Patents Represented by Attorney, Agent or Law Firm Celera
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6630337
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: October 7, 2003
    Assignee: Applera Corporation
    Inventors: Chunhua Yan, Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6630336
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: October 7, 2003
    Assignee: Applera Corporation
    Inventors: Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6630334
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: January 2, 2001
    Date of Patent: October 7, 2003
    Assignee: Applera Corporation
    Inventors: Karl Guegler, Marion Webster, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
    Patent number: 6620607
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the protease peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the protease peptides, and methods of identifying modulators of the protease peptides.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: September 16, 2003
    Assignee: Applera Corporation
    Inventors: Karl Guegler, Marion Webster, Chunhua Yan, Wei Shao, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human synthase proteins
    Patent number: 6620608
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: September 16, 2003
    Assignee: Applera Corporation
    Inventors: Fangcheng Gong, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human enzyme, nucleic acid molecules encoding human enzyme, and uses thereof
    Patent number: 6613554
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: September 2, 2003
    Assignee: Applera Corporation
    Inventors: Ming-Hui Wei, Chunhua Yan, Valentina DiFrancesco, Ellen M. Beasley
  • Isolated nucleic acid molecules encoding human aspartate aminotransferase protein and uses thereof
    Patent number: 6582935
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the aminotransferase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the aminotransferase peptides, and methods of identifying modulators of the aminotransferase peptides.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: June 24, 2003
    Assignee: Applera Corporation
    Inventors: Chunhua Yan, Weiniu Gan, Trevor Woodage, Karen A Ketchum, Valentina Di Francesco, Ellen M Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6582946
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: June 24, 2003
    Assignee: Applera Corporation
    Inventors: Marion Webster, Ming-Hui Wei, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6579709
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: June 17, 2003
    Assignee: Applera Corporation
    Inventors: Karl Guegler, Ellen M. Beasley, Valentina Di Francesco
  • Isolated human enzyme proteins, nucleic acid molecules encoding human enzyme proteins, and uses thereof
    Patent number: 6555351
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: April 29, 2003
    Assignee: Applera Corporation
    Inventors: Ellen M. Beasley, Gennady V. Merkulov, Valentina Di Francesco
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6555352
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: April 29, 2003
    Assignee: Applera Corporation
    Inventors: Marion Webster, Zhenya Li, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human phosphatase proteins, nucleic acid molecules encoding human phophatase proteins, and uses thereof
    Patent number: 6551809
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: April 22, 2003
    Assignee: Applera Corporation
    Inventors: Chunhua Yan, Weiniu Gan, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human dehydrogenase proteins, nucleic acid molecules encoding these human dehydrogenase proteins, and uses thereof
    Patent number: 6544764
    Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the dehydrogenase polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the dehydrogenase polypeptides, and methods of identifying modulators of the dehydrogenase polypeptides.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: April 8, 2003
    Assignee: Applera Corporation
    Inventors: Chunhua Yan, Zhenya Li, Gennady V Merkulov, Valentina Di Francesco, Ellen Beasley
  • Isolated nucleic acid molecules encoding transferase enzymes
    Patent number: 6537780
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: March 25, 2003
    Assignee: Applera Corporation
    Inventors: Ellen M. Beasley, Karen A. Ketchum, Valentina Di Francesco
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6537788
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: March 25, 2003
    Assignee: Applera Corporation
    Inventors: Jane Ye, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
    Patent number: 6531297
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: March 11, 2003
    Assignee: Applera Corporation
    Inventors: Gennady V. Merkulov, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6528294
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: February 1, 2002
    Date of Patent: March 4, 2003
    Assignee: Applera Corporation
    Inventors: Jiayin Li, Karl Guegler, Ellen M. Beasley, Karen A. Ketchum, Valentina Di Francesco
  • Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
    Patent number: 6518055
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the protease peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the protease peptides, and methods of identifying modulators of the protease peptides.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: February 11, 2003
    Assignee: Applera Corporation
    Inventors: Weiniu Gan, Jane Ye, Valentina Di Francesco, Ellen M. Beasley
  • Isolated nucleic acid encoding a human lactate dehydrogenase and uses thereof
    Patent number: 6503743
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the secreted peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the secreted peptides, and methods of identifying modulators of the secreted peptides.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: January 7, 2003
    Assignee: PE Corporation
    Inventors: Steven I. Ladunga, Eugene Spier, Maureen Higgins, Simon Greenberg, Yu Wang
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6500655
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: December 31, 2002
    Assignee: Applera Corporation
    Inventors: Douglas Rusch, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley