Chromatography Patents (Class 95/82)
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Patent number: 12222338Abstract: A gas analyzer includes a self-contained pressure module that at least partly encloses a tube for a gas, wherein a pressure module is equipped with a sensor and a valve, the sensor and the valve are operable through a master control circuit that is accommodated in a self-contained control enclosure outside of the pressure module, separate from the valve and the sensor.Type: GrantFiled: August 31, 2022Date of Patent: February 11, 2025Assignee: GAS CHROMATOGRAPHY SYSTEMS MAXUM GMBHInventors: Glen Eugene Schmidt, Thomas Neuhauser
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Patent number: 12186458Abstract: Various embodiments of the present invention are directed towards a device and method relating to heating a sample. For example, a device includes a housing to support a sample including a trace of an explosive. A power supply is coupled to the housing to provide power to a heating element coupled to the housing. The heating element is configured to heat the sample to generate a vapor of at least one ingredient of the trace.Type: GrantFiled: March 28, 2019Date of Patent: January 7, 2025Assignee: The Government of the United States of America, represented by the Secretary of Homeland SecurityInventor: Inho Cho
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Patent number: 12178598Abstract: A therapy system for treating a tissue site with negative-pressure therapy and/or fluid instillation therapy in response to information received from a diagnostic module is described. The therapy system may include a dressing, a negative-pressure source, a container, and a diagnostic module. The dressing be placed on the tissue site, and the negative-pressure source may be fluidly coupled to the dressing. The container may be fluidly coupled to the dressing and to the negative-pressure source to receive fluid from the tissue site. The diagnostic module may be exposed to gas associated with the fluid from the tissue site. The diagnostic module may comprise a sensor configured to detect a condition of the tissue site and to generate an output based on the detected condition. The sensor may be configured to detect a volatile organic compound. The diagnostic module may be positioned on the container.Type: GrantFiled: August 3, 2020Date of Patent: December 31, 2024Assignee: Solventum Intellectual Properties CompanyInventors: Christopher Brian Locke, Richard Daniel John Coulthard, Timothy Mark Robinson
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Patent number: 12158454Abstract: A hybrid trap including a replaceable open-tubular capillary trap followed by a packed trap is used to collect, preconcentrate, and recover a sample, such as VOCs and SVOCs found in air. The capillary stage prevents losses and carryover of the heavy fraction and can also collect the particles in air that contain the heavier SVOCs, also preventing them from reaching the packed stage. The packed stage traps lighter organic compounds that are not as prone to carryover due to channeling. The capillary and packed traps together provide quantitative recovery of compounds boiling from as low as ?50° C. to as high as 600° C. The sample can be directly desorbed onto the GC column, which avoids losses and contamination caused by other approaches that thermally desorb samples through transfer lines and rotary valves more remote to the GC oven.Type: GrantFiled: July 30, 2019Date of Patent: December 3, 2024Assignee: Entech Instruments Inc.Inventor: Daniel B. Cardin
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Patent number: 12157088Abstract: A service system for gas compartments with a gas treatment device for treating a gas present in at least one gas compartment, at least one sensor device for monitoring at least one gas property of the gas, at least one connection coupled to the gas treatment device and the at least one sensor device, which connection is intended for coupling to the gas compartment, at least one conveying device for conveying a gas from the gas compartment into the gas treatment device and from the gas treatment device at least indirectly back into the gas compartment, and at least one control unit which is connected at least to the sensor device and monitors and controls at least the conveying device and/or the gas treatment device.Type: GrantFiled: December 14, 2020Date of Patent: December 3, 2024Assignees: Wika Alexander Wiegand SE & Co. KG, Westnetz GmbHInventors: Daniel Fuchs, Klaus Franz, Dominik Huller, Christoph Rezun, Thomas Saewe
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Patent number: 12055528Abstract: A disclosed micro-separator for gas chromatography includes a base substrate having a trench, a channel column disposed in the trench, and a cover member combined with the base substrate and covering the channel column. The channel column includes a stationary phase having pores ordered and three-dimensionally connected to each other.Type: GrantFiled: October 2, 2019Date of Patent: August 6, 2024Assignee: Korea Advanced Institute of Science and TechnologyInventors: Seokwoo Jeon, Youngsuk Shim, Donghwi Cho, Jade Nadine Ang
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Patent number: 11839852Abstract: Systems and methods for efficient, effective, and safe separation and isolation of multiple isotopes (e.g., Mo, Zr, Ba, Sr, Te, and lanthanide isotopes) from fission products includes use of a plurality of chromatography columns, each containing a chromatographic resin formulated to target one or more particular isotopes. The system is operable in a “series” configuration to load the multiple columns by a single pass of the sample. Then, the system may be transitioned (e.g., using valves) to a “parallel” configuration in which multiple columns of the system may be operated simultaneously to elute targeted isotopes. Additional parallel operations of the columns, using different eluent compositions, may be used to elute different targeted isotopes. The system may be reconditioned in preparation for a subsequent sample.Type: GrantFiled: January 21, 2021Date of Patent: December 12, 2023Assignee: Battelle Energy Alliance, LLCInventors: Mathew S. Snow, Jessica L. Ward
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Patent number: 11808742Abstract: A multi-dimensional liquid chromatography system includes first and second liquid chromatography systems. The first system is configured for providing a first chromatographic separation of a sample fluid comprised in a first mobile phase and to provide a first effluent including at least a portion of the separated sample fluid. The second system is configured for providing a second chromatographic separation of at least a portion of the first effluent comprised in a second mobile phase. A control unit is configured to operate the first liquid chromatography system by maintaining a first flow rate of the first mobile phase substantially constant during the first chromatographic separation, and to operate the second liquid chromatography system during the second chromatographic separation according to a control value different from the second flow rate, so that a variation in the control value can lead to a variation in the second flow rate.Type: GrantFiled: August 26, 2021Date of Patent: November 7, 2023Assignee: Agilent Technologies, Inc.Inventors: Konstantin Shoykhet, Stephan Buckenmaier
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Patent number: 11779916Abstract: A thermo-gravimetric analysis system includes a chamber having an interior; and a sample crucible connected to and inside of the chamber, the sample crucible configured to hold a sample material. The system further includes a reference crucible connected to and inside of the chamber; and a metal organic framework (MOF) crucible connected to and inside of the chamber, separate from the sample crucible, the MOF crucible including an MOF material.Type: GrantFiled: September 14, 2021Date of Patent: October 10, 2023Assignee: International Business Machines CorporationInventors: Eric J. Campbell, Sarah K. Czaplewski-Campbell, Brandon M. Kobilka, Scott B. King
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Patent number: 11754583Abstract: Apparatuses and methods for generating trace vapors are provided. The apparatus includes a controller and an oven. The controller includes: a processor, a memory storing at least one control program, a clean solution supply port constructed to output a clean solution, an analyte solution supply port constructed to output an analyte solution, a carrier gas inlet port constructed to receive a carrier gas, and a plurality of carrier gas supply controllers constructed to output the carrier gas.Type: GrantFiled: February 14, 2019Date of Patent: September 12, 2023Assignee: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Greg Collins, Susan Rose-Pehrsson, Michael Malito, Braden C. Giordano, Adam L. Lubrano, Mark H. Hammond, Cy Tamanaha
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Patent number: 11674892Abstract: A Discrete Sample Introduction Module (DSIM) apparatus includes an internal tubing system to receive into the DSIM apparatus a discrete gas sample having a received concentration. A plurality of valves selectively partitions the internal tubing system to form a plurality of loops corresponding to a plurality of loop volumes to contain the discrete gas sample. The plurality of loop volumes receives a carrier gas to dilute the discrete gas sample to a plurality of preselected dilutions. The DSIM apparatus circulates a given one of the plurality of preselected dilutions for analysis by a spectrometer coupled to the DSIM apparatus.Type: GrantFiled: September 14, 2020Date of Patent: June 13, 2023Assignee: U.S. Geological SurveyInventors: John William Pohlman, Emile Marcel Bergeron, Michael Andrew Casso
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Patent number: 11567092Abstract: A system for detecting mold includes a housing defining a chamber and an opening through a surface. The system includes a movable grate for selectively covering the opening. The system includes a substrate treated to promote mold growth. The system includes a mechanism for moving the substrate to move previously unexposed portions into the chamber. The system includes a thermal control system to maintain predetermined environmental conditions in the chamber. The system includes a sensor configured to detect mold growth in the chamber. The system includes a mold suppressor to kill mold in the chamber when activated. The system includes a controller to coordinate operation of the components to detect mold growth in an environment.Type: GrantFiled: December 12, 2019Date of Patent: January 31, 2023Assignee: Robert Bosch GmbHInventors: Seow Yuen Yee, Franz Laermer, Christian Peters, Ning Wang, Thomas Rocznik
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Patent number: 11557462Abstract: A process chamber, such as for semiconductor processing equipment, is connected with a recovery unit. The recovery unit includes a first storage tank for buffer gas and a second storage tank for rare gas. Both storage tanks are connected with a column in the recovery unit. The recovery unit and process chamber can operate as a closed system. The rare gas can be transported at a variable flow rate while separation in the recovery unit operates at a constant flow condition.Type: GrantFiled: March 10, 2020Date of Patent: January 17, 2023Assignee: KLA CORPORATIONInventors: Chao Chang, Michael Friedmann
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Patent number: 11536703Abstract: Pressure-controlled splitting can be used to inject a chemical sample from an injection source to a detector (e.g., a mass spectrometer) for chemical analysis (e.g., gas chromatography or gas chromatography-mass spectrometry) with reduced peak widths. For example, the sample is first transferred to a first compression volume; then pressure in the system is increased to compress the sample to split it between a second compression volume and a column. The fraction of the sample split to the column can have reduced peak widths compared to the peak widths prior to compression and splitting yet can maintain the same peak height to preserve high sensitivity for trace level analysis. This portion of the sample can traverse the column and elute to the detector for analysis with reduced chemical noise. Faster injection rates can allow faster analysis times, as less separation of chemicals is needed before the sample reaches the detector.Type: GrantFiled: October 24, 2019Date of Patent: December 27, 2022Assignee: Entech Instruments Inc.Inventor: Daniel B. Cardin
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Patent number: 11493489Abstract: The present invention relates to a liquid chromatography system (90) configured to operate with at least one column and configured for purification of a sample comprising a target product using a predefined process. The liquid chromatography system comprises a controller (91) configured to: control the operation of the chromatography system to run the predefined process; retrieve column data accessible from a data storage, the column data being specific to each column; and adapt at least one process parameter of the predefined process for each column based on column data. Whereby the predefined process is adapted to each column to obtain the target product and maintain the performance of the liquid chromatography system.Type: GrantFiled: February 20, 2019Date of Patent: November 8, 2022Assignee: Cytiva Sweden ABInventors: Jens Widehammar, Key Hyckenberg, Orjan Grelsson, Lars Mattsson, Kjell Karlsson
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Patent number: 11092576Abstract: The present invention contemplates a variety of improved techniques including an injection module pairable with an injection port of a gas chromatography device. The injection module can include a cylindrical body, a cap with permeable membrane, a first reservoir for a sample, and a second reservoir for a volume of solvent. An internal membrane can be disposed between the first reservoir and the second reservoir. The injection module can include a circular plunger creating a seal with an inner surface of the cylindrical body of the injection module and configured to expel the sample and solvent by gliding along the inner surface of the cylindrical body. A server can monitor analytes detected by the gas chromatography device and generate recommendations for a user of the gas chromatography device.Type: GrantFiled: March 28, 2019Date of Patent: August 17, 2021Assignee: VORGA CORP.Inventors: Cathie Condron, Justin Chen
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Patent number: 11020687Abstract: Methods for transferring a separation procedure from a first chromatographic system to a second one are disclosed that involve substantially matching a pressure profile. In some such methods, a length, an area, and a particle size of a first column in the first system and a flow rate in the first separation procedure are identifiable. Some such methods also involve selecting a combination of a length, an area, and a particle size of a second column in the second system and a flow rate for the second separation procedure. These methods may involve calculating a target length, a target area, or a target particle size for the second column in the second system or a target flow rate for the second separation procedure.Type: GrantFiled: April 9, 2018Date of Patent: June 1, 2021Assignee: Waters Technologies CorporationInventors: Jason F. Hill, Michael O. Fogwill, Joseph D. Michienzi, Joshua A. Shreve, Abhijit Tarafder
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Patent number: 10994222Abstract: A pre-heater assembly for pre-heating a fluid, in particular in a fluid separation apparatus, wherein the pre-heater assembly comprises a capillary having a lumen and being configured for conducting the fluid, and a thermal coupling body contacting at least part of the capillary, having a value of thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source is supplied to the capillary via at least part of the thermal coupling body.Type: GrantFiled: October 3, 2018Date of Patent: May 4, 2021Assignee: Agilent Technologies, Inc.Inventors: Ansgar Waldbaur, Armin Steinke
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Patent number: 10814251Abstract: Processing liquid is stored by a supply tank. The dissolved oxygen concentration of the processing liquid is measured. The dissolved oxygen concentration of the processing liquid in the supply tank is adjusted by supplying concentration adjusting gas having a concentration of inert gas higher than that of air into the supply tank in accordance with the dissolved oxygen concentration of the processing liquid measured. The processing liquid in the supply tank is supplied to a substrate. The processing liquid that has been supplied to the substrate is collected to the supply tank. Unnecessary gas that is a gas other than the concentration adjusting gas and dissolved in the processing liquid during the processing of the substrate is decreased from the processing liquid before the processing liquid is collected to the supply tank.Type: GrantFiled: January 29, 2019Date of Patent: October 27, 2020Assignee: SCREEN Holdings Co., Ltd.Inventor: Sei Negoro
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Patent number: 10773203Abstract: A xenon capture system that reduces the concentration of xenon in a carrier gas is disclosed. An example xenon capture system includes a carrier gas with a first concentration of xenon that flows through an intake into a chamber. Within the chamber is a reaction area that has at least one peripheral sidewall. The reaction area operates at a predetermined temperature, flow rate, and low pressure. Within the reaction area is at least one xenon capture mechanism that is at least partially formed of a transition metal. When the carrier gas is exposed to the xenon capture mechanism, the xenon capture mechanism adsorbs xenon from the carrier gas. The carrier gas, with a second concentration of xenon, exits the chamber through the exhaust outlet.Type: GrantFiled: September 27, 2017Date of Patent: September 15, 2020Assignee: U.S. Department of EnergyInventors: Catherine Riddle, Dawn M. Scates, Troy G. Garn, Matthew G. Watrous
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Patent number: 9207218Abstract: There is provided a capillary column comprising a flat cross section and a desired theoretical plate number and having both high resolution and high sample load capacity. The capillary column 1 comprising a stationary phase on an inactivated inner surface, which is used in gas chromatography, comprises a narrow part 3 formed in a central part of a cross section of internal space and a bulge part 4 formed on each of both sides of the narrow part 3.Type: GrantFiled: December 17, 2013Date of Patent: December 8, 2015Assignee: FRONTIER LABORATORIES LTD.Inventors: Chuichi Watanabe, Koichi Ito, Atsushi Watanabe
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Patent number: 8968560Abstract: Methods and related apparatuses and mixtures are described for chromatographic analysis. The described system includes a pressurized source of a mobile phase and a flow path in fluid communication with the pressurized source such that the mobile phase flows through the flow path. The system also includes an injector in fluid communication with the flow path and downstream of the pressurized source, the injector being configured to inject a sample into the flow path. A first column located downstream of the injector, contains a stationary phase, and forms part of the flow path. A first detector is positioned to detect properties of fluid in the flow path at a location downstream of the injector and upstream from the first column. A second detector is positioned to detect properties of fluid in the flow path at a location downstream of the first column.Type: GrantFiled: December 6, 2007Date of Patent: March 3, 2015Assignee: Schlumberger Technology CorporationInventor: William H. Steinecker
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Patent number: 8853286Abstract: The present invention is directed to compositions useful for use in separators for use in lithium ion batteries, and membranes, separators, and devices derived therefrom.Type: GrantFiled: September 12, 2013Date of Patent: October 7, 2014Assignees: Drexel University, The Trustees Of The University Of PennsylvaniaInventors: Yossef A. Elabd, Karen I. Winey, Yuesheng Ye, Jae-Hong Choi, Tsen-Shan Sharon Sharick
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Patent number: 8778059Abstract: Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.Type: GrantFiled: December 3, 2007Date of Patent: July 15, 2014Assignee: Schlumberger Technology CorporationInventors: William H. Steinecker, Jagdish Shah, Oleg Zhdaneev, Gordon R. Lambertus, Hua Chen
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Patent number: 8721768Abstract: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device. The microfluidic device can be fluidically coupled to a switching valve to provide for selective control of fluid flow in the chromatography system. In some examples, the microfluidic device may include a charging chamber, a bypass restrictor or other features that can provide for added control of the fluid flow in the system. Methods of using the devices and methods of calculating lengths and diameters to provide a desired flow rate are also described.Type: GrantFiled: October 22, 2012Date of Patent: May 13, 2014Assignee: PerkinElmer Health Sciences, Inc.Inventor: Andrew Tipler
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Patent number: 8591630Abstract: In a fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a standard gas chromatograph oven, which may serve as a heated transfer line to a flexible column that enters the resistively heated metal tube from its injector and exits into its detector. The fast GC device enables less than one minute full range temperature programming and cooling back analysis cycle time. The fast GC according to one embodiment is combined with mass spectrometry with supersonic molecular beams for the provision of fast analysis cycle time together with highly informative mass spectral information for improved sample analysis and identification.Type: GrantFiled: October 6, 2010Date of Patent: November 26, 2013Inventors: Aviv Amirav, Alexander B. Fialkov
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Patent number: 8562837Abstract: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device and that implement one or more methods to direct sample to a desired fluid flow path. The methods can be used to backflush a sample to a desired fluid flow path to select certain analytes within a sample.Type: GrantFiled: September 21, 2011Date of Patent: October 22, 2013Assignee: PerkinElmer Health Sciences, Inc.Inventor: Andrew Tipler
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Patent number: 8506801Abstract: A device for capillary chromatography comprising at least one first receiving space arranged in a circuit board and of a form such that the first receiving space is suitable for at least partially receiving a coiled part of a capillary separation column. Also a method for manufacturing such a device. Using such a device and method the greatest possible advantage can be gained from both miniaturized and integrated gas chromatographs (minimal dead volumes; integration options; small thermal masses and rapid temperature regulation; low cost price; small dimensions, weight and energy consumption; portable and flexible in use) and from the use of a usual capillary separation column (very good separation; high precision and reproducibility). The capillary separation column can herein be heated uniformly, rapidly and accurately.Type: GrantFiled: February 1, 2008Date of Patent: August 13, 2013Assignee: Concept to Volume B.V.Inventors: Gert-Jan Burger, Anne Freerk De Jager, Harm Jan Van Weerden
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Publication number: 20130192463Abstract: Embodiments of the present disclosure provide for collection devices, methods of making collection devices, methods of collecting gases and aerosol particles, and the like.Type: ApplicationFiled: October 17, 2011Publication date: August 1, 2013Inventors: Chang-Yu Wu, Yu-Mei Hsu, Alex Theodore, Lin Shou, Danielle Lyon Hall
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Patent number: 8475568Abstract: This invention relates to a process for the enrichment of isotopes by chromatography on a saturated stationary phase. The process provides a more efficient method than the existing methods.Type: GrantFiled: October 28, 2008Date of Patent: July 2, 2013Assignee: Isosilicon ASInventors: Pierre Hilaireau, Wieslaw Majewski
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Publication number: 20130145933Abstract: An apparatus for separation of gases from ambient air that has at least one separation column containing an adsorbent with an inlet at a first end and an outlet at a second end, a buffer column containing an adsorbent and having a single inlet at a first end, a vacuum pump, and a valve system that connects the vacuum pump to the outlet at the first end of the separation column, and that connects the outlet at the second end of the separation column to the single inlet at the first end of the buffer column.Type: ApplicationFiled: February 7, 2013Publication date: June 13, 2013Applicant: VBOX, INCORPORATEDInventor: VBOX, INCORPORATED
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Patent number: 8414684Abstract: A degas assembly including a low pressure fluid channel for carrying a wash fluid at a first pressure, a pressurized channel for carrying eluent including a gas at a second pressure higher than the first pressure, and a degas separator defining a fluid barrier between the low pressure fluid channel and pressurized fluid channel, the separator configured to retain liquid in the pressurized fluid channel and allow gas to flow through the separator to the low pressure fluid channel. The pressurized fluid channel may extend along an outer periphery of the low pressure fluid channel. The eluent may be received from an eluent generator at a pressure of at least about 3300 psi, and in various embodiments up to about 5000 psi. A liquid chromatography system and method are also disclosed.Type: GrantFiled: June 1, 2010Date of Patent: April 9, 2013Assignee: Dionex CorporationInventors: Yan Liu, Christopher A. Pohl, Michael McAdams, Hamish Small, Zhongqing Lu, Milton Liu, Khosro Moshfegh
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Patent number: 8389289Abstract: A gas chromatograph (GC) apparatus capable of detecting abnormality, in which a reference retention index is obtained from a result obtained by analyzing a given substance and a retention-index reference substance under adequate analysis conditions using a normal column, and stored in a storage section. Further, under a condition that the apparatus can perform normal analysis, the given substance is subjected to GC analysis to obtain a reference retention time, and the obtained reference retention time is stored in the storage section. A diagnosis processing section is operable to compare each of an actual retention time and an actual retention index with a respective one of the reference retention time and the reference retention index. If a deviation therebetween or abnormality is detected, the diagnosis processing section is operable to estimate a causal factor of the abnormality.Type: GrantFiled: September 10, 2009Date of Patent: March 5, 2013Assignee: Shimadzu CorporationInventor: Shuichi Kawana
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Publication number: 20130000485Abstract: A flow control system, method and device for performing thermal desorption is provided. In one embodiment, the system includes a first flow path in which gas flows from a first carrier gas inlet, through a first vessel in a first direction at a first flow rate to adsorb analytes on an adsorbent of said first vessel; a second flow path in which gas flows from a second carrier gas inlet, through said first vessel in the first direction at a second flow rate to further adsorb the analytes on the adsorbent of said first vessel; a third flow path in which a carrier gas flows through said first vessel in a second direction to carry desorbed analytes out of said first vessel; and wherein the second flow rate of carrier gas through said first vessel is greater than the first flow rate of carrier gas through said first vessel.Type: ApplicationFiled: June 29, 2011Publication date: January 3, 2013Inventors: Andrew Tipler, Greg Johnson, David J. Scott
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Patent number: 8322189Abstract: The present invention is an improvement to two-dimensional comprehensive gas chromatography. The improvement is a one valve switching modulator connecting the two separation columns. The valve includes either a two position eight-port valve or a two position twelve-port valve, and two transfer lines.Type: GrantFiled: August 14, 2009Date of Patent: December 4, 2012Assignee: ExxonMobil Research and Engineering CompanyInventor: Frank C. Wang
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Patent number: 8308854Abstract: A system for recycling helium carrier gas comprises: a bladder, the bladder interior fluidically configured so as to receive helium-bearing gas output from at least one of a split vent and a septum purge vent of a gas chromatograph; a compartment containing the bladder; a source of pressurized air or gas operable so as to supply pressurized air or gas into the compartment interior so as to compress the bladder containing the helium-bearing gas; a gas reservoir fluidically coupled to the bladder interior so as to receive the helium bearing gas from the compressed bladder interior; and at least one gas purification module configured so as to receive the helium-bearing gas from the gas reservoir and operable to remove contaminants from the helium-bearing gas, an output of the at least one gas purification module being fluidically coupled to a carrier gas inlet of the gas chromatograph.Type: GrantFiled: December 15, 2009Date of Patent: November 13, 2012Assignee: Thermo Finnigan LLCInventors: Edward B. McCauley, Matt A. Lasater
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Patent number: 8230719Abstract: The present invention is directed to a method for multidimensional gas chromatography for separating the analytes of a complex sample. The method comprises the steps of introducing the sample onto a first column whereby the sample is separated into at least two segments, introducing at least one segment into a heartcut device whereby the segments are selectively separated into at least two heartcut fractions, introducing at least one of the fractions onto a second column whereby at least one fraction is further separated into at least two analytes, introducing at least one analyte from the second column to a gas chromatography connector, introducing the analyte from the connector to a third column, and introducing the analyte from the third column into a detector whereby the analyte is analyzed and identified.Type: GrantFiled: April 27, 2010Date of Patent: July 31, 2012Assignee: MRIGlobalInventor: Chad Fisher
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Patent number: 8156788Abstract: A method for the superficial-phase chromatography of a product comprises the steps which are performed continuously in the following order, namely: an operation consisting in pumping a supercritical fluid; and operation consisting of injecting at least one sample of product into at least one chromatography column, a detection operation, and a fraction collection operation. The method comprises at least a first diversion along between an analytical channel and a preparatory channel, which diversion is performed prior to the supercritical fluid pumping operation and the analytical and preparatory channels each including respective supercritical fluid pumping operations. The method is also characterized in that the collection operation is common to both the analytical and preparatory channels. An installation used to implement one such method is described.Type: GrantFiled: February 22, 2006Date of Patent: April 17, 2012Assignee: PIC SolutionInventor: Mohamed Shaimi
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Patent number: 8134121Abstract: A chromatographic mass spectrometer 100, 150 is provided with a measuring portion 21 for measuring n-alkane of a number of different carbon numbers, and characterized by further having: a mass number storing portion 31 for storing the mass number for each n-alkane; and a mass chromatogram preparing portion 22 for preparing a mass chromatogram for each mass number by focusing on the mass number on the basis of the mass spectrum.Type: GrantFiled: October 31, 2006Date of Patent: March 13, 2012Assignee: Shimadzu CorporationInventor: Haruhiko Miyagawa
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Publication number: 20120048108Abstract: Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.Type: ApplicationFiled: November 7, 2011Publication date: March 1, 2012Applicant: SCHLUMBERGER TECHNOLOGY CORPORATIONInventors: William H. Steinecker, Jagdish Shah, Oleg Zhdaneev, Gordon R. Lambertus, Hua Chen
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Patent number: 8123834Abstract: Novel metal organic framework (MOF) molecules and methods of synthesizing them are described. MOFs are organometallic crystalline structures that have high sorption capacity due to high surface area, tailorable selectivity, an inert nature, and thermal stability at high temperatures. MOFs may be used as sorbents in preconcentrators for analytical devices to provide orders of magnitude of improved sensitivity in analyte detection. MOFs are also useful as sorbents in new compact and portable micropreconcentrator designs such as a modified purge and trap system and a multi-valve microelectromechanical system (MEMS) to achieve high gain in analyte detection. Further, MOFs may be used as coatings for novel microstructure arrays in micropreconcentrators where the microstructures are designed to increase the surface area to volume ratio inside the micropreconcentrator while minimizing the pressure drop across the micropreconcentrator.Type: GrantFiled: October 6, 2006Date of Patent: February 28, 2012Assignee: The Board of Trustees of the University of IllinoisInventors: Richard I. Masel, Zheng Ni, Mark A. Shannon
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Publication number: 20120017760Abstract: An apparatus and method for rapid fractionation of hydrocarbon phases in a sample fluid stream are disclosed. Examples of the disclosed apparatus and method include an assembly of elements in fluid communication with one another including one or more valves and at least one sorbent chamber for removing certain classifications of hydrocarbons and detecting the remaining fractions using a detector. The respective ratios of hydrocarbons are determined by comparison with a non separated fluid stream.Type: ApplicationFiled: July 21, 2010Publication date: January 26, 2012Applicant: UT-BATTELLE, LLCInventors: Charles S. Sluder, John M. Storey, Samuel A. Lewis, SR.
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Patent number: 8099995Abstract: An apparatus and a method of making a measurement using the same. The apparatus includes a channel through which a fluid flows, a detector, and a choked flow channel. The detector measures a property of the fluid by generating a signal that depends on that property. The signal generated also depends on a pressure of the fluid in the detector. The choked flow channel receives the fluid at a first pressure after the fluid has been measured by the detector, and then transmits the fluid to a downstream location at a second pressure. The fluid reaches a supersonic velocity at one point in the choked flow channel. The choked flow channel may include a convergent-divergent nozzle or an orifice in a structure located in the choked flow channel.Type: GrantFiled: December 16, 2008Date of Patent: January 24, 2012Assignee: Agilent Technologies, Inc.Inventor: Phillip W. Barth
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Patent number: 8088627Abstract: A method and apparatus for the in-situ, chemical analysis of an aerosol. The method may include the steps of: collecting an aerosol; thermally desorbing the aerosol into a carrier gas to provide desorbed aerosol material; transporting the desorbed aerosol material onto the head of a gas chromatography column; analyzing the aerosol material using a gas chromatograph, and quantizing the aerosol material as it evolves from the gas chromatography column. The apparatus includes a collection and thermal desorption cell, a gas chromatograph including a gas chromatography column, heated transport lines coupling the cell and the column; and a quantization detector for aerosol material evolving from the gas chromatography column.Type: GrantFiled: December 10, 2004Date of Patent: January 3, 2012Assignees: Aerosol Dynamics, Inc., The Regents of the University of CaliforniaInventors: Susanne V. Hering, Allen H. Goldstein
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Patent number: 8062516Abstract: A connector for fastening a gas chromatography capillary column to chromatography equipment includes a securing nut and ferrule on a first portion of the connector for releasably holding the capillary column in a position relative to a second portion of the connector. The first portion rotates relative to the first portion and translates a limited amount relative to the first portion. A pin on the first portion extending into an annular groove around a circumference of the first portion may allow this rotation and limited translation. The second portion has a threaded end adapted to screw into the chromatography equipment with the first portion remaining relatively rotation free as the second portion is screwed into place.Type: GrantFiled: July 9, 2008Date of Patent: November 22, 2011Assignee: Phenomenex, Inc.Inventors: Doug Silva, Jim Archer, Sky Countryman, Kory Kelly
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Publication number: 20110236295Abstract: Polymeric ionic liquids, methods of making and methods of using the same are disclosed.Type: ApplicationFiled: August 10, 2009Publication date: September 29, 2011Applicant: UNIVERSITY OF TOLEDOInventors: Jared L. Anderson, Fei Zhao, Yunjing Meng, Qichao Zhao
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Patent number: 8011224Abstract: A feeding device for enriching and feeding a fluid sample into a chemical detector, the feeding device comprises (a) a sorbent element having a sorbent material for sorbing at least one target chemical present in the fluid sample; (b) a desorbing mechanism for generating conditions for the sorbent material to desorb the at least one target chemical out of the sorbent material, thereby to provide an enriched fluid sample; and (c) a loose connector, for providing a loose connection between the feeding device and the chemical detector, such that when the sorbent material desorbs the at least one target chemical, the chemical detector is fed by the enriched fluid sample, and when the sorbent material sorbs the at least one target chemical, the chemical detector is fed by environmental fluids.Type: GrantFiled: June 1, 2005Date of Patent: September 6, 2011Assignee: Israel Institute for Biological ResearchInventors: Shai Kendler, Adi Zifman, Netzah Gratziany, Amnon Sharon, Gad Frishman
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Publication number: 20110139001Abstract: This invention relates to a process for the enrichment of isotopes by chromatography on a saturated stationary phase. The process provides a more efficient method than the existing methods.Type: ApplicationFiled: October 28, 2008Publication date: June 16, 2011Applicant: ISOSILICON ASInventors: Pierre Hilaireau, Wieslaw Majewski
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Patent number: 7954360Abstract: The present invention is directed to a field-mounted analyzer having a graphical user interface (GUI). The analyzer has a display screen visible from the exterior of the housing. A plurality of magnetically-actuatable switches are mounted behind the display screen. The GUI has a plurality of windows that may be displayed on the display screen. Navigation through the windows is accomplished by activating switches aligned with graphical navigation icons in the windows.Type: GrantFiled: October 26, 2007Date of Patent: June 7, 2011Assignee: ABB Inc.Inventors: Jonathan W. Asher, Anthony P. Walker, James Michael Robinson
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Publication number: 20110123878Abstract: A pressure swing adsorption process wherein a gas mixture comprised of a reformate gas and a biomass gas is processed to remove contaminants.Type: ApplicationFiled: November 23, 2010Publication date: May 26, 2011Inventor: Juzer Jangbarwala