Patents Represented by Attorney Edward A. Conroy, Jr.

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  • 1-Benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)-urea, a novel and useful intermediate for the preparation of animal growth promoting agents
    Patent number: 4051183
    Abstract: This invention relates to 1-benzoyl (and 1-substituted benzoyl)-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)ureas, novel and useful intermediates for the preparation of 1,2,3,4-tetrahydro-4-oxo-1-naphthylurea and certain derivatives thereof. The above tetrahydro-4-oxo-1-naphthyl-urea and certain derivatives thereof are animal growth promoting agents.This invention further relates to methods of preparation of said 1-benzoyl (and 1-substituted benzoyl) 3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)ureas.
    Type: Grant
    Filed: September 2, 1976
    Date of Patent: September 27, 1977
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • Novel 1,2,3,4-tetrahydro-4-oxo-(oxy)-1-naphthylamines and method of preparation thereof
    Patent number: 4049717
    Abstract: This disclosure describes 1,2,3,4-tetrahydro-4-oxo-(oxy)-1-naphthylamine and novel derivatives thereof and methods of preparation of said compounds. These novel compounds are useful and valuable intermediates for the preparation of 1,2,3,4-tetrahydro-4-oxo(oxy)-1-naphthylurea and thiourea compounds and certain derivatives thereof which are animal growth promoters.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: September 20, 1977
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • Alkylated derivatives of antibiotic BM123.gamma.
    Patent number: 4048431
    Abstract: This disclosure describes a novel series of potent antibacterial agents derived by reductive alkylation of antibiotic BM123.gamma. with certain classes of aldehydes and ketones.
    Type: Grant
    Filed: November 10, 1975
    Date of Patent: September 13, 1977
    Assignee: American Cyanamid Company
    Inventors: Joseph John Hlavka, Panayota Bitha
  • Compositions containing 4,5,6,7-tetrahydrobenz[b]thien-4-yl-ureas or derivatives and methods of enhancing growth rate
    Patent number: 4036979
    Abstract: This disclosure describes a novel method for improving feed efficiency and accelerating the growth rate of veterinary homothermic animals by administering to said animals a growth-promoting amount of a cycloalkano[b]thien-4-ylurea or thiourea.
    Type: Grant
    Filed: April 12, 1976
    Date of Patent: July 19, 1977
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • 1-(Para-substituted-phenyl)-1H-tetrazoles
    Patent number: 4036849
    Abstract: This disclosure describes compounds of the class of 1-(para-substituted-phenyl)-1H-tetrazoles useful as antimicrobial agents.
    Type: Grant
    Filed: November 10, 1975
    Date of Patent: July 19, 1977
    Assignee: American Cyanamid Company
    Inventors: William Vincent Curran, Andrew Stephen Tomcufcik, Adma Schneller Ross
  • Novel compounds of the 11-deoxyprostaglandin E.sub.3, R.sub.3.sub..alpha., and F.sub.3.sub..beta. series
    Patent number: 4033992
    Abstract: This disclosure describes compounds of the 11-deoxyprostaglandin E.sub.2, F.sub.2.sub..alpha., F.sub.2.sub..beta., E.sub.3, F.sub.3.sub..alpha., and F.sub.3.sub..beta. series having bronchodilator activity.
    Type: Grant
    Filed: December 29, 1975
    Date of Patent: July 5, 1977
    Inventors: Charles Vincent Grudzinskas, Martin Joseph Weiss
  • 2,3-Bis(4-alkyl-1-piperazinyl)quinoxalines
    Patent number: 4029788
    Abstract: This disclosure describes compounds of the class of 5- or 6-substituted 2,3-bis(4-alkyl-1-piperazinyl)quinoxalines useful for ameliorating cecal and hepatic amebic infestations in warm-blooded animals.
    Type: Grant
    Filed: July 16, 1976
    Date of Patent: June 14, 1977
    Assignee: American Cyanamid Company
    Inventors: Paul Frank Fabio, Yang-I Lin, Stanley Albert Lang, Jr., Andrew Stephen Tomcufcik
  • 16,16-Spirocycloalkyl prostaglandin derivatives
    Patent number: 4028396
    Abstract: This disclosure describes novel 15-hydroxy-16,16-spirocycloalkyl prostanoic acids and derivatives and congeners thereof which are useful as bronchodilators and gastric acid secretion inhibitors.
    Type: Grant
    Filed: July 2, 1975
    Date of Patent: June 7, 1977
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Schaub, Martin Joseph Weiss
  • Antibacterial agents cis-BM123.gamma..sub.1 and cis-BM123.gamma..sub.2
    Patent number: 4018972
    Abstract: This disclosure describes two new antibacterial agents designated cis-BM123.gamma..sub.1 and cis-BM123.gamma..sub.2 produced by a novel photolytic process whereby trans-BM123.gamma..sub.1 and trans-BM123.gamma..sub.2 are transformed to their corresponding cis-isomers. The new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found.
    Type: Grant
    Filed: March 8, 1976
    Date of Patent: April 19, 1977
    Assignee: American Cyanamid Company
    Inventor: Joseph John Hlavka
  • 3-Alkyl-2-(6-carboxyhexyl)cyclopentanones and esters and salts thereof
    Patent number: 4018811
    Abstract: This disclosure describes compounds of the class of substituted 9-oxoprostanoic acids and the esters and cationic salts thereof, useful as antimicrobial agents, hypotensive agents, anti-ulcer agents, or as intermediates, and novel processes for preparing the same.
    Type: Grant
    Filed: April 3, 1972
    Date of Patent: April 19, 1977
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Schaub, Karel Francis Bernady, Martin Joseph Weiss
  • 16-Fluoro-11-deoxy-13-dihydro-prostaglandin
    Patent number: 4017534
    Abstract: This disclosure describes novel 11-deoxy-13,14-dihydro-prostaglandin-9-ketals useful as bronchodilators and as gastric acid secretion inhibitors.
    Type: Grant
    Filed: October 14, 1975
    Date of Patent: April 12, 1977
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Schaub, Middleton Brawner Floyd, Jr., Martin Joseph Weiss
  • 1-(Para-substituted-phenyl)-1H-tetrazoles
    Patent number: 4010179
    Abstract: This disclosure describes compounds of the class of 1-(para-substituted-phenyl)-1H-tetrazoles which possess anti-microbial and anti-neoplastic activity.
    Type: Grant
    Filed: November 10, 1975
    Date of Patent: March 1, 1977
    Assignee: American Cyanamid Company
    Inventors: William Vincent Curran, Andrew Stephen Tomcufcik, Adma Schneller Ross
  • Novel 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanates
    Patent number: 4007210
    Abstract: This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: September 18, 1975
    Date of Patent: February 8, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • Antibiotic BM123 and production thereof
    Patent number: 4007167
    Abstract: This disclosure describes 5 new antibacterial agents designated BM123.alpha., BM123.beta. .sub.1, BM123.beta..sub.2, BM123.gamma..sub.1, and BM123.gamma..sub.2 produced in a microbiological fermentation under controlled conditions using a new strain of an undetermined species of Nocardia and mutants thereof. The new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found.
    Type: Grant
    Filed: August 21, 1975
    Date of Patent: February 8, 1977
    Assignee: American Cyanamid Company
    Inventors: John Henry Edward James Martin, Homer David Tresner, John Norman Porter
  • Ureidotetralin compounds
    Patent number: 4005140
    Abstract: This invention relates to ureidotetralin compounds and derivatives and selected enantiomers thereof. This invention also relates to methods for the preparation of said compounds which are useful as animal growth regulators and/or herbicidal agents.
    Type: Grant
    Filed: January 26, 1976
    Date of Patent: January 25, 1977
    Assignee: American Cyanamid Company
    Inventors: Larry Dean Spicer, Joseph Michael Pensack, Robert Daniel Wilbur, Gary Michael Demkovich
  • Novel prostaglandins
    Patent number: 3993674
    Abstract: This disclosure describes novel 15-hydroxy prostanoic acid derivatives having anti-ulcer, bronchodilator, and hypotensive activity.
    Type: Grant
    Filed: March 4, 1975
    Date of Patent: November 23, 1976
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Schaub, Martin Joseph Weiss
  • 11.alpha.-HOMO-PROSTANOIC ACIDS AND ESTERS
    Patent number: 3985798
    Abstract: This disclosure describes 11.alpha.-homo-prostanoic acid derivatives which are useful as gastric acid secretion inhibitors.
    Type: Grant
    Filed: January 27, 1975
    Date of Patent: October 12, 1976
    Assignee: American Cyanamid Company
    Inventors: Middleton Brawner Floyd, Jr., Martin Joseph Weiss
  • Derivatives of 9-oxo-13-trans-prostenoic acid amides
    Patent number: 3981868
    Abstract: This disclosure described homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenamide and of 9-hydroxy-13-trans-prostenamide, having antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: January 10, 1974
    Date of Patent: September 21, 1976
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • 2-Substituted-3,4-epoxycyclopentan-1-ones, and 2-substituted-3,4-epoxycyclopentan-1-ols
    Patent number: 3966773
    Abstract: This disclosure describes 2-substituted-3,4-epoxy-cyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: August 11, 1975
    Date of Patent: June 29, 1976
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • D-3,6-Diaminohexanoic acid 2-(carboxymethyl)-2-methylhydrazide, process of preparing and intermediates of said process
    Patent number: 3962317
    Abstract: This disclosure describes D-3,6-diaminohexanoic acid 2-(carboxymethyl)-2-methylhydrazide which is useful as an antibacterial agent.
    Type: Grant
    Filed: August 19, 1974
    Date of Patent: June 8, 1976
    Assignee: American Cyanamid Company
    Inventor: William Vincent Curran