Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir and AZT and 2-amino-9-(2-hydroxyethoxymethyl)purine or an ester thereof.

Abstract: The present invention relates to bezoquinazoline thymidylate synthase inhibitors, to pharmaceutical formulations containing them and to their use in medicine.

Abstract: Treatment of animals or humans carrying or infected with HTLV-I, HTLV-I (including HTLV-I-associated leukemias or lymphomas), non-A, non-B hepatitis virus, hepatitis B virus, EBV, equine infectious anaemia or other lentiviruses or having antibodies to said viruses is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.

Abstract: Compounds or formula (I), wherein R.sup.1 represents an n-propoxy, cyclobutoxy, cyclopropylamino, piperidino or pyrrolidino group; or a physiologically functional derivative thereof. The invention further includes methods for the preparation of compounds of formula (I), compositions containing them and the use of these compounds as antiviral agents.

Abstract: A water-dispersible tablet comprises lamotrigine, a pharmaceutically acceptable swellable clay and an additional disintegrating agent. The swellable clay and an additional disintegrating agent. The swellable clay is a smectite, e.g. Veegum F or bentonite, and is present within the granules of the tablet to provide a tablet which is capable of dispersing in water within 3 minutes to provide a dispersion which will pass through a 710 .mu.m sieve. The tablet can be optionally film-coated in which case the dispersion time is less than 5 minutes.

Abstract: A swing phase control device for an artificial knee joint which is provided with different first and second throttle controls to permit more natural flexing and stretching of the knee joint.

Abstract: This application discloses a method of inhibiting degradation of the antidepressant bupropion hydrochloride in a solid pharmaceutical formulation, so that the pharmaceutical formulation will maintain at least 80% of its initial bupropion potency after one year.

Abstract: A method for producing an object by layerwise solidification of the object by means of electromagnetic radiation is expedited by simultaneously solidifying the material of a layer at a plurality of places.An apparatus for carrying out the method comprises an irradiation device (11, 12, 14, 15, 16) generating a plurality of beams (20, 21, 22) as well as a control device (7, 17, 18, 19) directing each of the plurality of beams independently to different regions of the layer (8a . . . 8d).

Abstract: An infusion supply apparatus is provided which is attachable to a stationary apparatus such as an overhead support (1), on the one hand, and with a patient transporting apparatus (3), on the other hand. The transfer from one such apparatus to the other shall be possible in a simple and locked manner. To this end, the stationary apparatus (1), the patient transport apparatus (3) and a handle (12) each have a coupling member (2, 4, 13) and a support (7) for the medical appliances comprises a coupling (8) cooperating with respective two such coupling members. The coupling (8) comprises a lock means (16, 17) which unlocks in case of engagement of two coupling members in the coupling means for selective detachment of an engagement and locks in case of engagement of a single one of the coupling members.

Abstract: This invention relates to the use of a class of compounds as immunopotentiaters, compositions containing such compounds and their manufacture, combinations of such compounds with anti-tumor or anti-infective drugs and the use of such combinations in the prophylaxis or treatment of such diseases arising from tumors or infections.