Abstract: The invention relates to a controlled release pharmaceutical formulation for oral administration which comprises discrete units comprising acrivastine or a salt thereof coated with a mixture containing:a) a copolymer or polymer containing repeating monomer units selected from alkyl esters of acrylic and methacrylic acids andb) ethyl cellulose,and a process for preparing such formulations.
Type:
Grant
Filed:
September 8, 1993
Date of Patent:
December 6, 1994
Assignee:
Burroughs Wellcome Co.
Inventors:
Harry P. Jones, Robert J. Mackey, Michael J. D. Gamlen
Abstract: This application discloses a method of inhibiting degradation of the antidepressant bupropion hydrochloride in a solid pharmaceutical formulation, so that the pharmaceutical formulation will maintain at least 80% of its initial bupropion potency after one year.
Type:
Grant
Filed:
August 12, 1993
Date of Patent:
October 25, 1994
Assignee:
Burroughs Wellcome Co.
Inventors:
Michael D. Ruff, Sanyasi R. Kalidindi, Joel E. Sutton, Jr.
Abstract: A magneto-optical disk comprising a substrate whereon a recording medium is formed, and a depression is formed on the substrate on the inside of the recording medium of the substrate. A center hub is installed on the depression such that the center hub is substantially level with a protective resin layer covering the recording medium. On the center hub, a flying head performs CSS (Contact Start and Stop). This configuration of the disk eliminates the occurrence of dust due to the abrasion and head crash, and achieves stable CSS. A method of manufacturing the magneto-optical disk, wherein the protective resin layer is formed after installing the center hub on the depression. In this method, since a space is not produced between the center hub and the protective resin layer, the stable flying characteristics is obtained. And a magneto-optical disk whereon small physical bumps and pits are formed on the substrate on the inside of the recording medium, which prevents the flying head from sticking to the disk.
Abstract: A portable, closed circuit, disposable device for post operatory surgical suction which comprised a bellows-shaped body receptacle for suctioned fluids, a threaded neck located on the upper surface of said bellows-shaped body suitable to receive a threaded cap; said cap being provided with a suction tube system connected through said cap into the bellows-shaped body, and said system of tubes is provided with a check-valve, wherein said bellows-shaped body is provided with a cannula in its lower surface, having a nearly rectangular longitudinal section, having a lower end wall, wherein the side wall of said cannula is provided with at least one opening located in a position close to said lower end wall of said cannula; where an elastic tube, with a longer extension than said cannula, is introduced under pressure in said cannula in order to close the at least one opening of said cannula, and wherein a tube of rigid or semi-rigid material is introduced in said cannula, fixing the elastic tube between its interio
Abstract: A knee orthesis comprises a thigh attachment part, a lower leg attachment part and a joint hingedly connecting both parts, In order to improve the wearing characteristics the knee orthesis comprises a diagonal strut which connects an outer upper point of the thigh attachment part to an inner lower point of the thigh attachment part by extending around the front side of the thigh.
Abstract: A expandable police baton embodying a cylindrical sleeve within which is slidably disposed a cylindrical shaft. The sleeve and shaft are formed with flats to prevent rotation of the shaft within the sleeve. The baton also includes a shock absorbing assembly positioned on the shaft.
Abstract: A method for forming an image in which image data defined of three original colors for forming a full color image is written in a mass of three kind of liquid crystal cells by beam light and the image is read by irradiating each liquid crystal cell with light corresponding to each of three original colors and printed out, the method including the steps of writing the image data into each liquid crystal cell by scanning beam light in a primary scanning direction and moving in a secondary scanning direction the three kind of liquid crystal cells arranged in the secondary scanning direction, and reading the image data by irradiating the liquid crystal cell with light of original colors while moving the mass of the liquid crystal cells in a direction opposite to that at the time of image writing.
Abstract: The present invention relates to amino acid esters of pyrimidine and purine nucleosides containing an acyclic side chain, and their use in medical therapy, particularly the treatment of herpes virus infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.
Abstract: A Lombard voice recognition method for recognizing a voice input in a noisy background includes a step of matching and a step of warping. The step of matching matches a frequency spectrum of a feature pattern derived from the input voice to a frequency spectrum of a standard pattern. The step of warping warps a lower frequency spectrum of the feature pattern than a lower frequency side with respect to a frequency axis in case that a noise level of the background in higher than a predetermined noise level.
Abstract: A method for treating or preventing a Pneumocystis carinii infection in a mammal by administering a certain naphthoquinone compound or physiologically acceptable salts thereof.
Type:
Grant
Filed:
November 22, 1991
Date of Patent:
May 10, 1994
Assignee:
Burroughs Wellcome Co.
Inventors:
Victoria S. Latter, Winston E. Gutteridge, Alan T. Hudson
Abstract: An infusion supply apparatus is provided which can be connected with a stationary apparatus such as an overhead support (1) on the one hand, and with a patient transporter (3) on the other hand. In order to allow an easy and locking transfer from one such apparatus to the other the stationary apparatus (1), the patient transporter (3) and a mobile chassis (5) each have a coupling member (2, 4, 9) and a support for the medical appliances has a coupler system (13) cooperating with respective two such coupling members. The coupling system (13) comprises a locking apparatus (19, 20) which unlocks for selective release of an engagement if two coupling members engage the coupling system and which locks upon engagement of a single coupling member.
Abstract: In a line connector system an incorrect interconnection of different lines shall be excluded. This is achieved by connecting a female connector (1-3, 1-6) to one line and a male plug (2-3, 2-6) to the other line, the female connector and male plug having a defined total length when connected; the total length may for example exactly correspond to the distance between two holding members (4, 5) of a holder (3) which receives the connected coupling members with the lines connected thereto. The individual female connectors and male plugs, respectively, have a respective different length such that the total length of incorrect coupling members in a connected state deviate from the predetermined length, whereby for example an insertion of the connected coupling members into the holder is impossible.
Abstract: A method of controlling veterinary ectoparasites of mammals and birds of the sub-Orders Ixodoidea and Sarcoptiformes comprising the application of a parasiticidally effective, non-toxic amount of a pyrethroid of formula ##STR1## together with at least one parasiticidal organophosphoruscompound active against said ectoparasites.
Abstract: The present invention is concerned with compounds of formula (I) ##STR1## wherein m is 0 or 1;W is hydrogen, a C.sub.1-16 straight, branched, or cyclic alkyl group, or a C.sub.2-16 straight, branched, or cyclic alkenyl or alkynyl group, or Ph(CH.sub.2).sub.n -- where Ph is phenyl and n is an integer of from 0 to 2, the phenyl group being optionally substituted by one or more atoms or groups independently selected from halogen, hydroxy, nitro, C.sub.1-4 alkoxy and C.sub.1-4 alkyl wherein one or more of the hydrogen atoms in said alkyl group is optionally replaced by halogen, or R.sup.1 NHCO-- where R.sup.1 is hydrogen or a C.sub.1-6 alkyl group, or R.sup.2 CONH-- where R.sup.2 is hydrogen or a C.sub.1-6 alkyl group; X is ##STR2## where A is halogen; Y is --(CH.sub.2).sub.q, where q is an integer of from 1 to 3, or --CH.dbd.CH-- (E or Z);Z is a C.sub.
Type:
Grant
Filed:
November 5, 1992
Date of Patent:
March 1, 1994
Assignee:
Burroughs Wellcome Co.
Inventors:
William P. Jackson, Clifford J. Harris, Richard J. Arrowsmith, John G. Dann, Kevin J. O'Connor, Robert F. G. Booth
Abstract: A topical liquid formulation for treating lice or head infection is disclosed. The formulation contains active ingredients such as deltamethrin or permethrin in a lower alkyl ether of glycol.