Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
July 31, 2002
Date of Patent:
June 22, 2004
Assignee:
Applera Corporation
Inventors:
Jane Abu-Threideh, Fangcheng Gong, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
Type:
Grant
Filed:
March 14, 2001
Date of Patent:
June 1, 2004
Assignee:
Applera Corporation
Inventors:
Weiniu Gan, Jane Ye, Valentina Di Francesco, Ellen M Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the secreted peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the secreted peptides, and methods of identifying modulators of the secreted peptides.
Type:
Grant
Filed:
April 25, 2001
Date of Patent:
May 25, 2004
Assignee:
Applera Corporation
Inventors:
Ellen M Beasley, Ming-Hui Wei, Fangcheng Gong, Steven I Ladunga, Maureen E Higgins
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
May 1, 2002
Date of Patent:
May 25, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Karen A. Ketchum, Valentina Difrancesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of human lanosterol synthase proteins and nucleic acid sequences encoding these lanosterol synthase proteins. The present invention provides isolated lanosterol synthase proteins and encoding nucleic acid molecules, vectors and host cells containing these nucleic acid molecules, and processes for producing the lanosterol synthase proteins.
Type:
Grant
Filed:
March 23, 2001
Date of Patent:
May 18, 2004
Assignee:
Applera Corporation
Inventors:
Ming-Hui Wei, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
January 10, 2003
Date of Patent:
May 11, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
Type:
Grant
Filed:
February 21, 2001
Date of Patent:
May 11, 2004
Assignee:
Applera Corporation
Inventors:
Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
August 21, 2002
Date of Patent:
May 4, 2004
Assignee:
Applera Genomics
Inventors:
Chunhua Yan, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
Type:
Grant
Filed:
June 6, 2002
Date of Patent:
May 4, 2004
Assignee:
Applera Corporation
Inventors:
Karl Guegler, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
Type:
Grant
Filed:
April 2, 2001
Date of Patent:
April 20, 2004
Assignee:
Applera Corporation
Inventors:
Ellen M. Beasley, Marion Webster, Valentina Di Francesco, Ming-Hui Wei
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
Type:
Grant
Filed:
August 28, 2002
Date of Patent:
April 20, 2004
Assignee:
Applera Corporation
Inventors:
Ming-Hui Wei, Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
March 30, 2001
Date of Patent:
April 6, 2004
Assignee:
Applera Corporation
Inventors:
Wei Shao, Gennady V. Merkulov, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
Type:
Grant
Filed:
February 1, 2002
Date of Patent:
March 30, 2004
Assignee:
Applera Corporation
Inventors:
Marion Webster, Ming-Hui Wei, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
Type:
Grant
Filed:
April 1, 2002
Date of Patent:
March 23, 2004
Assignee:
Applera Corporation
Inventors:
Wei Shao, Gennady V. Merkulov, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
September 16, 2002
Date of Patent:
March 16, 2004
Assignee:
Applera Corporation
Inventors:
Marion Webster, Chunhua Yan, Valentina Di Francesco, Ellen Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
October 21, 2002
Date of Patent:
March 16, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Zhenya Li, Beena Neelam, Valentina DiFrancesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
Type:
Grant
Filed:
February 24, 2003
Date of Patent:
February 17, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Weiniu Gan, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
October 29, 2002
Date of Patent:
February 17, 2004
Assignee:
Applera Corporation
Inventors:
Ming-Hui Wei, Kabir Chaturvedi, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phospholipase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phospholipase peptides, and methods of identifying modulators of the phospholipase peptides.
Type:
Grant
Filed:
March 14, 2002
Date of Patent:
February 10, 2004
Assignee:
Applera Corporation
Inventors:
Karl Guegler, Ellen M. Beasley, Karen A. Ketchum, Valentina Di Francesco
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
May 1, 2002
Date of Patent:
February 10, 2004
Assignee:
Applera Corporation
Inventors:
Ishwar Chandramouliswaran, Karl Guegler, Marion Webster, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley