Abstract: The present invention relates to a disposable bag which comprises a multilayer film for accommodating a fluid, and a device which comprises a support holder for the disposable bag according to the invention in which the disposable bag is arranged. The present invention also relates to a process for the production of the disposable bag.

Abstract: This patent application teaches methods and apparatus of an efficient disposal chain system which includes a process of receiving fluid enclosing containers, transforming said containers into collection containers by integrating said containers into vacuum canister collection systems. Such a collection system includes a remote vacuum source configured to draw a vacuum force away from said container and towards said container. Such a vacuum source is configured to draw room air. Such a force is configured to draw waste materials along a path towards said collection container. A transformation of said containers includes deriving said containers from supply chains and transforming said containers into said collection systems at least in part by supporting said containers inside said canisters from below utilizing various configurations of measurement stands, said stands configured to support and accommodate various sizes, types and shapes of said containers.

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

Abstract: The present invention consists of a venous blood reservoir that has a separate blood chamber to filter vent blood and a separate chamber to filter sucker blood. The two blood chambers are separated by a common wall and are in fluid communication along their top assuring that vacuum applied to the top of either is equally applied to the other. A mean to form communication across the wall allows the user to either accumulate sucker blood in its chamber while letting vent blood to flow freely to the venous blood chamber. Alternately, user can let the blood in the sucker chamber to combine with the venous blood freely too.

Abstract: A container for re-suspending sedimented medicament comprises a reservoir for containing a suspension of particles in a liquid, a dispensing portion, and a sealing portion. The sealing portion is arranged to be in fluid communication with the reservoir via an orifice. The orifice is positioned between the dispensing portion and the sealing portion, and allows a turbulent flow of the liquid from the reservoir into the sealing portion to enable re-suspension of particles that have sedimented out of the liquid in the sealing portion.

Abstract: A port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a port housing for connection to a second container, and a retainer for connection to a first container, wherein the retainer rotates relative to the port housing and is constructed to move axially within the port housing. An actuator is axially fixed within the port housing and forces a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing. The assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing.

Abstract: A connector according to the invention includes a first connection region for connecting a first container, a piercing element and a break-open element, wherein the piercing element has a first end section and a second end section and a channel, running from the first end section to the second end section, for transporting a medicinal active substance, wherein the first end section is formed for piercing a membrane of the first container connected in the first connection region, and, at the second end section, the break-open element is attached such that it can be broken open and/or broken off, wherein, in the attached state, the break-open element seals the channel of the piercing element in liquid tight fashion.

Abstract: A bottle-type blow-molded plastic infusion container that can be set in an upright position. When liquid is discharged from the container, almost no dead space occurs in shoulder and bottom portions (required amount of air to be placed in the container to remove residual liquid is less). The blow-molded container has a mouth section (1), a neck section (2), the shoulder section (3), a barrel section (4), and the bottom section (5). The barrel section (4) has a pair of broad side faces (41, 41) and a pair of narrow side faces (42, 42). The bottom section (5) is formed in a shape symmetrical about a longitudinal axis of the bottom section (5) and bent inward in a V shape. Further, the shoulder section (3) has a pair of broad side faces (31, 31) and a pair of narrow side faces (32, 32). In the narrow side faces (32, 32) are formed grooves (33, 33) symmetrical about a longitudinal axis and bent inward in a V shape.

Abstract: A one-piece bottle is provided, the bottle having a capacity that does not exceed 10 ml, containing enteral feeding material, and having a top end with a threaded section and a bottom end comprising a funneled connector port; and a threaded cap dimensioned to mate with the threaded section of the one-piece bottle; wherein the funneled connector port connects to an enteral feeding assembly; wherein the threaded cap provides a leak proof seal such that there is no exposure point until it is used for feeding, thereby preventing contamination.

Abstract: A noise dampening film is provided, and in particular, a film having at least one quiet layer that comprises a polymer resin and from about 5 to 50 weight percent of a styrene-vinyl polyisoprene-styrene block-co-polyisopyrene block triblock polymer. The quiet layer has a tan delta of at least about 0.27 or greater at a temperature range between about 17° C. and 40° C.

Abstract: Device (5) for filtering blood including a filter unit (7) having a blood filter, an inlet (8) for blood to be filtered and being connectable to an artery of a patient and a blood outlet (9) for filtered blood and being connectable to a vein of the patient, and having a filtrate container (6,14), that encloses the filter unit (7), for receiving filtrate (12) passing through the blood filter during a filtering process and that the filtrate container (6,14) is a closed container, which in a filled state is arranged to establish a counter-pressure over the blood filter, whereby the filtering process is interrupted. The invention also concerns a system including the above device.

Abstract: A method for collecting and filtering biological material from blood and other fluids during a surgical procedure includes: attaching a first cover including a suction port and an intake port to a collection trap; attaching a suction source to the suction port; attaching an instrument to the intake port, through which blood and tissue are suctioned and received into the collection trap; filing the collection trap with blood and tissue; removing the collection trap from the first cover; attaching a second cover to the collection trap in place of the first cover, the second cover including a suction port and a plunger, the plunger including a press head having a screen portion permitting blood and other fluids to pass; attaching a suction source to the suction port of the second cover; separating the blood from the tissue by deploying the plunger; and drawing off the blood through the suction port.

Abstract: An injector system including a docking station and a cassette and various transfer devices for transferring fluid from a bulk fluid container to a reservoir in the cassette are described herein along with methods for using such devices and systems to inject fluid from the bulk fluid container into a patient.

Abstract: A pump cassette is configured for coupling with a pump device. The pump cassette may include a fluid lumen adapted for passage and propulsion of an infusion fluid toward a patient; a valve assembly that can be actuated to regulate fluid flow through the fluid lumen; and a frame coupled to the fluid lumen and the valve assembly. The frame is adapted to be inserted into a seat of a pump device. The frame is configured to be inserted into the seat only when aligned in a predetermined orientation relative to the seat.

Abstract: A system for mixing contents of a first container with contents of a second container. The system includes a first container, a second container, a device for establishing fluid communication between the first container and the second container, and a hanger for hanging the system, wherein the hanger is operable only when fluid communication between the first container and the second container has been established. The system can be used in a method for preventing medication delivery errors.

Abstract: The invention relates to a blood plasma collecting flask made of plastic for the storage of blood plasma in the frozen state, comprising a flask body (1) which in the horizontal section has a cross-section with a rectangular basic shape and has on its upper side a flask neck (2), wherein the lateral faces of the flask body (2) respectively define a flat or slightly inwardly curved area (3) adjoining which are areas rounded towards the face surfaces.

Abstract: The present invention provides an apparatus comprising a housing and a flexible reservoir adapted to contain a fluid and having a septum member formed from a needle-penetratable self-sealing material. The flexible reservoir is arranged within the housing in combination with mounting means arranged within or formed by the housing, wherein the mounting means engages the septum member to thereby mount the flexible reservoir relative to the housing. In this way a secure fixation between the reservoir and the housing is provided without having to interfere with the general flexibility of the reservoir, e.g. substantially the entire flexible reservoir apart from the outlet/mounting means may be arranged free to move relative to the housing, this allowing the reservoir to be emptied to a high degree.

Abstract: The invention comprises a novel apparatus for delivering a nutritive substance comprising a container body having a base at one end thereof, an upper portion adapted for removable receipt of a closure, the upper portion defining an opening therein, and a chamber defined by the container body, the chamber being in fluid communication with the upper portion opening. A seal is bonded across the upper portion opening of the container and is adapted to provide an airtight seal across the opening. A closure is removably coupled to the container upper portion. A nutritive substance is coated onto an element selected from the group consisting of an inner surface of the container upper portion, the closure, an insert positioned above the seal, and combinations thereof. The seal prevents contact between the nutritive substance and the contents of the container until the seal is removed or pierced.

Abstract: A mixing system (1) adapted to allow first contents of a first container (2) and second contents of a second container (3) to mix to form a material. The mixed material is retrieved to a syringe (20) without being foamed. The mixing system (1) comprises a transfer unit (5) which is adapted to receive the first container (2) at a first port (11), the second container (3) at a second port (12) and the syringe (20) at a third port (13). The transfer unit (5) further houses a number of fluid pathways (14, 15, 16) interconnecting the three ports (11, 12, 13) as well as a number of flow control members (17, 18, 19, 22) for controlling fluid flow between the containers (2, 3) and the syringe (20).

Abstract: A bodily fluid drainage assembly can include a fluid bag and one or more covers. The assembly can include one or more volume indicators from which an approximate volume of a bodily fluid that is retained within the bag can be ascertained. In some arrangements, a cover includes a volume indicator that defines an opening through which a transparent or semitransparent portion of the bag can be viewed.

Abstract: A first connector is provided and includes a first connector body having a cylindrical outer tube, a cylindrical inner tube, and a hub; a hollow needle supported by the hub; a first sealing member supported by the inner tube; a coil spring that biases the hub in a proximal direction and biases the first sealing member in the distal direction; and gripping and pressing members disposed on the outer tube. A plurality of pawls are formed on a flange of the hub. A plurality of ratchet teeth are formed on an inner circumferential portion of a proximal portion of the outer tube. Each of the ratchet teeth and each of the pawls of the hub form an engagement-disengagement mechanism.

Abstract: The method described herein reduces the amount of aggregating metal released into solutions of Interferon-?.

Abstract: A novel and non-obvious apparatus, system, and method for managing respiratory secretions and fluids in sections of artificial airways. In an embodiment of the invention, a respiratory secretion retention (RSR) device configured to fluidly connect to an artificial airway can be provided. The respiratory secretion retention (RSR) device can include a housing that defines a passageway for the flow of respiratory gases, a chamber defined by the housing with a portion of the chamber configured to retain exhaled respiratory particulate and liquid, a patient side port coupled with the housing, which is in fluid communication with an artificial airway and at least one access port coupled with the housing were the at least one access port includes a control valve. In an aspect of this embodiment, the housing further can include an instillation port.

Abstract: It is an object of the resent invention to provide a multi-chamber container that has a weak seal portion having an increased joining strength and being easy to be opened when in administration of medicine, and that is provided at low cost. The multi-chamber container includes a medicine accommodation chamber 1, a diluting solution chamber 3 jointed to one side of the medicine accommodation chamber 1 via a partitioning weak seal portion 2, an unoccupied chamber 5 having a port 6 and joined to an opposite side of the medicine accommodation chamber 1 via a discharging weak seal portion 4, a film member 7 attached to the medicine accommodation chamber 1 for increasing a joining strength of each of the discharging weak seal portion 2 and the discharging weak seal portion 4, the discharging weak seal portion 4 having an easy-to-open portion 8 that enables the discharging weak seal portion 4 to easily opened therethrough.

Abstract: A portable blood storage device includes an outer housing an inner housing. The outer housing defines the structure of the blood storage device. The inner housing is located within the outer housing and has an interior cavity for storing collected blood and/or blood components. The inner housing has an open top to allow access to the interior cavity. The storage device also has an inlet duct and a return duct located within the interior cavity. The inlet duct is fluidly connectable to a cooling device and brings conditioned air into the storage device when fluidly connected to the cooling device. The return duct is also fluidly connectable to the cooling device and returns exhaust air to the cooling device when fluidly connected.

Abstract: A dispensing insert is configured to friction fit within a neck of a bottle and to selectively receive an oral syringe. The dispensing insert includes a hollow cylinder, a top plate capping one end of the hollow cylinder, a raised deck extending substantially parallel to and spaced from the top plate, and an annular side wall extending from the top plate upwardly toward the raised deck. The raised deck has a smaller outer diameter than the top plate and defines an opening therethrough configured to provide access to contents of the pharmacy bottle through the dispensing insert. The annular sidewall substantially encompasses an outer perimeter of the raised deck.

Abstract: Liquid drug transfer devices including a vented vial adapter having a top wall, a downward depending skirt, and a dual lumen puncturing spike. The top wall includes vent apertures in flow communication with an underlying air filter and protective hoods for covering the vent apertures from splashes. The hood-like hoods are preferably quarter sphere shaped with hood apertures facing radial outwards.

Abstract: A package assembly for a drug reconstitution assembly includes a body, a drug reconstitution assembly and a removable lid. The body includes a plurality of protrusions configured to mate with a plurality of corresponding features of the drug reconstitution assembly to inhibit axial and rotational translation of the drug reconstitution assembly and its constituent parts during shipping and handling. By preventing axial and rotational shifting during shipment, premature and accidental puncture or contamination of the medication or the spikes within the drug reconstitution assembly is minimized.

Abstract: Devices for the automatic release of liquid medicaments are disclosed. In particular, a flexible container for storing a liquid medicament, a port for such a flexible container, and a device for the automated release of a liquid medicament are disclosed. A flexible container for storing a medicament comprises sealed top and bottom flexible sheets and at least one port mounted to a wall of the flexible container. The at least one port comprises a flange attached to the wall and an inner conduit connecting the inner storage volume and the exterior of the flexible container. The port comprises an adapter protruding through a hole in the top flexible sheet and a base plate having at least one drain channel connected to the inner conduit via an inner opening on the base plate. A device for the automated release of a medicament comprises at least one flexible container.

Abstract: The invention relates generally to implantable drug delivery devices. Devices having a single drug chamber configuration, a divided drug chamber configuration and a compact dual-drug configuration are described. The devices have features to prevent clogging of the dispensing catheter and the creation of a local vacuum caused by the dispensing of the drug fluid. Also provided are features of a failsafe refilling process, automatic refill notification, and performance verification process. The divided drug chamber configuration enables frequent or continuous minute doses. A dual-drug chamber configuration uses self-locking refill containers to prevent mismatching between refill containers and drug chambers.

Abstract: Methods and devices for treatment of damaged tissue are disclosed, including treatment of wounds by employing non-electrically powered, reduced pressure therapy devices with a pressure oscillation mechanism. Maintenance and control of the sub atmospheric pressure exerted may be provided by such devices while minimizing discomfort to the user. The devices may be configured to be worn inconspicuously underneath clothing.

Abstract: A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Abstract: The invention refers to a new system for packaging pharmaceutical compositions comprising active principles that may be administered intravenously, in particular it concerns a system for packaging in bottles which makes it possible to ensure the complete transfer of the content of the bottle into the liquid for intravenous infusion and at the same time prevent any accidental contact with the active principle by the health-care personnel preparing said intravenous infusion, and a complete kit for intravenous administration.

Abstract: A connector assembly includes a first connector having a tubular first connector body, a hollow needle inside the first connector body and a first sealing component piercable by the needle, and a second connector having a tubular second connector body and a second sealing component. The second sealing component is in the second connector body, is attached to a first piercing section when inserted into the first connector body, and, in that state, is pierced by the needle together with the first piercing section. The connector assembly also includes a restriction which, when the second connector is inserted into the first connector, temporarily interrupts and restricts the insertion operation, but allows resumption of such operation when the restriction is removed, and which, when the second connector is withdrawn from the first connector, temporarily interrupts and restricts the withdrawing operation, but allows such operation to resume when the restriction is removed.

Abstract: The present invention relates to a plastic film for medical containers having an oxygen absorbing function including at least 4 layers (4) and formed by a co-extrusion method, and an infusion bag formed thereof, in which the 4 layers include: a first layer (1) constituted by a polyamide obtained by a ring-opening polymerization of a lactam 11 or more carbon atoms or by polycondensing of an ?-amino acid having 11 or more carbon atoms, or a polyamide obtained by copolycondensing a dicarboxylic acid having 10 or more carbon atoms and a diamine having 6 or more carbon atoms; a second layer (2) of a mixed composition that is adjacent to the first layer and contains an ethylene vinyl alcohol copolymer of an ?-olefin and a monomer of an unsaturated carboxylic acid or an anhydride of an unsaturated dicarboxylic acid as the major component, and a transition metal salt and a polyene-based polymer having an unsaturated double bond as accessory components; a third layer (3) that is adjacent to the second layer and contai

Abstract: A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom.

Abstract: A vial adapter is provided with a fitting portion which can be fitted into the head portion of a vial, and a hollow needle with a side hole. The base end portion of the needle is provided with a stopper contact portion which contacts the top surface of a stopper when the fitting portion is fitted in the head portion of the vial. When the fitting portion is fitted in the head portion of the vial, the stopper contact portion contacts the top surface of the stopper, and the fitting portion is fixed to the head portion of the vial by a claw engaging with the head portion of the vial, and further, the region of the side hole nearest the base end portion of the needle is positioned either roughly at the bottom surface of the stopper or inside of the stopper.

Abstract: A flushing device (8) usable in the catheterization of a bladder includes a flexible container (9) defining a compartment (12) adapted to be filled with a liquid, and a connector (10) attached to the container (9). The connector (10) is adapted to be connected to a catheter, and the connector (10) is provided with an opening (11). The flexible container (9) is interconnected with the connector (10) via a lumen (13), such that liquid is allowed to pass through the connector (10) in the lumen (13) from the flexible container (9) and exit through the opening (11). The flexible container further includes a non-return valve (14) arranged in the lumen (13). A kit including such flushing device (8) is also described.

Abstract: The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO2, and pO2, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Abstract: A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge.

Abstract: A surgical sponge and fluid monitoring system and method are provided. The system includes a support ring for securely supporting a container with at least one port opening for placing sponges into the container through the port opening with the aid of gravity. The support ring includes IR emitters and sensors that blanket IR beams across the port opening. The support ring is mechanically linked to a load cell in the system. The processor, with novel methods, reliably detects when sponges are placed into the container through the port opening, counts the number of sponges in the container, sorts the types of sponges, and calculates fluid loss for a patient in a surgical procedure. A user interface in the monitoring system keeps the medical professionals in the OR fully informed.

Abstract: Red blood cell products and compositions are disclosed. The product includes a container made from PVC or a non-PVC material that is substantially free of a phthalate plasticizer but otherwise includes one or more non-phthalate plasticizers or extractable agents. The product includes a RBC concentrate which has been combined with an additive solution for storing the RBCs.

Abstract: A vial adapter suitable for use in transferring fluid from a vial to a needleless syringe, the vial having a top end sealed with a septum.

Abstract: Veterinary compositions are described for controlling ecto- and endo-parasites in animals, such as bovine. The compositions contain an IGR compound(s) or a benzoyl substituted urea(s) along with a mineral mix and at least one carrier.

Abstract: A device for providing sterilized or cleaned fluid to a receptacle and thereby facilitate conveyance of a substance out of the receptacle, comprising a connector and a container which form an integrated unit. The connector is provided with a first means for connection to a receptacle. Sterilized or cleaned fluid is transferred from the container to the receptacle.

Abstract: A plastic ampule of the present invention is composed of a single layer of a plastic layer consisting only of a cyclic polyolefin with a glass transition temperature of 50° C. to 104° C.; integrally includes an ampule body formed in a bottle shape with a top part and a bottom part and having a bung for discharging a drug solution on the top part, a cap attached to the ampule body so as to seal the bung, and a thinner part having a layer thickness thinner than those of the ampule body and the cap, formed along a circumferential direction of the bung and connecting between the ampule body and the cap; and is opened by breaking off or twisting off the thinner part as a cutting part between the ampule body and the cap.

Abstract: A plastic ampule comprising a body portion, a head portion provided continuously to the mouth portion of the body portion through a cut-off portion, and a knob portion provided continuously to the head portion the ampule being unsealed by twisting the knob portion with fingers to cut the head portion off the mouth portion, wherein the hollow portion in the head portion is formed in the shape of a bowl. Since the hollow portion is formed in the shape of a bowl, content liquid remaining in the hollow portion can be discharged easily, the plastic ampule can be unsealed easily, and the content liquid remaining in the hollow portion is not scattered easily at the time of unsealing.

Abstract: The invention described herein pertains to a solid pharmaceutical composition comprising EC145 for reconstitution to provide a solution for intravenous injection, particularly to a lyophilized solid pharmaceutical composition comprising EC145 which has adequate stability for storage at ambient temperature and which is capable of redissolving in an aqueous diluent prior to administration, as well as a process for its manufacture, drug products comprising the composition and methods for using the composition for treating cancer.

Abstract: A collection device and a method for collecting a biological sample, particularly whole blood, includes a separating member to separate the whole blood into its components, and at least reagent positioned to selectively interact with a component of the separated sample. The reagent is able to selectively interact with the plasma/serum, and is prevented from contacting or interacting with the whole blood.

Abstract: A system for mixing the contents of a first container with the contents of a second container. The second container has a port assembly for receiving the first container. The port assembly has an actuator that is constructed to access the cavity of the first container during activation of the system and to allow fluid communication between the first container and the second container. The port assembly further includes a movable plug that provides a seal for the second container. The plug is configured to move axially relative to the actuator during activation of the system, thereby opening the seal of the second container and providing fluid communication between the first container and the second container.