesticidal polypeptides. The recombinant organisms and/or the polypeptides produced by the recombinant organisms can be used to control pests in various environments.Type: GrantFiled: January 23, 2013Date of Patent: July 17, 2018Inventors: Mikyong Lee, Jeng Shong Chen, Cheryl Marie De Fontes, Jared Conville, Narendra Palekar
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Patent number: 10023877Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 12, 2014Date of Patent: July 17, 2018Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A. Patten, Takashi Yamamoto
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Patent number: 10017747Abstract: Disclosed herein are viral vectors based on modifications of the Citrus Tristeza virus useful for transfecting citrus trees for beneficial purposes. Included in the disclosure are viral vectors including one or more gene cassettes that encode heterologous polypeptides. The gene cassettes are positioned at desirable locations on the viral genome so as to enable expression while preserving functionality of the virus. Also disclosed are methods of transfecting plants and plants transfected with viral vector embodiments.Type: GrantFiled: May 5, 2014Date of Patent: July 10, 2018Assignee: University of Florida Research Foundation, Inc.Inventors: William O. Dawson, Svetlana Folimonova, Choaa Amine El Mohtar, Siddarame Gowda, Subhas Hajeri
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Patent number: 9994920Abstract: Various methods and compositions are provided for identifying and/or selecting soybean plants or soybean germplasm with resistance or improved resistance to soybean cyst nematode. In certain embodiments, the method comprises detecting at least one marker locus that is associated with resistance to soybean cyst nematode. In other embodiments, the method further comprises detecting at least one marker profile or haplotype associated with resistance to soybean cyst nematode. In further embodiments, the method comprises crossing a selected soybean plant with a second soybean plant. Further provided are markers, primers, probes and kits useful for identifying and/or selecting soybean plants or soybean germplasm with resistance or improved resistance to soybean cyst nematode.Type: GrantFiled: January 20, 2016Date of Patent: June 12, 2018Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Joshua M Shendelman, John B Woodward, Meizhu Yang
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Patent number: 9994844Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 16, 2015Date of Patent: June 12, 2018Assignees: Dow AgroSciences LLC, The Board of Regents of the University of NebraskaInventors: Blair D. Siegfried, Kenneth E. Narva, Kanika Arora, Sarah E. Worden, Chitvan Khajuria, Elane Fishilevich, Nicholas P. Storer, Meghan Frey, Ronda L. Hamm, Ana M. Velez
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Patent number: 9988642Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.Type: GrantFiled: May 15, 2015Date of Patent: June 5, 2018Assignee: Monsanto Technology LLCInventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
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Patent number: 9957524Abstract: The invention generally relates to the field of insect inhibitory toxin proteins. A novel class of proteins exhibiting insect inhibitory activity against agriculturally relevant pests of crop plants and seeds are disclosed. Insecticidal activity is particularly effective against the Coleopteran order of insect pests. Plants, plant parts, and seed are provided containing a polynucleotide construct encoding one or more of the toxin proteins disclosed herein. The proteins are referred to herein variously as the TIC2463-related toxin protein class or family, the TIC2463-related toxin proteins, the TIC2463-related protein genus, toxin proteins related to the TIC2463 toxin protein, proteins related to TIC2463, TIC2463-related toxin polypeptides, TIC2463-related pesticidal proteins, and the like.Type: GrantFiled: March 27, 2015Date of Patent: May 1, 2018Assignee: Monsanto Technology LLCInventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Xiaoran Fu, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Daqi Tu, Andrew M. Wollacott, Yong Yin
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Patent number: 9957523Abstract: The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for making transgenic plants that express the double stranded RNA molecules, as well as pesticidal agents and commodity products produced by the inventive plants.Type: GrantFiled: July 7, 2014Date of Patent: May 1, 2018Assignee: Devgen NVInventors: Romaan Raemaekers, Pascale Feldmann, Irene Nooren, Geert Plaetinck, Frederic Pecqueur, Els Van Bleu, Thierry Bogaert
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Patent number: 9957522Abstract: The present invention relates to a method of increasing resistance against fungal pathogens of the family Phacopsoraceae in plants and/or plant cells. This is achieved by increasing the expression of a CASAR protein or fragment thereof in a plant, plant part and/or plant cell in comparison to wild type plants, wild type plant parts and/or wild type plant cells. Furthermore, the invention relates to transgenic plants, plant parts, and/or plant cells having an increased resistance against fungal pathogens, in particular, pathogens of the family Phacopsoraceae, and to recombinant expression vectors comprising a sequence that is identical or homologous to a sequence encoding a CASAR protein.Type: GrantFiled: November 7, 2013Date of Patent: May 1, 2018Assignee: BASF PLANT SCIENCE COMPANY GMBHInventors: Holger Schultheiss, Nadine Tresch, Ralf Flachmann
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Patent number: 9944948Abstract: The present invention relates to the prevention and/or control of infestation by insect pest species. In particular, the invention relates to down-regulation of expression of target genes in insect pests using interfering ribonucleic acid (RNA) molecules. Also described are transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species. Compositions containing the interfering RNAs of the invention are also provided.Type: GrantFiled: October 27, 2011Date of Patent: April 17, 2018Assignee: Devgen NVInventors: Thierry Bogaert, Romaan Raemaekers, Yann Naudet
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Patent number: 9932603Abstract: The present invention is related to a method for conveying viral resistance or tolerance to one or more virus(es), in particular to beet mild yellowing virus (BMYV) and to beet necrotic yellow vein virus (BNYVV) or to BMYV alone in a plant, in particular in a sugar beet plant. Furthermore, the present invention relates to the virus resistant or -tolerant plant obtained according to this method, as well as to seeds and progeny derived therefrom.Type: GrantFiled: June 15, 2012Date of Patent: April 3, 2018Assignee: SESVANDERHAVE NVInventors: Elodie Klein, Véronique Graff, David Gilmer, Véronique Brault, Guy Weyens, Marc Lefebvre
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Patent number: 9932575Abstract: The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides. The scaffolds are particularly well suited for constructing libraries, e.g., in phage display or related systems. The invention also relates to various uses of the scaffolds, including in therapy, diagnosis, environmental and security monitoring, synthetic biology and research, and to cells and cell cultures expressing the scaffold proteins.Type: GrantFiled: February 14, 2014Date of Patent: April 3, 2018Assignee: University of LeedsInventors: Michael McPherson, Darren Tomlinson
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Patent number: 9879277Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 13, 2014Date of Patent: January 30, 2018Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Andre R. Abad, Zhenglin Hou, Lu Liu, Brad Poland, Ute Schellenberger, Ingrid Udranszky, Jimei Wang, Jun-Zhi Wei, Thomas C. Wolfe, Weiping Xie, Lan Zhou, Genhai Zhu
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Patent number: 9845479Abstract: The present invention relates to genetic control of infestation by insect pest species, particularly prevention and/or control of pest infestation of plants, using interfering ribonucleic acid (RNA) molecules. The invention provides transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species.Type: GrantFiled: May 2, 2012Date of Patent: December 19, 2017Assignee: Devgen NVInventors: Myriam Beghyn, Thierry Andre Olivier Eddy Bogaert, Pascale Feldmann, Romaan Raemaekers
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Patent number: 9834785Abstract: A family 1 cellulose-binding-domain (CBD) encoding gene from Phytophthora infestans was used to develop transgenic Bintje potato plants. Tests with detached leaflets showed no evidence of increased or decreased resistance to P. infestans, in comparison with the susceptible Bintje controls. Changes in plant morphology were most evident in the CBD1 multicopy transgenics. Plant height increases were evident in the later growth stages, along with earlier flowering and the ability to produce seed balls. While Bintje control plants are male and female sterile, the multicopy transgenics were male sterile and female fertile. Crosses made into Bintje demonstrated the ability to transfer P. infestans targeted R genes, as well as genes responsible for color and tuber shape, into Bintje germplasm. Selection for the absence of the CBD1 transgene should allow for immediate use of the material.Type: GrantFiled: August 26, 2015Date of Patent: December 5, 2017Assignee: The United States of America, as represented by the Secretary of AgricultureInventors: Richard W. Jones, Frances G. Perez
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Patent number: 9803204Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: May 4, 2015Date of Patent: October 31, 2017Inventors: Kenneth E. Narva, Huarong Li, Chaoxian Geng, Ignacio Larrinua, Monica Britt-Olson, Navin Elango, Mathew J. Henry
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Patent number: 9770035Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: October 5, 2012Date of Patent: September 26, 2017Assignee: Dow AgroSciences LLCInventors: Kenneth E. Narva, Huarong Li, Chaoxian Geng, Ignacio Larrinua, Monica Britt Olson, Navin Elango
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Patent number: 9695439Abstract: The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.Type: GrantFiled: April 2, 2013Date of Patent: July 4, 2017Assignee: Monsanto Technology LLCInventors: James A. Baum, Claire A. CaJacob, Pascale Feldmann, Gregory R. Heck, Irene Maria Antonia Nooren, Geert Plaetinck, Ty T. Vaughn, Wendy Maddelein
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Patent number: 9695436Abstract: Methods are provided for enhancing yield and nitrogen use efficiency in plants, and to methods of increasing biomass and seed yield in plants grown under nitrogen limiting conditions using variants of enzymes involved in nitrogen assimilation or metabolism from non-plant organisms.Type: GrantFiled: March 4, 2014Date of Patent: July 4, 2017Assignee: BAYER CROPSCIENCE LPInventors: Chandra McAllister, Perrin Beatty, Jayne D'Entremont, Allen Good
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Patent number: 9688984Abstract: Methods and compositions that affect grain shape, width, and yield in rice are disclosed. Methods of transgenic modulation and marker-assisted breeding methods improve grain length to width ratio and grain yield in rice. Down-regulation of OsSPL16 in rice resulted in increased grain quality.Type: GrantFiled: September 19, 2012Date of Patent: June 27, 2017Assignee: INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGYInventors: Xiangdong Fu, Shaokui Wang, Kun Wu, Guiquan Zhang, Ruizhen Zeng
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Patent number: 9681621Abstract: A novel maize variety designated PH1DG1 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1DG1 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1DG1 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1DG1 or a locus conversion of PH1DG1 with another maize variety.Type: GrantFiled: February 11, 2015Date of Patent: June 20, 2017Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventor: Gustavo Marcelo Garcia
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Patent number: 9683242Abstract: The invention provides specific transgenic soybean plants, plant material and seeds, characterized in that these products harbor a stack of specific transformation events at specific locations in the soybean genome. Tools are also provided which allow rapid and unequivocal identification of these events in biological samples.Type: GrantFiled: November 23, 2010Date of Patent: June 20, 2017Assignees: M.S. Technologies, LLC, Bayer CropScience N.V.Inventors: Justin Thomas Mason, Leslie James Lettow, Mark Alan Eby, William H. Eby, Gunter Welz, Steven Verhaeghe, Marc De Beuckeleer, Veerle Habex, Jean-Marc Ferrulo
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Patent number: 9670465Abstract: An object of the present invention is to provide a novel method of controlling TYLCV whereby the infection cycle of TYLCV can be broken. The present invention provides a novel virus that is not transmitted by an insect vector as a tomato yellow leaf curl virus. The present invention also provides a method of controlling a tomato yellow leaf curl disease and a method of preventing transmission of a yellow leaf curl virus by using a tomato yellow leaf curl virus not transmitted by an insect vector.Type: GrantFiled: February 3, 2012Date of Patent: June 6, 2017Assignee: KIKKOMAN CORPORATIONInventors: Hiroki Atarashi, Toshiro Inoue, Haruki Sayama, Hisashi Nishigawa, Tamotsu Murai, Tomohide Natsuaki
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Patent number: 9663794Abstract: Provided in the present invention are a separated endogenous rice gene resistant to high temperature (hereinafter referred to as the OsZFP gene for short) and a polypeptide encoded thereby, optimizing rice cells comprising the heat-resistant gene of the present invention or the polypeptide encoded thereby, and the plant cell preparation method thereof. Further provided are new methods and technologies for breeding new varieties of heat-resistant crops, comprising the related regulatory sequence for heat-resistance and a closely linked molecular marker denoting the heat-resistant gene and the sequence thereof.Type: GrantFiled: June 4, 2015Date of Patent: May 30, 2017Assignees: Zhejiang University, Rice Research Institute, Guangdong Academy of Agricultural SciencesInventors: Jumin Tu, Xuhua Zhong, Jianping Liu, Nongrong Huang
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Patent number: 9655313Abstract: A novel maize variety designated PH1KKG and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KKG with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1KKG through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1KKG or a locus conversion of PH1KKG with another maize variety.Type: GrantFiled: February 11, 2015Date of Patent: May 23, 2017Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventor: Susanne Groh
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Patent number: 9650647Abstract: The present invention provides nucleic acids and methods for conferring resistance to bacterial disease in plants. The present invention also provides promoters and promoter sequences useful for controlling expression in transgenic plants.Type: GrantFiled: September 6, 2010Date of Patent: May 16, 2017Assignee: Temasek Life Sciences Laboratory LimitedInventors: Zhong Chao Yin, Ke Yu Gu, Dong Sheng Tian
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Patent number: 9635825Abstract: The present invention provides an inbred corn line designated ID6461, methods for producing a corn plant by crossing plants of the inbred line ID6461 with plants of another corn plant. The invention further encompasses all parts of inbred corn line ID6461, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line ID6461, and plants produced according to these methods.Type: GrantFiled: November 11, 2015Date of Patent: May 2, 2017Assignee: Syngenta Participations AGInventor: Mohammed Ahmed
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Patent number: 9631200Abstract: The invention relates to a pathogen-inducible synthetic promoter which is suitable for regulating the transcription of a nucleic acid, and includes a minimal promoter, characterized in that the minimal promoter includes a sequence motif a) dbrmwa or b) twcccmt which is disposed downstream from a TATA region and in front of a transcription starting point which is located on the minimal promoter and at which transcription of the nucleic acid to be regulated starts.Type: GrantFiled: November 18, 2014Date of Patent: April 25, 2017Assignee: KWS SAAT SEInventor: Klaus Schmidt
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Patent number: 9617559Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Spodoptera frugiperda. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.Type: GrantFiled: September 30, 2014Date of Patent: April 11, 2017Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: Rafael Herrmann, Michael Lassner, Albert L. Lu, Mark Edward Nelson, James Kevin Presnail, Janet A. Rice
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Patent number: 9617553Abstract: The invention provides recombinant DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising a recombinant DNA molecule comprising a DNA molecule operably linked to a heterologous transcribable DNA molecule, as well as methods of their use.Type: GrantFiled: March 12, 2014Date of Patent: April 11, 2017Assignee: Monsanto Technology LLCInventors: Stanislaw Flasinski, Jun Zhang, Suling Zhao
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Patent number: 9605271Abstract: The present invention relates to plants that have been transformed so as to have both disease resistance and acceptable agronomic traits. More specifically, the present invention relates to transgenic plants that have acquired disease resistance through expression in the plants of a polynucleotide encoding the transcription factor WRKY45 in an infection-responsive manner, and methods for generating the transgenic plants.Type: GrantFiled: January 23, 2013Date of Patent: March 28, 2017Assignee: National Institute of Agrobiological SciencesInventors: Hiroshi Takatsuji, Shingo Goto