Abstract: An ampoule which is hard to crack on a barrel while increasing cleavability required for a hermetical container end. An ampoule (20) is provided with a front edge portion (1), a main body (2), a connection (3), and a joint (4), wherein a hermetical container end (10) which includes the front edge portion (1), the joint (4) and the connection (3) is formed separately from the main body (2), and the joint (4) breaks when a force is applied from a lateral direction with respect to the central axis (5), so that a head portion of the connection (3) which is circular truncated cone shaped is exposed and the space portion (13) of the connection (3) becomes an open end.

Abstract: The take-off needle comprises a main hollow lance having a distal end adapted to perform a pricking operation, said hollow lance being connected to two pipes each provided with a spigot for it to be connected to a tube, said needle further comprising a body for holding the main hollow lance, said holding body defining two internal cylindrical surfaces forming said pipes, the main hollow lance comprising, at its proximal end, a sleeve having an internal channel of which the distal end is connected to the proximal end of the main hollow lance, and of which the proximal end opens into the holding body, said sleeve comprising at its proximal end two crescent-shaped surfaces inclined towards the interior of the internal channel and towards the distal end of the sleeve, each of said crescent-shaped surfaces being disposed so as to extend in line with one of the internal cylindrical surfaces of the holding body.

Abstract: A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitted in to a circular contour in the housing. The outer diameter of the protrusion on the distal end of the cartridge is chosen as a larger diameter for a higher concentration of insulin. In this way only a cartridge containing the correct concentration or a lower concentration fits into a delivery system designed for a specific concentration of insulin.

Abstract: A container shaped in the form of a teardrop is used interchangeably in upright and inverted orientations. The container is used in an upright orientation to allow a person to directly drink liquids. In the inverted orientation, the container is mounted at a height over the user and allows versatile and controlled administration of liquids even to bedridden patients. The controlled administration provides the advantages of precise and measured dispensation of liquids, on-site or remote monitoring of dispensation, and control of dispensation by a patient or a care-giver. This type of liquid dispensation is not as invasive as other medical treatments (e.g., intravenous treatment), and therefore can be employed both at home and at hospitals with comparable effectiveness.

Abstract: A person having diabetes will often be required to take both slow acting and fast acting forms of insulin. It is important to be able to distinguish readily between medicament cartridges containing different medicaments. The present invention enables more ready distinction as between medicament cartridges containing different medicaments.

Abstract: Many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that the different forms of medicament do not become confused. To this end, a medicament cartridge is provided comprising a sleeve having a bottleneck providing a flange at a first end, a fluid impermeable membrane secured across the first end by a metal cap beaded beneath the flange, and a displaceable piston located internally of the sleeve towards a second end of the sleeve, a collar located against an external periphery of the cartridge housing beneath the flange and an adaptor top press fit over the cap and the collar, the adaptor top being provided with means to act upon the collar thereby to retain the adaptor top on the sleeve.

Abstract: According to the inventive method, a first element (22) of the assembly which is formed by the base (8) and the cap (22) of the device, is produced from a harder material than the second element (8) of said assembly (8, 22), the first element (22) is provided with at least one peripheral edge (30) for tightly penetrating an area facing the second element and the/each edge (30) of the first element (8) is/are covered with a lubricating agent which is suitable for forming a lubricating film (26) once the covering process is complete. Said film remains in place on the sealed edge(s), during the relative displacement of the cap (22) and the base (8), as well as when the cap (22) and base (8) are immobile in relation to each other. This film ensures that the cap can be fairly easily disassembled from the base.

Abstract: A container for receiving liquids with different concentrations of an active substance that is to be administered or dosed, wherein the container includes a hollow body and a displaceable element for expelling the liquid is located for longitudinal movement in the hollow body, and wherein the cross-sectional surface area of the hollow body is inversely proportional to the concentration of the substance, such that, with identical strokes or longitudinal movements of the displaceable element, the discharged amount of active substance remains independent of the concentration of the substance in the container.

Abstract: A recipient has a body designed to contain a fluid and an orifice by which the fluid may be introduced into the body. The recipient is equipped with a system for the sterile transfer of the fluid from inside the body. The transfer system comprises a deformable and impervious wall, wherein the wall is positioned with respect to the recipient so that it forms a closed and sterile space inside which the orifice is located, a fluid communication device between the closed space and the outside of the recipient, wherein the device may be handled without compromising the sterility, and a seal structure associated with the orifice, wherein the seal structure is at least partially located inside the closed space so that it may be moved between an open position and a closed position of the orifice.

Abstract: The invention relates to a bag system for the cryopreservation of body fluids, that is blood, bone marrow or umbilical cord blood, the parts of the bag system being sterilized, and separable from one another, wherein liquids which permit and/or assist cryopreservation are located in the bag system and/or may be introduced into the bag system in a sterile form. The bag system, at least, comprising: a device for the direct removal of body fluid (1) from the living body, a region or number of regions for mixing the liquids with the body fluid and/or for storing the mixture of liquids and body fluid, a number of shut-off elements (2) and connecting lines (3) and an inlet element (4) and/or an outlet element (5).

Abstract: A flexible container incorporating flexible front and rear sheets and one or more container ports disposed in between the sheets are discussed. The one or more container ports each has a pliable attachment flange and an integrally molded nozzle. The pliable attachment flange has a first configuration whereby the attachment flange collapses to enable heat sealing the attachment flange to the sheets and thereafter substantially recovers its shape to provide a fluid pathway with the port. Various terminal ports, terminal caps, and rubber septums may be useable with the one or more container ports.

Abstract: Vacuum break vial assembly and method for reducing the incidence of nosocomial infections, comprising a vial stopper having a 2-part withdrawn-fluid volume compensation assembly having a barbed vent element that secures an apertured needle sheath, a bladder-retainer tube and an expandable/unfoldable bladder. The vial has an aluminum cap holding a plastic flip-off top that removes a central portion of the cap to permit access by hypodermic needle through the stopper into the needle sheath. No pre-pressurization of the vial by ambient contaminated air via the hypodermic can occur. Rather, the needle is inserted in the vial through the stopper and the medicinal fluid withdrawn. Air is inlet into the separate bladder which expands to permit withdrawal of fluid into the hypodermic without vacuum lock. No air having pathogen vectors is introduced into the vial medicinal fluid as the bladder isolates volume-compensating air from the medicinal fluid. Plural embodiments are shown.

Abstract: A vial adapter suitable for use in transferring fluid from a vial to a needleless syringe, the vial having a top end sealed with a septum.

Abstract: A connector for use in connecting a container of liquid nutrients to an enteral feeding tube to supply the liquid nutrients to a patient includes an integrally formed spike projecting into a cavity defined by an interior surface of a body of the connector. An air passage in communication with the cavity extends through the spike to outside the connector. A filter is secured to the end of the passage outside the connector. The body of the connector is free of structure that both defines any portion of the liquid passage and is formed for penetrating the puncturable seal of the container.

Abstract: The present invention relates to a topical or cosmetic system that includes a first element capable of acting as an electron donor and a second element capable of acting as an electron acceptor. Such first and second elements are spaced apart by a predetermined distance across a skin surface. The system also includes a third element extending over the predetermined distance across the skin surface, while the third element contains an electrically conductive medium for electrically connecting the first and second elements, thereby generating an electrical current that flows across the skin surface from the first element through the conductive medium to the second element in the absence of any power source. The present invention also relates to methods of using the above-described system for preventing or treating skin damage.

Abstract: A bottle-type blow-molded plastic infusion container that can be set in an upright position. When liquid is discharged from the container, almost no dead space occurs in shoulder and bottom portions (required amount of air to be placed in the container to remove residual liquid is less). The blow-molded container has a mouth section (1), a neck section (2), the shoulder section (3), a barrel section (4), and the bottom section (5). The barrel section (4) has a pair of broad side faces (41, 41) and a pair of narrow side faces (42, 42). The bottom section (5) is formed in a shape symmetrical about a longitudinal axis of the bottom section (5) and bent inward in a V shape. Further, the shoulder section (3) has a pair of broad side faces (31, 31) and a pair of narrow side faces (32, 32). In the narrow side faces (32, 32) are formed grooves (33, 33) symmetrical about a longitudinal axis and bent inward in a V shape.

Abstract: The invention relates to a kit for parenteral administration of drugs, particularly a kit for the infusion of those medicaments dissolved in solvents that extract toxic components from PVC, which is also suitable for the infusion of highly active medicaments, said kit ensuring a safe administration both for the patient and for healthcare staff.

Abstract: The invention provides container systems, kits and methods for peritoneal dialysis (PD) solutions. Such a system, for example, includes a first compartment that contains a PD osmotic agent and a second compartment that contains a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. The invention provides, in other aspects, such systems, kits and methods that provide protective structure which inhibits breaking of a seal prior between the second compartment and an outlet of the system, prior to breaking of a seal between the first and second compartments.

Abstract: A closure device (10) for a container (12) includes a filling device (14) that can be attached to an opening (16) of the container (12) A closure structure such as a membrane (18), a system (34), or a duckbill closure (54, 84) is attached to the filling device (14) in such a way that the opening (16) of the container (12) is sealed when the filling device (14) is attached to the opening (16). The closure structure is coated at least partially with polytetrafluoroethylene (22, 38, 60, 94) on one side (20, 40, 58, 90) that is accessible from outside the container (12) in the assembled state of the filling device (14) on the container (12).

Abstract: At least one tab may extend through at least one opening in a retaining member configured to cover at least a portion of a head of a reservoir body and a portion of a septum supported by the head of the reservoir body. A retaining member may be configured to cover at least a portion of a first head of a reservoir body and a portion of a septum supported by the first head of the reservoir body, and the reservoir body may have a second head having at least one tab. A retaining member located in a head of a reservoir body may be for retaining a septum on the head of the reservoir body, and the head of the reservoir body may have at least one tab.

Abstract: A liquid storage bag having a partition wall allowed to be peeled easily and not peeled by an accidental drop, etc. The liquid storage bag is one wherein the upper part thereof is closed with a freely and closable zipper, the bottom thereof is provided with a liquid outlet, and an easily peelable partition wall (a weak seal part) is provided close to the zipper. The internal space of the liquid storage bag is divided liquid-tightly into upper and lower parts through this weak seal part, liquid is stored in the lower part of the internal space (liquid storage chamber), and the weak seal part is formed in outside-convex form at a center and increased in width at both end parts thereof.

Abstract: A surgical cassette having an aspiration chamber or infusion chamber with a sensing portion and a storage portion. The sensing portion has a small transverse cross sectional area and facilitates accurate fluid level measurements. The storage portion has a larger transverse cross sectional area to facilitate fluid storage.

Abstract: Disclosed is a foil pocket (10) comprising at least one carrier foil (11) and at least one lidding foil (12). A foil-type or sheet-type product (1) is enclosed in a gas-tight and moisture-proof manner between the carrier foil (11) and the lidding foil (12), i.e. the joined parts, and is surrounded by a joining zone (30). At least one joining zone section (33, 34, 43, 44) which is not disposed perpendicular to the tear-off peeling direction (9) and is located laterally next to the product (1) widens and/or narrows in the joining zone (30) transversal to the tear-off peeling direction (9). At least the first quarter of the joining zone section (13, 43) that is not disposed perpendicular to the tear-off peeling direction (9) is provided with no widened area (35-41) and/or no narrow area (55-58). The invention make it possible to create a primary packaging which dispenses with the use of auxiliary means such as gloves, tweezers, or similar for applying systems containing active substances.

Abstract: Systems and methods handle air and rinsing fluid during fluid processing. The systems and methods eliminate air from a fluid processing system prior to, during, and after use. The systems and methods provide a connector assembly for establishing fluid flow from a fluid source. The connector assembly has discrete first and second passages that prevent communication between the fluid in first passage and the fluid in the second passage. Prior to system use, the connector assembly may be utilized in a priming function to remove residual air from a fluid circuit prior to use. The connector assembly may also be utilized after use to perform a rinse-back function.

Abstract: A fluid collection apparatus is provided that includes a housing configured for receipt of fluid and/or tissue for collecting fluid therefrom. A holder is configured with the housing to receive an evacuated tube. The holder can include a needle hub supporting a needle cannula in fluid communication with a port extending into a fluid well of the housing. A sloped bottom surface of the housing directs fluid to the fluid well. A sidewall extension or support component extends downward beyond the sloped bottom surface to allow the housing to be stood upright on a flat surface. In certain embodiments, the apparatus includes a tubular cavity to provide a recessed location of the needle cannula for preventing accidental needle injuries. An optional cap provides further shielding from needle cannula and safely maintains fluid in housing after use.

Abstract: A device for the treatment of a medical fluid including a permanently installed fluid treatment machine and a cassette with fluid-carrying channels as well as an elastic matt placed between these two items. The matt channels are recessed in the elastic matt and are provided with slits. Via the matt channels, an optimised vacuum distribution takes place and the slits serve the purpose of removing air between the cassette and the fluid treatment machine.

Abstract: Problems To provide a portable drug solution container that is filled with nearly one dose of throat drug solution, ensuring easy unsealing and use and realizing unsealing with the direction of nozzle fixed. Means for Solving Problems There is provided disposable portable drug solution container (1) filled with a small amount of drug solution, including platelike member (5) capable of being folded at given position into at least two segments and, bonded fast to the backside of the platelike member (5), bag member (2) filled with a drug solution, and further including nozzle (6) extending from given position of the container (1), wherein in the state of having the platelike member (5) folded, there is realized communication of the nozzle (6) with the interior of the bag member (2).

Abstract: A blood container and a method is provided for a blood transfusion, in particular, for a blood transfusion by which blood a patient is losing is collected, fat is separated from the blood, and the non-fat blood is transfused into the patient so as to prevent side-effects including fat embolism and the like from occurring due to the fat after the blood is transfused into the patient. The blood container includes a soft case and hard case. A first tube is formed at one side of the hard case to inject blood into the soft and hard cases and a second tube is formed adjacent to the first tube to discharge the blood out of the soft and hard cases, wherein the soft and hard cases have open side that adhere to each other to form a single body.

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

Abstract: A port closure system for use with a fluid container having fluid ports includes administrative and additive port closure assemblies. The administrative assembly receives a piercing pin and includes an administrative housing which seals closed one fluid port. A sleeve extends from an interior surface past a base surface in the administrative housing. The sleeve has an upper portion and a lower portion, of differing diameters. A cap assembly mates with the administrative housing, sealing the interior surface of the administrative housing. A removable cap provides access to the interior surface. The additive assembly receives a needle and includes a reseal housing which seals closed another fluid port. Another cap assembly mates with the reseal housing, sealing an interior face of the reseal housing. Another removable cap provides access to the interior face. A reseal element is mechanically retained between the reseal housing and cap assembly.

Abstract: A blood chamber for extracorporeal blood circuits comprises a container body (2) made in a single piece by blowing of a plastic material, and has a plurality of connection ports (3, 4) for fluid communication with outside; each connection port (3, 4) comprises a tubular mouth (6) having a truncoconical internal surface (61) which is coupled in a fluid-proof coupling to a tubular first part (101) of an insert (10), made by injection molding of a plastic material. The insert (10) has a truncoconical and smooth internal surface (102) which is coupled by gluing with a solvent to an end zone of a fluid transport tube (7, 8). The coupling between the blood chamber and the fluid transport tubes is very strong and reliable. The blood chamber is part of an extracorporeal blood circuit which is operatively associated to a dialysis machine.

Abstract: A dispensing device comprises a sealed package including a collapsible compartment and an administration assembly. The administration assembly includes a delivery device in fluid communication with a substance within the sealed package. A compression panel collapses the compartment to dispense a substance through the delivery device. Embodiments for a single use dispenser for hypodermic administration of a unit dose of a therapeutic fluid, as well as therapeutic packages and methods for administering therapeutic substances to subjects, are also provided.

Abstract: A needle assembly has a first body and a guide rod supported for sliding movement between an extended position and a retracted position. A second body is attached to the guide rod. The second body is relatively farther from the first body when the guide rod is in the extended position and relatively closer to the first body when the guide rod is in the retracted position. The guide rod is biased to the extended position. The second body supports a venting needle that extends beyond the second body by a fixed length. A liquid handling needle is coupled to the first body. Sliding movement of the guide rod toward the retracted position retracts the second body and the venting needle relative to the liquid handling needle.

Abstract: The invention relates to an injection device for the needle-free injection of a medium. Said injection device comprises an injector device and an ampoule unit, said ampoule unit comprising a base (4) holding the medium to be injected. Said base comprises a jacket (5) which exerts pressure on the base, said jacket completely enveloping the base in the longitudinal axial direction.

Abstract: Described here are unit dose containers, methods, and kits for treating asthma and other pulmonary conditions by nebulization. The unit doses of active agents are provided in a low volume formulation, which results in faster nebulization of the unit doses. The containers are also formed to minimize internal surface area so that effective re-dispersion of the active agents can be achieved while reducing adsorption to the walls of the containers.

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

Abstract: A communicating member for a medical container contains a plate member 4 having a first opening 5 and a second opening 6, a first connection port 15 including the first opening 5, a plug 9 that obturates the first opening 5 and a first approximately cylindrical member 19 that is in communication with the first opening 5, a second connection port 16 including the second opening 6 and a barrier member 13 that obturates the second opening 6, and a continuous wall 17 disposed on the plate member 4 on the first approximately cylindrical member 19 side and disposed upright on the plate member 4 such that the continuous wall 17 encloses the first opening 5 and the second opening 6 when the plate member is viewed from above; and the first approximately cylindrical member 19 is provided with a first communication part 20 that has an opening on the second opening 6 side.

Abstract: Disposable ampoule for use in an aerosol generating device, comprising: a medicament container that contains a medicament and is formed of a container body (10) and a container bottom (11), and a predetermined break point (12) that at least partly surrounds the container bottom, characterised by a collar (15) that surrounds the predetermined break point (12) at its outside and extends the container body (10) over and beyond the container bottom (11).

Abstract: Methods of treating neuronal disorders, such as mechanical neuronal traumas and neurodegenerative disorders, with TWEAK or TWEAK-R blocking agents are presented.

Abstract: A port closure system for use with a fluid container having fluid ports includes administrative and additive port closure assemblies. The administrative assembly receives a piercing pin and includes an administrative housing which seals closed one fluid port. A sleeve extends from an interior surface past a base surface in the administrative housing. The sleeve has an upper portion and a lower portion, of differing diameters. A cap assembly mates with the administrative housing, sealing the interior surface of the administrative housing. A removable cap provides access to the interior surface. The additive assembly receives a needle and includes a reseal housing which seals closed another fluid port. Another cap assembly mates with the reseal housing, sealing an interior face of the reseal housing. Another removable cap provides access to the interior face. A reseal element is mechanically retained between the reseal housing and cap assembly.

Abstract: A device for drawing fluid from a lumen, and particularly blood from a blood vessel, is disclosed. The device may provide indication of the entry of an intravenous cannula into the lumen. The device may include a central body having an outer wall and an inner fluid passage. The device may include a luer-type adapter to permit the attachment of an I.V. infusion set of various lengths (“butterfly needle”) and or any luer-type fitting attached to an existing device. The outer wall of the central body may be transparent or translucent to permit the detection of fluid within the inner fluid passage. A front cannula may extend from one end of the central body and a rear cannula may extend from the other end of the central body. Both the front and rear cannulae may communicate with the inner fluid passage. An air-permeable flexible sleeve may surround at least a tip portion of the rear cannula. The air-permeable flexible sleeve may act as a venting member positioned between the rear cannula and the ambient.

Abstract: A flexible non-PVC, non-DEHP container or bag for medical fluids has a container body formed of a multiple layer polyolefin film. The container has one or more ports equipped with a polyolefin fill tube and port closure assembly. The container has a low moisture vapor transmission rate.

Abstract: A disposable container for biologic materials comprising a sheet of flexible material with an access area integrally molded in the sheet. At least one port in the access area passes fluid into the container. The sheet is folded along the access area such that an upper part is adjacent a lower part, and the upper part is attached to the lower part. The method for making the container includes forming a sheet having an access area integrally molded in the sheet, folding the sheet along the access area, and joining the upper part to the lower part. The upper and lower sheets and the access area are injection-molded as a single, unitary piece. This process uses a mold having a central triangular prism and conforming upper and lower blocks.

Abstract: As an Orthopedist I have found that if I have to hold both the vial and the syringe while I draw up medications it poses numerous problems. The first problem is that when I was aiming the needle towards the small vial in my hand, if my aim were to be off there was a likelihood that I would end up sticking my hand. Another problem was that having only one free hand to draw up the syringe (while the other hand was holding the vial) required me to contort my fingers in such a way that led to fatigue. Another problem that came up was that in certain situations administering injections had to be done under aseptic conditions which became more difficult when I had to handle the vial at the same time. The Hands-free medicine vial holder solves all these problems.

Abstract: Apparatus (1) for the introduction of air into enteral containers (2). A valve (14) is provided in a connection member (4) connecting the enteral set with the container (2) containing the enteral liquid and controls the introduction of air corresponding to the consumption of the enteral liquid. The valve (14) may include an oleophobic filter material that covers the air inlet (16) projecting into the connection member (4). The valve (14) on the side facing the container (2) is provided with a cutting device (20) for the foil closure of aluminum or plastics closing the container (2) in its initial delivered state. The cutting device (20) may be a circular or partly circular projection (28) rising from a low side (30) to a high side (32).

Abstract: A system and method for harvesting, storing, and implanting biological units, in particular hair follicular units (FUs). The system is particularly useful to facilitate hair transplant procedures. FUs are harvested from a body surface, either attached to a patient or in a strip of removed tissue, and shuttled into a cartridge having a plurality of receptacles. The receptacles are open in a distal direction toward a removal tool, but a cover over the proximal ends of the receptacles prevents the FUs from continuing out of the cartridge. The cover is made of a permissible medium, which may be fluid permeable and/or puncturable. One way to shuttle the FUs is to provide a pressure differential, such as by applying suction to the proximal end of a receptacle. The shuttle subsystem may be incorporated within an overall automated or robotic system, or the shuttle subsystem may form part of a semi-automated or even manual apparatus.

Abstract: A head part (11) for a multi-chamber tube bag (1) with a multi-component mass which can be pressed out, having a main chamber (2) for a first component and two secondary chambers (3, 4) for two other components, has a disk-shaped contact surface (12) for the multi-chamber tube bag (1) surrounding a press-out opening (13). At the contact surface (12), a plurality of raised portions (14) project toward the multi-chamber tube bag (1) and are provided at the head part (11) for narrowing the outlet regions (5, 6) of the two secondary chambers (3, 4) of the multi-chamber tube bag (1) when the multi-chamber tube bag (1) bears against the contact surface (12).

Abstract: Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.

Abstract: Method and apparatus are described for ensuring that blood transfused into a patient is the correct blood for that patient, and that a complete audit trail is created that will allow later tracing of blood from donation through to transfusion.

Abstract: A port closure system for use with a fluid container having fluid ports includes administrative and additive port closure assemblies. The administrative assembly receives a piercing pin and includes an administrative housing which seals closed one fluid port. A sleeve extends from an interior surface past a base surface in the administrative housing. The sleeve has an upper portion and a lower portion, of differing diameters. A cap assembly mates with the administrative housing, sealing the interior surface of the administrative housing. A removable cap provides access to the interior surface. The additive assembly receives a needle and includes a reseal housing which seals closed another fluid port. Another cap assembly mates with the reseal housing, sealing an interior face of the reseal housing. Another removable cap provides access to the interior face. A reseal element is mechanically retained between the reseal housing and cap assembly.